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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027260192.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260192", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260192" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR46", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR46" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Hrh4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR46", "locus": {} } ], "crossref": [ { "id": "100774770", "url": "https://www.ncbi.nlm.nih.gov/gene/100774770", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774770", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774770", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MR46", "url": "https://www.orthodb.org/?gene=A0A8C2MR46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24247:SF199", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24247:SF199", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027260192", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260192", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MR46", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MR46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLDANGTGSLPLTAKVPLAFLMSLLAFSIMLGNAVVILAFVVDKDLRHRSNYFFLNLAISDFFVGMISIPLYIPHTLFNWNFGSEICMFWLITDYLLCTASVYNIVLISYDRYQSVSNAVSYRAQHTSIVKIVAQMVVVWILAFLVNGPMILASDSWKNNTSIKECEPGFVTEWYILAITSFLEFLVPIISVAYFNVKIYWSLWKRGSLSRCPSCAAFISTSSSDSGHLPRAGVASRTSLPTSKEAATSFHSESPQRKSSLLVSLRTHMNSSITAFKVGSFSRSETLALHQREHMELLRGRKLARSLAILLTAFGICWAPYCLFTIVLSTYPKGKRPKSVWYNIAFWLQWFNSFVNPFLYPLCHKRFQKAFWKIFCVKKQPTLSQNQSVSS", "length": 391, "header": "tr|A0A8C2MR46-1|A0A8C2MR46_CRIGR Isoform 1 of Histamine H4 receptor isoform X2 OS=Cricetulus griseus OX=10029 GN=Hrh4 PE=3 SV=1 CANONICAL=A0A8C2MR46-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MR46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR46/entry#A0A8C2MR46-1", "sequence": { "sequence": "MLDANGTGSLPLTAKVPLAFLMSLLAFSIMLGNAVVILAFVVDKDLRHRSNYFFLNLAISDFFVGMISIPLYIPHTLFNWNFGSEICMFWLITDYLLCTASVYNIVLISYDRYQSVSNAVSYRAQHTSIVKIVAQMVVVWILAFLVNGPMILASDSWKNNTSIKECEPGFVTEWYILAITSFLEFLVPIISVAYFNVKIYWSLWKRGSLSRCPSCAAFISTSSSDSGHLPRAGVASRTSLPTSKEAATSFHSESPQRKSSLLVSLRTHMNSSITAFKVGSFSRSETLALHQREHMELLRGRKLARSLAILLTAFGICWAPYCLFTIVLSTYPKGKRPKSVWYNIAFWLQWFNSFVNPFLYPLCHKRFQKAFWKIFCVKKQPTLSQNQSVSS", "length": 391, "header": "tr|A0A8C2MR46-1|A0A8C2MR46_CRIGR Isoform 1 of Histamine H4 receptor isoform X2 OS=Cricetulus griseus OX=10029 GN=Hrh4 PE=3 SV=1 CANONICAL=A0A8C2MR46-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR46", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR46" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"https://www.uniprot.org/uniprotkb/A0A8C2MR46" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR46", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR46" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR46", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR46" } ], "pmid": "" }, { "name": "adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway", "id": "GO:0007197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007197", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR46", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR46" } ], "pmid": "" }, { "name": "positive regulation of cytosolic calcium ion concentration", "id": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J9Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRAGGGWNRGRMLAAGEAGQEPAAPCCPEGGDRVKNAEEKSDMSIAALVGSDQLTQDGDDDELLLSVSAFIEKEVGSDLKSLKKLGKLIEKMTEDKIKLEEQVLTISSEIPKRIQSALKDAEESKQVLNQFLEQEAPLFSSITSHLLTAQPWMDDLGAMITQIEEIEQHLTYLKWVSQIEELSDNIQQYLMTNNVPEAASILVTMTELDIKLQESSCTHLLSFVRATVKFWHKILKDKLTSDFEEILAQLHWPFITHTQSQAVGINWPAGAPEIYGTLETLFCQLLKLQASDELLTEQKQLPEKYSLPECPSVILPIQIMLTPLQKRFKYHFRGSRQTNVISKPEWYLAQVLMWIGSHAHFLDEKIQPILDKAGCAVNARLEFSRGLVMLILEKLASDIPCLLYDDNLFCHLVDEVLLFERELHSVHGYPSTFASCMHILSEETCFQRWLTVERKFALQKMDSMLSSEAVWVSQYKDITDVDEMKVPDCAEVFMTLLLVITDRYKNLPTAPRKLQFLELQKDLVDDFRIRLTQVMKEETRAPLDFRYCAILNAVNYISTVLADWADNVFFLQLQQAALEVFAENNALSKLQLGQLASMESSVFDDMINLLERLKLDMLTRQVDHVFREVKDAAKLYKKERWLSLPSQCEQAVMSLSSSACPLLLTLRDRLLQLEQQLCFSLFRVFWQMLVEKLDMYIYQEIILANHFNEGGAAQLQFDMTRNLFPLFSHYCKRPENYFKHVKEACIILNLNIGSALLLKDVLQSASEHLSATAALNEVGIYKLAQQDVEILLNLRTNWPNTGK", "length": 804, "header": "tr|A0A8C2MR48-1|A0A8C2MR48_CRIGR Isoform 1 of RAD50-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Rint1 PE=3 SV=1 CANONICAL=A0A8C2MR48-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MR48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR48/entry#A0A8C2MR48-1", "sequence": { "sequence": "MSRAGGGWNRGRMLAAGEAGQEPAAPCCPEGGDRVKNAEEKSDMSIAALVGSDQLTQDGDDDELLLSVSAFIEKEVGSDLKSLKKLGKLIEKMTEDKIKLEEQVLTISSEIPKRIQSALKDAEESKQVLNQFLEQEAPLFSSITSHLLTAQPWMDDLGAMITQIEEIEQHLTYLKWVSQIEELSDNIQQYLMTNNVPEAASILVTMTELDIKLQESSCTHLLSFVRATVKFWHKILKDKLTSDFEEILAQLHWPFITHTQSQAVGINWPAGAPEIYGTLETLFCQLLKLQASDELLTEQKQLPEKYSLPECPSVILPIQIMLTPLQKRFKYHFRGSRQTNVISKPEWYLAQVLMWIGSHAHFLDEKIQPILDKAGCAVNARLEFSRGLVMLILEKLASDIPCLLYDDNLFCHLVDEVLLFERELHSVHGYPSTFASCMHILSEETCFQRWLTVERKFALQKMDSMLSSEAVWVSQYKDITDVDEMKVPDCAEVFMTLLLVITDRYKNLPTAPRKLQFLELQKDLVDDFRIRLTQVMKEETRAPLDFRYCAILNAVNYISTVLADWADNVFFLQLQQAALEVFAENNALSKLQLGQLASMESSVFDDMINLLERLKLDMLTRQVDHVFREVKDAAKLYKKERWLSLPSQCEQAVMSLSSSACPLLLTLRDRLLQLEQQLCFSLFRVFWQMLVEKLDMYIYQEIILANHFNEGGAAQLQFDMTRNLFPLFSHYCKRPENYFKHVKEACIILNLNIGSALLLKDVLQSASEHLSATAALNEVGIYKLAQQDVEILLNLRTNWPNTGK", "length": 804, "header": "tr|A0A8C2MR48-1|A0A8C2MR48_CRIGR Isoform 1 of RAD50-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Rint1 PE=3 SV=1 CANONICAL=A0A8C2MR48-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F5U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR48/entry#A0A9J7F5U5-1", "sequence": { "sequence": "MESRQDARSWRSGPGAGGPGDMSIAALVGSDQLTQDGDDDELLLSVSAFIEKEVGSDLKSLKKLGKLIEKMTEDKIKLEEQVLTISSEIPKRIQSALKDAEESKQVLNQFLEQEAPLFSSITSHLLTAQPWMDDLGAMITQIEEIEQHLTYLKWVSQIEELSDNIQQYLMTNNVPEAASILVTMTELDIKLQESSCTHLLSFVRATVKFWHKILKDKLTSDFEEILAQLHWPFITHTQSQAVGINWPAGAPEIYGTLETLFCQLLKLQASDELLTEQKQLPEKYSLPECPSVILPIQIMLTPLQKRFKYHFRGSRQTNVISKPEWYLAQVLMWIGSHAHFLDEKIQPILDKAGCAVNARLEFSRGLVMLILEKLASDIPCLLYDDNLFCHLVDEVLLFERELHSVHGYPSTFASCMHILSEETCFQRWLTVERKFALQKMDSMLSSEAVWVSQYKDITDVDEMKVPDCAEVFMTLLLVITDRYKNLPTAPRKLQFLELQKDLVDDFRIRLTQVMKEETRAPLDFRYCAILNAVNYISTVLADWADNVFFLQLQQAALEVFAENNALSKLQLGQLASMESSVFDDMINLLERLKLDMLTRQVDHVFREVKDAAKLYKKERWLSLPSQCEQAVMSLSSSACPLLLTLRDRLLQLEQQLCFSLFRVFWQMLVEKLDMYIYQEIILANHFNEGGAAQLQFDMTRNLFPLFSHYCKRPENYFKHVKEACIILNLNIGSALLLKDVLQSASEHLSATAALNEVGIYKLAQQDVEILLNLRTNWPNTGK", "length": 782, "header": "tr|A0A9J7F5U5-1|A0A8C2MR48_CRIGR Computationally mapped isoform of RAD50-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Rint1 PE=3 SV=1 CANONICAL=A0A8C2MR48-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J556-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR48/entry#A0A9J7J556-1", "sequence": { "sequence": "MSRAGGGWNRGRMLAAGEAGQEPAAPCCPEGGDRVKNAEEKSDMSIAALVGSDQLTQDGDDDELLLSVSAFIEKEVGSDLKSLKKLGKLIEKMTEDKIKLEEQVLTISSEIPKRIQSALKDAEESKQVLNQFLEQEAPLFSSITSHLLTAQPWMDDLGAMITQIEEIEQHLTYLKWVSQIEELSDNIQQYLMTNNVPEAASILVTMTELDIKLQESSCTHLLSFVRATVKFWHKILKDKLTSDFEEILAQLHWPFITHTQSQAVGINWPAGAPEIYGTLETLFCQLLKLQASDELLTEQKQLPEKYSLPECPSVILPIQIMLTPLQKRFKYHFRGSRQTNVISKLEFSRGLVMLILEKLASDIPCLLYDDNLFCHLVDEVLLFERELHSVHGYPSTFASCMHILSEETCFQRWLTVERKFALQKMDSMLSSEAVWVSQYKDITDVDEMKVPDCAEVFMTLLLVITDRYKNLPTAPRKLQFLELQKDLVDDFRIRLTQVMKEETRAPLDFRYCAILNAVNYISTVLADWADNVFFLQLQQAALEVFAENNALSKLQLGQLASMESSVFDDMINLLERLKLDMLTRQVDHVFREVKDAAKLYKKERWLSLPSQCEQAVMSLSSSACPLLLTLRDRLLQLEQQLCFSLFRVFWQMLVEKLDMYIYQEIILANHFNEGGAAQLQFDMTRNLFPLFSHYCKRPENYFKHVKEACIILNLNIGSALLLKDVLQSASEHLSATAALNEVGIYKLAQQDVEILLNLRTNWPNTGK", "length": 767, "header": "tr|A0A9J7J556-1|A0A9J7J556_CRIGR Computationally mapped isoform of RAD50-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Rint1 PE=3 SV=1 CANONICAL=A0A8C2MR48-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J9Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR48/entry#A0A9J7J9Z4-1", "sequence": { "sequence": "MTNNVPEAASILVTMTELDIKLQESSCTHLLSFVRATVKFWHKILKDKLTSDFEEILAQLHWPFITHTQSQAVGINWPAGAPEIYGTLETLFCQLLKLQASDELLTEQKQLPEKYSLPECPSVILPIQIMLTPLQKRFKYHFRGSRQTNVISKPEWYLAQVLMWIGSHAHFLDEKIQPILDKAGCAVNARLEFSRGLVMLILEKLASDIPCLLYDDNLFCHLVDEVLLFERELHSVHGYPSTFASCMHILSEETCFQRWLTVERKFALQKMDSMLSSEAVWVSQYKDITDVDEMKVPDCAEVFMTLLLVITDRYKNLPTAPRKLQFLELQKDLVDDFRIRLTQVMKEETRAPLDFRYCAILNAVNYISTVLADWADNVFFLQLQQAALEVFAENNALSKLQLGQLASMESSVFDDMINLLERLKLDMLTRQVDHVFREVKDAAKLYKKERWLSLPSQCEQAVMSLSSSACPLLLTLRDRLLQLEQQLCFSLFRVFWQMLVEKLDMYIYQEIILANHFNEGGAAQLQFDMTRNLFPLFSHYCKRPENYFKHVKEACIILNLNIGSALLLKDVLQSASEHLSATAALNEVGIYKLAQQDVEILLNLRTNWPNTGK", "length": 613, "header": "tr|A0A9J7J9Z4-1|A0A9J7J9Z4_CRIGR Computationally mapped isoform of RAD50-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Rint1 PE=3 SV=1 CANONICAL=A0A8C2MR48-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F5U5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5U5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F5U5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5U5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763529", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763529", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of ER to Golgi vesicle-mediated transport", "id": "GO:0060628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060628", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR48", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR48" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR48", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR48" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR48", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR48" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR48", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR48" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Dsl1/NZR complex", "id": "GO:0070939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070939", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR48", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MR79-1", "uniprot_ac": "A0A8C2MR79", "uniprot_id": "A0A8C2MR79_CRIGR", "mass": { "chemical_mass": 92713.0, "monoisotopic_mass": 92713.0 }, "refseq": { "ac": "XP_003507728", "name": "DEP domain-containing protein 1A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507728" }, "gene_names": [ { "name": "Depdc1", "type": "recommended", "evidence": [ { "id": "A0A8C2MR79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79" } ] }, { "name": "Depdc1", "type": "synonym", "evidence": [ { "id": "XP_003507728", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507728" } ] } ], "protein_names": [ { "name": "DEP domain-containing protein 1A", "type": "recommended", "evidence": [ { "id": "A0A8C2MR79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79/entry#names_and_taxonomy" } ] }, { "name": "DEP domain-containing protein 1A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003507728", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507728" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614413.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003507728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507728" } ] }, { "annotation": "May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR79", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79#function" }, { "database": "UniProtKB", "id": "ARBA00055549", "url": "https://www.uniprot.org/uniprotkb/ARBA00055549#function" }, { "database": "UniProtKB", "id": "A0A9J7JCN9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JCN9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR79", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Depdc1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79", "locus": {} } ], "crossref": [ { "id": "cd04405", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04405", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767779", "url": "https://www.ncbi.nlm.nih.gov/gene/100767779", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767779", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767779", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRRHMRT", "url": "https://omabrowser.org/oma/group/HRRHMRT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MR79", "url": "https://www.orthodb.org/?gene=A0A8C2MR79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MUB7", "url": "https://www.orthodb.org/?gene=A0A8C2MUB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7F911", "url": "https://www.orthodb.org/?gene=A0A9J7F911", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JCN9", "url": "https://www.orthodb.org/?gene=A0A9J7JCN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16206", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16206", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16206:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16206:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00610", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00610", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003507728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507728", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MR79", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MR79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUB7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F911", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F911", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F911-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F911-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JCN9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JCN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JCN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JCN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K2Z7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K2Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDRGAPLGPYRATKLWNEVTTSFRVGMPLRKHRQHLKKYSNCFTAGEAVDWLYDLLRSNSNFGPEVTRQQTVQLLRKFLKNHVIEDIKGRWGSENLDDNNQLFRFPATSPLKTLPQRHTEIRKTSTEYFSKDKDSIFKLRNLSRKTPKKRGLLFSQENTENISHERIINEDQENSADNREISQEDVEEVWRYIIMIYLQTILGVPSIEELINPSQVIPQYIIYNMSNTSKHGVVILQDKSEDLPHWVLSAMKCLANWPKSNDNNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILVVCGYITVSDRTSGIHKIHDDPRSSKIHHLSNLNSFKSTECLLLSLLHKDKSSEELDSTEILQRSDQGSQERCAKTMQIVNFRNRRASANDIMGGSCHNLIGLSNTHVLSSNTKPRCSSLEGIVDMPGNSSKKASSVFHQSFLSKVLNSKQSLVPMTKQKSLFNLHSEENIQQPYCADFKRNPTLTVQNQGELWKGNNNSKQLCRSQSLLLRNSTRQNRYINTPVAEIIMKPNVGQGSTSVRSELGESSPTINKRLCKSTVELSENSLLPAASKLTGTQSLLQPHLERVAINALQLCCLLLPPSNRRKLQLLMCMISRMSQNVDMPKLHEEIGTRSLMIRTFSRCVLCCAEEVDLDELLASRLVSFLMDHHQEILQVPTYLQTAVEKHLDYIRKGHVKNPGYGQVVPLPTYSYCQQISTQEFDEQKISTSQVAIEELLESIVRSKSLSLKERRRKLRQFQKEYPLIYKKRFPTTESEAALLDGKPTIKQPMLSLRNAKFHSLRY", "length": 808, "header": "tr|A0A8C2MR79-1|A0A8C2MR79_CRIGR Isoform 1 of DEP domain-containing protein 1A OS=Cricetulus griseus OX=10029 GN=Depdc1 PE=4 SV=1 CANONICAL=A0A8C2MR79-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MR79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79/entry#A0A8C2MR79-1", "sequence": { "sequence": "MEDRGAPLGPYRATKLWNEVTTSFRVGMPLRKHRQHLKKYSNCFTAGEAVDWLYDLLRSNSNFGPEVTRQQTVQLLRKFLKNHVIEDIKGRWGSENLDDNNQLFRFPATSPLKTLPQRHTEIRKTSTEYFSKDKDSIFKLRNLSRKTPKKRGLLFSQENTENISHERIINEDQENSADNREISQEDVEEVWRYIIMIYLQTILGVPSIEELINPSQVIPQYIIYNMSNTSKHGVVILQDKSEDLPHWVLSAMKCLANWPKSNDNNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILVVCGYITVSDRTSGIHKIHDDPRSSKIHHLSNLNSFKSTECLLLSLLHKDKSSEELDSTEILQRSDQGSQERCAKTMQIVNFRNRRASANDIMGGSCHNLIGLSNTHVLSSNTKPRCSSLEGIVDMPGNSSKKASSVFHQSFLSKVLNSKQSLVPMTKQKSLFNLHSEENIQQPYCADFKRNPTLTVQNQGELWKGNNNSKQLCRSQSLLLRNSTRQNRYINTPVAEIIMKPNVGQGSTSVRSELGESSPTINKRLCKSTVELSENSLLPAASKLTGTQSLLQPHLERVAINALQLCCLLLPPSNRRKLQLLMCMISRMSQNVDMPKLHEEIGTRSLMIRTFSRCVLCCAEEVDLDELLASRLVSFLMDHHQEILQVPTYLQTAVEKHLDYIRKGHVKNPGYGQVVPLPTYSYCQQISTQEFDEQKISTSQVAIEELLESIVRSKSLSLKERRRKLRQFQKEYPLIYKKRFPTTESEAALLDGKPTIKQPMLSLRNAKFHSLRY", "length": 808, "header": "tr|A0A8C2MR79-1|A0A8C2MR79_CRIGR Isoform 1 of DEP domain-containing protein 1A OS=Cricetulus griseus OX=10029 GN=Depdc1 PE=4 SV=1 CANONICAL=A0A8C2MR79-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MUB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79/entry#A0A8C2MUB7-1", "sequence": { "sequence": "MEDRGAPLGPYRATKLWNEVTTSFRVGMPLRKHRQHLKKYSNCFTAGEAVDWLYDLLRSNSNFGPEVTRQQTVQLLRKFLKNHVIEDIKGRWGSENLDDNNQLFRFPATSPLKTLPQRHTEIRKTSTEYFSKDKDSIFKLRNLSRKTPKKRGLLFSQENTENISHERIINEDQENSADNREISQEDVEEVWRYIIMIYLQTILGVPSIEELINPSQVIPQYIIYNMSNTSKHGVVILQDKSEDLPHWVLSAMKCLANWPKSNDNNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILGLLQPHLERVAINALQLCCLLLPPSNRRKLQLLMCMISRMSQNVDMPKLHEEIGTRSLMIRTFSRCVLCCAEEVDLDELLASRLVSFLMDHHQEILQVPTYLQTAVEKHLDYIRKGHVKNPGYGQVVPLPTYSYCQQISTQEFDEQKISTSQVAIEELLESIVRSKSLSLKERRRKLRQFQKEYPLIYKKRFPTTESEAALLDGKPTIKQPMLSLRNAKFHSLRY", "length": 529, "header": "tr|A0A8C2MUB7-1|A0A8C2MR79_CRIGR Computationally mapped isoform of DEP domain-containing protein 1A OS=Cricetulus griseus OX=10029 GN=Depdc1 PE=4 SV=1 CANONICAL=A0A8C2MR79-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F911-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79/entry#A0A9J7F911-1", "sequence": { "sequence": "MPLRKHRQHLKKYSNCFTAGEAVDWLYDLLRSNSNFGPEVTRQQTVQLLRKFLKNHVIEDIKGRWGSENLDDNNQLFRFPATSPLKTLPQRHTEIRKTSTEYFSKDKDSIFKLRNLSRKTPKKRGLLFSQENTENISHERIINEDQENSADNREISQEDVEEVWRYIIMIYLQTILGVPSIEELINPSQVIPQYIIYNMSNTSKHGVVILQDKSEDLPHWVLSAMKCLANWPKSNDNNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILVVCGYITVSDRTSGIHKIHDDPRSSKIHHLSNLNSFKSTECLLLSLLHKDKSSEELDSTEILQRSDQGSQERCAKTMQIVNFRNRRASANDIMGGSCHNLIGLSNTHVLSSNTKPRCSSLEGIVDMPGNSSKKASSVFHQSFLSKVLNSKQSLVPMTKQKSLFNLHSEENIQQPYCADFKRNPTLTVQNQGELWKGNNNSKQLCRSQSLLLRNSTRQNRYINTPVAEIIMKPNVGQGSTSVRSELGESSPTINKRLCKSTVELSENSLLPAASKLTGTQSLLQPHLERVAINALQLCCLLLPPSNRRKLQLLMCMISRMSQNVDMPKLHEEIGTRSLMIRTFSRCVLCCAEEVDLDELLASRLVSFLMDHHQEILQVPTYLQTAVEKHLDYIRKGHVKNPGYGQVVPLPTYSYCQQISTQEFDEQKISTSQVAIEELLESIVRSKSLSLKERRRKLRQFQKEYPLIYKKRFPTTESEAALLDGKPTIKQPMLSLRNAKFHSLRY", "length": 781, "header": "tr|A0A9J7F911-1|A0A8C2MR79_CRIGR Computationally mapped isoform of DEP domain-containing protein 1A OS=Cricetulus griseus OX=10029 GN=Depdc1 PE=4 SV=1 CANONICAL=A0A8C2MR79-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JCN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79/entry#A0A9J7JCN9-1", "sequence": { "sequence": "MEDRGAPLGPYRATKLWNEVTTSFRVGMPLRKHRQHLKKYSNCFTAGEAVDWLYDLLRSNSNFGPEVTRQQTVQLLRKFLKNHVIEDIKGRWGSENLDDNNQLFRFPATSPLKTLPQRHTEIRKTSTEYFSKDKDSIFKLRNLSRKTPKKRGLLFSQENTENISHERIINEDQENSADNREISQEDVEEVWRYIIMIYLQTILGVPSIEELINPSQVIPQYIIYNMSNTSKHGVVILQDKSEDLPHWVLSAMKCLANWPKSNDNNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILVVCGYITVSDRTSGIHKIHDDPRSSKIHHLSNLNSFKSTECLLLSLLHKDKSSEELDSTEILQRSDQGSQERCAKTMQIVNFRNRRASANDIMGGSCHNLIGLSNTHVLSSNTKPRCSSLEGIVDMPGNSSKKASSVFHQSFLSKVLNSKQSLVPMTKQKSLFNLHSEENIQQPYCADFKRNPTLTVQNQGELWKGNNNSKQLCRSQSLLLRNSTRQNRYINTPVAEIIMKPNVGQGSTSVRSELGESSPTINKRLCKSTVELSENSLLPAASKLTGTQSLLQPHLERVAINALQLCCLLLPPSNRRKLQLLMCMISRMSQNVDMPKLHEEIGTRSLMIRTFSRCVLCCAEEVDLDELLASRLVSFLMDHHQEILQVPTYLQTAVEKHLDYIRKGHISTQEFDEQKISTSQVAIEELLESIVRSKSLSLKERRRKLRQFQKEYPLIYKKRFPTTESEAALLDGKPTIKQPMLSLRNAKFHSLRY", "length": 788, "header": "tr|A0A9J7JCN9-1|A0A9J7JCN9_CRIGR Computationally mapped isoform of DEP domain-containing protein 1A OS=Cricetulus griseus OX=10029 GN=Depdc1 PE=4 SV=1 CANONICAL=A0A8C2MR79-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K2Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79/entry#A0A9J7K2Z7-1", "sequence": { "sequence": "MQRGKHERFPATSPLKTLPQRHTEIRKTSTEYFSKDKDSIFKLRNLSRKTPKKRGLLFSQENTENISHERIINEDQENSADNREISQEDVEEVWRYIIMIYLQTILGVPSIEELINPSQVIPQYIIYNMSNTSKHGVVILQDKSEDLPHWVLSAMKCLANWPKSNDNNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILVVCGYITVSDRTSGIHKIHDDPRSSKIHHLSNLNSFKSTECLLLSLLHKDKSSEELDSTEILQRSDQGSQERCAKTMQIVNFRNRRASANDIMGGSCHNLIGLSNTHVLSSNTKPRCSSLEGIVDMPGNSSKKASSVFHQSFLSKVLNSKQSLVPMTKQKSLFNLHSEENIQQPYCADFKRNPTLTVQNQGELWKGNNNSKQLCRSQSLLLRNSTRQNRYINTPVAEIIMKPNVGQGSTSVRSELGESSPTINKRLCKSTVELSENSLLPAASKLTGTQSLLQPHLERVAINALQLCCLLLPPSNRRKLQLLMCMISRMSQNVDMPKLHEEIGTRSLMIRTFSRCVLCCAEEVDLDELLASRLVSFLMDHHQEILQVPTYLQTAVEKHLDYIRKGHVKNPGYGQVVPLPTYSYCQQISTQEFDEQKISTSQVAIEELLESIVRSKSLSLKERRRKLRQFQKEYPLIYKKRFPTTESEAALLDGKPTIKQPMLSLRNAKFHSLRY", "length": 711, "header": "tr|A0A9J7K2Z7-1|A0A8C2MR79_CRIGR Computationally mapped isoform of DEP domain-containing protein 1A OS=Cricetulus griseus OX=10029 GN=Depdc1 PE=4 SV=1 CANONICAL=A0A8C2MR79-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUB7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUB7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767779", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767779", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B5S3-1", "protein_name": "DEP domain-containing protein 1A", "gene_name": "DEPDC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENRSVPPGPYRATKLWNEVTTSFRSGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNNSNFGPEVTRQQTIQLLRKFLKNHVIEDIKGKWGSENLDDNSQLFENTEKMNRDMISEDQENSVDNREINQKDVEEVWRHVVLIYLQTILGVSSLEEVINPKQVIPQYIMYNMTNTSKHGVVILQDKSDDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILVVCGYLTVSDRSSGLHKIQDDPQSSKILHLNSLNSFKSTECLLLSLLHKDKNKEESDTTERLQISDQGFQEKYAKKMQLVNLKYRRASANDIMGGSCHNLIGLSSMHGLCSNIKPRCYSLEGIIDLPGNSSKEVSSVFHQSVLNIEGQNNKHFLESKAKQESSLSLHSEQNIQKPLCVGFKRTSTLTIQDQEELCNGKCKSKQLCRSQSLLLRSSTRRNSYINMPVAEIIMKPNLGRGSTSVQTAMEGELRESSTTINKRLCKSTIELSENSLPPASSVLTGTQSLLQPHLERIAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPQLHDAMGTRSLMIHTFSRCVLRCAEEVDLDELLAARLVSFLMDHHQEILQVPSYLQTTVEEHLDYLRRGHIKNPSDVLIAPLPTYSYCKQISAQEFEEQKVSTSQAAIAELLENIIKNKSLPLKEKRKKLKQFQKEYPLIYQKRFPTSESEAALFDDKPTIKQPMLILRKPKFRSLRY", "length": 759 }, "evidence": [ { "id": "A0A8C2MR79", "url": "https://omabrowser.org/oma/group/A0A8C2MR79/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q2TSI6-1", "protein_name": "DEP domain-containing protein 1A", "gene_name": "DEPDC1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MERRPAAPGPYRATELWNEITRYFRAGMPLRTHRQHFKKHGSCFTASEAADWLHEVLRSSSNFGPEVSRQQTVQLLRKFLKNHVIEDIKGRWGAENLEDNGALYRFPSTSPVKPLPAPCRQNENLQTFSKDRLLKLPHLSRRTLKKHQLLTPLDNVEKTKLDKTAENEEDALCRKEVSQEYVQETWRNIILIHLQTILGLPSLEEVLQPTQIVPEHVIYNMTHTSKHGVVILQNKSEDLPHWVLSAMKCLAYWPRNNDMSQPTYSGFERDVFRTVADYFVNLPEPLLTFEYYELFVNILVMCGFITIPNTCSGKHSVRDETRDPQSSKIPHLNSFKSTECLLLSLLRKEPKEIKEDYEASWKSSSEELADQTQRAKKLQQHKLASKQGSADNLIGGSCQNLSGFRNEQDLSLTFKTRCYSLERIGNTASRVHNKGELDSLRKTNVLSTRNEKQWLPCVSKTDSVLEFGFENTFQKQTDGSKRVSAPILQDRELFKENLKSKQICRSQGLLGSRSSRSCTSINVPIAEITVKPRSQLCGQGRPNTSVATSVGIRTEVSDITVSKRLCRSTIELSECSFTHSYVLTGTQNLLQPHLERIAVEALQICCLLLPPPNRRKMQLLMRMISRISENVDMPQLHDAMSTRSLMIQTFSRCVLCCAEEVDLDELLSTRLVSFLMDHQQEIFKVPTYLQVAVQDHLEYMKVAQCKYPGEEICAILPTYSYCEQITPQEFEEQKVSTSQAAVAELLENIIKDKNLSVKEKKKKLKQFQKEYPLIYQNRFPTTENEAMLFENKPTIKQPMLSLRKPKFRSLRH", "length": 812 }, "evidence": [ { "id": "A0A8C2MR79", "url": "https://omabrowser.org/oma/group/A0A8C2MR79/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZGJ9-1", "protein_name": "DEP domain-containing protein 1A", "gene_name": "Depdc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERQGAPLGPYRATKLWNEVTTSFRVGMPLRKHRQHLKKYSNCFTAVEAVDWLYDLLRSNSNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENLDDNNQLFRFPATSPLKTFPQRHTEIKKTSTEYFSKDRDSIFKLRNLSRKTPKKRGLQFSQENTEKINHERITNEDQENVPENKEISQEDVEDVWRYVTMIYLQTILGVPSIEELINPNQVIPQYIMYNMANTSKHGVVILQNKSEDLPHWVLSAMKCLANWPRCNDTNSLTYVGFERDVFKTIADYFLDLPEPLLTFEYYELFVNILVVCGYITVSDKTSGIHKIQDDPRSSQIHDLSNLNSFKSTECLLLSLLSKDKSNEELDSTERLQRSDQGFQERCTKKMQLVNLRNRRASANDIMGGSCHNLIGLSNTNALSSNIKPRCSSLEGIIDMPVNSSEKKSSVFYLSVLNIEEHSSEQSLAPVPKQKSLLNLHSEEYAQQPHSVGFKRTSALTIEDQEDVCNGKYTSKQLCRSQSLLLRSSTRQNSSINKPVAEIIMKPNVGQGSTSVQSKLGGSITTINKRLCKSTIELSENSLPPAASVLTGTQSLLQPHLERVAINALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDLPKLHEEIGTRSLMINTFSRCVLCCAEEVDLDELLASRLVSFLMDHHQEILQVPTYLQAAVEKHLDYIKKGHVKNHGDGLVVPLPTYSYCKQISAKEFDEQKISTSQAAIAELLENIVRSKSLPLKEKRRKLKQFQKEYPLIYQKRFPTTESEAALFDDKPTIKQPMLNLRNPKLHSLRY", "length": 809 }, "evidence": [ { "id": "A0A8C2MR79", "url": "https://omabrowser.org/oma/group/A0A8C2MR79/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5TB30-5", "protein_name": "DEP domain-containing protein 1A", "gene_name": "DEPDC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNNSNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYPELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKSDDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILVVCGYITVSDRSSGIHKIQDDPQSSKFLHLNNLNSFKSTECLLLSLLHREKNKEESDSTERLQISNPGFQERCAKKMQLVNLRNRRVSANDIMGGSCHNLIGLSNMHDLSSNSKPRCCSLEGIVDVPGNSSKEASSVFHQSFPNIEGQNNKLFLESKPKQEFLLNLHSEENIQKPFSAGFKRTSTLTVQDQEELCNGKCKSKQLCRSQSLLLRSSTRRNSYINTPVAEIIMKPNVGQGSTSVQTAMESELGESSATINKRLCKSTIELSENSLLPASSMLTGTQSLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENPGDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKLKQFQKEYPLIYQKRFPTTESEAALFGDKPTIKQPMLILRKPKFRSLR", "length": 811 }, "evidence": [ { "id": "A0A8C2MR79", "url": "https://omabrowser.org/oma/group/A0A8C2MR79/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CIG0-1", "protein_name": "DEP domain-containing protein 1A", "gene_name": "Depdc1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQGAPLGPYRATKLWNEVTTSFRVGMPLRKHRQHLKKYSNCFTAVEAIDWLYDLLRSNSNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSESLDDNNQLFRFPATSPLKTFPQRHTEIKKTNTEYFSKDKDGIFKLRNLSQKTSKKRGLHFSQENTEKINHERITNEDLEIAPDNQEISQEDVEEVWRYVIMIYLQTILSLPSIEELLNPNQVIPQYIMYNMANTSKHGVVILQDKSDDLPHWVLSAMKCLANWPRSNDTNNLTYVGFERDVFKTIADYFLNLPEPLLTFEYYELFVNILVVCGYITVSDRTSGIHKIQDDPRSSKIHDLSNLNSFKSTECLLLSLLYKDKSNEELDSTKRLQRNDQGFQERCAKKMQLDNLRNRRASANDIMGGSCHNLIGLSNTNALSSNIKPRCSSLEGIVDRPVNSSEKKSSIFYQSVLNIEEQNSKQSLVSAPKQTPLFNLHSDENAQQPHCVGFNRTSALTVQDQEELCNEKYKSKQLCRSQSLLLRSSTRQNSCINKPVAEIIMKPNVGQGSTSELGESSTTINKRLCKSTIELSEKSLPPAASVLTGTQSLLQPHLERVAINALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHEQIGTRSLMINTFSRCVLCCAEEVDLDELLASRLVSFLMDHHQEILQVPTYLQAAVEKHLDYIKKGNVKNHGDGLVVPLPTYSYCKQISAKEFDEQKISTSQAAIAELLENIVRSKSLSLKEKRRKLKQKEYPLIYQKRFPTTESEAALFDDKPTIKQPMLNLRNPKLHSLRY", "length": 804 }, "evidence": [ { "id": "A0A8C2MR79", "url": "https://omabrowser.org/oma/group/A0A8C2MR79/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR79", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR79", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR79", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79" } ], "pmid": "" }, { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR79", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR79", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR79", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR79", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MR79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR79" }, { "id": "PS50186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DEP", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 108, "start_aa": "Phe", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 }, { "start_pos": 162, "end_pos": 164 }, { "start_pos": 225, "end_pos": 227 }, { "start_pos": 228, "end_pos": 230 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 502, "end_pos": 504 }, { "start_pos": 517, "end_pos": 519 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MR91-1", "uniprot_ac": "A0A8C2MR91", "uniprot_id": "A0A8C2MR91_CRIGR", "mass": { "chemical_mass": 42651.0, "monoisotopic_mass": 42651.0 }, "refseq": { "ac": "XP_003503474", "name": "neuropeptide S receptor isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503474" }, "gene_names": [ { "name": "Npsr1", "type": "recommended", "evidence": [ { "id": "A0A8C2MR91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91" } ] }, { "name": "Npsr1", "type": "synonym", "evidence": [ { "id": "XP_003503474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503474" } ] } ], "protein_names": [ { "name": "Neuropeptide S receptor", "type": "recommended", "evidence": [ { "id": "A0A8C2MR91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 154", "type": "synonym", "evidence": [ { "id": "A0A8C2MR91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91/entry#names_and_taxonomy" } ] }, { "name": "neuropeptide S receptor isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003503474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503474" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613970.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003503474", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503474" } ] }, { "annotation": "G-protein coupled receptor for neuropeptide S (NPS). Receptor activation by NPS initiates a G(q)/GNAQ-dependent phospholipase C-activating signaling pathway, resulting in Ca(2+) mobilization from intracellular stores and increased intracellular Ca(2+) levels. In addition to this pathway, NPS binding to its receptor activates cAMP/PKA signal transduction. Finally, both pathways converge to activate ERK1/ERK2 phosphorylation and signaling cascade. Inhibits cell growth in response to NPS binding.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR91", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91#function" }, { "database": "UniProtKB", "id": "ARBA00094235", "url": "https://www.uniprot.org/uniprotkb/ARBA00094235#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR91", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Npsr1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91", "locus": {} } ], "crossref": [ { "id": "cd15197", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15197", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765143", "url": "https://www.ncbi.nlm.nih.gov/gene/100765143", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001817", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001817", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765143", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765143", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NRLCPPF", "url": "https://omabrowser.org/oma/group/NRLCPPF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MR91", "url": "https://www.orthodb.org/?gene=A0A8C2MR91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JFR6", "url": "https://www.orthodb.org/?gene=A0A9J7JFR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24244", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24244", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24244:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24244:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003503474", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503474", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MR91", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MR91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JFR6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JFR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFR6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPANLTEGNSHVNQTVPTLDASPVACTEIVTFTEVLATEEWGSFYSSFKTEQLITLWVLFIFTIVGNSVVLFSTWRRKRKSRMTFFVTQLAITDSFTGLINILTDIIWRFTGDFMAPDLVCRVVRYLQVVVLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQAKVLIGIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISVIYGLVIRTIWIKSKAHETVISNCSDGKLCSRYNRGLISKAKIKAIKYSIVIILAFICCWSPYFLFDMLDNFNLLPDTKERFYASVIIQNLPALNSAINPVIYCIFSSSICFPCKEQRSQDSRMTYRERSERQEMQILSKPEFI", "length": 371, "header": "tr|A0A8C2MR91-1|A0A8C2MR91_CRIGR Isoform 1 of Neuropeptide S receptor OS=Cricetulus griseus OX=10029 GN=Npsr1 PE=3 SV=1 CANONICAL=A0A8C2MR91-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MR91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91/entry#A0A8C2MR91-1", "sequence": { "sequence": "MPANLTEGNSHVNQTVPTLDASPVACTEIVTFTEVLATEEWGSFYSSFKTEQLITLWVLFIFTIVGNSVVLFSTWRRKRKSRMTFFVTQLAITDSFTGLINILTDIIWRFTGDFMAPDLVCRVVRYLQVVVLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQAKVLIGIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISVIYGLVIRTIWIKSKAHETVISNCSDGKLCSRYNRGLISKAKIKAIKYSIVIILAFICCWSPYFLFDMLDNFNLLPDTKERFYASVIIQNLPALNSAINPVIYCIFSSSICFPCKEQRSQDSRMTYRERSERQEMQILSKPEFI", "length": 371, "header": "tr|A0A8C2MR91-1|A0A8C2MR91_CRIGR Isoform 1 of Neuropeptide S receptor OS=Cricetulus griseus OX=10029 GN=Npsr1 PE=3 SV=1 CANONICAL=A0A8C2MR91-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JFR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91/entry#A0A9J7JFR6-1", "sequence": { "sequence": "MPANLTEGNSHVNQTVPTLDASPVACTEIVTFTEVLATEEWGSFYSSFKTEQLITLWVLFIFTIVGNSVVLFSTWRRKRKSRMTFFVTQLAITEKQAKVLIGIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISVIYGLVIRTIWIKSKAHETVISNCSDGKLCSRYNRGLISKAKIKAIKYSIVIILAFICCWSPYFLFDMLDNFNLLPDTKERFYASVIIQNLPALNSAINPVIYCIFSSSICFPCKEQRSQDSRMTYRERSERQEMQILSKPEFI", "length": 305, "header": "tr|A0A9J7JFR6-1|A0A9J7JFR6_CRIGR Computationally mapped isoform of Neuropeptide S receptor isoform X2 OS=Cricetulus griseus OX=10029 GN=Npsr1 PE=4 SV=1 CANONICAL=A0A8C2MR91-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR91", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR91", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765143", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765143", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MJZ0-1", "protein_name": "Neuropeptide S receptor", "gene_name": "NPSR1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPANLTEGSAKSNGTGQALNSPVLCTETVTFTAEVEGEEWGSFYYSFKTEQLITLWVLFVFTIVGNAIVLFSTWRRKRKSRMTFFVTQLAITDSFTGLVNILTDIIWRFTGDFMAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQAKVLIMIAWSLSFLFSIPTLIIFGKRKLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISVIYAIVIRTIWVKSKAYETVISNCSDGKLCTSYNRGLISKAKIKAIKYSIVIILAFICCWSPYFLFDILDNFSLLPNTKERFYASVIIQNLPALNSAINPLIYCVFSNSICFPCREQRSRDSRMTCRERTEKHEMQVLSKPEFM", "length": 370 }, "evidence": [ { "id": "A0A8C2MR91", "url": "https://omabrowser.org/oma/group/A0A8C2MR91/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C0L6-1", "protein_name": "Neuropeptide S receptor", "gene_name": "Npsr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPANLTEGSFHANQTVPMLDSSPVACTEIVTFTEALEAEEWGSFYSSFKTEQLITLWVLFVFTIVGNSVVLFSTWRRKRKSRMTFFVTQLAITDSFTGLINILTDIIWRFTGDFMAPDLVCRIVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGAEKQAKVLIGIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISVIYGLVIRTIWIKSKAHETVISNCSDGELCCSYNRGLISKAKIKAIKYSIVIILAFICCWSPYFLFDMLDNFNLLPDTKERFYASVIIQNLPALNSAINPLIYCIFSGSLCSPCKVQRSQDSRMTYRERSERHEMQILSKPEFI", "length": 372 }, "evidence": [ { "id": "A0A8C2MR91", "url": "https://omabrowser.org/oma/group/A0A8C2MR91/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6W5P4-1", "protein_name": "Neuropeptide S receptor", "gene_name": "NPSR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPANFTEGSFDSSGTGQTLDSSPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLFVFTIVGNSVVLFSTWRRKKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWIKSKTYETVISNCSDGKLCSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSISFPCREQRSQDSRMTFRERTERHEMQILSKPEFI", "length": 371 }, "evidence": [ { "id": "A0A8C2MR91", "url": "https://omabrowser.org/oma/group/A0A8C2MR91/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BZP8-1", "protein_name": "Neuropeptide S receptor", "gene_name": "Npsr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPANLTEGSFHANQTVPMLDSSPVACTEIVTFTEALVAEEWGSFYSSFKTEQLITLWVLFVVTIVGNSVVLFSTCRRKRKSRMTFFVTQLAITDSFTGLINILTDIIWRFTGDFMAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQAKVLIGIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLAIISVIYGLVIRTIWMKSKTHETVISNCSDGKLCCSYNRGLISKAKIKAIKYSIVIILAFICCWSPYFLFDILDNFNVLPDTKERFYASVIIQNLPALNSAINPLIYCIFSSSICSPCKMQRSQDSRMTYRERSERHEMQILSKPEFI", "length": 371 }, "evidence": [ { "id": "A0A8C2MR91", "url": "https://omabrowser.org/oma/group/A0A8C2MR91/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR91", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR91", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR91", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91" } ], "pmid": "" }, { "name": "phospholipase C-activating G protein-coupled receptor signaling pathway", "id": "GO:0007200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007200", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR91", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91" } ], "pmid": "" }, { "name": "positive regulation of release of sequestered calcium ion into cytosol", "id": "GO:0051281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051281", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR91", "url": 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"annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MR91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR91" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 330, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MR99-1", "uniprot_ac": "A0A8C2MR99", "uniprot_id": "A0A8C2MR99_CRIGR", "mass": { "chemical_mass": 49672.0, "monoisotopic_mass": 49672.0 }, "refseq": { "ac": "XP_003505563", "name": "sorting nexin-30 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505563" }, "gene_names": [ { "name": "Snx30", "type": "recommended", "evidence": [ { "id": "A0A8C2MR99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR99" } ] }, { "name": "Snx30", "type": "synonym", "evidence": [ { "id": "XP_003505563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505563" } ] } ], "protein_names": [ { "name": "Sorting nexin-30", "type": "recommended", "evidence": [ { "id": "A0A8C2MR99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR99/entry#names_and_taxonomy" } ] }, { "name": "sorting nexin-30 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003505563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505563" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 285 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614157.1) and transcript sequence (IACG01084501.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003505563.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003505563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505563" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR99", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR99" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Snx30", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR99", "locus": {} } ], "crossref": [ { "id": "cd06860", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06860", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07667", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07667", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772271", "url": "https://www.ncbi.nlm.nih.gov/gene/100772271", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772271", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772271", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MR99", "url": "https://www.orthodb.org/?gene=A0A8C2MR99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45949", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45949", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45949:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45949:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03114", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03114", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003505563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505563", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MR99", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MR99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGPPKALPSTGPHSLRDMPHPLAGSSSEEAMGGDSTPSPDLLMARSFGDKDLILPNGGTPAGTSSPASPSSLLNRLQLDDDIDGETRDLFVTVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNAYKKQGIALLTRVGESVKHVTGGYKLRSRPLEFAAIGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDITEEFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVALRKEERPKVPADVEKCQDRMECFNADLKADMERWQNNKRHDFRQLLVGLADKNIQYYEKCLMAWESIIPLLQEKQETK", "length": 437, "header": "tr|A0A8C2MR99-1|A0A8C2MR99_CRIGR Isoform 1 of Sorting nexin-30 OS=Cricetulus griseus OX=10029 GN=Snx30 PE=3 SV=1 CANONICAL=A0A8C2MR99-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MR99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR99/entry#A0A8C2MR99-1", "sequence": { "sequence": "MAGGPPKALPSTGPHSLRDMPHPLAGSSSEEAMGGDSTPSPDLLMARSFGDKDLILPNGGTPAGTSSPASPSSLLNRLQLDDDIDGETRDLFVTVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNAYKKQGIALLTRVGESVKHVTGGYKLRSRPLEFAAIGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDITEEFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVALRKEERPKVPADVEKCQDRMECFNADLKADMERWQNNKRHDFRQLLVGLADKNIQYYEKCLMAWESIIPLLQEKQETK", "length": 437, "header": "tr|A0A8C2MR99-1|A0A8C2MR99_CRIGR Isoform 1 of Sorting nexin-30 OS=Cricetulus griseus OX=10029 GN=Snx30 PE=3 SV=1 CANONICAL=A0A8C2MR99-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 38, "start_aa": "Thr", "end_pos": 38, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr38", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 61, "start_aa": "Thr", "end_pos": 61, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr61", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR99", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR99" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR99", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR99" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772271", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772271", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MR99", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR99" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003507771", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507771", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MRC0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MRC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZD1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZD1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLAIKRRASSGQRPGPDGERAWDMEKARPQWGNPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYVIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWGFWYLFHSFQDPLPWSVCPLNGNRTGYDEECEKASSTQYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLVVYLCILRGTESTGKVVYFTASMPYCVLIIYLVRGLTLHGATNGLMYMFTPKMEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSIINSSTSIFASIVTFSIYGFKATFNYENCLNKVILLLTNSFDLEDGFLTANNLEEVKDYLASTYPSKYSDVFPHIRNCSLESELNTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGMGSMLGNTAAILTPLTDSKVISSYLPKEAISGLVCLINCAIGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLKRFESDLQAMTGRSLNWYWKAMWAFVSPVLIISLFVFYLSDYILTGTLQYQAWDATQGQLVTKDYPPHALAVIGLLVASSTMCIPLVALGTFIRNRLKRGGSSPVA", "length": 616, "header": "tr|A0A8C2MRC0-1|A0A8C2MRC0_CRIGR Isoform 1 of Transporter OS=Cricetulus griseus OX=10029 GN=LOC100760123 PE=3 SV=1 CANONICAL=A0A8C2MRC0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MRC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRC0/entry#A0A8C2MRC0-1", "sequence": { "sequence": "MRLAIKRRASSGQRPGPDGERAWDMEKARPQWGNPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYVIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWGFWYLFHSFQDPLPWSVCPLNGNRTGYDEECEKASSTQYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLVVYLCILRGTESTGKVVYFTASMPYCVLIIYLVRGLTLHGATNGLMYMFTPKMEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSIINSSTSIFASIVTFSIYGFKATFNYENCLNKVILLLTNSFDLEDGFLTANNLEEVKDYLASTYPSKYSDVFPHIRNCSLESELNTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGMGSMLGNTAAILTPLTDSKVISSYLPKEAISGLVCLINCAIGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLKRFESDLQAMTGRSLNWYWKAMWAFVSPVLIISLFVFYLSDYILTGTLQYQAWDATQGQLVTKDYPPHALAVIGLLVASSTMCIPLVALGTFIRNRLKRGGSSPVA", "length": 616, "header": "tr|A0A8C2MRC0-1|A0A8C2MRC0_CRIGR Isoform 1 of Transporter OS=Cricetulus griseus OX=10029 GN=LOC100760123 PE=3 SV=1 CANONICAL=A0A8C2MRC0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRC0/entry#A0A9J7GZD1-1", "sequence": { "sequence": "MRLAIKRRASSGQRPGPDGERAWDMEKARPQWGNPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYVIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWGFWYLFHSFQDPLPWSVCPLNGNRTGYDEECEKASSTQYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLVVYLCILRGTESTGKMEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSIINSSTSIFASIVTFSIYGFKATFNYENCLNKVILLLTNSFDLEDGFLTANNLEEVKDYLASTYPSKYSDVFPHIRNCSLESELNTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGMGSMLGNTAAILTPLTDSKVISSYLPKEAISGLVCLINCAIGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLKRFESDLQAMTGRSLNWYWKAMWAFVSPVLIISLFVFYLSDYILTGTLQYQAWDATQGQLVTKDYPPHALAVIGLLVASSTMCIPLVALGTFIRNRLKRGGSSPVA", "length": 579, "header": "tr|A0A9J7GZD1-1|A0A9J7GZD1_CRIGR Computationally mapped isoform of Transporter OS=Cricetulus griseus OX=10029 GN=LOC100760123 PE=3 SV=1 CANONICAL=A0A8C2MRC0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRC0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRC0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRC0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRC0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760123", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760123", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z8J3-1", "protein_name": "Transporter", "gene_name": "SLC6A20", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEKARPLWDNPLQFVFACISYAVGLGNVWRFPYLCQMYGGGGFLIPYIIMLIVEGMPLLYLELAVGQRMRKGSIGAWKIISPYLCGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWATCPLNSNRTGYEEECEKTSSTQYFWYRQTLNISPSLETSGTVQWEQALCLILAWLVVYLCILRGTASTGKVVYVTASLPYCVLIIYLIRGLTLHGAVNGLIYMFTPKLEQLSNPKTWISAATQIFFSLGLGFGSLIAFASYNDPSNNCERHAIIVSLINSTTSIFASIVTFSIYGFKATFNYESCINKVILLLMNTFDLEEGSLTADNLSEMKDYLMAAHPQEYAQLSPQLKNCSLEAELDTAVQGTGLAFIVYSEAIKNMEVSQLYSVLYFAMLLMLGIGSMLGNTAAILTPLTDSKAITSRFSKEVISGFVCFINCIIGLIFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYIYGLRRFEKDLQTMIGRKLNWYWKAMWAFASPLLIISLFIFYLSDYILTGTLQYQAWDGTQGQLVTRDYPSYALAVIGLLVASSTMCIPLGALLTFIRKRLKRERVSTVA", "length": 592 }, "evidence": [ { "id": "A0A8C2MRC0", "url": "https://omabrowser.org/oma/group/A0A8C2MRC0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q64093-1", "protein_name": "Sodium- and chloride-dependent transporter XTRP3", "gene_name": "Slc6a20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLAIKRRASRGQRPGPDEKRARDMEKARPQWGNPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYLIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWGFWYLFHSFQDPLPWSVCPLNSNRTGYDEECEKASSTQYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLMVYLCILRGTESTGKVVYFTALMPYCVLIIYLVRGLTLHGATNGLMYMFTPKIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNDCQKHAVIVSVINSSTSIFASIVTFSIYGFKATFNYENCLNKVILLLTNSFDLEDGFLTASNLEEVKDYLASTYPNKYSEVFPHIRNCSLESELNTAVQGTGLAFIVYAEAIKNMEVSQLWSVLYFFMLLMLGMGSMLGNTAAILTPLTDSKVISSYLPKEAISGLVCLINCAVGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLRRFESDLRAMTGRPLNWYWKAMWAFVSPLLIIGLFIFYLSDYILTGTLQYQAWDATQGQLVTKDYPPHALAVIGLLVASSTMCIPLVALGTFIRNRLKRGGSSPVA", "length": 616 }, "evidence": [ { "id": "A0A8C2MRC0", "url": "https://omabrowser.org/oma/group/A0A8C2MRC0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VDB9-1", "protein_name": "Sodium- and chloride-dependent transporter XTRP3A", "gene_name": "Slc6a20a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKARPQWGHPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWGFWYLFHSFQDPLPWSVCPLNSNHTGYDEECEKASSTQYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLMVYLCILRGTESTGKVVYFTASMPYCVLIIYLVRGLTLHGATNGLMYMFTPKMEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSIINSSTSIFASIVTFSIYGFKATFNYENCLNKVILLLTNSFDLEDGFLTVSNLEEVKNYLASTYPNKYSEVFPHIRNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKVISSYLPKEAISGLVCLINCAVGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLKRFESDLRAMTGRTLSWYWKVMWAFVSPLLIVGLFIFYLSDYILTGTLQYQAWDATQGQLVTKDYPPHALAVIGLLVASSTMCIPLVALGTFIRNRLKRGGSAPVA", "length": 592 }, "evidence": [ { "id": "A0A8C2MRC0", "url": "https://omabrowser.org/oma/group/A0A8C2MRC0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NP91-1", "protein_name": "Sodium- and chloride-dependent transporter XTRP3", "gene_name": "SLC6A20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKARPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSVCPLNGNHTGYDEECEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCLLLAWLVVYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTLHGATNGLMYMFTPKIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSKYSEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVSLFVFYLSDYILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIPLAALGTFVQRRLKRGDADPVA", "length": 592 }, "evidence": [ { "id": "A0A8C2MRC0", "url": "https://omabrowser.org/oma/group/A0A8C2MRC0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "L-proline transmembrane transporter activity", "id": "GO:0015193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015193", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRC0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRC0" } ], "pmid": "" }, { "name": "proline:sodium symporter activity", "id": "GO:0005298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005298", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRC0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRC0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRC0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRC0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "L-proline import across plasma membrane", "id": "GO:1904271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904271", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRC0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRC0" } ], "pmid": "" }, { "name": "glycine import across plasma membrane", "id": "GO:1903804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903804", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRC0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRC0" } ], "pmid": "" }, { "name": "glycine transport", "id": "GO:0015816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015816", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRC0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRC0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRC0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 179, "end_pos": 181 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 381, "end_pos": 383 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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] }, { "uniprot_canonical_ac": "A0A8C2MRF1-1", "uniprot_ac": "A0A8C2MRF1", "uniprot_id": "A0A8C2MRF1_CRIGR", "mass": { "chemical_mass": 47530.0, "monoisotopic_mass": 47530.0 }, "refseq": { "ac": "XP_003504492", "name": "homeobox protein PKNOX1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504492" }, "gene_names": [ { "name": "Pknox1", "type": "recommended", "evidence": [ { "id": "A0A8C2MRF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRF1" } ] }, { "name": "Pknox1", "type": "synonym", "evidence": [ { "id": "XP_003504492", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504492" } ] } ], "protein_names": [ { "name": "Homeobox protein PKNOX1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2MRF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRF1/entry#names_and_taxonomy" } ] }, { "name": "homeobox protein PKNOX1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003504492", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504492" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614068.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504492", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504492" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRF1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pknox1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRF1", "locus": {} } ], "crossref": [ { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761855", "url": "https://www.ncbi.nlm.nih.gov/gene/100761855", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761855", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761855", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QHVTMPD", "url": "https://omabrowser.org/oma/group/QHVTMPD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MRF1", "url": "https://www.orthodb.org/?gene=A0A8C2MRF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11850", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11850", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504492", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504492", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MRF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMATQTLSIDSYQDGQQMQVVTELKTEQDPNCSDPDAEGVSPPPIESQTPMDADKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKDGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTLSPQGIVVPASALQQGNVTMATVAGGTVYQPVTVVTPQGQVVTQALSPGTIRIQNSQLQLQLNQDLSILHQEDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKPAQNRPVQRFWPDSLASGVAQATSSELAMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEDDGGTLGPTHISGLVLENSDSLQ", "length": 436, "header": "tr|A0A8C2MRF1-1|A0A8C2MRF1_CRIGR Isoform 1 of Homeobox protein PKNOX1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pknox1 PE=3 SV=1 CANONICAL=A0A8C2MRF1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MRF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRF1/entry#A0A8C2MRF1-1", "sequence": { "sequence": "MMATQTLSIDSYQDGQQMQVVTELKTEQDPNCSDPDAEGVSPPPIESQTPMDADKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKDGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTLSPQGIVVPASALQQGNVTMATVAGGTVYQPVTVVTPQGQVVTQALSPGTIRIQNSQLQLQLNQDLSILHQEDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKPAQNRPVQRFWPDSLASGVAQATSSELAMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEDDGGTLGPTHISGLVLENSDSLQ", "length": 436, "header": "tr|A0A8C2MRF1-1|A0A8C2MRF1_CRIGR Isoform 1 of Homeobox protein PKNOX1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pknox1 PE=3 SV=1 CANONICAL=A0A8C2MRF1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRF1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRF1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761855", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761855", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BYI1-1", "protein_name": "PBX/knotted 1 homeobox 1", "gene_name": "PKNOX1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMATQTLSIDNYQDGQPMQVVTELKTEQDPNCSETDAEGVSPAPVESQTPMDADKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKEGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQMPSAIAGTLSPQGIMVPASALQQGNVTMATVAGGTVYQPVTVVTPQGQVVTQALSPGTIRIQNSQLQLQLNQDLGILHQDDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKTAQNRPVQRFWPDSIASGVAQQQSNELTMSDGAVVTITAPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSGEDDGGDLSTTNISGLVLDNSDSLQ", "length": 436 }, "evidence": [ { "id": "A0A8C2MRF1", "url": "https://omabrowser.org/oma/group/A0A8C2MRF1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O70477-1", "protein_name": "Homeobox protein PKNOX1", "gene_name": "Pknox1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMATQTLSIDSYQDGQQMQVVTELKTEQDPNCSDPDAEGVSPPPIESQTPMDADKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKDGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTLSPQGIVVPASALQQGNVTMATVAGGTVYQPVTVVTPQGQVVTQALSPGTIRIQNSQLQLQLNQDLSILHQEDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKPAQNRPVQRFWPDSLASGVAQATPSELAMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEDEGGALAPTHISGLVLENSDSLQ", "length": 436 }, "evidence": [ { "id": "A0A8C2MRF1", "url": "https://omabrowser.org/oma/group/A0A8C2MRF1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P55347-1", "protein_name": "Homeobox protein PKNOX1", "gene_name": "PKNOX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMATQTLSIDSYQDGQQMQVVTELKTEQDPNCSEPDAEGVSPPPVESQTPMDVDKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKEGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTISPQGIVVPASALQQGNVAMATVAGGTVYQPVTVVTPQGQVVTQTLSPGTIRIQNSQLQLQLNQDLSILHQDDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKTAQNRPVQRFWPDSIASGVAQPPPSELTMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEEDAGALAPAHISGLVLENSDSLQ", "length": 436 }, "evidence": [ { "id": "A0A8C2MRF1", "url": "https://omabrowser.org/oma/group/A0A8C2MRF1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2HJ84-1", "protein_name": "Homeobox protein PKNOX1", "gene_name": "PKNOX1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMATQTLSIDSYPDGQQMQVVTELKTEQDPNCSEPDVEGVSPPPVGSQTPMDADKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKEGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTLSPQGIVVPASALQQGNVTMATVAGGTVYQPVTVVTPQGQVVTQALSPGTIRIQNSQLQLQLNQDLSILHQDDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKTAQNRPVQRFWPDSIASGAAQPAASELTVSEGAVVTITAPVSMNVDSLQSLSSDGATLAVQQVMMAEQSEDDSVDSTGDGGAALAPGHLGGLVLENSDSLQ", "length": 436 }, "evidence": [ { "id": "A0A8C2MRF1", "url": "https://omabrowser.org/oma/group/A0A8C2MRF1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5BJP1-1", "protein_name": "PBX/knotted 1 homeobox 1", "gene_name": "Pknox1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMATQTLSIDSYQDGQQMQVVTELKTEQDPNCSDPDAEGVSPPPIESQTPMDADKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKDGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTLSPQGIVVPASALQQGNVTMATVAGGTVYQPVTVVTPQGQVVTQALSPGTIRIQNSQLQLQLNQDLSILHQEDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKPAQNRPVQRFWPDSLASGVAQATPGELAMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEDEGGALAPTHISGLVLENSDSLQ", "length": 436 }, "evidence": [ { "id": "A0A8C2MRF1", "url": "https://omabrowser.org/oma/group/A0A8C2MRF1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRF1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRF1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRF1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRF1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRF1" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRF1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MRF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRF1" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 257, "end_pos": 320, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 31, "end_pos": 33 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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}, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MRG1-1", "uniprot_ac": "A0A8C2MRG1", "uniprot_id": "A0A8C2MRG1_CRIGR", "mass": { "chemical_mass": 45652.0, "monoisotopic_mass": 45652.0 }, "refseq": { "ac": "XP_027240584", "name": "single Ig IL-1-related receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240584" }, "gene_names": [ { "name": "Sigirr", "type": "recommended", "evidence": [ { "id": "A0A8C2MRG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG1" } ] }, { "name": "Sigirr", "type": "synonym", "evidence": [ { "id": "XP_027240584", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240584" } ] } ], "protein_names": [ { "name": "Single Ig IL-1-related receptor", "type": "synonym", "evidence": [ { "id": "A0A8C2MRG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG1/entry#names_and_taxonomy" } ] }, { "name": "single Ig IL-1-related receptor", "type": "synonym", "evidence": [ { "id": "XP_027240584", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240584" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615649.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027240584", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240584" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sigirr", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG1", "locus": {} } ], "crossref": [ { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758695", "url": "https://www.ncbi.nlm.nih.gov/gene/100758695", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758695", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758695", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WCTNNFR", "url": "https://omabrowser.org/oma/group/WCTNNFR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MRG1", "url": "https://www.orthodb.org/?gene=A0A8C2MRG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11890", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11890:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01582", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01582", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027240584", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240584", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MRG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGVCDRALHFLSPPEDQALGPALGSAVALNCTAWVVSRPQCPQPSVQWLKDGLPLGNGSHFSLHQDFWVSANFSRVVSSVLVLNLTNAEDYGSFTCSVWNVSSHSFTLWKAGPAGHVVAVLASLLVLLVLLLVALLYVKCRLNVLLWYQDAYGEVEMNDGKLYDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLEDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLGRAWCSQSFREGLCRLLELTRRPIFITFEGQRREPIHPALRLLRQHRHLVTLLLWKPGSVAPSSDFWKELQLALPRKVQYRPVEGDPQTRLQDDKDPMLIVRGRAAQGRAMELDPDPEGDLGVRGPVFGEPPTPLHSSRVSEGEGHGSEMDVSDLGSRNYSARTDFYCLVSEDDV", "length": 407, "header": "tr|A0A8C2MRG1-1|A0A8C2MRG1_CRIGR Isoform 1 of Single Ig IL-1-related receptor OS=Cricetulus griseus OX=10029 GN=Sigirr PE=3 SV=1 CANONICAL=A0A8C2MRG1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MRG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG1/entry#A0A8C2MRG1-1", "sequence": { "sequence": "MAGVCDRALHFLSPPEDQALGPALGSAVALNCTAWVVSRPQCPQPSVQWLKDGLPLGNGSHFSLHQDFWVSANFSRVVSSVLVLNLTNAEDYGSFTCSVWNVSSHSFTLWKAGPAGHVVAVLASLLVLLVLLLVALLYVKCRLNVLLWYQDAYGEVEMNDGKLYDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLEDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLGRAWCSQSFREGLCRLLELTRRPIFITFEGQRREPIHPALRLLRQHRHLVTLLLWKPGSVAPSSDFWKELQLALPRKVQYRPVEGDPQTRLQDDKDPMLIVRGRAAQGRAMELDPDPEGDLGVRGPVFGEPPTPLHSSRVSEGEGHGSEMDVSDLGSRNYSARTDFYCLVSEDDV", "length": 407, "header": "tr|A0A8C2MRG1-1|A0A8C2MRG1_CRIGR Isoform 1 of Single Ig IL-1-related receptor OS=Cricetulus griseus OX=10029 GN=Sigirr PE=3 SV=1 CANONICAL=A0A8C2MRG1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758695", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758695", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LD75-1", "protein_name": "Single Ig and TIR domain containing", "gene_name": "SIGIRR", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGVCDRALDFLSPSGNQVLGPALGSAVTLNCTASVVSGPHCPLPSVQWLKDGLPLGNGSHHDLHEDSWVKANWSEVLVSSVLGVNLTSTEDFGTFTCSIQNVSSSSFILRRAGLAGHVATVLASVMVLLALLLAALLYVKCRLNVLLWYQDKYGEVEMNDGKLYDAYVSYSDSPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLVVVLSDAFLGRAWCSHSFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRPGSVTPSSDFWKELQLALPRKVQYRAMEGDPQTRLQDDKDPMLIVGGRGPEGRTLDPELDPDPEGDLGVRGPVFGEPAVPSHASGVSLGEGRGSEVDVSDLGSRNYSARTDFYCLVSEDDV", "length": 410 }, "evidence": [ { "id": "A0A8C2MRG1", "url": "https://omabrowser.org/oma/group/A0A8C2MRG1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q4V892-1", "protein_name": "Single Ig IL-1-related receptor", "gene_name": "Sigirr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGVCDRVPNFLSPSEDQALGPALGSAVALNCTAWVFSRPQCPQPSVQWLKDGLALGNGSHFSLHQDFWVSDNFSEIVSSVLVFNLTKAEDYGTFTCSAWNVSSHSFTLWRAGPAGHVAAVLASLLVLVVLLLVALLYVKCRLNVLLWYQDTYGEVEMNDGKLYDAYVSYSDRPEDRKFVNFILKPQLERRRGYKLFLEDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLRRPWCSQSFREGLCRLLELTRRPIFITFEGQRREPIHPALRLLRQHRHLVTLLLWKPGSVTPSSDFWKELQLALPRKVQYRPVEGDPQTRLQDDKDPMLIVRGRAAQGRAMESELDPDPEGDLGVRGPVFGEPPTPLHESKVSIGEGHASEMDVSDLGSRNYSARTDFYCLVSEDDV", "length": 409 }, "evidence": [ { "id": "A0A8C2MRG1", "url": "https://omabrowser.org/oma/group/A0A8C2MRG1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IA17-1", "protein_name": "Single Ig IL-1-related receptor", "gene_name": "SIGIRR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQRAGPTSHVAAVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLSRAWCSHSFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRPGSVTPSSDFWKEVQLALPRKVQYRPVEGDPQTQLQDDKDPMLILRGRVPEGRALDSEVDPDPEGDLGVRGPVFGEPSAPPHTSGVSLGESRSSEVDVSDLGSRNYSARTDFYCLVSKDDM", "length": 410 }, "evidence": [ { "id": "A0A8C2MRG1", "url": "https://omabrowser.org/oma/group/A0A8C2MRG1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JLZ8-1", "protein_name": "Single Ig IL-1-related receptor", "gene_name": "Sigirr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGVCDMAPNFLSPSEDQALGLALGREVALNCTAWVFSRPQCPQPSVQWLKDGLALGNGSHFSLHEDFWVSANFSEIVSSVLVLNLTNAEDYGTFTCSVWNVSSHSFTLWRAGPAGHVAAVLASLLVLVVLLLVALLYVKCRLNMLLWYQDTYGEVEMNDGKLYDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLEDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLSRPWCSQSFREGLCRLLELTRRPIFITFEGQRREPIHPALRLLRQHRHLVTLVLWKPGSVTPSSDFWKELQLALPRKVQYRPVEGDPQTRLQDDKDPMLIVRGRAAQGRGMESELDPDPEGDLGVRGPVFGEPPTPLQETRICIGESHGSEMDVSDLGSRNYSARTDFYCLVSEDDV", "length": 409 }, "evidence": [ { "id": "A0A8C2MRG1", "url": "https://omabrowser.org/oma/group/A0A8C2MRG1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of interleukin-1-mediated signaling pathway", "id": "GO:2000660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000660", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG1" } ], "pmid": "" }, { "name": "signal 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"" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": 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"homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 391, "end_pos": 393 }, { "start_pos": 58, "end_pos": 60 }, { "start_pos": 73, "end_pos": 75 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MRG5-1", "uniprot_ac": "A0A8C2MRG5", "uniprot_id": "A0A8C2MRG5_CRIGR", "mass": { "chemical_mass": 65295.0, "monoisotopic_mass": 65295.0 }, "refseq": { "ac": "XP_027259330", "name": "pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259330" }, "gene_names": [ { "name": "Pdp1", "type": 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dehydrogenase phosphatase catalytic subunit 1", "type": "synonym", "evidence": [ { "id": "A0A8C2MRG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5/entry#names_and_taxonomy" } ] }, { "name": "pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_027259330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259330" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027259330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259330" } ] }, { "annotation": "Mitochondrial enzyme that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex (PDC), thereby stimulating the conversion of pyruvate into acetyl-CoA.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FHN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FHN4#function" }, { "database": "UniProtKB", "id": "ARBA00043921", "url": "https://www.uniprot.org/uniprotkb/ARBA00043921#function" }, { "database": "UniProtKB", "id": "A0A9J7FJU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJU9#function" }, { "database": "UniProtKB", "id": "A0A8C2MRG5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5#function" }, { "database": "UniProtKB", "id": "A0A8C2MX60", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX60#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRG5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pdp1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5", "locus": {} } ], "crossref": [ { "id": "cd00143", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00143", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761381", "url": "https://www.ncbi.nlm.nih.gov/gene/100761381", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761381", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761381", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MRG5", "url": "https://www.orthodb.org/?gene=A0A8C2MRG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832:SF627", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832:SF627", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00481", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00481", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027259330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259330", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12669", "url": "https://www.rhea-db.org/rhea/12669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MRG5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MRG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MX60", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MX60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FHN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FHN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FHN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FHN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FJU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FJU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERPCRACPGSCSPPPGAVMPPGRQGIPVRTSSLPLFSDAMPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSPTYIPQNRLRYTPHPAYATFCRPRENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESADIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHQQQPIAVGGYKVTLGQMHGLLTERRAKMSSVFEDQNAATHLIRHAVGNNEFGAVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQEQ", "length": 578, "header": "tr|A0A8C2MRG5-1|A0A8C2MRG5_CRIGR Isoform 1 of [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial OS=Cricetulus griseus OX=10029 GN=Pdp1 PE=3 SV=1 CANONICAL=A0A8C2MRG5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MRG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5/entry#A0A8C2MRG5-1", "sequence": { "sequence": "MERPCRACPGSCSPPPGAVMPPGRQGIPVRTSSLPLFSDAMPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSPTYIPQNRLRYTPHPAYATFCRPRENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESADIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHQQQPIAVGGYKVTLGQMHGLLTERRAKMSSVFEDQNAATHLIRHAVGNNEFGAVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQEQ", "length": 578, "header": "tr|A0A8C2MRG5-1|A0A8C2MRG5_CRIGR Isoform 1 of [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial OS=Cricetulus griseus OX=10029 GN=Pdp1 PE=3 SV=1 CANONICAL=A0A8C2MRG5-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MX60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5/entry#A0A8C2MX60-1", "sequence": { "sequence": "MCVCPGPRRIGIPVRTSSLPLFSDAMPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSPTYIPQNRLRYTPHPAYATFCRPRENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESADIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHQQQPIAVGGYKVTLGQMHGLLTERRAKMSSVFEDQNAATHLIRHAVGNNEFGAVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQEQ", "length": 563, "header": "tr|A0A8C2MX60-1|A0A8C2MX60_CRIGR Computationally mapped isoform of [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial OS=Cricetulus griseus OX=10029 GN=Pdp1 PE=3 SV=1 CANONICAL=A0A8C2MRG5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FHN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5/entry#A0A9J7FHN4-1", "sequence": { "sequence": "MPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSPTYIPQNRLRYTPHPAYATFCRPRENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESADIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHQQQPIAVGGYKVTLGQMHGLLTERRAKMSSVFEDQNAATHLIRHAVGNNEFGAVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQEQ", "length": 538, "header": "tr|A0A9J7FHN4-1|A0A8C2MRG5_CRIGR Computationally mapped isoform of [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial OS=Cricetulus griseus OX=10029 GN=Pdp1 PE=3 SV=1 CANONICAL=A0A8C2MRG5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FJU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5/entry#A0A9J7FJU9-1", "sequence": { "sequence": "MLSAPCCDDRRMCVCPGPRRIGIPVRTSSLPLFSDAMPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSPTYIPQNRLRYTPHPAYATFCRPRENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESADIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHQQQPIAVGGYKVTLGQMHGLLTERRAKMSSVFEDQNAATHLIRHAVGNNEFGAVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQEQ", "length": 574, "header": "tr|A0A9J7FJU9-1|A0A8C2MRG5_CRIGR Computationally mapped isoform of [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial OS=Cricetulus griseus OX=10029 GN=Pdp1 PE=3 SV=1 CANONICAL=A0A8C2MRG5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FHN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FHN4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FHN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FHN4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761381", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761381", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity", "id": "GO:0004741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004741", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRG5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRG5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRG5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of pyruvate decarboxylation to acetyl-CoA", "id": "GO:0140176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140176", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRG5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12669", "name": "", "equation": "O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + H2O = L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8C2MRG5-1", "A0A9J7FNL9-1", "A0A9J7GIG0-1" ], "evidence": [ { "id": "12669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8C2MRG5", "gene_name": "Pdp1", "activity": [ { "ec_number": "3.1.3.43", "activity": "O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + H2O = L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + phosphate.", "evidence": [ { "id": "A0A8C2MRG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5" } ] }, { "ec_number": "3.1.3.43", "activity": "", "evidence": [ { "id": "A0A8C2MRG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5" } ] } ] }, { "uniprot_ac": "A0A9J7FNL9", "gene_name": "Pdp2", "activity": [ { "ec_number": "3.1.3.43", "activity": "O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + H2O = L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + phosphate.", "evidence": [ { "id": "A0A9J7FNL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNL9" } ] }, { "ec_number": "3.1.3.43", "activity": "", "evidence": [ { "id": "A0A9J7FNL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNL9" } ] } ] }, { "uniprot_ac": "A0A9J7GIG0", "gene_name": "LOC100752399", "activity": [ { "ec_number": "3.1.3.43", "activity": "O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + H2O = L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + phosphate.", "evidence": [ { "id": "A0A9J7GIG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIG0" } ] }, { "ec_number": "3.1.3.43", "activity": "", "evidence": [ { "id": "A0A9J7GIG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIG0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MRG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRG5" }, { "id": "PS51746", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51746" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPM-type phosphatase", "eco_id": "ECO_0000259", "start_pos": 149, "end_pos": 565, "start_aa": "Ile", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.43", "ec_name": "O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + H2O = L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + phosphate.", "evidence": [ { "id": "3.1.3.43", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.43" }, { "id": "3.1.3.43", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.43" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027272015", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272015" } ] }, { "annotation": "Small GTPase-like component of the intraflagellar transport (IFT) complex B.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRI0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRI0#function" }, { "database": "UniProtKB", "id": "ARBA00037285", "url": "https://www.uniprot.org/uniprotkb/ARBA00037285#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRI0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRI0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ift22", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRI0", "locus": {} } ], "crossref": [ { "id": "100768415", "url": "https://www.ncbi.nlm.nih.gov/gene/100768415", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768415", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768415", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MRI0", "url": "https://www.orthodb.org/?gene=A0A8C2MRI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24073", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24073", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08477", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08477", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027272015", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272015", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MRI0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MRI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKAKILFVGPCESGKTVLANFLTESSDITEYNPTQGVRILEFENPHVTSNNKGTGCEFELWDCGGDSKFESCWPALMKDAHGVVIVFNADIPSHLKEIEMWYSCFVQQQFLQDSHCMLVAHHKPGSGGDKGSLALSPPLNKLKLVHSNLEEDPEEVRVEFIKYLKSIISSLSESRDREEMLIIT", "length": 185, "header": "tr|A0A8C2MRI0-1|A0A8C2MRI0_CRIGR Isoform 1 of Intraflagellar transport protein 22 homolog OS=Cricetulus griseus OX=10029 GN=Ift22 PE=3 SV=1 CANONICAL=A0A8C2MRI0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MRI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRI0/entry#A0A8C2MRI0-1", "sequence": { "sequence": "MLKAKILFVGPCESGKTVLANFLTESSDITEYNPTQGVRILEFENPHVTSNNKGTGCEFELWDCGGDSKFESCWPALMKDAHGVVIVFNADIPSHLKEIEMWYSCFVQQQFLQDSHCMLVAHHKPGSGGDKGSLALSPPLNKLKLVHSNLEEDPEEVRVEFIKYLKSIISSLSESRDREEMLIIT", "length": 185, "header": "tr|A0A8C2MRI0-1|A0A8C2MRI0_CRIGR Isoform 1 of Intraflagellar transport protein 22 homolog OS=Cricetulus griseus OX=10029 GN=Ift22 PE=3 SV=1 CANONICAL=A0A8C2MRI0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRI0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRI0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"database": "UniProtKB", "id": "A0A8C2MRI0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRI0" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRI0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRI0" } ], "pmid": "" }, { "name": "intraciliary transport particle A", "id": "GO:0030991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030991", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRI0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRI0" } ], "pmid": "" }, { "name": "intraciliary transport particle B", "id": "GO:0030992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030992", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRI0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRI0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MRK5-1", "uniprot_ac": "A0A8C2MRK5", "uniprot_id": "A0A8C2MRK5_CRIGR", "mass": { "chemical_mass": 205657.0, "monoisotopic_mass": 205657.0 }, "refseq": { "ac": "XP_027252045", "name": "plexin-B2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252045" }, "gene_names": [ { "name": "Plxnb2", "type": "recommended", "evidence": [ { "id": "A0A8C2MRK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRK5" } ] }, { "name": 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REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027252045", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252045" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRK5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRK5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Plxnb2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRK5", "locus": {} } ], "crossref": [ { "id": "cd01179", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01179", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01180", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01180", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12792", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12792", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754620", "url": "https://www.ncbi.nlm.nih.gov/gene/100754620", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013548", "url": 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"MAVSLWALTFLGLAGLGLNLRSRKPESFRSDTELNHLVVDEASGVVYVGAVNALYQLSADLHLQQHVVTGPAMDNKKCTPPIEASQCHEAVLTDNVNQLLLLDPPGKRLVECGSLFKGICALRALSNISVRLFYEDGSGEKSFVASNDERVATVGLVSSTRPDGERVLFVGKGNGPHDNGIIVSTRLLDRAEGREAFEAYSDHTTFKAGYLSTNTQQFIAAFEDGRYVFFIFNQQDKHPARNRTLLARMCKDDPSYYSYVEMDLQCRDPSDPQGPFFGTCLAASVATPGAGRALYAVFSRDGRSSGGPGAGLCVFPLDEVNAKMEASRNNCYTGIRETGRETFYKPFHGDIQCGGHVQGAIESFPCGSEHLPYPLGSRDGLITTALLYRGGLNLTAVTVTAENGHIVAFLGTSDGRILKVYLAPDGTSAEYGSILVDINKKIKQDLALSGNLSSLYAMTHDKVFRLPVQECLSYLTCAQCRDSQDPYCGWCVVEGRCTRKAECSRAEETGHWLWSRSKSCVAITDANPQNMSRRAPGQVRLSVSPLPTLTQEDELLCLFGEPPPRSAQVEGDAIICDPPSSIPSTPPGQDHVAVSIQLLFKRGSVFLTSHQYPFYDCREAMSLVENLPCISCASNRWMCQWDLLYHECREASPNPEDGIIRAHMEVNCPQFLDPSPSVIPMNHETEVTFQGKNLDTGKVSSLYVGSDLLKFKATVTMQESGAFSFKTPKLSHDTNETLPLHLYVKSFDKKIDSKLQVTLYNCSFGRSDCSLCLAADPAYRCVWCRGQNRCVYEALCSNVTSECPPPVITRIQPETGPLGGGIRVTIHGSNLGVTADDVKKITVAGQNCAFEPKWYSVSTRIVCAIEAAETPFTGGIEVDVNGKLGHSPPHVQFTYQQPQPLSVEPRQGPQAGGTTLTINGTHLDTGSKEDVRVTLNDVPCEVTKFGAQLQCVTGPQLAPGQMVLEISYGGSRVPSSGVSFTYCENPVLRAFEPLRSFVSGGRSINVTGQGFSLIQKFAMVVIAEPLRSWRRRREAESLEPMTVTGTEYVFYNDTKVVFLSPAVPEEPEAYNLTALIQMDGHRALLRTEAGAFEYVADPTFENFTGGVKKQVNKLIHARGTNLNKAMTLEEAEAFVGAERCIMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSLILPLVMVPMVFIIAVSIYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPTLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPESRRPIVEQALYQFSNLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMRTLFLELMEQYVVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVIIQDEGVEAIPVKVLNCDTISQVKEKIIDQVYRTQPCSCWPKPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRINTLMHYNVRDGATLILSKVGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEIYLTRLLSVKGTLQQFVDNFFQSVLAPGNAVPPAVKYFFDFLDEQAEKHDIRDEDTIHIWKTNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL", "length": 1841, "header": "tr|A0A8C2MRK5-1|A0A8C2MRK5_CRIGR Isoform 1 of Plexin-B2 OS=Cricetulus griseus OX=10029 GN=Plxnb2 PE=3 SV=1 CANONICAL=A0A8C2MRK5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 287, "start_aa": "Thr", "end_pos": 287, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr287", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"A0A8C2MRK5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRK5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of cell adhesion", "id": "GO:0007162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007162", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRK5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRK5" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRK5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRK5" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRK5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRK5" } ], "pmid": "" }, { "name": "positive regulation of axonogenesis", "id": "GO:0050772", "url": 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"https://www.uniprot.org/uniprotkb/A0A8C2MRL2/entry#names_and_taxonomy" } ] }, { "name": "protein MB21D2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035300555", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300555" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035300555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300555" } ] }, { "annotation": "Probable nucleotidyltransferase that catalyzes the formation of cyclic dinucleotide second messenger in response to some unknown stimulus.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRL2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRL2#function" }, { "database": "UniProtKB", "id": "ARBA00054069", "url": "https://www.uniprot.org/uniprotkb/ARBA00054069#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRL2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRL2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mb21d2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRL2", "locus": {} } ], "crossref": [ { "id": "100750802", "url": "https://www.ncbi.nlm.nih.gov/gene/100750802", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750802", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750802", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MRL2", "url": "https://www.orthodb.org/?gene=A0A8C2MRL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03281", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03281", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035300555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300555", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MRL2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MRL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKMAAPTASKAASLGCNNKPAFPELDFRSGARVEELNKLIQEFTRHDQREYDDQRALEIHTAKDFIFSMLGMVQKLDQKLPVANEYLLLSGGVREGVVDLDLDELNVYARGTDYDMDFTLLVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISKWKDCCTIADHINGATNYFFSPTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGTIISIILGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPACSYKGKKDNEWRLSFARSEVQLKKCISGSLMQAYQACKAIIIKLLSRPKAISPYHLRSMMLWACDRLPASYLAQEDYAAHFLLGLIDDLQHCLVNKMCPNYFIPQCNMLEHLSEETVMLHARKLSSVRSDPAEHLRTAIEHVKAANRLTLKLQRRGSTTSIPSPQSDGGDPNQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF", "length": 491, "header": "tr|A0A8C2MRL2-1|A0A8C2MRL2_CRIGR Isoform 1 of Nucleotidyltransferase MB21D2 OS=Cricetulus griseus OX=10029 GN=Mb21d2 PE=3 SV=1 CANONICAL=A0A8C2MRL2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MRL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRL2/entry#A0A8C2MRL2-1", "sequence": { "sequence": "MKMAAPTASKAASLGCNNKPAFPELDFRSGARVEELNKLIQEFTRHDQREYDDQRALEIHTAKDFIFSMLGMVQKLDQKLPVANEYLLLSGGVREGVVDLDLDELNVYARGTDYDMDFTLLVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISKWKDCCTIADHINGATNYFFSPTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGTIISIILGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPACSYKGKKDNEWRLSFARSEVQLKKCISGSLMQAYQACKAIIIKLLSRPKAISPYHLRSMMLWACDRLPASYLAQEDYAAHFLLGLIDDLQHCLVNKMCPNYFIPQCNMLEHLSEETVMLHARKLSSVRSDPAEHLRTAIEHVKAANRLTLKLQRRGSTTSIPSPQSDGGDPNQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF", "length": 491, "header": "tr|A0A8C2MRL2-1|A0A8C2MRL2_CRIGR Isoform 1 of Nucleotidyltransferase MB21D2 OS=Cricetulus griseus OX=10029 GN=Mb21d2 PE=3 SV=1 CANONICAL=A0A8C2MRL2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRL2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRL2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRL2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRL2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750802", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750802", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRL2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRL2" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRL2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MRL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRL2" }, { "id": "PF20266", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mab-21-like HhH/H2TH-like", "eco_id": "ECO_0000259", "start_pos": 325, "end_pos": 400, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MRL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRL2" }, { "id": "PF03281", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03281" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mab-21-like nucleotidyltransferase", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 298, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 216, "end_pos": 218 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MRM7-1", "uniprot_ac": "A0A8C2MRM7", "uniprot_id": "A0A8C2MRM7_CRIGR", "mass": { "chemical_mass": 97278.0, "monoisotopic_mass": 97278.0 }, "refseq": { "ac": "XP_035304597", "name": "dipeptidyl aminopeptidase-like protein 6 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304597" }, "gene_names": [ { "name": "Dpp6", "type": "recommended", "evidence": [ { "id": "A0A8C2MRM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRM7" } ] }, { "name": "Dpp6", "type": "synonym", "evidence": [ { "id": "XP_035304597", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304597" } ] } ], "protein_names": [ { "name": "A-type potassium channel modulatory protein DPP6", "type": "recommended", "evidence": [ { "id": "A0A8C2MRM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRM7/entry#names_and_taxonomy" } ] }, { "name": "Dipeptidyl aminopeptidase-like protein 6", "type": "synonym", "evidence": [ { "id": "A0A8C2MRM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRM7/entry#names_and_taxonomy" } ] }, { "name": "Dipeptidyl peptidase 6", "type": "synonym", "evidence": [ { "id": "A0A8C2MRM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRM7/entry#names_and_taxonomy" } ] }, { "name": "Dipeptidyl peptidase VI", "type": "synonym", "evidence": [ { "id": "A0A8C2MRM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRM7/entry#names_and_taxonomy" } ] }, { "name": "dipeptidyl aminopeptidase-like protein 6 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035304597", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304597" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304597", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304597" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRM7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRM7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dpp6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRM7", "locus": {} } ], "crossref": [ { "id": "100774564", "url": "https://www.ncbi.nlm.nih.gov/gene/100774564", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774564", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774564", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MRM7", "url": "https://www.orthodb.org/?gene=A0A8C2MRM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11731", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11731", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11731:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11731:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00930", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00930", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304597", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304597", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MRM7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MRM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLYQRFTGKINTSRSFPAPPEASRLLGGQGPEEDAGPKPLGPQAQAAAPRERGGAGGRPRFQYQARSDCDEEDELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAEDTSLSQKKKVTVEDLFSEDFKIHDPEAKWISDKEFIYRERKGSVILRNVETNNSTVLIEGKKIESLRAIRYEISPDKEYALFSYNVEPVYQHSHTGYYVLSKIPHGDPQSLDPPEVSNAKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVVYNGLSDWLYEEEIWKSHIAHWWSPDGTRLAYATINDSRVPLMELPTYTGSVYPTVKPYHYPKAGSENPSISLHVIGLSGPTHDLEMIPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKHEDESEAWLHRQNEEPVFSKDGRKFFFVRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITSGDWDVTKILSYDEKRNKIYFLSTEDLPRRRQLYSANTVDDFNRQCLSCDLVENCTYFSASFSHNMDYFLLKCEGPGVPTVTVHNTTDKRKIFDLEANEHVQKAINDRQMPKIEYRKIEIEDYSLPMQILKPATFTDTAHYPLLLVVDGTPGSQSVSERFEVTWETVLVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGSLEEKDQMEAVRTMLKEQYIDKTRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKLAHRVSALEDQQFLIIHATADEKIHFQHTAELITQLIKGKANYSLQIYPDESHYFHSVALKQHLYRSIINFFVECFRIQDKLPPATAKEDEEED", "length": 859, "header": "tr|A0A8C2MRM7-1|A0A8C2MRM7_CRIGR Isoform 1 of A-type potassium channel modulatory protein DPP6 OS=Cricetulus griseus OX=10029 GN=Dpp6 PE=3 SV=1 CANONICAL=A0A8C2MRM7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MRM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRM7/entry#A0A8C2MRM7-1", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027251859", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251859" } ] }, { "annotation": "Crystallins are the dominant structural components of the vertebrate eye lens.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F5W8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5W8#function" }, { "database": "UniProtKB", "id": "ARBA00003689", "url": "https://www.uniprot.org/uniprotkb/ARBA00003689#function" }, { "database": "UniProtKB", "id": "A0A8C2MRR9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRR9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRR9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRR9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100759825", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRR9", "locus": {} } ], "crossref": [ { "id": "100759825", "url": "https://www.ncbi.nlm.nih.gov/gene/100759825", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759825", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759825", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MRR9", "url": "https://www.orthodb.org/?gene=A0A8C2MRR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11818:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11818:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027251859", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251859", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MRR9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MRR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F5W8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5W8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F5W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5W8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKITFYEDRSFQGRCYECSSDCPNLQTYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRGDYPDYQQWMGFSDSIRSCRLIPHQTGSHRMRLYEREDHKGLMMELNEDCACIQDRFHLSEVRSLHVLEGCWVLYEMPNYRGRQYLLRPQEYRRYHDWGAVDAKAGSLRRVVDLY", "length": 175, "header": "tr|A0A8C2MRR9-1|A0A8C2MRR9_CRIGR Isoform 1 of Gamma-crystallin C OS=Cricetulus griseus OX=10029 GN=LOC100759825 PE=3 SV=1 CANONICAL=A0A8C2MRR9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MRR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRR9/entry#A0A8C2MRR9-1", "sequence": { "sequence": "MGKITFYEDRSFQGRCYECSSDCPNLQTYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRGDYPDYQQWMGFSDSIRSCRLIPHQTGSHRMRLYEREDHKGLMMELNEDCACIQDRFHLSEVRSLHVLEGCWVLYEMPNYRGRQYLLRPQEYRRYHDWGAVDAKAGSLRRVVDLY", "length": 175, "header": "tr|A0A8C2MRR9-1|A0A8C2MRR9_CRIGR Isoform 1 of Gamma-crystallin C OS=Cricetulus griseus OX=10029 GN=LOC100759825 PE=3 SV=1 CANONICAL=A0A8C2MRR9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F5W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRR9/entry#A0A9J7F5W8-1", "sequence": { "sequence": "MGKITFYEDRSFQGRCYECSSDCPNLQTYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRGDYPDYQQWMGFSDSIRSCRLIPHTGSHRMRLYEREDHKGLMMELNEDCACIQDRFHLSEVRSLHVLEGCWVLYEMPNYRGRQYLLRPQEYRRYHDWGAVDAKAGSLRRVVDLY", "length": 174, "header": "tr|A0A9J7F5W8-1|A0A8C2MRR9_CRIGR Computationally mapped isoform of Gamma-crystallin C OS=Cricetulus griseus OX=10029 GN=LOC100759825 PE=3 SV=1 CANONICAL=A0A8C2MRR9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MRW4-1", "uniprot_ac": "A0A8C2MRW4", "uniprot_id": "A0A8C2MRW4_CRIGR", "mass": { "chemical_mass": 151392.0, "monoisotopic_mass": 151392.0 }, "refseq": { "ac": "XP_027267117", "name": "zinc finger protein 609 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267117" }, "gene_names": [ { "name": "Znf609", "type": "recommended", "evidence": [ { "id": "A0A8C2MRW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW4" } ] }, { "name": "Znf609", "type": "synonym", "evidence": [ { "id": "XP_027267117", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267117" } ] } ], "protein_names": [ { "name": "Zinc finger protein 609 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2MRW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW4/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 609 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027267117", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267117" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267117", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267117" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf609", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW4", "locus": {} } ], "crossref": [ { "id": "100751915", "url": "https://www.ncbi.nlm.nih.gov/gene/100751915", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] 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"length": 1411, "header": "tr|A0A8C2MRW4-1|A0A8C2MRW4_CRIGR Isoform 1 of Zinc finger protein 609 isoform X2 OS=Cricetulus griseus OX=10029 GN=Znf609 PE=4 SV=1 CANONICAL=A0A8C2MRW4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FT15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW4/entry#A0A9J7FT15-1", "sequence": { "sequence": "MSLSSGASGGKGVDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRNKSGKDTNKPTPGTSLFSPSEGAANKKEVQGRSGDGTNAGGLVAAIGPKGSEKAAKASRSIAGSKKEKENSSSKSKKERSEGVGTCSEKDTGVLQPVPLGGRGGQYDGSAGMDTGTVEPLGSIAIEPGAALNPLGTKPEPEEGENECRPLKKVKAEKMESPVSTPSVLPLHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSNNSKTRAGANSKGRRGSQNSSEHRPPPSSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGNKRVRTNSMGSATGPLPGTKVEPNILDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPTLHADLSSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTTTVVQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPGKACRAEEGKSPFRESSGDGIKMEGLLNGSSDSHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLDSTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSVKSKDPEQLVKDGAKKTLFPPQPQNKESPYYQGFESYYSPGYAQSSPGALNSSSQAGMEGQALKTKKDEEPESIEGKVKNDVCEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQSLEQQPRGLDKKTEMGLKEREASLKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVIIPKLDDSSKLPSQAPEGLKGKLGEASHLSKEASEAKTGTECGRQAEVDPILWYRQETEPRMWTYVYPAKYSDIKSEDDRWKEERDRKLKEERSRSKDSVPKEDGKESTSTDCKLPTSEESRLGSKEPRPSVHVPVSSPLTQHQSYIPYMHGYSYSQSYDPNHPSYRGMPAVMMQNYPGSYLPSSYSFSPYGSKVSGGEDADKARASPNVSCKASSESKALDILQQHASHYKSKSPTGFLLQPLLPASKAQLPHSTHPPGGENEHQVPR", "length": 1347, "header": "tr|A0A9J7FT15-1|A0A8C2MRW4_CRIGR Computationally mapped isoform of Zinc finger protein 609 isoform X2 OS=Cricetulus griseus OX=10029 GN=Znf609 PE=4 SV=1 CANONICAL=A0A8C2MRW4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FV05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW4/entry#A0A9J7FV05-1", "sequence": { "sequence": "MSLSSGASGGKGVDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRNKSGKDTNKPTPGTSLFSPSEGAANKKEVQGRSGDGTNAGGLVAAIGPKGSEKAAKASRSIAGSKKEKENSSSKSKKERSEGVGTCSEKDTGVLQPVPLGGRGGQYDGSAGMDTGTVEPLGSIAIEPGAALNPLGTKPEPEEGENECRPLKKVKAEKMESPVSTPSVLPLHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSNNSKTRAGANSKGRRGSQNSSEHRPPPSSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGNKRVRTNSMGSATGPLPGTKVEPNILDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPTLHADLSSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTTTVVQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPGKACRAEEGKSPFRESSGDGIKMEGLLNGSSDSHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLDSTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSVKSKDPEQLVKDGAKKTLFPPQPQNKESPYYQGFESYYSPGYAQSSPGALNSSSQAGMEGQALKTKKDEEPESIEGKVKNDVCEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQSLEQQPRGLDKKTEMGLKEREASLKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVIIPKLDDSSKLPSQAPEGLKGKLGEASHLSKEASEAKTGTECGRQAEVDPILWYRQETEPRMWTYVYPAKYSDIKSEDDRWKEERDRKLKEERSRSKDSVPKEDGKESTSTDCKLPTSEESRLGSKEPRPSVHVPVSSPLTQHQSYIPYMHGYSYSQSYDPNHPSYRGMPAVMMQNYPGSYLPSSYSFSPYGSKVSGGEDADKARASPNVSCKASSESKALDILQQHASHYKSKSPTRLMSTHHHHHHLGYSLLPAQYNLPYAAGLSSTAIVASQQGSTPSLYPPPRR", "length": 1366, "header": "tr|A0A9J7FV05-1|A0A8C2MRW4_CRIGR Computationally mapped isoform of Zinc finger protein 609 isoform X2 OS=Cricetulus griseus OX=10029 GN=Znf609 PE=4 SV=1 CANONICAL=A0A8C2MRW4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 256, "start_aa": "Thr", "end_pos": 256, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr256", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT15" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT15" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751915", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751915", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW4" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": 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"https://www.uniprot.org/uniprotkb/A0A8C2MRW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1287, "end_pos": 1289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 775, "end_pos": 777, "annotation": "n_glycosylation_sequon" }, { "start_pos": 912, "end_pos": 914, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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"sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MRW7-1", "uniprot_ac": "A0A8C2MRW7", "uniprot_id": "A0A8C2MRW7_CRIGR", "mass": { "chemical_mass": 93340.0, "monoisotopic_mass": 93340.0 }, "refseq": { "ac": "XP_003503658", "name": "nuclear pore complex protein Nup93", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503658" }, "gene_names": [ { "name": "Nup93", "type": "recommended", "evidence": [ { "id": "A0A8C2MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7" } ] }, { "name": "Nup93", "type": "synonym", "evidence": [ { "id": "XP_003503658", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503658" } ] } ], "protein_names": [ { "name": "Nuclear pore complex protein Nup93", "type": "recommended", "evidence": [ { "id": "A0A8C2MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7/entry#names_and_taxonomy" } ] }, { "name": "nuclear pore complex protein Nup93", "type": "synonym", "evidence": [ { "id": "XP_003503658", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503658" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613984.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003503658", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503658" } ] }, { "annotation": "Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7#function" }, { "database": "UniProtKB", "id": "ARBA00045728", "url": "https://www.uniprot.org/uniprotkb/ARBA00045728#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nup93", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7", "locus": {} } ], "crossref": [ { "id": "100757790", "url": "https://www.ncbi.nlm.nih.gov/gene/100757790", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757790", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757790", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LLMCGQF", "url": "https://omabrowser.org/oma/group/LLMCGQF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MRW7", "url": "https://www.orthodb.org/?gene=A0A8C2MRW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11225", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11225", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11225:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11225:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04097", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04097", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003503658", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503658", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MRW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETADVKASVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKRTFGMAEEYHRESMLVEWEQVKQRILHTLLASGEDALDFTQESEPSYISDVGPPGRSSLDSIEMAYARQIYIYNEKIVSGHLQPNLVDLCSSVAEMDDKSISDMWAMVKQMTDVVLAPATDALKSRNSVEVRMEFVRQALGYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIKLPAPSPGLQDGEVEGHPVWALIYYCMRCGDLLAASQVVSRAQHQLGEFKTWFQEYMNSKDRRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDITDNQSEVADKTEDYLWLKLNQVCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAIAFLFRMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCMRRLNFVRLLMLYTRKFESTDPREALQYFYFLRDEKDSQGENMFLRCVSELVIESREFDMILGKLENDGSRKPGVIDKFTNDTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNKERLKNMALSIAERYRAQGISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIDRLKLVPLNQESVEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSASRPQRVIEDRDSQLRSQARALITFAGMIPYRTSGDTNARLVQMEVLMN", "length": 819, "header": "tr|A0A8C2MRW7-1|A0A8C2MRW7_CRIGR Isoform 1 of Nuclear pore complex protein Nup93 OS=Cricetulus griseus OX=10029 GN=Nup93 PE=3 SV=1 CANONICAL=A0A8C2MRW7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MRW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7/entry#A0A8C2MRW7-1", "sequence": { "sequence": "MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETADVKASVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKRTFGMAEEYHRESMLVEWEQVKQRILHTLLASGEDALDFTQESEPSYISDVGPPGRSSLDSIEMAYARQIYIYNEKIVSGHLQPNLVDLCSSVAEMDDKSISDMWAMVKQMTDVVLAPATDALKSRNSVEVRMEFVRQALGYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIKLPAPSPGLQDGEVEGHPVWALIYYCMRCGDLLAASQVVSRAQHQLGEFKTWFQEYMNSKDRRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDITDNQSEVADKTEDYLWLKLNQVCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAIAFLFRMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCMRRLNFVRLLMLYTRKFESTDPREALQYFYFLRDEKDSQGENMFLRCVSELVIESREFDMILGKLENDGSRKPGVIDKFTNDTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNKERLKNMALSIAERYRAQGISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIDRLKLVPLNQESVEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSASRPQRVIEDRDSQLRSQARALITFAGMIPYRTSGDTNARLVQMEVLMN", "length": 819, "header": "tr|A0A8C2MRW7-1|A0A8C2MRW7_CRIGR Isoform 1 of Nuclear pore complex protein Nup93 OS=Cricetulus griseus OX=10029 GN=Nup93 PE=3 SV=1 CANONICAL=A0A8C2MRW7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757790", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757790", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480PGC6-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDTDGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETADVKASVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKRTFGMAEEYHRESMLVEWEQVKQRILHTLLASGEDALDFTQESEPSYISDVGPPGRSSLDSIEMAYARQIYIYNEKIVNGHLQPNLVDLCASVAELDDKNISDMWAMVKQMTDVLLAPATDALKSRNSVEVRMEFVRQALGYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIKLPAPLPGLQDGEVEGHPVWALIYYCMRCGDLLAASQVVNRAQHQLGEFKTWFQEYMNSKDRRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDVTDNQSEVADKTEDYLWLKLNQVCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAIAFLFRMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCMRRLNFVRLLMLYTRKFESTDPREALQYFYFLRDEKDSQGENMFLRCVSELVVESREFDMILGKLENDGSRKPGVIDKFTSDTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNKERLKNMALSIAERYRAQGISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIDRLKLVPLNQESVEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSASRPQRVIEDRDSVRSQRWPEPSLRTTFLVCRPLHRLTPLL", "length": 811 }, "evidence": [ { "id": "A0A8C2MRW7", "url": "https://omabrowser.org/oma/group/A0A8C2MRW7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A5PJZ5-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETADVKASVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKRTFGMAEEYHRESMLVEWEQVKQRILHTLLASGEDALDFTQESEPSYISDAGPPGRSSLDSIEMAYARQIYIYNEKIVNGHLQPNLLDLCASVTELDDKNISDMWAMVKQMTDVLLVPATDALKSRNSVEVRMEFVRQALGYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIKLPAPLPGLQDGEVEGHPVWALIYYCMRCGDLLAASQVVNRAQHQLGEFKTWFQEYMNSKDRRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDVTDNQSEVADKTEDYLWLKLNQVCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAIAFLFRMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCMRRLNFVRLLMLYTRKFESTDPREALQYFYFLRDEKDSQGENMFLRCVSELVIESREFDMILGKLENDGSRKPGVIDKFTSDTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPIVPQISAPQSNKERLKNMALSIAERYRAQGISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIDRLKLVPLNQESVEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSATRPQRVIEDRDSQLRSQARALITFAGMIPYRTSGDTNARLVQMEVLMN", "length": 819 }, "evidence": [ { "id": "A0A8C2MRW7", "url": "https://omabrowser.org/oma/group/A0A8C2MRW7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O22224-1", "protein_name": "Nuclear pore complex protein NUP93A", "gene_name": "NUP93A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MANDQEMSGWTDLLHSSSKLLEQAAPSSQFPPLQRNLDQLEALSKKLKAKTLRNEAPSQSIAATRLLAREGINAEQLARDLKSFELKTTFEDVFPAEATSVEEYLQQVHEMAMVSAIQEAQKDNVRSFNDYMMKVLEEDWRKEKRDFLQSLSRISMLPKTNMIDTSREAHAGQLVPVGSSPRVSSTPGKELVALANIPIHEKKAYVYGEVVKKLNTSRERGMPFRPAMCFKDAYDTLGAEVTRGKSVNMQKIWQLVQAITGEDSAVRQGVSKRMALAIGARHHLQHGHEKFIMDTIQTHPTQAALGGSVGNLQRIRAFLRIRLRDYGVLDFDSTDARRQPPVDTTWQQIYFCLRTGYYEEAREIARSTRSSQQFAPLLTEWITTDGMVAAESAAIASEECEKMLRMGDRLGRTAYDKKKLLLYTIISGSRRQIERILRDLSTLFNTIEDFLWFKLSCIRDVTGGSSSVVLNDGLAPYSLDDLQAYLNKFEPSYYTKNGKDPLVYPYVLLLSVQLLPAIMHLSKEAGDGGYNIDAVHIAISLVDHSVLSEGSGTGHKLSVMDSNAEASSMIRQYGSMFLHHGDLQMTVEYYAQAAATVGGGQLAWSGRSNVDQQRQRNLMLKQLLTEILLRERGIYFLLGARGSGEEGQLGRFFPDSRLRQQFLVEAAHQCQEAGLYDKSIELQKRVGAFSAALETINKCLSEAICSLARGRLDGESRTSGLILAGNDILETYKYYPEVSLQERERVMEQETILRELEAILSIHKLGRLGNHLDALREIAKLPFLHLDPRMPDATADVFQSASPYFQTCVPDLLKVALTCLDNVPDTDGSIRAMRSKIAGFLASNTHRNWPRDLYEKVARSF", "length": 861 }, "evidence": [ { "id": "A0A8C2MRW7", "url": "https://omabrowser.org/oma/group/A0A8C2MRW7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P34077-1", "protein_name": "Nucleoporin NIC96", "gene_name": "NIC96", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLETLRGNKLHSGTSKGANKKLNELLESSDNLPSASSELGSIQVSINELRRRVFQLRSKNKASKDYTKAHYLLANSGLSFEDVDAFIKDLQTNQFLEPNPPKIIESEELEFYIRTKKEENILMSIEQLLNGATKDFDNFINHNLNLDWAQHKNEVMKNFGILIQDKKTVDHKKSISSLDPKLPSWGNKGNNILNSNESRLNVNENNILREKFENYARIVFQFNNSRQANGNFDIANEFISILSSANGTRNAQLLESWKILESMKSKDINIVEVGKQYLEQQFLQYTDNLYKKNMNEGLATNVNKIKSFIDTKLKKADKSWKISNLTVINGVPIWALIFYLLRAGLIKEALQVLVENKANIKKVEQSFLTYFKAYASSKDHGLPVEYSTKLHTEYNQHIKSSLDGDPYRLAVYKLIGRCDLSRKNIPAVTLSIEDWLWMHLMLIKEKDAENDPVYERYSLEDFQNIIISYGPSRFSNYYLQTLLLSGLYGLAIDYTYTFSEMDAVHLAIGLASLKLFKIDSSTRLTKKPKRDIRFANILANYTKSFRYSDPRVAVEYLVLITLNEGPTDVELCHEALRELVLETKEFTVLLGKIGRDGARIPGVIEERQPLLHVRDEKEFLHTITEQAARRADEDGRIYDSILLYQLAEEYDIVITLVNSLLSDTLSASDLDQPLVGPDDNSETNPVLLARRMASIYFDNAGISRQIHVKNKEICMLLLNISSIRELYFNKQWQETLSQMELLDLLPFSDELSARKKAQDFSNLDDNIVKNIPNLLIITLSCISNMIHILNESKYQSSTKGQQIDSLKNVARQCMIYAGMIQYRMPRETYSTLINIDVSL", "length": 839 }, "evidence": [ { "id": "A0A8C2MRW7", "url": "https://omabrowser.org/oma/group/A0A8C2MRW7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q66HC5-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "Nup93", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETADVKASVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKRTFGMAEEYHRESMLVEWEQVKQRILHTLLASGEDALDFTQESEPSYVSDVSPPGRSSLDSIEMAYARQIYIYNEKIVSGHLQPNLVDLCASVAELDDKSISDMWAMVKQMTDVVLTPATDALKSRSSVEVRMDFVKQALGYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIKLPAPSPGLQDGEVEGHPVWALIYYCMRCGDLLAASQVVSRAQHQLGEFKTWFQEYMNSKDRRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDITDNQSEVADKTEDYLWLKLNQVCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAIAFLFRMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCMRRLNFVRLLMLYTRKFESTDPREALQYFYFLRDEKDSQGENMFLRCVSELVIESREFDMILGKLENDGSRKPGVIDKFTSDTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNKERLKNMALSIAERYRAQGISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIDRLKLVPLNQESMEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSATRPQRVIEDRDSQLRSQARALITFAGMIPYRTSGDTNARLVQMEVLMN", "length": 819 }, "evidence": [ { "id": "A0A8C2MRW7", "url": "https://omabrowser.org/oma/group/A0A8C2MRW7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7ZU29-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "dye", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDTEGFGELLQQAEQLAAETEAVSELPHVERNLQEIQQAGERLRSRTLTRTSQDTADVKASILLGSRGLDIFHISQRLESLSAATTFEPLEPVKDTDIQGFLKNERDNALLSAIEESRRRTFLLAEEYHRDSMLVQWEQVKQRVLHTLLGAGEDALDFSQEVEPSFVSEVGVPGRSALDSVEVAYSRQIYVFNEKIVNGHLQPNLGDLCASVAESLDDKNVSEMWLMVKQMTDVLLVPAKDTLKSRVSVDMQMAFVRQALQFLENSYKNYTLVTVFGNLHQAQLGGVPGTYQLVCSFLNIKLPTPLPGRQDGEVEGHPVWALIYFCLRCGDLSAAMQVVNKAQHQLGDFKIWFQEYMNSPDRRLSPATENKLRLHYRRVLRNSADPYKRAVYCLIGKCDIGDNHGEVADKTEDYLWLKLNQVCFDEDGSSSPQDRMTLAQLQKQLLEDYGESHFSASHQPFLYFQVLFLTAQFEAAIAFLFRVERLRSHAVHVALVLYELKLLLKSSGQSAQLLSQEAGDPPMVRRLNFIRLLMLYTRKFESTDPREALQYFYFLRNEKDSQGENMFMRCVSELVIESREFDMLLGRLEKDGSRKPGVIDKFAGDTRAIITKVASEAENKGLFEEAVKLYELAKNADKVLELMNKLLSPVIAQVSEPQSNKERLKNMAVAIAERYRANGVAGEKSVDNTFYLLLDLMTFFDEYHAGHIDRAYDVIERLKLVPLSQDSVEERVAAFRNFSDEVRHNLSEVLLATMNILFTQYKRLKGAAAGTPGRPQRTLEDRDMLLRIQARALITFAGMIPYRMAGDTNARLVQMEVLMN", "length": 820 }, "evidence": [ { "id": "A0A8C2MRW7", "url": "https://omabrowser.org/oma/group/A0A8C2MRW7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BJ71-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "Nup93", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETADVKASVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKRTFGMAEEYHRESMLVEWEQVKQRILHTLLASGEDALDFTQESEPSYIGDVNPPGRSSLDSIEMAYARQIYIYNEKIVSGHLQPNLVDLCASVAELDDKSISDMWAMVKQMTDVVLTPATDALKSRSSVEVRMDFVKQALGYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIKLPAPSPGLQDGEVEGHPVWALIYYCMRCGDLLAASQVVSRAQHQLGEFKTWFQEYMNSKDRRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDITDNQSEVADKTEDYLWLKLNQVCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAIAFLFRMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCMRRLNFVRLLMLYTRKFESTDPREALQYFYFLRDEKDSQGENMFLRCVSELVIESREFDMILGKLENDGSRKPGVIDKFTSDTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNKERLKNMALSIAERYRAQGISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIDRLKLVPLNQESVEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSATRPQRVIEDRDSQLRSQARALITFAGMIPYRTSGDTNARLVQMEVLMN", "length": 819 }, "evidence": [ { "id": "A0A8C2MRW7", "url": "https://omabrowser.org/oma/group/A0A8C2MRW7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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}, { "uniprot_canonical_ac": "Q9VFE7-1", "protein_name": "Nuclear pore protein", "gene_name": "Nup93-2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDLNTLLQRAQNLNNDAKAECELPAVERTLQQVLRATTELHSRVTQTGCKEIQAHILLGSKGVDLPKLNQKLEALSARKTFEPLDVKADTDVRTFLKNERENAILSVIEDTKKNISDSANKQRWASMNKVWNEEKTRLLDALIAPSQNFIDLQRLPEPTIVNPLCQPRSCLDPLELVYAQELRHYNELLLKSSHRPNLVQKFAHLSQSFGDCRLTDMWTLLACVTQISEPLRSDPIKSRQQRPEFVTYAKSYLERRYRVFMCSQVGGSYANNSYQLVVAYVNHRFRAQQTIGLVDTVREIPLWPLVYYGLRCGAVKVAVEFLREAGSSHDEFAQLVADRNAGETNSKIENQLRLQYANKIRNSTDAYKKAVYCILLGCDVNEVHGEVAKTIDDFLWMRLAMIQPGDADNYGKLQSMILEQYGEKYFNARQQPYLYFETLALTGQFEAAIEFLARQDENRAHAVHMAIALFELGLLGSARSVSQPLLSIDIKDPQPLRRLNLTRLIRQYVQRFERTDTSEALHYYYTLRCLKDSKGRNMFMACVCDLVVDSGVFDTTIFDLIFGKRQSSDQNDVNSGLFRQFECPEFDTRTMAAQVGDELAALGNFEMSARLYEMAGKYNLAVKHICILMAQVVHLPTLGGSLRERLGQDAQRFNQLLASDSIDVEPKMKSSFVLLQDLLIFFNFYHDGKFNAALDLLRQTQLVPNTLDDVDVVLGNVKQLSGEVIKVLPDVIVAAMEIAQKQYKQLKAGSGSSLEQTQMQQLRQRAKALSNMAATMPYRLPNDTNKRLIELELDMH", "length": 796 }, "evidence": [ { "id": "A0A8C2MRW7", "url": "https://omabrowser.org/oma/group/A0A8C2MRW7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "poly(A)+ mRNA export from nucleus", "id": "GO:0016973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016973", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7" } ], "pmid": "" }, { "name": "nuclear envelope organization", "id": "GO:0006998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006998", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7" } ], "pmid": "" }, { "name": "nuclear pore complex assembly", "id": "GO:0051292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051292", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7" } ], "pmid": "" }, { "name": "positive regulation of SMAD protein signal transduction", "id": "GO:0060391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060391", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7" } ], "pmid": "" }, { "name": "nuclear periphery", "id": "GO:0034399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034399", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 736, "end_pos": 738, "annotation": "n_glycosylation_sequon" }, { "start_pos": 744, "end_pos": 746, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 268, "end_pos": 270 }, { "start_pos": 381, "end_pos": 383 }, { "start_pos": 402, "end_pos": 404 }, { "start_pos": 603, "end_pos": 605 }, { "start_pos": 736, "end_pos": 738 }, { "start_pos": 744, "end_pos": 746 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MRW9-1", "uniprot_ac": "A0A8C2MRW9", "uniprot_id": "A0A8C2MRW9_CRIGR", "mass": { "chemical_mass": 6407.0, "monoisotopic_mass": 6407.0 }, "refseq": { "ac": "XP_016829940", "name": "60S ribosomal protein L39", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829940" }, "gene_names": [ { "name": "Rpl39", "type": "recommended", "evidence": [ { "id": "A0A8C2MRW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW9" } ] }, { "name": "Rpl39", "type": "synonym", "evidence": [ { "id": "XP_016829940", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829940" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein eL39", "type": "recommended", "evidence": [ { "id": "A0A8C2MRW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW9/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L39", "type": "synonym", "evidence": [ { "id": "XP_016829940", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829940" }, { "id": "A0A8C2MRW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613768.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016829940", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829940" } ] }, { "annotation": "RNA-binding component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW9#function" }, { "database": "UniProtKB", "id": "ARBA00046244", "url": "https://www.uniprot.org/uniprotkb/ARBA00046244#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rpl39", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW9", "locus": {} } ], "crossref": [ { "id": "103159665", "url": "https://www.ncbi.nlm.nih.gov/gene/103159665", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103159665", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103159665", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QNWRRMK", "url": "https://omabrowser.org/oma/group/QNWRRMK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MRW9", "url": "https://www.orthodb.org/?gene=A0A8C2MRW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19970", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19970", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19970:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19970:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00832", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016829940", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829940", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MRW9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MRW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51, "header": "tr|A0A8C2MRW9-1|A0A8C2MRW9_CRIGR Isoform 1 of Large ribosomal subunit protein eL39 OS=Cricetulus griseus OX=10029 GN=Rpl39 PE=3 SV=1 CANONICAL=A0A8C2MRW9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MRW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW9/entry#A0A8C2MRW9-1", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51, "header": "tr|A0A8C2MRW9-1|A0A8C2MRW9_CRIGR Isoform 1 of Large ribosomal subunit protein eL39 OS=Cricetulus griseus OX=10029 GN=Rpl39 PE=3 SV=1 CANONICAL=A0A8C2MRW9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MRW9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MRW9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103159665", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103159665", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O16130-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RpL39", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAAHKSFRIKQKLAKKLKQNRSVPQWVRLRTGNTIRYNAKRRHWRRTKLKL", "length": 51 }, "evidence": [ { "id": "A0A8C2MRW9", "url": "https://omabrowser.org/oma/group/A0A8C2MRW9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P62893-1", "protein_name": "Large 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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##RefSeq-Attributes-START## assembly gap :: added 190 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS23", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS23" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"MRFRNRFQRFMNHRAPANGRYKPTCYEHAANCYTHAFLIVPAIVGSALLHRLSDDCWEKITAWIYGMGLCALFIVSTVFHIVSWKKSHLRTVEHCFHMCDRMVIYFFIAASYAPWLNLRELGPLASHMRWFIWLMAAGGTIYVFLYHEKYKVVELFFYLTMGFSPALVVTSMNNTDGLQELACGGLIYCLGVVFFKSDGIIPFAHAIWHLFVATAAAVHYYAIWKYLYRSPTDFIRHL", "length": 238 }, "evidence": [ { "id": "A0A8C2MS23", "url": "https://omabrowser.org/oma/group/A0A8C2MS23/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS23", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS23" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS23", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS23" } ], "pmid": "" } ] }, { 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by automated computational analysis. This record is derived from a genomic sequence (NW_003615879.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003513405", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513405" } ] }, { "annotation": "Orphan receptor. May bind to a neuropeptide and may regulate nociceptor function and/or development, including the sensation or modulation of pain.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS27#function" }, { "database": "UniProtKB", "id": "ARBA00059042", "url": "https://www.uniprot.org/uniprotkb/ARBA00059042#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS27" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mrgprf", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS27", "locus": {} } ], "crossref": [ { "id": "cd15109", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15109", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754930", "url": "https://www.ncbi.nlm.nih.gov/gene/100754930", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754930", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754930", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RILGLCM", "url": "https://omabrowser.org/oma/group/RILGLCM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MS27", "url": "https://www.orthodb.org/?gene=A0A8C2MS27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11334:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11334:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003513405", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513405", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MS27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MS27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS27-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGNCSWEAHSTNQNKMCPGVNEALELYSRGFLTIEQIATPPPPAITNYIFLLLCLCGLVGNGLVLWFFGFSIKRTPFSVYFLHLASADGVYLFSKAVISLLNTGAFLGSFPDYVRRVSRIVGLCTFFAGVSLLPAISTERCVSVIFPIWYWRRRPKRLSAGVCALLWLLSFLVTSIHNYFCMFLGREASGTACRNMDISLGILLFFLFCPLMVLPCLALILHVECRARRRQRSAKLNHVVLAIVSVFLVSSIYLGIDWFLFWVFQIPAPFPEYVTDLCICINSSAKPIVYFLAGRDKSQRLWEPLRVVFQRALRDGAEPGDTATSTPNTVTMEMQCPSGNAS", "length": 343, "header": "tr|A0A8C2MS27-1|A0A8C2MS27_CRIGR Isoform 1 of Mas-related G-protein coupled receptor member F OS=Cricetulus griseus OX=10029 GN=Mrgprf PE=3 SV=1 CANONICAL=A0A8C2MS27-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MS27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS27/entry#A0A8C2MS27-1", "sequence": { "sequence": "MAGNCSWEAHSTNQNKMCPGVNEALELYSRGFLTIEQIATPPPPAITNYIFLLLCLCGLVGNGLVLWFFGFSIKRTPFSVYFLHLASADGVYLFSKAVISLLNTGAFLGSFPDYVRRVSRIVGLCTFFAGVSLLPAISTERCVSVIFPIWYWRRRPKRLSAGVCALLWLLSFLVTSIHNYFCMFLGREASGTACRNMDISLGILLFFLFCPLMVLPCLALILHVECRARRRQRSAKLNHVVLAIVSVFLVSSIYLGIDWFLFWVFQIPAPFPEYVTDLCICINSSAKPIVYFLAGRDKSQRLWEPLRVVFQRALRDGAEPGDTATSTPNTVTMEMQCPSGNAS", "length": 343, "header": "tr|A0A8C2MS27-1|A0A8C2MS27_CRIGR Isoform 1 of Mas-related G-protein coupled receptor member F OS=Cricetulus griseus OX=10029 GN=Mrgprf PE=3 SV=1 CANONICAL=A0A8C2MS27-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS27" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS27" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754930", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754930", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AYM9-1", "protein_name": "Mas-related G-protein coupled receptor member F", "gene_name": "MRGPRF", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGNCSWDAHPTNRNKMCPGVSEAPELYSRGFLTIEQITMLPPPAVMNYIFLLLCLCGLVGNGLVLWFFGFSIKRSPFSIYFLHLASADVGYLFSKAVFSVLNTGGFLSTFADYVRAVCRILGLCMFVTGVSLLPAISLERCLSVLFPHWYWRRRPKRLSAVVCSLLWALSLLVTSIHNYFCVFLGHEASGSGAGCRHMDTFLGILLFLVFCPLMVLPCLALILQVECRARRRQRSAKLNHVVLAMVSVFLVSSIYLGIDWFLFWVFQIPAPFPEYVTDLCICINSSAKPVVYFLAGRDKSQRLWEPLRVVFQRALRDGAELGEAGGGTPNTVTMEMQCPSGNAS", "length": 345 }, "evidence": [ { "id": "A0A8C2MS27", "url": "https://omabrowser.org/oma/group/A0A8C2MS27/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P23749-1", "protein_name": "Mas-related G protein-coupled receptor member F", "gene_name": "Mrgprf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGNCSWEAHSTNQNKMCPGMSEALELYSRGFLTIEQIATLPPPAVTNYIFLLLCLCGLVGNGLVLWFFGFSIKRTPFSIYFLHLASADGIYLFSKAVIALLNMGTFLGSFPDYVRRVSRIVGLCTFFAGVSLLPAISIERCVSVIFPMWYWRRRPKRLSAGVCALLWLLSFLVTSIHNYFCMFLGHEASGTACLNMDISLGILLFFLFCPLMVLPCLALILHVECRARRRQRSAKLNHVVLAIVSVFLVSSIYLGIDWFLFWVFQIPAPFPEYVTDLCICINSSAKPIVYFLAGRDKSQRLWEPLRVVFQRALRDGAEPGDAASSTPNTVTMEMQCPSGNAS", "length": 343 }, "evidence": [ { "id": "A0A8C2MS27", "url": "https://omabrowser.org/oma/group/A0A8C2MS27/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VCJ6-1", "protein_name": "Mas-related G protein-coupled receptor member F", "gene_name": "Mrgprf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGNCSWEAHSTNQNKMCPGMSEARELYSRGFLTIEQIATLPPPAVTNYIFLLLCLCGLVGNGLVLWFFGFSIKRTPFSIYFLHLASADGMYLFSKAVIALLNMGTFLGSFPDYIRRVSRIVGLCTFFTGVSLLPAISIERCVSVIFPTWYWRRRPKRLSAGVCALLWMLSFLVTSIHNYFCMFLGHEAPGTVCRNMDIALGILLFFLFCPLMVLPCLALILHVECRARRRQRSAKLNHVVLAIVSVFLVSSIYLGIDWFLFWVFQIPAPFPEYVTDLCICINSSAKPIVYFLAGRDKSQRLWEPLRVVFQRALRDGAEPGDAASSTPNTVTMEMQCPSGNAS", "length": 343 }, "evidence": [ { "id": "A0A8C2MS27", "url": "https://omabrowser.org/oma/group/A0A8C2MS27/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96AM1-1", "protein_name": "Mas-related G protein-coupled receptor member F", "gene_name": "MRGPRF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGNCSWEAHPGNRNKMCPGLSEAPELYSRGFLTIEQIAMLPPPAVMNYIFLLLCLCGLVGNGLVLWFFGFSIKRNPFSIYFLHLASADVGYLFSKAVFSILNTGGFLGTFADYIRSVCRVLGLCMFLTGVSLLPAVSAERCASVIFPAWYWRRRPKRLSAVVCALLWVLSLLVTCLHNYFCVFLGRGAPGAACRHMDIFLGILLFLLCCPLMVLPCLALILHVECRARRRQRSAKLNHVILAMVSVFLVSSIYLGIDWFLFWVFQIPAPFPEYVTDLCICINSSAKPIVYFLAGRDKSQRLWEPLRVVFQRALRDGAELGEAGGSTPNTVTMEMQCPPGNAS", "length": 343 }, "evidence": [ { "id": "A0A8C2MS27", "url": "https://omabrowser.org/oma/group/A0A8C2MS27/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS27" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS27" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 61, "end_pos": 291, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 283, "end_pos": 285 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MS57-1", "uniprot_ac": "A0A8C2MS57", "uniprot_id": "A0A8C2MS57_CRIGR", "mass": { "chemical_mass": 38241.0, "monoisotopic_mass": 38241.0 }, "refseq": { "ac": "XP_035307283", "name": "paired box protein Pax-4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307283" }, "gene_names": [ { "name": "Pax4", "type": "recommended", "evidence": [ { "id": "A0A8C2MS57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS57" } ] }, { "name": "Pax4", "type": "synonym", "evidence": [ { "id": "XP_035307283", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307283" } ] } ], "protein_names": [ { "name": "Paired box protein Pax-4", "type": "recommended", "evidence": [ { "id": "A0A8C2MS57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS57/entry#names_and_taxonomy" } ] }, { "name": "paired box protein Pax-4", "type": "synonym", "evidence": [ { "id": "XP_035307283", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307283" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307283", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307283" } ] }, { "annotation": "Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that competes with PAX6 in binding to a common element in the glucagon, insulin and somatostatin promoters.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS57", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS57#function" }, { "database": "UniProtKB", "id": "ARBA00057749", "url": "https://www.uniprot.org/uniprotkb/ARBA00057749#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS57", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS57" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pax4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS57", "locus": {} } ], "crossref": [ { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759964", "url": "https://www.ncbi.nlm.nih.gov/gene/100759964", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759964", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759964", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MS57", "url": "https://www.orthodb.org/?gene=A0A8C2MS57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45636", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45636", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45636:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45636:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": 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"MQQDGISSVNQLGGLFVNGRPLPLDTRQQIVQLAMRGMRPCDISRSLKVSNGCVSKILGRYYRTGILEPKGIGGSKPRLATPAVVARIAQLKDEYPAIFAWEIQRQLCAEGLCTQDKAPSVSSINRVLRAQHEDQKLHWTQLRLPALLAPALPSPHSSCEAPRGPHPGTSHRNRTIFSPGQAEALEKEFQRGQYPDSVARGKLAAATSLSEDTVRVWFSNRRAKWRRQEKLKWETQLPGASQDLMVPRVPPGITSAQQSPGSVPSAALPVLEPPSPSFCHLCLGMAPDRCFSDIPSQACLQSSWDCHSLLPVASSSYMEFAWPCLTTPPVYHLIGGPGEAASTHYSHWS", "length": 349, "header": "tr|A0A8C2MS57-1|A0A8C2MS57_CRIGR Isoform 1 of Paired box protein Pax-4 OS=Cricetulus griseus OX=10029 GN=Pax4 PE=3 SV=1 CANONICAL=A0A8C2MS57-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MS57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS57/entry#A0A8C2MS57-1", "sequence": { "sequence": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304772", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304772" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS66", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS66" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100773640", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS66", "locus": {} } ], "crossref": [ { "id": "cd03593", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03593", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773640", "url": "https://www.ncbi.nlm.nih.gov/gene/100773640", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773640", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773640", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RFICERK", "url": "https://omabrowser.org/oma/group/RFICERK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MS66", "url": "https://www.orthodb.org/?gene=A0A8C2MS66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22800", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22800", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22800:SF252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22800:SF252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304772", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304772", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MS66", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MS66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVSRIALWRLMSVIFGIKCLLLMATLGFLMKNSFTIWSIQPIPSPTSIVELQEVSKCCACLEKWIGYQCHCYFISKEGKSWEESRDFCASKNSSLLQLKTKNEMSFMNSSQSHFWIGMRYNEERHAWLWEDGTAPSKDLVPVSSYIKTSGCIAYSPSLFVSTESCENENRFICKQLII", "length": 179, "header": "tr|A0A8C2MS66-1|A0A8C2MS66_CRIGR Isoform 1 of Natural killer cells antigen CD94 OS=Cricetulus griseus OX=10029 GN=LOC100773640 PE=4 SV=1 CANONICAL=A0A8C2MS66-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MS66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS66/entry#A0A8C2MS66-1", "sequence": { "sequence": "MAVSRIALWRLMSVIFGIKCLLLMATLGFLMKNSFTIWSIQPIPSPTSIVELQEVSKCCACLEKWIGYQCHCYFISKEGKSWEESRDFCASKNSSLLQLKTKNEMSFMNSSQSHFWIGMRYNEERHAWLWEDGTAPSKDLVPVSSYIKTSGCIAYSPSLFVSTESCENENRFICKQLII", "length": 179, "header": "tr|A0A8C2MS66-1|A0A8C2MS66_CRIGR Isoform 1 of Natural killer cells antigen CD94 OS=Cricetulus griseus OX=10029 GN=LOC100773640 PE=4 SV=1 CANONICAL=A0A8C2MS66-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027263087", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263087" } ] }, { "annotation": "Probable oxidoreductase that may play a role as regulator of mitochondrial function.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS69", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS69#function" }, { "database": "UniProtKB", "id": "ARBA00037217", "url": "https://www.uniprot.org/uniprotkb/ARBA00037217#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS69", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS69" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pyroxd2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS69", "locus": {} } ], "crossref": [ { "id": "100768114", "url": "https://www.ncbi.nlm.nih.gov/gene/100768114", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768114", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768114", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MS69", "url": "https://www.orthodb.org/?gene=A0A8C2MS69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10668", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10668", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10668:SF103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10668:SF103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01593", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01593", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027263087", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263087", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MS69", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MS69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASLRGLSRALHSSPCPAWKRAQSGTEGRLKPEYDAVVIGAGHNGLVAAAYLQRLGVNTVVFERRHVIGGAAVTEEIIPGFRFSRASYLLSLLRPQIYKDLELKKHGLRLHLRNPYSFTPMLEEGTLSKLPRSLLLGTDMAENQKQISQFSQKDAQAFPRYEEFMSRLVLAIDPLLDSAPVDMAAFQHGSLLQRLRALSTLRPLLKAGRTLGAQLPQYYQVLTGPISKVLDHWFESEPLKATLATDAVIGAMTSPHTPGSGYVLLHHVMGNLEGIQGAWSYVQGGMGALSDAIASSATTHGASIFTEKTVAKVQVNSEGHVQGVILQDGQEVRSRVVLSCASPQVTFLELTPQEWLPETFVKRISQLDTQSPVTKINVAVDRLPNFRAAPNVPRDQPQPHHQCSIHLNCEDTLALHQAFEDAKDGLPSQRPMIELCIPSSLDPTLAPPGCHVVSLFTQYTPYTLAGGKIWDEQEKNNYADKVFDCIEAYAPGFKSSVLARDILTPRDLERIFGLPGGNIFHGAMSLDQLYFARPVPQHSGYRCPIQGLYLCGSGAHPGGGVMGAAGRNAAHEVFRDLKST", "length": 581, "header": "tr|A0A8C2MS69-1|A0A8C2MS69_CRIGR Isoform 1 of Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Pyroxd2 PE=3 SV=1 CANONICAL=A0A8C2MS69-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MS69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS69/entry#A0A8C2MS69-1", "sequence": { "sequence": "MAASLRGLSRALHSSPCPAWKRAQSGTEGRLKPEYDAVVIGAGHNGLVAAAYLQRLGVNTVVFERRHVIGGAAVTEEIIPGFRFSRASYLLSLLRPQIYKDLELKKHGLRLHLRNPYSFTPMLEEGTLSKLPRSLLLGTDMAENQKQISQFSQKDAQAFPRYEEFMSRLVLAIDPLLDSAPVDMAAFQHGSLLQRLRALSTLRPLLKAGRTLGAQLPQYYQVLTGPISKVLDHWFESEPLKATLATDAVIGAMTSPHTPGSGYVLLHHVMGNLEGIQGAWSYVQGGMGALSDAIASSATTHGASIFTEKTVAKVQVNSEGHVQGVILQDGQEVRSRVVLSCASPQVTFLELTPQEWLPETFVKRISQLDTQSPVTKINVAVDRLPNFRAAPNVPRDQPQPHHQCSIHLNCEDTLALHQAFEDAKDGLPSQRPMIELCIPSSLDPTLAPPGCHVVSLFTQYTPYTLAGGKIWDEQEKNNYADKVFDCIEAYAPGFKSSVLARDILTPRDLERIFGLPGGNIFHGAMSLDQLYFARPVPQHSGYRCPIQGLYLCGSGAHPGGGVMGAAGRNAAHEVFRDLKST", "length": 581, "header": "tr|A0A8C2MS69-1|A0A8C2MS69_CRIGR Isoform 1 of Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Pyroxd2 PE=3 SV=1 CANONICAL=A0A8C2MS69-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269155", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269155" } ] }, { "annotation": "Glycoprotein which is a component of the gelatinous extracellular matrix in the cupulae of the vestibular organ.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS91", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS91#function" }, { "database": "UniProtKB", "id": "ARBA00037652", "url": "https://www.uniprot.org/uniprotkb/ARBA00037652#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS91", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS91" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zpld1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS91", "locus": {} } ], "crossref": [ { "id": "100774987", "url": "https://www.ncbi.nlm.nih.gov/gene/100774987", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774987", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774987", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FLMPVCG", "url": "https://omabrowser.org/oma/group/FLMPVCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MS91", "url": "https://www.orthodb.org/?gene=A0A8C2MS91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14002:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14002:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00100", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00100", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269155", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269155", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MS91", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MS91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS91-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERIWLLLLLSARVFPGSAQFNSYNCDANLHSRFPAERDISVYCGVQAITMKINFCTVLFSGYSETDLALNGRHGDSHCRGFINNNTFPAVVIFIINLSTLEGCGNNLVVSTIPGVGASGNATSVQIGNISGYIDTPDPPTVISYLPGLLYKFSCSYPLEYLVNNTQLASSSAAISVRENNGTFVSTLNLLLYNDSTYREPLIIPSIGLPLKTKVFAAVQATNLDGRWNVLMDYCYTTPSGNPNDDTRYDLFLSCDKDPQTTVIENGRSQRGRFSFEVFRFVKHKNQKMSTVFLHCLTKLCRADDCPLLMPICGNRKRRDAGSRTTWVPQSTSGNAVLSAGPIITRSDETPTNNSQLGSLSVPPFQLNATTSSLISGMVILGVMSFSLLLCSLVLLHRKGSSSLVLNGVRNPTFE", "length": 415, "header": "tr|A0A8C2MS91-1|A0A8C2MS91_CRIGR Isoform 1 of Zona pellucida-like domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Zpld1 PE=4 SV=1 CANONICAL=A0A8C2MS91-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MS91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS91/entry#A0A8C2MS91-1", "sequence": { "sequence": "MERIWLLLLLSARVFPGSAQFNSYNCDANLHSRFPAERDISVYCGVQAITMKINFCTVLFSGYSETDLALNGRHGDSHCRGFINNNTFPAVVIFIINLSTLEGCGNNLVVSTIPGVGASGNATSVQIGNISGYIDTPDPPTVISYLPGLLYKFSCSYPLEYLVNNTQLASSSAAISVRENNGTFVSTLNLLLYNDSTYREPLIIPSIGLPLKTKVFAAVQATNLDGRWNVLMDYCYTTPSGNPNDDTRYDLFLSCDKDPQTTVIENGRSQRGRFSFEVFRFVKHKNQKMSTVFLHCLTKLCRADDCPLLMPICGNRKRRDAGSRTTWVPQSTSGNAVLSAGPIITRSDETPTNNSQLGSLSVPPFQLNATTSSLISGMVILGVMSFSLLLCSLVLLHRKGSSSLVLNGVRNPTFE", "length": 415, "header": "tr|A0A8C2MS91-1|A0A8C2MS91_CRIGR Isoform 1 of Zona pellucida-like domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Zpld1 PE=4 SV=1 CANONICAL=A0A8C2MS91-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306175", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306175" } ] }, { "annotation": "6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS97#function" }, { "database": "UniProtKB", "id": "ARBA00058023", "url": "https://www.uniprot.org/uniprotkb/ARBA00058023#function" }, { "database": "UniProtKB", "id": "RU364122", "url": "https://www.uniprot.org/uniprotkb/RU364122#function" }, { "database": "UniProtKB", "id": "A0A8C2MVN5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVN5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { 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"Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MS97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MS97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MVN5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MVN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALPAFAARTLGPPLQPEQGAPARTTCPRRHSRVEAELAASRPGSVAASVHASPPRGVSLGFNSPPLQDKPPKAFSSLAGALRAPLFALLPRGRRRRMHDLRRRWDLGSLCRALLTRGLAAVGHSLKHVLSAIFSKIFGPLASVGNMDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQLLRLQAFSSPVPDPYRSEDESSARFVPRYNFSRSDLLRKVDFDIKGDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCVPAVVDGKRDARLRPSRWRIFQILDSTSKDRWGSSNFNSGANSPSSTKTRSTSKSGKNFHYITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQYNTTRASSVEINEEIQKRIEGLNFLDMELYSFAKDLFLQRYQFMRQKEHQDARRKRQEQRKFLKGRFLQTHFLSQSQSQSQSQGQNQSPGQNLSQSPNPNPNQNLTQNVSQNLTQSSKPNLIRKENRGSQKQGSGQEQSHSSTSNGTNDYIGSVETWR", "length": 656, "header": "tr|A0A8C2MS97-1|A0A8C2MS97_CRIGR Isoform 1 of Heparan-sulfate 6-O-sulfotransferase OS=Cricetulus griseus OX=10029 GN=Hs6st2 PE=3 SV=1 CANONICAL=A0A8C2MS97-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MS97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS97/entry#A0A8C2MS97-1", "sequence": { "sequence": 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"MALPAFAARTLGPPLQPEQGAPARTTCPRRHSRVEAELAASRPGSVAASVHASPPRGVSLGFNSPPLQDKPPKAFSSLAGALRAPLFALLPRGRRRRMHDLRRRWDLGSLCRALLTRGLAAVGHSLKHVLSAIFSKIFGPLASVGNMDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQLLRLQAFSSPVPDPYRSEDESSARFVPRYNFSRSDLLRKVDFDIKGDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCVPAVVDGKRDARLRPSRNFHYITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQYNTTRASSVEINEEIQKRIEGLNFLDMELYSFAKDLFLQRYQFMRQKEHQDARRKRQEQRKFLKGRFLQTHFLSQSQSQSQSQGQNQSPGQNLSQSPNPNPNQNLTQNVSQNLTQSSKPNLIRKENRGSQKQGSGQEQSHSSTSNGTNDYIGSVETWR", "length": 616, "header": "tr|A0A8C2MVN5-1|A0A8C2MVN5_CRIGR Computationally mapped isoform of Heparan-sulfate 6-O-sulfotransferase OS=Cricetulus griseus OX=10029 GN=Hs6st2 PE=3 SV=1 CANONICAL=A0A8C2MS97-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS97" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS97" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763313", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763313", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS97" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS97" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS97" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "heparan sulfate 6-sulfotransferase activity", "id": "GO:0017095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017095", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MS97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MS97" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": 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initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617803.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003515380", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515380" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSH8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSH8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Uchl1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSH8", "locus": {} } ], "crossref": [ { "id": "cd09616", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09616", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766373", "url": "https://www.ncbi.nlm.nih.gov/gene/100766373", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766373", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766373", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CISNGEA", "url": "https://omabrowser.org/oma/group/CISNGEA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MSH8", "url": "https://www.orthodb.org/?gene=A0A8C2MSH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10589", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10589", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10589:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10589:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01088", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01088", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003515380", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515380", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MSH8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MSH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLKPMEINPEMLNKVLAKLGVAGQWRFADVLGLEEEILSTVPTPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKMSPEDRAKCFEKNEAIQAAHDSVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDSLLQDAAKVCREFTEREQGEVRFSAVALCKAP", "length": 223, "header": "tr|A0A8C2MSH8-1|A0A8C2MSH8_CRIGR Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Cricetulus griseus OX=10029 GN=Uchl1 PE=3 SV=1 CANONICAL=A0A8C2MSH8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MSH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSH8/entry#A0A8C2MSH8-1", "sequence": { "sequence": "MQLKPMEINPEMLNKVLAKLGVAGQWRFADVLGLEEEILSTVPTPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKMSPEDRAKCFEKNEAIQAAHDSVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDSLLQDAAKVCREFTEREQGEVRFSAVALCKAP", "length": 223, "header": "tr|A0A8C2MSH8-1|A0A8C2MSH8_CRIGR Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Cricetulus griseus OX=10029 GN=Uchl1 PE=3 SV=1 CANONICAL=A0A8C2MSH8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 44, "start_aa": "Thr", "end_pos": 44, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr44", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003613643.1) annotated using gene prediction method: Gnomon. 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MSK0-1", "uniprot_ac": "A0A8C2MSK0", "uniprot_id": "A0A8C2MSK0_CRIGR", "mass": { "chemical_mass": 65530.0, "monoisotopic_mass": 65530.0 }, "refseq": { "ac": "XP_035301545", "name": "prospero homeobox protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301545" }, "gene_names": [ { "name": "Prox2", "type": "recommended", "evidence": [ { "id": "A0A8C2MSK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSK0" } ] }, { "name": "Prox2", "type": "synonym", "evidence": [ { "id": "XP_035301545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301545" } ] } ], "protein_names": [ { "name": "Prospero homeobox protein 2", "type": "synonym", "evidence": [ { "id": "A0A8C2MSK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSK0/entry#names_and_taxonomy" } ] }, { "name": "prospero homeobox protein 2", "type": "synonym", "evidence": [ { "id": "XP_035301545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301545" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301545" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSK0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Prox2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSK0", "locus": {} } ], "crossref": [ { "id": "100758177", "url": "https://www.ncbi.nlm.nih.gov/gene/100758177", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758177", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758177", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YPIPPRM", "url": "https://omabrowser.org/oma/group/YPIPPRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MSK0", "url": "https://www.orthodb.org/?gene=A0A8C2MSK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12198", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12198", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12198:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12198:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05044", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05044", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035301545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301545", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MSK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLPPVLLSPQSQTGSHLAETCMERERSPPTAELARDSFPSDQVPSSSLTDTDWFGDEHIQAKRARVETIVRGMCLSPSPMVPGSARAKESSCCPEIARERKRKQSLPTHQGPLKSGLGWDCGPKKGETRVKEQLNLLKQQLRHLQEHVLQATEQGPGGAEQRSSPRAKQRNSFLSSPWTVDSKVHQRSNKDTCGAVKPRTAEVHQQAEEPVLRPSGARALVEALRKELNRAVSQAVDSVLQQMLLDPPGHLTRQELSCQRLASEGRNHPSPPQRSAHKEPLALATLPRRVPPQAGVPLGSSSLATPLDPPMCPVSPRAVPKPHQNPLTNCPLTAVSSHIWENQILSQLLGRGPNGHWSGSPQQDSSSQSHTSAESAQQPWVLSQQQLPLSFTSVRLESRPLLPSVKMEQGVLQGVADMIPFSSIHIQEGLSPGHLKKAKLMFFFTRYPSSSLLKAYFPDVQFNRCITSQMIKWFSNFREFYYIQMEKYARQAISDGVTNPKMLTVLRDSEIFRVLNAHYNKGNDFEVPDCFLEIATLTLQEFFRAVSAGKDTDPSWKKPIYKIISKLDSDIPEILKSSNYPQELFRN", "length": 588, "header": "tr|A0A8C2MSK0-1|A0A8C2MSK0_CRIGR Isoform 1 of Prospero homeobox protein 2 OS=Cricetulus griseus OX=10029 GN=Prox2 PE=4 SV=1 CANONICAL=A0A8C2MSK0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MSK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSK0/entry#A0A8C2MSK0-1", "sequence": { "sequence": "MDLPPVLLSPQSQTGSHLAETCMERERSPPTAELARDSFPSDQVPSSSLTDTDWFGDEHIQAKRARVETIVRGMCLSPSPMVPGSARAKESSCCPEIARERKRKQSLPTHQGPLKSGLGWDCGPKKGETRVKEQLNLLKQQLRHLQEHVLQATEQGPGGAEQRSSPRAKQRNSFLSSPWTVDSKVHQRSNKDTCGAVKPRTAEVHQQAEEPVLRPSGARALVEALRKELNRAVSQAVDSVLQQMLLDPPGHLTRQELSCQRLASEGRNHPSPPQRSAHKEPLALATLPRRVPPQAGVPLGSSSLATPLDPPMCPVSPRAVPKPHQNPLTNCPLTAVSSHIWENQILSQLLGRGPNGHWSGSPQQDSSSQSHTSAESAQQPWVLSQQQLPLSFTSVRLESRPLLPSVKMEQGVLQGVADMIPFSSIHIQEGLSPGHLKKAKLMFFFTRYPSSSLLKAYFPDVQFNRCITSQMIKWFSNFREFYYIQMEKYARQAISDGVTNPKMLTVLRDSEIFRVLNAHYNKGNDFEVPDCFLEIATLTLQEFFRAVSAGKDTDPSWKKPIYKIISKLDSDIPEILKSSNYPQELFRN", "length": 588, "header": "tr|A0A8C2MSK0-1|A0A8C2MSK0_CRIGR Isoform 1 of Prospero homeobox protein 2 OS=Cricetulus griseus OX=10029 GN=Prox2 PE=4 SV=1 CANONICAL=A0A8C2MSK0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSK0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSK0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758177", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758177", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XQZ9-1", "protein_name": "Prospero homeobox 2", "gene_name": "PROX2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MIPYQLQGSSLVPRQKEDTRNGRTAPEQDRGCTTTRHSQGLKTEPSFQRDSLLPSPSSSLMSQLLSQAAVSRSLDPCTLFPSSAAELPRGYEFGVPLREAAQALAVTRTCGPAPVPCATDGEQLSDEYLQAKRARVESIIQGMSLPPAHQASYMGKEGGLGQGRERGGEVPHQGKRKPRVSQQQGVRVAGQGAPATGSLHTAECQQLREQLCFLEQQLRCLQKRFSHVCDSGDSAQSQEGAEKVQLLPEKAGDRVDRVGVATTHHPHAATFWESILEADGPSVGEDEEGGGSAGVLPSVARVLSQALKHELAGMTSRVVDSVLKTLWPKAAGHLLQQQLELGPDARGECFPAGKGRKPLAKAPSPSTLGSPRPEAPSLSLGKRSQVRSFSPEGVRNPHQAPSVGHRPGSAAPAVQDSQLLGQLLVYTPHNHWGSPTASERWPLEPPDACWAVTKLRPLAVRPLGPGTVEGNRTTLTPTYEALTPGHLKKAKLMFFFTRYPSSALLRSYFLDVQVDLLWDAGWDRGAWDFSAGLLRAHLSTVPGQFSRCINSQLIKWFSNFREFYYIQVEKFARQALLEGVAEAAALRVSRDSELFRALNMHYNKGNDFQVPSCFLEVASLTLQEFFSAVRAGRDADPSWKKPIYKIISKLDSHIPEVFKAAGCSQELPHN", "length": 670 }, "evidence": [ { "id": "A0A8C2MSK0", "url": "https://omabrowser.org/oma/group/A0A8C2MSK0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZHL7-1", "protein_name": "Prospero homeobox 2", "gene_name": "Prox2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPPAVLLSPQSQTCTHLAETCMGQERSPPTAEVGSDSFFPSGQLPSSSLTDADWFWDEHIQAKRARVETIVRGMCLSPSSLVSGRARESSRCPEKVRERKRKQSLPMHQGPLKSSPAWDRGPKKGGTRVKEQLHLLKQQLRHLQEHVLQATEPRAPAQSPGGTESRSSLGAKARNTFPYSAWAVESKPHQSSSKDIGGAVKPGAAEVLQQSEEPVFCPSGPRALVETLRKELSRAVSQAVDSVLQQVLLDPQSLLPRQDGSCQGLASEGRSQPSPPGRSAYKDPLALATLPRKVQPQAGVPLGNSTLARPLDSPICPVSPRGVPRSYQSPLSNCPLTTVPSHIWENQILSQLLGRGPDGHWSGSPSQDASHQSHTSPESAQQPWGLSQQRLPLSFTPVHLESRPLLPAAVKMEQSALQGVADSLPFSSVHIQEGLSPGHLKKAKLMFFFTRYPSSSLLKAYFPDVQFNRCITSQMIKWFSNFREFYYIQMEKYARQAVSDGVTNAQALAVLRDSELFRVLNTHYNKGNDFEVPECFLQIATLTLQEFFRAVSTGKDSDPSWKKPIYKIISKLDSDIPEILKSSSYSQGLFPS", "length": 593 }, "evidence": [ { "id": "A0A8C2MSK0", "url": "https://omabrowser.org/oma/group/A0A8C2MSK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MW85-1", "protein_name": "Prospero homeobox 2", "gene_name": "PROX2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPNSSLLLGPAQYPTEPCMEGGRSLSPREQSRCSPFAWSQVPSSSFSDPDCFGDEHIQAKRARVETIVQGMFLSPTSLGPGRAPTGDSPSRPEKAQGRKRKQSLPMQQDPLEAGPVGNRGGGRKGGPRVRGQLHMLRQQMRHLQQRILRAVEPRAAAQGPPTADQRNGSRSGPWGADSDHSQGSIGDLSRVEKHRVSEVQYLSEGPRFLPAGARALLESLKKELTGAISQAVDSVLQKVLVDPSGHLTQLGGRFQGPEPDGRSEPLPPEGSARKDPLPLAALPRRAQPPGEAPLGSLSLAKPLDSPRYPVSPRMIPKPYQAPPADCPLAVAPAHIQEEWILGQLLGHGPGGRWRGDLPQDPSAPSQPSSKVALRPWGAAKLRPLALGQQQCPWPFTSTCLERLPLVSPVKMEPGGRQAGMDALPFSAAHIQEGLNPGHLKKAKLMFFFTRYPSSSLLKAYFPDVQFNRCITSQMIKWFSNFREFYYIQMEKFARQAISDGVTNPKMLVILRDSELFRALNMHYNKGNDFEVPDCFLEIASLTLQEFFKAVSSGKDADPSWKKPIYKIISKLDSDIPEIFKSSSYPQELFRN", "length": 592 }, "evidence": [ { "id": "A0A8C2MSK0", "url": "https://omabrowser.org/oma/group/A0A8C2MSK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3B8N5-1", "protein_name": "Prospero homeobox protein 2", "gene_name": "PROX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPNSILLSPQPQICSHLAEACTEGERSSSPPELDRDSPFPWSQVPSSSPTDPEWFGDEHIQAKRARVETIVRGMCLSPNPLVPGNAQAGVSPRCPKKARERKRKQNLPTPQGLLMPAPAWDQGNRKGGPRVREQLHLLKQQLRHLQEHILQAAKPRDTAQGPGGCGTGKGPLSAKQGNGCGPRPWVVDGDHQQGTSKDLSGAEKHQESEKPSFLPSGAPASLEILRKELTRAVSQAVDSVLQKVLLDPPGHLTQLGRSFQGQVAEGRSEPSPPVGGACKDPLALAALPRRVQLQAGVPVGNLSLAKRLDSPRYPIPPRMTPKPCQDPPANFPLTAPSHIQENQILSQLLGHRYNNGHWSSSPPQDSSSQRHPSSEPALRPWRTTKPQPLVLSQQQCPLPFTSAHLESLPLLPSVKMEQRGLHAVMEALPFSLLHIQEGLNPGHLKKAKLMFFFTRYPSSNLLKVYFPDVQFNRCITSQMIKWFSNFREFYYIQMEKSARQAISDGVTNPKMLVVLRNSELFQALNMHYNKGNDFEVPDCFLEIASLTLQEFFRAVSAGRDSDPSWKKPIYKIISKLDSDIPEIFKSSSYPQ", "length": 592 }, "evidence": [ { "id": "A0A8C2MSK0", "url": "https://omabrowser.org/oma/group/A0A8C2MSK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BII1-1", "protein_name": "Prospero homeobox protein 2", "gene_name": "Prox2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPPAAVLLPPQSRTCTHLAEETCMDQERSPATAEAGRDSFPSGQLPSSSLTEADWFWDEHIQAKRARVETIVRGMCLSPSSSVSGRARESLRCPEKGRERKRKQSLPMHQGPLKSSPAWERGPKKGGTRVKEQLHLLKQQLRHLQEHVLQATEPRAPAQSPGGTEPRSSPRARPRNSCSSGAWTVENEPHQSSSKDLCGAVKPGAAEVLQYSEEPMLCPSGPRALVETLRKELSRAVSQAVDSVLQQVLFDPQRHLTQQERSCQGLASEGRNQPSPPGRSAYKDPLALATLPRKIQPQAGVPLGNSTLARPLDSPMCPVSPRGVPRSYQSPLPNCPLTNVPSHTWENQMLRQLLGRGPDGQWSGSPPQDAAFQSHTSPESAQQPWGLSQQQLPLSLTPVHLESRPLPPPVKMEQGVLRGVADSLPFSSIHIQEGLSPGHLKKAKLMFFFTRYPSSSLLKAYFPDVQFNRCITSQMIKWFSNFREFYYIQMEKYARQALSDGITNAQALAVLRDSELFRVLNTHYNKGNDFEVPDCFLEIAALTLKEFFRAVLAGKDSDPSWKKPIYKVISKLDSDVPEMLKSPSFLPGLFPS", "length": 593 }, "evidence": [ { "id": "A0A8C2MSK0", "url": "https://omabrowser.org/oma/group/A0A8C2MSK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "embryonic retina morphogenesis in camera-type eye", "id": "GO:0060059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060059", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSK0" } ], "pmid": "" }, { "name": "tube development", "id": "GO:0035295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035295", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSK0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSK0" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSK0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSK0" } ], "pmid": "" }, { "name": "pancreas development", "id": "GO:0031016", "url": 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This record is derived from a genomic sequence (NW_003613752.1) annotated using gene prediction method: Gnomon. 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK74" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK74" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767080", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767080", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ACR0-1", "protein_name": "Olfactory receptor", "gene_name": "Or7e176", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQQRISLNKCPNNTEAQNLTVVSQFQLMSLSDNPELQPILFVLFLSFYMVTVLGNLLIILAVSSDFHLHTPMYFFLSNLSWSDICLISTTVPKMIWDIRTQSRVISYAGCLTQMSMFIIFGCMDSMLLTVMAYDRFVAICHPLNYNIIMNPNLCALLLLASVLASLVDSQVHNLIVLQFTYFNDMEISNFFCEPSQLLNLKCSEMFTKNIVIRFIGVFFGLFSTSGIIFSYYKIVSSILRIPSTEGKYKAFSTCVSHLSVVCLFYGTAIGVYIGSTASNSSENCKVASLMYTVVTPMLNPFIYSLRNRDIKTALWKLQKKAK", "length": 323 }, "evidence": [ { "id": "A0A8C2MSN4", "url": "https://omabrowser.org/oma/group/A0A8C2MSN4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PVW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or7e176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTQQRISLNKCPNNTEAQNLPVVSQFHLMSLSENVELQPFLLVLFLSFYMVTVLGNLLIILAVCSDFHLHTPMYFFLSNLSWSDICLISTIVPRMIWDIGTQSRVISYVSCLTQMSMFIVFGCMDSMLLTVMAYDRFVAICHPLHYKIIMNPNLCAFLLLASVLASLVDSQVHNLIVLQFTYFNDMEISNFFCDPSQLLNHNCSEMFTKNIVIHFIGVFFGLFSTTGIIFSYYKIISSILRIPTKDGKYKAFSTCGSHLSVVCLFYGTSIGVYIGSTASNSPKNCAIASLMYTVVTPMLNPFIYSLRNRDIKTALWQLQRRAM", "length": 323 }, "evidence": [ { "id": "A0A8C2MSN4", "url": "https://omabrowser.org/oma/group/A0A8C2MSN4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", 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"A0A8C2MSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6/entry#names_and_taxonomy" } ] }, { "name": "cation channel sperm-associated protein 3", "type": "synonym", "evidence": [ { "id": "XP_027263433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263433" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613681.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027263433.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027263433", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263433" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Catsper3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6", "locus": {} } ], "crossref": [ { "id": "100762411", "url": "https://www.ncbi.nlm.nih.gov/gene/100762411", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762411", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762411", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MSQ6", "url": "https://www.orthodb.org/?gene=A0A8C2MSQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47131", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47131", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47131:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47131:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027263433", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263433", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MSQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MSQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQYFHHNPPVRVASSSLFGTASEALYARFKKIKRKDVECQAFFRKVLKNPLFQLLMISTITSNAFFMVLGTDYNIRYKLFRLFEISEILFVSIYACEFFMKVYVEPIKYWRDGYNLLDVVIILIILIRYSLRKIKGRHYRYLHIADGIQSLRILKLISYSRGIRTLITAVGQTVYTVASVLTLLFVLMFIFAILGFCLFGTPEKGDLDNWGNLASAFFTLFSLATVDGWTNLQEQLDKRKFTVSRAFTIIFILLASFIFLNMFVGVMIMHTEDSIKKFQRELMAERHVTLMEEKQMILRNQQEAVNRLMNTQSGGGKNFTELVEEFKKTLRHTDPMVLDDFGSSLPFIDVYFSTLDNQDIVVQKLQELYYEIVNVLCLMLEDLPKKMSSHSSEFMN", "length": 397, "header": "tr|A0A8C2MSQ6-1|A0A8C2MSQ6_CRIGR Isoform 1 of Cation channel sperm-associated protein 3 OS=Cricetulus griseus OX=10029 GN=Catsper3 PE=4 SV=1 CANONICAL=A0A8C2MSQ6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MSQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6/entry#A0A8C2MSQ6-1", "sequence": { "sequence": "MSQYFHHNPPVRVASSSLFGTASEALYARFKKIKRKDVECQAFFRKVLKNPLFQLLMISTITSNAFFMVLGTDYNIRYKLFRLFEISEILFVSIYACEFFMKVYVEPIKYWRDGYNLLDVVIILIILIRYSLRKIKGRHYRYLHIADGIQSLRILKLISYSRGIRTLITAVGQTVYTVASVLTLLFVLMFIFAILGFCLFGTPEKGDLDNWGNLASAFFTLFSLATVDGWTNLQEQLDKRKFTVSRAFTIIFILLASFIFLNMFVGVMIMHTEDSIKKFQRELMAERHVTLMEEKQMILRNQQEAVNRLMNTQSGGGKNFTELVEEFKKTLRHTDPMVLDDFGSSLPFIDVYFSTLDNQDIVVQKLQELYYEIVNVLCLMLEDLPKKMSSHSSEFMN", "length": 397, "header": "tr|A0A8C2MSQ6-1|A0A8C2MSQ6_CRIGR Isoform 1 of Cation channel sperm-associated protein 3 OS=Cricetulus griseus OX=10029 GN=Catsper3 PE=4 SV=1 CANONICAL=A0A8C2MSQ6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762411", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762411", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "CatSper complex", "id": "GO:0036128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036128", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6" } ], "pmid": "" }, { "name": "sperm capacitation", "id": "GO:0048240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048240", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "voltage-gated calcium channel activity", "id": "GO:0005245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ6" }, { "id": "PF00520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ion transport", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 271, "start_aa": "Pro", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 319, "end_pos": 321 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", 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"total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MSR5-1", "uniprot_ac": "A0A8C2MSR5", "uniprot_id": "A0A8C2MSR5_CRIGR", "mass": { "chemical_mass": 28035.0, "monoisotopic_mass": 28035.0 }, "refseq": { "ac": "XP_027281495", "name": "28S ribosomal protein S7, mitochondrial isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281495" }, "gene_names": [ { "name": "Mrps7", "type": "recommended", "evidence": [ { "id": "A0A8C2MSR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR5" } ] }, { "name": "Mrps7", "type": "synonym", "evidence": [ { "id": "XP_027281495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281495" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein uS7m", "type": "recommended", "evidence": [ { "id": "A0A8C2MSR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR5/entry#names_and_taxonomy" } ] }, { "name": "28S ribosomal protein S7, mitochondrial isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027281495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281495" } ] }, { "name": "28S ribosomal protein S7, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A8C2MSR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027281495", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281495" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSR5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mrps7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR5", "locus": {} } ], "crossref": [ { "id": "cd14870", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14870", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756199", "url": "https://www.ncbi.nlm.nih.gov/gene/100756199", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023798", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023798", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756199", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756199", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MSR5", "url": "https://www.orthodb.org/?gene=A0A8C2MSR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11205", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11205", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281495", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281495", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MSR5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MSR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPALQAARRWSGLGPRVRLAVCSLPGITQVRWSRYAPEFRDPLVDKEHHRKPVAELTEEDKYDQELRKTQLFKAAAATQTSSVFADPAISKFTNMMMKGGNKILARSLMAQTLEAVKRKQFEKYRAASAEQQATIERNPYRIFHQALKNCEPVIGLVPILKGGHFYQVPVPLTDRRRRFLAMKWMITECRDNKPRRTLMPEKLSDELLEAFHNRGAVIKRKHNMHKMAEANRALAHYRWW", "length": 242, "header": "tr|A0A8C2MSR5-1|A0A8C2MSR5_CRIGR Isoform 1 of Small ribosomal subunit protein uS7m OS=Cricetulus griseus OX=10029 GN=Mrps7 PE=3 SV=1 CANONICAL=A0A8C2MSR5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MSR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR5/entry#A0A8C2MSR5-1", "sequence": { "sequence": "MAAPALQAARRWSGLGPRVRLAVCSLPGITQVRWSRYAPEFRDPLVDKEHHRKPVAELTEEDKYDQELRKTQLFKAAAATQTSSVFADPAISKFTNMMMKGGNKILARSLMAQTLEAVKRKQFEKYRAASAEQQATIERNPYRIFHQALKNCEPVIGLVPILKGGHFYQVPVPLTDRRRRFLAMKWMITECRDNKPRRTLMPEKLSDELLEAFHNRGAVIKRKHNMHKMAEANRALAHYRWW", "length": 242, "header": "tr|A0A8C2MSR5-1|A0A8C2MSR5_CRIGR Isoform 1 of Small ribosomal subunit protein uS7m OS=Cricetulus griseus OX=10029 GN=Mrps7 PE=3 SV=1 CANONICAL=A0A8C2MSR5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSR5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSR5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756199", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756199", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial small ribosomal subunit", "id": "GO:0005763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005763", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSR5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR5" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSR5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSR5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MSR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR5" }, { "id": "PF00177", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00177" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Small ribosomal subunit protein uS7", "eco_id": "ECO_0000259", "start_pos": 80, "end_pos": 234, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MST6-1", "uniprot_ac": "A0A8C2MST6", "uniprot_id": "A0A8C2MST6_CRIGR", "mass": { "chemical_mass": 67108.0, "monoisotopic_mass": 67108.0 }, "refseq": { "ac": "XP_035294633", "name": "zinc finger protein 271", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294633" }, "gene_names": [ { "name": "LOC118238184", "type": "recommended", "evidence": [ { "id": "A0A8C2MST6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MST6" } ] }, { "name": "LOC118238184", "type": "synonym", "evidence": [ { "id": "XP_035294633", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294633" } ] } ], "protein_names": [ { "name": "Zinc finger protein 271", "type": "recommended", "evidence": [ { "id": "A0A8C2MST6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MST6/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 271", "type": "synonym", "evidence": [ { "id": "XP_035294633", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294633" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035294633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294633" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MST6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MST6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC118238184", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MST6", "locus": {} } ], "crossref": [ { "id": "118238184", "url": "https://www.ncbi.nlm.nih.gov/gene/118238184", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:118238184", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118238184", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YGQSFVW", "url": "https://omabrowser.org/oma/group/YGQSFVW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MST6", "url": "https://www.orthodb.org/?gene=A0A8C2MST6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19818:SF158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19818:SF158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035294633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294633", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MST6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MST6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MST6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MST6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEIQFSCESQEHHLLSDGETKIKIGEPASEEEMTGNIETLAEESGSLTEDVLQNSKSKEFRESGDELNDQNLLERRQYACDECGQSFAWNTGLIRHQRTHWEKPYECDECGKAFRMSSALVLHQRIHTGEKPYPCNWCIKSFSRSSDLIKHQRVHTGEKPYKCDECGKAFSQSSDLIIHQRIHTGEKPYQCSHCRKSFSQRSDMVKHQRIHTGEKPYMCNQCNKHFSQSSDLIKHQRIHTGEKPYKCDVCGKAFSQSSDLILHQRIHTGEKPYPCAQCNKSFSQNSDLIKHRRIHTGEKPYKCSECGKAFNQSSVLILHQRIHTGEKPYPCNQCTKTFSRLSDLINHQRIHTGEKPFPCSQCSKMFSRRSDLVKHYRIHTGEKPYECDECGKTFSQSSNLILHQRIHTGEKPYPCSGCSKSFSRRSDLIKHQRIHTGEKPYTCNLCNKSFSQSSDLTKHQRIHSGEKPYHCDRCDKAFSQSSDLILHHRVHTGEKPYACSQCTRSFSQNSDLIKHQRIHTGEKPYKCNVCGRAFSQCSALTLHQRIHTGEKPYPCAQCGKNFSRRSDLTNHQRIHIGEKLQI", "length": 582, "header": "tr|A0A8C2MST6-1|A0A8C2MST6_CRIGR Isoform 1 of Zinc finger protein 271 OS=Cricetulus griseus OX=10029 GN=LOC118238184 PE=3 SV=1 CANONICAL=A0A8C2MST6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MST6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MST6/entry#A0A8C2MST6-1", "sequence": { "sequence": "MEIQFSCESQEHHLLSDGETKIKIGEPASEEEMTGNIETLAEESGSLTEDVLQNSKSKEFRESGDELNDQNLLERRQYACDECGQSFAWNTGLIRHQRTHWEKPYECDECGKAFRMSSALVLHQRIHTGEKPYPCNWCIKSFSRSSDLIKHQRVHTGEKPYKCDECGKAFSQSSDLIIHQRIHTGEKPYQCSHCRKSFSQRSDMVKHQRIHTGEKPYMCNQCNKHFSQSSDLIKHQRIHTGEKPYKCDVCGKAFSQSSDLILHQRIHTGEKPYPCAQCNKSFSQNSDLIKHRRIHTGEKPYKCSECGKAFNQSSVLILHQRIHTGEKPYPCNQCTKTFSRLSDLINHQRIHTGEKPFPCSQCSKMFSRRSDLVKHYRIHTGEKPYECDECGKTFSQSSNLILHQRIHTGEKPYPCSGCSKSFSRRSDLIKHQRIHTGEKPYTCNLCNKSFSQSSDLTKHQRIHSGEKPYHCDRCDKAFSQSSDLILHHRVHTGEKPYACSQCTRSFSQNSDLIKHQRIHTGEKPYKCNVCGRAFSQCSALTLHQRIHTGEKPYPCAQCGKNFSRRSDLTNHQRIHIGEKLQI", "length": 582, "header": "tr|A0A8C2MST6-1|A0A8C2MST6_CRIGR Isoform 1 of Zinc finger protein 271 OS=Cricetulus griseus OX=10029 GN=LOC118238184 PE=3 SV=1 CANONICAL=A0A8C2MST6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MST6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MST6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MST6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MST6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:118238184", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118238184", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AFH1-1", "protein_name": "Zinc finger protein 271", "gene_name": "ZNF397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVILQLFPEMSNVQLQSMESQFKYESQEHHFLLDGETKDKVGELASEEEITAKIKPLTEESDNSRDDVLQDSECREFCELGENFNGKDQNLFKKRHHNCDKCGQSFAWRTGLIRHQRTHWEKPYECDNCGKAFNVSSALVLHQRIHTGEKPFPCNWCIKSFSRSSDLIKHHRVHTGEKPYKCDECGKAFSQSSDLIIHQRIHTGEKPYQCSHCSKSFSQRSDLVKHQRIHTGEKPYTCNQCNKHFSQSSDVIKHQRIHTGEKPYKCDVCGKAFSQSSDLILHQRIHTGEKPYPCNQCSKSFSQNSDLIKHRRIHTGEKPYKCNECGKAFNQSSVLILHQRIHTGEKPYPCSQCSKTFSRLSDLINHQRIHTGEKPYPCNQCSKMFSRRSDLVKHHRIHTGEKPYECDECGRTFSQSSNLILHQRIHTGEKPYPCNDCTKSFSRRSDLVKHQRIHTGEKPYACSQCNKSFSQSSDLTKHQRVHSGERPYHCNCCEKAFSQSSDLILHQRVHTGEKPYACTQCSRSFSQNSDLIKHQRIHTGEKPYKCNECGKAFSQCSALILHQRIHTGEKPYPCDQCGKSFSRRSDLINHQRIHTSENPYKCDMCGRAFSTFSDLTEHQRIHTEEKTHGCVQCSRSFSQLSDLVNHETVHSGEDTLNAMNMGKPLVCTPTLFSNRDTLPEKKSYECY", "length": 687 }, "evidence": [ { "id": "A0A8C2MST6", "url": "https://omabrowser.org/oma/group/A0A8C2MST6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P15620-1", "protein_name": "Zinc finger protein 271", "gene_name": "Znf271", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIQFSYESQDHHFLSDGETKIKIGEPATEEEMTGKIGTVTEESGSLEEDVPHDSRGKEFREFGEELNDQMLFRRRQYNCDECDQSFAWSTGLIRHQRTHWKPYECEECGKAFRMSSALVLHQRIHTGEKPYPCSWCIKSFSRSSDLIKHQRVHTGEKPYKCDECGKAFSQSSDLMIHQRIHTGEKPYQCSHCSKSFSQHSGMVKHLRIHTGEKPYMCNHCYKHFSQSSDLIKHQRIHTGEKPYKCDVCGKAFSQSSDRILHQRIHTGEKPYPCAQCNKSFSQNSDLIKHRRIHTGEKPYKCSECGKAFNQSSVLILHQRIHTGEKPYPCNQCTKSFSRLSDLINHQRIHTGEKPYPCSQCSKMFSRRSDLVKHYRIHTGEKPYECDKCGKTFSQSSNLILHQRIHTGEKPYPCNSCSKSFSRGSDLIKHQRVHTGEKPYTCNLCSKSFSQSSDLTKHQRVHSGEKPYHCSSCNKAFRQSSDLILHHRVHTGERPYACTQCPRSFSQKSDLIKHQRIHTGEKPYKCMCGKAFSQCSAFTLHQRIHTGEKPYPCAQCGKSFSQRSDLVNHQRVHADQKLQM", "length": 580 }, "evidence": [ { "id": "A0A8C2MST6", "url": "https://omabrowser.org/oma/group/A0A8C2MST6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5FVP4-1", "protein_name": "Zinc finger protein 271", "gene_name": "Zfp35", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEIQFSYESQDHHFLSDGEVQIKIGEPATEEEMTGEIETLTEESGSSQADDAHNSKGSGFFEFGDELNDQMLFGRRQYNCDECGQSFAWNTGLIRHQRTHWKPYECEECGKAFRMSSALVLHQRIHTGEKPYPCSWCIKSFSRSSDLIKHQRVHTGEKPYKCDECGKAFSQSSDLMTHQRIHTGEKPYQCSHCSKSFSQHSGMVKHLRIHTGEKPYMCNHCYKHFSQSSDLIKHERIHTGEKPYKCDVCGKAFSQSSDRILHQRIHTGEKPYPCAQCNKSFSQNSDLIKHRRIHTGEKPYQCSECGKAFNQSSVLILHQRIHTGEKPYPCNQCAKSFSRLSDLINHQRIHTGEKPYPCSQCSKMFSRRSDLVKHYRIHTGEKPYECDKCGKTFSQSSNLILHQRIHTGEKPYPCNSCSKSFSRGSDLIKHQRVHTGEKPYTCNLCNKSFSQSSDLTKHQRVHSGEKPYHCSSCNKAFRQSSDLILHYRVHTGERPYACTQCTRSFSQKSDLIKHQRVHTGEKPYKCVCGKAFSQCSAFTLHQRIHTGERPYPCAQCGKSFTQRSDLVNHQRVHTGQKPQM", "length": 580 }, "evidence": [ { "id": "A0A8C2MST6", "url": "https://omabrowser.org/oma/group/A0A8C2MST6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MST6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MST6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MST6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MST6" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MST6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MST6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MST6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MST6" } ], "pmid": "" }, { "name": "RNA 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027253132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253132" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100762293", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3", "locus": {} } ], "crossref": [ { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00131", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00131", "database": "CDD", 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"MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSSIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPAIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLEPTTTVSASCSQRLEHMKNVDSLPTSQPYCPPTYSTTGYSMDPVTGYQYGQYGQSAFHYLKPDIA", "length": 484, "header": "tr|A0A8C2MSV3-1|A0A8C2MSV3_CRIGR Isoform 1 of Paired box protein Pax-3 isoform X4 OS=Cricetulus griseus OX=10029 GN=LOC100762293 PE=3 SV=1 CANONICAL=A0A8C2MSV3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MSV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3/entry#A0A8C2MSV3-1", "sequence": { "sequence": 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"MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSSIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPAIGNGLSPQLIYQGGKFS", "length": 400, "header": "tr|A0A9J7F9Y0-1|A0A8C2MSV3_CRIGR Computationally mapped isoform of Paired box protein Pax-3 isoform X4 OS=Cricetulus griseus OX=10029 GN=LOC100762293 PE=3 SV=1 CANONICAL=A0A8C2MSV3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FBM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3/entry#A0A9J7FBM5-1", "sequence": { "sequence": "MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSSIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPAIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLEPTTTVSASCSQRLEHMKNVDSLPTSQPYCPPTYSTTGYSMDPVTGYQYGQYGQSAFHYLKPDIA", "length": 483, "header": "tr|A0A9J7FBM5-1|A0A8C2MSV3_CRIGR Computationally mapped isoform of Paired box protein Pax-3 isoform X4 OS=Cricetulus griseus OX=10029 GN=LOC100762293 PE=3 SV=1 CANONICAL=A0A8C2MSV3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F9Y0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9Y0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F9Y0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9Y0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762293", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762293", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "skeletal muscle organ development", "id": "GO:0060538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060538", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3" } ], "pmid": "" }, { "name": "neural tube development", "id": "GO:0021915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021915", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3" } ], "pmid": "" }, { "name": "spinal cord association neuron differentiation", "id": "GO:0021527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021527", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3" } ], "pmid": "" }, { "name": "neuron fate commitment", "id": "GO:0048663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048663", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MSV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 217, "end_pos": 277, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MSV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSV3" }, { "id": "PS51057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Paired", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 161, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MUQ1-1", "uniprot_ac": "A0A8C2MUQ1", "uniprot_id": "A0A8C2MUQ1_CRIGR", "mass": { "chemical_mass": 55192.0, "monoisotopic_mass": 55192.0 }, "refseq": { "ac": "XP_003511870", "name": "tandem C2 domains nuclear protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511870" }, "gene_names": [ { "name": "Tc2n", "type": "recommended", "evidence": [ { "id": "A0A8C2MUQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ1" } ] }, { "name": "Tc2n", "type": "synonym", "evidence": [ { "id": "XP_003511870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511870" } ] } ], "protein_names": [ { "name": "Tandem C2 domains nuclear protein", "type": "recommended", "evidence": [ { "id": "A0A8C2MUQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ1/entry#names_and_taxonomy" } ] }, { "name": "Membrane targeting tandem C2 domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A8C2MUQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ1/entry#names_and_taxonomy" } ] }, { "name": "Tandem C2 protein in nucleus", "type": "synonym", "evidence": [ { "id": "A0A8C2MUQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ1/entry#names_and_taxonomy" } ] }, { "name": "tandem C2 domains nuclear protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003511870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511870" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615240.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003511870", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511870" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tc2n", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ1", "locus": {} } ], "crossref": [ { "id": "cd08684", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08684", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08692", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08692", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100750614", "url": "https://www.ncbi.nlm.nih.gov/gene/100750614", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037788", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037788", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750614", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750614", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QSSARCT", "url": "https://omabrowser.org/oma/group/QSSARCT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MUQ1", "url": "https://www.orthodb.org/?gene=A0A8C2MUQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46887", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46887", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46887:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46887:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003511870", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511870", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MSW2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MSW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEFLKSCCRGCFYGETEKHKFSVEREFKASVSNSQNTICTPPLTSVSVKSQVGCSEDYLLSKLPCDGKEVPFVVPRFKLSYIQPRTQGTPSHLDELEGSARASFGDQKAELCSSFYHGPSYDVYNPCYMYQHFSPDISRRFSPHFETKKMYGSVCDLRTSKLPGSPGLSKSMFDLTTSPQRFIQRHDSLSSVPSSSSSRKNSQGSNRSLDTITLSGDERDLGRLNVKLFYNSSAEQIWITVLQCRDVIWPSNYGDTPTISIKGILTLSKPVHFKSSAKEGSNAIEFMETFVFAIKLQNLQTVRLVFKIQTQTPRKKTIGECSLSLRTLSTQEMDYSLEIIPPSKISVCHSELELGTCFQAVNSRIQLQILEAQYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASSGRVKWGETMIFPLTQTEKEIVFLVKLYSRSSVRRKHFVGQLWISEDSNNTEAVNQWKETITNPEKVVIKWHKLNPS", "length": 489, "header": "tr|A0A8C2MUQ1-1|A0A8C2MUQ1_CRIGR Isoform 1 of Tandem C2 domains nuclear protein OS=Cricetulus griseus OX=10029 GN=Tc2n PE=4 SV=1 CANONICAL=A0A8C2MUQ1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MSW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ1/entry#A0A8C2MSW2-1", "sequence": { "sequence": "MAAEFLKSCCRGCFYGETEKHKFSVEREFKASVSNSQNTICTPPLTSVSVKSQVGCSEDYLLSKLPCDGKEVPFVVPRFKLSYIQPRTQGTPSHLDELEGSARASFGDQKAELCSSFYHGPSYDVYNPCYMYQHFSPDISRRFSPHFETKKMYGSVCDLRTSKLPGSPGLSKSMFDLTTSPQRFIQRHDSLSSVPSSSSSRKNSQGSNRSLDTITLSGDERDLGRLNVKLFYNSSAEQIWITVLQCRDVIWPSNYGDTPTISIKGILTLSKPVHFKSSAKEGSNVCHSELELGTCFQAVNSRIQLQILEAQYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASSGRVKWGETMIFPLTQTEKEIVFLVKLYSRSSVRRKHFVGQLWISEDSNNTEAVNQWKETITNPEKVVIKWHKLNPS", "length": 425, "header": "tr|A0A8C2MSW2-1|A0A8C2MUQ1_CRIGR Computationally mapped isoform of Tandem C2 domains nuclear protein OS=Cricetulus griseus OX=10029 GN=Tc2n PE=4 SV=1 CANONICAL=A0A8C2MUQ1-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MUQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ1/entry#A0A8C2MUQ1-1", "sequence": { "sequence": "MAAEFLKSCCRGCFYGETEKHKFSVEREFKASVSNSQNTICTPPLTSVSVKSQVGCSEDYLLSKLPCDGKEVPFVVPRFKLSYIQPRTQGTPSHLDELEGSARASFGDQKAELCSSFYHGPSYDVYNPCYMYQHFSPDISRRFSPHFETKKMYGSVCDLRTSKLPGSPGLSKSMFDLTTSPQRFIQRHDSLSSVPSSSSSRKNSQGSNRSLDTITLSGDERDLGRLNVKLFYNSSAEQIWITVLQCRDVIWPSNYGDTPTISIKGILTLSKPVHFKSSAKEGSNAIEFMETFVFAIKLQNLQTVRLVFKIQTQTPRKKTIGECSLSLRTLSTQEMDYSLEIIPPSKISVCHSELELGTCFQAVNSRIQLQILEAQYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASSGRVKWGETMIFPLTQTEKEIVFLVKLYSRSSVRRKHFVGQLWISEDSNNTEAVNQWKETITNPEKVVIKWHKLNPS", "length": 489, "header": "tr|A0A8C2MUQ1-1|A0A8C2MUQ1_CRIGR Isoform 1 of Tandem C2 domains nuclear protein OS=Cricetulus griseus OX=10029 GN=Tc2n PE=4 SV=1 CANONICAL=A0A8C2MUQ1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSW2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSW2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSW2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSW2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750614", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750614", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YYB4-1", "protein_name": "Tandem C2 domains, nuclear", "gene_name": "TC2N", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MANEYIKNCCKWCFYVEKEKSNSVSMAQESEAVPASKPTIVEQPPLSSVSVKRQVGCSEDYLLSKLPLDGQEVPFVVPPFKLAYVQPKSHPSTSHAGGIQESARASFGDRKAELCGVYQWPRYDVYNPFYLEHHVSPDQIRRFQAKSDNRKLYGSVSDLRTSALPGSLDLSHSMFDLRSPPHRFMKRYDSVSSVPSSTSSRKDSHGSNRSLDTITLSGDERDFGRLNVKLCYVPSVEQIWITVLHCKGLSWPSGCGENPRIYVKGILTLPKPVQFKSSAKEGSNDIEFMETFVFAIKLQSVQAVRLVFKIQMQTPRKRTIGECSLSLRELSSEESNHWLDISPPSKAPVCRTELQIGTCFQAINRRIQLQILEAQNLPISSTPLSLSFFVKVGMFSTEGLIYKKKTRLVKSTNGQVKWREMMIFPVSQAEQGIGFLIKLYSRSSVRRKHFLGQVWISSDSNNSEAVEQWEDTIANPEKVVIKWYSLGPS", "length": 489 }, "evidence": [ { "id": "A0A8C2MUQ1", "url": "https://omabrowser.org/oma/group/A0A8C2MUQ1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SD88-1", "protein_name": "Tandem C2 domains nuclear protein", "gene_name": "TC2N", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATEFIKSCCRGCFYGDPEKHNLSVERDFKAAVSNSHDTTICIPPLTSVSVKPQVGCTEDYLLSKLPSDGKEVPFVVPKFKLAYIQPRTQGTPSHLEELEGSARASFVDRKVELSSSSQHGPSYDVYNPFYMYQHVSPDLSRRFPPHSEATRLYGSVCDLRTNRLPSSPGLSKSMFDLTSSSQRFIQRHDSLSSVPSSSSSRKNSQGSNRSLDTITLSGDERDLGRLNVKVFYNSSVEQIWITILQCRDLSWPSSYGDTPTLSIKGILTLPKPVHFKSSVKEGSSNIEFMETFVFAIKLQNLQTVRLVFKIQTQTPRKKTIGECSLSLRTLSTQEMDYSLDISPPSKISVCHAELELGTCFQAVNSRIQLQILEAQYLPSSSTPLTLSFFVKVAMFSSGELIYKKKTRLLKASSGRVKWGETMIFPLIQNEKEIIFLVKLYSRSSVGRRHFVGQIWISEDSNNIEAVNQWKETITNPEKVVIKWHKLNPS", "length": 490 }, "evidence": [ { "id": "A0A8C2MUQ1", "url": "https://omabrowser.org/oma/group/A0A8C2MUQ1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8N9U0-1", "protein_name": "Tandem C2 domains nuclear protein", "gene_name": "TC2N", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATEFIKSCCGGCFYGETEKHNFSVERDFKAAVPNSQNATISVPPLTSVSVKPQLGCTEDYLLSKLPSDGKEVPFVVPKFKLSYIQPRTQETPSHLEELEGSARASFGDRKVELSSSSQHGPSYDVYNPFYMYQHISPDLSRRFPPRSEVKRLYGSVCDLRTNKLPGSPGLSKSMFDLTNSSQRFIQRHDSLSSVPSSSSSRKNSQGSNRSLDTITLSGDERDFGRLNVKLFYNSSVEQIWITVLQCRDLSWPSSYGDTPTVSIKGILTLPKPVHFKSSAKEGSNAIEFMETFVFAIKLQNLQTVRLVFKIQTQTPRKKTIGECSMSLRTLSTQEMDYSLDITPPSKISVCHAELELGTCFQAVNSRIQLQILEARYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASNGRVKWGETMIFPLIQSEKEIVFLIKLYSRSSVRRKHFVGQIWISEDSNNIEAVNQWKETVINPEKVVIRWHKLNPS", "length": 490 }, "evidence": [ { "id": "A0A8C2MUQ1", "url": "https://omabrowser.org/oma/group/A0A8C2MUQ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91XT6-1", "protein_name": "Tandem C2 domains nuclear protein", "gene_name": "Tc2n", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAEFIKSCCRGCLYGETEKQKFSVDRDFKASASSSQNTIGIPPLTSVLVKPQVGCNEDYLLSKLPCDGKEVQFVVPRFKLSYIQPRTQGIPSHLDELEGSARASFGDQKTELCSSFYHGPSYDVYNPCYMYQHFSPDLSRRFLPHCETKQLYGSVCDLRTSKLPGSSGLSKSMLDLTTSSQRFIQRHDSFSSVPSSSSSRKNSQGSNRSLDTITLSGDERDLGRLNVKLFYNSSAEQIWITVLQCRDISWPSSYGDTPTISIKGILTLSKPVHFKSSAKEGSNAIEFMETFVFAIKLQNLQAVRLAFKIQTQTPKKKTIGECSLSLRTLSTQEMEYSLEIIAPSKISVCQAELELGTCFQAVNSRIQLQILEAQYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASSGRVKWGETMIFPLIQTEKEIVFLIKLYSRSSVRRKHFVGQLWISEDSNNIEAVNQWKETITNPEKVVIKWHKLNPS", "length": 489 }, "evidence": [ { "id": "A0A8C2MUQ1", "url": "https://omabrowser.org/oma/group/A0A8C2MUQ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MUQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ1" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 222, "end_pos": 341, "start_aa": "Asp", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 208, "end_pos": 210 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 461, "end_pos": 463 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MSW7-1", "uniprot_ac": "A0A8C2MSW7", "uniprot_id": "A0A8C2MSW7_CRIGR", "mass": { "chemical_mass": 29752.0, "monoisotopic_mass": 29752.0 }, "refseq": { "ac": "XP_035299443", "name": "uroplakin-1b", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299443" }, "gene_names": [ { "name": "Upk1b", "type": "recommended", "evidence": [ { "id": "A0A8C2MSW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSW7" } ] }, { "name": "Upk1b", "type": "synonym", "evidence": [ { "id": "XP_035299443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299443" } ] } ], "protein_names": [ { "name": "Uroplakin-1b", "type": "recommended", "evidence": [ { "id": "A0A8C2MSW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSW7/entry#names_and_taxonomy" } ] }, { "name": "Uroplakin Ib", "type": "synonym", "evidence": [ { "id": "A0A8C2MSW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSW7/entry#names_and_taxonomy" } ] }, { "name": "uroplakin-1b", "type": "synonym", "evidence": [ { "id": "XP_035299443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299443" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035299443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299443" } ] }, { "annotation": "Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSW7#function" }, { "database": "UniProtKB", "id": "ARBA00049584", "url": "https://www.uniprot.org/uniprotkb/ARBA00049584#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSW7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Upk1b", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSW7", "locus": {} } ], "crossref": [ { "id": "cd03156", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03156", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759168", "url": "https://www.ncbi.nlm.nih.gov/gene/100759168", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759168", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759168", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EKCCGVN", "url": "https://omabrowser.org/oma/group/EKCCGVN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MSW7", "url": "https://www.orthodb.org/?gene=A0A8C2MSW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47110", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47110", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47110:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47110:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035299443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299443", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MSW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MSW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSW7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKDDSTVRCFQGLLIFGHVIVGMCGIALTAECIFFVSDQHSLYPLLEATNNDDIYGAAWIGMFVGICLFCLSVLAIVGILKSNRKILLAYFIMMFIVYGFEVASCITAATQRDFFTANLFLKQMLVRYQNNSPPTNDDEWKNNGVTKTWDRLMLQEHCCGVNGPSDWQKYTSAFRVENNDADYPWPRQCCVMNKLKEPLNLDACKLGVPGYYHNQGCYELISAPMDRHAWGVAWFGFAILCWTFWVLLGTMFYWSRIEY", "length": 260, "header": "tr|A0A8C2MSW7-1|A0A8C2MSW7_CRIGR Isoform 1 of Uroplakin-1b OS=Cricetulus griseus OX=10029 GN=Upk1b PE=3 SV=1 CANONICAL=A0A8C2MSW7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MSW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSW7/entry#A0A8C2MSW7-1", "sequence": { "sequence": "MAKDDSTVRCFQGLLIFGHVIVGMCGIALTAECIFFVSDQHSLYPLLEATNNDDIYGAAWIGMFVGICLFCLSVLAIVGILKSNRKILLAYFIMMFIVYGFEVASCITAATQRDFFTANLFLKQMLVRYQNNSPPTNDDEWKNNGVTKTWDRLMLQEHCCGVNGPSDWQKYTSAFRVENNDADYPWPRQCCVMNKLKEPLNLDACKLGVPGYYHNQGCYELISAPMDRHAWGVAWFGFAILCWTFWVLLGTMFYWSRIEY", "length": 260, "header": "tr|A0A8C2MSW7-1|A0A8C2MSW7_CRIGR Isoform 1 of Uroplakin-1b OS=Cricetulus griseus OX=10029 GN=Upk1b PE=3 SV=1 CANONICAL=A0A8C2MSW7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSW7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSW7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759168", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759168", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F6Q8K1-1", "protein_name": "Uroplakin-1b", "gene_name": "UPK1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKDDSTVRCFQSLLVFGNVIIGMCGIALTAECIFFVSDQYSLYPLLEATDNDDIYGAAWIGIFVGICLFCLSVLGIVGIMKSNRKILLVYFILMFIVYGFEVASCITAATQRDFFTPNLFLKQMLERYQNNSPPSNDDKWKNNGVTKTWDRLMLQDYCCGVNGPSDWQKYTSAFRTENNDADPWPRQCCVMNKLKEPLNLEACKLGVPGYYHNQGCYELISGPMNRHAWGVAWFGFAILCWTFWVLLGTMFYWSRIEY", "length": 259 }, "evidence": [ { "id": "A0A8C2MSW7", "url": "https://omabrowser.org/oma/group/A0A8C2MSW7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75841-1", "protein_name": "Uroplakin-1b", "gene_name": "UPK1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDNSTVRCFQGLLIFGNVIIGCCGIALTAECIFFVSDQHSLYPLLEATDNDDIYGAAWIGIFVGICLFCLSVLGIVGIMKSSRKILLAYFILMFIVYAFEVASCITAATQQDFFTPNLFLKQMLERYQNNSPPNNDDQWKNNGVTKTWDRLMLQDNCCGVNGPSDWQKYTSAFRTENNDADYPWPRQCCVMNNLKEPLNLEACKLGVPGFYHNQGCYELISGPMNRHAWGVAWFGFAILCWTFWVLLGTMFYWSRIEY", "length": 260 }, "evidence": [ { "id": "A0A8C2MSW7", "url": "https://omabrowser.org/oma/group/A0A8C2MSW7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q566D0-1", "protein_name": "Uroplakin-1b", "gene_name": "Upk1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKDDSTVRCFQGLLIFGHVIVGMCGIALTAECIFFVSDQHSLYPLLEATNNDDIFGAAWIGMFVGICLFCLSVLAIVGIMKSNRKILLAYFIMMFIVYGFEVASCITAATQRDFFTTNLFLKQMLMRYQNNSPPTNDDKWKNSYVTKTWDRLMLQDHCCGVNGPSDWQKYTSAFRVENSDADYPWPRQCCVMDKLQEPLNLDACKLGVPGYYHSQGCYELISGPMDRHAWGVAWFGFAILCWTFWVLLGTMFYWSRIEY", "length": 260 }, "evidence": [ { "id": "A0A8C2MSW7", "url": "https://omabrowser.org/oma/group/A0A8C2MSW7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Z2C6-1", "protein_name": "Uroplakin-1b", "gene_name": "Upk1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKDDSTVRCFQGLLIFGHVIVGMCGIALTAECIFFVSDQHSLYPLLEATNNDDIFGAAWIGMFVGICLFCLSVLAIVGIMKSNRKILLAYFIMMFIVYGFEVASCITAATQRDFFTTNLFLKQMLMRYQNNSPPTNDDEWKNNGVTKTWDRLMLQDHCCGVNGPSDWQKYTSAFRVENNDADYPWPRQCCVMDKLKEPLNLDACKLGVPGYYHSQGCYELISGPMDRHAWGVAWFGFAILCWTFWVLLGTMFYWSRIEY", "length": 260 }, "evidence": [ { "id": "A0A8C2MSW7", "url": "https://omabrowser.org/oma/group/A0A8C2MSW7/", "database": "OMA" } ], 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MT62", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MT62" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766458", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766458", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QXI3-1", "protein_name": "Caspase-6", "gene_name": "CASP6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSALDLRGAGEEQNMTETDAFPKREVFDPAEKYKMDHKRRGVALIFNHERFFWHLTLPERRGTSADRDNLKRRFSDLGFEVKCFNDLRAEELLLKIHEASTASHVDADCFLCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGNQHDVPVLPLDVVDHQTDKLDANLTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKFGSSLEFTELLTLVNRKVSQRRVDFCKDPDAIGKKFSFGLCKNSEAILSTVLVSAFP", "length": 292 }, "evidence": [ { "id": "A0A8C2MT62", "url": "https://omabrowser.org/oma/group/A0A8C2MT62/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O08738-1", "protein_name": "Caspase-6", "gene_name": "Casp6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTETDGFYKSREVFDPAEQYKMDHKRRGVALIFNHERFFWHLTLPERRGTNADRDNLTRRFSDLGFEVKCFNDLRAEELLLKIHEVSTSSHIDADCFICVFLSHGEGNHVYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGSQHDVPVVPLDMVDHQTDKLDNVTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLARYGSSLEFTELLTLVNRKVSQRRVDFCKDPDAIGKKQVPCFASMLTKKLHFCPKPSK", "length": 276 }, "evidence": [ { "id": "A0A8C2MT62", "url": "https://omabrowser.org/oma/group/A0A8C2MT62/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O35397-1", "protein_name": "Caspase-6", "gene_name": "Casp6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTETDGFYRSREVLDPAEQYKMDHKRRGTALIFNHERFFWHLALPERRGTNADRDNPTRRFSELGFEVKCFNDLRAEELLLKIHEVSTSSHVDADCFLCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGSQHDVPLVPLDVVDHQTDKLDDNVTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLSEMLARHGSSLEFTELLTLVNRKVSQRRVDFCKDPGAIGKKQVPCFASMLTKKLHFCPKPSK", "length": 277 }, "evidence": [ { "id": "A0A8C2MT62", "url": "https://omabrowser.org/oma/group/A0A8C2MT62/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P55212-1", "protein_name": "Caspase-6", "gene_name": "CASP6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSASGLRRGHPAGGEENMTETDAFYKREMFDPAEKYKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHDVPVIPLDVVDNQTEKLDTNITEVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQVPCFASMLTKKLHFFPKSN", "length": 293 }, "evidence": [ { "id": "A0A8C2MT62", "url": "https://omabrowser.org/oma/group/A0A8C2MT62/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MT62", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MT62" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MT62", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MT62" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MT62", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MT62" } ], "pmid": "" }, { "name": "apoptotic 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"n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MT62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MT62" }, { "id": "PS50207", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50207" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Caspase family p10", "eco_id": "ECO_0000259", "start_pos": 178, "end_pos": 272, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MT62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MT62" }, { "id": "PS50208", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50208" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Caspase family p20", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 150, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.22.59", "ec_name": "Strict requirement for Asp at position P1 and has a preferred cleavage sequence of Val-Glu-His-Asp-|-.", "evidence": [ { "id": "3.4.22.59", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.22.59" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 170, "end_pos": 172 }, { "start_pos": 206, "end_pos": 208 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"monoisotopic_mass": 14252.0 }, "refseq": { "ac": "XP_003510394", "name": "prefoldin subunit 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510394" }, "gene_names": [ { "name": "Pfdn1", "type": "recommended", "evidence": [ { "id": "A0A8C2MTB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB7" } ] }, { "name": "Pfdn1", "type": "synonym", "evidence": [ { "id": "XP_003510394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510394" } ] } ], "protein_names": [ { "name": "Prefoldin subunit 1", "type": "recommended", "evidence": [ { "id": "A0A8C2MTB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB7/entry#names_and_taxonomy" } ] }, { "name": "prefoldin subunit 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003510394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510394" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614866.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510394", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510394" } ] }, { "annotation": "Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTB7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB7#function" }, { "database": "UniProtKB", "id": "ARBA00024667", "url": "https://www.uniprot.org/uniprotkb/ARBA00024667#function" }, { "database": "UniProtKB", "id": "A0A9J7JGC7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGC7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTB7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pfdn1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB7", "locus": {} } ], "crossref": [ { "id": "cd23164", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23164", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752168", "url": "https://www.ncbi.nlm.nih.gov/gene/100752168", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752168", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752168", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "REMIQQK", "url": "https://omabrowser.org/oma/group/REMIQQK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MTB7", "url": "https://www.orthodb.org/?gene=A0A8C2MTB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JGC7", "url": "https://www.orthodb.org/?gene=A0A9J7JGC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20903", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20903", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20903:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20903:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510394", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510394", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MTB7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MTB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGC7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPVDLELKKAFTELQAKVIDTQQKVKLADIQIEQLNRTKKHAHLTDTEIMTLVDETNMYEGVGRMFILQSKEVIHNQLLEKQKVAEEKIKELEQKKSYLERSVKEAEDNIREMLMARRAQ", "length": 122, "header": "tr|A0A8C2MTB7-1|A0A8C2MTB7_CRIGR Isoform 1 of Prefoldin subunit 1 OS=Cricetulus griseus OX=10029 GN=Pfdn1 PE=3 SV=1 CANONICAL=A0A8C2MTB7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MTB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB7/entry#A0A8C2MTB7-1", "sequence": { "sequence": "MAAPVDLELKKAFTELQAKVIDTQQKVKLADIQIEQLNRTKKHAHLTDTEIMTLVDETNMYEGVGRMFILQSKEVIHNQLLEKQKVAEEKIKELEQKKSYLERSVKEAEDNIREMLMARRAQ", "length": 122, "header": "tr|A0A8C2MTB7-1|A0A8C2MTB7_CRIGR Isoform 1 of Prefoldin subunit 1 OS=Cricetulus griseus OX=10029 GN=Pfdn1 PE=3 SV=1 CANONICAL=A0A8C2MTB7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JGC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB7/entry#A0A9J7JGC7-1", "sequence": { "sequence": "MAAPVDLELKKAFTELQAKVIDTQQKVKLADIQIEQLNRTKKHAHLTDTEIMTLVDETNMYEGVGRMFILQSKEVIHNQLLEKQKVAEEKIKELEDFSMKP", "length": 101, "header": "tr|A0A9J7JGC7-1|A0A9J7JGC7_CRIGR Computationally mapped isoform of Prefoldin subunit 1 OS=Cricetulus griseus OX=10029 GN=Pfdn1 PE=3 SV=1 CANONICAL=A0A8C2MTB7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTB7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTB7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752168", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752168", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BED1-1", "protein_name": "Prefoldin subunit 1", "gene_name": "PFDN1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAPVDLELKKAFTELQAKVIDTQQKVKLADIQIEQLNRTKKHAHLTDTEIMTLVDETNMYEGVGRMFILQSKEAIHNQLLEKQKIAEEKIKELEQKKSYLERSVKEAEDNIREMLMARRAQ", "length": 122 }, "evidence": [ { "id": "A0A8C2MTB7", "url": "https://omabrowser.org/oma/group/A0A8C2MTB7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZX38-1", "protein_name": "Prefoldin subunit 1", "gene_name": "Pfdn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASVDLELKKAFTELQAKVIDTQQKVKLADIQIEQLNRTKKHAHLTDTEIMTLVDETNMYEGVGRMFILQSKEVIHNQLLEKQKIAEEKIKELEQKKSYLERSVKEAEDNIREMLMARRAQ", "length": 122 }, "evidence": [ { "id": "A0A8C2MTB7", "url": "https://omabrowser.org/oma/group/A0A8C2MTB7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NDS5-1", "protein_name": "Prefoldin subunit 1", "gene_name": "PFDN1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPLDLELKKAFTELQAKVIDTQQKVKLADIQIEQLSKTKKHAHLTDTEIMTLVDETRMYEGVGRMFILQSKGVIHNQLLEKQRIAEEKIKELEQKKSYLERSVKEAEDNIREMLMARRAQ", "length": 122 }, "evidence": [ { "id": "A0A8C2MTB7", "url": "https://omabrowser.org/oma/group/A0A8C2MTB7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O60925-1", "protein_name": "Prefoldin 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"tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEILDKQAFFETREKLYTLSRSLNIIKQRIQIAENDRKKCLITINELESLSSETKTYKAVGKMFVISPMTSLKTELKQQVQKDEEDVKGLINQSKYIDAQITDTERSLNELVRKK", "length": 115 }, "evidence": [ { "id": "A0A8C2MTB7", "url": "https://omabrowser.org/oma/group/A0A8C2MTB7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5D016-1", "protein_name": "Prefoldin subunit 1", "gene_name": "pfdn1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAPVDLELKKAFAELQAKMVDTQQKVKLADLQIEQLSRVKKHANLTHGEITSLPESTRMFEGAGRMFILQSKGEISNQLLEKQKTADDKIKELEQKKTYLERSVKDAEDNIREMLMSRRAQ", "length": 122 }, "evidence": [ { "id": "A0A8C2MTB7", "url": "https://omabrowser.org/oma/group/A0A8C2MTB7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q94AF7-1", "protein_name": "Prefoldin subunit 1", "gene_name": "PFD1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADEATRAAFMEIQASMIELTGKLKQVQNQMRNKEGDRKRAFLTLEELRPLPEETNTYKSIGRTFVLEPKTVLEGEQEQKLKDSEAAVASLQTSKEYLEKQVAEVENNLRELLQQEPGIAQQIMSMSM", "length": 128 }, "evidence": [ { "id": "A0A8C2MTB7", "url": "https://omabrowser.org/oma/group/A0A8C2MTB7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VMH8-1", "protein_name": "Prefoldin 1, isoform A", "gene_name": "Pfdn1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAQMDIELKKAFTEMQINKLETTKKIHMIDMKCDMVKTGKQKYQLTEKGTSSLADDTRVYQSVGRMFLLTDVQNMREDLKARQEKCDKAIELLEKKKEFLQKSLKSQEDGLRELVQQRKEADQTAK", "length": 126 }, "evidence": [ { "id": "A0A8C2MTB7", "url": "https://omabrowser.org/oma/group/A0A8C2MTB7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { 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"A0A8C2MTB8_CRIGR", "mass": { "chemical_mass": 24036.0, "monoisotopic_mass": 24036.0 }, "refseq": { "ac": "XP_003499599", "name": "homeobox protein Hox-B7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499599" }, "gene_names": [ { "name": "Hoxb7", "type": "recommended", "evidence": [ { "id": "A0A8C2MTB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8" } ] }, { "name": "Hoxb7", "type": "synonym", "evidence": [ { "id": "XP_003499599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499599" } ] } ], "protein_names": [ { "name": "Homeobox protein Hox-B7", "type": "recommended", "evidence": [ { "id": "A0A8C2MTB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8/entry#names_and_taxonomy" } ] }, { "name": "homeobox protein Hox-B7", "type": "synonym", "evidence": [ { "id": "XP_003499599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499599" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613745.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003499599", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499599" } ] }, { "annotation": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTB8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8#function" }, { "database": "UniProtKB", "id": "ARBA00003263", "url": "https://www.uniprot.org/uniprotkb/ARBA00003263#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTB8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Hoxb7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8", "locus": {} } ], "crossref": [ { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774273", "url": "https://www.ncbi.nlm.nih.gov/gene/100774273", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774273", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774273", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QNCNKTD", "url": "https://omabrowser.org/oma/group/QNCNKTD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MTB8", "url": "https://www.orthodb.org/?gene=A0A8C2MTB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45659", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45659", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45659:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45659:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003499599", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499599", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MTB8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MTB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSLYYANALFSKYPAASSVFAPGAFPEQTSCAFASNPQRPGYGAGPGAPFSASVQTLYPGGGGMAGQSAPGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDPAKAAGAKEQRDSDLAAESNFRIYPWMRSSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTSGQGVTGQDKAEAEEEEEE", "length": 217, "header": "tr|A0A8C2MTB8-1|A0A8C2MTB8_CRIGR Isoform 1 of Homeobox protein Hox-B7 OS=Cricetulus griseus OX=10029 GN=Hoxb7 PE=3 SV=1 CANONICAL=A0A8C2MTB8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MTB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8/entry#A0A8C2MTB8-1", "sequence": { "sequence": "MSSLYYANALFSKYPAASSVFAPGAFPEQTSCAFASNPQRPGYGAGPGAPFSASVQTLYPGGGGMAGQSAPGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDPAKAAGAKEQRDSDLAAESNFRIYPWMRSSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTSGQGVTGQDKAEAEEEEEE", "length": 217, "header": "tr|A0A8C2MTB8-1|A0A8C2MTB8_CRIGR Isoform 1 of Homeobox protein Hox-B7 OS=Cricetulus griseus OX=10029 GN=Hoxb7 PE=3 SV=1 CANONICAL=A0A8C2MTB8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTB8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTB8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774273", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774273", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PE06-1", "protein_name": "Homeobox B7", "gene_name": "HOXB7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSLYYANALFSKYQAASSVFPSGVFPEQTSCAFASNTQRAGYGAGSTPPFASSMPGLYSSGSAVHPQPPGMYSSGYGLEPGSFNMHCSPFEQNLSMMCPGDASKQNCNKTDQRDSDLQSDSNFRIYPWMRSTGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTACSGSSSQEKADVEDDEEE", "length": 217 }, "evidence": [ { "id": "A0A8C2MTB8", "url": "https://omabrowser.org/oma/group/A0A8C2MTB8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1N1K1-1", "protein_name": "Homeobox protein Hox-B7", "gene_name": "HOXB7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSLYYANALFSKYPAASSVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAASMQGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAAESNFRIYPWMRSSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTSGPGAASQDKAEMEEDEEE", "length": 217 }, "evidence": [ { "id": "A0A8C2MTB8", "url": "https://omabrowser.org/oma/group/A0A8C2MTB8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RWG2-1", "protein_name": "Homeobox protein Hox-B7", "gene_name": "HOXB7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSLYYANALFSKYPAASSVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAASMQGLYPGGGGMAGQSTAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAAESNFRIYPWMRSSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTAGPRATSQDKAEAEEDEEE", "length": 217 }, "evidence": [ { "id": "A0A8C2MTB8", "url": "https://omabrowser.org/oma/group/A0A8C2MTB8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P09024-1", "protein_name": "Homeobox protein Hox-B7", "gene_name": "Hoxb7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLYYANALFSKYPAASSVFAPGAFPEQTSCAFASNPQRPGYGAGPGAPFSASVQGLYSGGGAMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDPAKAAGAKEQRDSDLAAESNFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKENKTSGPGTTGQDKAEAEEEEEE", "length": 217 }, "evidence": [ { "id": "A0A8C2MTB8", "url": "https://omabrowser.org/oma/group/A0A8C2MTB8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P09629-1", "protein_name": "Homeobox protein Hox-B7", "gene_name": "HOXB7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSLYYANTLFSKYPASSSVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAASMQGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAAESNFRIYPWMRSSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKENKTAGPGTTGQDRAEAEEEEEE", "length": 217 }, "evidence": [ { "id": "A0A8C2MTB8", "url": "https://omabrowser.org/oma/group/A0A8C2MTB8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P18864-1", "protein_name": "Homeobox protein Hox-B7", "gene_name": "Hoxb7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSLYYANALFSKYPAASSVFAPGAFPEQTSCAFASNPQRPGYGAGPGAPFSASVQGLYSGGGGMAGQSAAGVYEAGYGLEPSSFNMHCAPFEQNLSGVCPGDPAKAAGAKEQRDSDLAAESNFRIYPWMRSSGTERKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTSGPGTTGQDKAEADEEEEEEE", "length": 219 }, "evidence": [ { "id": "A0A8C2MTB8", "url": "https://omabrowser.org/oma/group/A0A8C2MTB8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTB8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTB8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8" } ], "pmid": "" }, { "name": "positive regulation of branching involved in ureteric bud morphogenesis", "id": "GO:0090190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090190", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTB8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8" } ], "pmid": "" }, { "name": "embryonic skeletal system morphogenesis", "id": "GO:0048704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048704", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTB8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTB8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTB8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTB8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MTB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTB8" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 135, "end_pos": 195, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 196, "end_pos": 198 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MTC5-1", "uniprot_ac": "A0A8C2MTC5", "uniprot_id": "A0A8C2MTC5_CRIGR", "mass": { "chemical_mass": 225191.0, "monoisotopic_mass": 225191.0 }, "refseq": { "ac": "XP_035301560", "name": "kinesin-like protein KIF26B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301560" }, "gene_names": [ { "name": "Kif26b", "type": "recommended", "evidence": [ { "id": "A0A8C2MTC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTC5" } ] }, { "name": "Kif26b", "type": "synonym", "evidence": [ { "id": "XP_035301560", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301560" } ] } ], "protein_names": [ { "name": "Kinesin-like protein KIF26B", "type": "synonym", "evidence": [ { "id": "A0A8C2MTC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTC5/entry#names_and_taxonomy" } ] }, { "name": "kinesin-like protein KIF26B", "type": "synonym", "evidence": [ { "id": "XP_035301560", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301560" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301560", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301560" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTC5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTC5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Kif26b", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTC5", "locus": {} } ], "crossref": [ { "id": "cd00106", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00106", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764244", "url": "https://www.ncbi.nlm.nih.gov/gene/100764244", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057090", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764244", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764244", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MTC5", "url": "https://www.orthodb.org/?gene=A0A8C2MTC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21608", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21608", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21608:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21608:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23081", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23081", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035301560", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301560", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MTC5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MTC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTC5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSVAGNKERLAVSTRGKKYGVNEVCSPTKPAAPFSPESWYRKAYEESRTGSRPTPEGAGSALGSSGTPSPGSGTSSPSSFTGSPGPASPGIGTSSPGSLGGSPGFGTGSPGSGSGGGSSPGSDRGVWCENCNARLVELKRQALKLLLPGPLPGKDPAFSAVIHDKLQVPNTIRKSWNDRDNRCDICATHLNQLKQEAIQMVLTLEQAAGSEHYDASLGSPPPISSIPTLVGSRHVGGLQQPREWAFVPAPYATSTYTGLVNKHSGKPNSLGVSNGAEKKGGSPTHQAKVSLQMATSPSNGNILNSVAIQAHQYLDGTWSLSRTNGVTLYPYQISQLMTETGREGLTESALNRYNADKPAASSVPASQASCVASETSTGTSVAASFFARAAQKLNLSSKKKKHRPSTASAAEAPLFATSFSGILQTSPPPAPPCLLRAVNKVKDTPGMGKVKVMLRICSTSARDTSESSSFLKVDPRKKQITLYDPLTCGGQNAFQKRSSQVPPKMFAFDAVFPQDASQAEVCAGTVAEVIQSVVNGADGCVFCFGHAKLGKSYTMIGRDDSMQNLGIIPCAISWLFKLINERKEKTGARFSVRISAVEVWGKEENLRDLLSEVATGSLQDGQSPGVYLCEDPICGTQLQNQSELRAPTAEKAAFFLDAAIASRRSNQQDCDEDDHRNSHMLFTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCVKALSKNREGGSGLCLSLSALGNVILALVNGSKHIPYKESKLTMLLRESLGNVNCRTTMIAHISAAAGSYTETLSTIQIASRVLRMKKKKTKYTSSSSGGESSCEEGRMRRPTQLRPFHARASVDPEFPLAPLSSDPDYSSSSEQSCDTVIYIGPNGTALSDKELTDNEGPPDFVPIVPALQKTRGDSRPAEAAEAAANKSERDCLKCNTFAELQERLDCIDGSDEPSRFPFEELPIQFAPAQAGGCVSLSQAAGPDPLSESDKEDNASDSGQLTTDRESTEIPASKVQPNRSPVPTVTHSSSPSPASPRSIPGSSSQHSASQLSQSPSLQSSRESLNSCGFVEGKPRPMGSPRLGIASLSKTSEYKPPSSPSQRCKVYTQKGVLPSSAPPPSLSKDSGMVSSESLLQPDVRTPPVGMSPQILKKSVSAGSEGFPGTLVEDEHQEGPPADSKKEILSTTMVTVQQPLELNGEDELVFTLVEELTISGVLDSGRPTSIISFNSDCSVQALASGSRPVSIISSISEDLECYSSMAPVSEVSITQFLPLPKLGLDEKAREAGSRRSSISSWLSEMSAGSDGEQSCHSFIAQTCFGHGEAMAEPPASEFVNTIQNTAVVCREKPEMGSDNLLILSEMGEEPVSKATPIKGCKISTVGKAMVTISNAANLSSCEGYIPMKTNITVYPCIAMSPRNVQEPESSTATPKAAPKTTQSQESKEANARREMKFEDPWLKREEEVKKETTSPGEEGARCETATSSLTTEVKTEQEQNGRPSSGDRLSNSSGEASAFQVTDSIRRVVDGCEMALSGLVTQSPIHSNKNLKSSSLPRAFQKADRHEALDSFYHCLADSNGFSGALGIQSSKTTLERKVASPKHCVLARPKGTPPLPPVRKSSLDQKNRASPQHSGSSSSTSSPLNQPATFLACFPEESNSKTKDASSSSKLFSAKLEQLASRTNSLGRTTVSHYECLSLERAESLSSVSSRMHASKDSTMPRTGRSLGRSTGASPPSCGITQSAGASPKASQSKISAVSKLLLASPKSRSLSTSTTKTLSFSTKSLPQSVGQSSNLPPSGKHMSWSTQSLSRNRGSGLASKLPLRAVNGRISELLQGSAGPRGAQLRAEAEERGGAPAEDKPSAAHLLPSPYSKITPPRKPHRCSSGHGSDNSSVLSGELPPAMGKTALFYHSGGSSGYESMMRDSEATGSASSAQDSMSENSSSVGGRCRSLKTPKKRSNSGSQRRRLIPALSLDTPSPVRKTASSTGVRWVDGPLRSTQRGLGEPFEIKVYEIDDVERLQRRRGGASKEVICFNAKLKILEHRQQRIAEVRAKYEWLMKELEATKQYLMLDPNKWLREFDLEQVLQLDSLEYLEALEGVTERLESRVNFCKAHLMMVTCFDITSRRR", "length": 2112, "header": "tr|A0A8C2MTC5-1|A0A8C2MTC5_CRIGR Isoform 1 of Kinesin-like protein KIF26B OS=Cricetulus griseus OX=10029 GN=Kif26b PE=3 SV=1 CANONICAL=A0A8C2MTC5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MTC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTC5/entry#A0A8C2MTC5-1", "sequence": { "sequence": "MNSVAGNKERLAVSTRGKKYGVNEVCSPTKPAAPFSPESWYRKAYEESRTGSRPTPEGAGSALGSSGTPSPGSGTSSPSSFTGSPGPASPGIGTSSPGSLGGSPGFGTGSPGSGSGGGSSPGSDRGVWCENCNARLVELKRQALKLLLPGPLPGKDPAFSAVIHDKLQVPNTIRKSWNDRDNRCDICATHLNQLKQEAIQMVLTLEQAAGSEHYDASLGSPPPISSIPTLVGSRHVGGLQQPREWAFVPAPYATSTYTGLVNKHSGKPNSLGVSNGAEKKGGSPTHQAKVSLQMATSPSNGNILNSVAIQAHQYLDGTWSLSRTNGVTLYPYQISQLMTETGREGLTESALNRYNADKPAASSVPASQASCVASETSTGTSVAASFFARAAQKLNLSSKKKKHRPSTASAAEAPLFATSFSGILQTSPPPAPPCLLRAVNKVKDTPGMGKVKVMLRICSTSARDTSESSSFLKVDPRKKQITLYDPLTCGGQNAFQKRSSQVPPKMFAFDAVFPQDASQAEVCAGTVAEVIQSVVNGADGCVFCFGHAKLGKSYTMIGRDDSMQNLGIIPCAISWLFKLINERKEKTGARFSVRISAVEVWGKEENLRDLLSEVATGSLQDGQSPGVYLCEDPICGTQLQNQSELRAPTAEKAAFFLDAAIASRRSNQQDCDEDDHRNSHMLFTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCVKALSKNREGGSGLCLSLSALGNVILALVNGSKHIPYKESKLTMLLRESLGNVNCRTTMIAHISAAAGSYTETLSTIQIASRVLRMKKKKTKYTSSSSGGESSCEEGRMRRPTQLRPFHARASVDPEFPLAPLSSDPDYSSSSEQSCDTVIYIGPNGTALSDKELTDNEGPPDFVPIVPALQKTRGDSRPAEAAEAAANKSERDCLKCNTFAELQERLDCIDGSDEPSRFPFEELPIQFAPAQAGGCVSLSQAAGPDPLSESDKEDNASDSGQLTTDRESTEIPASKVQPNRSPVPTVTHSSSPSPASPRSIPGSSSQHSASQLSQSPSLQSSRESLNSCGFVEGKPRPMGSPRLGIASLSKTSEYKPPSSPSQRCKVYTQKGVLPSSAPPPSLSKDSGMVSSESLLQPDVRTPPVGMSPQILKKSVSAGSEGFPGTLVEDEHQEGPPADSKKEILSTTMVTVQQPLELNGEDELVFTLVEELTISGVLDSGRPTSIISFNSDCSVQALASGSRPVSIISSISEDLECYSSMAPVSEVSITQFLPLPKLGLDEKAREAGSRRSSISSWLSEMSAGSDGEQSCHSFIAQTCFGHGEAMAEPPASEFVNTIQNTAVVCREKPEMGSDNLLILSEMGEEPVSKATPIKGCKISTVGKAMVTISNAANLSSCEGYIPMKTNITVYPCIAMSPRNVQEPESSTATPKAAPKTTQSQESKEANARREMKFEDPWLKREEEVKKETTSPGEEGARCETATSSLTTEVKTEQEQNGRPSSGDRLSNSSGEASAFQVTDSIRRVVDGCEMALSGLVTQSPIHSNKNLKSSSLPRAFQKADRHEALDSFYHCLADSNGFSGALGIQSSKTTLERKVASPKHCVLARPKGTPPLPPVRKSSLDQKNRASPQHSGSSSSTSSPLNQPATFLACFPEESNSKTKDASSSSKLFSAKLEQLASRTNSLGRTTVSHYECLSLERAESLSSVSSRMHASKDSTMPRTGRSLGRSTGASPPSCGITQSAGASPKASQSKISAVSKLLLASPKSRSLSTSTTKTLSFSTKSLPQSVGQSSNLPPSGKHMSWSTQSLSRNRGSGLASKLPLRAVNGRISELLQGSAGPRGAQLRAEAEERGGAPAEDKPSAAHLLPSPYSKITPPRKPHRCSSGHGSDNSSVLSGELPPAMGKTALFYHSGGSSGYESMMRDSEATGSASSAQDSMSENSSSVGGRCRSLKTPKKRSNSGSQRRRLIPALSLDTPSPVRKTASSTGVRWVDGPLRSTQRGLGEPFEIKVYEIDDVERLQRRRGGASKEVICFNAKLKILEHRQQRIAEVRAKYEWLMKELEATKQYLMLDPNKWLREFDLEQVLQLDSLEYLEALEGVTERLESRVNFCKAHLMMVTCFDITSRRR", "length": 2112, "header": "tr|A0A8C2MTC5-1|A0A8C2MTC5_CRIGR Isoform 1 of Kinesin-like protein KIF26B OS=Cricetulus griseus OX=10029 GN=Kif26b PE=3 SV=1 CANONICAL=A0A8C2MTC5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 55, "start_aa": "Thr", "end_pos": 55, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr55", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTC5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTC5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTC5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTC5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764244", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764244", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTC5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTC5" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTC5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTC5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTC5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTC5" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTC5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTC5" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTC5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTC5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1006, "end_pos": 1008, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1379, "end_pos": 1381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1392, "end_pos": 1394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1493, "end_pos": 1495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1875, "end_pos": 1877, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1925, "end_pos": 1927, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 641, "end_pos": 643, "annotation": "n_glycosylation_sequon" }, { "start_pos": 745, "end_pos": 747, "annotation": "n_glycosylation_sequon" }, { "start_pos": 871, "end_pos": 873, "annotation": "n_glycosylation_sequon" }, { "start_pos": 914, "end_pos": 916, "annotation": "n_glycosylation_sequon" }, { "start_pos": 982, "end_pos": 984, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MTC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTC5" }, { "id": "PS50067", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50067" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kinesin motor", "eco_id": "ECO_0000259", "start_pos": 450, "end_pos": 801, "start_aa": "Lys", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 55, 68 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1006, "end_pos": 1008 }, { "start_pos": 1379, "end_pos": 1381 }, { "start_pos": 1392, "end_pos": 1394 }, { "start_pos": 1493, "end_pos": 1495 }, { "start_pos": 1875, "end_pos": 1877 }, { "start_pos": 1925, "end_pos": 1927 }, { "start_pos": 395, "end_pos": 397 }, { "start_pos": 641, "end_pos": 643 }, { "start_pos": 745, "end_pos": 747 }, { "start_pos": 871, "end_pos": 873 }, { "start_pos": 914, "end_pos": 916 }, { "start_pos": 982, "end_pos": 984 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 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"MPDTNQGWPEDFGFQLGGSGPCFVMEVAEGSSAHAGGLRPGDQILEVEGLAVGGLSREHLVRLARRCPRVPPSLGVLPGPEGGPTALTAAWLSPRFGGRLPLGRELLRLAGRRRPDAVHRERRRKAQEFSCKVDDILGDQPTAKEQVFAALKQFAAEQQVDELVWALTLVLPSEAQGPVLDNLRIFIPKKHRARFDEVVSQGLLGKLCRARRAQGAQRLRRSRSEERPERLLVSTRASAAPRRPDEPPPRKAASLLGGRTGPGGPRRTVRVYKGNKSFGFTLRGHGPVWIESVLPGSPAESASLKSGDRILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGPVPFASDSDSLDSPTRSSALTSLQWVADILPSSIRVQGRTFSQQLDHLLTPPERYGVCRALESFFQHRNIDTLIVDVYPVLDTPAKQVLWQFLYQLLTYEEQELCQEKIARFLGYTAMTEPESSLDLEPESTPEPTPEPQPRSSQRASSMCRRSLRSQSLEASLSCGPGDCPEMPLPLIPGERQAGDGTSLPETPNPKMMSAVYAELESRLNSSFKGKIGTVSKSRASPPVPSLVGTAGPRTLSGVSWPSERLLPSPCYDPLCSGGLASPSSSESHPYASLDSSRAPSPQPGLGSIHPDSPPSPEPIRPPSRRKLFAFSRPVRSRDTDRFLDVLSEQLGPRVTIVDDFLTPENDYEEMSFHDDQGSFVTNERSSASDCVSSSEEGSSLTYSSISDHIPPPPLSPPPPPPLPFHDPKPSSRTSDGPRGPPQSLTKPLNQLSHPVPPPPPPPLPPPVPCAPPMLSRGMGHRRSETSHMSVKRLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPSKPVPGPEPFRKKEVVEILSHKKAYNTSILLAHLKLTPGELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAFREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVLAMGNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLPTVPLAAKVNQRALTGDLADLHGTVSEIQVACQSMSPSSEDRFAVVMSSFLETAQPALRALDGLQREAMEELGKALAFFGEDSKATTSEAFFGIFSEFMNKFERALSDLQAGDGPRSSGMVSPLAW", "length": 1203, "header": "tr|A0A8C2MTT1-1|A0A8C2MTT1_CRIGR Isoform 1 of Delphilin OS=Cricetulus griseus OX=10029 GN=Grid2ip PE=4 SV=1 CANONICAL=A0A8C2MTT1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MTE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTT1/entry#A0A8C2MTE1-1", "sequence": { "sequence": "MSCLGIFIPKKHRARFDEVVSQGLLGKLCRARRAQGAQRLRRSRSEERPERLLVSTRASAAPRRPDEPPPRKAASLLGGRTGPGGPRRTVRVYKGNKSFGFTLRGHGPVWIESVLPGSPAESASLKSGDRILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGPVPFASDSDSLDSPTRSSALTSLQWVADILPSSIRVQGRTFSQQLDHLLTPPERYGVCRALESFFQHRNIDTLIVDVYPVLDTPAKQVLWQFLYQLLTYEEQELCQEKIARFLGYTAMTEPESSLDLEPESTPEPTPEPQPRSSQRASSMCRRSLRSQSLEASLSCGPGDCPEMPLPLIPGERQAGDGTSLPETPNPKMMSAVYAELESRLNSSFKGKIGTVSKSRASPPVPSLVGTAGPRTLSGVSWPSERLLPSPCYDPLCSGGLASPSSSESHPYASLDSSRAPSPQPGLGSIHPDSPPSPEPIRPPSRRKLFAFSRPVRSRDTDRFLDVLSEQLGPRVTIVDDFLTPENDYEEMSFHDDQGSFVTNERSSASDCVSSSEEGSSLTYSSISDHIPPPPLSPPPPPPLPFHDPKPSSRTSDGPRGPPQSLTKPLNQLSHPVPPPPPPPLPPPVPCAPPMLSRGMGHRRSETSHMSVKRLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPSKPVPGPEPFRKKEVVEILSHKKAYNTSILLAHLKLTPGELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAFREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVLAMGNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLPTVPLAAKVNQRALTGDLADLHGTVSEIQVACQSMSPSSEDRFAVVMSSFLETAQPALRALDGLQREAMEELGKALAFFGEDSKATTSEAFFGIFSEFMNKFERALSDLQAGDGPRSSGMVSPLAW", "length": 1024, "header": "tr|A0A8C2MTE1-1|A0A8C2MTT1_CRIGR Computationally mapped isoform of Delphilin OS=Cricetulus griseus OX=10029 GN=Grid2ip PE=4 SV=1 CANONICAL=A0A8C2MTT1-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MTT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTT1/entry#A0A8C2MTT1-1", "sequence": { "sequence": "MPDTNQGWPEDFGFQLGGSGPCFVMEVAEGSSAHAGGLRPGDQILEVEGLAVGGLSREHLVRLARRCPRVPPSLGVLPGPEGGPTALTAAWLSPRFGGRLPLGRELLRLAGRRRPDAVHRERRRKAQEFSCKVDDILGDQPTAKEQVFAALKQFAAEQQVDELVWALTLVLPSEAQGPVLDNLRIFIPKKHRARFDEVVSQGLLGKLCRARRAQGAQRLRRSRSEERPERLLVSTRASAAPRRPDEPPPRKAASLLGGRTGPGGPRRTVRVYKGNKSFGFTLRGHGPVWIESVLPGSPAESASLKSGDRILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGPVPFASDSDSLDSPTRSSALTSLQWVADILPSSIRVQGRTFSQQLDHLLTPPERYGVCRALESFFQHRNIDTLIVDVYPVLDTPAKQVLWQFLYQLLTYEEQELCQEKIARFLGYTAMTEPESSLDLEPESTPEPTPEPQPRSSQRASSMCRRSLRSQSLEASLSCGPGDCPEMPLPLIPGERQAGDGTSLPETPNPKMMSAVYAELESRLNSSFKGKIGTVSKSRASPPVPSLVGTAGPRTLSGVSWPSERLLPSPCYDPLCSGGLASPSSSESHPYASLDSSRAPSPQPGLGSIHPDSPPSPEPIRPPSRRKLFAFSRPVRSRDTDRFLDVLSEQLGPRVTIVDDFLTPENDYEEMSFHDDQGSFVTNERSSASDCVSSSEEGSSLTYSSISDHIPPPPLSPPPPPPLPFHDPKPSSRTSDGPRGPPQSLTKPLNQLSHPVPPPPPPPLPPPVPCAPPMLSRGMGHRRSETSHMSVKRLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPSKPVPGPEPFRKKEVVEILSHKKAYNTSILLAHLKLTPGELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAFREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVLAMGNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLPTVPLAAKVNQRALTGDLADLHGTVSEIQVACQSMSPSSEDRFAVVMSSFLETAQPALRALDGLQREAMEELGKALAFFGEDSKATTSEAFFGIFSEFMNKFERALSDLQAGDGPRSSGMVSPLAW", "length": 1203, "header": "tr|A0A8C2MTT1-1|A0A8C2MTT1_CRIGR Isoform 1 of Delphilin OS=Cricetulus griseus OX=10029 GN=Grid2ip PE=4 SV=1 CANONICAL=A0A8C2MTT1-1" }, "locus": {} }, { "isoform_ac": "A0A8C2QMM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTT1/entry#A0A8C2QMM3-1", "sequence": { "sequence": "MGKDQGFSRHFRIFIPKKHRARFDEVVSQGLLGKLCRARRAQGAQRLRRSRSEERPERLLVSTRASAAPRRPDEPPPRKAASLLGGRTGPGGPRRTVRVYKGNKSFGFTLRGHGPVWIESVLPGSPAESASLKSGDRILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGPVPFASDSDSLDSPTRSSALTSLQWVADILPSSIRVQGRTFSQQLDHLLTPPERYGVCRALESFFQHRNIDTLIVDVYPVLDTPAKQVLWQFLYQLLTYEEQELCQEKIARFLGYTAMTEPESSLDLEPESTPEPTPEPQPRSSQRASSMCRRSLRSQSLEASLSCGPGDCPEMPLPLIPGERQAGDGTSLPETPNPKMMSAVYAELESRLNSSFKGKIGTVSKSRASPPVPSLVGTAGPRTLSGVSWPSERLLPSPCYDPLCSGGLASPSSSESHPYASLDSSRAPSPQPGLGSIHPDSPPSPEPIRPPSRRKLFAFSRPVRSRDTDRFLDVLSEQLGPRVTIVDDFLTPENDYEEMSFHDDQGSFVTNERSSASDCVSSSEEGSSLTYSSISDHIPPPPLSPPPPPPLPFHDPKPSSRTSDGPRGPPQSLTKPLNQLSHPVPPPPPPPLPPPVPCAPPMLSRGMGHRRSETSHMSVKRLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPSKPVPGPEPFRKKEVVEILSHKKAYNTSILLAHLKLTPGELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAFREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVLAMGNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLPTVPLAAKVNQRALTGDLADLHGTVSEIQVACQSMSPSSEDRFAVVMSSFLETAQPALRALDGLQREAMEELGKALAFFGEDSKATTSEAFFGIFSEFMNKFERALSDLQAGDGPRSSGMVSPLAW", "length": 1031, "header": "tr|A0A8C2QMM3-1|A0A8C2MTT1_CRIGR Computationally mapped isoform of Delphilin OS=Cricetulus griseus OX=10029 GN=Grid2ip PE=4 SV=1 CANONICAL=A0A8C2MTT1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 480, "start_aa": "Thr", "end_pos": 480, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr480", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTE1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTE1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTE1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTE1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766186", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766186", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTT1" } ], "pmid": "" }, { "name": "postsynaptic density, intracellular component", "id": "GO:0099092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099092", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTT1" } ], "pmid": "" }, { "name": "parallel fiber to Purkinje cell synapse", "id": "GO:0098688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098688", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTT1" } ], "pmid": "" }, { "name": "cerebellar granule cell to Purkinje cell synapse", "id": "GO:0150048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150048", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTT1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of postsynaptic membrane neurotransmitter receptor levels", "id": "GO:0099072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099072", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTT1" } ], "pmid": "" }, { "name": "regulation of postsynaptic cytosolic calcium ion concentration", "id": "GO:0099566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099566", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1030, "end_pos": 1032, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1044, "end_pos": 1046, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" }, { "start_pos": 894, "end_pos": 896, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MTT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTT1" }, { "id": "PS51444", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51444" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FH2", "eco_id": "ECO_0000259", "start_pos": 812, "end_pos": 1203, "start_aa": "His", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MTT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTT1" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 66, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 480 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1030, "end_pos": 1032 }, { "start_pos": 1044, "end_pos": 1046 }, { "start_pos": 275, "end_pos": 277 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 556, "end_pos": 558 }, { "start_pos": 894, "end_pos": 896 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MTG4-1", "uniprot_ac": "A0A8C2MTG4", "uniprot_id": "A0A8C2MTG4_CRIGR", "mass": { "chemical_mass": 29248.0, "monoisotopic_mass": 29248.0 }, "refseq": { "ac": "XP_027264944", "name": "phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264944" }, "gene_names": [ { "name": "Lhpp", "type": "recommended", "evidence": [ { "id": "A0A8C2MTG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTG4" } ] }, { "name": "Lhpp", "type": "synonym", "evidence": [ { "id": "XP_027264944", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264944" } ] } ], "protein_names": [ { "name": "Phospholysine phosphohistidine inorganic pyrophosphate phosphatase", "type": "recommended", "evidence": [ { "id": "A0A8C2MTG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTG4/entry#names_and_taxonomy" } ] }, { "name": 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027264944", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264944" } ] }, { "annotation": "Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. 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"UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDYGFGVLVQSNTGNKSAFPVRFHPHLQPPHHHQNATPNPAAFINNNTAANGSSAGSAWLFPAPATHNIQDEILGSEKGKSQQQEQQDPLEKQQLSPSPGQEAGILPETEKAKAEENPGDNSSENSNGKEKIRIESPVLTGFDYQEATGLGTSTQPLTSSASSLTGFSNWSAAIAPSSSTIINEDASFFHQGGVPGASANNGALLFQNFPHHVSPGFGGSFSPQIGPLSQHHPHHPHFQHHHSQHQQQRRSPASPHPPPFTHRNAAFNQLPHLANNLNKPPSPWSSYQSPSPTPSSSWSPGGGGYGGWGASQGRDHRRGLNGGITPLNSISPLKKNFASNHIQLQKYARPSSAFAPKSWMEDSLNRADTIFPFPDRPRTFDMHSLESSLIDIMRAENDSIKGRLNYSYPGSDSSLLINGQSSLFPMEDGFLDDGRGDQPLHSGLGSPHCFTHQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGEIDKRVEVKPYVLDDQLCDECQGARCGGKFAPFFCANVTCLQYYCEYCWAAIHSRAGREFHKPLVKEGGDRPRHISFRWN", "length": 721, "header": "tr|A0A8C2MTM8-1|A0A8C2MTM8_CRIGR Isoform 1 of Cytoplasmic polyadenylation element-binding protein 4 isoform X1 OS=Cricetulus griseus OX=10029 GN=Cpeb4 PE=3 SV=1 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element-binding protein 4 isoform X1 OS=Cricetulus griseus OX=10029 GN=Cpeb4 PE=3 SV=1 CANONICAL=A0A8C2MTM8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GB72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTM8/entry#A0A9J7GB72-1", "sequence": { "sequence": "MGDYGFGVLVQSNTGNKSAFPVRFHPHLQPPHHHQNATPNPAAFINNNTAANGSSAGSAWLFPAPATHNIQDEILGSEKGKSQQQEQQDPLEKQQLSPSPGQEAGILPETEKAKAEENPGDNSSENSNGKEKIRIESPVLTGFDYQEATGLGTSTQPLTSSASSLTGFSNWSAAIAPSSSTIINEDASFFHQGGVPGASANNGALLFQNFPHHVSPGFGGSFSPQIGPLSQHHPHHPHFQHHHSQHQQQRRSPASPHPPPFTHRNAAFNQLPHLANNLNKPPSPWSSYQSPSPTPSSSWSPGGGGYGGWGASQGRDHRRGLNGGITPLNSISPLKKNFASNHIQLQKYARPSSAFAPKSWMEDSLNRADTIFPFPDRPRTFDMHSLESSLIDIMRAENDSIKGQSSLFPMEDGFLDDGRGDQPLHSGLGSPHCFTHQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGEIDKRVEVKPYVLDDQLCDECQGARCGGKFAPFFCANVTCLQYYCEYCWAAIHSRAGREFHKPLVKEGGDRPRHISFRWN", "length": 704, "header": "tr|A0A9J7GB72-1|A0A8C2MTM8_CRIGR Computationally mapped isoform of Cytoplasmic polyadenylation element-binding protein 4 isoform X1 OS=Cricetulus griseus OX=10029 GN=Cpeb4 PE=3 SV=1 CANONICAL=A0A8C2MTM8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 294, "start_aa": "Thr", "end_pos": 294, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr294", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027255271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255271" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Srsf4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP7", "locus": {} } ], "crossref": [ { "id": "cd12594", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12594", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12600", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12600", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762302", "url": "https://www.ncbi.nlm.nih.gov/gene/100762302", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762302", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762302", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MTP7", "url": "https://www.orthodb.org/?gene=A0A8C2MTP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48038", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48038", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48038:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48038:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027255271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255271", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MTP7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MTP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSHSRSKSRSRSQSRSRSKKEKSRSPSKDNKSRSRSRSADKTRSKSKDHAEDKLQNNDSAGKAKSRSPSRRDSKSRSRSKERRAEEKRRSVSRSRSQEKRRSQEKNLLKSRSRSRSKGGSRSRSRSKSKDKRKGRKRSREESRSRSRSKSERSRKHSSKRDSKGSSSKKKKDDTDHSRSPSRSVSKEREHTKAESGQREGRSEGESAGPHPEPRARSPSTSKSKPSLPAESRSRSKSASKTRSRSKSPSRSASRSPSRSRSRSHSRS", "length": 491, "header": "tr|A0A8C2MTP7-1|A0A8C2MTP7_CRIGR Isoform 1 of Serine/arginine-rich splicing factor 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Srsf4 PE=3 SV=1 CANONICAL=A0A8C2MTP7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MTP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP7/entry#A0A8C2MTP7-1", "sequence": { "sequence": "MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSHSRSKSRSRSQSRSRSKKEKSRSPSKDNKSRSRSRSADKTRSKSKDHAEDKLQNNDSAGKAKSRSPSRRDSKSRSRSKERRAEEKRRSVSRSRSQEKRRSQEKNLLKSRSRSRSKGGSRSRSRSKSKDKRKGRKRSREESRSRSRSKSERSRKHSSKRDSKGSSSKKKKDDTDHSRSPSRSVSKEREHTKAESGQREGRSEGESAGPHPEPRARSPSTSKSKPSLPAESRSRSKSASKTRSRSKSPSRSASRSPSRSRSRSHSRS", "length": 491, "header": "tr|A0A8C2MTP7-1|A0A8C2MTP7_CRIGR Isoform 1 of Serine/arginine-rich splicing factor 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Srsf4 PE=3 SV=1 CANONICAL=A0A8C2MTP7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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[ { "database": "UniProtKB", "id": "A0A8C2MTP7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP7" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP7" } ], "pmid": "" }, { "name": "negative regulation of mRNA splicing, via spliceosome", "id": "GO:0048025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048025", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 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"sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MTP9-1", "uniprot_ac": "A0A8C2MTP9", "uniprot_id": "A0A8C2MTP9_CRIGR", "mass": { "chemical_mass": 33772.0, "monoisotopic_mass": 33772.0 }, "refseq": { "ac": "XP_003497987", "name": "TBC1 domain family member 7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497987" }, "gene_names": [ { "name": "LOC100767925", "type": "recommended", "evidence": [ { "id": "A0A8C2MTP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9" } ] }, { "name": "LOC100767925", "type": "synonym", "evidence": [ { "id": "XP_003497987", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497987" } ] } ], "protein_names": [ { "name": "TBC1 domain family member 7", "type": "recommended", "evidence": [ { "id": "A0A8C2MTP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9/entry#names_and_taxonomy" } ] }, { "name": "TBC1 domain family member 7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003497987", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497987" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613670.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497987", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497987" } ] }, { "annotation": "Non-catalytic component of the TSC-TBC complex, a multiprotein complex that acts as a negative regulator of the canonical mTORC1 complex, an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth. The TSC-TBC complex acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. In absence of nutrients, the TSC-TBC complex inhibits mTORC1, thereby preventing phosphorylation of ribosomal protein S6 kinase (RPS6KB1 and RPS6KB2) and EIF4EBP1 (4E-BP1) by the mTORC1 signaling. The TSC-TBC complex is inactivated in response to nutrients, relieving inhibition of mTORC1.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUY7#function" }, { "database": "UniProtKB", "id": "ARBA00046045", "url": "https://www.uniprot.org/uniprotkb/ARBA00046045#function" }, { "database": "UniProtKB", "id": "A0A8C2MTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100767925", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9", "locus": {} } ], "crossref": [ { "id": "100767925", "url": 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"id": "A0A8C2MTP9", "url": "https://www.orthodb.org/?gene=A0A8C2MTP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13530", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13530", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13530:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13530:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003497987", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497987", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MTP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUY7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTDDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDPLDIEKLCTFSQRFPLPSMYRALVWKVLLGILPPHHDSHAQVMAYRKDQYSDVLHALTVVRFISDATPQVEVYLRMYQLESGKLPRSPSFPMEPEDEVFLAIAKAMEEMVEDSIDCYWLTRCFVKQLHSKFRDSLPQLPKAFEQYLNLEDSRLLSHLKTCSAVSKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSVEKITEFLENIPQDSSDAIVSKAIDLWHKHCGTPAHSA", "length": 293, "header": "tr|A0A8C2MTP9-1|A0A8C2MTP9_CRIGR Isoform 1 of TBC1 domain family member 7 OS=Cricetulus griseus OX=10029 GN=LOC100767925 PE=4 SV=1 CANONICAL=A0A8C2MTP9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MTP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9/entry#A0A8C2MTP9-1", "sequence": { "sequence": "MTDDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDPLDIEKLCTFSQRFPLPSMYRALVWKVLLGILPPHHDSHAQVMAYRKDQYSDVLHALTVVRFISDATPQVEVYLRMYQLESGKLPRSPSFPMEPEDEVFLAIAKAMEEMVEDSIDCYWLTRCFVKQLHSKFRDSLPQLPKAFEQYLNLEDSRLLSHLKTCSAVSKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSVEKITEFLENIPQDSSDAIVSKAIDLWHKHCGTPAHSA", "length": 293, "header": "tr|A0A8C2MTP9-1|A0A8C2MTP9_CRIGR Isoform 1 of TBC1 domain family member 7 OS=Cricetulus griseus OX=10029 GN=LOC100767925 PE=4 SV=1 CANONICAL=A0A8C2MTP9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FUY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9/entry#A0A9J7FUY7-1", "sequence": { "sequence": "MTDDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDPLDIEKLCTFSQRFPLPSMYRALVWKVLLGILPPHHDSHAQVMAYRKDQYSDVLHALTVVRFISDATPQVEVYLRMYQLESGKLPRSPSFPMPKAFEQYLNLEDSRLLSHLKTCSAVSKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSVEKITEFLENIPQDSSDAIVSKAIDLWHKHCGTPAHSA", "length": 247, "header": "tr|A0A9J7FUY7-1|A0A8C2MTP9_CRIGR Computationally mapped isoform of TBC1 domain family member 7 OS=Cricetulus griseus OX=10029 GN=LOC100767925 PE=4 SV=1 CANONICAL=A0A8C2MTP9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUY7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUY7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767925", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767925", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A809-1", "protein_name": "TBC1 domain family member 7", "gene_name": "TBC1D7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTDDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDIEKLCTFSQRFPLPSLYRALVWKVLLGILPPHHESHARVMAYRKEQYSDVLHALDVIRFVSDATPQVEVFLYMHRLESGKLPRSPSFPLEPEDEVFLAIAKAMEEMVEDSVDCYWITRCFVNQLDSKYRDFLPQLPKAFEQYLNLEDSRLLSHLKACSAVSRLPYDLWFKRCFAGCLPEPSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSA", "length": 293 }, "evidence": [ { "id": "A0A8C2MTP9", "url": "https://omabrowser.org/oma/group/A0A8C2MTP9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0M1L8-1", "protein_name": "TBC1 domain family member 7", "gene_name": "Tbc1d7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTDDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDVASWFLGKLKESRLWFPFVEDIEKLCTFSQRFPLPSMYRVLVWKVLLGILPPHHDSHAQVMAYRKDQYSDVLHALTVVRFISDATPQGEVYLRMYQLESGKLPRSPSFPLELEDEVFLAIAKAMEEMVEDSVDCYWITRCFVKQFNNKYRDALPQLPRAFEQYLNLEDSRLLSHLKTCSAVSKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSA", "length": 314 }, "evidence": [ { "id": "A0A8C2MTP9", "url": "https://omabrowser.org/oma/group/A0A8C2MTP9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QRX7-1", "protein_name": "TBC1 domain family member 7", "gene_name": "tbc1d7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADDPQRNFRSAYYEKVGFRGVEEKKSLEILLKDNPLDVEKLSTFSQRFPLPSMYRIHVWKVLLGILPPHSDSHALVRQYRVDQFEDVSCALTVMRFIHASTPQTEIYLRMFQLENHTLPRRTELRPPDAEDENFLAIARAMEEIVDDPVDCFWLVRCFINQFKHKFGDSIPHLPKSLEHFLSQEDVCLLSHLKASGALALLPYSLWFRRCFAGCLPESSLQRVWDKVISGSCKILVFVAVEILLSHKIVIMGMNQPDAIYHFLSNMPQENTDAIVTKAIDLWHKYCGTPMHSV", "length": 294 }, "evidence": [ { "id": "A0A8C2MTP9", "url": "https://omabrowser.org/oma/group/A0A8C2MTP9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5E9C4-1", "protein_name": "TBC1 domain family member 7", "gene_name": "TBC1D7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTEDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDIEKLCTFSQRFPLPSMYRALVWKVLLGILPPHHESHVQVMTYRKEQYSDVLHALKVIRFVSDATPQSEVYLYMHRLESGKLPRSPSFPLEPEDEVFLAIAKAMEEMVEDSVDCYWIMRCFVNQLNSKYRDTLPQLPKAFEQYLNLEDSRLLSHLKACCAVSTLPYELWFKKCFAGCLPESSLQRIWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSA", "length": 293 }, "evidence": [ { "id": "A0A8C2MTP9", "url": "https://omabrowser.org/oma/group/A0A8C2MTP9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D0K0-1", "protein_name": "TBC1 domain family member 7", "gene_name": "Tbc1d7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTDDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDIEKLCTFSQRFPLPSMYRALVWKALLGILPPHHDTHSQVMAYRKDQYHDILHALTVVRFISDATPQAEVYLRMYQLESGKLPRSPSFPLEPEDEVFLAIAKAMEEMVEDSVDCYWISRCFVKQLNNKYRDALPQLPKAFEQYLNLEDSRLLSHLKTCSAVSKLPYDLWFQRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSA", "length": 293 }, "evidence": [ { "id": "A0A8C2MTP9", "url": "https://omabrowser.org/oma/group/A0A8C2MTP9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P0N9-1", "protein_name": "TBC1 domain family member 7", "gene_name": "TBC1D7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDTEKLCTFSQRFPLPSMYRALVWKVLLGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEVYLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSS", "length": 293 }, "evidence": [ { "id": "A0A8C2MTP9", "url": "https://omabrowser.org/oma/group/A0A8C2MTP9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VCC4-1", "protein_name": "TBC1 domain family member 7", "gene_name": "TBC1d7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTDERNFRSIYYEKCQINSVEEQKSLNKLLQDDIRNLSKLKQFCMNYTVPNNNRSYLWALVMGILPLHKASTAYVRDQRREMYEDLRRAVTVLRFTDHKQKEQPFMWLIDHKKKAQVMHTMWLIESNRLWHGNTSASLQADDMHFIEIVRTLLQIFDDNVETYWIAKGFYKYTRELKKECVKLKEQTQNILKREDLSLLNHLELLGLFDGNSTLLDNWYITCFAGIICTTHLVKIWDKVCGGSRKIVVFLFVELVKDIRSSILKQTSLADVKRLIETVKDLDGVIIVNKAIKSLQNNSSEVEYTH", "length": 306 }, "evidence": [ { "id": "A0A8C2MTP9", "url": "https://omabrowser.org/oma/group/A0A8C2MTP9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "TSC1-TSC2 complex", "id": "GO:0033596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033596", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of cilium assembly", "id": "GO:1902018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902018", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9" } ], "pmid": "" }, { "name": "positive regulation of protein ubiquitination", "id": "GO:0031398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031398", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9" } ], "pmid": "" }, { "name": "response to growth factor", "id": "GO:0070848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070848", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9" } ], "pmid": "" }, { "name": "negative regulation of TOR signaling", "id": "GO:0032007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MTP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTP9" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 231, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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}, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MTQ3-1", "uniprot_ac": "A0A8C2MTQ3", "uniprot_id": "A0A8C2MTQ3_CRIGR", "mass": { "chemical_mass": 48733.0, "monoisotopic_mass": 48733.0 }, "refseq": { "ac": "XP_035303129", "name": "tektin-1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303129" }, "gene_names": [ { "name": "Tekt1", "type": "recommended", "evidence": [ { "id": "A0A8C2MTQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTQ3" } ] }, { "name": "Tekt1", "type": "synonym", "evidence": [ { "id": "XP_035303129", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303129" } ] } ], "protein_names": [ { "name": "Tektin", "type": "recommended", "evidence": [ { "id": "A0A8C2MTQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTQ3/entry#names_and_taxonomy" } ] }, { "name": "tektin-1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035303129", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303129" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303129", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303129" } ] }, { "annotation": "Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. 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This record is derived from a genomic sequence (NW_003613803.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007639619", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639619" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTT5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTT5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Higd1a", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTT5", "locus": {} } ], "crossref": [ { "id": "100766684", "url": "https://www.ncbi.nlm.nih.gov/gene/100766684", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007667", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007667", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766684", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766684", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MCKELWA", "url": "https://omabrowser.org/oma/group/MCKELWA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MTT5", "url": "https://www.orthodb.org/?gene=A0A8C2MTT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12297", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12297", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12297:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12297:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007639619", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639619", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MTT5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MTT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTDTDLSLSSYDEGQGSKFIRKTKETPFVPIGMAGFAAIVAYGLYKLKNRGNTKMSIHLIHMRVAAQGFVVGALTLGMGYSMYKEFWAKPKP", "length": 93, "header": "tr|A0A8C2MTT5-1|A0A8C2MTT5_CRIGR Isoform 1 of HIG1 domain family member 1A, mitochondrial OS=Cricetulus griseus OX=10029 GN=Higd1a PE=4 SV=1 CANONICAL=A0A8C2MTT5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MTT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTT5/entry#A0A8C2MTT5-1", "sequence": { "sequence": "MSTDTDLSLSSYDEGQGSKFIRKTKETPFVPIGMAGFAAIVAYGLYKLKNRGNTKMSIHLIHMRVAAQGFVVGALTLGMGYSMYKEFWAKPKP", "length": 93, "header": "tr|A0A8C2MTT5-1|A0A8C2MTT5_CRIGR Isoform 1 of HIG1 domain family member 1A, mitochondrial OS=Cricetulus griseus OX=10029 GN=Higd1a PE=4 SV=1 CANONICAL=A0A8C2MTT5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"Prkag2", "type": "synonym", "evidence": [ { "id": "XP_007640149", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640149" } ] } ], "protein_names": [ { "name": "5'-AMP-activated protein kinase subunit gamma-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007640149", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640149" } ] }, { "name": "5'-AMP-activated protein kinase subunit gamma-2 isoform X4", "type": "synonym", "evidence": [ { "id": "A0A8C2MTX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTX8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 70 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613842.1) and transcript sequence (IACG01049601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007640149", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640149" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTX8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTX8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Prkag2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTX8", "locus": {} } ], "crossref": [ { "id": "cd04618", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04618", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04641", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04641", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758649", "url": "https://www.ncbi.nlm.nih.gov/gene/100758649", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050511", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050511", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758649", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758649", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MTX8", "url": "https://www.orthodb.org/?gene=A0A8C2MTX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MW92", "url": "https://www.orthodb.org/?gene=A0A8C2MW92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GEF5", "url": "https://www.orthodb.org/?gene=A0A9J7GEF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13780", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13780", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13780:SF122", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13780:SF122", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007640149", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640149", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MTX8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MTX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MW92", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MW92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GFJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSAAMDTKKKKEVSSPGGSGGKKNPSLKRRSLRVHIPDLSSFAMPLLDGDVESSEKHSSRKVDSPFSSGSPSRGLFSRGPQPRPSSPVSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPSTSPGGIRFFSRSRKTSSVSSSPSTPTQVTKPHPFPLESYKQEPERLENRIYASSSPPDTGQRFCLAFQSPVRPPLASPTHHVPLRNAALAAAPGPAEAGMLEKLEFQEEAEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLETLETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETEAE", "length": 567, "header": "tr|A0A8C2MTX8-1|A0A8C2MTX8_CRIGR Isoform 1 of 5'-AMP-activated protein kinase subunit gamma-2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Prkag2 PE=3 SV=1 CANONICAL=A0A8C2MTX8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MTX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTX8/entry#A0A8C2MTX8-1", "sequence": { "sequence": "MGSAAMDTKKKKEVSSPGGSGGKKNPSLKRRSLRVHIPDLSSFAMPLLDGDVESSEKHSSRKVDSPFSSGSPSRGLFSRGPQPRPSSPVSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPSTSPGGIRFFSRSRKTSSVSSSPSTPTQVTKPHPFPLESYKQEPERLENRIYASSSPPDTGQRFCLAFQSPVRPPLASPTHHVPLRNAALAAAPGPAEAGMLEKLEFQEEAEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLETLETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETEAE", "length": 567, "header": "tr|A0A8C2MTX8-1|A0A8C2MTX8_CRIGR Isoform 1 of 5'-AMP-activated protein kinase subunit gamma-2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Prkag2 PE=3 SV=1 CANONICAL=A0A8C2MTX8-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MW92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTX8/entry#A0A8C2MW92-1", "sequence": { "sequence": "MKRFGSLRGNKKPKDQNGSTQRRQSEPHGLFASSVSSSPSTPTQVTKPHPFPLESYKQEPERLENRIYASSSPPDTGQRFCLAFQSPVRPPLASPTHHVPLRNAALAAAPGPAEAGMLEKLEFQEEAEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLETLETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETEAE", "length": 443, "header": "tr|A0A8C2MW92-1|A0A8C2MW92_CRIGR Computationally mapped isoform of 5'-AMP-activated protein kinase subunit gamma-2 isoform X6 OS=Cricetulus griseus OX=10029 GN=Prkag2 PE=3 SV=1 CANONICAL=A0A8C2MTX8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GEF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTX8/entry#A0A9J7GEF5-1", "sequence": { "sequence": "MVSASSVSSSPSTPTQVTKPHPFPLESYKQEPERLENRIYASSSPPDTGQRFCLAFQSPVRPPLASPTHHVPLRNAALAAAPGPAEAGMLEKLEFQEEAEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLETLETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETEAE", "length": 415, "header": "tr|A0A9J7GEF5-1|A0A8C2MTX8_CRIGR Computationally mapped isoform of 5'-AMP-activated protein kinase subunit gamma-2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Prkag2 PE=3 SV=1 CANONICAL=A0A8C2MTX8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GFJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTX8/entry#A0A9J7GFJ1-1", "sequence": { "sequence": "MGSAAMDTKKKKEVSSPGGSGGKKNPSLKRRSLRVHIPDLSSFAMPLLDGDVESSEKHSSRKVDSPFSSGSPSRGLFSRGPQPRPSSPVSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPSTSPGGIRFFSRSRKTEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLETLETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETEAE", "length": 472, "header": "tr|A0A9J7GFJ1-1|A0A9J7GFJ1_CRIGR Computationally mapped isoform of 5'-AMP-activated protein kinase subunit gamma-2 isoform X5 OS=Cricetulus griseus OX=10029 GN=Prkag2 PE=3 SV=1 CANONICAL=A0A8C2MTX8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEF5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613640.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497092", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497092" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MU43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tcf23", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43", "locus": {} } ], "crossref": [ { "id": "100764736", "url": "https://www.ncbi.nlm.nih.gov/gene/100764736", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764736", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764736", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RTRQDLW", "url": "https://omabrowser.org/oma/group/RTRQDLW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MU43", "url": "https://www.orthodb.org/?gene=A0A8C2MU43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23349", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23349", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23349:SF58", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23349:SF58", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003497092", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497092", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MU43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MU43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQQATGVPVMPRAGHGQTKAKALLGTDRKRIRLSRTRQDLWDDTSWSNHRSSRATSAPRGTRAKGTAHGRSEASPENAARERTRVRTLRQAFLALQAALPAVPPDTKLSKLDVLVLATSYIAHLTRTLGHELPGPAWPPFLRGLRYLHPLKKWPMRSRLYAGGLGCSSLDSTPATAASQRTRDEEVGAQVSVATDILLLSDPVSPSPGNK", "length": 211, "header": "tr|A0A8C2MU43-1|A0A8C2MU43_CRIGR Isoform 1 of Transcription factor 23 OS=Cricetulus griseus OX=10029 GN=Tcf23 PE=4 SV=1 CANONICAL=A0A8C2MU43-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MU43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43/entry#A0A8C2MU43-1", "sequence": { "sequence": "MSQQATGVPVMPRAGHGQTKAKALLGTDRKRIRLSRTRQDLWDDTSWSNHRSSRATSAPRGTRAKGTAHGRSEASPENAARERTRVRTLRQAFLALQAALPAVPPDTKLSKLDVLVLATSYIAHLTRTLGHELPGPAWPPFLRGLRYLHPLKKWPMRSRLYAGGLGCSSLDSTPATAASQRTRDEEVGAQVSVATDILLLSDPVSPSPGNK", "length": 211, "header": "tr|A0A8C2MU43-1|A0A8C2MU43_CRIGR Isoform 1 of Transcription factor 23 OS=Cricetulus griseus OX=10029 GN=Tcf23 PE=4 SV=1 CANONICAL=A0A8C2MU43-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MU43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MU43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764736", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764736", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TAK9-1", "protein_name": "Transcription factor 23", "gene_name": "TCF23", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQREARGARAMPGLGQSPAKATPRLLAGTERKRSRLSRRGQDLWEESSWSNQRWSRTAPNPRGARARSLARGRSEASPENAARERSRVRTLRQAFLALQATLPAVPPDTKLSKLDVLVLATSYIAHLTRTLGQEMPGPSWPPFLRGLRYLHPLKKWPMRSRLYAGGLGCSGLDSTTASNSGQRTKEAEAGPHVSGEPDALLSTRPLSPAPSDK", "length": 214 }, "evidence": [ { "id": "A0A8C2MU43", "url": "https://omabrowser.org/oma/group/A0A8C2MU43/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SED6-1", "protein_name": "Transcription factor 23", "gene_name": "TCF23", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSQREAGGALAMPGVGQSPAKATPRLLAGTDRKRSRLSRTGQDLWEDTSWSGQRWSGAAPSSRGARARSLARGRSEASPENAARERSRVRTLRQAFLALQATLPAVPPDTKLSKLDVLVLATSYIAHLTRTLGHEMPGPAWPPFLRGLRYLHPLKKWPMRSRLYAGGLGCSGLDSTTAATSGQRTKEAEAGPQGSGEADALLPTRPLSPALGDK", "length": 214 }, "evidence": [ { "id": "A0A8C2MU43", "url": "https://omabrowser.org/oma/group/A0A8C2MU43/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7RTU1-1", "protein_name": "Transcription factor 23", "gene_name": "TCF23", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQRKARGPPAMPGVGHSQTQAKARLLPGADRKRSRLSRTRQDPWEERSWSNQRWSRATPGPRGTRAGGLALGRSEASPENAARERSRVRTLRQAFLALQAALPAVPPDTKLSKLDVLVLAASYIAHLTRTLGHELPGPAWPPFLRGLRYLHPLKKWPMRSRLYAGGLGYSDLDSTTASTPSQRTRDAEVGSQVPGEADALLSTTPLSPALGDK", "length": 214 }, "evidence": [ { "id": "A0A8C2MU43", "url": "https://omabrowser.org/oma/group/A0A8C2MU43/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JLR5-1", "protein_name": "Transcription factor 23", "gene_name": "Tcf23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQEATEAPAMPGEGHGHNKAKARWLLGTDRKRSRINRTRQDLWEDTSWSNHRLSRATSAPRGTRARGTAHGRSEASPENAARERTRVKTLRQAFLALQAALPAVPPDTKLSKLDVLVLATSYIAHLTRTLGHELPGPAWPPFVRGLRYLHPLKKWPMRSRLYAGGLGCSDLDSTTAITTGQRCKDAELGSQDSVAAESLLTSPAFGNK", "length": 209 }, "evidence": [ { "id": "A0A8C2MU43", "url": "https://omabrowser.org/oma/group/A0A8C2MU43/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MU43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43" } ], "pmid": "" }, { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MU43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43" } ], "pmid": "" }, { "name": "negative regulation of muscle cell differentiation", "id": "GO:0051148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051148", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MU43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MU43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MU43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MU43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MU43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43" } ], "pmid": "" }, { "name": "transcription regulator inhibitor activity", "id": "GO:0140416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140416", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MU43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MU43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MU43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU43" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 125, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MU84-1", "uniprot_ac": "A0A8C2MU84", "uniprot_id": "A0A8C2MU84_CRIGR", "mass": { "chemical_mass": 31637.0, "monoisotopic_mass": 31637.0 }, "refseq": { "ac": "XP_027286313", "name": "F-box only protein 27 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286313" }, "gene_names": [ { "name": "LOC100770350", "type": "recommended", "evidence": [ { "id": "A0A8C2MU84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU84" } ] }, { "name": "LOC100770350", "type": "synonym", "evidence": [ { "id": "XP_027286313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286313" } ] } ], "protein_names": [ { "name": "F-box only protein 27 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027286313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286313" }, { "id": "A0A8C2MU84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU84/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027286313.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027286313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286313" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MU84", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU84" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100770350", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU84", "locus": {} } ], "crossref": [ { "id": "100770350", "url": "https://www.ncbi.nlm.nih.gov/gene/100770350", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770350", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770350", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MU84", "url": "https://www.orthodb.org/?gene=A0A8C2MU84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12125", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12125", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12125:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12125:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04300", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04300", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027286313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286313", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MU84", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MU84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJV3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJV3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSWTSRARVPKPEPDPRETLDLSRLPPELLLVVLSHVPPRSLLLHCRRVCRAWRAMVDGQALWLLVLARDRSAQGRALLSLARRCLPPARPDGPCPLGHFCARRPIGRNLISNPCGQEGLRKWMVQHGGDGWVVEKNKKTVPGAPSQTCFVTSFSWCRKKQVVDLEEKGLWPELLDSGGVEIAVSDWWGARHDSGCKYRLLVKLLDAHQNVLDKFSAVPDPIEQWNNNIYLQVTHVFSNIRRGVRFVSFEHWGQDTQFWAGHYGARVTNSSVTVQVCQS", "length": 280, "header": "tr|A0A8C2MU84-1|A0A8C2MU84_CRIGR Isoform 1 of F-box only protein 27 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100770350 PE=4 SV=1 CANONICAL=A0A8C2MU84-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MU84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU84/entry#A0A8C2MU84-1", "sequence": { "sequence": "MGSWTSRARVPKPEPDPRETLDLSRLPPELLLVVLSHVPPRSLLLHCRRVCRAWRAMVDGQALWLLVLARDRSAQGRALLSLARRCLPPARPDGPCPLGHFCARRPIGRNLISNPCGQEGLRKWMVQHGGDGWVVEKNKKTVPGAPSQTCFVTSFSWCRKKQVVDLEEKGLWPELLDSGGVEIAVSDWWGARHDSGCKYRLLVKLLDAHQNVLDKFSAVPDPIEQWNNNIYLQVTHVFSNIRRGVRFVSFEHWGQDTQFWAGHYGARVTNSSVTVQVCQS", "length": 280, "header": "tr|A0A8C2MU84-1|A0A8C2MU84_CRIGR Isoform 1 of F-box only protein 27 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100770350 PE=4 SV=1 CANONICAL=A0A8C2MU84-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GJV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU84/entry#A0A9J7GJV3-1", "sequence": { "sequence": "MGSWTSRARVPKPEPDPRETLDLSRLPPELLLVVLSHVPPRSLLLHCRRVCRAWRAMVDGQALWLLVLARDRSAQGRALLSLARRCLPPARPDGPCPLGHFCARRPIGRNLISNPCGQEGLRKWMVQHGGDGWVVEKNKKTVPGAPSQTCFVTSFSWCRKKQVVDLEEKGLWPELLDSGGVEIAVSDWWGARHDSGCKYRLLVKLLDAHQNVLDKFSAVPDPIEQWNNNIYLQV", "length": 234, "header": "tr|A0A9J7GJV3-1|A0A9J7GJV3_CRIGR Computationally mapped isoform of F-box only protein 27 isoform X4 OS=Cricetulus griseus OX=10029 GN=LOC100770350 PE=4 SV=1 CANONICAL=A0A8C2MU84-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"url": "https://www.uniprot.org/uniprotkb/A0A8C2MU84" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MU84", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU84" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MU84", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU84" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MU84", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU84" } ], "pmid": "" }, { "name": "glycoprotein catabolic process", "id": "GO:0006516", 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MUA6-1", "uniprot_ac": "A0A8C2MUA6", "uniprot_id": "A0A8C2MUA6_CRIGR", "mass": { "chemical_mass": 40562.0, "monoisotopic_mass": 40562.0 }, "refseq": { "ac": "XP_027263232", "name": "solute carrier family 35 member G1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263232" }, "gene_names": [ { "name": "Slc35g1", "type": "recommended", "evidence": [ { "id": "A0A8C2MUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6" } ] }, { "name": "Slc35g1", "type": "synonym", "evidence": [ { "id": "XP_027263232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263232" } ] } ], "protein_names": [ { "name": "Solute carrier family 35 member G1", "type": "recommended", "evidence": [ { "id": "A0A8C2MUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6/entry#names_and_taxonomy" } ] }, { "name": "Transmembrane protein 20", "type": "synonym", "evidence": [ { "id": "A0A8C2MUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 35 member G1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027263232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263232" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027263232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263232" } ] }, { "annotation": "May play a role in intracellular calcium sensing and homeostasis. May act as a negative regulator of plasma membrane calcium-transporting ATPases preventing calcium efflux from the cell.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUA6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6#function" }, { "database": "UniProtKB", "id": "ARBA00059734", "url": "https://www.uniprot.org/uniprotkb/ARBA00059734#function" }, { "database": "UniProtKB", "id": "A0A9J7GS77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GS77#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUA6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc35g1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6", "locus": {} } ], "crossref": [ { "id": "100756137", "url": "https://www.ncbi.nlm.nih.gov/gene/100756137", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756137", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756137", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MUA6", "url": "https://www.orthodb.org/?gene=A0A8C2MUA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22911", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22911", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22911:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22911:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00892", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00892", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027263232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263232", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MUA6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GS77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GS77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GS77-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GS77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPLEGAAELAADAVELREPELRLEDPASPGEEQADVEAADAPGGGRCWPCGAWVCGGSPGDPEARKKASCPGLGLFYTLLSAFLFSVASLLVKKVQGVHAVEISAFRCMFQMLVIIPCLIYRKSGFIGPKGQRLFLLLRGLFGSCAMILMYYAFQTTSLADATVIAFSCPVFTSIFAWIFLKEKYSLWDALFMLFALVGVILIVRPPFLFGSDTSGMNKSYSEHIKGTFAAIGHAVLAAMTLVILRKMGKSVDYFLSIWYYVILGLPECAVILFIIGGWSIPYCGLDRLFLILIGLLGLGGQIFITKAVQIEKAGLVAIMKTMDIVFAFIFQIAFFDNMPTWWTVGGALCVVASTTGATIRRWIQSSTVQQ", "length": 372, "header": "tr|A0A8C2MUA6-1|A0A8C2MUA6_CRIGR Isoform 1 of Solute carrier family 35 member G1 OS=Cricetulus griseus OX=10029 GN=Slc35g1 PE=3 SV=1 CANONICAL=A0A8C2MUA6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MUA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6/entry#A0A8C2MUA6-1", "sequence": { "sequence": "MEPLEGAAELAADAVELREPELRLEDPASPGEEQADVEAADAPGGGRCWPCGAWVCGGSPGDPEARKKASCPGLGLFYTLLSAFLFSVASLLVKKVQGVHAVEISAFRCMFQMLVIIPCLIYRKSGFIGPKGQRLFLLLRGLFGSCAMILMYYAFQTTSLADATVIAFSCPVFTSIFAWIFLKEKYSLWDALFMLFALVGVILIVRPPFLFGSDTSGMNKSYSEHIKGTFAAIGHAVLAAMTLVILRKMGKSVDYFLSIWYYVILGLPECAVILFIIGGWSIPYCGLDRLFLILIGLLGLGGQIFITKAVQIEKAGLVAIMKTMDIVFAFIFQIAFFDNMPTWWTVGGALCVVASTTGATIRRWIQSSTVQQ", "length": 372, "header": "tr|A0A8C2MUA6-1|A0A8C2MUA6_CRIGR Isoform 1 of Solute carrier family 35 member G1 OS=Cricetulus griseus OX=10029 GN=Slc35g1 PE=3 SV=1 CANONICAL=A0A8C2MUA6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GS77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6/entry#A0A9J7GS77-1", "sequence": { "sequence": "MEPLEGAAELAADAVELREPELRLEDPASPGEEQADVEAADAPGGGRCWPCGAWVCGGSPGDPARKKASCPGLGLFYTLLSAFLFSVASLLVKKVQGVHAVEISAFRCMFQMLVIIPCLIYRKSGFIGPKGQRLFLLLRGLFGSCAMILMYYAFQTTSLADATVIAFSCPVFTSIFAWIFLKEKYSLWDALFMLFALVGVILIVRPPFLFGSDTSGMNKSYSEHIKGTFAAIGHAVLAAMTLVILRKMGKSVDYFLSIWYYVILGLPECAVILFIIGGWSIPYCGLDRLFLILIGLLGLGGQIFITKAVQIEKAGLVAIMKTMDIVFAFIFQIAFFDNMPTWWTVGGALCVVASTTGATIRRWIQSSTVQQ", "length": 371, "header": "tr|A0A9J7GS77-1|A0A9J7GS77_CRIGR Computationally mapped isoform of Solute carrier family 35 member G1 OS=Cricetulus griseus OX=10029 GN=Slc35g1 PE=3 SV=1 CANONICAL=A0A8C2MUA6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUA6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUA6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756137", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756137", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUA6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUA6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of cytosolic calcium ion concentration", "id": "GO:0051480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051480", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUA6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6" } ], "pmid": "" }, { "name": "calcium ion export across plasma membrane", "id": "GO:1990034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990034", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUA6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUA6" }, { "id": "PF00892", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00892" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EamA", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 205, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 219, "end_pos": 221 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"A0A8C2MUB2_CRIGR", "mass": { "chemical_mass": 116967.0, "monoisotopic_mass": 116967.0 }, "refseq": { "ac": "XP_027267025", "name": "SAFB-like transcription modulator isoform X7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267025" }, "gene_names": [ { "name": "Sltm", "type": "recommended", "evidence": [ { "id": "A0A8C2MUB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2" } ] }, { "name": "Sltm", "type": "synonym", "evidence": [ { "id": "XP_027267025", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267025" } ] } ], "protein_names": [ { "name": "SAFB-like transcription modulator", "type": "recommended", "evidence": [ { "id": "A0A8C2MUB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2/entry#names_and_taxonomy" } ] }, { "name": "Modulator of estrogen-induced transcription", "type": "synonym", "evidence": [ { "id": "A0A8C2MUB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2/entry#names_and_taxonomy" } ] }, { "name": "SAFB-like transcription modulator isoform X7", "type": "synonym", "evidence": [ { "id": "XP_027267025", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267025" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267025", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267025" } ] }, { "annotation": "When overexpressed, acts as a general inhibitor of transcription that eventually leads to apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRN4#function" }, { "database": "UniProtKB", "id": "ARBA00056159", "url": "https://www.uniprot.org/uniprotkb/ARBA00056159#function" }, { "database": "UniProtKB", "id": "A0A9J7FU40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU40#function" }, { "database": "UniProtKB", "id": "A0A9J7FW28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW28#function" }, { "database": "UniProtKB", "id": "A0A9J7JNE5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNE5#function" }, { "database": "UniProtKB", "id": "A0A8C2MUB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sltm", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2", "locus": {} } ], "crossref": [ { "id": "cd12678", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12678", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757547", "url": "https://www.ncbi.nlm.nih.gov/gene/100757547", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757547", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757547", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MUB2", "url": "https://www.orthodb.org/?gene=A0A8C2MUB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15683", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15683", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15683:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15683:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027267025", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267025", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MUB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FU40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FU40-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FW28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FW28-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNE5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNE5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAGAVAASAASGQTEGKKITELRVIDLRSELKRRNLDINGVKTVLVSRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKQEADELSGDASVEDDAFVKDCELENQETHEQDGNDELKDLEEFGENEEDIVQSQELLSAEENKKTHELIETEAIEDREKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEANATGKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKETKDYEMNPNHKDGKKEDSVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGCTGSAGGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSAGDKKNTSDRSAKTQASIKKEEKRSSEKLEKKESKDTKKLEKDEKNDNGSSGQTSESMKKSEDKKRISSKSPGHMVILNQTKGDHCRPSRRGRYEKVHGRSKEKERASIDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAVELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDADARFGHGSDYRQQSRFLDFSHRERGRFPDTASVQSSSFESRRERFVGQSEGKKPRPAARREEPSFERYPKNFSDSRRNEPPPPRNELRETDRREVRGERDERRTVILHDRAEVAHPRHPREAGPNPSRPTSWKSEGSMSTDKRESRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVISDRGSGAQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPGYHDTRRIGDGRSGAGMITQHSSTASPVNRIVQMSGNSMPRGSSSGFKPFKSGPPRRF", "length": 1033, "header": "tr|A0A8C2MUB2-1|A0A8C2MUB2_CRIGR Isoform 1 of SAFB-like transcription modulator OS=Cricetulus griseus OX=10029 GN=Sltm PE=4 SV=1 CANONICAL=A0A8C2MUB2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MUB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2/entry#A0A8C2MUB2-1", "sequence": { "sequence": "MAAAAGAVAASAASGQTEGKKITELRVIDLRSELKRRNLDINGVKTVLVSRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKQEADELSGDASVEDDAFVKDCELENQETHEQDGNDELKDLEEFGENEEDIVQSQELLSAEENKKTHELIETEAIEDREKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEANATGKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKETKDYEMNPNHKDGKKEDSVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGCTGSAGGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSAGDKKNTSDRSAKTQASIKKEEKRSSEKLEKKESKDTKKLEKDEKNDNGSSGQTSESMKKSEDKKRISSKSPGHMVILNQTKGDHCRPSRRGRYEKVHGRSKEKERASIDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAVELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDADARFGHGSDYRQQSRFLDFSHRERGRFPDTASVQSSSFESRRERFVGQSEGKKPRPAARREEPSFERYPKNFSDSRRNEPPPPRNELRETDRREVRGERDERRTVILHDRAEVAHPRHPREAGPNPSRPTSWKSEGSMSTDKRESRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVISDRGSGAQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPGYHDTRRIGDGRSGAGMITQHSSTASPVNRIVQMSGNSMPRGSSSGFKPFKSGPPRRF", "length": 1033, "header": "tr|A0A8C2MUB2-1|A0A8C2MUB2_CRIGR Isoform 1 of SAFB-like transcription modulator OS=Cricetulus griseus OX=10029 GN=Sltm PE=4 SV=1 CANONICAL=A0A8C2MUB2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FRN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2/entry#A0A9J7FRN4-1", "sequence": { "sequence": "MAAAAGAVAASAASGQTEGKKITELRVIDLRSELKRRNLDINGVKTVLVSRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKQEADELSGDASVEDDAFVKDCELENQETHEQDGNDELKDLEEFGENEEDIVQSQELLSAEENKKTHELIETEAIEDREKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKEGSLAEADHTAHEEMEANATGKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKETKDYEMNPNHKDGKKEDSVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGCTGSAGGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSAGDKKNTSDRSAKTQASIKKEEKRSSEKLEKKESKDTKKLEKDEKNDNGSSGQTSESMKKSEDKKRISSKSPGHMVILNQTKGDHCRPSRRGRYEKVHGRSKEKERASIDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAVELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDADARFGHGSDYRQQSRFLDFSHRERGRFPDTASVQSSSFERRERFVGQSEGKKPRPAARREEPSFERYPKNFSDSRRNEPPPPRNELRETDRREVRGERDERRTVILHDRAEVAHPRHPREAGPNPSRPTSWKSEGSMSTDKRESRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVISDRGSGAQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPGYHDTRRIGDGRSGAGMITQHSSTASPVNRIVQMSGNSMPRGSSSGFKPFKSGPPRRF", "length": 1014, "header": "tr|A0A9J7FRN4-1|A0A8C2MUB2_CRIGR Computationally mapped isoform of SAFB-like transcription modulator OS=Cricetulus griseus OX=10029 GN=Sltm PE=4 SV=1 CANONICAL=A0A8C2MUB2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FU40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2/entry#A0A9J7FU40-1", "sequence": { "sequence": 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"length": 1032, "header": "tr|A0A9J7FU40-1|A0A8C2MUB2_CRIGR Computationally mapped isoform of SAFB-like transcription modulator OS=Cricetulus griseus OX=10029 GN=Sltm PE=4 SV=1 CANONICAL=A0A8C2MUB2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FW28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2/entry#A0A9J7FW28-1", "sequence": { "sequence": "MAAAAGAVAASAASGQTEGKKITELRVIDLRSELKRRNLDINGVKTVLVSRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKQEADELSGDASVEDDAFVKDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEANATGKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKETKDYEMNPNHKDGKKEDSVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGCTGSAGGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSAGDKKNTSDRSAKTQASIKKEEKRSSEKLEKKESKDTKKLEKDEKNDNGSSGQTSESMKKSEDKKRISSKSPGHMVILNQTKGDHCRPSRRGRYEKVHGRSKEKERASIDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAVELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDADARFGHGSDYRQQSRFLDFSHRERGRFPDTASVQSSSFESRRERFVGQSEGKKPRPAARREEPSFERYPKNFSDSRRNEPPPPRNELRETDRREVRGERDERRTVILHDRAEVAHPRHPREAGPNPSRPTSWKSEGSMSTDKRESRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVISDRGSGAQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPGYHDTRRIGDGRSGAGMITQHSSTASPVNRIVQMSGNSMPRGSSSGFKPFKSGPPRRF", "length": 951, "header": "tr|A0A9J7FW28-1|A0A8C2MUB2_CRIGR Computationally mapped isoform of SAFB-like transcription modulator OS=Cricetulus griseus OX=10029 GN=Sltm PE=4 SV=1 CANONICAL=A0A8C2MUB2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JNE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2/entry#A0A9J7JNE5-1", "sequence": { "sequence": "MAAAAGAVAASAASGQTEGKKITELRVIDLRSELKRRNLDINGVKTVLVSRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKQEADELSGDASVEDDAFVKDGEEEENEKEGSLAEADHTAHEEMEANATGKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKETKDYEMNPNHKDGKKEDSVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGCTGSAGGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSAGDKKNTSDRSAKTQASIKKEEKRSSEKLEKKESKDTKKLEKDEKNDNGSSGQTSESMKKSEDKKRISSKSPGHMVILNQTKGDHCRPSRRGRYEKVHGRSKEKERASIDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAVELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDADARFGHGSDYRQQSRFLDFSHRERGRFPDTASVQSSSFESRRERFVGQSEGKKPRPAARREEPSFERYPKNFSDSRRNEPPPPRNELRETDRREVRGERDERRTVILHDRAEVAHPRHPREAGPNPSRPTSWKSEGSMSTDKRESRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVISDRGSGAQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPGYHDTRRIGDGRSGAGMITQHSSTASPVNRIVQMSGNSMPRGSSSGFKPFKSGPPRRF", "length": 933, "header": "tr|A0A9J7JNE5-1|A0A8C2MUB2_CRIGR Computationally mapped isoform of SAFB-like transcription modulator OS=Cricetulus griseus OX=10029 GN=Sltm PE=4 SV=1 CANONICAL=A0A8C2MUB2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRN4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRN4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757547", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757547", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2" } ], "pmid": "" }, { "name": "regulation of mRNA processing", "id": "GO:0050684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050684", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 487, "end_pos": 489, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" }, { "start_pos": 560, "end_pos": 562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 821, "end_pos": 823, "annotation": "n_glycosylation_sequon" }, { "start_pos": 919, "end_pos": 921, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MUB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 384, "end_pos": 462, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MUB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUB2" }, { "id": "PS50800", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAP", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 56, "start_aa": "Ile", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 232, "end_pos": 234 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 487, "end_pos": 489 }, { "start_pos": 529, "end_pos": 531 }, { "start_pos": 560, "end_pos": 562 }, { "start_pos": 821, "end_pos": 823 }, { "start_pos": 919, "end_pos": 921 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MUF0-1", "uniprot_ac": "A0A8C2MUF0", "uniprot_id": "A0A8C2MUF0_CRIGR", "mass": { "chemical_mass": 32711.0, "monoisotopic_mass": 32711.0 }, "refseq": { "ac": "XP_007653326", "name": "solute carrier family 25 member 34 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653326" }, "gene_names": [ { "name": "Slc25a34", "type": "recommended", "evidence": [ { "id": "A0A8C2MUF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUF0" } ] }, { "name": "Slc25a34", "type": "synonym", "evidence": [ { "id": "XP_007653326", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653326" } ] } ], "protein_names": [ { "name": "Solute carrier family 25 member 34", "type": "recommended", "evidence": [ { "id": "A0A8C2MUF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUF0/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 25 member 34 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007653326", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653326" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617400.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007653326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653326" } ] }, { "annotation": "Putative antiporter that exchanges dicarboxylates and sulfur oxoanions across the inner membrane of mitochondria.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUF0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUF0#function" }, { "database": "UniProtKB", "id": "ARBA00037259", "url": "https://www.uniprot.org/uniprotkb/ARBA00037259#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUF0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUF0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc25a34", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUF0", "locus": {} } ], "crossref": [ { "id": "100771069", "url": "https://www.ncbi.nlm.nih.gov/gene/100771069", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771069", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771069", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KANCEDH", "url": "https://omabrowser.org/oma/group/KANCEDH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MUF0", "url": "https://www.orthodb.org/?gene=A0A8C2MUF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45928", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45928", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45928:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45928:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007653326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653326", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "76595", "url": "https://www.rhea-db.org/rhea/76595", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MUF0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPTMDAEDMVSPAVDLVLGASACCLACVFTNPLEVVKTRLQLQGELQAPGTYPRPYRGFVSSVAAVARADGLWGLQKGLAAGLLYQGLMNSVRFYCYSLACQAGLTQQPGGTVVAGAVAGALGAFVGSPAYLVKTQLQAQTVAALAVGHQHQHQSVLGALETIWRQQGLLGLWRGVGGAVPRVTVGSAAQLATFASAKAWVQERQWFLEDSWLVTLTGGMISSIAVAAVMTPFDVVSTRLYNQPVDRAGRGQLYGGLADCLVKICQQEGPLALYKGLGLAYLRLGPHTILSMFFWDELRKLAARAQR", "length": 308, "header": "tr|A0A8C2MUF0-1|A0A8C2MUF0_CRIGR Isoform 1 of Solute carrier family 25 member 34 OS=Cricetulus griseus OX=10029 GN=Slc25a34 PE=3 SV=1 CANONICAL=A0A8C2MUF0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MUF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUF0/entry#A0A8C2MUF0-1", "sequence": { "sequence": "MAPTMDAEDMVSPAVDLVLGASACCLACVFTNPLEVVKTRLQLQGELQAPGTYPRPYRGFVSSVAAVARADGLWGLQKGLAAGLLYQGLMNSVRFYCYSLACQAGLTQQPGGTVVAGAVAGALGAFVGSPAYLVKTQLQAQTVAALAVGHQHQHQSVLGALETIWRQQGLLGLWRGVGGAVPRVTVGSAAQLATFASAKAWVQERQWFLEDSWLVTLTGGMISSIAVAAVMTPFDVVSTRLYNQPVDRAGRGQLYGGLADCLVKICQQEGPLALYKGLGLAYLRLGPHTILSMFFWDELRKLAARAQR", "length": 308, "header": "tr|A0A8C2MUF0-1|A0A8C2MUF0_CRIGR Isoform 1 of Solute carrier family 25 member 34 OS=Cricetulus griseus OX=10029 GN=Slc25a34 PE=3 SV=1 CANONICAL=A0A8C2MUF0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 185, "start_aa": "Thr", "end_pos": 185, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr185", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUF0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUF0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUF0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUF0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771069", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771069", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NWQ1-1", "protein_name": "Solute carrier family 25 member 34", "gene_name": "SLC25A34", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAGTGALGPFPAAALHDFPYPSQTAAPVSHGPPAGGVPPAADLVLGAAAGCMACVLTNPLEVVKTRLQLQGELRAPGTYPRPYRGVLRAVGAVCRADGLRGLQKGLAAGLLYQGLMNGVRFYCYSCALDAGWTGWPGGTVVAGAVAGAVGAFVGSPAYLVKTHLQAQTLSAMAVGHQHNHESISDAFGSIYRQHGVAGLWRGVSGAVPRVAVGSAAQLATFASAKDWVCQHQWFGEGSWAAVLAGGMVSGVAVAVTMTPFDVVSTRLYNQPVEADGTGKLYRGFLDCFAQISSKEGLLGLYKGIGAVYLRLGPHTVLSLFFWDELRRMVRPQPPPGP", "length": 338 }, "evidence": [ { "id": "A0A8C2MUF0", "url": "https://omabrowser.org/oma/group/A0A8C2MUF0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2ADF7-1", "protein_name": "Solute carrier family 25 member 34", "gene_name": "Slc25a34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPTQAQMAPAMDSREMVSPAVDLVLGASACCLACVFTNPLEVVKTRLQLQGELQAPGTYPRPYRGFVSSVAAVARADGLWGLQKGLAAGLLYQGLMNGVRFYCYSLACQAGLTQQPGGTVVAGAAAGALGAFVGSPAYLVKTQLQAQTVATMAVGHQHQHQGVLSALETIWRQQGMLGLWRGVGGAVPRVTVGSAAQLATFTSAKAWVQDRQWFLEDSWLVTLAGGMISSIAVVAVMTPLDVVSTRLYNQPVDRAGRGQLYGGLADCLVKTCQQEGPLALYKGLGPAYLRLGPHTILSMFFWDELRKLVARAQHQGT", "length": 318 }, "evidence": [ { "id": "A0A8C2MUF0", "url": "https://omabrowser.org/oma/group/A0A8C2MUF0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3SZK0-1", "protein_name": "Solute carrier family 25 member 34", "gene_name": "SLC25A34", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "METVPPAVDLVLGASACCLACVFTNPLEVVKTRLQLQGELQKRGTYPRLYRGFVASVVAVVRADGLCGLQKGLAAGLLYQGLMNGVRFYCYSLACQAGLSQQPGGTVVAGAVAGALGAFVGSPAYLVKTQLQAQTVAAMAVGHQHHHESLLGALETIWRQQGLAGLWRGVGGAVPRVMVGSAAQLATFASAKAWVQERQWLPEDSWLVALAGGMISSIAVVAVMTPFDVVSTRLYNQPVDGAGRGKLYGGLTDCLVKIWRQEGPLALYKGLGPVYLRLGPHTILSMLFWDELRKLAGWGQHQGS", "length": 304 }, "evidence": [ { "id": "A0A8C2MUF0", "url": "https://omabrowser.org/oma/group/A0A8C2MUF0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PIV7-1", "protein_name": "Solute carrier family 25 member 34", "gene_name": "SLC25A34", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METVPPAVDLVLGASACCLACVFTNPLEVVKTRLQLQGELQARGTYPRPYHGFIASVAAVARADGLWGLQKGLAAGLLYQGLMNGVRFYCYSLACQAGLTQQPGGTVVAGAVAGALGAFVGSPAYLIKTQLQAQTVAAVAVGHQHNHQTVLGALETIWRQQGLLGLWQGVGGAVPRVMVGSAAQLATFASAKAWVQKQQWLPEDSWLVALAGGMISSIAVVVVMTPFDVVSTRLYNQPVDTAGRGQLYGGLTDCMVKIWRQEGPLALYKGLGPAYLRLGPHTILSMLFWDELRKLAGRAQHKGT", "length": 304 }, "evidence": [ { "id": "A0A8C2MUF0", "url": "https://omabrowser.org/oma/group/A0A8C2MUF0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUF0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUF0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "76595", "name": "", "equation": "a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "76595", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/76595" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 185 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MUG2-1", "uniprot_ac": "A0A8C2MUG2", "uniprot_id": "A0A8C2MUG2_CRIGR", "mass": { "chemical_mass": 120106.0, "monoisotopic_mass": 120106.0 }, "refseq": { "ac": "XP_007644305", "name": "protein FAM214A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644305" }, "gene_names": [ { "name": "Fam214a", "type": "recommended", "evidence": [ { "id": "A0A8C2MUG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUG2" } ] }, { "name": "Fam214a", "type": "synonym", "evidence": [ { "id": "XP_007644305", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644305" } ] } ], "protein_names": [ { "name": "Atos homolog protein A", "type": "recommended", "evidence": [ { "id": "A0A8C2MUG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUG2/entry#names_and_taxonomy" } ] }, { "name": "protein FAM214A", "type": "synonym", "evidence": [ { "id": "XP_007644305", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644305" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 129 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613582.1) and transcript sequence (IACG01058873.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007644305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644305" } ] }, { "annotation": "Transcription regulator that syncronizes transcriptional and translational programs to promote macrophage invasion of tissues.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUG2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUG2#function" }, { "database": "UniProtKB", "id": "ARBA00037191", "url": "https://www.uniprot.org/uniprotkb/ARBA00037191#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUG2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUG2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fam214a", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUG2", "locus": {} } ], "crossref": [ { "id": "100753759", "url": "https://www.ncbi.nlm.nih.gov/gene/100753759", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753759", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753759", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QTHPRSQ", "url": "https://omabrowser.org/oma/group/QTHPRSQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MUG2", "url": "https://www.orthodb.org/?gene=A0A8C2MUG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13199", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13199", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13199:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13199:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13889", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13889", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13915", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13915", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007644305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644305", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MUG2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPDRDALDEYFEYDAEEFLVSLALLITEGRTPECSVKGRAESFHCPPAQSRFPGTARHECSDKLAQCRQARRTRSEVTLLWKNNLPIMVEVMLLPDCCYSDEGPSTEGTDLNDPAIKQDALLLERWILEPVPRQNGDRFIEEKALLLAVRSFVFFSQLSAWLSVSHGAIPRNILYRISAADVDLQWTFSQTPTEHVFPVPNVSHNVALKVSVQSLPRQAHYPVLTCSIHTNILYEKRIQEQELKAYQHRGPGEIEHRCPSSSQSLCNKHTWTMAPVSALHVRSGMTPEFTAAIRNVRLCPGTGSKSDHGASQASVLGFSGTMGEVRSQEASVRTLKSLSVIDSSVSSCQSSRQAVGEPNPLMDSLIQDRQEVIARIAQHLIHCDPSSSRMSEHPFSTQESTSLGSKLHRVPQEIEGVRRCKEAFSVSFGSPEIRSSDDTSEGKGRGKSETTQGETCTSHSPYPRQPVGETNPLIGSLLQERQDVIARIAQHLEHIDPTAHIPRPAFSKHDSNSIPSKVFRSSYDDKTLLKVNRDNASLSAAHTEVSLLGDRGDGKSPQPSKCFRSFKYSPQEKSLKHEVRTQHQEHPDDIIHSTGQDAHKAAGLLTSSNMTLCNESNLDLISRLESTPCKSQHKEQEMSREIEKQCSHCNSIDKQFCTNKCTEKIKDENYNPGSPSQLQCDDSKGIDSKLKVTVSEMSDCFNKYKTNCSIKDSKRSKTCEQSSQLSTENDLSEDTEGFRCTASNQLKTEQEEKEDSAAGKPQRKSVKHCLSTSERLKSADVLRDTLKHSSVWRKHNFHSLDGTSTRAFHPQTGLPLLSSPVPQRKTQSGCFDLDTSLLHLRSLSSRSSRPCLNIEEDPDAHEKPFLSSSAPPITSLSLLGNFEESVLNYRLDPLGIVDGFTAEVGASGTFCPTHLTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVMYDLRGMPANHQTFLRQRTFSVPVKQEMKRSINKENVQHTAQLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1076, "header": "tr|A0A8C2MUG2-1|A0A8C2MUG2_CRIGR Isoform 1 of Atos homolog protein A OS=Cricetulus griseus OX=10029 GN=Fam214a PE=3 SV=1 CANONICAL=A0A8C2MUG2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MUG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUG2/entry#A0A8C2MUG2-1", "sequence": { "sequence": "MKPDRDALDEYFEYDAEEFLVSLALLITEGRTPECSVKGRAESFHCPPAQSRFPGTARHECSDKLAQCRQARRTRSEVTLLWKNNLPIMVEVMLLPDCCYSDEGPSTEGTDLNDPAIKQDALLLERWILEPVPRQNGDRFIEEKALLLAVRSFVFFSQLSAWLSVSHGAIPRNILYRISAADVDLQWTFSQTPTEHVFPVPNVSHNVALKVSVQSLPRQAHYPVLTCSIHTNILYEKRIQEQELKAYQHRGPGEIEHRCPSSSQSLCNKHTWTMAPVSALHVRSGMTPEFTAAIRNVRLCPGTGSKSDHGASQASVLGFSGTMGEVRSQEASVRTLKSLSVIDSSVSSCQSSRQAVGEPNPLMDSLIQDRQEVIARIAQHLIHCDPSSSRMSEHPFSTQESTSLGSKLHRVPQEIEGVRRCKEAFSVSFGSPEIRSSDDTSEGKGRGKSETTQGETCTSHSPYPRQPVGETNPLIGSLLQERQDVIARIAQHLEHIDPTAHIPRPAFSKHDSNSIPSKVFRSSYDDKTLLKVNRDNASLSAAHTEVSLLGDRGDGKSPQPSKCFRSFKYSPQEKSLKHEVRTQHQEHPDDIIHSTGQDAHKAAGLLTSSNMTLCNESNLDLISRLESTPCKSQHKEQEMSREIEKQCSHCNSIDKQFCTNKCTEKIKDENYNPGSPSQLQCDDSKGIDSKLKVTVSEMSDCFNKYKTNCSIKDSKRSKTCEQSSQLSTENDLSEDTEGFRCTASNQLKTEQEEKEDSAAGKPQRKSVKHCLSTSERLKSADVLRDTLKHSSVWRKHNFHSLDGTSTRAFHPQTGLPLLSSPVPQRKTQSGCFDLDTSLLHLRSLSSRSSRPCLNIEEDPDAHEKPFLSSSAPPITSLSLLGNFEESVLNYRLDPLGIVDGFTAEVGASGTFCPTHLTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVMYDLRGMPANHQTFLRQRTFSVPVKQEMKRSINKENVQHTAQLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1076, "header": "tr|A0A8C2MUG2-1|A0A8C2MUG2_CRIGR Isoform 1 of Atos homolog protein A OS=Cricetulus griseus OX=10029 GN=Fam214a PE=3 SV=1 CANONICAL=A0A8C2MUG2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUG2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUG2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUG2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUG2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753759", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753759", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZMC3-1", "protein_name": "Atos homolog protein A", "gene_name": "Atosa", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVFSGNKGLRRQDALDEYFEYDAEEFLVSLALLITEGRTPECSVKGRAESFHCPPAQSRFPGAARHECSDKLAQCRQARRTRSEVTLLWKNNLPIMVEVMLLPDCCYSDEGPSTEGTDLNDPAIKQDALLLERWILEPVPRQNGDRFIEEKALLLAVRSFVFFSQLSAWLSVSHGAIPRNILYRISAADVDLQWSFSQTPTEHVFPVPNVSHNVALKVSVQSLPRQAHYPVLTCSIHTNIGLYEKRIQEQELRACQHRGPGEVEYRCPSSSQSLCSKHTWTMAPVSALHVRSGMPPEYTAAIRNVRLCPGTGSKSDNGTPQASVLGFSGTGEVRSQEASVRTFKSLSVIDSSVSSCQSSRQPVGEPNPLIDSLIQDRQEVIARIAQHLIHCDPSSSRMSELPFNTPESTSLSPKLHPVSQESGYSRRCKEAFSVSFGSPEFGSPGDSKEGKVKEKLETRQGETCASHSPYPRQPAGEANPLIGSLLLERQDVIARIAQHLEHIDPTAHIPRPAFSKHDSNSIPSKVFRSSFHDKTMLKKDRENVSVSATHTEVSLLGDRGDGKSPKPSKCFRSFKNSPQEKSLKPEESAQHQNHPDDITHTARQELLNKAAGLLTSSNSSLCNESSLALIGRLESTSCKLQLRKQEMSHETEKQCLHCNSIDKQICTNKCTEKIKDENSPGSLSHLQCDESRGIDPKIKVTMLEMPDYLNKYKTNCSNKDSKRSKTCEQNIQLGTENYLSEDTEGSKSTISDQLKTEQEENKDSVAGKPPSVKHCLSTSERLKNADMLDFSSQRTTLKHSSVWRKHDFHSLDGTSTRAFHPQTGLPLLSSPVPQRKTQSGCFDLDTSLLHLRSLSSKSSRPCLNIEADPGVHEKPFLSSSAPPITSLSLLGNFEESVLNYRLDPLGIVDGFTAEVGASGTFCPTHLTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVVYDLRSMPANHQTFLRQRTFSVPVKQEMKRSINKENVQHTAQLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1086 }, "evidence": [ { "id": "A0A8C2MUG2", "url": "https://omabrowser.org/oma/group/A0A8C2MUG2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q32MH5-1", "protein_name": "Atos homolog protein A", "gene_name": "ATOSA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPDRDTLDEYFEYDAEEFLVSLALLITEGRTPECSVKGRTESFHCPPAQSCYPVTTKHECSDKLAQCRQARRTRSEVTLLWKNNLPIMVEMMLLPDCCYSDDGPTTEGIDLNDPAIKQDALLLERWILEPVPRQNGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGAIPRNILYRISAADVDLQWNFSQTPIEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNIGLYEKRIQQHKLKTHQHHNPNEAEQCGTNSSQRLCSKQTWTMAPESVLHAKSGPSPEYTAAVKNIKLYPGTGSKSDHGTSQANILGFSGIGDIKSQETSVRTLKSFSMVDSSISNRQSFWQSAGETNPLIGSLIQERQEIIARIAQHLIHCDPSTSHVSGRPFNTQESSSLHSKLFRVSQENENVGKGKEAFSMTFGSPEFSSPEDTNEGKIRLKPETPRSETCISNDFYSHMPVGETNPLIGSLLQERQDVIARIAQHLEHIDPTASHIPRQSFNMHDSSSVASKVFRSSYEDKNLLKKNKDESSVSISHTKCSLLGDISDGKNLVPNKCFTSFKNNSKEKCSLKHQTRNQCQNNPSEIIQSTYQETQNKSSSLSTSSILSQHKENNLDLTSRFKEQEMSNGIDKQYSNCTTIDKQICTNKYKEKIINENYNPKFFGNLQSDDSKKNDSKIKVTVLEMSEYLNKYESMSSNKDSKRPKTCEQNTQLNSIENYLNKDNEGFKCKKSDQLKNEQDKQEDPTNEKSQNYSQRRSIKDCLSTCEQPKNTEVLRTTLKHSNVWRKHNFHSLDGTSTRAFHPQTGLPLLSSPVPQRKTQSGCFDLDSSLLHLKSFSSRSPRPCLNIEDDPDIHEKPFLSSSAPPITSLSLLGNFEESVLNYRFDPLGIVDGFTAEVGASGAFCPTHLTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVIYDLRDMPANHQTFLRQRTFSVPVKQEVKRSVNKENIRHTEERLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1076 }, "evidence": [ { "id": "A0A8C2MUG2", "url": "https://omabrowser.org/oma/group/A0A8C2MUG2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5ZI58-1", "protein_name": "Atos homolog protein A", "gene_name": "ATOSA", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNAERNGSSTDTLDEYFEYEAEEFLVSLALLITEGRTPEHSIKGRTEGFHCPPAQSSQPPTTKHECSDKLAQCRQARRTRSEVMLLWKNNIPIMVEVMLLPDCCYSDEGPNTEGNDLNDPAIKQDALLLERWILEPVPRQSGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGAVPRNILYRVSAADVDLQWTFSQTPTEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNLSYYEKQMKERKLHQHSESSTAELCGTSSPQRVCGKQAWTVIPEGLLNVKKTPEFTSSIRNLKLYPSTGLGSDFAASQSKIQCYNAAADSKTQSHETAVRTFKSLSLVDSRVSNGHCSHQSTGETNPLIGSLLQERQEVIARIAQHLIHCDPATSPVVAGRPFNMRETSTPTPKAYRSTYEDESLLRKGKETSPVPTVNLDNAIQEDGGEGKTRAIPEMPRLNPRAPVNHCGRPSAGEGNPLIDSLLQERRDVIARIAQHLIHCDPATSHVNGRPFKIHETSPVSSKIFRSTYEDENLLKKVKQPSSVSFAKSSFSLLEDSSKSKLKTPDTPISPRLDGESKASLKLQARRKLVLAKPSDAVQNAFHQTSNKTSHSFTNTHTSSSCVKENKSELLDKLEMMQSDYVQKDQITNRIKQCSNFSSVDEQICTNKLKERTVVSESNNTGTLNNLQIDKCRILEGTKKATVMQASDSLHKNELKCSDKDSKKPSIYEQNTQLISIENYLNKDHDNFKNKNRQDKTKAAHDENEEPVGLDFQSTSQKKPTEDGSMRCERLKNPDVQRAPSLKHTNTWRKHNFRSLDGTSTKAFHPRTGLPLLSSPVPQRKTHSGCFDLDSSLLQLKCLSARSPQQCINRESDPESHGKPFLSSSAPPVTSLSLLGNFEESVLNFRLDPLGIVEGFTAEVGASGVFCPTHMTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVIYDLREMPANHQTFLRQRTFSVPVRREIKRTVNKENSQQTEERLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1093 }, "evidence": [ { "id": "A0A8C2MUG2", "url": "https://omabrowser.org/oma/group/A0A8C2MUG2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q69ZK7-1", "protein_name": "Atos homolog protein A", "gene_name": "Atosa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPDRDALDEYFEYDAEEFLVSLALLITEGRTPECSVKGRAESFHCPPAQSRFPGTARHECSDKLAQCRQARRTRSEVTLLWKNNLPIMVEVMLLPDCCYSDEGPSTEGADLNDPAIKQDALLLERWILEPVPRQNGDRFIEEKALLLAVRSFVFFSQLSAWLSVSHGAIPRNILYRISAADVDLQWSFSQTPTEHVFPVPNVSHNVALKVSVQSLPRQAHYPVLTCSIHTNIGLYEKRIQEQELRACQHHGPGEVEYRCPSSSQSLCSKHTWTMAPVSALHVRSGMPPEYTAAIRNVRLCPGTGSKSDQGAPQASVLGFSGTGGEVRSQEASVRTFKSLPVVDSSVSSCQSSRQPVGEPNPLMDSLIQDRQEVIARIAQHLIHCDPSSSRMSELPFNTQESTSLSPKLHPVSQESGCVRRYKEAFSVSFGSPEFGSPGDSREGKVREKSETRPGETCTSHSLYPRQPAGEANPLIGSLLQERQDVIARIAQHLEHIDPAAHIPRPAFSKHDSNSIPSKVFRSSFDDKTLLKKGRENVSVSVSHTEVSLLGDRGDGESLKPSKCLRSFKYSPQEKPLKPEVRTQHQNHPDSITPTARQELLNKAAGLLTSSNTALCKESSLGLVSRLESTSCKLQLKEQEMSHETEKQCLHCNSIDKQICTNTCTEKINDEHSPGSLRHLQCDDSKGIDSKLKVTLLEMPDSLNKNKTNCSSKDSKRSKTCEQSIRVGTENDLSEENEGPGSTVSDRLKTEQEAKRDSGAGKPHSVKHCLSAGERLHSADMLRTTLKHSSVWRKHNFHSLDGTSTRAFHPQTGLPLLSSPVPQRKTQSGCFDLDASLLHLRSLSSKSSRPCLNIDEDPDVHEKPFLSSSAPPITSLSLLGNFEESVLNYRLDPLGIVDGFTAEVGASGTFCPTHLTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVVYDLRGMPANHQTFLRQRTFSVPVKQEMKRSINKENVQHTAQLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1075 }, "evidence": [ { "id": "A0A8C2MUG2", "url": "https://omabrowser.org/oma/group/A0A8C2MUG2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUG2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" }, { "start_pos": 615, "end_pos": 617, "annotation": "n_glycosylation_sequon" }, { "start_pos": 708, "end_pos": 710, "annotation": "n_glycosylation_sequon" }, { "start_pos": 966, "end_pos": 968, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MUG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUG2" }, { "id": "SM01177", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01177" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Atos-like conserved", "eco_id": "ECO_0000259", "start_pos": 879, "end_pos": 937, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 202, "end_pos": 204 }, { "start_pos": 536, "end_pos": 538 }, { "start_pos": 610, "end_pos": 612 }, { "start_pos": 615, "end_pos": 617 }, { "start_pos": 708, "end_pos": 710 }, { "start_pos": 966, "end_pos": 968 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MUH0-1", "uniprot_ac": "A0A8C2MUH0", "uniprot_id": "A0A8C2MUH0_CRIGR", "mass": { "chemical_mass": 18560.0, "monoisotopic_mass": 18560.0 }, "refseq": { "ac": "XP_003495836", "name": "sperm acrosome membrane-associated protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495836" }, "gene_names": [ { "name": "Spaca3", "type": "recommended", "evidence": [ { "id": "A0A8C2MUH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH0" } ] }, { "name": "Spaca3", "type": "synonym", "evidence": [ { "id": "XP_003495836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495836" } ] } ], "protein_names": [ { "name": "Sperm acrosome membrane-associated protein 3", "type": "recommended", "evidence": [ { "id": "A0A8C2MUH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH0/entry#names_and_taxonomy" } ] }, { "name": "sperm acrosome membrane-associated protein 3", "type": "synonym", "evidence": [ { "id": "XP_003495836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495836" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003495836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495836" } ] }, { "annotation": "Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH0#function" }, { "database": "UniProtKB", "id": "ARBA00024656", "url": "https://www.uniprot.org/uniprotkb/ARBA00024656#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Spaca3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH0", "locus": {} } ], "crossref": [ { "id": "cd16897", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16897", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762682", "url": "https://www.ncbi.nlm.nih.gov/gene/100762682", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001916", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001916", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762682", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762682", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MYCTDLL", "url": "https://omabrowser.org/oma/group/MYCTDLL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MUH0", "url": "https://www.orthodb.org/?gene=A0A8C2MUH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11407", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11407", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11407:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11407:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00062", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00062", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003495836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495836", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MUH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEARIRAPRRQLCPPGITWLALAYLLSCLLASSKARVFSRCELAKELNDFGLDGYRGYNLADWICLAYYTSGFNTAAVDHEADGSTNNGIFQISSRKWCKNLSPNGPNICRMYCTDLLNYDLKNSVICAMKIVQEPQGLGYWEAWRQHCQGRDLRDWVDGCEF", "length": 163, "header": "tr|A0A8C2MUH0-1|A0A8C2MUH0_CRIGR Isoform 1 of Sperm acrosome membrane-associated protein 3 OS=Cricetulus griseus OX=10029 GN=Spaca3 PE=3 SV=1 CANONICAL=A0A8C2MUH0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MUH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH0/entry#A0A8C2MUH0-1", "sequence": { "sequence": "MEARIRAPRRQLCPPGITWLALAYLLSCLLASSKARVFSRCELAKELNDFGLDGYRGYNLADWICLAYYTSGFNTAAVDHEADGSTNNGIFQISSRKWCKNLSPNGPNICRMYCTDLLNYDLKNSVICAMKIVQEPQGLGYWEAWRQHCQGRDLRDWVDGCEF", "length": 163, "header": "tr|A0A8C2MUH0-1|A0A8C2MUH0_CRIGR Isoform 1 of Sperm acrosome membrane-associated protein 3 OS=Cricetulus griseus OX=10029 GN=Spaca3 PE=3 SV=1 CANONICAL=A0A8C2MUH0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762682", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762682", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TEC5-1", "protein_name": "Sperm acrosome membrane-associated protein 3", "gene_name": "SPACA3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEARSRAPRRRLCPPGIVLLTLASLLSCLLTSGQAKVYSRCELARLLQDVGLDGFRGYSLANWVCLAYFASGFNTAAVDHEADGSTNSGIFQINSRKWCRNLNPSVPNLCQMYCSDLLNPNLKDTIICAMKIAQDPKGLGTWEAWRHHCQGKDLTDWVDGCDL", "length": 163 }, "evidence": [ { "id": "A0A8C2MUH0", "url": "https://omabrowser.org/oma/group/A0A8C2MUH0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A6QQ77-1", "protein_name": "Sperm acrosome membrane-associated protein 3", "gene_name": "SPACA3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEAGSWAPRRWPRPPGIVLLALASVLSSLLSSGQARVYSRCELARVLQDFGLEGYRGYSLADWICLAYFASGFNTGAVDHEADGSTNSGIFQINSRKWCKNLNPNVPNLCQMYCSDLLNPNLKDTVICAMKITQEPQGLGSWEAWRHHCQGKDLSDWVDGCEL", "length": 163 }, "evidence": [ { "id": "A0A8C2MUH0", "url": "https://omabrowser.org/oma/group/A0A8C2MUH0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1M6E7-1", "protein_name": "Sperm acrosome membrane-associated protein 3", "gene_name": "Spaca3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEARSRAPRRQPCPPGITWLALAYLLSCLLASSKAKVFSRCELAKVLHDFGLEGYRGYNLADWICLAYYTSGFNTDAVDHEADGSTNNGIFQISSRKWCKNLAPNGPNLCRIYCTDLLSNDLKDSVACVMKIAQEPQGLGYWESWKHHCQGRDLSDWVDGCDF", "length": 163 }, "evidence": [ { "id": "A0A8C2MUH0", "url": "https://omabrowser.org/oma/group/A0A8C2MUH0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IXA5-1", "protein_name": "Sperm acrosome membrane-associated protein 3", "gene_name": "SPACA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSALRGAPLIRVHSSPVSSPSVSGPRRLVSCLSSQSSALSQSGGGSTSAAGIEARSRALRRRWCPAGIMLLALVCLLSCLLPSSEAKLYGRCELARVLHDFGLDGYRGYSLADWVCLAYFTSGFNAAALDYEADGSTNNGIFQINSRRWCSNLTPNVPNVCRMYCSDLLNPNLKDTVICAMKITQEPQGLGYWEAWRHHCQGKDLTEWVDGCDF", "length": 215 }, "evidence": [ { "id": "A0A8C2MUH0", "url": "https://omabrowser.org/oma/group/A0A8C2MUH0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D9X8-1", "protein_name": "Sperm acrosome membrane-associated protein 3", "gene_name": "Spaca3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. 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"https://www.ebi.ac.uk/interpro/entry/IPR004182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774042", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774042", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MUH3", "url": "https://www.orthodb.org/?gene=A0A8C2MUH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47666", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47666", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47666:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47666:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027261932", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261932", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MVW5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MVW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GT93", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GT93-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWVNPEEVLLANALWITERANPYFILQRRKGHGGDGGGGGGLAGLLVGTLDVVLDSSARVAPYRILYQTPDSLVYWTIACGGSRKEVTEHWEWLEQNLLQTLSIFENENDITTFVRGKIQGIIAEYNKINDVKEDDDTEKFKEVIVKFHRLFGMPEEEKLVNYYSCSYWKGKVPRQGWMYLSINHLCFSSFLMGREAKLVIRWVDITQLEKNATLLLPDVIKVNTRSSEHFFSVFLNINETFKLMEQLANIAMRQLLDNEGFEQDRSLPKLKKKSPKKVSALKRDLDARAKSERYRALFRLPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENLCSLIIPLREVTIVEKADSCSVLPSPLSISTRNRMTFLFANLKDRDFLVQRISDFLQQTTSRIYSDREFSGSCNSSDDEVYSRPSSLVSSSPQRSTSSDAEGERPFNFNGNSVPTATQTLMTMYRRRSPEEFNPKLAKEFLKEQAWKIHFAEYGQGICMYRTEKTRELVLKGIPESMRGELWLLLSGAINEKATHPGYYEDLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVISTISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLNCKDDGEAMTVLGRYLDSVTNKDSTLPPIPHLHSLLSDDVGPYPAVDIFRLIGTSYEKFGTIRADLIEQMRFKQRLKVIQTLEDTTKRNVVRTIVTETSFTIDELEELYALFKAEHLTSCYWGGSSNALDRHDPSLPYLEQYRIDFEQFKGMFVLLFPWACGTHSDVLASRLFQLLDENGDSLINFREFVSGLSAACHGDLTEKLKLLYKMHVLPEPSSDQDEPDSAFEATQYFFEDITPECTHVVGLDSRSKQGAEDGFVTVSLKQDKGKRANSQENRNYLKLWTAENKSKSKNAKDLPKLNQGQFIELCKTMYNMFSEDPNEQELYHATAAVTSLLLEIGEVGKFFITQPVKEDGVTGPPCSQAIPGMLFPKKGPSQPYTVESTEPLPTSLAVDSEEHSLGGQMEDIKLEDSSPRDNGACSSMLISDDDTKDDSSMSSYSVLSAGSHEEDKLHCEDIGEDTVLVRSSQGTATLPRSSSLDRDWAITFEQFLASLLTEPALVKYFDKPVCMMARVTSAKNMRMMGKPLTSASDYEISALSG", "length": 1264, "header": "tr|A0A8C2MUH3-1|A0A8C2MUH3_CRIGR Isoform 1 of TBC1 domain family member 9 OS=Cricetulus griseus OX=10029 GN=Tbc1d9 PE=4 SV=1 CANONICAL=A0A8C2MUH3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MUH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH3/entry#A0A8C2MUH3-1", "sequence": { "sequence": "MWVNPEEVLLANALWITERANPYFILQRRKGHGGDGGGGGGLAGLLVGTLDVVLDSSARVAPYRILYQTPDSLVYWTIACGGSRKEVTEHWEWLEQNLLQTLSIFENENDITTFVRGKIQGIIAEYNKINDVKEDDDTEKFKEVIVKFHRLFGMPEEEKLVNYYSCSYWKGKVPRQGWMYLSINHLCFSSFLMGREAKLVIRWVDITQLEKNATLLLPDVIKVNTRSSEHFFSVFLNINETFKLMEQLANIAMRQLLDNEGFEQDRSLPKLKKKSPKKVSALKRDLDARAKSERYRALFRLPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENLCSLIIPLREVTIVEKADSCSVLPSPLSISTRNRMTFLFANLKDRDFLVQRISDFLQQTTSRIYSDREFSGSCNSSDDEVYSRPSSLVSSSPQRSTSSDAEGERPFNFNGNSVPTATQTLMTMYRRRSPEEFNPKLAKEFLKEQAWKIHFAEYGQGICMYRTEKTRELVLKGIPESMRGELWLLLSGAINEKATHPGYYEDLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVISTISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLNCKDDGEAMTVLGRYLDSVTNKDSTLPPIPHLHSLLSDDVGPYPAVDIFRLIGTSYEKFGTIRADLIEQMRFKQRLKVIQTLEDTTKRNVVRTIVTETSFTIDELEELYALFKAEHLTSCYWGGSSNALDRHDPSLPYLEQYRIDFEQFKGMFVLLFPWACGTHSDVLASRLFQLLDENGDSLINFREFVSGLSAACHGDLTEKLKLLYKMHVLPEPSSDQDEPDSAFEATQYFFEDITPECTHVVGLDSRSKQGAEDGFVTVSLKQDKGKRANSQENRNYLKLWTAENKSKSKNAKDLPKLNQGQFIELCKTMYNMFSEDPNEQELYHATAAVTSLLLEIGEVGKFFITQPVKEDGVTGPPCSQAIPGMLFPKKGPSQPYTVESTEPLPTSLAVDSEEHSLGGQMEDIKLEDSSPRDNGACSSMLISDDDTKDDSSMSSYSVLSAGSHEEDKLHCEDIGEDTVLVRSSQGTATLPRSSSLDRDWAITFEQFLASLLTEPALVKYFDKPVCMMARVTSAKNMRMMGKPLTSASDYEISALSG", "length": 1264, "header": "tr|A0A8C2MUH3-1|A0A8C2MUH3_CRIGR Isoform 1 of TBC1 domain family member 9 OS=Cricetulus griseus OX=10029 GN=Tbc1d9 PE=4 SV=1 CANONICAL=A0A8C2MUH3-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MVW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH3/entry#A0A8C2MVW5-1", "sequence": { "sequence": "MWVNPEEVLLANALWITERANPYFILQRRKGHGGDGGGGGGLAGLLVGTLDVVLDSSARVAPYRILYQTPDSLVYWTIACGGSRKEVTEHWEWLEQNLLQTLSIFENENDITTFVRGKIQVTIVEKADSCSVLPSPLSISTRNRMTFLFANLKDRDFLVQRISDFLQQTTSRIYSDREFSGSCNSSDDEVYSRPSSLVSSSPQRSTSSDAEGERPFNFNGNSVPTATQTLMTMYRRRSPEEFNPKLAKEFLKEQAWKIHFAEYGQGICMYRTEKTRELVLKGIPESMRGELWLLLSGAINEKATHPGYYEDLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVISTISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLNCKDDGEAMTVLGRYLDSVTNKDSTLPPIPHLHSLLSDDVGPYPAVDIFRLIGTSYEKFGTIRADLIEQMRFKQRLKVIQTLEDTTKRNVVRTIVTETSFTIDELEELYALFKAEHLTSCYWGGSSNALDRHDPSLPYLEQYRIDFEQFKGMFVLLFPWACGTHSDVLASRLFQLLDENGDSLINFREFVSGLSAACHGDLTEKLKLLYKMHVLPEPSSDQDEPDSAFEATQYFFEDITPECTHVVGLDSRSKQGAEDGFVTVSLKQDKGKRANSQENRNYLKLWTAENKSKSKNAKDLPKLNQGQFIELCKTMYNMFSEDPNEQELYHATAAVTSLLLEIGEVGKFFITQPVKEDGVTGPPCSQAIPGMLFPKKGPSQPYTVESTEPLPTSLAVDSEEHSLGGQMEDIKLEDSSPRDNGACSSMLISDDDTKDDSSMSSYSVLSAGSHEEDKLHCEDIGEDTVLVRSSQGTATLPRSSSLDRDWAITFEQFLASLLTEPALVKYFDKPVCMMARVTSAKNMRMMGKPLTSASDYEISALSG", "length": 1031, "header": "tr|A0A8C2MVW5-1|A0A8C2MUH3_CRIGR Computationally mapped isoform of TBC1 domain family member 9 OS=Cricetulus griseus OX=10029 GN=Tbc1d9 PE=4 SV=1 CANONICAL=A0A8C2MUH3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GT93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH3/entry#A0A9J7GT93-1", "sequence": { "sequence": "MWVNPEEVLLANALWITERANPYFILQRRKGHGGDGGGGGGLAGLLVGTLDVVLDSSARVAPYRILYQTPDSLVYWTIACGGSRKEVTEHWEWLEQNLLQTLSIFENENDITTFVRGKIQGIIAEYNKINDVKEDDDTEKFKEVIVKFHRLFGMPEEEKLVNYYSCSYWKGKVPRQGWMYLSINHLCFSSFLMGREAKLVIRWVDITQLEKNATLLLPDVIKVNTRSSEHFFSVFLNINETFKLMEQLANIAMRQLLDNEGFEQDRSLPKLKKKSPKKVSALKRDLDARAKSERYRALFRLPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENLCSLIIPLREVTIVEKADSCSVLPSPLSISTRNRMTFLFANLKDRDFLVQRISDFLQQTTSRIYSDREFSGSCNSSDDEVYSRPSSLVSSSPQRSTSSDAEGERPFNFNGNSVPTATQTLMTMYRRRSPEEFNPKLAKEFLKEQAWKIHFAEYGQGICMYRTEKTRELVLKGIPESMRGELWLLLSGAINEKATHPGYYEDLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVISTISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLNCKDDGEAMTVLGRYLDSVTNKDSTLPPIPHLHSLLSDDVGPYPAVDIFRLIGTSYEKFGTIRADLIEQMRFKQRLKVIQTLEDTTKRNVAEHLTSCYWGGSSNALDRHDPSLPYLEQYRIDFEQFKGMFVLLFPWACGTHSDVLASRLFQLLDENGDSLINFREFVSGLSAACHGDLTEKLKLLYKMHVLPEPSSDQDEPDSAFEATQYFFEDITPECTHVVGLDSRSKQGAEDGFVTVSLKQDKGKRANSQENRNYLKLWTAENKSKSKNAKDLPKLNQGQFIELCKTMYNMFSEDPNEQELYHATAAVTSLLLEIGEVGKFFITQPVKEDGVTGPPCSQAIPGMLFPKKGPSQPYTVESTEPLPTSLAVDSEEHSLGGQMEDIKLEDSSPRDNGACSSMLISDDDTKDDSSMSSYSVLSAGSHEEDKLHCEDIGEDTVLVRSSQGTATLPRSSSLDRDWAITFEQFLASLLTEPALVKYFDKPVCMMARVTSAKNMRMMGKPLTSASDYEISALSG", "length": 1241, "header": "tr|A0A9J7GT93-1|A0A9J7GT93_CRIGR Computationally mapped isoform of TBC1 domain family member 9 OS=Cricetulus griseus OX=10029 GN=Tbc1d9 PE=4 SV=1 CANONICAL=A0A8C2MUH3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVW5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVW5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVW5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVW5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774042", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774042", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH3" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "system process", "id": "GO:0003008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003008", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1011, "end_pos": 1013, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MUH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH3" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 886, "end_pos": 921, "start_aa": "His", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MUH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUH3" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 515, "end_pos": 702, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1011, "end_pos": 1013 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 239, "end_pos": 241 }, { "start_pos": 417, "end_pos": 419 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MUJ0-1", "uniprot_ac": "A0A8C2MUJ0", "uniprot_id": "A0A8C2MUJ0_CRIGR", "mass": { "chemical_mass": 28159.0, "monoisotopic_mass": 28159.0 }, "refseq": { "ac": "XP_027283011", "name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283011" }, "gene_names": [ { "name": "Pigl", "type": "recommended", "evidence": [ { "id": "A0A8C2MUJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0" } ] }, { "name": "Pigl", "type": "synonym", "evidence": [ { "id": "XP_027283011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283011" } ] } ], "protein_names": [ { "name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "type": "recommended", "evidence": [ { "id": "A0A8C2MUJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0/entry#names_and_taxonomy" } ] }, { "name": "3.5.1.89", "type": "synonym", "evidence": [ { "id": "A0A8C2MUJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0/entry#names_and_taxonomy" } ] }, { "name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027283011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283011" } ] }, { "name": "Phosphatidylinositol-glycan biosynthesis class L protein", "type": "synonym", "evidence": [ { "id": "A0A8C2MUJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283011" } ] }, { "annotation": "Catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis, which is the de-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0#function" }, { "database": "UniProtKB", "id": "ARBA00060114", "url": "https://www.uniprot.org/uniprotkb/ARBA00060114#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pigl", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0", "locus": {} } ], "crossref": [ { "id": "100752487", "url": "https://www.ncbi.nlm.nih.gov/gene/100752487", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003737", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003737", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752487", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752487", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MUJ0", "url": "https://www.orthodb.org/?gene=A0A8C2MUJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12993", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12993", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12993:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12993:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027283011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283011", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11660", "url": "https://www.rhea-db.org/rhea/11660", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MUJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVVGLLCLVVAVLTWGFLRVRDAAKRMKSPEQAGLLGAGSRALLVIAHPDDEAMFFAPTVLGLARLELRVFLLCFSAGNYYNQGEIRKKELLQSCDVLGIPPSRVTIIDNSKFPDDPGVQWDTECVASTLLQHIDVNGIDLVVTFDAEGVSGHSNHIALYRAVRALHSEGKLPKGCSVLTLKSVNVLRKYLYPLDLPWSLLSPHDVLFQLTSKEVAQAKKAMSCHHSQLLWFRHLYVIFSRYMRINSLQFL", "length": 252, "header": "tr|A0A8C2MUJ0-1|A0A8C2MUJ0_CRIGR Isoform 1 of N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase OS=Cricetulus griseus OX=10029 GN=Pigl PE=3 SV=1 CANONICAL=A0A8C2MUJ0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MUJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0/entry#A0A8C2MUJ0-1", "sequence": { "sequence": "MEVVGLLCLVVAVLTWGFLRVRDAAKRMKSPEQAGLLGAGSRALLVIAHPDDEAMFFAPTVLGLARLELRVFLLCFSAGNYYNQGEIRKKELLQSCDVLGIPPSRVTIIDNSKFPDDPGVQWDTECVASTLLQHIDVNGIDLVVTFDAEGVSGHSNHIALYRAVRALHSEGKLPKGCSVLTLKSVNVLRKYLYPLDLPWSLLSPHDVLFQLTSKEVAQAKKAMSCHHSQLLWFRHLYVIFSRYMRINSLQFL", "length": 252, "header": "tr|A0A8C2MUJ0-1|A0A8C2MUJ0_CRIGR Isoform 1 of N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase OS=Cricetulus griseus OX=10029 GN=Pigl PE=3 SV=1 CANONICAL=A0A8C2MUJ0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752487", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752487", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "N-acetylglucosaminylphosphatidylinositol deacetylase activity", "id": "GO:0000225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000225", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11660", "name": "", "equation": "a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + H2O = a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + acetate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8C2MUJ0-1" ], "evidence": [ { "id": "11660", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11660" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8C2MUJ0", "gene_name": "Pigl", "activity": [ { "ec_number": "3.5.1.89", "activity": "a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + H2O = a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + acetate.", "evidence": [ { "id": "A0A8C2MUJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0" } ] }, { "ec_number": "3.5.1.89", "activity": "", "evidence": [ { "id": "A0A8C2MUJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUJ0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.1.89", "ec_name": "a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + H2O = a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + acetate.", "evidence": [ { "id": "3.5.1.89", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.89" }, { "id": "3.5.1.89", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.1.89" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MUL3-1", "uniprot_ac": "A0A8C2MUL3", "uniprot_id": "A0A8C2MUL3_CRIGR", "mass": { "chemical_mass": 42489.0, "monoisotopic_mass": 42489.0 }, "refseq": { "ac": "XP_016830232", "name": "alpha-1,3-galactosyltransferase 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830232" }, "gene_names": [ { "name": "A3galt2", "type": "recommended", "evidence": [ { "id": "A0A8C2MUL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3" } ] }, { "name": "A3galt2", "type": "synonym", "evidence": [ { "id": "XP_016830232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830232" } ] } ], "protein_names": [ { "name": "Alpha-1,3-galactosyltransferase 2", "type": "synonym", "evidence": [ { "id": "A0A8C2MUL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3/entry#names_and_taxonomy" } ] }, { "name": "alpha-1,3-galactosyltransferase 2", "type": "synonym", "evidence": [ { "id": "XP_016830232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830232" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613801.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016830232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830232" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "A3galt2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3", "locus": {} } ], "crossref": [ { "id": "cd02515", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02515", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774283", "url": "https://www.ncbi.nlm.nih.gov/gene/100774283", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774283", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774283", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MUL3", "url": "https://www.orthodb.org/?gene=A0A8C2MUL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10462", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10462", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10462:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10462:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016830232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830232", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MUL3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLRGLGALGSHGGFRKQEGQRQRGQGKPTWGLPRTKKRLLWMPLLSAFGCLALYLYGFRILRYLEGAIPMGICPIATTPLLTDKFTGVLRHWARSEVPTCTSWGAPIIWDSTFDPHVAKQEVRRRNLTIGLTVFAVGRYLEKYLERFLKSAEQHFMVGQRVVFYVFTDRPEAVPYMTLGQGRLLRVEPVQRESRWQDVSMARMRVLYEALGGKLGQEADYVFCLDVDQRFTGNFGPEVLADLVAQLHSWHYHWPRWLLPYERDKRSAAALSWGEGDFYYHAALFGGSVAALRKLTAHCALGQQLDRERGIEAVWHDESHLNKFFWLYKPTKLLSPEFCWDPKIGWRTDIHHPRLIWEPKEYALVRN", "length": 367, "header": "tr|A0A8C2MUL3-1|A0A8C2MUL3_CRIGR Isoform 1 of Alpha-1,3-galactosyltransferase 2 OS=Cricetulus griseus OX=10029 GN=A3galt2 PE=3 SV=1 CANONICAL=A0A8C2MUL3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MUL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3/entry#A0A8C2MUL3-1", "sequence": { "sequence": "MPLRGLGALGSHGGFRKQEGQRQRGQGKPTWGLPRTKKRLLWMPLLSAFGCLALYLYGFRILRYLEGAIPMGICPIATTPLLTDKFTGVLRHWARSEVPTCTSWGAPIIWDSTFDPHVAKQEVRRRNLTIGLTVFAVGRYLEKYLERFLKSAEQHFMVGQRVVFYVFTDRPEAVPYMTLGQGRLLRVEPVQRESRWQDVSMARMRVLYEALGGKLGQEADYVFCLDVDQRFTGNFGPEVLADLVAQLHSWHYHWPRWLLPYERDKRSAAALSWGEGDFYYHAALFGGSVAALRKLTAHCALGQQLDRERGIEAVWHDESHLNKFFWLYKPTKLLSPEFCWDPKIGWRTDIHHPRLIWEPKEYALVRN", "length": 367, "header": "tr|A0A8C2MUL3-1|A0A8C2MUL3_CRIGR Isoform 1 of Alpha-1,3-galactosyltransferase 2 OS=Cricetulus griseus OX=10029 GN=A3galt2 PE=3 SV=1 CANONICAL=A0A8C2MUL3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774283", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774283", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3" } ], "pmid": "" }, { "name": "alpha-1,3-galactosyltransferase activity", "id": "GO:0001962", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001962", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A8C2MUL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3#function" }, { "id": "A0A8C2MUL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL3" }, { "id": "PIRSR605076-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR605076-3" } ], "binding_site_uniprot": 226, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", 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[], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 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{ "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027263106", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263106" } ] }, { "annotation": "Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FM25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FM25#function" }, { "database": "UniProtKB", "id": "RU367072", "url": "https://www.uniprot.org/uniprotkb/RU367072#function" }, { "database": "UniProtKB", "id": "A0A9J7JJS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJS7#function" }, { "database": "UniProtKB", "id": "A0A8C2MUL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4#function" }, { "database": "UniProtKB", "id": "A0A9J7JD63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD63#function" }, { "database": "UniProtKB", "id": "A0A9J7GRE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRE9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766371", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766371", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MUL4", "url": "https://www.orthodb.org/?gene=A0A8C2MUL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JD63", "url": "https://www.orthodb.org/?gene=A0A9J7JD63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12891", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12891", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12891:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12891:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12460", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12460", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14500", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14500", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027263106", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263106", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MUL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FM25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FM25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FM25-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FM25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GRE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GRE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JD63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JD63-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAATALEEAAAPLDALCGLVQDFVMGQQEGPADQVAADVKSGVYTVLQVVEALGSSLENPEPRTRARGIQLLSRVLLQCHSLLLEKEVVHLILFYENRLKDHHLVIPSVLQGLRALSLSVALPPGLAVSVLKAIFQEVHVQSLLQVDRHTVFSIITNFMRSREEELKGLGADFTFGFIQVMDGEKDPRNLLVAFRIVHDLISKDYSLGPFVEELFEVTSCYFPIDFTPPPNDPYGIQRDDLILSLRAVLASTPRFAEFLLPLLIEKVDSEILSAKLDSLQTLNACCSVYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSCSVLRADAEDLLDSFLSNILQDCRHHLCEPDMKLVWPSAKLLQAAAGASARACEHITSTVLPLLLEQFHKHSQSNQRRTILEMILGFLKLQQKWSYEDKDERPLTRFKDQLCSLVFMALTDPSTQLQLVGIRTLTVLGSQPDLLSSGDLELAVGHLYRLSFLEEDSESCRVAALEASGTLTTLYPGAFSSHLLPKLAKELHKGKSDVAREDGLMKCSRHFCCLQALSAISTHPSIVRETLPLLLQRLCQANKGNVVTESSEVIAICQSLQQVAEKCQQDPESYWYFHETAIPCLFGLAVQASMPEKESSVLRKVLLEDEVLAALASVIGTATTHLSPELAAQSVTCIVPLFLDGNTSFLPENSFPSRFQPFQDGSSAQRRLVALLTAFVCSLPRNVEIPQLNQLMRELLEQSCCHSCPFASTAAAKCFAGLLNKQPPGQQLDEFLQLAVDTVETGLASGSSRNQAFVLLLWVTKALVLRYHPLSACLTTRLMGLLSDPELGPAAADGFSLLMSDCTDVLTRAGHADVRIMFRQRFFTDNVPALVQGFHAAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTLLSLLLEALSCHDSVVQLSTLSCLQPLLLESPQIMSLHIDTLVTKFLTLSSSHSMAVRIAALQCMHALTRLPAPVLLPYKSQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS", "length": 1031, "header": "tr|A0A8C2MUL4-1|A0A8C2MUL4_CRIGR Isoform 1 of MMS19 nucleotide excision repair protein OS=Cricetulus griseus OX=10029 GN=Mms19 PE=3 SV=1 CANONICAL=A0A8C2MUL4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MUL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4/entry#A0A8C2MUL4-1", "sequence": { "sequence": "MAAATALEEAAAPLDALCGLVQDFVMGQQEGPADQVAADVKSGVYTVLQVVEALGSSLENPEPRTRARGIQLLSRVLLQCHSLLLEKEVVHLILFYENRLKDHHLVIPSVLQGLRALSLSVALPPGLAVSVLKAIFQEVHVQSLLQVDRHTVFSIITNFMRSREEELKGLGADFTFGFIQVMDGEKDPRNLLVAFRIVHDLISKDYSLGPFVEELFEVTSCYFPIDFTPPPNDPYGIQRDDLILSLRAVLASTPRFAEFLLPLLIEKVDSEILSAKLDSLQTLNACCSVYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSCSVLRADAEDLLDSFLSNILQDCRHHLCEPDMKLVWPSAKLLQAAAGASARACEHITSTVLPLLLEQFHKHSQSNQRRTILEMILGFLKLQQKWSYEDKDERPLTRFKDQLCSLVFMALTDPSTQLQLVGIRTLTVLGSQPDLLSSGDLELAVGHLYRLSFLEEDSESCRVAALEASGTLTTLYPGAFSSHLLPKLAKELHKGKSDVAREDGLMKCSRHFCCLQALSAISTHPSIVRETLPLLLQRLCQANKGNVVTESSEVIAICQSLQQVAEKCQQDPESYWYFHETAIPCLFGLAVQASMPEKESSVLRKVLLEDEVLAALASVIGTATTHLSPELAAQSVTCIVPLFLDGNTSFLPENSFPSRFQPFQDGSSAQRRLVALLTAFVCSLPRNVEIPQLNQLMRELLEQSCCHSCPFASTAAAKCFAGLLNKQPPGQQLDEFLQLAVDTVETGLASGSSRNQAFVLLLWVTKALVLRYHPLSACLTTRLMGLLSDPELGPAAADGFSLLMSDCTDVLTRAGHADVRIMFRQRFFTDNVPALVQGFHAAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTLLSLLLEALSCHDSVVQLSTLSCLQPLLLESPQIMSLHIDTLVTKFLTLSSSHSMAVRIAALQCMHALTRLPAPVLLPYKSQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS", "length": 1031, "header": "tr|A0A8C2MUL4-1|A0A8C2MUL4_CRIGR Isoform 1 of MMS19 nucleotide excision repair protein OS=Cricetulus griseus OX=10029 GN=Mms19 PE=3 SV=1 CANONICAL=A0A8C2MUL4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FM25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4/entry#A0A9J7FM25-1", "sequence": { "sequence": "MAAATALEEAAAPLDALCGLVQDFVMGQQEGPADQVAADVKSGVYTVLQVVEALGSSLENPEPRTRARGIQLLSRVLLQCHSLLLEKEVVHLILFYENRLKDHHLVIPSVLQGLRALSLSVALPPGLAVSVLKAIFQEVHVQSLLQVDRHTVFSIITNFMRSREEELKGLGADFTFGFIQVMDGEKDPRNLLVAFRIVHDLISKDYSLGPFVEELFEVTSCYFPIDFTPPPNDPYGIQRDDLILSLRAVLASTPRFAEFLLPLLIEKVDSEILSAKLDSLQTLNACCSVYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSCSVLRADAEDLLDSFLSNILQDCRHHLCEPDMKLVWPSAKLLQAAAGASARACEHITSTVLPLLLEQFHKHSQSNQRRTILEMILGFLKLQQKWSYEDKDERPLTRFKDQLCSLVFMALTDPSTQLQLVGIRTLTVLGSQPDLLSSGDLELAVGHLYRLSFLEEDSESWVAALEASGTLTTLYPGAFSSHLLPKLAKELHKGKSDVAREDGLMKCSRHFCCLQALSAISTHPSIVRETLPLLLQRLCQANKGNVVTESSEVIAICQSLQQVAEKCQQDPESYWYFHETAIPCLFGLAVQASMPEKESSVLRKVLLEDEVLAALASVIGTATTHLSPELAAQSVTCIVPLFLDGNTSFLPENSFPSRFQPFQDGSSAQRRLVALLTAFVCSLPRNVEIPQLNQLMRELLEQSCCHSCPFASTAAAKCFAGLLNKQPPGQQLDEFLQLAVDTVETGLASGSSRNQAFVLLLWVTKALVLRYHPLSACLTTRLMGLLSDPELGPAAADGFSLLMSDCTDVLTRAGHADVRIMFRQRFFTDNVPALVQGFHAAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTLLSLLLEALSCHDSVVQLSTLSCLQPLLLESPQIMSLHIDTLVTKFLTLSSSHSMAVRIAALQCMHALTRLPAPVLLPYKSQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS", "length": 1030, "header": "tr|A0A9J7FM25-1|A0A8C2MUL4_CRIGR Computationally mapped isoform of MMS19 nucleotide excision repair protein OS=Cricetulus griseus OX=10029 GN=Mms19 PE=3 SV=1 CANONICAL=A0A8C2MUL4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GRE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4/entry#A0A9J7GRE9-1", "sequence": { "sequence": "MRSREEELKGLGADFTFGFIQVMDGEKDPRNLLVAFRIVHDLISKDYSLGPFVEELFEVTSCYFPIDFTPPPNDPYGIQRDDLILSLRAVLASTPRFAEFLLPLLIEKVDSEILSAKLDSLQTLNACCSVYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSCSVLRADAEDLLDSFLSNILQDCRHHLCEPDMKLVWPSAKLLQAAAGASARACEHITSTVLPLLLEQFHKHSQSNQRRTILEMILGFLKLQQKWSYEDKDERPLTRFKDQLCSLVFMALTDPSTQLQLVGIRTLTVLGSQPDLLSSGDLELAVGHLYRLSFLEEDSESCRVAALEASGTLTTLYPGAFSSHLLPKLAKELHKGKSDVAREDGLMKCSRHFCCLQALSAISTHPSIVRETLPLLLQRLCQANKGNVVTESSEVIAICQSLQQVAEKCQQDPESYWYFHETAIPCLFGLAVQASMPEKESSVLRKVLLEDEVLAALASVIGTATTHLSPELAAQSVTCIVPLFLDGNTSFLPENSFPSRFQPFQDGSSAQRRLVALLTAFVCSLPRNVEIPQLNQLMRELLEQSCCHSCPFASTAAAKCFAGLLNKQPPGQQLDEFLQLAVDTVETGLASGSSRNQAFVLLLWVTKALVLRYHPLSACLTTRLMGLLSDPELGPAAADGFSLLMSDCTDVLTRAGHADVRIMFRQRFFTDNVPALVQGFHAAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTLLSLLLEALSCHDSVVQLSTLSCLQPLLLESPQIMSLHIDTLVTKFLTLSSSHSMAVRIAALQCMHALTRLPAPVLLPYKSQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS", "length": 872, "header": "tr|A0A9J7GRE9-1|A0A9J7GRE9_CRIGR Computationally mapped isoform of MMS19 nucleotide excision repair protein OS=Cricetulus griseus OX=10029 GN=Mms19 PE=3 SV=1 CANONICAL=A0A8C2MUL4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JD63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4/entry#A0A9J7JD63-1", "sequence": { "sequence": "MYSPCYKWIAIQCSVSSLTSCDHGKKVMDGEKDPRNLLVAFRIVHDLISKDYSLGPFVEELFEVTSCYFPIDFTPPPNDPYGIQRDDLILSLRAVLASTPRFAEFLLPLLIEKVDSEILSAKLDSLQTLNACCSVYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSCSVLRADAEDLLDSFLSNILQDCRHHLCEPDMKLVWPSAKLLQAAAGASARACEHITSTVLPLLLEQFHKHSQSNQRRTILEMILGFLKLQQKWSYEDKDERPLTRFKDQLCSLVFMALTDPSTQLQLVGIRTLTVLGSQPDLLSSGDLELAVGHLYRLSFLEEDSESCRVAALEASGTLTTLYPGAFSSHLLPKLAKELHKGKSDVAREDGLMKCSRHFCCLQALSAISTHPSIVRETLPLLLQRLCQANKGNVVTESSEVIAICQSLQQVAEKCQQDPESYWYFHETAIPCLFGLAVQASMPEKESSVLRKVLLEDEVLAALASVIGTATTHLSPELAAQSVTCIVPLFLDGNTSFLPENSFPSRFQPFQDGSSAQRRLVALLTAFVCSLPRNVEIPQLNQLMRELLEQSCCHSCPFASTAAAKCFAGLLNKQPPGQQLDEFLQLAVDTVETGLASGSSRNQAFVLLLWVTKALVLRYHPLSACLTTRLMGLLSDPELGPAAADGFSLLMSDCTDVLTRAGHADVRIMFRQRFFTDNVPALVQGFHAAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTLLSLLLEALSCHDSVVQLSTLSCLQPLLLESPQIMSLHIDTLVTKFLTLSSSHSMAVRIAALQCMHALTRLPAPVLLPYKSQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS", "length": 877, "header": "tr|A0A9J7JD63-1|A0A9J7JD63_CRIGR Computationally mapped isoform of MMS19 nucleotide excision repair protein OS=Cricetulus griseus OX=10029 GN=Mms19 PE=3 SV=1 CANONICAL=A0A8C2MUL4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4/entry#A0A9J7JJS7-1", "sequence": { "sequence": "MKLVWPSAKLLQAAAGASARACEHITSTVLPLLLEQFHKHSQSNQRRTILEMILGFLKLQQKWSYEDKDERPLTRFKDQLCSLVFMALTDPSTQLQLVGIRTLTVLGSQPDLLSSGDLELAVGHLYRLSFLEEDSESCRVAALEASGTLTTLYPGAFSSHLLPKLAKELHKGKSDVAREDGLMKCSRHFCCLQALSAISTHPSIVRETLPLLLQRLCQANKGNVVTESSEVIAICQSLQQVAEKCQQDPESYWYFHETAIPCLFGLAVQASMPEKESSVLRKVLLEDEVLAALASVIGTATTHLSPELAAQSVTCIVPLFLDGNTSFLPENSFPSRFQPFQDGSSAQRRLVALLTAFVCSLPRNVEIPQLNQLMRELLEQSCCHSCPFASTAAAKCFAGLLNKQPPGQQLDEFLQLAVDTVETGLASGSSRNQAFVLLLWVTKALVLRYHPLSACLTTRLMGLLSDPELGPAAADGFSLLMSDCTDVLTRAGHADVRIMFRQRFFTDNVPALVQGFHAAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTLLSLLLEALSCHDSVVQLSTLSCLQPLLLESPQIMSLHIDTLVTKFLTLSSSHSMAVRIAALQCMHALTRLPAPVLLPYKSQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS", "length": 666, "header": "tr|A0A9J7JJS7-1|A0A8C2MUL4_CRIGR Computationally mapped isoform of MMS19 nucleotide excision repair protein OS=Cricetulus griseus OX=10029 GN=Mms19 PE=3 SV=1 CANONICAL=A0A8C2MUL4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FM25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FM25" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FM25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FM25" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766371", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766371", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosolic [4Fe-4S] assembly targeting complex", "id": "GO:0097361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097361", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4" } ], "pmid": "" }, { "name": "MMXD complex", "id": "GO:0071817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071817", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4" } ], "pmid": "" }, { "name": "nuclear estrogen receptor binding", "id": "GO:0030331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030331", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 689, "end_pos": 691, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MUL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4" }, { "id": "PF12460", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12460" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MMS19 C-terminal", "eco_id": "ECO_0000259", "start_pos": 556, "end_pos": 983, "start_aa": "Cys", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MUL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUL4" }, { "id": "PF14500", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14500" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MMS19 N-terminal", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 312, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 689, "end_pos": 691 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MUN7-1", "uniprot_ac": "A0A8C2MUN7", "uniprot_id": "A0A8C2MUN7_CRIGR", "mass": { "chemical_mass": 158590.0, "monoisotopic_mass": 158590.0 }, "refseq": { "ac": "XP_003501472", "name": "FYVE, RhoGEF and PH domain-containing protein 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501472" }, "gene_names": [ { "name": "Fgd6", "type": "recommended", "evidence": [ { "id": "A0A8C2MUN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUN7" } ] }, { "name": "Fgd6", "type": "synonym", "evidence": [ { "id": "XP_003501472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501472" } ] } ], "protein_names": [ { "name": "FYVE, RhoGEF and PH domain-containing protein 6", "type": "recommended", "evidence": [ { "id": "A0A8C2MUN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUN7/entry#names_and_taxonomy" } ] }, { "name": "FYVE, RhoGEF and PH domain-containing protein 6", "type": "synonym", "evidence": [ { "id": "XP_003501472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501472" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613849.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003501472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501472" } ] }, { "annotation": "May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUN7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUN7#function" }, { "database": "UniProtKB", "id": "ARBA00056020", "url": "https://www.uniprot.org/uniprotkb/ARBA00056020#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUN7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUN7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fgd6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUN7", "locus": {} } ], "crossref": [ { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13237", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13237", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15743", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15743", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756530", "url": "https://www.ncbi.nlm.nih.gov/gene/100756530", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756530", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756530", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PMSSCKF", "url": "https://omabrowser.org/oma/group/PMSSCKF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MUN7", "url": "https://www.orthodb.org/?gene=A0A8C2MUN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12673", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12673", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12673:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12673:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003501472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501472", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MUN7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSAAELKKPPLAPKPKLMGTNNKPQPPPIAPKPDIMNASVPRLTQKTKPTIAPKPKALTNSVVQDIKQSPSKKIPLNLGEREPELPESTDKFNCKDVRDPHSDYILPTCSCSSGCIQEPGSRESLCAKQLVLEPLGMKDNLGNNKNGESSLTAKRGTKWDSSGEKGQSQSGVILKASILEEKLKEVLTRQQSPCSSPRKHRSPYNTEMNGDYSCSRQIRIEFADLSPSLSSFEKVPAHHSCQLQLPRDESQNLETCHTGNSKSNSHFHSCELNDRKMSSDGTSKKTEVTDLGPLEIHLLPYTSKFPTPKPRRTHTARLLRQKYVDTPSESTEEPENSNNGSSCLLENSLKNNQVSVLHQVLYNQGQVDKVKPANKRAVTSDSKSDRQDSVNSQKAVRHETSSSEKVAPVLDADSILGPDSTAEDVSGMLPAVDKEISFIQCNTQSESLPKQVKLSCTEHPPTTCNVELSVPQIQKEPSSKIVPKKPQRHSLPTAGVLKKAASEELVEKNSYSSRKATNSEKGLERNHFQHLGPSSRGISSSSFDTPNSTSEKPVWKLPHPILPFSGSPESLKRVTLSLNNEPSISLTKPRAKSLSAVDMDRCNKPCKELPKKTSFKKLINVKLSIGFIKSDFQKFRSKSYQQADVTTGHLLSREPKKLESDWQGLVTGEEKRSKPIKAYSAENCSLESQKVKSWGQTSAANGQRAESLDDQLLSRDSSCQVSYKSSTSGCVPEYENVCHYEEIPEYENLPFVTAGGKTPELGWQNSSSAEDTDANLYEVEEPYDAPDGQLQLDPRHQPSSSGTPKEGQDDLNLGLGDLPSDEEVINSSDEDDVSSESSKGEPDPMEDKQGEDTGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLSWNEQQRIADIFVKKGPYLKMYSTYIKEFDKNIALLDEQCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLLEDSVDHRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLSGHHEIVQPGRVFLKEGILMKLSRKVMQPRMFFLFNDALLYTTPMQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSATERDDWLEAISRSIEEYAKKKITFCPSRSLDEDSEKKEEVSPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKRQLARVCEHCFQELQKLDHQLPPRIGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSTMSGYLYRSKGSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVTQVKDENSESKVFQLLHKGMVFYVFKADDAHSTQKWIEAFQEGTIL", "length": 1417, "header": "tr|A0A8C2MUN7-1|A0A8C2MUN7_CRIGR Isoform 1 of FYVE, RhoGEF and PH domain-containing protein 6 OS=Cricetulus griseus OX=10029 GN=Fgd6 PE=4 SV=1 CANONICAL=A0A8C2MUN7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MUN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUN7/entry#A0A8C2MUN7-1", "sequence": { "sequence": "MTSAAELKKPPLAPKPKLMGTNNKPQPPPIAPKPDIMNASVPRLTQKTKPTIAPKPKALTNSVVQDIKQSPSKKIPLNLGEREPELPESTDKFNCKDVRDPHSDYILPTCSCSSGCIQEPGSRESLCAKQLVLEPLGMKDNLGNNKNGESSLTAKRGTKWDSSGEKGQSQSGVILKASILEEKLKEVLTRQQSPCSSPRKHRSPYNTEMNGDYSCSRQIRIEFADLSPSLSSFEKVPAHHSCQLQLPRDESQNLETCHTGNSKSNSHFHSCELNDRKMSSDGTSKKTEVTDLGPLEIHLLPYTSKFPTPKPRRTHTARLLRQKYVDTPSESTEEPENSNNGSSCLLENSLKNNQVSVLHQVLYNQGQVDKVKPANKRAVTSDSKSDRQDSVNSQKAVRHETSSSEKVAPVLDADSILGPDSTAEDVSGMLPAVDKEISFIQCNTQSESLPKQVKLSCTEHPPTTCNVELSVPQIQKEPSSKIVPKKPQRHSLPTAGVLKKAASEELVEKNSYSSRKATNSEKGLERNHFQHLGPSSRGISSSSFDTPNSTSEKPVWKLPHPILPFSGSPESLKRVTLSLNNEPSISLTKPRAKSLSAVDMDRCNKPCKELPKKTSFKKLINVKLSIGFIKSDFQKFRSKSYQQADVTTGHLLSREPKKLESDWQGLVTGEEKRSKPIKAYSAENCSLESQKVKSWGQTSAANGQRAESLDDQLLSRDSSCQVSYKSSTSGCVPEYENVCHYEEIPEYENLPFVTAGGKTPELGWQNSSSAEDTDANLYEVEEPYDAPDGQLQLDPRHQPSSSGTPKEGQDDLNLGLGDLPSDEEVINSSDEDDVSSESSKGEPDPMEDKQGEDTGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLSWNEQQRIADIFVKKGPYLKMYSTYIKEFDKNIALLDEQCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLLEDSVDHRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLSGHHEIVQPGRVFLKEGILMKLSRKVMQPRMFFLFNDALLYTTPMQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSATERDDWLEAISRSIEEYAKKKITFCPSRSLDEDSEKKEEVSPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKRQLARVCEHCFQELQKLDHQLPPRIGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSTMSGYLYRSKGSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVTQVKDENSESKVFQLLHKGMVFYVFKADDAHSTQKWIEAFQEGTIL", "length": 1417, "header": "tr|A0A8C2MUN7-1|A0A8C2MUN7_CRIGR Isoform 1 of FYVE, RhoGEF and PH domain-containing protein 6 OS=Cricetulus griseus OX=10029 GN=Fgd6 PE=4 SV=1 CANONICAL=A0A8C2MUN7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUN7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUN7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUN7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUN7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756530", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756530", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K7L6-1", "protein_name": "FYVE, RhoGEF and PH domain containing 6", "gene_name": "Fgd6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "FFPLELKKPPLAPKPKLVGTNNKSPPPPIAPKPDIGNASVPRLTKTKPAIAPKPKVLTNSDVQDVKDQPSKKLTLNLEEREPELPESTGKFNCKDVGDAHGDYIFPTCSCSSGCTHEPRTRENLCAEQLVLEPLGMKEHLENGKNGESSKRGSRWNSSREKCRSQSGVVLKASIFEEKLKEVLTQPRSRSPSSSPRKHRCPNKPEMNGDHSCARQVRIEFADTSSSQSSFGKAPHSCHTQPPRDKSQNLQTCQDGSAESLGPFHSCELEGKRGCSGGTSQKSEVQGLGPVEIHLLPYTSKFPTPKPRRTHAARLRRQKHVDTPSESTEEPESSNNGSSCLHEDSLKNNKVSVLHQNALSNQGPVDEVRPGNKKALTRESNSDRQDSVSSQKAVQHETSSFEKVAPSLDTDSSLTSDSTVEDGSDVLPAVDRETAFIQCSPQPLSLPKQVKLACAEQQPTTCNREVSVPQIQKESSSRIVPKKPQRHSLPAAGVLKKAASEELVEKNSSSKETNSEKGLQRNHLQHLGPSNHGMSPSSFDMPNPTSEKPVWKLPHPILPFPGSPEALKRVTLSLNNEPSISLTKPRAKSLSAVDMDRCSKPCKEPPKKTTFKKLINVKLSIGFIKSDFHKFKSKNCQHGDVSTGHSLGREPKGLENNWQGLATGEEKKSKPIKAYSEENCSLESQKVKSWSQSSATNGQRAESLDDQMLSRHASCQASSTSDCGPEYENVRHYEEIPEYENLPFVMARGNPPELGWQNSSSVEDTDVSLYEVEEPYDAPDGQLQLDPRHQPCSSGRCQDRQDELHLDLPSDEEVINSSDEDDVSSESSKGEPDPLEDKQDEDAGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRGAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLSWAEQQRIADIFVKKGPYLKMYSMYIKEFDKNIALLDEQCKKNSGFATVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLLEDSVDHRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLSGHHEIVQPGRVFLKEGILMKLSRKVMQPRMIFLFNDALLYTTPMQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSASERDDWLEAISRAIEEYAKKRITFCPSRSLDEDSERKEEVSPLGAKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKCGLDYLKGQPARVCELCFQELQKLDHQLSPRIGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSTMSGYLYRSKGSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVAQVKDEHSDPRVFQLLHKGLLFYVFKADDAHSTQSTLPLSFQKGLVLFSQLWS", "length": 1412 }, "evidence": [ { "id": "A0A8C2MUN7", "url": "https://omabrowser.org/oma/group/A0A8C2MUN7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0YCC0-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 6", "gene_name": "FGD6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRSAGGQEGEEIKKPPVAPKPKFVVGHKATPPPVAPKPDVVLSGVLQAARKTKPAIAPKPKVLKSSSIPEVKPPSCARKGTKSFEEHRGDSSQTLDHLNYKNEVSEGSTDNTAYILPMSSCKFECLHKLGNGENTCKTQIILEHFENLENIKVDEKTALSLGSSPSEKMANRNQVVVKASILEEKLKDVLTHGVFPNRSPVRHRYADRLYKGDGNSSTNDVKIEFMELVQSSSSEVANGRQQNTGSKLTEDEFQTSETCPSLNENHSSFSCLLNQEILENENVNSSSSFSGEMGMKIDTGKTSSETCSALSSKMLPIPKPRKPRAACLVRQDGIDSVGEGTKEPSSSENDSFGPAEHSFKKPAKINVLGQSVCYNNHTEALNPEKSEITQSIADRMHLRKEPADTEESTLQNLLPQLSHKTSDLVENVECPLDTDHNLSSSVDRMTDDASMPDTVDKRTSFIRCDALSMSLPKQIKLPVSQHLPAANSLHVSLQKVEDREAKIKDESSPKIVPKKPQRHSLPAAGVLKKAASAELVEKSSYTSSEDKSNSVLEGSHFSHSPAREQGALSSSDIPRRSSEKPVWKLPHPILPFSGNSESLKTASIAPSFSHVSAVTKPRAKSLSSVDMERTDKPCKDTQKKNSLKKFLNVKLSVCLMKSDFQKLLSKGSQSMDSSTANLSTGEGYGNGNSRHVASVGSERKAKSAKARSVEISSPALQKKRQRNRSQPEMRSNQRLESLDGHSLPGENLSQMHLNSVTSNCAPEYENLRHYEEIPEYENLPFAMGAGKNLCLEWQNSSRVEDPSSSLYEVEEPFQAASRRVRHGRSLEEHHDHPGMVIGDLQSDDEDIVNSSDEDDDTNSDSSKGEPDSQDQSKAAGKKTKVYHIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLRELEERLSHWLEHQRIADIFVKKGPYLKMYSTYIKEFDKNIALLDEQCKKNAGFASVVKDFEMSPRCASLALKHYLLKPVQRIPQYRLLLTDYLKNLLEESADYRDTQDALAVVIEVANHANDIMKQGDNFQKLMQIQYSLNGHHEIVQPGRIFLKEGTLMKLSRKVMQPRMFFLFNDALLYTTPVQSGMYKLNNMLSLAGMKVKKPSQEAYQNELNIESVERSFILSASSATERDEWLEAISRSIEDYAKKRITFNPSKSLEEADTEKQEEASPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKHGLDYMKNQPARVCDHCFRELQKQDNQCSPKTGSPVNHKSPSSALSTVLHSIPSGRKQKKIPAALKEVSANTEDSTMSGYLHRSKGSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVSEVRDENSESRVFHLLHKNTLFYIFKADDPHSAQKWIEAFQEGTVL", "length": 1439 }, "evidence": [ { "id": "A0A8C2MUN7", "url": "https://omabrowser.org/oma/group/A0A8C2MUN7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MQ30-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 6", "gene_name": "FGD6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTSAAEIKKPPVAPKPKFVLAANKPAPPPVAPKPEILVSSVPQSTKKTKPSIAPKPKVLKASPVQDITQSPSRKIVVNLEEHTQEFPESIDNSNCRNRGHPSSDYILPVCSCHPGCNHKLESRKNLYVKQLVLGPLEMHENLENNKIGESPSAVKNQHKCDSVGERVKSQSKVVLKASILEEKLKDVLTQPMSPFLFPQKHRSTDSPEMSDGCNSHRQFSIEFADLSPSLSSFENVSNHHPCHLQLPSTEFQNFETNQNDSEKSNTCYHSSEQEALENGKRSPFLSSDGDSKKSEARDLGPLEIHLVPCTPKFPTPKPRKTHVARLLRQRHIDTSSESTEEPEDVDSLPHVFEDSLKNNKISVFHQTALCNQEQVDKVKPENKGELNVDLTGDRQNSVYSQKALRPETFSSEKTAPPLETDSNLSSDDKSGDSSGMSLAEDKGISFIRCSTLSMSLPKQLKLTCSEHLPTASNPGVSAPQMQKESMIKGESSSKVVPKKPQRHSLPAAGVLKKAASEELLEKSSYPSNEEKDAEKGLERDHVQHLCAPNNGMSSSFDMPKRASEKPVWKLPHPIIPFSGNPESLKSVTISSNSETPTPLTKPRAKSLSAMDVERCTKPCKDSHKKNSLKKLLNMKLSICFMKSDFQKFWSKHSHLGDTTSGSLAGGEQRGSESDWHGLLVGEEKRSKPIKAYSADNYSLESHKKRKKLRGHTNAANGPRAESLDDQMLSRESSLQAPCKSVTSDCVPEYENIRHYEEIPEYENLPFVMAMGKTPELERRNSSSVEDTDANVYEVQEPYEAPDGQLQLGPRHQHSSSSGASQEGQSDLDLGLGDLPSDEEEVINSSDEDDVSSASSKGEPDLLDDKQGEDTGMKCKVHHIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMSNWTEQQRIADIFVKKGPYLKMYSTYIKEFDKNIALLDEQCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLLEDSGDYRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLNGHHEIVQPGRVFLKEGILMKLSRKVMQPRMFFLFNDALLYTTPVQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSAPERDEWLEAISRSIEEYAKKRITFCPSRSLDEADSEDKDEVSPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPARVCEHCFQELQKLDHQHSPKFGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSSMSGYLYRSKGNKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVTQVKDENSESRVFQLLHKNMLFYVFKADDAHSAQKWIEAFQEGTIL", "length": 1434 }, "evidence": [ { "id": "A0A8C2MUN7", "url": "https://omabrowser.org/oma/group/A0A8C2MUN7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q69ZL1-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 6", "gene_name": "Fgd6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSAAELKKPPLAPKPKLVGTNNKPPPPPIAPKPDIGSASVPRLTKKTKPAIAPKPKVPTNSVVQDIKHPPSKKPTLNLEEREPELPESTGKSNCKDVRDPHSDYILPTCSCSSGCIHEPRTRETQCVEQLVLEPLGMKENLENSKNGESSKRGSSWDSSSEKCRGQSGVVLKASILEEKLKEVLTQQRSPCGSPGRHRAPKKPEMNGDHSCTRQIRIEFADVSSSLTGFEKVPAHHNCHPQLPRDESQTLKTCQDGSAESRGHTDSCEPENKRVASDGISQKTEVKGLGPLEIHLLPYTSKFPTPKPRKTHAAARLRRQKHVDTPGESTEEPGNSNNGSSCLLEDYCLKNNKVSVLRQNALYNQGPVDEVRPANQRALTGDSNSGGQDSVGSQKAVQQQTPSLDTDSSLTSDSSGSGVSPAVDKETTYTQCSTQPLSLPKQVTSACTDQPPATCNPEVSAPPIQKESSSSRIIPKKPQRHSLPAAGVLKKAASEELVEKSSSGKETNVEKGLHRNYLHHPGPPNHGASASPFDMPNPTSEKPVWKLPHPILPFSGSPEALKRVTLSLNNEPSVSLTKPRAKSLSAVDADRCNKPCKDPPKKTSFKKLINVKLSIGFIKSDFQKIRSKSCQHGDVSAGHPLAREPKGLESDWQGLATGEEKRSKPTKAHSAENCSLESQKVKSWGQSSAVNGQRAESLDDRILSRHTSCTGDFGPEYENVRHYEEIPEYENLPFVMAGRNTPDLGWQNSSSVEDTDASLYEVEEPYNAPDGQLQLDPRHQPCSSGTSQEGKDALHLGLSDLPSDEEVINSSDEDDVSSESSKGEPDPLEDKQDEDAGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRGAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLTWTEQQRIADIFVKKGPYLKMYSTYIKEFDKNVALLDEQCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLLEDSVDHRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLSGHHEIVQPGRVFLKEGTLMKLSRKVMQPRMFFLFNDALLYTTPMQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSAAERDDWLEAISSSIEEYAKKRITFCPSRSLDEDSERKEEVSPLGAKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKGQLARVCEHCFQELQKLDHQLSPRVGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSTMSGYLYRSKGSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVTLVKDENSESKVFQLLHKGMVFYVFKADDAHSTQRWIDAFQEGTVL", "length": 1399 }, "evidence": [ { "id": "A0A8C2MUN7", "url": "https://omabrowser.org/oma/group/A0A8C2MUN7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZV73-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 6", "gene_name": "FGD6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MUU4-1", "uniprot_ac": "A0A8C2MUU4", "uniprot_id": "A0A8C2MUU4_CRIGR", "mass": { "chemical_mass": 67545.0, "monoisotopic_mass": 67545.0 }, "refseq": { "ac": "XP_027255550", "name": "transmembrane 9 superfamily member 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255550" }, "gene_names": [ { "name": "Tm9sf3", "type": "recommended", "evidence": [ { "id": "A0A8C2MUU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUU4" } ] }, { "name": "Tm9sf3", "type": "synonym", "evidence": [ { "id": "XP_027255550", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255550" } ] } ], "protein_names": [ { "name": "Transmembrane 9 superfamily member", "type": "recommended", "evidence": [ { "id": "A0A8C2MUU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUU4/entry#names_and_taxonomy" } ] }, { "name": "transmembrane 9 superfamily member 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027255550", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255550" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 259 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613664.1) and transcript sequence (IACG01052702.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027255550.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027255550", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255550" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUU4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUU4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tm9sf3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUU4", "locus": {} } ], "crossref": [ { "id": "100764030", "url": "https://www.ncbi.nlm.nih.gov/gene/100764030", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764030", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764030", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MUU4", "url": "https://www.orthodb.org/?gene=A0A8C2MUU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10766", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10766", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10766:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10766:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02990", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02990", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027255550", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255550", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MUU4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPLPGAPGVAAAAALLLLLLPRARSDEHEHTYQDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFKDDVMPGTYCEIDLDKEKRDAFVYAIKNHYWYQMYIDDLPIWGIVGEADENGEDYYLWTYKKLEIGFNGNRIVDVNLTSEGKVKLVPNTKIQMSYSVKWKKSDVKFEDRFDKYLDPSFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDLGDEYGWKQVHGDVFRPSSHPLIFSSLIGSGCQIFAVSLIVIIVAMIEDLYTERGSMLSTAIFVYAATSPVNGYFGGSLYARQGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILGRNLSGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID", "length": 587, "header": "tr|A0A8C2MUU4-1|A0A8C2MUU4_CRIGR Isoform 1 of Transmembrane 9 superfamily member OS=Cricetulus griseus OX=10029 GN=Tm9sf3 PE=3 SV=1 CANONICAL=A0A8C2MUU4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MUU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUU4/entry#A0A8C2MUU4-1", "sequence": { "sequence": "MRPLPGAPGVAAAAALLLLLLPRARSDEHEHTYQDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFKDDVMPGTYCEIDLDKEKRDAFVYAIKNHYWYQMYIDDLPIWGIVGEADENGEDYYLWTYKKLEIGFNGNRIVDVNLTSEGKVKLVPNTKIQMSYSVKWKKSDVKFEDRFDKYLDPSFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDLGDEYGWKQVHGDVFRPSSHPLIFSSLIGSGCQIFAVSLIVIIVAMIEDLYTERGSMLSTAIFVYAATSPVNGYFGGSLYARQGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILGRNLSGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID", "length": 587, "header": "tr|A0A8C2MUU4-1|A0A8C2MUU4_CRIGR Isoform 1 of Transmembrane 9 superfamily member OS=Cricetulus griseus OX=10029 GN=Tm9sf3 PE=3 SV=1 CANONICAL=A0A8C2MUU4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUU4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUU4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279576" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVK9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVK9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Stxbp1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVK9", "locus": {} } ], "crossref": [ { "id": "100761087", "url": "https://www.ncbi.nlm.nih.gov/gene/100761087", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001619", "database": "InterPro", "categories": [ "Protein Classification" ] 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00995", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00995", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279576", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MUZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MVK9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MVK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUZ1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MUZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUZ1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761087", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761087", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of regulated secretory pathway", "id": "GO:1903307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903307", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVK9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVK9" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": 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This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027287746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287746" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MV02", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV02" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Wdr44", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV02", "locus": {} } ], "crossref": [ { "id": "100764342", "url": "https://www.ncbi.nlm.nih.gov/gene/100764342", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] 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repeat-containing protein 44 OS=Cricetulus griseus OX=10029 GN=Wdr44 PE=4 SV=1 CANONICAL=A0A8C2MV02-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KA02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV02/entry#A0A9J7KA02-1", "sequence": { "sequence": 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}, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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CANONICAL=A0A8C2MVB0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MVB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVB0/entry#A0A8C2MVB0-1", "sequence": { "sequence": "MRLSPAPLRLSRGPALLALALPLAVALAFSDETLDKVSKSEGYCSRILRAQGTRREGYTEFSLRVEGDPEFYKPGSSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPTGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDPSLDGVTDRPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPVNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPRSCLVTEWGEWDDCSATCGMGMKKRHRMIKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCELSEWSQWSECNKSCGKGHMIRTRTIQMEPQFGGVPCPETVQRKKCRARKCLRNPSVQKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC", "length": 807, 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"url": "https://www.uniprot.org/uniprotkb/A0A8C2MVB0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVB0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVB0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVB0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVB0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVB0" }, { "id": "PS51019", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51019" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reelin", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 194, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVB0" }, { "id": "PS51020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Spondin", "eco_id": "ECO_0000259", "start_pos": 195, "end_pos": 388, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 447, "end_pos": 449 }, { "start_pos": 681, "end_pos": 683 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MVD4-1", "uniprot_ac": "A0A8C2MVD4", "uniprot_id": "A0A8C2MVD4_CRIGR", "mass": { "chemical_mass": 55258.0, "monoisotopic_mass": 55258.0 }, "refseq": { "ac": "XP_007645430", "name": "chromobox protein homolog 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645430" }, "gene_names": [ { "name": "Cbx2", "type": "recommended", "evidence": [ { "id": "A0A8C2MVD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVD4" } ] }, { "name": "Cbx2", "type": "synonym", "evidence": [ { "id": "XP_007645430", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645430" } ] } ], "protein_names": [ { "name": "Chromobox protein homolog 2 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2MVD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVD4/entry#names_and_taxonomy" } ] }, { "name": "chromobox protein homolog 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007645430", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645430" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 178 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614274.1) and transcript sequence (IACG01083033.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007645430.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007645430", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645430" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVD4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVD4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cbx2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVD4", "locus": {} } ], "crossref": [ { "id": "cd18647", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18647", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755979", "url": "https://www.ncbi.nlm.nih.gov/gene/100755979", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755979", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755979", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MVD4", "url": "https://www.orthodb.org/?gene=A0A8C2MVD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46860:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46860:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17218", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17218", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007645430", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645430", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MVD4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MVD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKHTVMSSCSRRSKLKEPDAPSKSKSSSSSSSSSSSSSSSDEEEDDSDLDSKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKAARRPVSLAKVLKTTRKDLGTSASKLPPPLSAPVAGLAALKAHTKEACSGSSAMATPENLASLMKGMAGSPNRGGISWQSSIVHYMNRMSQSQAQTASRLALKAQAANKCSLGLDLKVRTQKGDLGVSPPGSKALKAPGGAAAEQQKGSSSGGPGSQLAPTQELSLQVLDLQSVKNGMPGMGLLSRHATATKAIPATNPATGKGPGGSPTGINMTSTPTDTSKGEKMASKATALPTPSVKRDSVKCMAASSGQEGHTVPGEGRKAPALSEMSTGEENSSSDTDPDSSSLPSAGQNLSVSVQTNQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRHY", "length": 520, "header": "tr|A0A8C2MVD4-1|A0A8C2MVD4_CRIGR Isoform 1 of Chromobox protein homolog 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Cbx2 PE=4 SV=1 CANONICAL=A0A8C2MVD4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MVD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVD4/entry#A0A8C2MVD4-1", "sequence": { "sequence": "MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKHTVMSSCSRRSKLKEPDAPSKSKSSSSSSSSSSSSSSSDEEEDDSDLDSKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKAARRPVSLAKVLKTTRKDLGTSASKLPPPLSAPVAGLAALKAHTKEACSGSSAMATPENLASLMKGMAGSPNRGGISWQSSIVHYMNRMSQSQAQTASRLALKAQAANKCSLGLDLKVRTQKGDLGVSPPGSKALKAPGGAAAEQQKGSSSGGPGSQLAPTQELSLQVLDLQSVKNGMPGMGLLSRHATATKAIPATNPATGKGPGGSPTGINMTSTPTDTSKGEKMASKATALPTPSVKRDSVKCMAASSGQEGHTVPGEGRKAPALSEMSTGEENSSSDTDPDSSSLPSAGQNLSVSVQTNQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRHY", "length": 520, "header": "tr|A0A8C2MVD4-1|A0A8C2MVD4_CRIGR Isoform 1 of Chromobox protein homolog 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Cbx2 PE=4 SV=1 CANONICAL=A0A8C2MVD4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027247626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247626" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cpb1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR0", "locus": {} } ], "crossref": [ { "id": "cd03871", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03871", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751091", "url": "https://www.ncbi.nlm.nih.gov/gene/100751091", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751091", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751091", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MVR0", "url": "https://www.orthodb.org/?gene=A0A8C2MVR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11705:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11705:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027247626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247626", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MVR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLLLALVSVALAHPFEEDFDGNRVFRVSVPDEDHVNLIQELANTKQIDFWKPDSAVQVKPLTSVDFHVKAEDVATVEDFLEKNEFHYEVLISNVKNLVEAQFDSHTRATGHSYTKYNNWEKIEAWIQQIASENPQLISQSTIGTTFEGRNIYLLKVGKAKPNKPAIFIDCGFHAREWISPAFCQWFVKEAVRTYEQEIHMKQLLDELDFYVLPVVNIDGYVYTWTKSRMWRKTRSTRAGSSCVGVDPNRNFNAGWCEVGASRSPCSDTYCGPAAESEKETKALADFIRKNLSSIKAYLTIHSYSQLLLYPYSYANKLPANYEELNALVKGAVKELASLHGTKYTYGPGASTIYLAAGGSDDWAYDQGIKYSFTFELRDTGTFGFLLPESQIRYTCEETMLAVKYIANYVREHLY", "length": 415, "header": "tr|A0A8C2MVR0-1|A0A8C2MVR0_CRIGR Isoform 1 of Carboxypeptidase B OS=Cricetulus griseus OX=10029 GN=Cpb1 PE=3 SV=1 CANONICAL=A0A8C2MVR0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MVR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR0/entry#A0A8C2MVR0-1", "sequence": { "sequence": "MLLLLALVSVALAHPFEEDFDGNRVFRVSVPDEDHVNLIQELANTKQIDFWKPDSAVQVKPLTSVDFHVKAEDVATVEDFLEKNEFHYEVLISNVKNLVEAQFDSHTRATGHSYTKYNNWEKIEAWIQQIASENPQLISQSTIGTTFEGRNIYLLKVGKAKPNKPAIFIDCGFHAREWISPAFCQWFVKEAVRTYEQEIHMKQLLDELDFYVLPVVNIDGYVYTWTKSRMWRKTRSTRAGSSCVGVDPNRNFNAGWCEVGASRSPCSDTYCGPAAESEKETKALADFIRKNLSSIKAYLTIHSYSQLLLYPYSYANKLPANYEELNALVKGAVKELASLHGTKYTYGPGASTIYLAAGGSDDWAYDQGIKYSFTFELRDTGTFGFLLPESQIRYTCEETMLAVKYIANYVREHLY", "length": 415, "header": "tr|A0A8C2MVR0-1|A0A8C2MVR0_CRIGR Isoform 1 of Carboxypeptidase B OS=Cricetulus griseus OX=10029 GN=Cpb1 PE=3 SV=1 CANONICAL=A0A8C2MVR0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751091", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751091", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR0" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR0" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR0" }, { "id": "PS52035", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M14", "eco_id": "ECO_0000259", "start_pos": 116, "end_pos": 410, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.17.2", "ec_name": "Preferential release of a C-terminal lysine or arginine amino acid.", "evidence": [ { "id": "3.4.17.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.17.2" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 291, "end_pos": 293 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MVR2-1", "uniprot_ac": "A0A8C2MVR2", "uniprot_id": "A0A8C2MVR2_CRIGR", "mass": { "chemical_mass": 73483.0, "monoisotopic_mass": 73483.0 }, "refseq": { "ac": "XP_027283026", "name": "A-kinase anchor protein 10, mitochondrial isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283026" }, "gene_names": [ { "name": "Akap10", "type": "recommended", "evidence": [ { "id": "A0A8C2MVR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2" } ] }, { "name": "Akap10", "type": "synonym", "evidence": [ { "id": "XP_027283026", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283026" } ] } ], "protein_names": [ { "name": "A-kinase anchor protein 10, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8C2MVR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2/entry#names_and_taxonomy" } ] }, { "name": "A-kinase anchor protein 10, mitochondrial isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027283026", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283026" } ] }, { "name": "Dual specificity A kinase-anchoring protein 2", "type": "synonym", "evidence": [ { "id": "A0A8C2MVR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2/entry#names_and_taxonomy" } ] }, { "name": "Protein kinase A-anchoring protein 10", "type": "synonym", "evidence": [ { "id": "A0A8C2MVR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283026", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283026" } ] }, { "annotation": "Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2#function" }, { "database": "UniProtKB", "id": "ARBA00055118", "url": "https://www.uniprot.org/uniprotkb/ARBA00055118#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Akap10", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2", "locus": {} } ], "crossref": [ { "id": "cd08721", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08721", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08735", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08735", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12804", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12804", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759380", "url": "https://www.ncbi.nlm.nih.gov/gene/100759380", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759380", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759380", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MVR2", "url": "https://www.orthodb.org/?gene=A0A8C2MVR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13155", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13155", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13155:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13155:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027283026", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283026", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MVR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MVR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGAGPSPRQSPRALRPDPGPAMSFFRRKVKGKEQEKTSDVKSIKASVAVHSPQKSTKNHALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKSSLSKTLEQVLRDAAVLPYFLQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKKQETTVTSITESLDRRLGDSSSAPLLMTQPEGIDLSSRTQNTQNHLLLSQECHSAHSLHLATARTGTHPISTDSPESSSRLTVASSDSPSSPLRDLSGKLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIAKICGEDGQVDPNCFVLAQAVVFSAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHSVRGDEFLGGNISLAAHGSVCLPEESHSGGSDGSTAQSNVKKASIKILKNFDEAIIVDAASLDPESLYQRTYAGKMSFGRVSDLGQFIRESEPEPDVKKSKGFMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDVMQQAHYDQPLEKSTKL", "length": 662, "header": "tr|A0A8C2MVR2-1|A0A8C2MVR2_CRIGR Isoform 1 of A-kinase anchor protein 10, mitochondrial OS=Cricetulus griseus OX=10029 GN=Akap10 PE=4 SV=1 CANONICAL=A0A8C2MVR2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MVR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2/entry#A0A8C2MVR2-1", "sequence": { "sequence": "MRGAGPSPRQSPRALRPDPGPAMSFFRRKVKGKEQEKTSDVKSIKASVAVHSPQKSTKNHALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKSSLSKTLEQVLRDAAVLPYFLQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKKQETTVTSITESLDRRLGDSSSAPLLMTQPEGIDLSSRTQNTQNHLLLSQECHSAHSLHLATARTGTHPISTDSPESSSRLTVASSDSPSSPLRDLSGKLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIAKICGEDGQVDPNCFVLAQAVVFSAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHSVRGDEFLGGNISLAAHGSVCLPEESHSGGSDGSTAQSNVKKASIKILKNFDEAIIVDAASLDPESLYQRTYAGKMSFGRVSDLGQFIRESEPEPDVKKSKGFMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDVMQQAHYDQPLEKSTKL", "length": 662, "header": "tr|A0A8C2MVR2-1|A0A8C2MVR2_CRIGR Isoform 1 of A-kinase anchor protein 10, mitochondrial OS=Cricetulus griseus OX=10029 GN=Akap10 PE=4 SV=1 CANONICAL=A0A8C2MVR2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759380", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759380", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase A binding", "id": "GO:0051018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051018", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MVR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVR2" }, { "id": "PS50132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RGS", "eco_id": "ECO_0000259", "start_pos": 125, "end_pos": 369, "start_aa": "Thr", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 521, "end_pos": 523 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MVT2-1", "uniprot_ac": "A0A8C2MVT2", "uniprot_id": "A0A8C2MVT2_CRIGR", "mass": { "chemical_mass": 269736.0, "monoisotopic_mass": 269736.0 }, "refseq": { "ac": "XP_027259031", "name": "talin-1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259031" }, "gene_names": [ { "name": "Tln1", "type": "recommended", "evidence": [ { "id": "A0A8C2MVT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2" } ] }, { "name": "Tln1", "type": "synonym", "evidence": [ { "id": "XP_027259031", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259031" } ] } ], "protein_names": [ { "name": "Talin-1 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2MVT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2/entry#names_and_taxonomy" } ] }, { "name": "talin-1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027259031", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259031" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027259031", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259031" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tln1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2", "locus": {} } ], "crossref": [ { "id": "cd10569", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10569", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12150", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12150", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17171", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17171", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17173", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17173", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755764", "url": "https://www.ncbi.nlm.nih.gov/gene/100755764", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002558", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002558", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019747", "database": "InterPro", "categories": [ "Protein 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755764", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755764", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MVT2", "url": "https://www.orthodb.org/?gene=A0A8C2MVT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19981", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19981", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19981:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19981:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01608", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02174", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02174", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08913", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08913", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09379", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09379", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16511", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16511", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21692", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21692", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21865", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21865", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21896", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21896", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027259031", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259031", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MVT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MVT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 2541, "header": "tr|A0A8C2MVT2-1|A0A8C2MVT2_CRIGR Isoform 1 of Talin-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tln1 PE=4 SV=1 CANONICAL=A0A8C2MVT2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MVT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2/entry#A0A8C2MVT2-1", "sequence": { "sequence": "MVALSLKISIGNVVKTMQFEPSTMVYDACRMIRERIPEALAGPPSDFGLFLSDDDPKKGIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTVMVDDSKTVTDMLMTICARIGITNHDEYSLVRELMEEKKDEGTGTLRKDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVKQKGERKIFQAHKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWSLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEHGSVALPAIMRSGASGPENFQMGSMPPAQQQITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAAQATLDDFDTLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLEDEGGNGRPLLQAAKGLAGAVSELLRSAQPASTEPRQNLLQAAGNVGQASGELLQQIGESDTDPHFQDVLMQLAKAVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAGPAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGESDLENSRKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMATNAAAQNAIKKKLVQRLEHAAKQAAASATQTIAAAQHAASAPKASAGPQPLLVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTIQDQASAMQLSQCAKNLGTALAELRTAAQKAQEACGPLEMDSALSVVQNLEKDLQEVKAAARDGKLKPLPGETMEKCAQDLGNSTKAVSSAIAKLLGEVAQGNENYAGIAARDVAGGLRSLAQAARGVAALTSDPAVQAIVLDTASDVLDKASSLIDEAKKAAGHPGDPESQQRLAQVAKAVTQALNRCVSCLPGQRDVDNALRAVGDASKRLLSDSLPPSTGTFQEAQSRLNEAAAGLNQAATELVQASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISMSSSKLLLAAKALSTDPAAPNLKSQLAAAARAVTDSINQLITMCTQQAPGQKECDNALRELETVRELLENPVQPINDMSYFGCLDSVMENSKVLGEAMTGISQNAKNGNLPEFGDAIATASKALCGFTEAAAQAAYLVGVSDPNSQAGQQGLVEPTQFARANQAIQMACQSLGEPGCTQAQVLSAATIVAKHTSALCNSCRLASARTANPTAKRQFVQSAKEVANSTANLVKTIKALDGAFTEENRAQCRAATAPLLEAVDNLSAFASNPEFSSIPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPRWSVLAGHSRTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLATAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDEGPMGEPDGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYGRLASQAKPAAVAAENEEIGAHIKHRVQELGHGCSALVTKAGALQCNPSDVYTKKELIECARRVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMFATAGTLNREGAESFADHREGILKTAKVLVEDTKVLVQNAAGSQEKLAQAAQSSVATITRLADVVKLGAASLGAEDPETQVVLINAVKDVAKALGDLISATKAAAGKVGDDPAVWQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATTEHIRQELAVFCSPEPPAKTSTPEDFIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRRAIADMLRACKEAAFHPEVAPDVRLRALHYGRECANGYLELLDHVLLTLQKPNPELKQQLTGHSKRVAGSVTELIQAAEAMKGTEWVDPEDPTVIAENELLGAAAAIEAAAKKLEQLKPRAKPKEADESLNFEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANALDDGQWSQGLISAARMVAAATNNLCEAANAAVQGHASQEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAGNAVKRASDNLVKAAQKAAAFEDQENETVVVKEKMVGGIAQIIAAQEEMLRKERELEEARKKLAQIRQQQYKFLPSELRDEH", "length": 2541, "header": "tr|A0A8C2MVT2-1|A0A8C2MVT2_CRIGR Isoform 1 of Talin-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tln1 PE=4 SV=1 CANONICAL=A0A8C2MVT2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755764", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755764", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2" } ], "pmid": "" }, { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell junction assembly", "id": "GO:0034329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034329", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVT2" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": 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"sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027259209", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259209" } ] }, { "annotation": "Catalyzes the attachment of arginine to tRNA(Arg) in a two-step reaction: arginine is first activated by ATP to form Arg-AMP and then transferred to the acceptor end of tRNA(Arg).", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVU1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVU1#function" }, { "database": "UniProtKB", "id": "ARBA00049595", "url": "https://www.uniprot.org/uniprotkb/ARBA00049595#function" }, { "database": "UniProtKB", "id": "A0A9J7GQP2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQP2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVU1", "url": 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"Protein" ] }, { "id": "A0A8C2MVU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GQP2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GQP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MACVFRRSIACQLSQVLALPPESLIKSISAVPVSKKEEVADFQLSVDSLLEDNNQKSQLDTQDQARRLAEKLKCDTVVTAISAGPKTLNFKINRELLTKAVLQQVTEDGSKYGLKSELFSGLPQKRIVVEFSSPNVAKKFHVGHLRSTIIGNFIANLKEALGHRVTRINYIGDWGMQFGLLGTGFQLFGYEEKLQSNPLQHLFEVYVQVNKEATDDKNIAKLAHEFFHRLELGDTQALSLWQRFRDLSIEEYIQIYKRLGIHFDEYSGESFYREKSRDVVKLLDSKGLLQKTVTGNVVVDLSETGDLSSICTVKRSDGTSLYATRDLAAAIDRMNKYNFDTMIYVADKGQKRHFQQVFQILKIMGYEWAERCQHVAFGIVKGMKTRRGDVTFLEDVLNEVQSRMLQNMASIKTTKKMENPQETAERVGLAALIIQDFKGLLLSDYQFSWDRVLQNRGDTGVFLQYTHARLYSLEETFGCGYLNDVNVACLQEPQSVSILQHLLRFDEVLYKSSQDLQPKHIVSYLLTLSHLAAIAHKTLQVKDSPADVAGARLHLFRAVRSVLANGMKLLGITPVYRM", "length": 578, "header": "tr|A0A8C2MVU1-1|A0A8C2MVU1_CRIGR Isoform 1 of Probable arginine--tRNA ligase, mitochondrial OS=Cricetulus griseus OX=10029 GN=Rars2 PE=3 SV=1 CANONICAL=A0A8C2MVU1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MVU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVU1/entry#A0A8C2MVU1-1", "sequence": { "sequence": "MACVFRRSIACQLSQVLALPPESLIKSISAVPVSKKEEVADFQLSVDSLLEDNNQKSQLDTQDQARRLAEKLKCDTVVTAISAGPKTLNFKINRELLTKAVLQQVTEDGSKYGLKSELFSGLPQKRIVVEFSSPNVAKKFHVGHLRSTIIGNFIANLKEALGHRVTRINYIGDWGMQFGLLGTGFQLFGYEEKLQSNPLQHLFEVYVQVNKEATDDKNIAKLAHEFFHRLELGDTQALSLWQRFRDLSIEEYIQIYKRLGIHFDEYSGESFYREKSRDVVKLLDSKGLLQKTVTGNVVVDLSETGDLSSICTVKRSDGTSLYATRDLAAAIDRMNKYNFDTMIYVADKGQKRHFQQVFQILKIMGYEWAERCQHVAFGIVKGMKTRRGDVTFLEDVLNEVQSRMLQNMASIKTTKKMENPQETAERVGLAALIIQDFKGLLLSDYQFSWDRVLQNRGDTGVFLQYTHARLYSLEETFGCGYLNDVNVACLQEPQSVSILQHLLRFDEVLYKSSQDLQPKHIVSYLLTLSHLAAIAHKTLQVKDSPADVAGARLHLFRAVRSVLANGMKLLGITPVYRM", "length": 578, "header": "tr|A0A8C2MVU1-1|A0A8C2MVU1_CRIGR Isoform 1 of Probable arginine--tRNA ligase, mitochondrial OS=Cricetulus griseus OX=10029 GN=Rars2 PE=3 SV=1 CANONICAL=A0A8C2MVU1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GQP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVU1/entry#A0A9J7GQP2-1", "sequence": { "sequence": "MQFGLLGTGFQLFGYEEKLQSNPLQHLFEVYVQVNKEATDDKNIAKLAHEFFHRLELGDTQALSLWQRFRDLSIEEYIQIYKRLGIHFDEYSGESFYREKSRDVVKLLDSKGLLQKTVTGNVVVDLSETGDLSSICTVKRSDGTSLYATRDLAAAIDRMNKYNFDTMIYVADKGQKRHFQQVFQILKIMGYEWAERCQHVAFGIVKGMKTRRGDVTFLEDVLNEVQSRMLQNMASIKTTKKMENPQETAERVGLAALIIQDFKGLLLSDYQFSWDRVLQNRGDTGVFLQYTHARLYSLEETFGCGYLNDVNVACLQEPQSVSILQHLLRFDEVLYKSSQDLQPKHIVSYLLTLSHLAAIAHKTLQVKDSPADVAGARLHLFRAVRSVLANGMKLLGITPVYRM", "length": 403, "header": "tr|A0A9J7GQP2-1|A0A9J7GQP2_CRIGR Computationally mapped isoform of Probable arginine--tRNA ligase, mitochondrial OS=Cricetulus griseus OX=10029 GN=Rars2 PE=3 SV=1 CANONICAL=A0A8C2MVU1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVU1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVU1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVU1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVU1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768428", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768428", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVU1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVU1" } ], "pmid": "" }, { "name": "arginine-tRNA ligase activity", "id": "GO:0004814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004814", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVU1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVU1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVU1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVU1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVU1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVU1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "arginyl-tRNA aminoacylation", "id": "GO:0006420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006420", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVU1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVU1" } ], "pmid": "" }, { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVU1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVU1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20301", "name": "", "equation": "tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P37880-1", "A0A9J7GAS9-1", "A0A8C2MVU1-1" ], "evidence": [ { "id": "20301", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20301" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8C2MVU1", "gene_name": "Rars2", "activity": [ { "ec_number": "6.1.1.19", "activity": "tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate.", "evidence": [ { "id": "A0A8C2MVU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVU1" } ] }, { "ec_number": "6.1.1.19", "activity": "", "evidence": [ { "id": "A0A8C2MVU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVU1" } ] } ] }, { "uniprot_ac": "A0A9J7GAS9", "gene_name": "Rars1", "activity": [ { "ec_number": "6.1.1.19", "activity": "tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate.", "evidence": [ { "id": "A0A9J7GAS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAS9" } ] }, { "ec_number": "6.1.1.19", "activity": "", "evidence": [ { "id": "A0A9J7GAS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAS9" } ] } ] }, { "uniprot_ac": "P37880", "gene_name": "RARS1", "activity": [ { "ec_number": "6.1.1.19", "activity": "tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate.", "evidence": [ { "id": "P37880", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37880" } ] }, { "ec_number": "6.1.1.19", "activity": "", "evidence": [ { "id": "P37880", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37880" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MVU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVU1" }, { "id": "SM00836", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00836" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DALR anticodon binding", "eco_id": "ECO_0000259", "start_pos": 463, "end_pos": 578, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "6.1.1.19", "ec_name": "tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate.", "evidence": [ { "id": "6.1.1.19", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.19" }, { "id": "6.1.1.19", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=6.1.1.19" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MVV4-1", "uniprot_ac": "A0A8C2MVV4", "uniprot_id": "A0A8C2MVV4_CRIGR", "mass": { "chemical_mass": 47952.0, "monoisotopic_mass": 47952.0 }, "refseq": { "ac": "XP_003510509", "name": "transmembrane protease serine 11E", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510509" }, "gene_names": [ { "name": "LOC100764592", "type": "recommended", "evidence": [ { "id": "A0A8C2MVV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4" } ] }, { "name": "LOC100764592", "type": "synonym", "evidence": [ { "id": "XP_003510509", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510509" } ] } ], "protein_names": [ { "name": "Transmembrane protease serine", "type": "recommended", "evidence": [ { "id": "A0A8C2MVV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4/entry#names_and_taxonomy" } ] }, { "name": "3.4.21.-", "type": "synonym", "evidence": [ { "id": "A0A8C2MVV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protease serine 11E", "type": "synonym", "evidence": [ { "id": "XP_003510509", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510509" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614886.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510509" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVV4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100764592", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4", "locus": {} } ], "crossref": [ { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764592", "url": "https://www.ncbi.nlm.nih.gov/gene/100764592", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764592", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764592", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HCFRTYK", "url": "https://omabrowser.org/oma/group/HCFRTYK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MVV4", "url": "https://www.orthodb.org/?gene=A0A8C2MVV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510509", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MVV4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MVV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYRPPVARARKRTCVEPWVIGLISFLSLIVVAVCIGLTVHYVRYNQRRTYNYYTTLPFTSDKLYSEFGREASKNFTEMSQRIETMVKNAFYKSPLRGQLVKAHIIKFSKEYDGVSAHMLLIFRIRYTEDPESVHQIVEYVLREKLKHAAGPPNVDPESVEIKKINKTETDNYLNHCCGTRRNKSTAQTSLRIVGGTQVEEGEWPWQSSLQWDGSHRCGAALINNTWLVSAAHCFRTHKDPSRWTASFGATIQPPKLRTGLRRIIVHEKYKYPSHDYDIALAELSRPVPCTNAVHKVCLPDANHEFHPGQKMFVTGFGALQNDGFTQNHLRQVQVDYIDTQTCNQPQSYNGAITPRMLCAGFLKGEKDACQGDSGGPLVASDVRDIWYLAGIVSWGDECGQPNKPGVYTRVTAFRDWIASKTGI", "length": 423, "header": "tr|A0A8C2MVV4-1|A0A8C2MVV4_CRIGR Isoform 1 of Transmembrane protease serine OS=Cricetulus griseus OX=10029 GN=LOC100764592 PE=3 SV=1 CANONICAL=A0A8C2MVV4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MVV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4/entry#A0A8C2MVV4-1", "sequence": { "sequence": "MYRPPVARARKRTCVEPWVIGLISFLSLIVVAVCIGLTVHYVRYNQRRTYNYYTTLPFTSDKLYSEFGREASKNFTEMSQRIETMVKNAFYKSPLRGQLVKAHIIKFSKEYDGVSAHMLLIFRIRYTEDPESVHQIVEYVLREKLKHAAGPPNVDPESVEIKKINKTETDNYLNHCCGTRRNKSTAQTSLRIVGGTQVEEGEWPWQSSLQWDGSHRCGAALINNTWLVSAAHCFRTHKDPSRWTASFGATIQPPKLRTGLRRIIVHEKYKYPSHDYDIALAELSRPVPCTNAVHKVCLPDANHEFHPGQKMFVTGFGALQNDGFTQNHLRQVQVDYIDTQTCNQPQSYNGAITPRMLCAGFLKGEKDACQGDSGGPLVASDVRDIWYLAGIVSWGDECGQPNKPGVYTRVTAFRDWIASKTGI", "length": 423, "header": "tr|A0A8C2MVV4-1|A0A8C2MVV4_CRIGR Isoform 1 of Transmembrane protease serine OS=Cricetulus griseus OX=10029 GN=LOC100764592 PE=3 SV=1 CANONICAL=A0A8C2MVV4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVV4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVV4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764592", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764592", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M2C4-1", "protein_name": "Transmembrane protease serine", "gene_name": "Tmprss11e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYRSPVVRARKRTYVEPWVIGLISFLSLIVLAVCIGLTVHYVRYNHRRTYNYYSTLPFTSDKLYSEFGKEASKNFTEMSQRIETMVKNAFHKSPLRGQLSKAHIIKFSKEDDGVLAHMLLIFRIRSTEDPEVVHKIIEYVLREKLKYATGPPKVDPESVEIKKINKTESDNYLNHCCGTRRNKSTAQTSVRIVGGTSAEEGEWPWQSSLQWDGSHRCGATLISNTWLVSAAHCFRTHKDPSRWTASFGATLQPPKLTTGIRRIIVHEKYNYPSHDYDIALVELSRPVPCTNAVHKVCLPDANHEFQPGQRMFVTGFGALRNDGFAQNYLRQVQVDYIDTQTCNRPQSYNGAITPRMLCAGFLKGEKDACQGDSGGPLVTPDVRDVWYLAGVVSWGDECGQPNKPGVYTRVTAFRDWITSNTGI", "length": 423 }, "evidence": [ { "id": "A0A8C2MVV4", "url": "https://omabrowser.org/oma/group/A0A8C2MVV4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5S248-1", "protein_name": "Transmembrane protease serine 11E", "gene_name": "Tmprss11e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYRSCVVRARKRTCVEPWVIGIISFLSLIVLAVCIGLTVHYVRYNHRRTYNYYSTLSFTSDKLYSEFGREASKNFTEMSQRIETMVKHAFHKSPLRGQLVKAHIIKFSKEDDGVLAHMLLIFRIRSTEDPETVHKIIEYVLHEKLKYATGPPNVDPESVKIKKINKTESDNYFNHCCGTRRNKSTVQTSVRIVGGTPVEEEEWPWQSSLRWDGSHRCGATLINNTWLVTAAHCFRTHKDPSRWSATFGATLQPRKLTTGIRRIIVHEKYKYPSHDYDIALAELSKPVPCTNAVHKVCLPDANHEFQPGQRMFVTGFGALKNDGFTQNNLRQVQVDYIDTQTCNQPQSYNGAITPRMLCAGFLKGEKDACQGDSGGPLVTADVRDIWYLAGVVSWGDECGQPNKPGVYTRVTAFRHWIASNTGI", "length": 423 }, "evidence": [ { "id": "A0A8C2MVV4", "url": "https://omabrowser.org/oma/group/A0A8C2MVV4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UL52-1", "protein_name": "Transmembrane protease serine 11E", "gene_name": "TMPRSS11E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMYRPDVVRARKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFTTDKLYAEFGREASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHMLLICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETDSYLNHCCGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKTGI", "length": 423 }, "evidence": [ { "id": "A0A8C2MVV4", "url": "https://omabrowser.org/oma/group/A0A8C2MVV4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVV4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVV4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVV4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVV4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4" } ], "pmid": "" }, { "name": "cognition", "id": "GO:0050890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050890", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVV4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MVV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 192, "end_pos": 422, "start_aa": "Ile", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MVV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVV4" }, { "id": "PS50024", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50024" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SEA", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 166, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 182, "end_pos": 184 }, { "start_pos": 223, "end_pos": 225 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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] }, { "uniprot_canonical_ac": "A0A8C2MVW3-1", "uniprot_ac": "A0A8C2MVW3", "uniprot_id": "A0A8C2MVW3_CRIGR", "mass": { "chemical_mass": 29138.0, "monoisotopic_mass": 29138.0 }, "refseq": { "ac": "XP_035299008", "name": "membrane-anchored junction protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299008" }, "gene_names": [ { "name": "Majin", "type": "recommended", "evidence": [ { "id": "A0A8C2MVW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVW3" } ] }, { "name": "Majin", "type": "synonym", "evidence": [ { "id": "XP_035299008", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299008" } ] } ], "protein_names": [ { "name": "Membrane-anchored junction protein", "type": "synonym", "evidence": [ { "id": "A0A8C2MVW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVW3/entry#names_and_taxonomy" } ] }, { "name": "membrane-anchored junction protein", "type": "synonym", "evidence": [ { "id": "XP_035299008", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299008" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035299008", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299008" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVW3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVW3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Majin", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVW3", "locus": {} } ], "crossref": [ { "id": "100759463", "url": "https://www.ncbi.nlm.nih.gov/gene/100759463", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759463", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759463", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HLKFKHE", "url": "https://omabrowser.org/oma/group/HLKFKHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MVW3", "url": "https://www.orthodb.org/?gene=A0A8C2MVW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35824", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35824", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35824:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35824:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15077", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15077", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035299008", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299008", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MVW3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MVW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLKPFTYPFPETRFLHAGSKVYKFKIRYGDSIRGEEIEDKEVIIQELEDSIRAVLANMDNLQPFVTEHFIVFPYKSKWERVSHLKFKHGEIILTPYPFVFTLYVEMKWFTGSLPSGKPIDDIPLELVLAEKKAEEATMRKRKLVEEPSSPSRPGPHRAKRETSSEAFSNMKPLKETKRTREGEAQQEYQDTPASDATDGQEQDSKLGHSLPGLVVPPLQHSNPPPPREPGASGFFGFLSTLFPFRYFFRKSSQ", "length": 254, "header": "tr|A0A8C2MVW3-1|A0A8C2MVW3_CRIGR Isoform 1 of Membrane-anchored junction protein OS=Cricetulus griseus OX=10029 GN=Majin PE=4 SV=1 CANONICAL=A0A8C2MVW3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MVW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVW3/entry#A0A8C2MVW3-1", "sequence": { "sequence": "MSLKPFTYPFPETRFLHAGSKVYKFKIRYGDSIRGEEIEDKEVIIQELEDSIRAVLANMDNLQPFVTEHFIVFPYKSKWERVSHLKFKHGEIILTPYPFVFTLYVEMKWFTGSLPSGKPIDDIPLELVLAEKKAEEATMRKRKLVEEPSSPSRPGPHRAKRETSSEAFSNMKPLKETKRTREGEAQQEYQDTPASDATDGQEQDSKLGHSLPGLVVPPLQHSNPPPPREPGASGFFGFLSTLFPFRYFFRKSSQ", "length": 254, "header": "tr|A0A8C2MVW3-1|A0A8C2MVW3_CRIGR Isoform 1 of Membrane-anchored junction protein OS=Cricetulus griseus OX=10029 GN=Majin PE=4 SV=1 CANONICAL=A0A8C2MVW3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVW3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVW3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MVW3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVW3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759463", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759463", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6AYM7-1", "protein_name": "Membrane-anchored junction protein", "gene_name": "Majin", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLKPFTYPFPETRFLHAGTNVYKFKIRYGNSIRGEEIEDKGVIIQELEDSIRAVLANMDSLQPFVTEHFIVFPYKSKWERVSHLKFKHGEIILTPYPFVFTLYIEMKCFAESLPSGKPTDDIPLELVLTAKEAEEATMRKRKLMEEPSTPSRPGPHRAKMETWSEASSTKKALKEHKRSWGEDSQQDTPASDSTAVTEQDPMLGHSLPGLVVPPLEHSNPPPLKEPAARGFLGFLSALFPFRYFFRKSTQ", "length": 251 }, "evidence": [ { "id": "A0A8C2MVW3", "url": 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269477", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269477" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW17", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW17" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Usp12", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW17", "locus": {} } ], "crossref": [ { "id": "cd02663", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02663", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764216", "url": "https://www.ncbi.nlm.nih.gov/gene/100764216", "database": "GeneID", "categories": [ "Genome 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"database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FVK6", "url": "https://www.orthodb.org/?gene=A0A9J7FVK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006:SF647", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006:SF647", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269477", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269477", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MW17", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": 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"tr|A0A9J7FVK6-1|A0A8C2MW17_CRIGR Computationally mapped isoform of ubiquitinyl hydrolase 1 OS=Cricetulus griseus OX=10029 GN=Usp12 PE=3 SV=1 CANONICAL=A0A8C2MW17-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZ21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW17/entry#A0A9J7GZ21-1", "sequence": { "sequence": "MEILMTVSKFASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKENLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLRNGDVDTEDNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGRK", "length": 312, "header": "tr|A0A9J7GZ21-1|A0A9J7GZ21_CRIGR Computationally mapped isoform of ubiquitinyl hydrolase 1 OS=Cricetulus griseus OX=10029 GN=Usp12 PE=3 SV=1 CANONICAL=A0A8C2MW17-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764216", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764216", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW17", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW17" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW17", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW17" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW17", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW17" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW17", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW17" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW17", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW17" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW17", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MW17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW17" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 369, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 164, "end_pos": 166 }, { "start_pos": 182, "end_pos": 184 }, { "start_pos": 19, "end_pos": 21 }, { "start_pos": 209, "end_pos": 211 }, { "start_pos": 288, "end_pos": 290 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MW20-1", "uniprot_ac": "A0A8C2MW20", "uniprot_id": "A0A8C2MW20_CRIGR", "mass": { "chemical_mass": 91965.0, "monoisotopic_mass": 91965.0 }, "refseq": { "ac": "XP_003507275", "name": "CSC1-like protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507275" }, "gene_names": [ { "name": "Tmem63a", "type": "recommended", "evidence": [ { "id": "A0A8C2MW20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW20" } ] }, { "name": "Tmem63a", "type": "synonym", "evidence": [ { "id": "XP_003507275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507275" } ] } ], "protein_names": [ { "name": "CSC1-like protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003507275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507275" }, { "id": "A0A8C2MW20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW20/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614340.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003507275.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003507275", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507275" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW20", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW20" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem63a", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW20", "locus": {} } ], "crossref": [ { "id": "100751086", "url": "https://www.ncbi.nlm.nih.gov/gene/100751086", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751086", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751086", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MW20", "url": "https://www.orthodb.org/?gene=A0A8C2MW20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G2C1", "url": "https://www.orthodb.org/?gene=A0A9J7G2C1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13018:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13018:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13967", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13967", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14703", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14703", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003507275", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507275", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MW20", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MW20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2R6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMTSYPFLDPRQSKAVSIRGSLALGDHHNDSYCYSSVRNSSTVLQGVTFGGVPTVLLIDVICFLFLVLVFSFIRRRFWDYGRIALVSEAGSEARFQRSLSSSSGQHDFENELGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHLIFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGRTTIANLQTNNDLLWLHTVFSVIYLLLTVGFMWHHTRSIRYKEENLVRQTLFITGLPREARKETVESHFRNAYPTCEVVDVQLCYSVAKLMHLCRERRKAEKSLAYYTNLQAKTGRLTLINPKTCGQFCCCEVRGCEREDAISYYTQMNDSLLERIAAEECRVQDQPLGMAFVTFREKSMATFILKDFNACKCQGFRCKGEPQPSSYSRELCVSKWTVSFASYPEDICWKNLSIQGVRWWLQWLGINFSLFVVLFFLTTPSIIISTMDKFNVTKPIHALNNPVISQFFPTLLLWSFSALLPSIVYYSTLLESHWTRSGENRIMVSKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSDGSIRLECVFLPDQGAFFVNYVIASAFIGSGMELVRLPGLILYTFRMIMAKTAADRRNVKQNQAFEYEFGAMYAWILCVFTVIMAYSITCPIIVPFGLIYILLKHMVDRHNLYFAYLPAKLEKRIHFAAVNQALAAPILCLFWLFFYSFLRLGLKAPATLFTFLVVLLTILACLLYTCFGCFKHLSPRNYKTEESASDKGSEAEAHVPPPFTPYVPRILNGLASERTALSPQQQQTYGAIRHISGTLPGHLVAQNSSDSVASIDQES", "length": 806, "header": "tr|A0A8C2MW20-1|A0A8C2MW20_CRIGR Isoform 1 of CSC1-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tmem63a PE=3 SV=1 CANONICAL=A0A8C2MW20-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MW20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW20/entry#A0A8C2MW20-1", "sequence": { "sequence": "MMTSYPFLDPRQSKAVSIRGSLALGDHHNDSYCYSSVRNSSTVLQGVTFGGVPTVLLIDVICFLFLVLVFSFIRRRFWDYGRIALVSEAGSEARFQRSLSSSSGQHDFENELGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHLIFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGRTTIANLQTNNDLLWLHTVFSVIYLLLTVGFMWHHTRSIRYKEENLVRQTLFITGLPREARKETVESHFRNAYPTCEVVDVQLCYSVAKLMHLCRERRKAEKSLAYYTNLQAKTGRLTLINPKTCGQFCCCEVRGCEREDAISYYTQMNDSLLERIAAEECRVQDQPLGMAFVTFREKSMATFILKDFNACKCQGFRCKGEPQPSSYSRELCVSKWTVSFASYPEDICWKNLSIQGVRWWLQWLGINFSLFVVLFFLTTPSIIISTMDKFNVTKPIHALNNPVISQFFPTLLLWSFSALLPSIVYYSTLLESHWTRSGENRIMVSKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSDGSIRLECVFLPDQGAFFVNYVIASAFIGSGMELVRLPGLILYTFRMIMAKTAADRRNVKQNQAFEYEFGAMYAWILCVFTVIMAYSITCPIIVPFGLIYILLKHMVDRHNLYFAYLPAKLEKRIHFAAVNQALAAPILCLFWLFFYSFLRLGLKAPATLFTFLVVLLTILACLLYTCFGCFKHLSPRNYKTEESASDKGSEAEAHVPPPFTPYVPRILNGLASERTALSPQQQQTYGAIRHISGTLPGHLVAQNSSDSVASIDQES", "length": 806, "header": "tr|A0A8C2MW20-1|A0A8C2MW20_CRIGR Isoform 1 of CSC1-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tmem63a PE=3 SV=1 CANONICAL=A0A8C2MW20-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G2C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW20/entry#A0A9J7G2C1-1", "sequence": { "sequence": "MSSAFCEARFQRSLSSSSGQHDFENELGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHLIFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGRTTIANLQTNNDLLWLHTVFSVIYLLLTVGFMWHHTRSIRYKEENLVRQTLFITGLPREARKETVESHFRNAYPTCEVVDVQLCYSVAKLMHLCRERRKAEKSLAYYTNLQAKTGRLTLINPKTCGQFCCCEVRGCEREDAISYYTQMNDSLLERIAAEECRVQDQPLGMAFVTFREKSMATFILKDFNACKCQGFRCKGEPQPSSYSRELCVSKWTVSFASYPEDICWKNLSIQGVRWWLQWLGINFSLFVVLFFLTTPSIIISTMDKFNVTKPIHALNNPVISQFFPTLLLWSFSALLPSIVYYSTLLESHWTRSGENRIMVSKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSDGSIRLECVFLPDQGAFFVNYVIASAFIGSGMELVRLPGLILYTFRMIMAKTAADRRNVKQNQAFEYEFGAMYAWILCVFTVIMAYSITCPIIVPFGLIYILLKHMVDRHNLYFAYLPAKLEKRIHFAAVNQALAAPILCLFWLFFYSFLRLGLKAPATLFTFLVVLLTILACLLYTCFGCFKHLSPRNYKTEESASDKGSEAEAHVPPPFTPYVPRILNGLASERTALSPQQQQTYGAIRHISGTLPGHLVAQNSSDSVASIDQES", "length": 721, "header": "tr|A0A9J7G2C1-1|A0A8C2MW20_CRIGR Computationally mapped isoform of CSC1-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tmem63a PE=3 SV=1 CANONICAL=A0A8C2MW20-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G2R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW20/entry#A0A9J7G2R6-1", "sequence": { "sequence": "MLPLADCHLPPARHLIFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGRTTIANLQTNNDLLWLHTVFSVIYLLLTVGFMWHHTRSIRYKEENLVRQTLFITGLPREARKETVESHFRNAYPTCEVVDVQLCYSVAKLMHLCRERRKAEKSLAYYTNLQAKTGRLTLINPKTCGQFCCCEVRGCEREDAISYYTQMNDSLLERIAAEECRVQDQPLGMAFVTFREKSMATFILKDFNACKCQGFRCKGEPQPSSYSRELCVSKWTVSFASYPEDICWKNLSIQGVRWWLQWLGINFSLFVVLFFLTTPSIIISTMDKFNVTKPIHALNNPVISQFFPTLLLWSFSALLPSIVYYSTLLESHWTRSGENRIMVSKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSDGSIRLECVFLPDQGAFFVNYVIASAFIGSGMELVRLPGLILYTFRMIMAKTAADRRNVKQNQAFEYEFGAMYAWILCVFTVIMAYSITCPIIVPFGLIYILLKHMVDRHNLYFAYLPAKLEKRIHFAAVNQALAAPILCLFWLFFYSFLRLGLKAPATLFTFLVVLLTILACLLYTCFGCFKHLSPRNYKTEESASDKGSEAEAHVPPPFTPYVPRILNGLASERTALSPQQQQTYGAIRHISGTLPGHLVAQNSSDSVASIDQES", "length": 674, "header": "tr|A0A9J7G2R6-1|A0A8C2MW20_CRIGR Computationally mapped isoform of CSC1-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tmem63a PE=3 SV=1 CANONICAL=A0A8C2MW20-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"url": "https://www.uniprot.org/uniprotkb/A0A8C2MW20" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW20", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW20" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW20", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW20" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW20", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW20" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { 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"MEAATAPEAALRPTLKVKEASPADADGPQASPRRGTGSPLSQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTRDGCALDTSRVSVRNGERDSILFIREAQRADSGRYQLSVQLGGLEATATIDILVIERPGPPQSIKLVDVWGSSATLEWTPPQDTGNAALLGYTVQKADTKSGLWFTVLERCRRASCTVPNLIVGNSYTFRVFAENQCGLSENAPITADLAHIQKAATVYRTEGFAQRDFSEAPKFTQPLADCTTVIGYDTQLFCCVRASPKPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKAPN", "length": 354 }, "evidence": [ { "id": "A0A8C2MW21", "url": "https://omabrowser.org/oma/group/A0A8C2MW21/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5FW53-1", "protein_name": "Myosin-binding protein H-like", "gene_name": "Mybphl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METATTLEIASCSQRQVEAAADPADAKGPRTSHQQEAGSPSLQLLPSIEEHPKIWLPRALKQTYIRKAGETVNLLIPIQGKPKPQTTWTHNGCALDSSRVSVRNGEHDSILFIREAQRTDSGCYQLCVQLGGLQATATINILVIEKPGPPQSIKLVDVWGANATLEWTPPQDTGNTALLGYTVQKADKKSGLWFTVLERYHRTSCVVSNLIVGNSYAFRVFAENQCGLSDTAPVTADLAHIQKAATVYKAKGFAQRDLSEAPKFTQPLADCTTVTGYDTQLFCCVRASPRPKIIWLKNKMDLQGNPKYRALSQLGICSLEIRKPSPFDGGIYTCKAINALGEASVDCRVDVKAPH", "length": 355 }, "evidence": [ { "id": "A0A8C2MW21", "url": "https://omabrowser.org/oma/group/A0A8C2MW21/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5PQM4-1", "protein_name": "Myosin-binding protein H-like", "gene_name": "Mybphl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METATTLEIASCSQRQVEEAADPADAEGPQTTRQQEAGSPSLQLLPSIEEHPKIWLPRALRQTYIRKVGETVNLLIPFQGKPKPQTIWTHNGSALDNSRVSVRNGEHDSILFIREAQRTDSGCYQLCVQLGGLQATATINILVIEKPGPPQSIKLVDVWGANATLEWTPPQDTGNTALLGYTVQKADKKSGLWFTVLERYHRTSCIVSDLIVGNSYAFRVFAENQCGLSDTAPVTADLAHIQKAATVYKAKGFAQRDLSEAPKFTQPLADCTTVTGYDTQLFCCVRASPKPKIIWLKNKMDLQGNPKYRALSQLGICSLEIRKPSPFDGGIYTCKAINALGEASVDCRVDVKAPH", "length": 355 }, "evidence": [ { "id": "A0A8C2MW21", "url": "https://omabrowser.org/oma/group/A0A8C2MW21/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW21", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW21" } ], "pmid": "" }, { "name": "myofilament", "id": "GO:0036379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036379", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW21", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW21" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW21", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW21" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 144, "end_pos": 239, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW21" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 135, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 157, "end_pos": 159 }, { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MW27-1", "uniprot_ac": "A0A8C2MW27", "uniprot_id": "A0A8C2MW27_CRIGR", "mass": { "chemical_mass": 75157.0, "monoisotopic_mass": 75157.0 }, "refseq": { "ac": "XP_007643421", "name": "zinc finger protein 709-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643421" }, "gene_names": [ { "name": "LOC100755972", "type": "recommended", "evidence": [ { "id": "A0A8C2MW27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27" } ] }, { "name": "LOC100755972", "type": "synonym", "evidence": [ { "id": "XP_007643421", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643421" } ] } ], "protein_names": [ { "name": "Zinc finger protein 709-like isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2MW27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 709-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007643421", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643421" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614083.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007643421", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643421" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100755972", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27", "locus": {} } ], "crossref": [ { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755972", "url": "https://www.ncbi.nlm.nih.gov/gene/100755972", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755972", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755972", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NIEHEYE", "url": "https://omabrowser.org/oma/group/NIEHEYE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MW27", "url": "https://www.orthodb.org/?gene=A0A8C2MW27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G836", "url": "https://www.orthodb.org/?gene=A0A9J7G836", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23232:SF158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23232:SF158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24376", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24376", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24376:SF155", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24376:SF155", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007643421", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643421", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MW27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MW27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G836", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G836", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G836-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G836-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESVTFEDVAVNFTLEEWAMLDSSQKDLYKDVMQETLRNLASIGNKWEHQNIEHEYENLWRKLSSQLLERLCEYTEGRQCTEVFNWIPEYVGNQKSHPGVPTYESHVYGEVVIGHLSLNVPPHLHPGHKPYGTQEYGKELYKHKEFGGTSSSSTTFQKHKRIHTGEKPETSHCNEEVRCLISSQNNEKTSTGEKQYECKQCGKVFTSSSSFRRHEEYHSREKSYVCKQCGKAFPFPSSLQIHERIHTGEKPYMCKQCGKTFARSSSLLTHERIHTGEKPYVCKQCGKAFTDRSSLRFHEMMHSGEKPYKCTKCGKAFASSGAFRKHERTHTGEQLFVCLQCEKVFSCESAFRTHKIIHSGECVCKQCGKAFTSHSSVKYHELMHSGEKPYVCKQCGKTFRSPKQVQIHKRTHTGEKPYVCKECGKAFTFLGSLQYHELIHTGEKPYLCKQCGKAFRSSRQVQIHERTHTGEKPYICKQCGKAFFSLYHLRRHEVIHSGMNPYVCKQCGKSFSWFSTFHSHKQTHTGEKPYLCKQCGKAFCSRISWRRHEKAHTTVKPYACVQCGKAFRSPSYLKIHERIHTGEKPFICSQCGKPFRSFRYVKSHERSHTGEKPFVCTECGKAFSYYSSFHRHRRTHQTVTLNTELEKTS", "length": 649, "header": "tr|A0A8C2MW27-1|A0A8C2MW27_CRIGR Isoform 1 of Zinc finger protein 709-like isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100755972 PE=3 SV=1 CANONICAL=A0A8C2MW27-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MW27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27/entry#A0A8C2MW27-1", "sequence": { "sequence": "MESVTFEDVAVNFTLEEWAMLDSSQKDLYKDVMQETLRNLASIGNKWEHQNIEHEYENLWRKLSSQLLERLCEYTEGRQCTEVFNWIPEYVGNQKSHPGVPTYESHVYGEVVIGHLSLNVPPHLHPGHKPYGTQEYGKELYKHKEFGGTSSSSTTFQKHKRIHTGEKPETSHCNEEVRCLISSQNNEKTSTGEKQYECKQCGKVFTSSSSFRRHEEYHSREKSYVCKQCGKAFPFPSSLQIHERIHTGEKPYMCKQCGKTFARSSSLLTHERIHTGEKPYVCKQCGKAFTDRSSLRFHEMMHSGEKPYKCTKCGKAFASSGAFRKHERTHTGEQLFVCLQCEKVFSCESAFRTHKIIHSGECVCKQCGKAFTSHSSVKYHELMHSGEKPYVCKQCGKTFRSPKQVQIHKRTHTGEKPYVCKECGKAFTFLGSLQYHELIHTGEKPYLCKQCGKAFRSSRQVQIHERTHTGEKPYICKQCGKAFFSLYHLRRHEVIHSGMNPYVCKQCGKSFSWFSTFHSHKQTHTGEKPYLCKQCGKAFCSRISWRRHEKAHTTVKPYACVQCGKAFRSPSYLKIHERIHTGEKPFICSQCGKPFRSFRYVKSHERSHTGEKPFVCTECGKAFSYYSSFHRHRRTHQTVTLNTELEKTS", "length": 649, "header": "tr|A0A8C2MW27-1|A0A8C2MW27_CRIGR Isoform 1 of Zinc finger protein 709-like isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100755972 PE=3 SV=1 CANONICAL=A0A8C2MW27-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G836-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27/entry#A0A9J7G836-1", "sequence": { "sequence": "MESVTFEDVAVNFTLEEWAMLDSSQKDLYKDVMQETLRNLASIGNKWEHQNIEHEYENLWRKLR", "length": 64, "header": "tr|A0A9J7G836-1|A0A8C2MW27_CRIGR Computationally mapped isoform of Zinc finger protein 709-like isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100755972 PE=3 SV=1 CANONICAL=A0A8C2MW27-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G836", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G836" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G836", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G836" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755972", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755972", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K1C4-1", "protein_name": "Zinc finger protein 799", "gene_name": "Zfp799", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVTLEDVAVDFTLEEWTMLNLWQKQLYKEVMQDTLRNLCYIGNKQEHQNIENEYENLWKKLSSQLLEKLCEYTEGHQCAEIFTWAPECAGNQKSCPGVPPYESHVYEEVVIGHLSLNVPPHSHPGHKPYDVQECGKELYKHKESGSTSNPSTPFQKQRRVHAEEKPETSHCKEDSRCLIFSHNDDRTSSGEQHYECKQCGKVFTSASSFRRHEEYHSREKAYVCKQCGKAFPFPSSLQIHERIHTGEKPYTCKQCGKTFARSSSLLTHERIHTGEKPYVCKQCGKAFTDRSSLRFHEMMHSGEKPYKCTKCGKAFASSGAFRKHERTHTGEQLFVCLQCEKVFSCESAFRTHKIIHSGECVCKQCGKAFTSHSSVKYHELMHSGEKPYVCKQCGKTFRSPKQVQIHKRTHTGEKPYVCKECGKAFTFLGSLQYHELIHTGEKPYLCKQCGKAFRSSRQVQIHERTHTGEKPYVCKQCGKAFFSLYHLRRHEVIHSGTNPYVCKQCGKAFSWFSTFHSHKQTHTGEKPYLCKQCGKAFCSRISWRRHEKAHTTVKPYACVQCGKAFRSPSYLKIHERIHTGEKPFICSQCGKPFRSFRYVKSHERSHTGEKPFVCTECGKAFSYYSSFHRHRRTHQTVTLNTELEKTS", "length": 649 }, "evidence": [ { "id": "A0A8C2MW27", "url": "https://omabrowser.org/oma/group/A0A8C2MW27/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MW27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 141, "end_pos": 168, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MW27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW27" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 86, "start_aa": "Val", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MW37-1", "uniprot_ac": "A0A8C2MW37", "uniprot_id": "A0A8C2MW37_CRIGR", "mass": { "chemical_mass": 57350.0, "monoisotopic_mass": 57350.0 }, "refseq": { "ac": "XP_027246009", "name": "serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246009" }, "gene_names": [ { "name": "Ppp3cc", "type": "recommended", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ] }, { "name": "Ppp3cc", "type": "synonym", "evidence": [ { "id": "XP_027246009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246009" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein phosphatase", "type": "recommended", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X6", "type": "synonym", "evidence": [ { "id": "XP_027246009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246009" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027246009", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246009" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW37", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ppp3cc", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37", "locus": {} } ], "crossref": [ { "id": "cd07416", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07416", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751412", "url": "https://www.ncbi.nlm.nih.gov/gene/100751412", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751412", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751412", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MW37", "url": "https://www.orthodb.org/?gene=A0A8C2MW37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7F2F4", "url": "https://www.orthodb.org/?gene=A0A9J7F2F4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45673", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45673", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00149", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00149", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027246009", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246009", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MW37", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MW37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EXU7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EXU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2Z9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J9C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J9C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9C1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGSHPQFSTTDRVIKAVPFPPTQRLTLTEVFENGKPKMDVLKNHLVKEGRVEEEVALKIINDGAAILRQEMTMIEVDAPITVCGDIHGQFFDLMKLFEVGGPPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINYPKTLFLLRGNHECRHLTEYFTFKQECRIKYSEMVYEACMNTFDCLPLAALLNQQFLCVHGGMSPEINCLDDIRKLDRFTEPPAFGPVCDLLWSDPLEEYGSEKNQEHYSHNTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDDELISEDDTEGVSSVRKEIIKNKIRAIGKMARVFSVLREESESVLTLKGLTPTGTLPLGVLSGGKQTIESATAQATQEAVRGYPHRIRTFEEARGLDRINERMPPRKEGGQLDGPVKTVHHSHAARRSIHGKKAP", "length": 505, "header": "tr|A0A8C2MW37-1|A0A8C2MW37_CRIGR Isoform 1 of Serine/threonine-protein phosphatase OS=Cricetulus griseus OX=10029 GN=Ppp3cc PE=3 SV=1 CANONICAL=A0A8C2MW37-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MW37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37/entry#A0A8C2MW37-1", "sequence": { "sequence": "MSGSHPQFSTTDRVIKAVPFPPTQRLTLTEVFENGKPKMDVLKNHLVKEGRVEEEVALKIINDGAAILRQEMTMIEVDAPITVCGDIHGQFFDLMKLFEVGGPPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINYPKTLFLLRGNHECRHLTEYFTFKQECRIKYSEMVYEACMNTFDCLPLAALLNQQFLCVHGGMSPEINCLDDIRKLDRFTEPPAFGPVCDLLWSDPLEEYGSEKNQEHYSHNTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDDELISEDDTEGVSSVRKEIIKNKIRAIGKMARVFSVLREESESVLTLKGLTPTGTLPLGVLSGGKQTIESATAQATQEAVRGYPHRIRTFEEARGLDRINERMPPRKEGGQLDGPVKTVHHSHAARRSIHGKKAP", "length": 505, "header": "tr|A0A8C2MW37-1|A0A8C2MW37_CRIGR Isoform 1 of Serine/threonine-protein phosphatase OS=Cricetulus griseus OX=10029 GN=Ppp3cc PE=3 SV=1 CANONICAL=A0A8C2MW37-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EXU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37/entry#A0A9J7EXU7-1", "sequence": { "sequence": "MSGSHPQFSTTDRVIKAVPFPPTQRLTLTEVFENGKPKMDVLKNHLVKEGRVEEEVALKIINDGAAILRQEMTMIEVDAPITVCGDIHGQFFDLMKLFEVGGPPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINYPKTLFLLRGNHECRHLTEYFTFKQECRIKYSEMVYEACMNTFDCLPLAALLNQQFLCVHGGMSPEINCLDDIRKLDRFTEPPAFGPVCDLLWSDPLEEYGSEKNQEHYSHNTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDDELISEDDTEGVSSVRKEIIKNKIRAIGKMARVFSVLREESESVLTLKGLTPTGTLPLGVLSGGKQTIESAVRGYPHRIRTFEEARGLDRINERMPPRKEGGQLDGPVKTVHHSHAARRSIHGKKAP", "length": 497, "header": "tr|A0A9J7EXU7-1|A0A8C2MW37_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase OS=Cricetulus griseus OX=10029 GN=Ppp3cc PE=3 SV=1 CANONICAL=A0A8C2MW37-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F2F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37/entry#A0A9J7F2F4-1", "sequence": { "sequence": "MDVLKNHLVKEGRVEEEVALKIINDGAAILRQEMTMIEVDAPITVCGDIHGQFFDLMKLFEVGGPPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINYPKTLFLLRGNHECRHLTEYFTFKQECRIKYSEMVYEACMNTFDCLPLAALLNQQFLCVHGGMSPEINCLDDIRKLDRFTEPPAFGPVCDLLWSDPLEEYGSEKNQEHYSHNTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDDELISEDDTEGVSSVRKEIIKNKIRAIGKMARVFSVLREESESVLTLKGLTPTGTLPLGVLSGGKQTIESATAQATQEAVRGYPHRIRTFEEARGLDRINERMPPRKEGGQLDGPVKTVHHSHAARRSIHGKKAP", "length": 467, "header": "tr|A0A9J7F2F4-1|A0A8C2MW37_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase OS=Cricetulus griseus OX=10029 GN=Ppp3cc PE=3 SV=1 CANONICAL=A0A8C2MW37-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F2Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37/entry#A0A9J7F2Z9-1", "sequence": { "sequence": "MSGSHPQFSTTDRVIKAVPFPPTQRLTLTEVFENGKPKMDVLKNHLVKEGRVEEEVALKIINDGAAILRQEMTMIEVDAPITVCGDIHGQFFDLMKLFEVGGPPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINYPKTLFLLRGNHECRHLTEYFTFKQECRIKYSEMVYEACMNTFDCLPLAALLNQQFLCVHGGMSPEINCLDDIRKLDRFTEPPAFGPVCDLLWSDPLEEYGSEKNQEHYSHNTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDDELISEDDTEGVSSVRKEIIKNKIRAIGKMARVFSVLREESESVLTLKGLTPTGTLPLGVLSGGKQTIESASHQEHRRGTNEHVYQRGCTWMFTGVLSWQPQIRSNSSASW", "length": 481, "header": "tr|A0A9J7F2Z9-1|A0A8C2MW37_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase OS=Cricetulus griseus OX=10029 GN=Ppp3cc PE=3 SV=1 CANONICAL=A0A8C2MW37-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HDV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37/entry#A0A9J7HDV9-1", "sequence": { "sequence": "MSGSHPQFSTTDRVIKAVPFPPTQRLTLTEVFENGKPKMDVLKNHLVKEGRVEEEVALKIINDGAAILRQEMTMIEVDAPITVCGDIHGQFFDLMKLFEVGGPPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINYPKTLFLLRGNHECRHLTEYFTFKQECRIKYSEMVYEACMNTFDCLPLAALLNQQFLCVHGGMSPEINCLDDIRKLDRFTEPPAFGPVCDLLWSDPLEEYGSEKNQEHYSHNTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDDELISEDDTEAVRGYPHRIRTFEEARGLDRINERMPPRKEGGQLDGPVKTVHHSHAARRSIHGKKAP", "length": 437, "header": "tr|A0A9J7HDV9-1|A0A9J7HDV9_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase OS=Cricetulus griseus OX=10029 GN=Ppp3cc PE=3 SV=1 CANONICAL=A0A8C2MW37-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J9C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37/entry#A0A9J7J9C1-1", "sequence": { "sequence": "MSGSHPQFSTTDRVIKAVPFPPTQRLTLTEVFENGKPKMDVLKNHLVKEGRVEEEVALKIINDGAAILRQEMTMIEVDAPITVCGDIHGQFFDLMKLFEVGGPPSNTRYLFLGDYVDRGYFSIEECRIKYSEMVYEACMNTFDCLPLAALLNQQFLCVHGGMSPEINCLDDIRKLDRFTEPPAFGPVCDLLWSDPLEEYGSEKNQEHYSHNTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDDELISEDDTEGVSSVRKEIIKNKIRAIGKMARVFSVLREESESVLTLKGLTPTGTLPLGVLSGGKQTIESATAQATQEAVRGYPHRIRTFEEARGLDRINERMPPRKEGGQLDGPVKTVHHSHAARRSIHGKKAP", "length": 469, "header": "tr|A0A9J7J9C1-1|A0A9J7J9C1_CRIGR Computationally mapped isoform of protein-serine/threonine phosphatase OS=Cricetulus griseus OX=10029 GN=Ppp3cc PE=3 SV=1 CANONICAL=A0A8C2MW37-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EXU7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXU7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EXU7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXU7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751412", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751412", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin-dependent protein phosphatase activity", "id": "GO:0033192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033192", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW37", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW37", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW37", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW37", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "calcineurin-NFAT signaling cascade", "id": "GO:0033173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033173", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW37", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ], "pmid": "" }, { "name": "calcineurin-mediated signaling", "id": "GO:0097720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097720", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW37", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GV48-1", "G3GWQ6-1", "G3H060-1", "G3H9Q0-1", "G3H7Z6-1", "G3I157-1", "G3HCQ6-1", "A0A8C2MA30-1", "G3HMJ7-1", "G3I434-1", "G3H622-1", "G3HKY7-1", "G3GRD1-1", "G3I4H5-1", "G3H8H2-1", "A0A9J7F890-1", "A0A8C2MW37-1", "A0A061I6V7-1", "A0A9J7GBP5-1", "A0A9J7JFN8-1", "A0A9J7G7W0-1", "A0A9J7GE78-1", "A0A061HVT3-1", "A0A061HX98-1", "A0A3L7HX32-1", "A0A8C2LYQ8-1", "A0A8C2M5N0-1", "A0A9J7JBH1-1", "A0A9J7EY47-1", "A0A8C2LGL9-1", "A0A8C2LVB9-1", "A0A8C2QH88-1", "A0A9J7F130-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FXD0-1", "A0A9J7G243-1", "A0A9J7GEM4-1", "A0A9J7G1B8-1", "A0A9J7K1J8-1", "A0A9J7K5S1-1", "A0A9J7EZL1-1", "A0A8C2QCP2-1", "A0A8C2LTP5-1", "A0A8C2N2E5-1", "A0A8C2QBZ1-1", "A0A3L7HBF4-1", "A0A9J7GK96-1", "A0A8C2LI03-1", "A0A9J7G0U7-1", "A0A9J7GD33-1", "A0A9J7H9S5-1", "A0A9J7HCJ8-1", "A0A9J7GJY7-1", "A0A9J7JYW1-1", "A0A3L7I513-1", "A0A9J7FKB3-1", "A0A8C2LGY1-1", "A0A3L7HEM4-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GV48-1", "G3GWQ6-1", "G3H060-1", "G3H9Q0-1", "G3H622-1", "G3HKY7-1", "G3H7Z6-1", "G3I157-1", "G3HCQ6-1", "A0A8C2MA30-1", "G3HMJ7-1", "A0A8C2MF90-1", "A0A9J7GX39-1", "G3I434-1", "G3GRD1-1", "G3I4H5-1", "G3H8H2-1", "A0A9J7F890-1", "A0A8C2MW37-1", "A0A061I6V7-1", "A0A9J7GBP5-1", "A0A9J7JFN8-1", "A0A9J7G7W0-1", "A0A9J7GE78-1", "A0A061HX98-1", "A0A3L7HEJ5-1", "A0A3L7HX32-1", "A0A8C2LYQ8-1", "A0A8C2M5N0-1", "A0A9J7JBH1-1", "A0A8C2ME51-1", "A0A8C2MTQ0-1", "A0A3L7IJ01-1", "A0A9J7EY47-1", "A0A8C2LGL9-1", "A0A8C2LVB9-1", "A0A8C2QH88-1", "A0A9J7F130-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FXD0-1", "A0A9J7G243-1", "A0A9J7GEM4-1", "A0A9J7G1B8-1", "A0A9J7K1J8-1", "A0A9J7K5S1-1", "A0A9J7EZL1-1", "A0A9J7F6Q7-1", "A0A8C2N2E5-1", "A0A8C2LTP5-1", "A0A8C2QBZ1-1", "A0A8C2QCP2-1", "A0A3L7HBF4-1", "A0A3L7HC66-1", "A0A9J7GK96-1", "A0A8C2LI03-1", "A0A9J7G0U7-1", "A0A9J7GD33-1", "A0A9J7H9S5-1", "A0A9J7HCJ8-1", "A0A9J7GJY7-1", "A0A9J7JXQ8-1", "A0A9J7JYW1-1", "A0A9J7FKB3-1", "A0A8C2LGY1-1", "A0A3L7HEM4-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HVT3", "gene_name": "Ppm1k", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.52", "activity": "O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + H2O = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.52", "activity": "", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] } ] }, { "uniprot_ac": "A0A061HX98", "gene_name": "Dusp9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] } ] }, { "uniprot_ac": "A0A061I6V7", "gene_name": "Pgam5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061I6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6V7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061I6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6V7" } ] } ] }, { "uniprot_ac": "A0A3L7HBF4", "gene_name": "Cpped1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBF4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBF4" } ] } ] }, { "uniprot_ac": "A0A3L7HC66", "gene_name": "Ppp6c", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HC66" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HC66" } ] } ] }, { "uniprot_ac": "A0A3L7HEJ5", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] } ] }, { "uniprot_ac": "A0A3L7HEM4", "gene_name": "Ctdspl2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEM4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEM4" } ] } ] }, { "uniprot_ac": "A0A3L7HX32", "gene_name": "Dusp8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] } ] }, { "uniprot_ac": "A0A3L7I513", "gene_name": "Pdxp", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] } ] }, { "uniprot_ac": "A0A3L7IJ01", "gene_name": "Ppp2cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7IJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJ01" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7IJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJ01" } ] } ] }, { "uniprot_ac": "A0A8C2LGL9", "gene_name": "Ppp1cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LGL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGL9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LGL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGL9" } ] } ] }, { "uniprot_ac": "A0A8C2LGY1", "gene_name": "Ppp1ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LGY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGY1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LGY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGY1" } ] } ] }, { "uniprot_ac": "A0A8C2LI03", "gene_name": "Ctdsp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI03" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI03" } ] } ] }, { "uniprot_ac": "A0A8C2LTP5", "gene_name": "LOC100752571", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LTP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTP5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LTP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTP5" } ] } ] }, { "uniprot_ac": "A0A8C2LVB9", "gene_name": "Dusp22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] } ] }, { "uniprot_ac": "A0A8C2LYQ8", "gene_name": "Ppm1l", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYQ8" } ] } ] }, { "uniprot_ac": "A0A8C2M5N0", "gene_name": "Ppp1cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2M5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5N0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2M5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5N0" } ] } ] }, { "uniprot_ac": "A0A8C2MA30", "gene_name": "Phlpp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MA30" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MA30" } ] } ] }, { "uniprot_ac": "A0A8C2ME51", "gene_name": "Ppm1g", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2ME51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ME51" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2ME51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ME51" } ] } ] }, { "uniprot_ac": "A0A8C2MF90", "gene_name": "Ssh2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MF90" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MF90" } ] } ] }, { "uniprot_ac": "A0A8C2MTQ0", "gene_name": "Ssh1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTQ0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTQ0" } ] } ] }, { "uniprot_ac": "A0A8C2MW37", "gene_name": "Ppp3cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ] } ] }, { "uniprot_ac": "A0A8C2N2E5", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] } ] }, { "uniprot_ac": "A0A8C2QBZ1", "gene_name": "Ctdspl", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QBZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QBZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ] } ] }, { "uniprot_ac": "A0A8C2QCP2", "gene_name": "Dusp28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] } ] }, { "uniprot_ac": "A0A8C2QH88", "gene_name": "Dusp12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] } ] }, { "uniprot_ac": "A0A9J7EY47", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] } ] }, { "uniprot_ac": "A0A9J7EZL1", "gene_name": "LOC113830718", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] } ] }, { "uniprot_ac": "A0A9J7F130", "gene_name": "LOC100769947", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F130" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F130" } ] } ] }, { "uniprot_ac": "A0A9J7F6Q7", "gene_name": "LOC103164195", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F6Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6Q7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F6Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6Q7" } ] } ] }, { "uniprot_ac": "A0A9J7F890", "gene_name": "Ctdsp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F890" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F890" } ] } ] }, { "uniprot_ac": "A0A9J7FKB3", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] } ] }, { "uniprot_ac": "A0A9J7FMB0", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] } ] }, { "uniprot_ac": "A0A9J7FWJ6", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FXD0", "gene_name": "Ppm1f", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXD0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXD0" } ] } ] }, { "uniprot_ac": "A0A9J7G0U7", "gene_name": "Pptc7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ] } ] }, { "uniprot_ac": "A0A9J7G1B8", "gene_name": "Phlpp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B8" } ] } ] }, { "uniprot_ac": "A0A9J7G243", "gene_name": "Ppm1a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G243" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G243" } ] } ] }, { "uniprot_ac": "A0A9J7G7W0", "gene_name": "Ptpmt1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.27", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] } ] }, { "uniprot_ac": "A0A9J7GBP5", "gene_name": "Rpap2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GBP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GBP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP5" } ] } ] }, { "uniprot_ac": "A0A9J7GD33", "gene_name": "Ublcp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GD33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GD33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ] } ] }, { "uniprot_ac": "A0A9J7GE78", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] } ] }, { "uniprot_ac": "A0A9J7GEM4", "gene_name": "Ppm1e", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEM4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEM4" } ] } ] }, { "uniprot_ac": "A0A9J7GJY7", "gene_name": "Ppef1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJY7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJY7" } ] } ] }, { "uniprot_ac": "A0A9J7GK96", "gene_name": "Ppm1n", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK96" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK96" } ] } ] }, { "uniprot_ac": "A0A9J7GX39", "gene_name": "Ssh3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GX39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX39" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GX39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX39" } ] } ] }, { "uniprot_ac": "A0A9J7H9S5", "gene_name": "LOC100752571", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7H9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5" } ] } ] }, { "uniprot_ac": "A0A9J7HCJ8", "gene_name": "Ppp3cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7HCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7HCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JBH1", "gene_name": "Cdc14a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] } ] }, { "uniprot_ac": "A0A9J7JFN8", "gene_name": "Epm2a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] } ] }, { "uniprot_ac": "A0A9J7JXQ8", "gene_name": "Ppp2ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXQ8" } ] } ] }, { "uniprot_ac": "A0A9J7JYW1", "gene_name": "Ctdnep1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JYW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYW1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JYW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYW1" } ] } ] }, { "uniprot_ac": "A0A9J7K1J8", "gene_name": "LOC100761879", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7K1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1J8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7K1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1J8" } ] } ] }, { "uniprot_ac": "A0A9J7K5S1", "gene_name": "Ilkap", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7K5S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7K5S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S1" } ] } ] }, { "uniprot_ac": "G3GRD1", "gene_name": "Dusp10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MW47-1", "uniprot_ac": "A0A8C2MW47", "uniprot_id": "A0A8C2MW47_CRIGR", "mass": { "chemical_mass": 25176.0, "monoisotopic_mass": 25176.0 }, "refseq": { "ac": "XP_003514852", "name": "arpin isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514852" }, "gene_names": [ { "name": "LOC100753100", "type": "recommended", "evidence": [ { "id": "A0A8C2MW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW47" } ] }, { "name": "LOC100753100", "type": "synonym", "evidence": [ { "id": "XP_003514852", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514852" } ] } ], "protein_names": [ { "name": "Arpin", "type": "recommended", "evidence": [ { "id": "A0A8C2MW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW47/entry#names_and_taxonomy" } ] }, { "name": "arpin isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003514852", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514852" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 371 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616986.1) and transcript sequence (IACG01204133.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003514852.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003514852", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514852" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW47", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW47" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100753100", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW47", "locus": {} } ], "crossref": [ { "id": "100753100", "url": "https://www.ncbi.nlm.nih.gov/gene/100753100", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753100", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753100", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MW47", "url": "https://www.orthodb.org/?gene=A0A8C2MW47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31199", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31199", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31199:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31199:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10574", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10574", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003514852", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514852", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MW47", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MW47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHT6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHT6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRIYHDSVLRNKAVQSVRLQGTWDPAAHQGGNGVLLEGELVDVSQHSILDAHGRKDRYYVLYIRPSCIHRRKFDPKGNEIEPNFSATRKVNTGFLMSSYKTEAKGDTDRLTLEGLKGLVNKPELLELTKSLTPDQTVAFWMPESEMEAMELELGTGVRLKTRGDGPFIDSLAKLELGTVTKCNFAGDGKTGASWTDNIMAQKSSERATVEIREQGDGAEDEEWDD", "length": 226, "header": "tr|A0A8C2MW47-1|A0A8C2MW47_CRIGR Isoform 1 of Arpin OS=Cricetulus griseus OX=10029 GN=LOC100753100 PE=3 SV=1 CANONICAL=A0A8C2MW47-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MW47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW47/entry#A0A8C2MW47-1", "sequence": { "sequence": "MSRIYHDSVLRNKAVQSVRLQGTWDPAAHQGGNGVLLEGELVDVSQHSILDAHGRKDRYYVLYIRPSCIHRRKFDPKGNEIEPNFSATRKVNTGFLMSSYKTEAKGDTDRLTLEGLKGLVNKPELLELTKSLTPDQTVAFWMPESEMEAMELELGTGVRLKTRGDGPFIDSLAKLELGTVTKCNFAGDGKTGASWTDNIMAQKSSERATVEIREQGDGAEDEEWDD", "length": 226, "header": "tr|A0A8C2MW47-1|A0A8C2MW47_CRIGR Isoform 1 of Arpin OS=Cricetulus griseus OX=10029 GN=LOC100753100 PE=3 SV=1 CANONICAL=A0A8C2MW47-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW47/entry#A0A9J7JHT6-1", "sequence": { "sequence": "MSSYKTEAKGDTDRLTLEGLKGLVNKPELLELTKSLTPDQTVAFWMPESEMEAMELELGTGVRLKTRGDGPFIDSLAKLELGTVTKCNFAGDGKTGASWTDNIMAQKSSERATVEIREQGDGAEDEEWDD", "length": 130, "header": "tr|A0A9J7JHT6-1|A0A9J7JHT6_CRIGR Computationally mapped isoform of Arpin OS=Cricetulus griseus OX=10029 GN=LOC100753100 PE=3 SV=1 CANONICAL=A0A8C2MW47-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW47", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW47" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW47", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW47" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753100", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753100", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW47", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW47" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW47", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW47" } ], "pmid": "" }, { "name": "directional locomotion", "id": "GO:0033058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033058", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW47", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW47" } ], "pmid": "" }, { "name": "negative regulation of actin nucleation", "id": "GO:0051126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051126", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW47", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW47" } ], "pmid": "" }, { "name": "negative regulation of lamellipodium morphogenesis", "id": "GO:2000393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000393", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW47", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW47" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MW65-1", "uniprot_ac": "A0A8C2MW65", "uniprot_id": "A0A8C2MW65_CRIGR", "mass": { "chemical_mass": 23267.0, "monoisotopic_mass": 23267.0 }, "refseq": { "ac": "XP_003511639", "name": "ATP synthase subunit s, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511639" }, "gene_names": [ { "name": "Dmac2l", "type": "recommended", "evidence": [ { "id": "A0A8C2MW65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65" } ] }, { "name": "Dmac2l", "type": "synonym", "evidence": [ { "id": "XP_003511639", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511639" } ] } ], "protein_names": [ { "name": "ATP synthase subunit s, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8C2MW65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65/entry#names_and_taxonomy" } ] }, { "name": "ATP synthase subunit s, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_003511639", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511639" } ] }, { "name": "ATP synthase-coupling factor B", "type": "synonym", "evidence": [ { "id": "A0A8C2MW65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65/entry#names_and_taxonomy" } ] }, { "name": "Distal membrane arm assembly complex 2-like protein", "type": "synonym", "evidence": [ { "id": "A0A8C2MW65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65/entry#names_and_taxonomy" } ] }, { "name": "Mitochondrial ATP synthase regulatory component factor B", "type": "synonym", "evidence": [ { "id": "A0A8C2MW65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615169.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003511639", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511639" } ] }, { "annotation": "Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65#function" }, { "database": "UniProtKB", "id": "ARBA00023760", "url": "https://www.uniprot.org/uniprotkb/ARBA00023760#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dmac2l", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65", "locus": {} } ], "crossref": [ { "id": "100768179", "url": "https://www.ncbi.nlm.nih.gov/gene/100768179", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768179", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768179", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IFDMLYV", "url": "https://omabrowser.org/oma/group/IFDMLYV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MW65", "url": "https://www.orthodb.org/?gene=A0A8C2MW65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_003511639", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511639", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MW65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MW65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLFGKLSRQLCSLKKIPWSCDSRYFWEWLNTVFNKVDYERLRDVGPDRAASEWLLRCGAKVRYCGHQKWLQDYNSIPGGSMDKHKIQAIDATDSCIMDIGFDHMEGLELVEKITLCKCHYIDDNCLQRLSQFEKLRKSLLEMEIITCGNVTDNGIIALRHFRNLRYLFLSDLPGVKDKDNLVQVFKTALPSLELKLNLK", "length": 200, "header": "tr|A0A8C2MW65-1|A0A8C2MW65_CRIGR Isoform 1 of ATP synthase subunit s, mitochondrial OS=Cricetulus griseus OX=10029 GN=Dmac2l PE=3 SV=1 CANONICAL=A0A8C2MW65-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MW65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65/entry#A0A8C2MW65-1", "sequence": { "sequence": "MTLFGKLSRQLCSLKKIPWSCDSRYFWEWLNTVFNKVDYERLRDVGPDRAASEWLLRCGAKVRYCGHQKWLQDYNSIPGGSMDKHKIQAIDATDSCIMDIGFDHMEGLELVEKITLCKCHYIDDNCLQRLSQFEKLRKSLLEMEIITCGNVTDNGIIALRHFRNLRYLFLSDLPGVKDKDNLVQVFKTALPSLELKLNLK", "length": 200, "header": "tr|A0A8C2MW65-1|A0A8C2MW65_CRIGR Isoform 1 of ATP synthase subunit s, mitochondrial OS=Cricetulus griseus OX=10029 GN=Dmac2l PE=3 SV=1 CANONICAL=A0A8C2MW65-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768179", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768179", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZRY7-1", "protein_name": "ATP synthase subunit s, mitochondrial", "gene_name": "DMAC2L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRGAPLPHVGAAINGQWARAAKGEGQAGATVDARDAHSLPPSLRRYQMMLFGKVPRQLCALKKLPWSRDSRYFWGWLNAVFNKVDHERIRDVGPDRAASEWLLRCGAMVRYHGQERWQKDYNHLPTGPLDKYKIQAIDATDSCIMSIGFDHMEGLQYVEKIRFCKCHYIEDYCLERLSQIENLQKSMLEMEIISCGNITDKGIIALHHLRNLKYLFLSDLPGVKEKEKIVQAFKTSLPSLELKLDLK", "length": 247 }, "evidence": [ { "id": "A0A8C2MW65", "url": "https://omabrowser.org/oma/group/A0A8C2MW65/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A1ZAA9-1", "protein_name": "Uncharacterized protein", "gene_name": "ATPW", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLLLNKLPRITQLLARDPKDQRGIWGYVAVAFNQVDAERLSKVGANRLCAEWIIKNGGGVRFVESPSRLWKDYNSLPGENTQFCIKVVDASNSSIMKIGLEHLKDCRSIDTVIFHNCKHLENDGLEGLHHISSSLQRLQVSGCYNITDSGLAVIGELKNLRQLLIFDMIFVKNMEAVAASLKKQLPSCDIKATKMGLTLKPKE", "length": 203 }, "evidence": [ { "id": "A0A8C2MW65", "url": "https://omabrowser.org/oma/group/A0A8C2MW65/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "F1NBU5-1", "protein_name": "ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B)", "gene_name": "ATP5S", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLLGKLAQPARSLSERLSPGGCRRFWGWLNAVFNKVDYERIQAVGPDRAASEWLLRCGALVRYQGYEKWQQDYSGLPTGPLGKYKIEAINATESCIMYRGFDYLDGLEHVTEIKLQKCIYIQDECLQRLSETKNLQKSLLQLKIISCGNVTDKGIIALHKLTNLEYLYLSDLPGIRQKETTARVLQQALPNLELELDLD", "length": 199 }, "evidence": [ { "id": "A0A8C2MW65", "url": "https://omabrowser.org/oma/group/A0A8C2MW65/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P22027-1", "protein_name": "ATP synthase subunit s, mitochondrial", "gene_name": "DMAC2L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMLFGKISQQLCGLKKLPWSRDSRYFWGWLNAVFNKVDHDRIRDVGPDRAASEWLLRCGAMVRYHGQQRWQKDYNHLPTGPLDKYKIQAIDATDSCIMSIGFDHMEGLQYVEKIRLCKCHYIEDGCLERLSQLENLQKSMLEMEIISCGNVTDKGIIALHHFRNLKYLFLSDLPGVKEKEKIVQAFKTSLPSLELKLDLK", "length": 200 }, "evidence": [ { "id": "A0A8C2MW65", "url": "https://omabrowser.org/oma/group/A0A8C2MW65/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5XIM4-1", "protein_name": "ATP synthase subunit s, mitochondrial", "gene_name": "Dmac2l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMMFGKISRQLFSLKKIPWSCDSRYFWEWLNTVFNKVDYERIKDVGPDRAASEWLLRCGAKVRYCGHQKWLQDYNKLPGGSVDRYKIQAIDATDSCIMDIGFDHLVGLEHVERITLCRCHYIEDNCLQRLSQLENLRKSLLELEIIACGNVTDNGVIALRHFKNLKYLFLSDLPGIKDKEYLAEVFTKALPSLELKLNLK", "length": 200 }, "evidence": [ { "id": "A0A8C2MW65", "url": "https://omabrowser.org/oma/group/A0A8C2MW65/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99766-1", "protein_name": "ATP synthase subunit s, mitochondrial", "gene_name": "DMAC2L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMPFGKISQQLCGVKKLPWSCDSRYFWGWLNAVFNKVDYDRIRDVGPDRAASEWLLRCGAMVRYHGQERWQKDYNHLPTGPLDKYKIQAIDATDSCIMSIGFDHMEGLEHVEKIRLCKCHYIEDDCLLRLSQLENLQKTILEMEIISCGNITDKGIIALRHLRNLKYLLLSDLPGVREKENLVQAFKTALPSLELKLQLK", "length": 200 }, "evidence": [ { "id": "A0A8C2MW65", "url": "https://omabrowser.org/oma/group/A0A8C2MW65/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CRA7-1", "protein_name": "ATP synthase subunit s, mitochondrial", "gene_name": "Dmac2l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMMFGKISRQLCSLKKIPWSCDSRYFWEWLNTVFNKVDYERLRDVGPDRAASEWLLRCGAKVRYCGHQKWLHDYNTLPGSSIDRYKIQAIDATDSCIMDIGLDHMVGLEHVEKITLCKCHYIEDNCLQRLSQLENLRKSLLELEIIACGNVTDNGVIALRHFRNLKYLFLSDLPGVKDKEYLAQVFKTALPSLELKLNLK", "length": 200 }, "evidence": [ { "id": "A0A8C2MW65", "url": "https://omabrowser.org/oma/group/A0A8C2MW65/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65" } ], "pmid": "" }, { "name": "proton-transporting ATP synthase complex", "id": "GO:0045259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045259", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ATP biosynthetic process", "id": "GO:0006754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006754", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65" } ], "pmid": "" }, { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW65" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "A0A8C2MW73-1", "uniprot_ac": "A0A8C2MW73", "uniprot_id": "A0A8C2MW73_CRIGR", "mass": { "chemical_mass": 119139.0, "monoisotopic_mass": 119139.0 }, "refseq": { "ac": "XP_027253123", "name": "serine/threonine-protein kinase 11-interacting protein isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253123" }, "gene_names": [ { "name": "Stk11ip", "type": "recommended", "evidence": [ { "id": "A0A8C2MW73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73" } ] }, { "name": "Stk11ip", "type": "synonym", "evidence": [ { "id": "XP_027253123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253123" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein kinase 11-interacting protein", "type": "recommended", "evidence": [ { "id": "A0A8C2MW73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73/entry#names_and_taxonomy" } ] }, { "name": "LKB1-interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0A8C2MW73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein kinase 11-interacting protein isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027253123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253123" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027253123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253123" } ] }, { "annotation": "May regulate STK11/LKB1 function by controlling its subcellular localization.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F7M8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F7M8#function" }, { "database": "UniProtKB", "id": "ARBA00056490", "url": "https://www.uniprot.org/uniprotkb/ARBA00056490#function" }, { "database": "UniProtKB", "id": "A0A9J7FC18", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC18#function" }, { "database": "UniProtKB", "id": "A0A8C2MW73", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW73", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Stk11ip", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73", "locus": {} } ], "crossref": [ { "id": "100767028", "url": "https://www.ncbi.nlm.nih.gov/gene/100767028", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057288", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057288", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767028", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767028", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MW73", "url": "https://www.orthodb.org/?gene=A0A8C2MW73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15454:SF69", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15454:SF69", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15904", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15904", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23142", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23142", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25624", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25624", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027253123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253123", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MW73", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MW73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F7M8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F7M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F7M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F7M8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FC18", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FC18-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTAPRDSVVWKLAGLLRESGDAVLSGCSTLSLLTATLQQLNRVFELYLGPWGPGQTGFVALPSHPADSPIILQLQFLFDVLQKTLSLKLVHTPGAGLPGPIKIFPFKSLRQLELRGVPIHSLRGLRSIYSQLESLICSRSIQALEELLSACGGDLCSALPWLALLSADFSYNALTNLDSSLRLLSALRFLNLSHNHIQDCKGFLMDLSELYHLDISYNHLHLVPRVGPSGAALGILILRANELRSLQGLEQLRNLRHLDVAYNLLEGHTELSPLWLLAELRKLYLEGNPLWFHPAHRANTAQYLSPQARDAAHGFLLDGEVLSLKDLQQTAESSGLGPMAQPPSWPVGSTTETSGGPELSDSLSSGGIVAQAPLRKVKSRVRVRRASISEPSDTDPELRTLDPSPAGWFVQQHRELELLNSFRERFGCDWLQYRSHLETLGSPPLVTTKTLALSTSLLDAQSLETACSPPATGGAAEIKESPQKVSEESRVEPEPYEEEREERDKEEESREDLEEEEEQEQKEVEAELCRPMLVCPLQGLESVQGKECFLRVTSAHLFEVELRAARTLERLELQSLVAAELEPETEIQREQVPEGSGPPPGAPVLVLRFSYICPDRQLRRYAVLEPEAQEAIQELLAVLSPFTNSKEQQPGEAKDPRGARFQCLRCSCEFKPEEPRLGLENEEGWKPLFQNPESPVVCPNCGSDHVVLLAMSGEIPSREQSQGDKPPDPPGFPDPDCDLADHSGHPSGSDGTLPQASISNGHSSWSLSPTPGHSGLRSVDHRLRLFLDVEVFSDSEEEFQCCTKVPVALAGHMGEFLCLVVVSDRRLYLLKVTGAICGPPASWLQPTLAIPLQDLSGMELGLAGQSLRLEWAAGTGSCVLLPRDARHCRAFLEELTGVLQSLPRTQRNCISATEEEVTPQHRLWPLLGKETSAEVPQFFYLRTFLAEGSSTFPVSLLLTLSTLYLLDEDPAGSQAEFPLAVVSGEASEQTPPLGPGPSMQVREQQPLSSLSSVQLYRTSPLDLRLIFYDEVSRLESFWALRVVCGEQLTALLAWIREPWEELFSIGLRTVTQEALDLDR", "length": 1080, "header": "tr|A0A8C2MW73-1|A0A8C2MW73_CRIGR Isoform 1 of Serine/threonine-protein kinase 11-interacting protein OS=Cricetulus griseus OX=10029 GN=Stk11ip PE=3 SV=1 CANONICAL=A0A8C2MW73-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MW73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73/entry#A0A8C2MW73-1", "sequence": { "sequence": "MTTAPRDSVVWKLAGLLRESGDAVLSGCSTLSLLTATLQQLNRVFELYLGPWGPGQTGFVALPSHPADSPIILQLQFLFDVLQKTLSLKLVHTPGAGLPGPIKIFPFKSLRQLELRGVPIHSLRGLRSIYSQLESLICSRSIQALEELLSACGGDLCSALPWLALLSADFSYNALTNLDSSLRLLSALRFLNLSHNHIQDCKGFLMDLSELYHLDISYNHLHLVPRVGPSGAALGILILRANELRSLQGLEQLRNLRHLDVAYNLLEGHTELSPLWLLAELRKLYLEGNPLWFHPAHRANTAQYLSPQARDAAHGFLLDGEVLSLKDLQQTAESSGLGPMAQPPSWPVGSTTETSGGPELSDSLSSGGIVAQAPLRKVKSRVRVRRASISEPSDTDPELRTLDPSPAGWFVQQHRELELLNSFRERFGCDWLQYRSHLETLGSPPLVTTKTLALSTSLLDAQSLETACSPPATGGAAEIKESPQKVSEESRVEPEPYEEEREERDKEEESREDLEEEEEQEQKEVEAELCRPMLVCPLQGLESVQGKECFLRVTSAHLFEVELRAARTLERLELQSLVAAELEPETEIQREQVPEGSGPPPGAPVLVLRFSYICPDRQLRRYAVLEPEAQEAIQELLAVLSPFTNSKEQQPGEAKDPRGARFQCLRCSCEFKPEEPRLGLENEEGWKPLFQNPESPVVCPNCGSDHVVLLAMSGEIPSREQSQGDKPPDPPGFPDPDCDLADHSGHPSGSDGTLPQASISNGHSSWSLSPTPGHSGLRSVDHRLRLFLDVEVFSDSEEEFQCCTKVPVALAGHMGEFLCLVVVSDRRLYLLKVTGAICGPPASWLQPTLAIPLQDLSGMELGLAGQSLRLEWAAGTGSCVLLPRDARHCRAFLEELTGVLQSLPRTQRNCISATEEEVTPQHRLWPLLGKETSAEVPQFFYLRTFLAEGSSTFPVSLLLTLSTLYLLDEDPAGSQAEFPLAVVSGEASEQTPPLGPGPSMQVREQQPLSSLSSVQLYRTSPLDLRLIFYDEVSRLESFWALRVVCGEQLTALLAWIREPWEELFSIGLRTVTQEALDLDR", "length": 1080, "header": "tr|A0A8C2MW73-1|A0A8C2MW73_CRIGR Isoform 1 of Serine/threonine-protein kinase 11-interacting protein OS=Cricetulus griseus OX=10029 GN=Stk11ip PE=3 SV=1 CANONICAL=A0A8C2MW73-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F7M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73/entry#A0A9J7F7M8-1", "sequence": { "sequence": "MTTAPRDSVVWKLAGLLRESGDAVLSGCSTLSLLTATLQQLNRVFELYLGPWGPGQTGFVALPSHPADSPIILQLQFLFDVLQKTLSLKLVHTPGAGLPGPIKIFPFKSLRQLELRGVPIHSLRGLRSIYSQLESLICSRSIQALEELLSACGGDLCSALPWLALLSADFSYNALTNLDSSLRLLSALRFLNLSHNHIQDCKGFLMDLSELYHLDISYNHLHLVPRVGPSGAALGILILRANELRSLQGLEQLRNLRHLDVAYNLLEGHTELSPLWLLAELRKLYLEGNPLWFHPAHRANTAQYLSPQARDAAHGFLLDGEVLSLKDLQQTAESSGLGPMAQPPSWPVGSTTETSGGPELSDSLSSGGIVAQAPLRKVKSRVRVRRASISEPSDTDPELRTLDPSPAGWFVQQHRELELLNSFRERFGCDWLQYRSHLETLGSPPLVTTKTLALSTSLLDAQSLETACSPPATGGAAEIKESPQKVSEESRVEPEPYEEEREERDKEEESREDLEEEEEQEQKEVEAELCRPMLVCPLQGLESVQGKECFLRVTSAHLFEVELRAARTLERLELQSLVAAELEPETEIQREQGSGPPPGAPVLVLRFSYICPDRQLRRYAVLEPEAQEAIQELLAVLSPFTNSKEQQPGEAKDPRGARFQCLRCSCEFKPEEPRLGLENEEGWKPLFQNPESPVVCPNCGSDHVVLLAMSGEIPSREQSQGDKPPDPPGFPDPDCDLADHSGHPSGSDGTLPQASISNGHSSWSLSPTPGHSGLRSVDHRLRLFLDVEVFSDSEEEFQCCTKVPVALAGHMGEFLCLVVVSDRRLYLLKVTGAICGPPASWLQPTLAIPLQDLSGMELGLAGQSLRLEWAAGTGSCVLLPRDARHCRAFLEELTGVLQSLPRTQRNCISATEEEVTPQHRLWPLLGKETSAEVPQFFYLRTFLAEGSSTFPVSLLLTLSTLYLLDEDPAGSQAEFPLAVVSGEASEQTPPLGPGPSMQVREQQPLSSLSSVQLYRTSPLDLRLIFYDEVSRLESFWALRVVCGEQLTALLAWIREPWEELFSIGLRTVTQEALDLDR", "length": 1077, "header": "tr|A0A9J7F7M8-1|A0A8C2MW73_CRIGR Computationally mapped isoform of Serine/threonine-protein kinase 11-interacting protein OS=Cricetulus griseus OX=10029 GN=Stk11ip PE=3 SV=1 CANONICAL=A0A8C2MW73-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FC18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73/entry#A0A9J7FC18-1", "sequence": { "sequence": "MTTAPRDSVVWKLAGLLRESGDAVLSGCSTLSLLTATLQQLNRVFELYLGPWGPGQTGFVALPSHPADSPIILQLQFLFDVLQKTLSLKLVHTPGAGLPGPIKIFPFKSLRQLELRGVPIHSLRGLRSIYSQLESLICSRSIQALEELLSACGGDLCSALPWLALLSADFSYNALTNLDSSLRLLSALRFLNLSHNHIQDCKGFLMDLSELYHLDISYNHLHLVPRVGPSGAALGILILRANELRSLQGLEQLRNLRHLDVAYNLLEGHTELSPLWLLAELRKLYLEGNPLWFHPAHRANTAQYLSPQARDAAHGFLLDGEVLSLKDLQTAESSGLGPMAQPPSWPVGSTTETSGGPELSDSLSSGGIVAQAPLRKVKSRVRVRRASISEPSDTDPELRTLDPSPAGWFVQQHRELELLNSFRERFGCDWLQYRSHLETLGSPPLVTTKTLALSTSLLDAQSLETACSPPATGGAAEIKESPQKVSEESRVEPEPYEEEREERDKEEESREDLEEEEEQEQKEVEAELCRPMLVCPLQGLESVQGKECFLRVTSAHLFEVELRAARTLERLELQSLVAAELEPETEIQREQVPEGSGPPPGAPVLVLRFSYICPDRQLRRYAVLEPEAQEAIQELLAVLSPFTNSKEQQPGEAKDPRGARFQCLRCSCEFKPEEPRLGLENEEGWKPLFQNPESPVVCPNCGSDHVVLLAMSGEIPSREQSQGDKPPDPPGFPDPDCDLADHSGHPSGSDGTLPQASISNGHSSWSLSPTPGHSGLRSVDHRLRLFLDVEVFSDSEEEFQCCTKVPVALAGHMGEFLCLVVVSDRRLYLLKVTGAICGPPASWLQPTLAIPLQDLSGMELGLAGQSLRLEWAAGTGSCVLLPRDARHCRAFLEELTGVLQSLPRTQRNCISATEEEVTPQHRLWPLLGKETSAEVPQFFYLRTFLAEGSSTFPVSLLLTLSTLYLLDEDPAGSQAEFPLAVVSGEASEQTPPLGPGPSMQVREQQPLSSLSSVQLYRTSPLDLRLIFYDEVSRLESFWALRVVCGEQLTALLAWIREPWEELFSIGLRTVTQEALDLDR", "length": 1079, "header": "tr|A0A9J7FC18-1|A0A8C2MW73_CRIGR Computationally mapped isoform of Serine/threonine-protein kinase 11-interacting protein OS=Cricetulus griseus OX=10029 GN=Stk11ip PE=3 SV=1 CANONICAL=A0A8C2MW73-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 771, "start_aa": "Thr", "end_pos": 771, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr771", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F7M8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F7M8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F7M8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F7M8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767028", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767028", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW73", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW73", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW73", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW73", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MW73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73" }, { "id": "PF15904", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15904" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LKB1 serine/threonine kinase interacting protein 1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 94, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MW73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73" }, { "id": "PF23142", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23142" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PLEKHM2 PH", "eco_id": "ECO_0000259", "start_pos": 775, "end_pos": 915, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MW73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73" }, { "id": "PF25624", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25624" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "STK11-interacting protein C-terminal PH", "eco_id": "ECO_0000259", "start_pos": 918, "end_pos": 1073, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MW73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW73" }, { "id": "PF25357", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25357" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serine/threonine-protein kinase 11-interacting protein PH", "eco_id": "ECO_0000259", "start_pos": 524, "end_pos": 645, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 771 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MW90-1", "uniprot_ac": "A0A8C2MW90", "uniprot_id": "A0A8C2MW90_CRIGR", "mass": { "chemical_mass": 15792.0, "monoisotopic_mass": 15792.0 }, "refseq": { "ac": "XP_016831549", "name": "golgin subfamily A member 7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831549" }, "gene_names": [ { "name": "Golga7", "type": "recommended", "evidence": [ { "id": "A0A8C2MW90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW90" } ] }, { "name": "Golga7", "type": "synonym", "evidence": [ { "id": "XP_016831549", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831549" } ] } ], "protein_names": [ { "name": "Golgin subfamily A member 7", "type": "recommended", "evidence": [ { "id": "A0A8C2MW90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW90/entry#names_and_taxonomy" } ] }, { "name": "golgin subfamily A member 7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016831549", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831549" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613958.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016831549", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831549" } ] }, { "annotation": "May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F768", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F768#function" }, { "database": "UniProtKB", "id": "ARBA00037666", "url": "https://www.uniprot.org/uniprotkb/ARBA00037666#function" }, { "database": "UniProtKB", "id": "A0A8C2MW90", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW90#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MW90", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW90" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Golga7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW90", "locus": {} } ], "crossref": [ { "id": "100752519", "url": "https://www.ncbi.nlm.nih.gov/gene/100752519", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752519", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752519", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CEMRPQQ", "url": "https://omabrowser.org/oma/group/CEMRPQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MW90", "url": "https://www.orthodb.org/?gene=A0A8C2MW90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7F768", "url": "https://www.orthodb.org/?gene=A0A9J7F768", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13254:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13254:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016831549", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831549", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MW90", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MW90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F768", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F768", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F768-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F768-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPQQAPVSGKVFIQRDYSSGTRCQFQTKFPAELENRIDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKVSKYIQEQNEKIYAPQGLLLTDPIERGLRVIEITIYEDRGVSSGR", "length": 137, "header": "tr|A0A8C2MW90-1|A0A8C2MW90_CRIGR Isoform 1 of Golgin subfamily A member 7 OS=Cricetulus griseus OX=10029 GN=Golga7 PE=3 SV=1 CANONICAL=A0A8C2MW90-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MW90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW90/entry#A0A8C2MW90-1", "sequence": { "sequence": "MRPQQAPVSGKVFIQRDYSSGTRCQFQTKFPAELENRIDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKVSKYIQEQNEKIYAPQGLLLTDPIERGLRVIEITIYEDRGVSSGR", "length": 137, "header": "tr|A0A8C2MW90-1|A0A8C2MW90_CRIGR Isoform 1 of Golgin subfamily A member 7 OS=Cricetulus griseus OX=10029 GN=Golga7 PE=3 SV=1 CANONICAL=A0A8C2MW90-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F768-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW90/entry#A0A9J7F768-1", "sequence": { "sequence": "MRPQQAPVSGKVFIQRDYSSGTRCQFQTKFPAELENRIDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKVSKYIQEQNEKIYAPQGLLLTDPIERGLRVFRLKSPSMKTEV", "length": 134, "header": "tr|A0A9J7F768-1|A0A8C2MW90_CRIGR Computationally mapped isoform of Golgin subfamily A member 7 OS=Cricetulus griseus OX=10029 GN=Golga7 PE=3 SV=1 CANONICAL=A0A8C2MW90-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F768", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F768" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 428 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615072.1) and transcript sequence (JI877842.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007650031", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650031" } ] }, { "annotation": "May play a role in ubiquitination and subsequent proteasomal degradation of target proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWC2#function" }, { "database": "UniProtKB", "id": "ARBA00060190", "url": "https://www.uniprot.org/uniprotkb/ARBA00060190#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWC2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sugt1", "url": 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Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027258473", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258473" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWC6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWC6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ldlrad4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWC6", "locus": {} } ], "crossref": [ { "id": "cd00112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758578", "url": "https://www.ncbi.nlm.nih.gov/gene/100758578", "database": "GeneID", "categories": [ "Genome 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"categories": [ "Protein" ] }, { "id": "A0A9J7JUT1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUT1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEAGFQATNAFTECKFTCTSGKCLYLGSLVCNQQNDCGDNSDEENCLLVTEHPPPGIFNSELEFAQVLIIVVVVTVMVVVVVCLLNHYKVSTRSFINRPNQSRRQEDGLQPEGCLWPSDSSVQRPGASEIMCAPRGRDRFTTPSFIQRDPFSRFQPTYPYVQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTVFDSDLIDISMYNGGPCPPSSHSGISAATCSSNGRMEGPPPTYSEVMGHYPGTSFFHHQHSNAHRGSRPQFQPNNSEGTIVPIKGKDRKPGNLV", "length": 306, "header": "tr|A0A8C2MWC6-1|A0A8C2MWC6_CRIGR Isoform 1 of Low-density lipoprotein receptor class A domain-containing protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ldlrad4 PE=3 SV=1 CANONICAL=A0A8C2MWC6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MWC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWC6/entry#A0A8C2MWC6-1", 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}, { "name": "ATP-dependent RNA helicase DDX25 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027267590", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267590" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267590", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267590" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWH4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ddx25", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4", "locus": {} } ], "crossref": [ { "id": "cd18787", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18787", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759427", "url": "https://www.ncbi.nlm.nih.gov/gene/100759427", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759427", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759427", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DFKNLCM", "url": "https://omabrowser.org/oma/group/DFKNLCM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MWH4", "url": "https://www.orthodb.org/?gene=A0A8C2MWH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027267590", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267590", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MWH4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MWH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWT6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWT6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLLWGGDAGAAESERLNSHFSNLVHPRKNLRGIRSTTVPNIDGSLNTEEDDDEDDVVDLAANSLLNKLIRQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVERMGKFCVDVEVMYAIRGNRIPRGTEVTKQIIIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFSDQSIRIQRALPSECQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCENRKDKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQSEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDKLPLLMKIQDHFNSNIKQLDPEDMDEIEKIEY", "length": 483, "header": "tr|A0A8C2MWH4-1|A0A8C2MWH4_CRIGR Isoform 1 of RNA helicase OS=Cricetulus griseus OX=10029 GN=Ddx25 PE=4 SV=1 CANONICAL=A0A8C2MWH4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MWH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4/entry#A0A8C2MWH4-1", "sequence": { "sequence": "MASLLWGGDAGAAESERLNSHFSNLVHPRKNLRGIRSTTVPNIDGSLNTEEDDDEDDVVDLAANSLLNKLIRQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVERMGKFCVDVEVMYAIRGNRIPRGTEVTKQIIIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFSDQSIRIQRALPSECQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCENRKDKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQSEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDKLPLLMKIQDHFNSNIKQLDPEDMDEIEKIEY", "length": 483, "header": "tr|A0A8C2MWH4-1|A0A8C2MWH4_CRIGR Isoform 1 of RNA helicase OS=Cricetulus griseus OX=10029 GN=Ddx25 PE=4 SV=1 CANONICAL=A0A8C2MWH4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GWT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4/entry#A0A9J7GWT6-1", "sequence": { "sequence": "MGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVERMGKFCVDVEVMYAIRGNRIPRGTEVTKQIIIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFSDQSIRIQRALPSECQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCENRKDKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQSEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDKLPLLMKIQDHFNSNIKQLDPEDMDEIEKIEY", "length": 369, "header": "tr|A0A9J7GWT6-1|A0A9J7GWT6_CRIGR Computationally mapped isoform of RNA helicase OS=Cricetulus griseus OX=10029 GN=Ddx25 PE=4 SV=1 CANONICAL=A0A8C2MWH4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWH4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWH4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759427", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759427", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MSI6-1", "protein_name": "RNA helicase", "gene_name": "DDX25", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASLLWGGDAGAAESERLNGHFSNLIHPQNHLLGIKSATIPNIDGSVNRIEEDDEDDVVDLAANSLLNKLIRQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALKLFPQCLCLAPTYELALQTGRVVERMGKFCVDVQVMYAIRGNRIPRGTDVTKQIVIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFADQSIRIQRALPSECQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCGNRKDKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVDQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQAEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDKLPLLMKIQDHFNSSIKQLDPEDMDEIEKIEY", "length": 483 }, "evidence": [ { "id": "A0A8C2MWH4", "url": "https://omabrowser.org/oma/group/A0A8C2MWH4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S758-1", "protein_name": "RNA helicase", "gene_name": "DDX25", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASLLWGGDAGAAESERLNRHFSNLIHPPKNLRGIKNTTVPNVDGSVNNTEEDDEEDVVDLAANSLLNKLIRQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVERMGRFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFSDQSIRIQRALPSGCQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCGNRKDKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVDQRAAIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQAEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDKLPLLMKIQDHFNSNIKQLDPEDMDEIEKIEY", "length": 483 }, "evidence": [ { "id": "A0A8C2MWH4", "url": "https://omabrowser.org/oma/group/A0A8C2MWH4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q54TF8-1", "protein_name": "ATP-dependent RNA helicase ddx19", "gene_name": "helC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSEKETNTTSTENKEKEKQEQTNTNSTTESTNNQVDEEYERPGRSEGLDEFGIQLDIQQSDPNSPLYSVKTFEELGLKPELLKGVYAMGYNKPSKIQEAALPIIIQSPNNLIAQSQSGTGKTAAFTLGMLNCVDPSINAPQAICISPTKELALQTFEVISKIGQFSNIKPLLYISEIEVPKNVTNQVIIGTPGKILENVIKKQLSVKFLKMVVLDEADFIVKMKNVPNQIAMINRLLPSNVKVCLFSATFSMGVEELIKKIVQDPYTSIRLKRQELSVEKIHQYFIDCGSEDNKALILSDIYGFISVGQSIVFVHTIATAKSVHQKMVDEGHSVSLLYGKDLTTEERFKQIKDFKDGKSKVLITTNVLARGIDIPQVSLVINYDVPLDEMGKPDPVHYLHRIGRVGRFGRSGVALSFVYDQQSTNKLMNISTHLGVPLKELKSSEIESLDGILKGIRNQLTPLNN", "length": 465 }, "evidence": [ { "id": "A0A8C2MWH4", "url": "https://omabrowser.org/oma/group/A0A8C2MWH4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q93ZG7-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 38", "gene_name": "RH38", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADTVEKVPTVVESSSSSTVEASNSAEKTEPTTEKKKWGDVEDDDDEEEAVSELNSLSIKEEEKPDSILEEPEDSNIKAVTSGDTPYTSASRFEDLNLSPELMKGLYVEMKFEKPSKIQAISLPMIMTPPHKHLIAQAHNGSGKTTCFVLGMLSRVDPTLREPQALCICPTRELANQNMEVLQKMGKFTGITAELAVPDSTRGAPAATRGAPVSAHVVIGTPGTLKKWMAFKRLGLNHLKILVFDEADHMLATDGFRDDSLKIMKDIGRVNPNFQVLLFSATFNETVKDFVARTVKDPNQLFVKREDLALDSVKQYKVVCPKEQNKIEVIKDQIMELGDIGQTIIFVKTKASAQKVHKALAEMGYDVTSVHGNLTESDRDKIVKEFKECLTQVLIATDVIARGFDQQRVNLVVNYNLPTKYETGEPDYEVYLHRVGRAGRFGRKGAVFNLLLDDGWDKEVMEKIEKYFEANVKEIKSWNSEEEYKSALKEAGLLDE", "length": 496 }, "evidence": [ { "id": "A0A8C2MWH4", "url": "https://omabrowser.org/oma/group/A0A8C2MWH4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9QY15-1", "protein_name": "ATP-dependent RNA helicase DDX25", "gene_name": "Ddx25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLLWGGDAGAAESERLNSHFSNLVHPRKNLRGIRSTTVPNIDGSLNTEDDDDDEDDVVDLAANSLLNKLIRQSLIESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVERMGKFCVDVEVMYAIRGNRIPRGTEVTKQIIIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFSDQSIRIQRALPSECQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCENRKGKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQSEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDKLPLLMKIQDHFNSNIKQLDPEDMDEIEKIEY", "length": 484 }, "evidence": [ { "id": "A0A8C2MWH4", "url": "https://omabrowser.org/oma/group/A0A8C2MWH4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QY16-1", "protein_name": "ATP-dependent RNA helicase DDX25", "gene_name": "Ddx25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASLLWGGDAGAAESERLNSHFSNLVHPRKNLRGIRSTTVPNIDGSLNTEEDDDEDDVVDLAANSLLNKLIRQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLNRVNALELFPQCLCLAPTYELALQTGRVVERMGKFCVDVEVMYAIRGNRIPRGTDVTKQIVIGTPGTVLDWCFKRKLIDLTKIRVFVLDEADVMIDTQGFSDQSIRIQRALPSECQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYVLCENRKDKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQSEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDKLPLLMKIQDHFNSSIKQLDPEDMDEIEKIEY", "length": 483 }, "evidence": [ { "id": "A0A8C2MWH4", "url": "https://omabrowser.org/oma/group/A0A8C2MWH4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UHL0-1", "protein_name": "ATP-dependent RNA helicase DDX25", "gene_name": "DDX25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASLLWGGDAGAAESERLNSHFSNLSQPRKNLWGIKSTAVRNIDGSINNINEDDEEDVVDLAANSLLNKLIHQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELPSLMKIQDHFNSSIKQLNAEDMDEIEKIDY", "length": 483 }, "evidence": [ { "id": "A0A8C2MWH4", "url": "https://omabrowser.org/oma/group/A0A8C2MWH4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWH4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWH4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWH4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWH4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWH4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWH4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ], "pmid": "" }, { "name": "chromatoid body", "id": "GO:0033391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033391", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWH4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWH4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWH4", "url": 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}, { "uniprot_ac": "A0A8C2MCA5", "gene_name": "Ddx41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MCA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCA5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MCA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCA5" } ] } ] }, { "uniprot_ac": "A0A8C2MCS3", "gene_name": "Ddx47", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MCS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCS3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MCS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCS3" } ] } ] }, { "uniprot_ac": "A0A8C2MFM1", "gene_name": "Vps4b", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFM1" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8C2MFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFM1" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MPK3", "gene_name": "Mcm6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MPK3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8C2MPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MPK3" } ] } ] }, { "uniprot_ac": "A0A8C2MQ86", "gene_name": "Ddx50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MQ86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ86" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MQ86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ86" } ] } ] }, { "uniprot_ac": "A0A8C2MVH8", "gene_name": "Mcm7", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MVH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVH8" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8C2MVH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVH8" } ] } ] }, { "uniprot_ac": "A0A8C2MWE0", "gene_name": "Snrnp200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWE0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWE0" } ] } ] }, { "uniprot_ac": "A0A8C2MWH4", "gene_name": "Ddx25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MWH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MWH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ] } ] }, { "uniprot_ac": "A0A8C2MYM8", "gene_name": "Tdrd9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYM8" } ] } ] }, { "uniprot_ac": "A0A8C2N055", "gene_name": "Ythdc2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2N055", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N055" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2N055", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N055" } ] } ] }, { "uniprot_ac": "A0A8C2N184", "gene_name": "Entpd8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8C2N184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N184" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8C2N184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N184" } ] } ] }, { "uniprot_ac": "A0A8C2N236", "gene_name": "Atp13a4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8C2N236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N236" } ] } ] }, { "uniprot_ac": "A0A8C2N386", "gene_name": "Vcp", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2N386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N386" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8C2N386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N386" } ] } ] }, { "uniprot_ac": "A0A8C2QH91", "gene_name": "Ino80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8C2QH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH91" } ] } ] }, { "uniprot_ac": "A0A8C2QHV1", "gene_name": "Ddx20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] } ] }, { "uniprot_ac": "A0A8C2QLX9", "gene_name": "Ddx52", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QLX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLX9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QLX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLX9" } ] } ] }, { "uniprot_ac": "A0A8C2QM19", "gene_name": "Clpx", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QM19" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8C2QM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QM19" } ] } ] }, { "uniprot_ac": "A0A8C2QNE7", "gene_name": "Eif4a3", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNE7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNE7" } ] } ] }, { "uniprot_ac": "A0A9J7F1E5", "gene_name": "Hltf", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A9J7F1E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A9J7F1E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E5" } ] } ] }, { "uniprot_ac": "A0A9J7F876", "gene_name": "Ddx11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7F876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F876" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7F876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F876" } ] } ] }, { "uniprot_ac": "A0A9J7F9W3", "gene_name": "Zgrf1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7F9W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9W3" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7F9W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9W3" } ] } ] }, { "uniprot_ac": "A0A9J7FCH5", "gene_name": "Mov10l1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCH5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCH5" } ] } ] }, { "uniprot_ac": "A0A9J7FI19", "gene_name": "Xrcc6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] } ] }, { "uniprot_ac": "A0A9J7FI42", "gene_name": "Fbh1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI42" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI42" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FJ37", "gene_name": "Mcm9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ37" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ37" } ] } ] }, { "uniprot_ac": "A0A9J7FPD0", "gene_name": "Dhx32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FPD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FPD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPD0" } ] } ] }, { "uniprot_ac": "A0A9J7FPK3", "gene_name": "Twnk", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7FPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPK3" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7FPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPK3" } ] } ] }, { "uniprot_ac": "A0A9J7FTT2", "gene_name": "Mcm5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": 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"id": "A0A9J7FYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYM8" } ] } ] }, { "uniprot_ac": "A0A9J7G1N4", "gene_name": "Fancm", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G1N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1N4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G1N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1N4" } ] } ] }, { "uniprot_ac": "A0A9J7G2T1", "gene_name": "Dhx9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G2T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G2T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T1" } ] } ] }, { "uniprot_ac": "A0A9J7G412", "gene_name": "Helz2", "activity": [ { "ec_number": "3.1.13.1", "activity": "Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] }, { "ec_number": "3.1.13.1", "activity": "", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] } ] }, { "uniprot_ac": "A0A9J7G5W9", "gene_name": "Spata5l1", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A9J7G5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W9" } ] } ] }, { "uniprot_ac": "A0A9J7G659", "gene_name": "Rtel1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A0A9J7G659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G659" } ] } ] }, { "uniprot_ac": "A0A9J7G6M1", "gene_name": "Mcm8", "activity": [ { "ec_number": "2.7.8.41", "activity": "a CDP-1,2-diacyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + CMP + H(+).", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M1" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": 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[ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GN75" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7GN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GN75" } ] } ] }, { "uniprot_ac": "A0A9J7GR00", "gene_name": "Entpd1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A9J7GR00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR00" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A9J7GR00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR00" } ] } ] }, { "uniprot_ac": "A0A9J7GRQ0", "gene_name": "Ak6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 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Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 1972 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617646.1) and transcript sequence (JP042830.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003515306.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003515306", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515306" } ] }, { "annotation": "Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. 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"MITSAAGIISLLDEEEPQLKEFALHKLNAVVNDFWAEISESVDKIEVLYEDEGFRSRQFAALVASKVFYHLGAFEESLNYALGAGDLFNVNDNSEYVETIIAKCIDHYTKQCVENADLPEGEKKPIDQRLEGIVNKMFQRCLDDHKYKQAIGIALETRRLDVFEKTILESNDVPGMLAYSLKLCMSLMQNKQFRNKVLRVLVKIYMNLEKPDFINVCQCLIFLDDPQAVSDILEKLVKEDNLLMAYQICFDLYESASQQFLSSVIQNLRTVGTPIASVPGSTNTGTVPGSEKDSDPMETEEKTGNTPVGKTPDVSPEPKDQTLKMIKILSGEMAIELHLQFLIRNNNTDLMILKNTKDAVRNSVCHTATVIANSFMHCGTTSDQFLRDNLEWLARATNWAKFTATASLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLLNQLKNASNDIVRHGGSLGLGLAAMGTARQDVYDLLKTNLYQDDAVTGEAAGLALGLVMLGSKNAQAIEDMVGYAQETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNNKAIRRLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMALGICCAGTGNKEAINLLEPMTNDPVNYVRQGALIASALIMIQQTEITCPKVNQFRQLYSKVINDKHDDVMAKFGAILAQGILDAGGHNVTISLQSRTGHTHMPSVVGVLVFTQFWFWFPLSHFLSLAYTPTCVIGLNKDLKMPKVQYKSNCKPSTFAYPAPLEVPKEKEKEKVSTAVLSITAKAKKKEKEKEKKEEEKMEVDEAEKKEEKEKKKEPEPNFQLLDNPARVMPAQLKVLTMTETCRYQPFKPLSIGGIIILKDTSEDIEELVEPVAAHGPKIEEEEQEPEPPEPFEYIDD", "length": 953, "header": "tr|A0A8C2MWM2-1|A0A8C2MWM2_CRIGR Isoform 1 of 26S proteasome non-ATPase regulatory subunit 1 OS=Cricetulus griseus OX=10029 GN=LOC100760261 PE=3 SV=1 CANONICAL=A0A8C2MWM2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MWM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWM2/entry#A0A8C2MWM2-1", "sequence": { "sequence": "MITSAAGIISLLDEEEPQLKEFALHKLNAVVNDFWAEISESVDKIEVLYEDEGFRSRQFAALVASKVFYHLGAFEESLNYALGAGDLFNVNDNSEYVETIIAKCIDHYTKQCVENADLPEGEKKPIDQRLEGIVNKMFQRCLDDHKYKQAIGIALETRRLDVFEKTILESNDVPGMLAYSLKLCMSLMQNKQFRNKVLRVLVKIYMNLEKPDFINVCQCLIFLDDPQAVSDILEKLVKEDNLLMAYQICFDLYESASQQFLSSVIQNLRTVGTPIASVPGSTNTGTVPGSEKDSDPMETEEKTGNTPVGKTPDVSPEPKDQTLKMIKILSGEMAIELHLQFLIRNNNTDLMILKNTKDAVRNSVCHTATVIANSFMHCGTTSDQFLRDNLEWLARATNWAKFTATASLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLLNQLKNASNDIVRHGGSLGLGLAAMGTARQDVYDLLKTNLYQDDAVTGEAAGLALGLVMLGSKNAQAIEDMVGYAQETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNNKAIRRLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMALGICCAGTGNKEAINLLEPMTNDPVNYVRQGALIASALIMIQQTEITCPKVNQFRQLYSKVINDKHDDVMAKFGAILAQGILDAGGHNVTISLQSRTGHTHMPSVVGVLVFTQFWFWFPLSHFLSLAYTPTCVIGLNKDLKMPKVQYKSNCKPSTFAYPAPLEVPKEKEKEKVSTAVLSITAKAKKKEKEKEKKEEEKMEVDEAEKKEEKEKKKEPEPNFQLLDNPARVMPAQLKVLTMTETCRYQPFKPLSIGGIIILKDTSEDIEELVEPVAAHGPKIEEEEQEPEPPEPFEYIDD", "length": 953, "header": "tr|A0A8C2MWM2-1|A0A8C2MWM2_CRIGR Isoform 1 of 26S proteasome non-ATPase regulatory subunit 1 OS=Cricetulus griseus OX=10029 GN=LOC100760261 PE=3 SV=1 CANONICAL=A0A8C2MWM2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWM2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWM2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760261", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760261", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "proteasome storage granule", "id": "GO:0034515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034515", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWM2" } ], "pmid": "" }, { "name": "proteasome regulatory particle, base subcomplex", "id": "GO:0008540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008540", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWM2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWM2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWM2" } ], "pmid": "" }, { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWM2" } ], "pmid": "" }, { "name": "regulation of protein catabolic process", "id": "GO:0042176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042176", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" }, { "start_pos": 743, "end_pos": 745, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MWP2-1", "uniprot_ac": "A0A8C2MWP2", "uniprot_id": "A0A8C2MWP2_CRIGR", "mass": { "chemical_mass": 108609.0, "monoisotopic_mass": 108609.0 }, "refseq": { "ac": "XP_027283507", "name": "meiosis-specific coiled-coil domain-containing protein MEIOC isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283507" }, "gene_names": [ { "name": "Meioc", "type": "recommended", "evidence": [ { "id": "A0A8C2MWP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2" } ] }, { "name": "Meioc", "type": "synonym", "evidence": [ { "id": "XP_027283507", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283507" } ] } ], "protein_names": [ { "name": "Meiosis-specific coiled-coil domain-containing protein MEIOC isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2MWP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2/entry#names_and_taxonomy" } ] }, { "name": "meiosis-specific coiled-coil domain-containing protein MEIOC isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027283507", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283507" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283507", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283507" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Meioc", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2", "locus": {} } ], "crossref": [ { "id": "100763401", "url": "https://www.ncbi.nlm.nih.gov/gene/100763401", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763401", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763401", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MWP2", "url": "https://www.orthodb.org/?gene=A0A8C2MWP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33861", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33861", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33861:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33861:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15189", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15189", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027283507", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283507", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MWP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MWP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVSGGDTCRPRHPQGLREGPEPKVAFRGSANRCWNLSVDTSSRLSDVFNSMMLTGSTSFYDCYKAQNEDNVDLRQTCTPLSSSTEYASPLDSSLFYAPWSTYGDDVKQPSSSQISVKNRIQTERNDYGSETDLYGLVSNILEEQDKSQPYFAEGTCSSNLKSVWPMNTSRFVDHHDLLTETKRPIDTTISQQAFYSGESVSAVEKQYLHNNNLTPQQKIDELYHGYTGLDLEEQWLYLSRSDHSNCYNIQTNDTVKATFQEYPFIKNCFTPQTGLSDIMKESGIDTYSYGREKICAKGLETPLQHKRAEIFLSQFNRYNENADYCRYPEYAHPNKAKLNKCSNFSVQDGKKLANGTPETPAVEADAYTKLFQVKPANQKKMEETIPDQQNFAFQKTTPHLTEKQFAKEAAFTADFGLKSEYGLKPHTACPANNDFANVTEKQQFAKPDPLNSEYFKSVNLFSNAATSSGGISLNRPTWMNVQTKNNLPIPYRNQGNLMKLNSHLTAASKGSNHSSDFPQLSSTNITSNSNLFQKYCQENPSAFSSFDFSYNGAERIQSVNHMEGLTKTGEDNLFESVTEKKIKQQNGFCDSYSASQYGIIENVNKHNFQAKPQSGHYDPEDIPKHFDGLPQNTYQDLLESQGHFNSHRQGSGDSNINSRVNRTQASCFSNNYMMGDLRHNQGFQQLGSNGFPLRSTHPFGHSVVPLLDSYDLFSYDDLSHLYPYFNDMMYGDNSFSGFVPTFGFQRPIKTRSGPASELHIRLEECYEQWRALEKERKKTELALAKNYPGKKVSSTNNTPIPRLTSNPSRVDRLIVDELREQARVVTLLGKMERLRSSPLHANISTALDRHLESIHIVQSRRKDEIVNASNRQRQGVPRCQDDRDVFALATAIKEMCVATRKARTTLWCALQMTLPKTASTSGQADMEKAFQELVNCEDKVHESINSSNPMNQRGETNKH", "length": 960, "header": "tr|A0A8C2MWP2-1|A0A8C2MWP2_CRIGR Isoform 1 of Meiosis-specific coiled-coil domain-containing protein MEIOC isoform X2 OS=Cricetulus griseus OX=10029 GN=Meioc PE=4 SV=1 CANONICAL=A0A8C2MWP2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MWP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2/entry#A0A8C2MWP2-1", "sequence": { "sequence": "MEVSGGDTCRPRHPQGLREGPEPKVAFRGSANRCWNLSVDTSSRLSDVFNSMMLTGSTSFYDCYKAQNEDNVDLRQTCTPLSSSTEYASPLDSSLFYAPWSTYGDDVKQPSSSQISVKNRIQTERNDYGSETDLYGLVSNILEEQDKSQPYFAEGTCSSNLKSVWPMNTSRFVDHHDLLTETKRPIDTTISQQAFYSGESVSAVEKQYLHNNNLTPQQKIDELYHGYTGLDLEEQWLYLSRSDHSNCYNIQTNDTVKATFQEYPFIKNCFTPQTGLSDIMKESGIDTYSYGREKICAKGLETPLQHKRAEIFLSQFNRYNENADYCRYPEYAHPNKAKLNKCSNFSVQDGKKLANGTPETPAVEADAYTKLFQVKPANQKKMEETIPDQQNFAFQKTTPHLTEKQFAKEAAFTADFGLKSEYGLKPHTACPANNDFANVTEKQQFAKPDPLNSEYFKSVNLFSNAATSSGGISLNRPTWMNVQTKNNLPIPYRNQGNLMKLNSHLTAASKGSNHSSDFPQLSSTNITSNSNLFQKYCQENPSAFSSFDFSYNGAERIQSVNHMEGLTKTGEDNLFESVTEKKIKQQNGFCDSYSASQYGIIENVNKHNFQAKPQSGHYDPEDIPKHFDGLPQNTYQDLLESQGHFNSHRQGSGDSNINSRVNRTQASCFSNNYMMGDLRHNQGFQQLGSNGFPLRSTHPFGHSVVPLLDSYDLFSYDDLSHLYPYFNDMMYGDNSFSGFVPTFGFQRPIKTRSGPASELHIRLEECYEQWRALEKERKKTELALAKNYPGKKVSSTNNTPIPRLTSNPSRVDRLIVDELREQARVVTLLGKMERLRSSPLHANISTALDRHLESIHIVQSRRKDEIVNASNRQRQGVPRCQDDRDVFALATAIKEMCVATRKARTTLWCALQMTLPKTASTSGQADMEKAFQELVNCEDKVHESINSSNPMNQRGETNKH", "length": 960, "header": "tr|A0A8C2MWP2-1|A0A8C2MWP2_CRIGR Isoform 1 of Meiosis-specific coiled-coil domain-containing protein MEIOC isoform X2 OS=Cricetulus griseus OX=10029 GN=Meioc PE=4 SV=1 CANONICAL=A0A8C2MWP2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763401", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763401", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "metaphase chromosome alignment", "id": "GO:0051310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051310", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2" } ], "pmid": "" }, { "name": "female meiosis I", "id": "GO:0007144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007144", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2" } ], "pmid": "" }, { "name": "synaptonemal complex assembly", "id": "GO:0007130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007130", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2" } ], "pmid": "" }, { "name": "oocyte development", "id": "GO:0048599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048599", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2" } ], "pmid": "" }, { "name": "male meiosis I", "id": "GO:0007141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007141", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2" } ], "pmid": "" }, { "name": "germline cell cycle switching, mitotic to meiotic cell cycle", "id": "GO:0051729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051729", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": 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:: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613657.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035297926", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297926" } ] }, { "annotation": "Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWQ1#function" }, { "database": "UniProtKB", "id": "ARBA00057254", "url": "https://www.uniprot.org/uniprotkb/ARBA00057254#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWQ1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cpne4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWQ1", "locus": {} } ], "crossref": [ { "id": "cd01459", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01459", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04047", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04047", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04048", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04048", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100763931", "url": "https://www.ncbi.nlm.nih.gov/gene/100763931", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763931", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763931", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XVIAEEL", "url": "https://omabrowser.org/oma/group/XVIAEEL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MWQ1", "url": "https://www.orthodb.org/?gene=A0A8C2MWQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10857", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10857", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10857:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10857:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035297926", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297926", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MWQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MWQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGMVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEVYESSRTLAP", "length": 557, "header": "tr|A0A8C2MWQ1-1|A0A8C2MWQ1_CRIGR Isoform 1 of Copine-4 OS=Cricetulus griseus OX=10029 GN=Cpne4 PE=3 SV=1 CANONICAL=A0A8C2MWQ1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MWQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWQ1/entry#A0A8C2MWQ1-1", "sequence": { "sequence": "MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGMVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEVYESSRTLAP", "length": 557, "header": "tr|A0A8C2MWQ1-1|A0A8C2MWQ1_CRIGR Isoform 1 of Copine-4 OS=Cricetulus griseus OX=10029 GN=Cpne4 PE=3 SV=1 CANONICAL=A0A8C2MWQ1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWQ1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWQ1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763931", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763931", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PNI0-1", "protein_name": "Copine-4", "gene_name": "CPNE4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVFSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELSFSARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLNPAWKTFKVSVNSLCSGDQDRRLKCIVWDWDSNGKHDFIGEFSSTFKEMRGAMEGRQVQWECINPKYKAKKKSYKNSGIVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYKVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCVSEYESSRTLAP", "length": 556 }, "evidence": [ { "id": "A0A8C2MWQ1", "url": "https://omabrowser.org/oma/group/A0A8C2MWQ1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LVU1-1", "protein_name": "Copine-4", "gene_name": "Cpne4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVEPSNPESMKKRVGRRMKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGMVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEVYESSRTLAP", "length": 575 }, "evidence": [ { "id": "A0A8C2MWQ1", "url": "https://omabrowser.org/oma/group/A0A8C2MWQ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9QJ75-1", "protein_name": "Copine-4", "gene_name": "cpne4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSNIYESAATTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVVLKMQSHGQWFEVDRTEVIRSSISPVFSKVFTVDYYFEEVQRLRFELHDISSNHNGLKEADFLGAMECTLGQIVSQRKLSKALLKQGNTAGKSSITVTAEELSGNDDYVELAFSAKKLDDKDFFSKSDPFLEIFRVNDDGTASLVHRTETIMNNLSPVWKSFKVSLNTLCSGDHDRELKCIVWDWDSNGKHDFIGEFQTTFKEMKSAMDGKQIQWECINPKYQVKKKNYRNSGMVILTLCKIIKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALIAVGEICQDYDSDKMFPAFGFGAQIPPDFKVSHDFAVNFDEDNPECAGVQGVIEAYQNCLPKIQLYGPTNIAPIIQKVANSASEEMHTKEAMEYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGIGSADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKGLSDYESSRAFSP", "length": 553 }, "evidence": [ { "id": "A0A8C2MWQ1", "url": "https://omabrowser.org/oma/group/A0A8C2MWQ1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q54P51-1", "protein_name": "Copine-C", "gene_name": "cpnC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIPSSKPNSRVELRFRCHHLKNLDIVSKSDPQIFISEKRGPGGFQFVDCTEKIKNNLSPEFKKTITLDYYFEEIQTLTFTVMDIDKEITLFGDLDKNDKIGEFTTSLSNILSRPGRKIVADLIHHSKVTGKIEISAEEICQTNHHIFLSAEGIGLDKKDLFSSDPYYKIYKTNPNGEQLLVFQSIVIKSNVNPLWPELHMELEKFNGGDMFRELLIEVYDYDSIGAHDLIGITRTTTDAILRGVIEYPLINPKKTSKSGYKNSGILKFYKVRLEKTHTFLEFLAGGCEISLMTAIDCTGSNGSVNSFSGLHYNDLEKGGSAYARSIASVGSVLSSYDSDGFIDVFGFGGEYQGRTSHCFPFSLDPNVPSAFGVAGVLEMYNRNISKIPFSGPTNFASVIQEAIARASESRLPYQQKYTVLLIITDGEICDMDETIKCLVQASNLPLSVVIVGVGLSSFENMNLLDGDNGCLVDYKGNRAKRDIVQFVPFNKYSGNINALAQETLKEIPGQLLSYFKSIGVPPNPPRTFIPVDILPPPPQ", "length": 539 }, "evidence": [ { "id": "A0A8C2MWQ1", "url": "https://omabrowser.org/oma/group/A0A8C2MWQ1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BLR2-1", "protein_name": "Copine-4", "gene_name": "Cpne4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGMVILNQCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEVYESSRTLAP", "length": 557 }, "evidence": [ { "id": "A0A8C2MWQ1", "url": "https://omabrowser.org/oma/group/A0A8C2MWQ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96A23-1", "protein_name": "Copine-4", "gene_name": "CPNE4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSLLKHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP", "length": 557 }, "evidence": [ { "id": "A0A8C2MWQ1", "url": "https://omabrowser.org/oma/group/A0A8C2MWQ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWQ1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWQ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWQ1" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWQ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWQ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MWQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWQ1" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 131, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 202, "end_pos": 204 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MWR2-1", "uniprot_ac": "A0A8C2MWR2", "uniprot_id": "A0A8C2MWR2_CRIGR", "mass": { "chemical_mass": 47326.0, "monoisotopic_mass": 47326.0 }, "refseq": { "ac": "XP_003507654", "name": "mitochondrial chaperone BCS1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507654" }, "gene_names": [ { "name": "LOC100771607", "type": "recommended", "evidence": [ { "id": "A0A8C2MWR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2" } ] }, { "name": "LOC100771607", "type": "synonym", "evidence": [ { "id": "XP_003507654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507654" } ] } ], "protein_names": [ { "name": "Mitochondrial chaperone BCS1", "type": "recommended", "evidence": [ { "id": "A0A8C2MWR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2/entry#names_and_taxonomy" } ] }, { "name": "BCS1-like protein", "type": "synonym", "evidence": [ { "id": "A0A8C2MWR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial chaperone BCS1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003507654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507654" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614410.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003507654", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507654" } ] }, { "annotation": "Chaperone necessary for the incorporation of Rieske iron-sulfur protein UQCRFS1 into the mitochondrial respiratory chain complex III. Plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K482", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K482#function" }, { "database": "UniProtKB", "id": "ARBA00058285", "url": "https://www.uniprot.org/uniprotkb/ARBA00058285#function" }, { "database": "UniProtKB", "id": "A0A8C2MWR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2#function" }, { "database": "UniProtKB", "id": "A0A9J7JE31", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JE31#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100771607", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2", "locus": {} } ], "crossref": [ { "id": "cd19510", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19510", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771607", "url": "https://www.ncbi.nlm.nih.gov/gene/100771607", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771607", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771607", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WMTLYQR", "url": "https://omabrowser.org/oma/group/WMTLYQR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MWR2", "url": "https://www.orthodb.org/?gene=A0A8C2MWR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08740", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08740", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25426", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25426", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003507654", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507654", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MWR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MWR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JE31", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JE31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JE31-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JE31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K482", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K482", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K482-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K482-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFTDFVLALKDNPYFGAGFGLVGVGTVLAAARKGAQLGLVAFRRHYMITLEVPARDRSYAWLLSWLTRHSTRTQHLSVETSYLQHESGRISTKFEFIPSPGNHFIWYQGKWIRVQRNRDMQMVDLQTGTPWESVIFTALGTDRKVFFNILEEARALALQQEEGKTVMYTAVGSEWRTFGYPRRRRPLDSVVLQQGLADRIVKDIREFIDNPKWYIDRGIPYRRGYLLYGPPGCGKSSFITALAGEVEHSICLLSLTDSSLSDDRLNHLLSVAPQQSLVLLEDVDAAFLSRDLAVENPVKYQGLGRLTFSGLLNALDGVASTEARIVFMTTNHIDRLDPALIRPGRVDMKEYVGYCSHWQLTQMFKRFYPGQAPSLAENFAEHVLKATSQISPAQVQGYFMLYKNDPMGAVDNVESLR", "length": 418, "header": "tr|A0A8C2MWR2-1|A0A8C2MWR2_CRIGR Isoform 1 of Mitochondrial chaperone BCS1 OS=Cricetulus griseus OX=10029 GN=LOC100771607 PE=3 SV=1 CANONICAL=A0A8C2MWR2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MWR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2/entry#A0A8C2MWR2-1", "sequence": { "sequence": "MPFTDFVLALKDNPYFGAGFGLVGVGTVLAAARKGAQLGLVAFRRHYMITLEVPARDRSYAWLLSWLTRHSTRTQHLSVETSYLQHESGRISTKFEFIPSPGNHFIWYQGKWIRVQRNRDMQMVDLQTGTPWESVIFTALGTDRKVFFNILEEARALALQQEEGKTVMYTAVGSEWRTFGYPRRRRPLDSVVLQQGLADRIVKDIREFIDNPKWYIDRGIPYRRGYLLYGPPGCGKSSFITALAGEVEHSICLLSLTDSSLSDDRLNHLLSVAPQQSLVLLEDVDAAFLSRDLAVENPVKYQGLGRLTFSGLLNALDGVASTEARIVFMTTNHIDRLDPALIRPGRVDMKEYVGYCSHWQLTQMFKRFYPGQAPSLAENFAEHVLKATSQISPAQVQGYFMLYKNDPMGAVDNVESLR", "length": 418, "header": "tr|A0A8C2MWR2-1|A0A8C2MWR2_CRIGR Isoform 1 of Mitochondrial chaperone BCS1 OS=Cricetulus griseus OX=10029 GN=LOC100771607 PE=3 SV=1 CANONICAL=A0A8C2MWR2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JE31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2/entry#A0A9J7JE31-1", "sequence": { "sequence": "MPFTDFVLALKDNPYFGAGFGLVGVGTVLAAARKGAQLGLVAFRRHYMITLEVPARDRSYAWLLSWLTRHSTRTQHLSVETSYLQHESGRISTKFEFIPSPGNHFIWYQGKWIRVQRNRDMQMVDLQTGTPWESVIFTALGTDRKVFFNILEEARALALQQEEGKTVMYTAVGSEWRTFGYPRRRRPLDSVVLQQGLADRIVKDIREFIDNPKWYIDRGIPYRRGYLLYGPPGCGKSSFITALAGEVEHSICLLSLTDSSLSDDRLNHLLSVAPQQSLVLLEDVDAAFLSRDLAVENPVKYQGLGRLTFSGLLNALDGVASTEARIVFMTTNHIDRETDAESCTCGHALVLTYLLKLTPGCS", "length": 362, "header": "tr|A0A9J7JE31-1|A0A9J7JE31_CRIGR Computationally mapped isoform of Mitochondrial chaperone BCS1 OS=Cricetulus griseus OX=10029 GN=LOC100771607 PE=3 SV=1 CANONICAL=A0A8C2MWR2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K482-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2/entry#A0A9J7K482-1", "sequence": { "sequence": "MPFTDFVLALKDNPYFGAGFGLVGVGTVLAAARKGAQLGLVAFRRHYMITLEVPARDRSYAWLLSWLTRHSTRTQHLSVETSYLQHESGRISTKFEFIPSPGNHFIWYQGKWIRVQRNRDMQMVDLQTGTPWESVIFTALGTDRKVFFNILEEARALALQQEEGKTVMYTAVGSEWRTFGYPRRRRPLDSVVLQQGLADRIVKDIREFIDNPKWYIDRGIPYRRGYLLYGPPGCGKSSFITALAGEVEHSICLLSLTDSSLSDDRLNHLLSVAPQQSLVLLEDVDAAFLSRDLAVENPVKYQGLGRLTFSGLLNALDGVASTEARIVFMTTNHIDR", "length": 336, "header": "tr|A0A9J7K482-1|A0A8C2MWR2_CRIGR Computationally mapped isoform of Mitochondrial chaperone BCS1 OS=Cricetulus griseus OX=10029 GN=LOC100771607 PE=3 SV=1 CANONICAL=A0A8C2MWR2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K482", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K482" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K482", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K482" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771607", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771607", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AKM3-1", "protein_name": "Mitochondrial chaperone BCS1", "gene_name": "BCS1L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPFSDFVLALKDNPYFGAGFGLVGVGTALALARKGAQLGLVAFRRHYMITLEVPARDRSYAWLLSWLTRHSARTQHLSVETSYLQHESGRISTKFEFVPSPGNHFIWYQGKWIRVERSREMQMIDLQTGTPWESVTFTALGTDRKIFFNILEEARELALQQEEGKTVMYTAVGSEWRPFGYPRRRRPLNSVVLEQGLADRIVRDIREFIDNPKWYTDRGIPYRRGYLLYGPPGCGKSSFITALAGELQHSICLLSLTDSSLSDDRLNHLLSVAPQQSLVLLEDVDAAFLSRDLAAENPVKYQGLGRLTFSGLLNALDGVASTEARIVFMTTNHVDRLDPALIRPGRVDLKEYVGHCSRWQLTQMFQRFYPGQAPSLAESFADRALQATTQISPAQVQGYFMLYKNDPEGAVRHADSLRR", "length": 419 }, "evidence": [ { "id": "A0A8C2MWR2", "url": "https://omabrowser.org/oma/group/A0A8C2MWR2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P32839-1", "protein_name": "Mitochondrial chaperone BCS1", "gene_name": "BCS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSDKPIDIQYDKQATPNLSGVITPPTNETGNDSVREKLSKLVGDAMSNNPYFAAGGGLMILGTGLAVARSGIIKASRVLYRQMIVDLEIQSKDKSYAWFLTWMAKHPQRVSRHLSVRTNYIQHDNGSVSTKFSLVPGPGNHWIRYKGAFILIKRERSAKMIDIANGSPFETVTLTTLYRDKHLFDDILNEAKDIALKTTEGKTVIYTSFGPEWRKFGQPKAKRMLPSVILDSGIKEGILDDVYDFMKNGKWYSDRGIPYRRGYLLYGPPGSGKTSFIQALAGELDYNICILNLSENNLTDDRLNHLMNNMPERSILLLEDIDAAFNKRSQTGEQGFHSSVTFSGLLNALDGVTSSEETITFMTTNHPEKLDAAIMRPGRIDYKVFVGNATPYQVEKMFMKFYPGETDICKKFVNSVKELDITVSTAQLQGLFVMNKDAPHDALKMVSSLRNANHIF", "length": 456 }, "evidence": [ { "id": "A0A8C2MWR2", "url": "https://omabrowser.org/oma/group/A0A8C2MWR2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54DY9-1", "protein_name": "Probable mitochondrial chaperone BCS1-B", "gene_name": "bcsl1b", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENVITNNNKGLPKSILKFIPEPIQPLFENPFFSAGFGLIGVGSILAMGRKGFQQAMIQSRRYFFVSVEVPSKDKSFHWLMEWLATKKNKNTRHVSVETTFHQHESGDIVSRINFVPSVGTHYVFYRGRVIKVERSREKNVIDMNSGNLWESITLTTLGTGRQVFQNLIEEAKEMALEKEEGKTLIYTSMGTDWRRFGHPRRKRPISSVILDKGKSELIIQDVKKFLNNSDWYNDRGIPYRRGYLLYGPPGTGKSSFITALAGELQLSICILNLAGKSVSDTSLNQLLATAPQRSIILLEDIDSAIQTGNHDLSAKSNSANAPSISSGGLQYQGYYGNPSVSSGGSALTFSGLLNALDGVAASEGRILFMTTNHLEKLDKVLIRPGRVDLQIEIGLCSSYQMEQMFLKFYPTDFDLAKQFVEKLENYKFSPAQLQAYFMTYSNNSIEAINNLNELIKK", "length": 458 }, "evidence": [ { "id": "A0A8C2MWR2", "url": "https://omabrowser.org/oma/group/A0A8C2MWR2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5E9H5-1", "protein_name": "Mitochondrial chaperone BCS1", "gene_name": "BCS1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPLSDFVLALKDNPYFGAGFGLVGVGTALALARKGAQLGLVAFRRHYMITLEVPARDRSYAWLLSWLTRHSTRTQHLSVETTYLQHESGRISTKFEFVPSPGNHFIWYQGKWIRVERSREMQMIDLQTGTPWESVTFTALGTDRKVFFNILEEARELALQQEEGKTVMYTAVGSEWRPFGYPRRRRPLNSVVLEQGVTERIVRDIREFIDNPKWYIDRGIPYRRGYLLYGPPGCGKSSFITALAGELQHSICLLSLTDSSLSDDRLNHLLSVAPQQSLVLLEDVDAAFLSRDLAAENPIKYQGLGRLTFSGLLNALDGVASTEARIVFMTTNHIDRLDPALIRPGRVDMKEYVGHCSRWQLTQMFQRFYPGQATSLAENFADRVLQATTQISPAQVQGYFMLYKNDPAGAIQNAESLRR", "length": 419 }, "evidence": [ { "id": "A0A8C2MWR2", "url": "https://omabrowser.org/oma/group/A0A8C2MWR2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7ZV60-1", "protein_name": "Mitochondrial chaperone BCS1", "gene_name": "bcs1l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLSDFIGALKDNPYFGAGFGLVGVGTALAVARKGAQVGMIFFRRHYMITLEVPSKDKSYHWLLSWITKHAKHTQHLSVETSYMQHESGKVHTQFDFHPSPGNHIIWYGRKWIRVERVREKQMMDLHTGTPWESVTFTALGRDRQTFFNILQEARELALKQEEGRTVMYTAMGAEWRPFGFPRRRRPLSSVVLESGVAERIVDDVKEFIGNPKWYTDRGIPYRRGYLLYGPPGCGKSSFITALAGELGYSICLMSLSDRSLSDDRLNHLLSVAPQQSIILLEDVDAAFVSRELLPTENPLAYQGMGRLTFSGLLNALDGVASSEARIVFMTTNFIERLDPALVRPGRVDLKQYVGHCSHWQLTQMFRRFYPQESAAEADHFSEQALAAHTDLSAAQVQGHFMLYKTDPAGAIKNIAEIKD", "length": 420 }, "evidence": [ { "id": "A0A8C2MWR2", "url": "https://omabrowser.org/oma/group/A0A8C2MWR2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9CZP5-1", "protein_name": "Mitochondrial chaperone BCS1", "gene_name": "Bcs1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPFSDFVLALKDNPYFGAGFGLVGVGTALAMARKGAQLGLVAFRRHYMITLEVPARDRSYAWLLSWLTRHSTRTQHLSVETSYLQHESGRISTKFEFIPSPGNHFIWYQGKWIRVERNRDMQMVDLQTGTPWESVTFTALGTDRKVFFNILEEARALALQQEEGKTVMYTAVGSEWRTFGYPRRRRPLDSVVLQQGLADRIVKDIREFIDNPKWYIDRGIPYRRGYLLYGPPGCGKSSFITALAGELEHSICLLSLTDSSLSDDRLNHLLSVAPQQSLVLLEDVDAAFLSRDLAVENPIKYQGLGRLTFSGLLNALDGVASTEARIVFMTTNYIDRLDPALIRPGRVDLKEYVGYCSHWQLTQMFQRFYPGQAPSLAENFAEHVLKATSEISPAQVQGYFMLYKNDPMGAVHNIESLR", "length": 418 }, "evidence": [ { "id": "A0A8C2MWR2", "url": "https://omabrowser.org/oma/group/A0A8C2MWR2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VL22-1", "protein_name": "Mitochondrial chaperone BCS1", "gene_name": "Bcs1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTLPDLVAGLSSNPYFGAGFGLFGVGAAAAILRKGLQGGVILFRRHCMITLEVPCRDKSYQWLLKWITIRGARKTQHLSVETNFVQNDNGTIKTSYDFIPSIGKHLFQYKGNWIQVERTREQQTLDLHMGVPWETVTLTAFGNNKGIYFDILEEARQLALEATEGKTVLYTAMGAEWRPFGHPRRRRPTGSVVLDRGTSQRIIADCQDFIKSSLWYTQRGIPYRRGYLLYGPPGCGKSSFITALAGELEYSVCLLNLSERGLTDDRLNHLLNVAPEQSIILLEDIDAAFVSREATPQQKSAFDGLNRITFSGLLNCLDGVGSTEARIVFMTTNYIDRLDPALVRPGRIDLKEYIGYCTQYQLEEMFKNFFASSDTTKAEEFGKRVNSFGRSASPAQIQGFFMKHKLSSPQTVIDSCEDIWENVLDHNKKIN", "length": 431 }, "evidence": [ { "id": "A0A8C2MWR2", "url": "https://omabrowser.org/oma/group/A0A8C2MWR2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y276-1", "protein_name": "Mitochondrial chaperone BCS1", "gene_name": "BCS1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLSDFILALKDNPYFGAGFGLVGVGTALALARKGVQLGLVAFRRHYMITLEVPARDRSYAWLLSWLTRHSTRTQHLSVETSYLQHESGRISTKFEFVPSPGNHFIWYRGKWIRVERSREMQMIDLQTGTPWESVTFTALGTDRKVFFNILEEARELALQQEEGKTVMYTAVGSEWRPFGYPRRRRPLNSVVLQQGLADRIVRDVQEFIDNPKWYTDRGIPYRRGYLLYGPPGCGKSSFITALAGELEHSICLLSLTDSSLSDDRLNHLLSVAPQQSLVLLEDVDAAFLSRDLAVENPVKYQGLGRLTFSGLLNALDGVASTEARIVFMTTNHVDRLDPALIRPGRVDLKEYVGYCSHWQLTQMFQRFYPGQAPSLAENFAEHVLRATNQISPAQVQGYFMLYKNDPVGAIHNAESLRR", "length": 419 }, "evidence": [ { "id": "A0A8C2MWR2", "url": "https://omabrowser.org/oma/group/A0A8C2MWR2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mitochondrial respiratory chain complex I assembly", "id": "GO:0032981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032981", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex IV assembly", "id": "GO:0033617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033617", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex III assembly", "id": "GO:0034551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034551", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWR2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3H6T7-1", "G3H7V9-1", "G3HCT4-1", "G3HIC5-1", "G3HIL5-1", "A0A061IR73-1", "G3GXG9-1", "G3I8R9-1", "G3HH18-1", "A0A9J7FU33-1", "G3I2I1-1", "A0A9J7FTT2-1", "G3IEZ7-1", "G3HKQ8-1", "G3HMB1-1", "G3HCV0-1", "G3HX41-1", "G3I6K0-1", "G3HTL1-1", "G3HU77-1", "G3HAH5-1", "G3HJ88-1", "G3GSH5-1", "G3GY12-1", "G3I5T3-1", "G3I6L7-1", "G3H484-1", "G3IJD1-1", "G3I008-1", "A0A8C2M596-1", "G3IG24-1", "A0A9J7F876-1", "A0A9J7FI42-1", "A0A9J7G1N4-1", "A0A061IJA4-1", "A0A9J7FPD0-1", "A0A9J7G7V8-1", "A0A9J7JQY5-1", "A0A8C2MCA5-1", "A0A9J7H2D3-1", "A0A9J7G2T1-1", "G3HBU1-1", "G3HUZ6-1", "G3HWS4-1", "A0A9J7HCU3-1", "A0A3L7HMZ7-1", "A0A9J7K3T5-1", "A0A8C2MMI4-1", "A0A9J7GRQ0-1", "A0A8C2N055-1", "A0A8C2QHV1-1", "A0A8C2QM19-1", "A0A8C2M4F5-1", "A0A9J7FJ23-1", "A0A9J7FUH6-1", "A0A9J7G659-1", "A0A9J7K2R5-1", "A0A8C2MB35-1", "G3I478-1", "A0A9J7H1K5-1", "A0A8C2QH91-1", "A0A9J7JQ85-1", "A0A9J7K381-1", "A0A061HU45-1", "A0A061I456-1", "A0A061ICN7-1", "A0A061IKS3-1", "A0A3L7H9D4-1", "A0A9J7H2L4-1", "A0A8C2LZL3-1", "A0A8C2M796-1", "A0A8C2MCS3-1", "A0A8C2MPK3-1", "A0A8C2MQ86-1", "A0A3L7ILF9-1", "A0A3L7INC4-1", "A0A8C2LCW6-1", "A0A8C2LRD7-1", "A0A8C2LSK1-1", "A0A9J7JSD0-1", "P18279-1", "P48975-1", "A0A8C2MVH8-1", "A0A8C2MWE0-1", "A0A8C2MYM8-1", "A0A8C2N236-1", "A0A9J7FYM8-1", "A0A8C2QLX9-1", "A0A8C2QNE7-1", "A0A9J7F9W3-1", "A0A9J7JR19-1", "A0A9J7FPK3-1", "A0A9J7JMF4-1", "A0A9J7FV95-1", "A0A9J7FXI2-1", "A0A9J7G412-1", "A0A9J7G5W9-1", "A0A9J7GCV1-1", "A0A9J7H3Y2-1", "A0A9J7GF88-1", "A0A9J7GHR4-1", "A0A9J7GID0-1", "A0A9J7JVX0-1", "A0A9J7KF39-1", "A0A9J7H4G1-1", "A0A9J7H9J6-1", "A0A9J7JEW1-1", "A0A9J7JIL5-1", "A0A9J7FCH5-1", "A0A8C2MFM1-1", "A0A8C2MWH4-1", "A0A8C2LG83-1", "A0A9J7GDX9-1", "A0A9J7H2C5-1", "A0A9J7GN75-1", "A0A9J7JT79-1", "A0A9J7K1D9-1", "A0A061IIX2-1", "A0A8C2M474-1", "A0A8C2N386-1", "A0A9J7GR00-1", "O35501-1", "P18708-1", "P19378-1", "P46633-1", "Q60452-1", "A0A8C2LBG1-1", "A0A8C2LR22-1", "A0A8C2M4G0-1", "A0A8C2M6G7-1", "G3HCS2-1", "P70099-1", "A0A9J7FI19-1", "A0A9J7G6M1-1", "A0A9J7FJ37-1", "A0A9J7G7R5-1", "A0A8C2MAV3-1", "A0A8C2N184-1", "A0A9J7F1E5-1", "A0A8C2MBY6-1", "A0A9J7JLC6-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HU45", "gene_name": "Ercc6l", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061HU45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HU45" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A061HU45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HU45" } ] } ] }, { "uniprot_ac": "A0A061I456", "gene_name": "Ruvbl2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061I456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I456" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A061I456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I456" } ] } ] }, { "uniprot_ac": "A0A061ICN7", "gene_name": "Mtrex", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061ICN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ICN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A061ICN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ICN7" } ] } ] }, { "uniprot_ac": "A0A061IIX2", "gene_name": "Ddx58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061IIX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IIX2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A061IIX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IIX2" } ] } ] }, { "uniprot_ac": "A0A061IJA4", "gene_name": "Dhx29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061IJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A061IJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA4" } ] } ] }, { "uniprot_ac": "A0A061IKS3", "gene_name": "Helq", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061IKS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IKS3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A061IKS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IKS3" } ] } ] }, { "uniprot_ac": "A0A061IR73", "gene_name": "PEX6", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A061IR73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IR73" } ] } ] }, { "uniprot_ac": "A0A3L7H9D4", "gene_name": "Dhx58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3L7H9D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9D4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3L7H9D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9D4" } ] } ] }, { "uniprot_ac": "A0A3L7HMZ7", "gene_name": "Ddx51", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3L7HMZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMZ7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3L7HMZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMZ7" } ] } ] }, { "uniprot_ac": "A0A3L7ILF9", "gene_name": "Skiv2l", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3L7ILF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ILF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3L7ILF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ILF9" } ] } ] }, { "uniprot_ac": "A0A3L7INC4", "gene_name": "Dhx15", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3L7INC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3L7INC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INC4" } ] } ] }, { "uniprot_ac": "A0A8C2LBG1", "gene_name": "Dna2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "A0A8C2LBG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LBG1" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2LBG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LBG1" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8C2LBG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LBG1" } ] } ] }, { "uniprot_ac": "A0A8C2LCW6", "gene_name": "Ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2LCW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCW6" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8C2LCW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCW6" } ] } ] }, { "uniprot_ac": "A0A8C2LG83", "gene_name": "Ddx43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2LG83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LG83" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2LG83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LG83" } ] } ] }, { "uniprot_ac": "A0A8C2LR22", "gene_name": "Dhx16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2LR22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR22" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2LR22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR22" } ] } ] }, { "uniprot_ac": "A0A8C2LRD7", "gene_name": "Mcm3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2LRD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRD7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8C2LRD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRD7" } ] } ] }, { "uniprot_ac": "A0A8C2LSK1", "gene_name": "Eif4a1", "activity": [ { 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"3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2M596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M596" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2M596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M596" } ] } ] }, { "uniprot_ac": "A0A8C2M6G7", "gene_name": "Ddx1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2M6G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6G7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2M6G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6G7" } ] } ] }, { "uniprot_ac": "A0A8C2M796", "gene_name": "Ddx27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2M796", "database": "UniProtKB", "url": 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{ "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MB35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB35" } ] } ] }, { "uniprot_ac": "A0A8C2MBY6", "gene_name": "Entpd3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8C2MBY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBY6" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8C2MBY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBY6" } ] } ] }, { "uniprot_ac": "A0A8C2MCA5", "gene_name": "Ddx41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MCA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCA5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MCA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCA5" } ] } ] }, { "uniprot_ac": "A0A8C2MCS3", "gene_name": "Ddx47", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MCS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCS3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MCS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCS3" } ] } ] }, { "uniprot_ac": "A0A8C2MFM1", "gene_name": "Vps4b", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFM1" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8C2MFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFM1" } ] } ] }, { "uniprot_ac": 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= ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MQ86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ86" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MQ86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ86" } ] } ] }, { "uniprot_ac": "A0A8C2MVH8", "gene_name": "Mcm7", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MVH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVH8" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8C2MVH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVH8" } ] } ] }, { "uniprot_ac": "A0A8C2MWE0", "gene_name": "Snrnp200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWE0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWE0" } ] } ] }, { "uniprot_ac": "A0A8C2MWH4", "gene_name": "Ddx25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MWH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MWH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ] } ] }, { "uniprot_ac": "A0A8C2MYM8", "gene_name": "Tdrd9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYM8" } ] } ] }, { "uniprot_ac": "A0A8C2N055", "gene_name": "Ythdc2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2N055", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N055" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2N055", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N055" } ] } ] }, { "uniprot_ac": "A0A8C2N184", "gene_name": "Entpd8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8C2N184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N184" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8C2N184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N184" } ] } ] }, { "uniprot_ac": "A0A8C2N236", "gene_name": "Atp13a4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8C2N236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N236" } ] } ] }, { "uniprot_ac": "A0A8C2N386", "gene_name": "Vcp", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2N386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N386" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8C2N386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N386" } ] } ] }, { "uniprot_ac": "A0A8C2QH91", "gene_name": "Ino80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8C2QH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH91" } ] } ] }, { "uniprot_ac": "A0A8C2QHV1", "gene_name": "Ddx20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] } ] }, { "uniprot_ac": "A0A8C2QLX9", "gene_name": "Ddx52", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QLX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLX9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QLX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLX9" } ] } ] }, { "uniprot_ac": "A0A8C2QM19", "gene_name": "Clpx", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QM19" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8C2QM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QM19" } ] } ] }, { "uniprot_ac": "A0A8C2QNE7", "gene_name": "Eif4a3", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNE7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNE7" } ] } ] }, { "uniprot_ac": "A0A9J7F1E5", "gene_name": "Hltf", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A9J7F1E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A9J7F1E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E5" } ] } ] }, { "uniprot_ac": "A0A9J7F876", "gene_name": "Ddx11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7F876", "database": 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"https://www.uniprot.org/uniprotkb/A0A9J7FCH5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCH5" } ] } ] }, { "uniprot_ac": "A0A9J7FI19", "gene_name": "Xrcc6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": 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"", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FJ37", "gene_name": "Mcm9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ37" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ37" } ] } ] }, { "uniprot_ac": "A0A9J7FPD0", "gene_name": "Dhx32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FPD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FPD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPD0" } ] } ] }, { 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phosphate + H(+).", "evidence": [ { "id": "A0A9J7FXI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXI2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FXI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXI2" } ] } ] }, { "uniprot_ac": "A0A9J7FYM8", "gene_name": "Ddx54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYM8" } ] } ] }, { "uniprot_ac": "A0A9J7G1N4", "gene_name": "Fancm", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G1N4", "database": "UniProtKB", "url": 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"activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] }, { "ec_number": "3.1.13.1", "activity": "", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] } ] }, { "uniprot_ac": "A0A9J7G5W9", "gene_name": "Spata5l1", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A9J7G5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W9" } ] } ] }, { "uniprot_ac": "A0A9J7G659", "gene_name": "Rtel1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A0A9J7G659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G659" } ] } ] }, { "uniprot_ac": "A0A9J7G6M1", "gene_name": "Mcm8", "activity": [ { "ec_number": "2.7.8.41", "activity": "a CDP-1,2-diacyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + CMP + H(+).", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M1" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M1" } ] }, { "ec_number": "2.7.8.41", "activity": "", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": 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"evidence": [ { "id": "A0A9J7G7V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G7V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8" } ] } ] }, { "uniprot_ac": "A0A9J7GCV1", "gene_name": "Ddx31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GCV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7GCV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1" } ] } ] }, { "uniprot_ac": "A0A9J7GDX9", "gene_name": "Hfm1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7GDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9" } ] } ] }, { "uniprot_ac": "A0A9J7GF88", "gene_name": "Dhx33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GF88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF88" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7GF88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF88" } ] } ] }, { "uniprot_ac": "A0A9J7GHR4", "gene_name": "Ercc2", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7GHR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHR4" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7GHR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHR4" } ] } ] }, { "uniprot_ac": "A0A9J7GID0", "gene_name": "LOC103158905", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GID0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GID0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7GID0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GID0" } ] } ] }, { "uniprot_ac": "A0A9J7GN75", "gene_name": "LOC100753355", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GN75" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7GN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GN75" } ] } ] }, { "uniprot_ac": "A0A9J7GR00", "gene_name": "Entpd1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A9J7GR00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR00" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A9J7GR00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR00" } ] } ] }, { "uniprot_ac": "A0A9J7GRQ0", "gene_name": "Ak6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A9J7GRQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRQ0" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A9J7GRQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRQ0" } ] } ] }, { "uniprot_ac": "A0A9J7H1K5", "gene_name": "LOC100755041", 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035297271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297271" } ] }, { "annotation": "Might play a role in the development of cardiac outflow tract.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWT1#function" }, { "database": "UniProtKB", "id": "ARBA00053791", "url": "https://www.uniprot.org/uniprotkb/ARBA00053791#function" }, { "database": "UniProtKB", "id": "A0A9J7GUQ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GUQ1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWT1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mctp2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWT1", "locus": {} } ], "crossref": [ { "id": "cd04042", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04042", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08376", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08376", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08377", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08377", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754928", "url": "https://www.ncbi.nlm.nih.gov/gene/100754928", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754928", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754928", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YEADEMK", "url": "https://omabrowser.org/oma/group/YEADEMK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MWT1", "url": "https://www.orthodb.org/?gene=A0A8C2MWT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45911", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45911", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45911:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45911:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035297271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297271", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MWT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MWT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GUQ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GUQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GUQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GUQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLDKPSVWGSLKQRTRPLLINLSKKKAKKNPSKPLDLRVQHHLDRRLSLSVPDLLEAETLAPEGRPYSGPQSSYTSVPNSLSTAGIVPKSSSSSLKQSEEELDWSQEEVSHVHALDTDSEEIYASSAEERPASSQSGLDLQKHPLGGDTPEEPEKSRGNDDLNASMTSHHFEEESTLGEAGDCLSHLPSPFAYLLTIHLKEGRNLVVRDRCGTSDPYVKFKLNGKTLYKSKVIYKNLNPIWDEIVVLPIHSLDQKLRVKVYDRDLTTSDFMGSAFVILRDLELNRTTEHILKLEDPNSLEDDMGVIVLNLNLVVKQGDFKRHRWSNRKRLSASKSSLIRNLRLSESLRKNQLWNGIISITLLEGKNVSGGNMSEMFVQLKLGDQRYKSKTLCKSANPQWQEQFDFHYFSDRMGILDIEVWGKDSKKHEERLGTCKVDISALPLKQDNCLELPLESCLGALIMLITLTPCSGVSISDLCVCPLEDPSERKQISQRYALQNSLKDVKDVGILQVKVLKAADLLAADFSGKSDPFCLLELGNDRLQTHTIYKSLNPEWNKVFTFPIKDIHDVLEVTVFDEDGDKAPDFLGKVAIPLLSIRDGQPNCYVLKNKDLEQAFKGLIYLEMDLIYNPVKASIRTFTPKEKRFVEDSRKLSKKILSRDADRVKRLTMAVWNTIQFFKSCFQWESTLRSSIAFVVFLVTVWNFELYMIPLALLLIFLYNFLRPTKGKASSTQDSQDGTDVDEEEAEEEKESEKKGLIERIYMVQDIVSTVQNILEEVASFGERIKNMFNWTVPFLSLLACLILAIATVALYFIPLRYIVLLWGINKFTKKLRNPYSIDNNELLDFLSRVPSDVQKVQYAELKLCGSHSPLRKKRYTV", "length": 878, "header": "tr|A0A8C2MWT1-1|A0A8C2MWT1_CRIGR Isoform 1 of Multiple C2 and transmembrane domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Mctp2 PE=3 SV=1 CANONICAL=A0A8C2MWT1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MWT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWT1/entry#A0A8C2MWT1-1", "sequence": { "sequence": "MDLDKPSVWGSLKQRTRPLLINLSKKKAKKNPSKPLDLRVQHHLDRRLSLSVPDLLEAETLAPEGRPYSGPQSSYTSVPNSLSTAGIVPKSSSSSLKQSEEELDWSQEEVSHVHALDTDSEEIYASSAEERPASSQSGLDLQKHPLGGDTPEEPEKSRGNDDLNASMTSHHFEEESTLGEAGDCLSHLPSPFAYLLTIHLKEGRNLVVRDRCGTSDPYVKFKLNGKTLYKSKVIYKNLNPIWDEIVVLPIHSLDQKLRVKVYDRDLTTSDFMGSAFVILRDLELNRTTEHILKLEDPNSLEDDMGVIVLNLNLVVKQGDFKRHRWSNRKRLSASKSSLIRNLRLSESLRKNQLWNGIISITLLEGKNVSGGNMSEMFVQLKLGDQRYKSKTLCKSANPQWQEQFDFHYFSDRMGILDIEVWGKDSKKHEERLGTCKVDISALPLKQDNCLELPLESCLGALIMLITLTPCSGVSISDLCVCPLEDPSERKQISQRYALQNSLKDVKDVGILQVKVLKAADLLAADFSGKSDPFCLLELGNDRLQTHTIYKSLNPEWNKVFTFPIKDIHDVLEVTVFDEDGDKAPDFLGKVAIPLLSIRDGQPNCYVLKNKDLEQAFKGLIYLEMDLIYNPVKASIRTFTPKEKRFVEDSRKLSKKILSRDADRVKRLTMAVWNTIQFFKSCFQWESTLRSSIAFVVFLVTVWNFELYMIPLALLLIFLYNFLRPTKGKASSTQDSQDGTDVDEEEAEEEKESEKKGLIERIYMVQDIVSTVQNILEEVASFGERIKNMFNWTVPFLSLLACLILAIATVALYFIPLRYIVLLWGINKFTKKLRNPYSIDNNELLDFLSRVPSDVQKVQYAELKLCGSHSPLRKKRYTV", "length": 878, "header": "tr|A0A8C2MWT1-1|A0A8C2MWT1_CRIGR Isoform 1 of Multiple C2 and transmembrane domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Mctp2 PE=3 SV=1 CANONICAL=A0A8C2MWT1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GUQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWT1/entry#A0A9J7GUQ1-1", "sequence": { "sequence": "MDLDKPSVWGSLKQRTRPLLINLSKKKAKKNPSKPLDLRVQHHLDRRLSLSVPDLLEAETLAPEGRPYSGPQSSYTSVPNSLSTAGIVPKSSSSSLKQSEEELDWSQEEVSHVHALDTDSEEIYASSAEERPASSQSGLDLQKHPLGGDTPEEPEKSRGNDDLNASMTSHHFEEESTLGEAGDCLSHLPSPFAYLLTIHLKEGRNLVVRDRCGTSDPYVKFKLNGKTLYKSKVIYKNLNPIWDEIVVLPIHSLDQKLRVKVYDRDLTTSDFMGSAFVILRDLELNRTTEHILKLEDPNSLEDDMGVIVLNLNLVVKQGDFKRHRWSNRKRLSASKSSLIRNLRLSESLRKNQLWNGIISITLLEGKNVSGGNMSEMFVQLKLGDQRYKSKTLCKSANPQWQEQFDFHYFSDRMGILDIEVWGKDSKKHEERLGTCKVDISALPLKQDNCLELPLESCLGALIMLITLTPCSGVSISDLCVCPLEDPSERKQISQRYALQNSLKDVKDVGILQVKVLKAADLLAADFSGKSDPFCLLELGNDRLQTHTIYKSLNPEWNKVFTFPIKDIHDVLEVTVFDEDGDKAPDFLGKVAIPLLSIRDGQPNCYVLKNKDLEQAFKGLIYLEMDLIYNPVKASIRTFTPKEKRFVEDSRKLSKKILSRDADRVKRLTMAVWNTIQFFKSCFQWESTLRSSIAFVESEKKGLIERIYMVQDIVSTVQNILEEVASFGERIKNMFNWTVPFLSLLACLILAIATVALYFIPLRYIVLLWGINKFTKKLRNPYSIDNNELLDFLSRVPSDVQKVQYAELKLCGSHSPLRKKRYTV", "length": 823, "header": "tr|A0A9J7GUQ1-1|A0A9J7GUQ1_CRIGR Computationally mapped isoform of Multiple C2 and transmembrane domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Mctp2 PE=3 SV=1 CANONICAL=A0A8C2MWT1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWT1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWT1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754928", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754928", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MKH3-1", "protein_name": "Multiple C2 and transmembrane domain-containing protein 2", "gene_name": "Mctp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLDKPSVWGSLKQRTRPLLINLSKKKAKKSPSKPLDLRVQHHLDRRLSLSVPDLLEAEALVPEGRPYSGPQSSYISVPNSLSTAGIVPKSSSSSLKQSEEELEWSQEEASHVPGVDTDSEEIYASPAEEWQAFSQSGLDLHKAPEEPEKTHGSDDLNASMSSQQFEEQLTLGEASDCVSHLPSPFAYLLTIHLKEGRNLVVRDRCGTSDPYVKFKLNGKTLYKSKVIYKNLNPIWDEIVVLPIQSLDQKLRVKVYDRDLTKSDFMGSAFVVLRDLELNRTTEHILKLEDPNSLEDDMGVIVLNLNLVVKQGDFKRQRWSNRKRLSASKSSLIRNLRLSESLRKNQLWNGIISITLLEGKNVSGGNMTEMFVQLKLGEQRYKSKTLCKSENPQWQEQFDFHYFSDRMGILDIEVWGKDNKKHEERLGTCKVDISALPLKQDNCLELPLESCQGALLMLITLTPCTAVSISDLCVCPLEDPSERQLISQRYALQNSLKDVKDVGILQVKVLKAADLLAADFSGKSDPFCLLELGNDRLQTHTIYKNLNPEWNKVFTFPIKDIHDVLEVTVFDEDGDKAPDFLGKVAIPLLSIRDGQPNCYVLKNKDLEQAFKGLIYLELDLIYNPVKASIRTFSPREKRFVEDSRKLSKKILSRDVDRVKRLTMAIWNTIQFFKSCFQWESTLRSTVAFVVFLVTVWNFELYMIPLAMLLLFLYNFLRPMKGKASSTQDSQDSTDIEEEEKEEEKESEKKGIIERIYMVQDIVSTVQNILEEVASFGERIKNTFNWTVPFLSLLACLILAIATVVLYFIPLRYIILLWGINKFTKKLRNPYSIDNNELLDFLSRVPSDIQKVQYAELKLCGSHSPLRKKRSTV", "length": 872 }, "evidence": [ { "id": "A0A8C2MWT1", "url": "https://omabrowser.org/oma/group/A0A8C2MWT1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A287AIU9-1", "protein_name": "Multiple C2 and transmembrane domain-containing protein 2", "gene_name": "MCTP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDLDKPSVWGSLKQRTRPLLINLSKRKVKKNSNKPLDLRARHCLDRRLSLSVPDLLEAEALAPEGRPYSGPQSSYTSVPSSLSTAGIFPKSSSSSLKQSEEELDWSQEEAGHHHVVETDSEETYVSPAEDRRASSNGIFDLFQKTPLGEDGPEESEKLCGSTDLNASLTSQHFEEQSVSDNPSKQTNTTVNTTLREAGDGLSHLPSPFAYLLTIHLKEGRNLVIRDRCGTSDPYVKFKLNGKTLYKSKVIYKNLNPVWDEIVVLPIQSLDQKLRVKVYDRDLTTSDFMGSAFVILSDLELNRTTEHILKLEDPNSLEDDMGVIILNLNLVVKQGDFKRHRWSNRKRLSASKSSLIRNLRLSESLKKNQLWNGIISITLLEGKNVSGGSMTEMFVQLKLGDQRYKSKTLCKSANPQWREQFDFHYFSDRMGILDIEVWGKDSKKHEERLGTCKVDISALPLKQANCLELPLESCPGTLLMLITLTPCAGVSVSDLCVCPLADPSERKQIAQRFCLQNSLKDMKDVGLLQVKVLKAVDLLAADFSGKSDPFCLLELGNDRLQTHTIYKNLNPEWNKVFTFPIKDIHDVLEVTVFDEDGDKPPDFLGKVAIPLLSIRDGQTNCYVLKNKDLEQAFKGVIYLEMDLIYNPIKASIRTFTPREKRFTEDSRKLSKKILSRDVDRVKRITMAIWNTIQFLKSCFQWESTVRSTVAFMVFLVTVWNFELYMIPLALLLLFVYNFIRPTKGKVGSIQESQESTDVDEEEDDDDKPPHMIPDENPAASQRHMLESEKKGLIERIYMVQDIVSTVQNILEEVASFGERIKNTFNWTVPFLSFLACLILAVATITLYFIPLRYIILIWGINKFTKKLRNPYAIDNNELLDFLSRVPSDVQKVQYAELKPCSSQSPLRKKRSAL", "length": 912 }, "evidence": [ { "id": "A0A8C2MWT1", "url": "https://omabrowser.org/oma/group/A0A8C2MWT1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0Z116-1", "protein_name": "Multiple C2 and transmembrane domain-containing protein 2", "gene_name": "MCTP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAVPGWQESLMLLRTRGIAEVPCAAMDLEKPSVWGSLKQRTRPFLQNLSVRKAKKRSSKMVVSKVRSLDRRLSVSVPDMLEVETLTEEETTYSSTQVLSSGYPSGAPRPVVSLKRRNSSMRPEGEDWPWLQPSAACTEPAVARLDVRMADSPVSEGKRPSSDDLLELLQRAHLSTELTSEMMEECGGMDLESSVSSQMFDDQMGAEEGSDCLSHLPSPFAYLLTIHLKEGRNLVIRDRCGTSDPYVKFKLNGKTLYKSKVVYKNLNPVWDETVVLPVQTLDQKLWVKVYDRDLTSSDFMGSAFVALTELELNRTTEQVLKLEDPNSLEDDMGVIVLNLSLAVKQGDFKRNRWSSRKKRSSSKASFMRSMRLSDSLRKNQLWNGQVTITLLEGRNIPFGGLAEVFILLKLGDQRYKSKTLCKSANPQWREQFDFHYFSDRKDMLDIEVWRKDNKKHEELLGTCKVDISALSMKQTNCLELPLEKHPGSLIMLIAVTPCTGVSISDLCVCPLGDPSERKQIAQRYSIKNSFRDMKDVGFLQVKVLKAVDLLAADFAGKSDPFCVLELGNDSLQTHTVYKNLNPEWNKVFTFPIKDIHDVLEVTVFDEDGDKPPDFLGKVAIPLLSIRNGKQSCYMLKNKDLERASKGVIYLELDVLFNPIKATIRTFKPREKRFTEENRKFSKKILSRNVDRVKKITMAIWNTIQFLRSCFLWESTVKSVIAFVVFVVTVWSVELYMVPLALLVLFAYNFSLVRTGKVNNTQDAQELMGLDEDDDEEDKESEKKGIIDRIHMVQEIIVAVQSILEEIASFGERIKNTLNWTVPFLSVLACLFLAAATVILYFIPLRYIILIWGINKFTKKLRNPYAIDNNELLDFLSRVPSDVQKVQHAELKPYSSSSPIRKKRSAL", "length": 905 }, "evidence": [ { "id": "A0A8C2MWT1", "url": "https://omabrowser.org/oma/group/A0A8C2MWT1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5RJH2-1", "protein_name": "Multiple C2 and transmembrane domain-containing protein 2", "gene_name": "Mctp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLDKPSVWGSLKQRTRPLLINLSKKKAKKSPSKPLDLRVQHHLDRRLSLSVPDLLEAEALAPEGRPYSGPQSSYISVPNSLSTAGIVPKSSSSSLKQSEEELDWSQEEASHVHGVDTDSEEIYASPAEEWQAFSQSALDLHKPSLGRDAPEEHDKTHGNDDLNASMTSQHFEEESTLGEASDCVSHLPSPFAYLLTIHLKEGRNLVVRDRCGTSDPYVKFKLNGKTLYKSKVIYKNLNPIWDEIVVLPIQSLDQKLRVKVYDRDLTKSDFMGSAFVVLRDLELNRTTEHILKLEDPNSLEDDMGVIVLNLNLVVKQGDFKRHRWSNRKRLSASKSSLIRNLRLSESLRKNQLWNGIISITLLEGKNVSGGNMTEMFVQLKLGEQRYKSKTLCKSANPQWQEQFDFHYFSDRMGILDIEVWGKDSKKHEERLGTCKVDISALPLKQDNCLELPLESCQGALLMLITLTPCTGVSISDLCVCPFEDPSERQQISQRYAFQNSLKDVKDVGILQVKVLKASDLLAADFSGKSDPFCLLELGNDRLQTHTIYKNLNPEWNKVFTFPIKDIHDVLEVTVFDEDGDKAPDFLGKVAIPLLSIRDGQPNCYVLKNKDLEQAFKGLIYLELDLIYNPVKASIRTFTPREKRFVEDSRKLSKKILSRDVDRVKRLTLAIWNTVQFFKSCFQWESTLRSTIAFVVFLVTVWNFELYMIPLALLLLFLYNFLRPMKGKASSTQDSQESTDVEEEGKEEEKESEKKGIIERIYMVQDIVSTVQNILEEVASFGERIKNVFNWTVPFLSLLACLILAITTVILYFIPLRYIILLWGINKFTKKLRNPYSIDNNELLDFLSRVPSDIQKVQYAELKLCGSHSPLRKKRSTV", "length": 878 }, "evidence": [ { "id": "A0A8C2MWT1", "url": "https://omabrowser.org/oma/group/A0A8C2MWT1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6DN12-1", "protein_name": "Multiple C2 and transmembrane domain-containing protein 2", "gene_name": "MCTP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLDKPSVWGSLKQRTRPLLINLSKKKVKKNPSKPPDLRARHHLDRRLSLSVPDLLEAEALAPEGRPYSGPQSSYTSVPSSLSTAGIFPKSSSSSLKQSEEELDWSQEEASHLHVVETDSEEAYASPAERRRVSSNGIFDLQKTSLGGDAPEEPEKLCGSSDLNASMTSQHFEEQSVPGEASDGLSNLPSPFAYLLTIHLKEGRNLVVRDRCGTSDPYVKFKLNGKTLYKSKVIYKNLNPVWDEIVVLPIQSLDQKLRVKVYDRDLTTSDFMGSAFVILSDLELNRTTEHILKLEDPNSLEDDMGVIVLNLNLVVKQGDFKRHRWSNRKRLSASKSSLIRNLRLSESLKKNQLWNGIISITLLEGKNVSGGSMTEMFVQLKLGDQRYKSKTLCKSANPQWQEQFDFHYFSDRMGILDIEVWGKDNKKHEERLGTCKVDISALPLKQANCLELPLDSCLGALLMLVTLTPCAGVSVSDLCVCPLADLSERKQITQRYCLQNSLKDVKDVGILQVKVLKAADLLAADFSGKSDPFCLLELGNDRLQTHTVYKNLNPEWNKVFTFPIKDIHDVLEVTVFDEDGDKPPDFLGKVAIPLLSIRDGQPNCYVLKNKDLEQAFKGVIYLEMDLIYNPVKASIRTFTPREKRFVEDSRKLSKKILSRDVDRVKRITMAIWNTMQFLKSCFQWESTLRSTIAFAVFLITVWNFELYMIPLALLLIFVYNFIRPVKGKVSSIQDSQESTDIDDEEDEDDKESEKKGLIERIYMVQDIVSTVQNVLEEIASFGERIKNTFNWTVPFLSSLACLILAAATIILYFIPLRYIILIWGINKFTKKLRNPYSIDNNELLDFLSRVPSDVQKVQYAELKLCSSHSPLRKKRSAL", "length": 878 }, "evidence": [ { "id": "A0A8C2MWT1", "url": "https://omabrowser.org/oma/group/A0A8C2MWT1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q84TJ7-1", "protein_name": "Multiple C2 domain and transmembrane region protein 7", "gene_name": "MCTP7", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMMSNLKLGVDVIGAHNLFPKDGQGTSNAYVELYFDGQKHRTTIKDRDLNPVWNESFFFNISDPSRLHYLNLEAQAYSHNRSTNGRSFLGKVSLSGTSFVPHSDAVVLHFPMERRGIFSRVRGELGLKVYITDEASLKSSAASNDHPDNLDPALPRAMNVEHRSDKRHVFYNLPNSAQEHQHQHPQGPNQSSSLAAEQDNHNEHHHHYVPKHQVDEMRSEPARPSKLVHAHSIASAQPADFALKETSPHLGGGRVVGGRVIHKDKTATSTYDLVERMYFLYVRVVKARELPIMDITGSVDPFVEVRVGNYKGITRHFEKRQHPEWNQVFAFAKERMQASVLEVVVKDKDLLKDDYVGFVRFDINDVPLRVPPDSPLAPQWYRLEDKKGEKIKGELMLAVWIGTQADEAFSDAWHSDAAMPVDCSPAISAVLRSKVYHAPRLWYVRVNVIEAQDLIPTDKTRFPDVYVKAQLGNQVMKTRPCQARTLGAVWNEDFLFVVAEPFEDHLVLTVEDRVAPGKDEIVGRTYIPLNTVEKRADDHMIHARWYNLERPVIVDVDQLKREKFSMRIHLRVCLEGGYHVLDESTHYSSDLRPSARPLWRQPIGVLELGILNAVGLHPMKTREGRGTSDTFCVGKYGQKWVRTRTMVDNLCPKYNEQYTWEVFDPATVLTVGVFDNGQLGEKGNRDVKIGKIRIRLSTLETGRIYTHSYPLLVLHPTGVKKMGELHMAVRFTCISFANMLYQYSKPLLPKMHYVRPFSVMQQDMLRHQAVNIVAARLGRAEPPLRKEIIEFMSDTDSHLWSMRKSKANFFRMMTVFSGVIAVGKWFSDICSWRNPITTVLVHVLFLMLVCLPELILPTMFLYMFLIGLWNYRFRPRYPPHMNTKISQAEAVHPDELDEEFDTFPTTRNPDMVRLRYDRLRSVAGRIQTVIGDLATQGERFQALLSWRDPRATAIFVILCFIAAIVFFITPIQIVVALAGFFTMRHPRFRHRLPSVPVNFFRRLPARTDSML", "length": 1011 }, "evidence": [ { "id": "A0A8C2MWT1", "url": "https://omabrowser.org/oma/group/A0A8C2MWT1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWT1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWT1" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWT1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWT1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of neurotransmitter secretion", "id": "GO:0046928", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046928", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": 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"sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 22, "end_pos": 24 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 367, "end_pos": 369 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 790, "end_pos": 792 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MWX0-1", "uniprot_ac": "A0A8C2MWX0", "uniprot_id": "A0A8C2MWX0_CRIGR", "mass": { "chemical_mass": 59126.0, "monoisotopic_mass": 59126.0 }, "refseq": { "ac": "XP_007640618", "name": "ran-binding protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640618" }, "gene_names": [ { "name": "Ranbp3", "type": "recommended", "evidence": [ { "id": "A0A8C2MWX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWX0" } ] }, { "name": "Ranbp3", "type": "synonym", "evidence": [ { "id": "XP_007640618", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640618" } ] } ], "protein_names": [ { "name": "Ran-binding protein 3", "type": "recommended", "evidence": [ { "id": "A0A8C2MWX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWX0/entry#names_and_taxonomy" } ] }, { "name": "ran-binding protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007640618", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640618" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 16 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613861.1) and transcript sequence (IACG01087926.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007640618", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640618" } ] }, { "annotation": "Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWX0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWX0#function" }, { "database": "UniProtKB", "id": "ARBA00058720", "url": "https://www.uniprot.org/uniprotkb/ARBA00058720#function" }, { "database": "UniProtKB", "id": "A0A8C2N0D7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0D7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWX0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWX0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ranbp3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWX0", "locus": {} } ], "crossref": [ { "id": "cd13180", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13180", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771967", "url": "https://www.ncbi.nlm.nih.gov/gene/100771967", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771967", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771967", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MWX0", "url": "https://www.orthodb.org/?gene=A0A8C2MWX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23138", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23138", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23138:SF91", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23138:SF91", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00638", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00638", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007640618", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640618", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MWX0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MWX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0D7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0D7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0D7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0D7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADLANEEKPAVAPSVFVFQKDKGQKSSTEHKDLPESGEEPRGEAEAPRPDAGHPESAGEHALDPPAPASASASSPPPPAPAAQPPCVRELSGRSAGSSSPEAGEDSDHEDGNYCPPVKRERTSSLTHAEEKSSGFRLKPPTLIHGQAPSAGLPSQKPREQQRGVLRPAVLQAPQPKVLSQTVPSSGTNGVSVPADCTGPATSASPENLTQKSPSEPPDGTNILEEKVLQKTPHGTSEEGHCEEEQVAPQAFVFGQNLRDRVKLMNENADVAGVDSAAYPSSETPTATNYFLQYISSGADNSTHSADTSNKFVFGQNMSERVLSPPKLNEASSDASRETTHTQSGSEPSSQEAAPKKESLAESAAAYTKATAWTCLLEKVEVITGEEAESNVLQIQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQMDKASEKSIRITATDAEDQGVKVFLISASSKDTGQLYAALHHRILALRSRAEQEQEAKAPAPEPGAPRATEEEDSDEDAVLTPSGVTGAGTGDEGDGQTPGST", "length": 558, "header": "tr|A0A8C2MWX0-1|A0A8C2MWX0_CRIGR Isoform 1 of Ran-binding protein 3 OS=Cricetulus griseus OX=10029 GN=Ranbp3 PE=4 SV=1 CANONICAL=A0A8C2MWX0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MWX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWX0/entry#A0A8C2MWX0-1", "sequence": { "sequence": "MADLANEEKPAVAPSVFVFQKDKGQKSSTEHKDLPESGEEPRGEAEAPRPDAGHPESAGEHALDPPAPASASASSPPPPAPAAQPPCVRELSGRSAGSSSPEAGEDSDHEDGNYCPPVKRERTSSLTHAEEKSSGFRLKPPTLIHGQAPSAGLPSQKPREQQRGVLRPAVLQAPQPKVLSQTVPSSGTNGVSVPADCTGPATSASPENLTQKSPSEPPDGTNILEEKVLQKTPHGTSEEGHCEEEQVAPQAFVFGQNLRDRVKLMNENADVAGVDSAAYPSSETPTATNYFLQYISSGADNSTHSADTSNKFVFGQNMSERVLSPPKLNEASSDASRETTHTQSGSEPSSQEAAPKKESLAESAAAYTKATAWTCLLEKVEVITGEEAESNVLQIQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQMDKASEKSIRITATDAEDQGVKVFLISASSKDTGQLYAALHHRILALRSRAEQEQEAKAPAPEPGAPRATEEEDSDEDAVLTPSGVTGAGTGDEGDGQTPGST", "length": 558, "header": "tr|A0A8C2MWX0-1|A0A8C2MWX0_CRIGR Isoform 1 of Ran-binding protein 3 OS=Cricetulus griseus OX=10029 GN=Ranbp3 PE=4 SV=1 CANONICAL=A0A8C2MWX0-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N0D7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWX0/entry#A0A8C2N0D7-1", "sequence": { "sequence": "MADLANEEKPAVAPSVFVFQKDKGQKRSAGSSSPEAGEDSDHEDGNYCPPVKRERTSSLTHAEEKSSGFRLKPPTLIHGQAPSAGLPSQKPREQQRGVLRPAVLQAPQPKVLSQTVPSSGTNGVSVPADCTGPATSASPENLTQKSPSEPPDGTNILEEKVLQKTPHGTSEEGHCEEEQVAPQAFVFGQNLRDRVKLMNENADVAGVDSAAYPSSETPTATNYFLQYISSGADNSTHSADTSNKFVFGQNMSERVLSPPKLNEASSDASRETTHTQSGSEPSSQEAAPKKESLAESAAAYTKATAWTCLLEKVEVITGEEAESNVLQIQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQMDKASEKSIRITATDAEDQGVKVFLISASSKDTGQLYAALHHRILALRSRAEQEQEAKAPAPEPGAPRATEEEDSDEDAVLTPSGVTGAGTGDEGDGQTPGST", "length": 491, "header": "tr|A0A8C2N0D7-1|A0A8C2N0D7_CRIGR Computationally mapped isoform of Ran-binding protein 3 OS=Cricetulus griseus OX=10029 GN=Ranbp3 PE=4 SV=1 CANONICAL=A0A8C2MWX0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MWX0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWX0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007624992", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007624992" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX30", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gmeb1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30", "locus": {} } ], "crossref": [ { "id": "100769076", "url": "https://www.ncbi.nlm.nih.gov/gene/100769076", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769076", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769076", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SPINQQA", "url": "https://omabrowser.org/oma/group/SPINQQA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MX30", "url": "https://www.orthodb.org/?gene=A0A8C2MX30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10417", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10417", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10417:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10417:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01342", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01342", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25892", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25892", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007624992", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007624992", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MX30", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MX30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGIYDPGSENNAAVVAVETHTIHKIEEGIDTSSIEANEDMEIAYPITCGESKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGNITQIAISEESMEEAGLEWNSALTAAVTMATEEGIKKDSEEISEDTLMFWKGIADVGLMDEVICNIQKEIEELLRGVQQRLIQAPFQVTDAAVLNNVAQTFGLMDTVKRVLDNRRKQVEQGEGQYLYTLADLERQLEEQKKQAQDPRLKPQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPVQQPQFTVISPITITPVGQSFSMGNVPVATLSQGSSPVTVHTLPSGPQLFRYATVVSSAKSSSPDTVTIHPSSSLALLSSTTMQDGSTLGNMATMVSPVELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDPEAEDTEGKAVILETELRTEEKVVAEMEEHQHQVHNVEIVVLED", "length": 562, "header": "tr|A0A8C2MX30-1|A0A8C2MX30_CRIGR Isoform 1 of Glucocorticoid modulatory element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Gmeb1 PE=4 SV=1 CANONICAL=A0A8C2MX30-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MX30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30/entry#A0A8C2MX30-1", "sequence": { "sequence": "MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGIYDPGSENNAAVVAVETHTIHKIEEGIDTSSIEANEDMEIAYPITCGESKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGNITQIAISEESMEEAGLEWNSALTAAVTMATEEGIKKDSEEISEDTLMFWKGIADVGLMDEVICNIQKEIEELLRGVQQRLIQAPFQVTDAAVLNNVAQTFGLMDTVKRVLDNRRKQVEQGEGQYLYTLADLERQLEEQKKQAQDPRLKPQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPVQQPQFTVISPITITPVGQSFSMGNVPVATLSQGSSPVTVHTLPSGPQLFRYATVVSSAKSSSPDTVTIHPSSSLALLSSTTMQDGSTLGNMATMVSPVELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDPEAEDTEGKAVILETELRTEEKVVAEMEEHQHQVHNVEIVVLED", "length": 562, "header": "tr|A0A8C2MX30-1|A0A8C2MX30_CRIGR Isoform 1 of Glucocorticoid modulatory element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Gmeb1 PE=4 SV=1 CANONICAL=A0A8C2MX30-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX30", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX30", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769076", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769076", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SRJ8-1", "protein_name": "Glucocorticoid modulatory element binding protein 1", "gene_name": "GMEB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGIYEAGSENNTAVVAVETHTIHKIEEGIDASTIEANEDMEIAYPITCGESKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGSITQIAISEESMEEAGLEWNSALTAAVTMATEEGVKKDSEEISEDTLMFWKGIADVGLMEEVVCNIQKEIEELLRGVQQRLIQAPFQVTDAAVLNNVAHTFGLMDTVKKVLDNRKNQVEQGEEQFLYTLTDLERQLEEQKKQAQDHRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPPVHQPQFTVISPITITPVGQSFSMGNIPVATLSQGSSPVTVHTLPSGPQLFRYATVVSSAKSSSPDTVTIHPSSSLALLSSTAMQDGSTLGNMTTMVSPVELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDPEAEDTEGKAVILETELRTEEKVVAEMEEHQHQVHNVEIVVLED", "length": 563 }, "evidence": [ { "id": "A0A8C2MX30", "url": "https://omabrowser.org/oma/group/A0A8C2MX30/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9JL60-1", "protein_name": "Glucocorticoid modulatory element-binding protein 1", "gene_name": "Gmeb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGIYEAGSENSAAVVAVETHSIHKIEEGIDASSIEGNEDMEIAYPITCGESKAVLLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGNITQIAISEESMEEAGLEWNSALTAAVTMATEEGIKKESEEISEDTLMFWKGIADVGLMEEVVCNIQKEMEELLRGVQQRLIQAPFQVTDAAVLNNVANTFGLMDAVKRVLDNRRKQVEQGEEQFLYTLADLERQLEEQKKQAQDPRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPVQQPQFTVISPITITPVGQSFSMGNIPVATLSQGSSPVTVHTLPSGPQLFRYATVVSSAKSNSPDTVTIHPSSSLALLSSTSMQDGSSLGNMATMVSPMELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDSEADDTEGKAVILETGLRTEEKVVAEMEEHQHQVHNVEIVVLED", "length": 562 }, "evidence": [ { "id": "A0A8C2MX30", "url": "https://omabrowser.org/oma/group/A0A8C2MX30/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QUZ8-1", "protein_name": "Glucocorticoid modulatory element-binding protein 1", "gene_name": "Gmeb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGIYEAGSENSAAVVAVETHTIHKIEEGIDASSIEANEDMEIAYPITCGESKAVLLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGNITQIAISEESMEEAGLEWNSALTAAVTMATEEGIKKESEEISEDTLMFWKGIADVGLMEEVVCNIQKEIEELLRGVQQRLIHAPFQVTDAAVLNNVANTFGLMDTVKRVLDNRRKQVEHGEEQFLYTLADLERQLEEQKKQAQDPRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPVQQPQFTVISPITITPVGQSFSMGNIPVATLSQGTSPVTVHTLPSGPQLFRYATVVSSAKSNSPDTVTIHPSSSLALLSSTSMQDGSTLGNMATMVSPVELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDPEADDPEGKAVILETELRTEEKVVANMEERQHQVHNVEIVVLED", "length": 562 }, "evidence": [ { "id": "A0A8C2MX30", "url": "https://omabrowser.org/oma/group/A0A8C2MX30/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y692-1", "protein_name": "Glucocorticoid modulatory element-binding protein 1", "gene_name": "GMEB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGLFIDGHFYNRIYEAGSENNTAVVAVETHTIHKIEEGIDTGTIEANEDMEIAYPITCGESKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGSITQIAISEESMEEAGLEWNSALTAAVTMATEEGVKKDSEEISEDTLMFWKGIADVGLMEEVVCNIQKEIEELLRGVQQRLIQAPFQVTDAAVLNNVAHTFGLMDTVKKVLDNRRNQVEQGEEQFLYTLTDLERQLEEQKKQGQDHRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPPVQQPQFTVISPITITPVGQSFSMGNIPVATLSQGSSPVTVHTLPSGPQLFRYATVVSSAKSSSPDTVTIHPSSSLALLSSTAMQDGSTLGNMTTMVSPVELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDPEAEDTEGKAVILETELRTEEKVVAEMEEHQHQVHNVEIVVLED", "length": 573 }, "evidence": [ { "id": "A0A8C2MX30", "url": "https://omabrowser.org/oma/group/A0A8C2MX30/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX30", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX30", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX30", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX30", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX30", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX30", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX30", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX30", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX30", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30" } ], "pmid": "" }, { "name": "Hsp27 protein binding", "id": "GO:0051008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051008", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX30", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MX30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX30" }, { "id": "PS50864", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50864" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAND", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 156, "start_aa": "Thr", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MX41-1", "uniprot_ac": "A0A8C2MX41", "uniprot_id": "A0A8C2MX41_CRIGR", "mass": { "chemical_mass": 54812.0, "monoisotopic_mass": 54812.0 }, "refseq": { "ac": "XP_003495476", "name": "UBX domain-containing protein 7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495476" }, "gene_names": [ { "name": "Ubxn7", "type": "recommended", "evidence": [ { "id": "A0A8C2MX41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41" } ] }, { "name": "Ubxn7", "type": "synonym", "evidence": [ { "id": "XP_003495476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495476" } ] } ], "protein_names": [ { "name": "UBX domain-containing protein 7", "type": "recommended", "evidence": [ { "id": "A0A8C2MX41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41/entry#names_and_taxonomy" } ] }, { "name": "UBX domain-containing protein 7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003495476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495476" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 103 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613591.1) and transcript sequence (JI878618.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003495476.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003495476", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495476" } ] }, { "annotation": "Ubiquitin-binding adapter that links a subset of NEDD8-associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitination substrates.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JPH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPH7#function" }, { "database": "UniProtKB", "id": "ARBA00054798", "url": "https://www.uniprot.org/uniprotkb/ARBA00054798#function" }, { "database": "UniProtKB", "id": "A0A8C2MX41", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX41", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ubxn7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41", "locus": {} } ], "crossref": [ { "id": "cd01773", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01773", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02958", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02958", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14345", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14345", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761607", "url": "https://www.ncbi.nlm.nih.gov/gene/100761607", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761607", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761607", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MX41", "url": "https://www.orthodb.org/?gene=A0A8C2MX41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23322", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23322", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23322:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23322:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13899", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13899", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003495476", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495476", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MX41", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MX41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAHGGSAASSALKGLIQQFTAITGASESVGKHMLEACNNNLEMAVTMFLDGGGIAEEPSTSSASVSAVRPHTEEEVRAPIPQKQEILVEPEPLFGAPKRRRPARSIFDGFRDFQTETIRQEQELRNGGAIDKKLTTLADLFRPPIDLMHKGSFETAKECGQMQNKWLMINIQNVQDFACQCLNRDVWSNEAVKNIIREHFIFWQVYHDSEEGQRYIQFYKLGDFPYVSILDPRTGQKLVEWHQLDVSSFLDQVTGFLGEHGQLDGLSSSPPKKCARSESLIDASEDSQLEAAIRASLQETHFDSAQAKQDSRSDEESESELFSGSEEFISVCGSDEEEEVENLAKSRKSPHKDLGHRKEENRRPMTEPPARTEPGTATNHQGMPAMDPEVLEMSPEKSDGIVEGIDVNGPKAQLMLRYPDGKREQITLPEQAKLLALVKHVQSKGYPNERFELLTNFPRRKLSHLDYDITLQEAGLCPQETVFVQERN", "length": 489, "header": "tr|A0A8C2MX41-1|A0A8C2MX41_CRIGR Isoform 1 of UBX domain-containing protein 7 OS=Cricetulus griseus OX=10029 GN=Ubxn7 PE=4 SV=1 CANONICAL=A0A8C2MX41-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MX41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41/entry#A0A8C2MX41-1", "sequence": { "sequence": "MAAHGGSAASSALKGLIQQFTAITGASESVGKHMLEACNNNLEMAVTMFLDGGGIAEEPSTSSASVSAVRPHTEEEVRAPIPQKQEILVEPEPLFGAPKRRRPARSIFDGFRDFQTETIRQEQELRNGGAIDKKLTTLADLFRPPIDLMHKGSFETAKECGQMQNKWLMINIQNVQDFACQCLNRDVWSNEAVKNIIREHFIFWQVYHDSEEGQRYIQFYKLGDFPYVSILDPRTGQKLVEWHQLDVSSFLDQVTGFLGEHGQLDGLSSSPPKKCARSESLIDASEDSQLEAAIRASLQETHFDSAQAKQDSRSDEESESELFSGSEEFISVCGSDEEEEVENLAKSRKSPHKDLGHRKEENRRPMTEPPARTEPGTATNHQGMPAMDPEVLEMSPEKSDGIVEGIDVNGPKAQLMLRYPDGKREQITLPEQAKLLALVKHVQSKGYPNERFELLTNFPRRKLSHLDYDITLQEAGLCPQETVFVQERN", "length": 489, "header": "tr|A0A8C2MX41-1|A0A8C2MX41_CRIGR Isoform 1 of UBX domain-containing protein 7 OS=Cricetulus griseus OX=10029 GN=Ubxn7 PE=4 SV=1 CANONICAL=A0A8C2MX41-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JPH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41/entry#A0A9J7JPH7-1", "sequence": { "sequence": "MAAHGGSAASSALKGLIQQFTAITGASESVGKHMLEACNNNLEMAVTMFLDGGGIAEEPSTSSASVSAVRPHTEEEVRAPIPQKQEILVEPEPLFGVRQEQELRNGGAIDKKLTTLADLFRPPIDLMHKGSFETAKECGQMQNKWLMINIQNVQDFACQCLNRDVWSNEAVKNIIREHFIFWQVYHDSEEGQRYIQFYKLGDFPYVSILDPRTGQKLVEWHQLDVSSFLDQVTGFLGEHGQLDGLSSSPPKKCARSESLIDASEDSQLEAAIRASLQETHFDSAQAKQDSRSDEESESELFSGSEEFISVCGSDEEEEVENLAKSRKSPHKDLGHRKEENRRPMTEPPARTEPGTATNHQGMPAMDPEVLEMSPEKSDGIVEGIDVNGPKAQLMLRYPDGKREQITLPEQAKLLALVKHVQSKGYPNERFELLTNFPRRKLSHLDYDITLQEAGLCPQETVFVQERN", "length": 467, "header": "tr|A0A9J7JPH7-1|A0A8C2MX41_CRIGR Computationally mapped isoform of UBX domain-containing protein 7 OS=Cricetulus griseus OX=10029 GN=Ubxn7 PE=4 SV=1 CANONICAL=A0A8C2MX41-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JPH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPH7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JPH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPH7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761607", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761607", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "VCP-NPL4-UFD1 AAA ATPase complex", "id": "GO:0034098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034098", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX41", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX41", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX41", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX41", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX41", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX41", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX41", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MX41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX41" }, { "id": "PS50033", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBX", "eco_id": "ECO_0000259", "start_pos": 408, "end_pos": 485, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MX62-1", "uniprot_ac": "A0A8C2MX62", "uniprot_id": "A0A8C2MX62_CRIGR", "mass": { "chemical_mass": 9354.0, "monoisotopic_mass": 9354.0 }, "refseq": { "ac": "XP_003500868", "name": "V-type proton ATPase subunit e 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500868" }, "gene_names": [ { "name": "Atp6v0e1", "type": "recommended", "evidence": [ { "id": "A0A8C2MX62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX62" } ] }, { "name": "Atp6v0e1", "type": "synonym", "evidence": [ { "id": "XP_003500868", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500868" } ] } ], "protein_names": [ { "name": "V-type proton ATPase subunit", "type": "recommended", "evidence": [ { "id": "A0A8C2MX62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX62/entry#names_and_taxonomy" } ] }, { "name": "V-type proton ATPase subunit e 1", "type": "synonym", "evidence": [ { "id": "XP_003500868", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500868" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613815.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003500868", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500868" } ] }, { "annotation": "Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX62", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX62#function" }, { "database": "UniProtKB", "id": "ARBA00045818", "url": "https://www.uniprot.org/uniprotkb/ARBA00045818#function" }, { "database": "UniProtKB", "id": "PIRNR038097", "url": "https://www.uniprot.org/uniprotkb/PIRNR038097#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX62", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX62" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Atp6v0e1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX62", "locus": {} } ], "crossref": [ { "id": "100769759", "url": "https://www.ncbi.nlm.nih.gov/gene/100769759", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008389", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008389", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017385", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017385", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769759", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769759", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TDAIWYL", "url": "https://omabrowser.org/oma/group/TDAIWYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MX62", "url": "https://www.orthodb.org/?gene=A0A8C2MX62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12263", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12263", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12263:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12263:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003500868", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500868", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MX62", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MX62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAYHGLTVPLIVMSVFWGFVGLLVPWFIPKGPNRGVIITMLVTCSICCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP", "length": 81, "header": "tr|A0A8C2MX62-1|A0A8C2MX62_CRIGR Isoform 1 of V-type proton ATPase subunit OS=Cricetulus griseus OX=10029 GN=Atp6v0e1 PE=3 SV=1 CANONICAL=A0A8C2MX62-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MX62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX62/entry#A0A8C2MX62-1", "sequence": { "sequence": "MAYHGLTVPLIVMSVFWGFVGLLVPWFIPKGPNRGVIITMLVTCSICCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP", "length": 81, "header": "tr|A0A8C2MX62-1|A0A8C2MX62_CRIGR Isoform 1 of V-type proton ATPase subunit OS=Cricetulus griseus OX=10029 GN=Atp6v0e1 PE=3 SV=1 CANONICAL=A0A8C2MX62-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX62", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX62" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX62", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX62" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769759", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769759", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1U843-1", "protein_name": "V-type proton ATPase subunit", "gene_name": "ATP6V0E1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAYTGLTVPLIVMSVFWGFVGFLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP", "length": 81 }, "evidence": [ { "id": "A0A8C2MX62", "url": "https://omabrowser.org/oma/group/A0A8C2MX62/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P81103-1", "protein_name": "V-type proton ATPase subunit e 1", "gene_name": "ATP6V0E1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAYTGLTVPLIVMSVFWGIVGFLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP", "length": 81 }, "evidence": [ { "id": "A0A8C2MX62", "url": "https://omabrowser.org/oma/group/A0A8C2MX62/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CQD8-1", "protein_name": "V-type proton ATPase subunit e 1", "gene_name": "Atp6v0e1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAYHGLTVPLIVMSVFWGFVGLLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP", "length": 81 }, "evidence": [ { "id": "A0A8C2MX62", "url": "https://omabrowser.org/oma/group/A0A8C2MX62/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "proton-transporting V-type ATPase, V0 domain", "id": "GO:0033179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033179", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX62", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX62" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX62", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MX65-1", "uniprot_ac": "A0A8C2MX65", "uniprot_id": "A0A8C2MX65_CRIGR", "mass": { "chemical_mass": 70752.0, "monoisotopic_mass": 70752.0 }, "refseq": { "ac": "XP_003504066", "name": "zinc finger protein 189 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504066" }, "gene_names": [ { "name": "Znf189", "type": "recommended", "evidence": [ { "id": "A0A8C2MX65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65" } ] }, { "name": "Znf189", "type": "synonym", "evidence": [ { "id": "XP_003504066", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504066" } ] } ], "protein_names": [ { "name": "Zinc finger protein 189 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2MX65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 189 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003504066", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504066" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614021.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504066" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A9J7JEC7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JEC7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf189", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65", "locus": {} } ], "crossref": [ { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755468", "url": "https://www.ncbi.nlm.nih.gov/gene/100755468", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755468", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755468", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHISLIQ", "url": "https://omabrowser.org/oma/group/CHISLIQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MX65", "url": "https://www.orthodb.org/?gene=A0A8C2MX65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JEC7", "url": "https://www.orthodb.org/?gene=A0A9J7JEC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF66", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF66", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504066", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MX65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MX65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JEC7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JEC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JEC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JEC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPSPLLEPKEEWDYLDPTRRSLYKDVMMDSYGNMVSLDVLSKNKDEEPTVKEEIEEDIEPPGVIVTRIKSEIDQDPIATETFELVGRLDKQRGIFLWEIPRESLTQEQKMFRGHANVRKRPNSEEKCHKCEECGKGFARKAHFIQHQRVHTGEKPFQCNECGKSFSRSSFVIEHQRIHTGERPYECNYCGKTFSVSSTLIRHQRIHTGERPYQCNQCKQSFSQRRSLVKHQRIHTGEKPHKCSDCGKAFSWKSHLIEHQRTHTGEKPYHCTKCKKSFSRNSLLVEHQRIHTGERPHKCGECGKAFRLSTYLIQHQKIHTGEKPFLCIECGKSFSRSSFLIEHQRIHTGERPYQCKECGKSFSQLCNLTRHQRIHTGDKPHKCEECGKAFSRSSGLIQHQRIHIREKTSLYNETKESFDPNCSLVVQQEVCPKEKSYKCDECGKTFSVSAHLVQHQRTHTGEKPYLCTVCGKSFSRSSFLIEHQRIHTGERPYLCRQCGKSFSQLCNLIRHQGVHTGNKPHKCEECGKAFSRNSGLIQHQRIHTGEKPYRCEKCDKSFSQQRSLVNHQKIHTEVKKQEIYECDACGEAFNCQISLIQHQKLHIMWMQ", "length": 608, "header": "tr|A0A8C2MX65-1|A0A8C2MX65_CRIGR Isoform 1 of Zinc finger protein 189 isoform X1 OS=Cricetulus griseus OX=10029 GN=Znf189 PE=3 SV=1 CANONICAL=A0A8C2MX65-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MX65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65/entry#A0A8C2MX65-1", "sequence": { "sequence": "MASPSPLLEPKEEWDYLDPTRRSLYKDVMMDSYGNMVSLDVLSKNKDEEPTVKEEIEEDIEPPGVIVTRIKSEIDQDPIATETFELVGRLDKQRGIFLWEIPRESLTQEQKMFRGHANVRKRPNSEEKCHKCEECGKGFARKAHFIQHQRVHTGEKPFQCNECGKSFSRSSFVIEHQRIHTGERPYECNYCGKTFSVSSTLIRHQRIHTGERPYQCNQCKQSFSQRRSLVKHQRIHTGEKPHKCSDCGKAFSWKSHLIEHQRTHTGEKPYHCTKCKKSFSRNSLLVEHQRIHTGERPHKCGECGKAFRLSTYLIQHQKIHTGEKPFLCIECGKSFSRSSFLIEHQRIHTGERPYQCKECGKSFSQLCNLTRHQRIHTGDKPHKCEECGKAFSRSSGLIQHQRIHIREKTSLYNETKESFDPNCSLVVQQEVCPKEKSYKCDECGKTFSVSAHLVQHQRTHTGEKPYLCTVCGKSFSRSSFLIEHQRIHTGERPYLCRQCGKSFSQLCNLIRHQGVHTGNKPHKCEECGKAFSRNSGLIQHQRIHTGEKPYRCEKCDKSFSQQRSLVNHQKIHTEVKKQEIYECDACGEAFNCQISLIQHQKLHIMWMQ", "length": 608, "header": "tr|A0A8C2MX65-1|A0A8C2MX65_CRIGR Isoform 1 of Zinc finger protein 189 isoform X1 OS=Cricetulus griseus OX=10029 GN=Znf189 PE=3 SV=1 CANONICAL=A0A8C2MX65-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JEC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65/entry#A0A9J7JEC7-1", "sequence": { "sequence": "MASPSPLLEPKEWDYLDPTRRSLYKDVMMDSYGNMVSLDVLSKNKDEEPTVKEEIEEDIEPPGVIVTRIKSEIDQDPIATETFELVGRLDKQRGIFLWEIPRESLTQEQKMFRGHANVRKRPNSEEKCHKCEECGKGFARKAHFIQHQRVHTGEKPFQCNECGKSFSRSSFVIEHQRIHTGERPYECNYCGKTFSVSSTLIRHQRIHTGERPYQCNQCKQSFSQRRSLVKHQRIHTGEKPHKCSDCGKAFSWKSHLIEHQRTHTGEKPYHCTKCKKSFSRNSLLVEHQRIHTGERPHKCGECGKAFRLSTYLIQHQKIHTGEKPFLCIECGKSFSRSSFLIEHQRIHTGERPYQCKECGKSFSQLCNLTRHQRIHTGDKPHKCEECGKAFSRSSGLIQHQRIHIREKTSLYNETKESFDPNCSLVVQQEVCPKEKSYKCDECGKTFSVSAHLVQHQRTHTGEKPYLCTVCGKSFSRSSFLIEHQRIHTGERPYLCRQCGKSFSQLCNLIRHQGVHTGNKPHKCEECGKAFSRNSGLIQHQRIHTGEKPYRCEKCDKSFSQQRSLVNHQKIHTEVKKQEIYECDACGEAFNCQISLIQHQKLHIMWMQ", "length": 607, "header": "tr|A0A9J7JEC7-1|A0A9J7JEC7_CRIGR Computationally mapped isoform of Zinc finger protein 189 isoform X2 OS=Cricetulus griseus OX=10029 GN=Znf189 PE=3 SV=1 CANONICAL=A0A8C2MX65-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755468", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755468", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZRX1-1", "protein_name": "Zinc finger protein 189", "gene_name": "Zfp189", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASPSPPLESKEEWGYLDAAPRSLYKDVVMDSYGKLVSLDVLNRNEDEEPTVKEEIEKDIEPQGIIVTRIKSELDQDPMGSETFELVGRLDKQRGIFLWEIPRDSLTEEQKMFRGHTNVRKRPNSEEKCHKCEECGKRFVRKAHFIQHQRVHTGEKPFQCNECGKSFSRSSFVIEHQRIHTGERPYECNYCGKTFSVSSTLIRHQRIHTGERPYQCNQCKQSFSQRRSLVKHQRIHTGEKPHKCSDCGKAFSWKSHLIEHQRTHTGEKPYHCTKCKKSFSRNSLLVEHQRIHTGERPHKCGECGKAFRLSTYLIQHQKIHTGEKPFLCIECGKSFSRSSFLIEHQRIHTGERPYQCQECGKSFSQLCNLTRHQRIHTGDKPHKCEECGKAFSRSSGLIQHQRIHIREKTSPFKETKGSFDPNCGLVIQQEVYPKEKSYKCDDCGKTFSVSAHLVQHQRIHTGEKPYLCTVCGKSFSRSSFLIEHQRIHTGERPYLCRQCGKSFSQLCNLIRHQGVHTGNKPHKCEECGKAFSRNSGLIQHQRIHTGEKPYRCEKCDKSFSQQRSLVNHQKIHAEVKTQEIYECDACGEAFTCQISLIQHQKLHIMWMQ", "length": 608 }, "evidence": [ { "id": "A0A8C2MX65", "url": "https://omabrowser.org/oma/group/A0A8C2MX65/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75820-1", "protein_name": "Zinc finger protein 189", "gene_name": "ZNF189", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASPSPPPESKGLLTFEDVAVFFTQEEWDYLDPAQRSLYKDVMMENYGNLVSLDVLNRDKDEEPTVKQEIEEIEEEVEPQGVIVTRIKSEIDQDPMGRETFELVGRLDKQRGIFLWEIPRESLTQEQRMFRENTNIIRKRPNSEEKCHKCEECGKGFVRKAHFIQHQRVHTGEKPFQCNECGKSFSRSSFVIEHQRIHTGERPYECNYCGKTFSVSSTLIRHQRIHTGERPYQCNQCKQSFSQRRSLVKHQRIHTGEKPHKCSDCGKAFSWKSHLIEHQRTHTGEKPYHCTKCKKSFSRNSLLVEHQRIHTGERPHKCGECGKAFRLSTYLIQHQKIHTGEKPFLCIECGKSFSRSSFLIEHQRIHTGERPYQCKECGKSFSQLCNLTRHQRIHTGDKPHKCEECGKAFSRSSGLIQHQRIHTREKTYPYNETKESFDPNCSLVIQQEVYPKEKSYKCDECGKTFSVSAHLVQHQRIHTGEKPYLCTVCGKSFSRSSFLIEHQRIHTGERPYLCRQCGKSFSQLCNLIRHQGVHTGNKPHKCDECGKAFSRNSGLIQHQRIHTGEKPYKCEKCDKSFSQQRSLVNHQKIHAEVKTQETHECDACGEAFNCRISLIQHQKLHTAWMQ", "length": 626 }, "evidence": [ { "id": "A0A8C2MX65", "url": "https://omabrowser.org/oma/group/A0A8C2MX65/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear lumen", "id": "GO:0031981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031981", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65" } ], "pmid": "" }, { "name": "positive regulation of biosynthetic process", "id": "GO:0009891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009891", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MX65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 130, "end_pos": 157, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MX65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX65" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 75, "start_aa": "Met", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 368, "end_pos": 370 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 422, "end_pos": 424 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MXE8-1", "uniprot_ac": "A0A8C2MXE8", "uniprot_id": "A0A8C2MXE8_CRIGR", "mass": { "chemical_mass": 86219.0, "monoisotopic_mass": 86219.0 }, "refseq": { "ac": "XP_003508037", "name": "ribosome-releasing factor 2, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508037" }, "gene_names": [ { "name": "Gfm2", "type": "recommended", "evidence": [ { "id": "A0A8C2MXE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8" } ] }, { "name": "EFG2", "type": "synonym", "evidence": [ { "id": "A0A8C2MXE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8" } ] }, { "name": "GFM2", "type": "synonym", "evidence": [ { "id": "A0A8C2MXE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8" } ] }, { "name": "Gfm2", "type": "synonym", "evidence": [ { "id": "XP_003508037", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508037" } ] } ], "protein_names": [ { "name": "Ribosome-releasing factor 2, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8C2MXE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8/entry#names_and_taxonomy" } ] }, { "name": "EF-G2mt", "type": "synonym", "evidence": [ { "id": "A0A8C2MXE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8/entry#names_and_taxonomy" } ] }, { "name": "Elongation factor G 2, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A8C2MXE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8/entry#names_and_taxonomy" } ] }, { "name": "RRF2mt", "type": "synonym", "evidence": [ { "id": "A0A8C2MXE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8/entry#names_and_taxonomy" } ] }, { "name": "mEF-G 2", "type": "synonym", "evidence": [ { "id": "A0A8C2MXE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8/entry#names_and_taxonomy" } ] }, { "name": "ribosome-releasing factor 2, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003508037", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508037" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614466.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003508037", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508037" } ] }, { "annotation": "Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FIH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIH9#function" }, { "database": "HAMAP", "id": "MF_03059", "url": "https://hamap.expasy.org/signature/MF_03059" }, { "database": "UniProtKB", "id": "A0A8C2MXE8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8#function" }, { "database": "UniProtKB", "id": "A0A9J7JDE6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDE6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXE8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gfm2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8", "locus": {} } ], "crossref": [ { "id": "cd01693", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01693", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01886", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01886", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03713", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03713", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04092", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04092", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16262", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16262", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755195", "url": "https://www.ncbi.nlm.nih.gov/gene/100755195", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009022", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009022", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053905", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053905", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755195", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755195", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MXE8", "url": "https://www.orthodb.org/?gene=A0A8C2MXE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43261", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43261", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43261:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43261:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00009", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00009", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03764", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03764", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22042", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22042", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003508037", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508037", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MXE8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MXE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FDH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FDH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FIH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FIH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JDE6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JDE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFISWRIFAMNHQRIFSVHFKTMCYCKIKAILKRSKTPVPLRRNYSSPPGVVGNDVKSLYSIISPPVAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWKQADKHKIPRICFLNKMDKTGASFNYAVESIREKLKVKPLLLQLPIGEARTFKGVIDVVNKEKLVWNSNSDDGKDFERKPLLETSDLELLKEAIEARNSLIEQVADLDDEFADLVLEEFSENFDLVPAEKLQTAIHRVTLAQAAVPVLCGSALKNKGVQPLLDAITMYLPSPEEREYGFLQWYKGDLCALAFKVLHDKQRGPLVFLRIYSGTLTPQLAIHNINRNCTERMSRLLLPFADQHVEIPSLTAGNIALTVGLKQTATGDTIVSSKSSALAAARRAGRGEKKPGKNSETESLLLAGVEIPEPVFFCTIEPPSVAKQPDLDHALERLQREDPSLKVRLDPDSGQTVLCGMGELHIEIIHDRIKREYGLDTYLGPLQVAYRETILNSVRATDTLDRTLGDKRHFVRAELEARPVEASSGMAVIEYADCISVDLLQASREAIENAVHSACLQGPLLGSPVQDVAITLHSLMIHPGTSTTMVNACVSRCIQKALKKADKQVLEPLMSLEVTVTGDYLSPVLADLAQRRGNVQEIQTRQDNKVVIGFVPLAEMMGYSTVLRTLTSGSATFALEFSTYQAMSPQDQSTLLTQRSGLAHVL", "length": 779, "header": "tr|A0A8C2MXE8-1|A0A8C2MXE8_CRIGR Isoform 1 of Ribosome-releasing factor 2, mitochondrial OS=Cricetulus griseus OX=10029 GN=Gfm2 PE=3 SV=1 CANONICAL=A0A8C2MXE8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MXE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8/entry#A0A8C2MXE8-1", "sequence": { "sequence": "MFISWRIFAMNHQRIFSVHFKTMCYCKIKAILKRSKTPVPLRRNYSSPPGVVGNDVKSLYSIISPPVAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWKQADKHKIPRICFLNKMDKTGASFNYAVESIREKLKVKPLLLQLPIGEARTFKGVIDVVNKEKLVWNSNSDDGKDFERKPLLETSDLELLKEAIEARNSLIEQVADLDDEFADLVLEEFSENFDLVPAEKLQTAIHRVTLAQAAVPVLCGSALKNKGVQPLLDAITMYLPSPEEREYGFLQWYKGDLCALAFKVLHDKQRGPLVFLRIYSGTLTPQLAIHNINRNCTERMSRLLLPFADQHVEIPSLTAGNIALTVGLKQTATGDTIVSSKSSALAAARRAGRGEKKPGKNSETESLLLAGVEIPEPVFFCTIEPPSVAKQPDLDHALERLQREDPSLKVRLDPDSGQTVLCGMGELHIEIIHDRIKREYGLDTYLGPLQVAYRETILNSVRATDTLDRTLGDKRHFVRAELEARPVEASSGMAVIEYADCISVDLLQASREAIENAVHSACLQGPLLGSPVQDVAITLHSLMIHPGTSTTMVNACVSRCIQKALKKADKQVLEPLMSLEVTVTGDYLSPVLADLAQRRGNVQEIQTRQDNKVVIGFVPLAEMMGYSTVLRTLTSGSATFALEFSTYQAMSPQDQSTLLTQRSGLAHVL", "length": 779, "header": "tr|A0A8C2MXE8-1|A0A8C2MXE8_CRIGR Isoform 1 of Ribosome-releasing factor 2, mitochondrial OS=Cricetulus griseus OX=10029 GN=Gfm2 PE=3 SV=1 CANONICAL=A0A8C2MXE8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FDH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8/entry#A0A9J7FDH3-1", "sequence": { "sequence": "MFISWRIFAMNHQRIFSVHFKTMCYCKIKAILKRSKTPVPLRRNYSSPPGVVGNDVKSLYSIISPPVAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWKQADKHKIPRICFLNKMDKTGASFNYAVESIREKLKVKPLLLQLPIGEARTFKGVIDVVNKEKLVWNSNSDDGKDFERKPLLETSDLELLKEAIEARNSLIEQVADLDDEFADLVLEEFSENFDLVPAEKLQTAIHRVTLAQAAVPVLCGSALKNKGVQPLLDAITMYLPSPEEREYGFLQWYKGDLCALAFKVLHDKQRGPLVFLRIYSGTLTPQLAIHNINRNCTERMSRLLLPFADQHVEIPSLTAGNIALTVGLKQTATGDTIVSSKSSALAAARRAGRGEKKPGKNSETESLLLAGVEIPEPVFFCTIEPPSVAKQPDTLDRTLGDKRHFVRAELEARPVEASSGMAVIEYADCISVDLLQASREAIENAVHSACLQGPLLGSPVQDVAITLHSLMIHPGTSTTMVNACVSRCIQKALKKADKQVLEPLMSLEVTVTGDYLSPVLADLAQRRGNVQEIQTRQDNKVVIGFVPLAEMMGYSTVLRTLTSGSATFALEFSTYQAMSPQDQSTLLTQRSGLAHVL", "length": 707, "header": "tr|A0A9J7FDH3-1|A0A8C2MXE8_CRIGR Computationally mapped isoform of Ribosome-releasing factor 2, mitochondrial OS=Cricetulus griseus OX=10029 GN=Gfm2 PE=3 SV=1 CANONICAL=A0A8C2MXE8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FIH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8/entry#A0A9J7FIH9-1", "sequence": { "sequence": "MFISWRIFAMNHQRIFSVHFKTMCYCKIKAILKRSKTPVPLRRNYSSPPGVVGNDVKSLYSIISPPVAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWKQADKHKIPRICFLNKMDKTGASFNYAVESIREKLKVKPLLLQLPIGEARTFKGVIDVVNKEKLVWNSNSDDGKDFERKPLLETSDLELLKEAIEARNSLIEQVADLDDEFADLVLEEFSENFDLVPAEKLQTAIHRVTLAQAAVPVLCGSALKNKGVQPLLDAITMYLPSPEEREYGFLQWYKGDLCALAFKVLHDKQRGPLVFLRIYSGTLTPQLAIHNINRNCTERMSRLLLPFADQHVEIPSLTAGNIALTVGLKQTATGDTIVSSKSSALAAARRAGRGEKKPGKNSETESLLLAGVEIPEPVFFCTIEPPSVAKQPDLDHALERLQREDPSLKVRLDPDSGQTVLCGMGELHIEIIHDRIKREYGLDTYLGPLQVAYRETILNSVRATDTLDRTLGDKRHFVRAELEARPVEASSGMAVIEYADCISVDLLQASREAIENAVHSACLQGPLLGSPVQDVAITLHSLMIHPGTSTTMVNACVSRCIQKALKKADKQVLEPLMSLEVTVTGDYLSPVLADLAQRRGNVQEIQTRQDNKVVIGFVPLAEMMGYSTVLRTLTSGSATFALEFSTYQAMSPQDQSTLLTQRSGLAHVL", "length": 737, "header": "tr|A0A9J7FIH9-1|A0A8C2MXE8_CRIGR Computationally mapped isoform of Ribosome-releasing factor 2, mitochondrial OS=Cricetulus griseus OX=10029 GN=Gfm2 PE=3 SV=1 CANONICAL=A0A8C2MXE8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JDE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8/entry#A0A9J7JDE6-1", "sequence": { "sequence": "MAQERERGITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWKQADKHKIPRICFLNKMDKTGASFNYAVESIREKLKVKPLLLQLPIGEARTFKGVIDVVNKEKLVWNSNSDDGKDFERKPLLETSDLELLKEAIEARNSLIEQVADLDDEFADLVLEEFSENFDLVPAEKLQTAIHRVTLAQAAVPVLCGSALKNKGVQPLLDAITMYLPSPEEREYGFLQWYKGDLCALAFKVLHDKQRGPLVFLRIYSGTLTPQLAIHNINRNCTERMSRLLLPFADQHVEIPSLTAGNIALTVGLKQTATGDTIVSSKSSALAAARRAGRGEKKPGKNSETESLLLAGVEIPEPVFFCTIEPPSVAKQPDLDHALERLQREDPSLKVRLDPDSGQTVLCGMGELHIEIIHDRIKREYGLDTYLGPLQVAYRETILNSVRATDTLDRTLGDKRHFVRAELEARPVEASSGMAVIEYADCISVDLLQASREAIENAVHSACLQGPLLGSPVQDVAITLHSLMIHPGTSTTMVNACVSRCIQKALKKADKQVLEPLMSLEVTVTGDYLSPVLADLAQRRGNVQEIQTRQDNKVVIGFVPLAEMMGYSTVLRTLTSGSATFALEFSTYQAMSPQDQSTLLTQRSGLAHVL", "length": 667, "header": "tr|A0A9J7JDE6-1|A0A9J7JDE6_CRIGR Computationally mapped isoform of Ribosome-releasing factor 2, mitochondrial OS=Cricetulus griseus OX=10029 GN=Gfm2 PE=3 SV=1 CANONICAL=A0A8C2MXE8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FIH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIH9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FIH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIH9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755195", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755195", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ribosome disassembly", "id": "GO:0032790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032790", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXE8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8" } ], "pmid": "" }, { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXE8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXE8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXE8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXE8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRJ8-1", "G3GY22-1", "G3H2D6-1", "G3HID1-1", "A0A9J7FY79-1", "G3IBI0-1", "G3HIM4-1", "G3HLW5-1", "G3I0B0-1", "G3H8L7-1", "G3IMU0-1", "G3HQ45-1", "G3HX83-1", "G3H515-1", "G3HRK4-1", "G3HWS3-1", "G3I185-1", "G3I2E9-1", "G3IHJ9-1", "G3I5Q9-1", "G3H3P1-1", "G3HGA7-1", "A0A9J7K0Q7-1", "G3I8B8-1", "A0A9J7FPY4-1", "A0A9J7JNI7-1", "A0A9J7JTM0-1", "G3HXK0-1", "G3I1T6-1", "A0A8C2M8V3-1", "G3HAT4-1", "G3HBU1-1", "A0A8C2MG78-1", "A0A9J7JFJ5-1", "A0A061I5F7-1", "A0A9J7GMX4-1", "G3H3X0-1", "A0A8C2MG41-1", "A0A8C2MJU2-1", "A0A8C2MKJ3-1", "A0A8C2QMP3-1", "A0A9J7F720-1", "A0A061IFE4-1", "A0A061HZZ7-1", 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}, { "id": "A0A9J7K5V2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5V2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K605", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K605", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K605-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K605-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K610", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K610", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K610-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K610-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K615", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K615", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K615-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K615-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEEVQEEAPEPEEVQEDAVAEEEQEEDEEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 272, "header": "tr|A0A8C2MXE9-1|A0A8C2MXE9_CRIGR Isoform 1 of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MXE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A8C2MXE9-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEEVQEEAPEPEEVQEDAVAEEEQEEDEEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 272, "header": "tr|A0A8C2MXE9-1|A0A8C2MXE9_CRIGR Isoform 1 of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N0C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A8C2N0C0-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEEVQEEEEVQEDAVAEEEQEEDEEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 268, "header": "tr|A0A8C2N0C0-1|A0A8C2N0C0_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N0E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A8C2N0E0-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEEVQEEAPEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 254, "header": "tr|A0A8C2N0E0-1|A0A8C2N0E0_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N1B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A8C2N1B3-1", "sequence": { "sequence": "MSDEETEQVEEEAQEEEVQEEEEVQEDAVAEEEQEEDEEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 262, "header": "tr|A0A8C2N1B3-1|A0A8C2N1B3_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N1C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A8C2N1C5-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEEVQEEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 259, "header": "tr|A0A8C2N1C5-1|A0A8C2N1C5_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A8C2QNF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A8C2QNF3-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEEEVQEDAVAEEEQEEDEEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 263, "header": "tr|A0A8C2QNF3-1|A0A8C2MXE9_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A8C2QNU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A8C2QNU7-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEEVQEEAPEPEEVQEDAVAEEEQEEDEEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 272, "header": "tr|A0A8C2QNU7-1|A0A8C2MXE9_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FNZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7FNZ1-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEDAVAEEEQEEDEEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 258, "header": "tr|A0A9J7FNZ1-1|A0A8C2MXE9_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GQG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GQG2-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEAAEVQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 257, "header": "tr|A0A9J7GQG2-1|A0A9J7GQG2_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GQH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GQH2-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEAPEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 249, "header": "tr|A0A9J7GQH2-1|A0A9J7GQH2_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GQI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GQI0-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 245, "header": "tr|A0A9J7GQI0-1|A0A9J7GQI0_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GR37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GR37-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEVQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 249, "header": "tr|A0A9J7GR37-1|A0A9J7GR37_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GR46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GR46-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 245, "header": "tr|A0A9J7GR46-1|A0A9J7GR46_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GRZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GRZ2-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEEVQEEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 259, "header": "tr|A0A9J7GRZ2-1|A0A9J7GRZ2_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GRZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GRZ7-1", "sequence": { "sequence": "MSDEETEQVEEEAQEEEVQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 249, "header": "tr|A0A9J7GRZ7-1|A0A9J7GRZ7_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GS05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GS05-1", "sequence": { "sequence": "MSDEETEQVEEEAQEEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 248, "header": "tr|A0A9J7GS05-1|A0A9J7GS05_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GS06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GS06-1", "sequence": { "sequence": "MSDEETEQVEEVQEEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 247, "header": "tr|A0A9J7GS06-1|A0A9J7GS06_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GS13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GS13-1", "sequence": { "sequence": "MSDEETEQVEEVQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 243, "header": "tr|A0A9J7GS13-1|A0A9J7GS13_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GSU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GSU7-1", "sequence": { "sequence": "MSDEETEQVEEEAQEEEVQEEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 253, "header": "tr|A0A9J7GSU7-1|A0A9J7GSU7_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GSV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GSV6-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEVQEEAPEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 248, "header": "tr|A0A9J7GSV6-1|A0A9J7GSV6_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GSW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GSW5-1", "sequence": { "sequence": "MSDEETEQVEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 242, "header": "tr|A0A9J7GSW5-1|A0A9J7GSW5_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GSZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GSZ3-1", "sequence": { "sequence": "MSDEETEQVEEEAQEEEVQEEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 253, "header": "tr|A0A9J7GSZ3-1|A0A9J7GSZ3_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GT01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GT01-1", "sequence": { "sequence": "MSDEETEQVEEEAQEEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 248, "header": "tr|A0A9J7GT01-1|A0A9J7GT01_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GT10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GT10-1", "sequence": { "sequence": "MSDEETEQVEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 242, "header": "tr|A0A9J7GT10-1|A0A9J7GT10_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GU56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GU56-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEEVQEEAPEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 254, "header": "tr|A0A9J7GU56-1|A0A9J7GU56_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GU66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GU66-1", "sequence": { "sequence": "MSDEETEQVEEEAQEEEVQEEAPEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 248, "header": "tr|A0A9J7GU66-1|A0A9J7GU66_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GU76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GU76-1", "sequence": { "sequence": "MSDEETEQVEEEAQEEAPEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 243, "header": "tr|A0A9J7GU76-1|A0A9J7GU76_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GUF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GUF8-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 254, "header": "tr|A0A9J7GUF8-1|A0A9J7GUF8_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GUG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GUG7-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEVQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 249, "header": "tr|A0A9J7GUG7-1|A0A9J7GUG7_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GUH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GUH7-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEAPEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 243, "header": "tr|A0A9J7GUH7-1|A0A9J7GUH7_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GVP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GVP5-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEEVQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 255, "header": "tr|A0A9J7GVP5-1|A0A9J7GVP5_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GVQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GVQ5-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEAPEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 249, "header": "tr|A0A9J7GVQ5-1|A0A9J7GVQ5_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GVR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GVR4-1", "sequence": { "sequence": "MSDEETEQVEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 244, "header": "tr|A0A9J7GVR4-1|A0A9J7GVR4_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GW39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GW39-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 254, "header": "tr|A0A9J7GW39-1|A0A9J7GW39_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GW50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GW50-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 248, "header": "tr|A0A9J7GW50-1|A0A9J7GW50_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GW60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7GW60-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEAPEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 243, "header": "tr|A0A9J7GW60-1|A0A9J7GW60_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7JKA8-1", "sequence": { "sequence": "MSDEETEQVEEEAQEEEEVQEDAVAEEEQEEDEEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 257, "header": "tr|A0A9J7JKA8-1|A0A8C2MXE9_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JVM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7JVM1-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEVQEEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 253, "header": "tr|A0A9J7JVM1-1|A0A8C2MXE9_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JVM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7JVM4-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEVQEEAPEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 248, "header": "tr|A0A9J7JVM4-1|A0A8C2MXE9_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JVM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7JVM7-1", "sequence": { "sequence": "MSDEETEQVEEVQEEAPEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 242, "header": "tr|A0A9J7JVM7-1|A0A8C2MXE9_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K2L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7K2L7-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEVQEEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 253, "header": "tr|A0A9J7K2L7-1|A0A8C2MXE9_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K2M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7K2M2-1", "sequence": { "sequence": "MSDEETEQVEEEAQEEEVQEEAPEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 248, "header": "tr|A0A9J7K2M2-1|A0A8C2MXE9_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K2M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7K2M5-1", "sequence": { "sequence": "MSDEETEQVEEVQEEAPEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 242, "header": "tr|A0A9J7K2M5-1|A0A8C2MXE9_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K4E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7K4E4-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 250, "header": "tr|A0A9J7K4E4-1|A0A8C2MXE9_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K4F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7K4F0-1", "sequence": { "sequence": "MSDEETEQVEEVQEEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 247, "header": "tr|A0A9J7K4F0-1|A0A8C2MXE9_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K5U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7K5U8-1", "sequence": { "sequence": 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griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K605-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7K605-1", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEEVQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 255, "header": "tr|A0A9J7K605-1|A0A8C2MXE9_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K610-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7K610-1", "sequence": { "sequence": "MSDEETEQVEEEAQEEEVQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDIMTVRARVEMLAKFSKKAGATAKGKVGGRWK", "length": 249, "header": "tr|A0A9J7K610-1|A0A8C2MXE9_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K615-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9/entry#A0A9J7K615-1", "sequence": { "sequence": "MSDEETEQVEEEAQEEAPEPEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 243, "header": "tr|A0A9J7K615-1|A0A8C2MXE9_CRIGR Computationally mapped isoform of Troponin T, fast skeletal muscle OS=Cricetulus griseus OX=10029 GN=Tnnt3 PE=3 SV=1 CANONICAL=A0A8C2MXE9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNF3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNF3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767498", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767498", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P09739-1", "protein_name": "Troponin T, fast skeletal muscle", "gene_name": "Tnnt3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDEETEQVEEQYEEEEEAQEEEVQEEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK", "length": 259 }, "evidence": [ { "id": "A0A8C2MXE9", "url": "https://omabrowser.org/oma/group/A0A8C2MXE9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P45378-1", "protein_name": "Troponin T, fast skeletal muscle", "gene_name": "TNNT3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGTPAKGKVGGRWK", "length": 269 }, "evidence": [ { "id": "A0A8C2MXE9", "url": "https://omabrowser.org/oma/group/A0A8C2MXE9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q75NG9-1", "protein_name": "Troponin T, fast skeletal muscle", "gene_name": "TNNT3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSDEEVEHVEEEYEEEEEAQEEAPPPPAEVHEVHEEVHEVHEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEEAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKVLAERRKPLNIDHLSEDKLRDKAKELWDALYQLEIDKFEYGEKLKRQKYDIINLRSRIDQAQKHSKKAGTTPKGKVGGRWK", "length": 271 }, "evidence": [ { "id": "A0A8C2MXE9", "url": "https://omabrowser.org/oma/group/A0A8C2MXE9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "troponin C binding", "id": "GO:0030172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030172", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXE9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXE9" } ], "pmid": "" }, { "name": "tropomyosin binding", "id": "GO:0005523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005523", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXE9", "url": 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"title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H2X3-1", "uniprot_ac": "A0A9J7H2X3", "uniprot_id": "A0A9J7H2X3_CRIGR", "mass": { "chemical_mass": 29511.0, "monoisotopic_mass": 29511.0 }, "refseq": { "ac": "XP_035303931", "name": "collectin-11 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303931" }, "gene_names": [ { "name": "Colec11", "type": "recommended", "evidence": [ { "id": "A0A9J7H2X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X3" } ] }, { "name": "Colec11", "type": "synonym", "evidence": [ { "id": "XP_035303931", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303931" } ] } ], "protein_names": [ { "name": "Collectin-11", "type": "recommended", "evidence": [ { "id": "A0A9J7H2X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X3/entry#names_and_taxonomy" } ] }, { "name": "collectin-11 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035303931", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303931" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303931", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303931" } ] }, { "annotation": "Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding. Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M7U4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7U4#function" }, { "database": "UniProtKB", "id": "ARBA00045618", "url": "https://www.uniprot.org/uniprotkb/ARBA00045618#function" }, { "database": "UniProtKB", "id": "A0A9J7H2X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X3#function" }, { "database": "UniProtKB", "id": "A0A9J7H6J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6J3#function" }, { "database": "UniProtKB", "id": "A0A9J7H1R6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1R6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2X3", "url": 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}, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051663", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051663", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765657", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765657", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ITMYFLC", "url": "https://omabrowser.org/oma/group/ITMYFLC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H2X3", "url": "https://www.orthodb.org/?gene=A0A9J7H2X3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22799", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22799", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22799:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22799:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24024:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24024:SF14", "database": "PANTHER", "categories": [ "Protein 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] }, { "id": "A0A9J7H2X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6J3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBW7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBW7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMTRDLALAGMLISLAFLSLLPSGCPQQTTEDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGTVGRHGKIGPIGAKGEKGDSGDIGPPGPSGEPGIPCECSQLRKAIGEMDNQVTQLTTELKFIKNALPSPAAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAANGLMASYLAQAGLARVFIGINDLEKEGDFVYSDRSPMQTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHITMYFMCEFDKENL", "length": 278, "header": "tr|A0A9J7H2X3-1|A0A9J7H2X3_CRIGR Isoform 1 of Collectin-11 OS=Cricetulus griseus OX=10029 GN=Colec11 PE=3 SV=1 CANONICAL=A0A9J7H2X3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M7U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X3/entry#A0A8C2M7U4-1", "sequence": { "sequence": "MMTRDLALAGMLISLAFLSLLPSGCPQQTTEDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGTVGRHGKIGPIGAKGEKGDSGDIGPPGPSGEPGIPCECSQLRKAIGEMDNQVTQLTTELKFIKNAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAANGLMASYLAQAGLARVFIGINDLEKEGDFVYSDRSPMQTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHITMYFMCEFDKENL", "length": 272, "header": "tr|A0A8C2M7U4-1|A0A9J7H2X3_CRIGR Computationally mapped isoform of Collectin-11 OS=Cricetulus griseus OX=10029 GN=Colec11 PE=3 SV=1 CANONICAL=A0A9J7H2X3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X3/entry#A0A9J7H1R6-1", "sequence": { "sequence": "MTRDLALAGMLISLAFLSLLPSGCPQQTTEDACSVQILVPGLKGDMGDKGQKGTVGRHGKIGPIGAKGEKGDSGDIGPPGPSGEPGIPCECSQLRKAIGEMDNQVTQLTTELKFIKNAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAANGLMASYLAQAGLARVFIGINDLEKEGDFVYSDRSPMQTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHITMYFMCEFDKENL", "length": 247, "header": "tr|A0A9J7H1R6-1|A0A9J7H1R6_CRIGR Computationally mapped isoform of Collectin-11 OS=Cricetulus griseus OX=10029 GN=Colec11 PE=3 SV=1 CANONICAL=A0A9J7H2X3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X3/entry#A0A9J7H2X3-1", "sequence": { "sequence": "MMTRDLALAGMLISLAFLSLLPSGCPQQTTEDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGTVGRHGKIGPIGAKGEKGDSGDIGPPGPSGEPGIPCECSQLRKAIGEMDNQVTQLTTELKFIKNALPSPAAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAANGLMASYLAQAGLARVFIGINDLEKEGDFVYSDRSPMQTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHITMYFMCEFDKENL", "length": 278, "header": "tr|A0A9J7H2X3-1|A0A9J7H2X3_CRIGR Isoform 1 of Collectin-11 OS=Cricetulus griseus OX=10029 GN=Colec11 PE=3 SV=1 CANONICAL=A0A9J7H2X3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H6J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X3/entry#A0A9J7H6J3-1", "sequence": { "sequence": "MTRDLALAGMLISLAFLSLLPSGCPQQTTEDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGEKGDSGDIGPPGPSGEPGIPCECSQLRKAIGEMDNQVTQLTTELKFIKNAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAANGLMASYLAQAGLARVFIGINDLEKEGDFVYSDRSPMQTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHITMYFMCEFDKENL", "length": 247, "header": "tr|A0A9J7H6J3-1|A0A9J7H6J3_CRIGR Computationally mapped isoform of Collectin-11 OS=Cricetulus griseus OX=10029 GN=Colec11 PE=3 SV=1 CANONICAL=A0A9J7H2X3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X3/entry#A0A9J7KBW7-1", "sequence": { "sequence": "MTRDLALAGMLISLAFLSLLPSGCPQQTTEDACSVQILVPGLKGEKGDSGDIGPPGPSGEPGIPCECSQLRKAIGEMDNQVTQLTTELKFIKNAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAANGLMASYLAQAGLARVFIGINDLEKEGDFVYSDRSPMQTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHITMYFMCEFDKENL", "length": 223, "header": "tr|A0A9J7KBW7-1|A0A9J7H2X3_CRIGR Computationally mapped isoform of Collectin-11 OS=Cricetulus griseus OX=10029 GN=Colec11 PE=3 SV=1 CANONICAL=A0A9J7H2X3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 65, "start_aa": "Thr", "end_pos": 65, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr65", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M7U4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7U4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M7U4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7U4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765657", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765657", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q17QH6-1", "protein_name": "Collectin-11", "gene_name": "COLEC11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKRALALMGLAFLCVLRAGAAQQTVDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDVGDKGQKGGVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGIPCECSQLRKAIGEMDNQVTQLTAELKFIKNAVAGVRETEQKMYLLVKEEKRYLDAQLACQGRGGTLSMPKDEAANALLAAYITQAGLARVFIGINDLEREGAFVYADRSPMQTFSKWRSGEPNNAYDEEDCVELVASGGWNDVACHLTMHFLCEFDKEHV", "length": 267 }, "evidence": [ { "id": "A0A9J7H2X3", "url": "https://omabrowser.org/oma/group/A0A9J7H2X3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3SXB8-1", "protein_name": "Collectin-11", "gene_name": "Colec11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMMRDLALAGMLISLAFLSLLPSGCPQQTTEDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGTVGRHGKIGPIGAKGEKGDSGDIGPPGPSGEPGIPCECSQLRKAIGEMDNQVTQLTTELKFIKNAVAGLRETESKIYLLVKEEKRYADAQLSCQARGGTLSMPKDEAANGLMASYLAQAGLARVFIGINDLEKEGAFVYSDRSPMQTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHITMYFMCEFDKENL", "length": 272 }, "evidence": [ { "id": "A0A9J7H2X3", "url": "https://omabrowser.org/oma/group/A0A9J7H2X3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BWP8-1", "protein_name": "Collectin-11", "gene_name": "COLEC11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGNLALVGVLISLAFLSLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCECSQLRKAIGEMDNQVSQLTSELKFIKNAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAANGLMAAYLAQAGLARVFIGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHTTMYFMCEFDKENM", "length": 271 }, "evidence": [ { "id": "A0A9J7H2X3", "url": "https://omabrowser.org/oma/group/A0A9J7H2X3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "oligosaccharide binding", "id": "GO:0070492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070492", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X3" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2X3", "url": 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{ "database": "UniProtKB", "id": "A0A9J7H2X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X3" } ], "pmid": "" }, { "name": "antimicrobial humoral response", "id": "GO:0019730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X3" } ], "pmid": "" }, { "name": "complement activation, lectin pathway", "id": "GO:0001867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001867", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X3" } ], "pmid": "" }, { "name": "positive regulation of opsonization", "id": "GO:1903028", 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N5K5-1", "uniprot_ac": "A0A8C2N5K5", "uniprot_id": "A0A8C2N5K5_CRIGR", "mass": { "chemical_mass": 45817.0, "monoisotopic_mass": 45817.0 }, "refseq": { "ac": "XP_007643489", "name": "ceramide synthase 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643489" }, "gene_names": [ { "name": "Cers6", "type": "recommended", "evidence": [ { "id": "A0A8C2N5K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5K5" } ] }, { "name": "Cers6", "type": "synonym", "evidence": [ { "id": "XP_007643489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643489" } ] } ], "protein_names": [ { "name": "Ceramide synthase 6 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2N5K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5K5/entry#names_and_taxonomy" } ] }, { "name": "ceramide synthase 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007643489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643489" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 142 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613606.1) and transcript sequence (IACG01048577.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007643489", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643489" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5K5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5K5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cers6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5K5", "locus": {} } ], "crossref": [ { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761613", "url": "https://www.ncbi.nlm.nih.gov/gene/100761613", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761613", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761613", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YLIGAPY", "url": "https://omabrowser.org/oma/group/YLIGAPY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N5K5", "url": "https://www.orthodb.org/?gene=A0A8C2N5K5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12560", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12560", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12560:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12560:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007643489", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643489", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36547", "url": "https://www.rhea-db.org/rhea/36547", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N5K5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5K5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N5K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5K5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3GU80", "url": "https://www.uniprot.org/uniprotkb/G3GU80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3GU80-1", "url": "https://www.uniprot.org/uniprotkb/G3GU80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPVAFCIFMVRLIFERFIAKPCAIALNIQASGPQIAQPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTRFCESMWRFSFYLYVFIYGVRFLKQTPWLWNTRHCWYNYPYQPLTADLHYYYILELSFYWSLMVSQFTDIKRKDFGIMFLHHLASIFLLSFSYVNNMARVGTLVLCLHDSADALLEAAKMANYAKFQKMCDLLFVMFAMVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFNLLLLLVQGLNCFWSYLIVKIAWKAVSKGKAGKWNPLHVSKDDRSDIESSSEDEDSEPPGKKPHTSTTTNGTSGTNGYLLTGPCSMDD", "length": 392, "header": "tr|A0A8C2N5K5-1|A0A8C2N5K5_CRIGR Isoform 1 of Ceramide synthase 6 isoform X1 OS=Cricetulus griseus OX=10029 GN=Cers6 PE=3 SV=1 CANONICAL=A0A8C2N5K5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N5K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5K5/entry#A0A8C2N5K5-1", "sequence": { "sequence": "MAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPVAFCIFMVRLIFERFIAKPCAIALNIQASGPQIAQPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTRFCESMWRFSFYLYVFIYGVRFLKQTPWLWNTRHCWYNYPYQPLTADLHYYYILELSFYWSLMVSQFTDIKRKDFGIMFLHHLASIFLLSFSYVNNMARVGTLVLCLHDSADALLEAAKMANYAKFQKMCDLLFVMFAMVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFNLLLLLVQGLNCFWSYLIVKIAWKAVSKGKAGKWNPLHVSKDDRSDIESSSEDEDSEPPGKKPHTSTTTNGTSGTNGYLLTGPCSMDD", "length": 392, "header": "tr|A0A8C2N5K5-1|A0A8C2N5K5_CRIGR Isoform 1 of Ceramide synthase 6 isoform X1 OS=Cricetulus griseus OX=10029 GN=Cers6 PE=3 SV=1 CANONICAL=A0A8C2N5K5-1" }, "locus": {} }, { "isoform_ac": "G3GU80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5K5/entry#G3GU80-1", "sequence": { "sequence": "MAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPVAFCIFMVRLIFERFIAKPCAIALNIQASGPQIAQPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTRFCESMWRFSFYLYVFIYGVRFLKQTPWLWNTRHCWYNYPYQPLTADLHYYYILELSFYWSLMVSQFTDIKRKDFGIMFLHHLASIFLLSFSYVNNMARVGTLVLCLHDSADALLEAAKMANYAKFQKMCDLLFVMFAMVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFNLLLLLVQGLNCFWSYLIVKIAWKAVSKGKVSKDDRSDIESSSEDEDSEPPGKKPHTSTTTNGTSGTNGYLLTGPCSMDD", "length": 384, "header": "tr|G3GU80-1|A0A8C2N5K5_CRIGR Computationally mapped isoform of Ceramide synthase 6 isoform X1 OS=Cricetulus griseus OX=10029 GN=Cers6 PE=3 SV=1 CANONICAL=A0A8C2N5K5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3GU80", "url": "https://www.uniprot.org/uniprotkb/G3GU80" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3GU80", "url": "https://www.uniprot.org/uniprotkb/G3GU80" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761613", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761613", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A742-1", "protein_name": "Ceramide synthase 6", "gene_name": "Cers6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFIAKPCAVALNIQANGPQIAQPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTRFCESMWRFSFYLYVFSYGVRFLKQTPWLWNTRHCWYNYPYQPLTADLHYYYILELSFYWSLMVSQFTDIKRKDFGIMFLHHLATIFLITFSYVNNMARVGTLVLCLHDSADALLEAAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFNLLLLLLQGLNCFWSYLIVKIACKTVSKGKVSKDDRSDIESSSDDEDSEPPGKKLHSSTTTNGTSGTNGYLLTGPCSMDD", "length": 384 }, "evidence": [ { "id": "A0A8C2N5K5", "url": "https://omabrowser.org/oma/group/A0A8C2N5K5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1AA78-1", "protein_name": "Ceramide synthase 6", "gene_name": "CERS6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGILAWFWNERFWLPHNVTWADLQSTEEASFPQAEDLYLAFPLAFCIFMIRLLFERFIAKPCALGLKVQANGPQKAQPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTKFCESMWRFTFYLYIFTYGVRFLKKTPWLWNTRQCWNGYPYQPLMPDLHYYYIAELSFYWSLMFSQFIDIKRKDFGIMFTHHIVTVTLITFSYVTNLTRVGTLTLCLHDAADVVLEAAKMANYCKCQKLSDLLFLTFAIVFIVSRLGIYPLWILNTTLFELYEALGNFPALWVFNVLLVVLQILHYFWSYLIIKAAYKAISKGKVTKDDRSDIESSSDEEETVPRSKTLHSTITTNGTGGANGTNGYLTGSTCSEEH", "length": 387 }, "evidence": [ { "id": "A0A8C2N5K5", "url": "https://omabrowser.org/oma/group/A0A8C2N5K5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BP45-1", "protein_name": "sphingosine N-acyltransferase", "gene_name": "CERS6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCMLMVRLIFERFVAKPCAIALNIQANGPQIAQPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLKRFCESMWKFSYGLYIFTYGIRFLKKTPWLWNTKHCWYNYPYQPLTPDLHYYYILELSFYWSLMFSQFTDIKRKDFAVMFLHHLVAILLITFSYVNNMARVGTLILCLHDSADALLEAAKMANYAKFQKICDLLFVMFAMVFITTRLGVFPLWVLNTTLFESWEIVGPYPSWWVFNLLLLVIQGLNCFWSYLIVKIACKAISKGKVSKDDRSDIESSSDEEDSEPPGKNPHTATTTNGTSGTNGYLLTGACAMDD", "length": 384 }, "evidence": [ { "id": "A0A8C2N5K5", "url": "https://omabrowser.org/oma/group/A0A8C2N5K5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QPF3-1", "protein_name": "Ceramide synthase 6", "gene_name": "cers6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGILAWFWNERFWLPHNVTWADLKNTDDSTFPQAEDLYLACPLAFCMFMIRLVFERFIARPCALGLKIQANGPQKAQPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRTIQRWFRQRRNQEKPSTLARFCESMWRFSFYLYIFTYGVRFLKKSPWLWNTRECWYNYPYQPLTVDLHYYYILELSFYLSLLFSQFTDIRRKDFVLMFVHHVSTISLLSFSYVNNMARVGTLVLCLHDAADVLLEAAKMANYVKCQRLCPLLFVMFALVFMGSRLALYPVWILNTTVFESWEIIGPYPSWWLFNGLLVLLQALHTFWSYLIVRIACRAISRGKAGKWNPLHVSKDDRSDIESSSDEDELHPPLQKHHTNGTNGAHGTNGYLSSSLCPDEH", "length": 391 }, "evidence": [ { "id": "A0A8C2N5K5", "url": "https://omabrowser.org/oma/group/A0A8C2N5K5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZMG9-1", "protein_name": "Ceramide synthase 6", "gene_name": "CERS6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLHYYYILELSFYWSLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDSADALLEAAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFNLLLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSEPPGKNPHTATTTNGTSGTNGYLLTGSCSMDD", "length": 384 }, "evidence": [ { "id": "A0A8C2N5K5", "url": "https://omabrowser.org/oma/group/A0A8C2N5K5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C172-1", "protein_name": "Ceramide synthase 6", "gene_name": "Cers6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFIAKPCAIALNIQANGPQTAQPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTRFCESMWRFSFYLYVFSYGVRFLKQTPWLWNTRHCWYNYPYQPLTADLHYYYILELSFYWSLMVSQFTDIKRKDFGIMFLHHLATIFLITFSYVNNMARVGTLVLCLHDSADALLEAAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFNLLLLLLQGLNCFWSYLIVKIACKTVSKGKVSKDDRSDIESSSDDEDSEPPGKKPHSSTTTNGTSGTNGYLLTGPCSVDD", "length": 384 }, "evidence": [ { "id": "A0A8C2N5K5", "url": "https://omabrowser.org/oma/group/A0A8C2N5K5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5K5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5K5" } ], "pmid": "" }, { "name": "sphingosine N-acyltransferase activity", "id": "GO:0050291", "url": 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predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003621485.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035294399", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294399" } ] }, { "annotation": "Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.", "evidence": [ { "database": "UniProtKB", "id": "G3INY3", "url": "https://www.uniprot.org/uniprotkb/G3INY3#function" }, { "database": "UniProtKB", "id": "ARBA00024794", "url": "https://www.uniprot.org/uniprotkb/ARBA00024794#function" }, { "database": "UniProtKB", "id": "A0A9J7H476", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H476#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H476", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H476" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Csf3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H476", "locus": {} } ], "crossref": [ { "id": "100755744", "url": "https://www.ncbi.nlm.nih.gov/gene/100755744", "database": "GeneID", 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"Protein" ] }, { "id": "A0A9J7H476-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H476-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3INY3", "url": "https://www.uniprot.org/uniprotkb/G3INY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3INY3-1", "url": "https://www.uniprot.org/uniprotkb/G3INY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQPSAQSRRKLMAVHLLPALQLLLWHSALWTGQEAIPLVSVTSRPPPLPWPRSFLLKSLEQVRKIQTRNSELLEQLCATYKLCHPEELVLLGHSLGIPQAPLSRCSIQALQLTKCLSQLHSGLFLYQGLLQALTGISPELAPTVDMLQLDVANFATTIWQQMESLGVAPTVQPTQSTLPTFTSAFQRRAGGVLAASHLQSFLETAHCTLNHLV", "length": 214, "header": "tr|A0A9J7H476-1|A0A9J7H476_CRIGR Isoform 1 of Granulocyte colony-stimulating factor OS=Cricetulus griseus OX=10029 GN=Csf3 PE=3 SV=1 CANONICAL=A0A9J7H476-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H476-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H476/entry#A0A9J7H476-1", "sequence": { "sequence": "MAQPSAQSRRKLMAVHLLPALQLLLWHSALWTGQEAIPLVSVTSRPPPLPWPRSFLLKSLEQVRKIQTRNSELLEQLCATYKLCHPEELVLLGHSLGIPQAPLSRCSIQALQLTKCLSQLHSGLFLYQGLLQALTGISPELAPTVDMLQLDVANFATTIWQQMESLGVAPTVQPTQSTLPTFTSAFQRRAGGVLAASHLQSFLETAHCTLNHLV", "length": 214, "header": "tr|A0A9J7H476-1|A0A9J7H476_CRIGR Isoform 1 of Granulocyte colony-stimulating factor OS=Cricetulus griseus OX=10029 GN=Csf3 PE=3 SV=1 CANONICAL=A0A9J7H476-1" }, "locus": {} }, { "isoform_ac": "G3INY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H476/entry#G3INY3-1", "sequence": { "sequence": "MAQPSAQSRRKLMALQLLLWHSALWTGQEAIPLVSVTSRPPPLPWPRSFLLKSLEQVRKIQTRNSELLEQLCATYKLCHPEELVLLGHSLGIPQAPLSRCSIQALQLTKCLSQLHSGLFLYQGLLQALTGISPELAPTVDMLQLDVANFATTIWQQMESLGVAPTVQPTQSTLPTFTSAFQRRAGGVLAASHLQSFLETAHCTLNHLV", "length": 208, "header": "tr|G3INY3-1|A0A9J7H476_CRIGR Computationally mapped isoform of Granulocyte colony-stimulating factor OS=Cricetulus griseus OX=10029 GN=Csf3 PE=3 SV=1 CANONICAL=A0A9J7H476-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 171, "start_aa": "Thr", "end_pos": 171, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr171", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 175, "start_aa": "Thr", "end_pos": 175, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr175", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3INY3", "url": "https://www.uniprot.org/uniprotkb/G3INY3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3INY3", "url": "https://www.uniprot.org/uniprotkb/G3INY3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755744", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755744", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZZ00-1", "protein_name": "Colony stimulating factor 3", "gene_name": "CSF3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MCCLTREYRRPMGGTGGHVGLQPFRPPRISSVPSPCSFGTPSPGGSPEHRWGDPASGPCVTRCPAAVLALALVLGAPWQALHGAPLAELSGDHDFQLFLHKNLEFTRKIRGDVAALQRAVCDTFQLCTEEELQLVQPDPHLVQAPLDQCHKRGFQAEVCFTQIRAGLHAYHDSLGAVLRLLPNHTTLVETLQLDAANLSSNIQQQMEDLGLDTVTLPAEQRSPPPTFSGPFQQQVGGFFILANFQRFLETAYRALRHLTRL", "length": 261 }, "evidence": [ { "id": "A0A9J7H476", "url": "https://omabrowser.org/oma/group/A0A9J7H476/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F7FGY7-1", "protein_name": "Granulocyte colony-stimulating factor", "gene_name": "Csf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKGPLELGPGRAQSCSPDHPEFMAQLSAQGRMKLMALQLLLWHSALWSGQEAIPLLTVSSLPPSLPLPRSFLLKSLEQVRKIQARNTELLEQLCATYKLCHPEELVLFGHSLGIPKASLSSCSSQALQQTKCLSQLHSGLFLYQGLLQALAGISSELAPTLDMLHLDVDNFATTIWQQMESLGVAPTVQPTQSTMPIFTSAFQRRAGGVLVTSYLQSFLETAHHALHHLA", "length": 231 }, "evidence": [ { "id": "A0A9J7H476", "url": "https://omabrowser.org/oma/group/A0A9J7H476/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O02837-1", "protein_name": "Granulocyte colony-stimulating factor", "gene_name": "CSF3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"id": "A0A9J7GZU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZV7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H097", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H097-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H097-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H124", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H124", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H124-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H124-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1J1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1J1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1J1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H270", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H270", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H270-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H270-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2Q7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2R5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2R5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2R5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIQ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQF7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYP2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K622", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K622", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K622-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K622-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K7Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K7Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9E3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVCISASSRCLHFISPHANVEFSREGLRATLSQMAPVGPAQVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDTVHKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEVSMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSARDSEPRNPGASPAEPLCVENDSSSLEDASTN", "length": 692, "header": "tr|A0A9J7H2Q7-1|A0A9J7H2Q7_CRIGR Isoform 1 of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FZK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7FZK5-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDTVHKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEMRKMKLGLVK", "length": 587, "header": "tr|A0A9J7FZK5-1|A0A9J7H2Q7_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7FZU6-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDTVHKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSARDSEPRNPGASPAEPLCVENDSSSLEDASTN", "length": 643, "header": "tr|A0A9J7FZU6-1|A0A9J7H2Q7_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G012-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7G012-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDTVHKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEVSMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSARDSEPRNPGASPAEPLCVENDSSSLEDASTN", "length": 652, "header": "tr|A0A9J7G012-1|A0A9J7H2Q7_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G023-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7G023-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEVSMSVEWNGGVPSRASLCGKRQQQPRRR", "length": 597, "header": "tr|A0A9J7G023-1|A0A9J7H2Q7_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G4B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7G4B3-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEVSMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSARDSEPRNPGASPAEPLCVENDSSSLEDASTN", "length": 644, "header": "tr|A0A9J7G4B3-1|A0A9J7H2Q7_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GWZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7GWZ5-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVCISASSRCLHFISPHANVEFSREGLRATLSQMAPVGPAQVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEGVPSRASLCGKRQQQPRRR", "length": 628, "header": "tr|A0A9J7GWZ5-1|A0A9J7GWZ5_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GY62-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7GY62-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVCISASSRCLHFISPHANVEFSREGLRATLSQMAPVGPAQVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDTVHKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEGVPSRASLCGKRQQQPRRR", "length": 636, "header": "tr|A0A9J7GY62-1|A0A9J7GY62_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GYR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7GYR1-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVCISASSRCLHFISPHANVEFSREGLRATLSQMAPVGPAQVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDTVHKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEE", "length": 618, "header": "tr|A0A9J7GYR1-1|A0A9J7GYR1_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7GZU8-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVCISASSRCLHFISPHANVEFSREGLRATLSQMAPVGPAQVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEVSMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSARDSEPRNPGASPAEPLCVENDSSSLEDASTN", "length": 684, "header": "tr|A0A9J7GZU8-1|A0A9J7GZU8_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7GZV7-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEMRKMKLGLVK", "length": 579, "header": "tr|A0A9J7GZV7-1|A0A9J7GZV7_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H097-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7H097-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVCISASSRCLHFISPHANVEFSREGLRATLSQMAPVGPAQVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDTVHKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEVSMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSARDSEPRNPGNEIIVWQT", "length": 678, "header": "tr|A0A9J7H097-1|A0A9J7H097_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H124-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7H124-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVCISASSRCLHFISPHANVEFSREGLRATLSQMAPVGPAQVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEMRKMKLGLVK", "length": 619, "header": "tr|A0A9J7H124-1|A0A9J7H124_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7H1J1-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVCISASSRCLHFISPHANVEFSREGLRATLSQMAPVGPAQVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDTVHKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEMRKMKLGLVK", "length": 627, "header": "tr|A0A9J7H1J1-1|A0A9J7H1J1_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H270-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7H270-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVCISASSRCLHFISPHANVEFSREGLRATLSQMAPVGPAQVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDTVHKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEVSMSVEWNGE", "length": 627, "header": "tr|A0A9J7H270-1|A0A9J7H270_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7H2Q7-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVCISASSRCLHFISPHANVEFSREGLRATLSQMAPVGPAQVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDTVHKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEVSMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSARDSEPRNPGASPAEPLCVENDSSSLEDASTN", "length": 692, "header": "tr|A0A9J7H2Q7-1|A0A9J7H2Q7_CRIGR Isoform 1 of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7H2R5-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVCISASSRCLHFISPHANVEFSREGLRATLSQMAPVGPAQVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEE", "length": 610, "header": "tr|A0A9J7H2R5-1|A0A9J7H2R5_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JIQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7JIQ2-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDTVHKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEVSMSVEWNGMRKMKLGLVK", "length": 596, "header": "tr|A0A9J7JIQ2-1|A0A9J7H2Q7_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JNM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7JNM2-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSARDSEPRNPGASPAEPLCVENDSSSLEDASTN", "length": 635, "header": "tr|A0A9J7JNM2-1|A0A9J7H2Q7_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7JQF7-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEVSMSVEWNGMRKMKLGLVK", "length": 588, "header": "tr|A0A9J7JQF7-1|A0A9J7H2Q7_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JRK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7JRK4-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDTVHKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEGVPSRASLCGKRQQQPRRR", "length": 596, "header": "tr|A0A9J7JRK4-1|A0A9J7H2Q7_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JYP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7JYP2-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVCISASSRCLHFISPHANVEFSREGLRATLSQMAPVGPAQVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSARDSEPRNPGASPAEPLCVENDSSSLEDASTN", "length": 675, "header": "tr|A0A9J7JYP2-1|A0A9J7H2Q7_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K622-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7K622-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVCISASSRCLHFISPHANVEFSREGLRATLSQMAPVGPAQVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDTVHKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSARDSEPRNPGASPAEPLCVENDSSSLEDASTN", "length": 683, "header": "tr|A0A9J7K622-1|A0A9J7H2Q7_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K7Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7K7Z8-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVCISASSRCLHFISPHANVEFSREGLRATLSQMAPVGPAQVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDTVHKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEVSMSVEWNGMRKMKLGLVK", "length": 636, "header": "tr|A0A9J7K7Z8-1|A0A9J7H2Q7_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K9E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7/entry#A0A9J7K9E3-1", "sequence": { "sequence": "MLRARPRRRCLLLRRPGLCAAWARDSATSAALPTGRMYDSMSTMVYIQEEKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVCISASSRCLHFISPHANVEFSREGLRATLSQMAPVGPAQVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQRDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDTVHKQRVAEVLNDPENMEKRRSRESLHSDVVKYESGPDGGEEVSMSVEWNGGVPSRASLCGKRQQQPRRR", "length": 645, "header": "tr|A0A9J7K9E3-1|A0A9J7H2Q7_CRIGR Computationally mapped isoform of Kinesin light chain OS=Cricetulus griseus OX=10029 GN=Klc1 PE=3 SV=1 CANONICAL=A0A9J7H2Q7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZK5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZK5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100689219", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100689219", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2Q7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2Q7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2Q7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2Q7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2Q7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 681, "end_pos": 683 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H4G0-1", "uniprot_ac": "A0A9J7H4G0", "uniprot_id": "A0A9J7H4G0_CRIGR", "mass": { "chemical_mass": 59672.0, "monoisotopic_mass": 59672.0 }, "refseq": { "ac": "XP_035302628", "name": "N-chimaerin isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302628" }, "gene_names": [ { "name": "Chn1", "type": "recommended", "evidence": [ { "id": "A0A9J7H4G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0" } ] }, { "name": "Chn1", "type": "synonym", "evidence": [ { "id": "XP_035302628", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302628" } ] } ], "protein_names": [ { "name": "N-chimaerin", "type": "recommended", "evidence": [ { "id": "A0A9J7H4G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0/entry#names_and_taxonomy" } ] }, { "name": "A-chimaerin", "type": "synonym", "evidence": [ { "id": "A0A9J7H4G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0/entry#names_and_taxonomy" } ] }, { "name": "Alpha-chimerin", "type": "synonym", "evidence": [ { "id": "A0A9J7H4G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0/entry#names_and_taxonomy" } ] }, { "name": "N-chimaerin isoform X5", "type": "synonym", "evidence": [ { "id": "XP_035302628", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302628" } ] }, { "name": "N-chimerin", "type": "synonym", "evidence": [ { "id": "A0A9J7H4G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0/entry#names_and_taxonomy" } ] }, { "name": "Rho GTPase-activating protein 2", "type": "synonym", "evidence": [ { "id": "A0A9J7H4G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302628", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302628" } ] }, { "annotation": "GTPase-activating protein for p21-rac.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAT2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAT2#function" }, { "database": "UniProtKB", "id": "PIRNR038015", "url": "https://www.uniprot.org/uniprotkb/PIRNR038015#function" }, { "database": "UniProtKB", "id": "ARBA00059172", "url": "https://www.uniprot.org/uniprotkb/ARBA00059172#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Chn1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0", "locus": {} } ], "crossref": [ { "id": "A0A9J7H4G0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H4G0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04372", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04372", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10352", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10352", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20806", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20806", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20856", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20856", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755161", "url": "https://www.ncbi.nlm.nih.gov/gene/100755161", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020454", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020454", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755161", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755161", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H4G0", "url": "https://www.orthodb.org/?gene=A0A9J7H4G0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46075:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46075:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46075:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46075:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302628", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302628", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G3F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3F2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3F2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7S6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7S6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H412", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H412", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H412-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H412-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAT2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATGAGARRFAELRGPGAPLANARVTFLAAAPRGLGAHAPRAAAPPRCRLPAAAGARSAGRRGSTMALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREETDQLLSVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHIGYTTLIREPAYKQHMAVLKETHDEKEATGQDGVSEKRLTSLVRRATLKENEQIPKYEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHITKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALRLLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRSPELDPMAALNDIRYQRLVVELLIKNEDILF", "length": 525, "header": "tr|A0A9J7H4G0-1|A0A9J7H4G0_CRIGR Isoform 1 of N-chimaerin OS=Cricetulus griseus OX=10029 GN=Chn1 PE=4 SV=1 CANONICAL=A0A9J7H4G0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G3F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0/entry#A0A9J7G3F2-1", "sequence": { "sequence": "MTINPIYEHIGYTTLIREPAYKQHMAVLKETHDEKEATGQDGVSEKRLTSLVRRATLKENEQIPKYEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHITKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALRLLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRSPELDPMAALNDIRYQRLVVELLIKNEDILF", "length": 323, "header": "tr|A0A9J7G3F2-1|A0A9J7H4G0_CRIGR Computationally mapped isoform of N-chimaerin OS=Cricetulus griseus OX=10029 GN=Chn1 PE=4 SV=1 CANONICAL=A0A9J7H4G0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G7S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0/entry#A0A9J7G7S6-1", "sequence": { "sequence": "MTFLTSLVRRATLKENEQIPKYEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHITKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALRLLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRSPELDPMAALNDIRYQRLVVELLIKNEDILF", "length": 279, "header": "tr|A0A9J7G7S6-1|A0A9J7H4G0_CRIGR Computationally mapped isoform of N-chimaerin OS=Cricetulus griseus OX=10029 GN=Chn1 PE=4 SV=1 CANONICAL=A0A9J7H4G0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H412-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0/entry#A0A9J7H412-1", "sequence": { "sequence": "MAATGAGARRFAELRGPGAPLANARVTFLAAAPRGLGAHAPRAAAPPRCRLPAAAGARSAGRRGSTMALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREETDQLLSVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHIGYTTLIREPAYKQHMAVLKETHDEKEATGQDGVSEKRLTSLVRRATLKENEQIPKYEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHITKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAMLLGRGSTFRKINQTPERGCCLVWFSKRSSQYQYLP", "length": 469, "header": "tr|A0A9J7H412-1|A0A9J7H412_CRIGR Computationally mapped isoform of N-chimaerin OS=Cricetulus griseus OX=10029 GN=Chn1 PE=4 SV=1 CANONICAL=A0A9J7H4G0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H4G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0/entry#A0A9J7H4G0-1", "sequence": { "sequence": "MAATGAGARRFAELRGPGAPLANARVTFLAAAPRGLGAHAPRAAAPPRCRLPAAAGARSAGRRGSTMALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREETDQLLSVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHIGYTTLIREPAYKQHMAVLKETHDEKEATGQDGVSEKRLTSLVRRATLKENEQIPKYEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHITKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALRLLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRSPELDPMAALNDIRYQRLVVELLIKNEDILF", "length": 525, "header": "tr|A0A9J7H4G0-1|A0A9J7H4G0_CRIGR Isoform 1 of N-chimaerin OS=Cricetulus griseus OX=10029 GN=Chn1 PE=4 SV=1 CANONICAL=A0A9J7H4G0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0/entry#A0A9J7KAT2-1", "sequence": { "sequence": "MAATGAGARRFAELRGPGAPLANARVTFLAAAPRGLGAHAPRAAAPPRCRLPAAAGARSAGRRGSTMALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREETDQLLSVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHIGYTTLIREPAYKQHMAVLKETHDEKEATGQDGVSEKRVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHITKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALRLLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRSPELDPMAALNDIRYQRLVVELLIKNEDILF", "length": 499, "header": "tr|A0A9J7KAT2-1|A0A9J7H4G0_CRIGR Computationally mapped isoform of N-chimaerin OS=Cricetulus griseus OX=10029 GN=Chn1 PE=4 SV=1 CANONICAL=A0A9J7H4G0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3F2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3F2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755161", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755161", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0" } ], "pmid": "" }, { "name": "ephrin receptor binding", "id": "GO:0046875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046875", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0" } ], "pmid": "" }, { "name": "ephrin receptor signaling pathway", "id": "GO:0048013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048013", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0" } ], "pmid": "" }, { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H4G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0" }, { "id": "PS50081", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50081" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phorbol-ester/DAG-type", "eco_id": "ECO_0000259", "start_pos": 271, "end_pos": 321, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H4G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 334, "end_pos": 525, "start_aa": "Cys", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H4G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G0" }, { "id": "PS50001", "database": "PROSITE", "url": 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H3T4-1", "uniprot_ac": "A0A9J7H3T4", "uniprot_id": "A0A9J7H3T4_CRIGR", "mass": { "chemical_mass": 158436.0, "monoisotopic_mass": 158436.0 }, "refseq": { "ac": "XP_035302505", "name": "zinc finger protein 335 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302505" }, "gene_names": [ { "name": "Znf335", "type": "recommended", "evidence": [ { "id": "A0A9J7H3T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T4" } ] }, { "name": "Znf335", "type": "synonym", "evidence": [ { "id": "XP_035302505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302505" } ] } ], "protein_names": [ { "name": "Zinc finger protein 335 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7H3T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T4/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 335 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035302505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302505" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302505", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302505" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3T4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf335", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T4", "locus": {} } ], "crossref": [ { "id": "100770994", "url": "https://www.ncbi.nlm.nih.gov/gene/100770994", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050688", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050688", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770994", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770994", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QHMRERH", "url": "https://omabrowser.org/oma/group/QHMRERH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G872", "url": "https://www.orthodb.org/?gene=A0A9J7G872", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G8M3", "url": "https://www.orthodb.org/?gene=A0A9J7G8M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H3T4", "url": "https://www.orthodb.org/?gene=A0A9J7H3T4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13909", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13909", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302505", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302505", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G872", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G872", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G872-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G872-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8M3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0V7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0V7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H382", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H382", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H382-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H382-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3T4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEENEVESSSDAAPRPGQPEEPSESGLGVGTSEAVSADSSDAAAAPGLTEADDSGVGQSSDSGSRSVEEVSESISTDALPHGYLPDSSSVSRGTVAEVPGGPPALVHSSVLPDPSLLVSDCTASSSDLGAAIDKIIESTIGPDLIQRCITVTSAEEGGAETTQYLILQGPDDGAPMTSPMSTSTLVNSLSAIETVADGPTSTSTCLEPPEEPQGEHSSAAQPLPACGPDELELQSLEALMEVVVVQQFKCKMCQYRSSTKATLLRHMRERHFRPAATAAAAGKRGRLRKWGTSTHKTTEEEGPEDEEEEEDDIVDAGAIDDLEEDSDYNPAEDEPRGRQLRLQRPTPSTPRPRRRPGRPRKLPRLETADFYDGVAEPLVSSQSTQSSPELQDLEAPSSSGPGCLWGKMGRGPVESGVSQSDAENAAHSCKDEPDVPPRRRGRPSRRFLGKKYRKYYYKSPKPLLRPYLCRICGSRFLSLEDLRFHVNSHEAGDPQLFKCLQCSYRSRRWSSLKEHMFNHVGSKPYKCDECSYTSVYRKDVIRHAAVHSRDRKKRPDPTPKLSSFPCPVCGRVYPMQKRLTQHMKTHSTEKPHMCDKCGKSFKKRYTFKMHLLTHIQAVAHRRFKCEFCEFVCDDKKALLNHQLSHVSDKPFRCSFCPYRTFREDFLLSHVAVKHTGAKPFACEYCHFSTRHKKNLRLHVRCRHANSFEEWGRRHPEDPPSRRRPFFSVQQIEELKQQHTGAPGLPSSAPGPQVPQEPAPFQSPETPPLLCPDALSGATIIYQQGAEESTAMATQTALDLLLNMSSQRELGATALQVAVVKSEGMEAELTSTGRQPSPEDTTPQVVTLHVGEPGSSLAAESQLGPSDLQQIALPSGSFGGASYSVITAPPLEERTSAPGTSYRPPPSALSEEPPGEAAQTVVVSDSLKEAGTHYIMAADGTQLHHIELTADGSISFPSPDTLASGTKWPLLQCEGPPRNGPEVISPLKTHHVEGPQGSPTPPPATSNTVGLVVPTSPPSAAALSAKKFSCKVCSEAFAGRAEMESHKRAHAGPAAFKCPDCPFHARQWPEVRAHMAQHSSLRPHQCNQCSFASKNKKDLRRHMLTHTNEKPFSCHLCGQRFNRNGHLKFHIQRLHSSDGRKTGASTARAPAQTIILNSEEETLATLHTALQSSHGVLGPERLQQALSQEHIFVAQEQTVTNQEEAAYIQEITTADGQTVQHLVTNDNQVQYIIAQDGVQHLLPQEYVVVPDGHHIQLPTSRSRKARSHTSSMSKVPHSCRSPRSSMFLCPQASSLLPRLSLRLQHILLLQRWPMLPWPKPRACLALRRQCLNTSNSCNTRASSTTSLPSRMTEPQRPNADLGYRGQLSWRLGTFLSYLGPPDTGQSVSLDSKGARPVLLWGSHGPQPGHAGYLSLLAGFGREVYFCLDGPTGSSVSIKGPESSPCSSLCTWC", "length": 1451, "header": "tr|A0A9J7H3T4-1|A0A9J7H3T4_CRIGR Isoform 1 of Zinc finger protein 335 isoform X1 OS=Cricetulus griseus OX=10029 GN=Znf335 PE=4 SV=1 CANONICAL=A0A9J7H3T4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G872-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T4/entry#A0A9J7G872-1", "sequence": { "sequence": "MEENEVESSSDAAPRPGQPEEPSESGLGVGTSEAVSADSSDAAAAPGLTEADDSGVGQSSDSGSRSVEEVSESISTDALPHGYLPDSSSVSRGTVAEVPGGPPALVHSSVLPDPSLLVSDCTASSSDLGAAIDKIIESTIGPDLIQRCITVTSAEEGGAETTQYLILQGPDDGAPMTSPMSTSTLVNSLSAIETVADGPTSTSTCLEPPEEPQGEHSSAAQPLPACGPDELELQSLEALMEVVVVQQFKCKMCQYRSSTKATLLRHMRERHFRPAATAAAAGKRGRLRKWGTSTHKTTEEEGPEDEEEEEDDIVDAGAIDDLEEDSDYNPAEDEPRGRQLRLQRPTPSTPRPRRRPGRPRKLPRLETADFYDGVAEPLVSSQSTQSSPELQDLEAPSSSGPGCLWGKMGRGPVESGVSQSDAENAAHSCKDEPDVPPRRRGRPSRRFLGKKYRKYYYKSPKPLLRPYLCRICGSRFLSLEDLRFHVNSHEAGDPQLFKCLQCSYRSRRWSSLKEHMFNHVGSKPYKCDECSYTSVYRKDVIRHAAVHSRDRKKRPDPTPKLSSFPCPVCGRVYPMQKRLTQHMKTHSTEKPHMCDKCGKSFKKRYTFKMHLLTHIQAVAHRRFKCEFCEFVCDDKKALLNHQLSHVSDKPFRCSFCPYRTFREDFLLSHVAVKHTGAKPFACEYCHFSTRHKKNLRLHVRCRHANSFEEWGRRHPEDPPSRRRPFFSVQQIEELKQQHTGAPGLPSSAPGPQVPQEPAPFQSPETPPLLCPDALSGATIIYQQGAEESTAMATQTALDLLLNMSSQRELGATALQVAVVKSEGMEAELTSTGRQPSPEDTTPQVVTLHVGEPGSSLAAESQLGPSDLQQIALPSGSFGGASYSVITAPPLEERTSAPGTSYSEEPPGEAAQTVVVSDSLKEAGTHYIMAADGTQLHHIELTADGSISFPSPDTLASGTKWPLLQCEGPPRNGPEVISPLKTHHVEGPQGSPTPPPATSNTVGLVVPTSPPSAAALSAKKFSCKVCSEAFAGRAEMESHKRAHAGPAAFKCPDCPFHARQWPEVRAHMAQHSSLRPHQCNQCSFASKNKKDLRRHMLTHTNEKPFSCHLCGQRFNRNGHLKFHIQRLHSSDGRKTGASTARAPAQTIILNSEEETLATLHTALQSSHGVLGPERLQQALSQEHIFVAQEQTVTNQEEAAYIQEITTADGQTVQHLVTNDNQVQYIIAQDGVQHLLPQEYVVVPDGHHIQVQEGQITHIQYEQGTPFLQESQIQYVPVSPGQQLVTQAQLEAAAHSAVTAVADAAMAQAQGLFGTEEAVPEHIQQLQHQGIEYDVITITDD", "length": 1339, "header": "tr|A0A9J7G872-1|A0A9J7H3T4_CRIGR Computationally mapped isoform of Zinc finger protein 335 isoform X1 OS=Cricetulus griseus OX=10029 GN=Znf335 PE=4 SV=1 CANONICAL=A0A9J7H3T4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G8M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T4/entry#A0A9J7G8M3-1", "sequence": { "sequence": "MEENEVESSSDAAPRPGQPEEPSESGLGVGTSEAVSADSSDAAAAPGLTEADDSGVGQSSDSGSRSVEEVSESISTDALPHGYLPDSSSVSRGTVAEVPGGPPALVHSSVLPDPSLLVSDCTASSSDLGAAIDKIIESTIGPDLIQRCITVTSAEEGGAETTQYLILQGPDDGAPMTSPMSTSTLVNSLSAIETVADGPTSTSTCLEPPEEPQGEHSSAAQPLPACGPDELELQSLEALMEVVVVQQFKCKMCQYRSSTKATLLRHMRERHFRPAATAAAAGKRGRLRKWGTSTHKTTEEEGPEDEEEEEDDIVDAGAIDDLEEDSDYNPAEDEPRGRQLRLQRPTPSTPRPRRRPGRPRKLPRLETADFYDGVAEPLVSSQSTQSSPELQDLEAPSSSGPGCLWGKMGRGPVESGVSQSDAENAAHSCKDEPDVPPRRRGRPSRRFLGKKYRKYYYKSPKPLLRPYLCRICGSRFLSLEDLRFHVNSHEAGDPQLFKCLQCSYRSRRWSSLKEHMFNHVGSKPYKCDECSYTSVYRKDVIRHAAVHSRDRKKRPDPTPKLSSFPCPVCGRVYPMQKRLTQHMKTHSTEKPHMCDKCGKSFKKRYTFKMHLLTHIQAVAHRRFKCEFCEFVCDDKKALLNHQLSHVSDKPFRCSFCPYRTFREDFLLSHVAVKHTGAKPFACEYCHFSTRHKKNLRLHVRCRHANSFEEWGRRHPEDPPSRRRPFFSVQQIEELKQQHTGAPGLPSSAPGPQVPQEPAPFQSPETPPLLCPDALSGATIIYQQGAEESTAMATQTALDLLLNMSSQRELGATALQVAVVKSEGMEAELTSTGRQPSPEDTTPQVVTLHVGEPGSSLAAESQLGPSDLQQIALPSGSFGGASYSVITAPPLEERTSAPGTSYRPPPSALSEEPPGEAAQTVVVSDSLKEAGTHYIMAADGTQLHHIELTADGSISFPSPDTLASGTKWPLLQCEGPPRNGPEVISPLKTHHVEGPQGSPTPPPATSNTVGLVVPTSPPSAAALSAKKFSCKVCSEAFAGRAEMESHKRAHAGPAAFKCPDCPFHARQWPEVRAHMAQHSSLRPHQCNQCSFASKNKKDLRRHMLTHTNEKPFSCHLCGQRFNRNGHLKFHIQRLHSSDGRKTGASTARAPAQTIILNSEEETLATLHTALQSSHGVLGPERLQQALSQEHIFVAQEQTVTNQEEAAYIQEITTADGQTVQHLVTNDNQVQYIIAQDGVQHLLPQEYVVVPDGHHIQVQEGQITHIQYEQGTPFLQESQIQYVPVSPGQQLVTQAQLEAAAHSAVTAVADAAMAQAQGLFGTEEAVPEHIQQLQHQGIEYDVITITDD", "length": 1346, "header": "tr|A0A9J7G8M3-1|A0A9J7H3T4_CRIGR Computationally mapped isoform of Zinc finger protein 335 isoform X1 OS=Cricetulus griseus OX=10029 GN=Znf335 PE=4 SV=1 CANONICAL=A0A9J7H3T4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H0V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T4/entry#A0A9J7H0V7-1", "sequence": { "sequence": "MEENEVESSSDAAPRPGQPEEPSESGLGVGTSEAVSADSSDAAAAPGLTEADDSGVGQSSDSGSRSVEEVSESISTDALPHGYLPDSSSVSRGTVAEVPGGPPALVHSSVLPDPSLLVSDCTASSSDLGAAIDKIIESTIGPDLIQRCITVTSAEEGGAETTQYLILQGPDDGAPMTSPMSTSTLVNSLSAIETVADGPTSTSTCLEPPEEPQGEHSSAAQPLPACGPDELELQSLEALMEVVVVQQFKCKMCQYRSSTKATLLRHMRERHFRPAATAAAAGKRGRLRKWGTSTHKTTEEEGPEDEEEEEDDIVDAGAIDDLEEDSDYNPAEDEPRGRQLRLQRPTPSTPRPRRRPGRPRKLPRLETADFYDGVAEPLVSSQSTQSSPELQDLEAPSSSGPGCLWGKMGRGPVESGVSQSDAENAAHSCKDEPDVPPRRRGRPSRRFLGKKYRKYYYKSPKPLLRPYLCRICGSRFLSLEDLRFHVNSHEAGDPQLFKCLQCSYRSRRWSSLKEHMFNHVGSKPYKCDECSYTSVYRKDVIRHAAVHSRDRKKRPDPTPKLSSFPCPVCGRVYPMQKRLTQHMKTHSTEKPHMCDKCGKSFKKRYTFKMHLLTHIQAVAHRRFKCEFCEFVCDDKKALLNHQLSHVSDKPFRCSFCPYRTFREDFLLSHVAVKHTGAKPFACEYCHFSTRHKKNLRLHVRCRHANSFEEWGRRHPEDPPSRRRPFFSVQQIEELKQQHTGAPGLPSSAPGPQVPQEPAPFQSPETPPLLCPDALSGATIIYQQGAEESTAMATQTALDLLLNMSSQRELGATALQVAVVKSEGMEAELTSTGRQPSPEDTTPQVVTLHVGEPGSSLAAESQLGPSDLQQIALPSGSFGGASYSVITAPPLEERTSAPGTSYSEEPPGEAAQTVVVSDSLKEAGTHYIMAADGTQLHHIELTADGSISFPSPDTLASGTKWPLLQCEGPPRNGPEVISPLKTHHVEGPQGSPTPPPATSNTVGLVVPTSPPSAAALSAKKFSCKVCSEAFAGRAEMESHKRAHAGPAAFKCPDCPFHARQWPEVRAHMAQHSSLRPHQCNQCSFASKNKKDLRRHMLTHTNEKPFSCHLCGQRFNRNGHLKFHIQRLHSSDGRKTGASTARAPAQTIILNSEEETLATLHTALQSSHGVLGPERLQQALSQEHIFVAQEQTVTNQEEAAYIQEITTADGQTVQHLVTNDNQVQYIIAQDGVQHLLPQEYVVVPDGHHIQLPTSRSRKARSHTSSMSKVPHSCRSPRSSMFLCPQASSLLPRLSLRLQHILLLQRWPMLPWPKPRACLALRRQCLNTSNSCNTRASSTTSLPSRMTEPQRPNADLGYRGQLSWRLGTFLSYLGPPDTGQSVSLDSKGARPVLLWGSHGPQPGHAGYLSLLAGFGREVYFCLDGPTGSSVSIKGPESSPCSSLCTWC", "length": 1444, "header": "tr|A0A9J7H0V7-1|A0A9J7H0V7_CRIGR Computationally mapped isoform of Zinc finger protein 335 isoform X3 OS=Cricetulus griseus OX=10029 GN=Znf335 PE=4 SV=1 CANONICAL=A0A9J7H3T4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H382-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T4/entry#A0A9J7H382-1", "sequence": { "sequence": "MEENEVESSSDAAPRPGQPEEPSESGLGVGTSEAVSADSSDAAAAPGLTEADDSGVGQSSDSGSRSVEEVSESISTDALPHGYLPDSSSVSRGTVAEVPGGPPALVHSSVLPDPSLLVSDCTASSSDLGAAIDKIIESTIGPDLIQRCITVTSAEEGGAETTQYLILQGPDDGAPMTSPMSTSTLVNSLSAIETVADGPTSTSTCLEPPEEPQGEHSSAAQPLPACGPDELELQSLEALMEVVVVQQFKCKMCQYRSSTKATLLRHMRERHFRPATAAAAGKRGRLRKWGTSTHKTTEEEGPEDEEEEEDDIVDAGAIDDLEEDSDYNPAEDEPRGRQLRLQRPTPSTPRPRRRPGRPRKLPRLETADFYDGVAEPLVSSQSTQSSPELQDLEAPSSSGPGCLWGKMGRGPVESGVSQSDAENAAHSCKDEPDVPPRRRGRPSRRFLGKKYRKYYYKSPKPLLRPYLCRICGSRFLSLEDLRFHVNSHEAGDPQLFKCLQCSYRSRRWSSLKEHMFNHVGSKPYKCDECSYTSVYRKDVIRHAAVHSRDRKKRPDPTPKLSSFPCPVCGRVYPMQKRLTQHMKTHSTEKPHMCDKCGKSFKKRYTFKMHLLTHIQAVAHRRFKCEFCEFVCDDKKALLNHQLSHVSDKPFRCSFCPYRTFREDFLLSHVAVKHTGAKPFACEYCHFSTRHKKNLRLHVRCRHANSFEEWGRRHPEDPPSRRRPFFSVQQIEELKQQHTGAPGLPSSAPGPQVPQEPAPFQSPETPPLLCPDALSGATIIYQQGAEESTAMATQTALDLLLNMSSQRELGATALQVAVVKSEGMEAELTSTGRQPSPEDTTPQVVTLHVGEPGSSLAAESQLGPSDLQQIALPSGSFGGASYSVITAPPLEERTSAPGTSYRPPPSALSEEPPGEAAQTVVVSDSLKEAGTHYIMAADGTQLHHIELTADGSISFPSPDTLASGTKWPLLQCEGPPRNGPEVISPLKTHHVEGPQGSPTPPPATSNTVGLVVPTSPPSAAALSAKKFSCKVCSEAFAGRAEMESHKRAHAGPAAFKCPDCPFHARQWPEVRAHMAQHSSLRPHQCNQCSFASKNKKDLRRHMLTHTNEKPFSCHLCGQRFNRNGHLKFHIQRLHSSDGRKTGASTARAPAQTIILNSEEETLATLHTALQSSHGVLGPERLQQALSQEHIFVAQEQTVTNQEEAAYIQEITTADGQTVQHLVTNDNQVQYIIAQDGVQHLLPQEYVVVPDGHHIQLPTSRSRKARSHTSSMSKVPHSCRSPRSSMFLCPQASSLLPRLSLRLQHILLLQRWPMLPWPKPRACLALRRQCLNTSNSCNTRASSTTSLPSRMTEPQRPNADLGYRGQLSWRLGTFLSYLGPPDTGQSVSLDSKGARPVLLWGSHGPQPGHAGYLSLLAGFGREVYFCLDGPTGSSVSIKGPESSPCSSLCTWC", "length": 1450, "header": "tr|A0A9J7H382-1|A0A9J7H382_CRIGR Computationally mapped isoform of Zinc finger protein 335 isoform X2 OS=Cricetulus griseus OX=10029 GN=Znf335 PE=4 SV=1 CANONICAL=A0A9J7H3T4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H3T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T4/entry#A0A9J7H3T4-1", "sequence": { "sequence": "MEENEVESSSDAAPRPGQPEEPSESGLGVGTSEAVSADSSDAAAAPGLTEADDSGVGQSSDSGSRSVEEVSESISTDALPHGYLPDSSSVSRGTVAEVPGGPPALVHSSVLPDPSLLVSDCTASSSDLGAAIDKIIESTIGPDLIQRCITVTSAEEGGAETTQYLILQGPDDGAPMTSPMSTSTLVNSLSAIETVADGPTSTSTCLEPPEEPQGEHSSAAQPLPACGPDELELQSLEALMEVVVVQQFKCKMCQYRSSTKATLLRHMRERHFRPAATAAAAGKRGRLRKWGTSTHKTTEEEGPEDEEEEEDDIVDAGAIDDLEEDSDYNPAEDEPRGRQLRLQRPTPSTPRPRRRPGRPRKLPRLETADFYDGVAEPLVSSQSTQSSPELQDLEAPSSSGPGCLWGKMGRGPVESGVSQSDAENAAHSCKDEPDVPPRRRGRPSRRFLGKKYRKYYYKSPKPLLRPYLCRICGSRFLSLEDLRFHVNSHEAGDPQLFKCLQCSYRSRRWSSLKEHMFNHVGSKPYKCDECSYTSVYRKDVIRHAAVHSRDRKKRPDPTPKLSSFPCPVCGRVYPMQKRLTQHMKTHSTEKPHMCDKCGKSFKKRYTFKMHLLTHIQAVAHRRFKCEFCEFVCDDKKALLNHQLSHVSDKPFRCSFCPYRTFREDFLLSHVAVKHTGAKPFACEYCHFSTRHKKNLRLHVRCRHANSFEEWGRRHPEDPPSRRRPFFSVQQIEELKQQHTGAPGLPSSAPGPQVPQEPAPFQSPETPPLLCPDALSGATIIYQQGAEESTAMATQTALDLLLNMSSQRELGATALQVAVVKSEGMEAELTSTGRQPSPEDTTPQVVTLHVGEPGSSLAAESQLGPSDLQQIALPSGSFGGASYSVITAPPLEERTSAPGTSYRPPPSALSEEPPGEAAQTVVVSDSLKEAGTHYIMAADGTQLHHIELTADGSISFPSPDTLASGTKWPLLQCEGPPRNGPEVISPLKTHHVEGPQGSPTPPPATSNTVGLVVPTSPPSAAALSAKKFSCKVCSEAFAGRAEMESHKRAHAGPAAFKCPDCPFHARQWPEVRAHMAQHSSLRPHQCNQCSFASKNKKDLRRHMLTHTNEKPFSCHLCGQRFNRNGHLKFHIQRLHSSDGRKTGASTARAPAQTIILNSEEETLATLHTALQSSHGVLGPERLQQALSQEHIFVAQEQTVTNQEEAAYIQEITTADGQTVQHLVTNDNQVQYIIAQDGVQHLLPQEYVVVPDGHHIQLPTSRSRKARSHTSSMSKVPHSCRSPRSSMFLCPQASSLLPRLSLRLQHILLLQRWPMLPWPKPRACLALRRQCLNTSNSCNTRASSTTSLPSRMTEPQRPNADLGYRGQLSWRLGTFLSYLGPPDTGQSVSLDSKGARPVLLWGSHGPQPGHAGYLSLLAGFGREVYFCLDGPTGSSVSIKGPESSPCSSLCTWC", "length": 1451, "header": "tr|A0A9J7H3T4-1|A0A9J7H3T4_CRIGR Isoform 1 of Zinc finger protein 335 isoform X1 OS=Cricetulus griseus OX=10029 GN=Znf335 PE=4 SV=1 CANONICAL=A0A9J7H3T4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 200, "start_aa": "Thr", "end_pos": 200, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr200", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 558, "start_aa": "Thr", "end_pos": 558, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr558", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 999, "start_aa": "Thr", "end_pos": 999, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr999", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G872", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G872" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G872", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G872" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770994", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770994", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2A5K6-1", "protein_name": "Zinc finger protein 335", "gene_name": "Znf335", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 1337 }, "evidence": [ { "id": "A0A9J7H3T4", "url": "https://omabrowser.org/oma/group/A0A9J7H3T4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1BPQ2-1", "protein_name": "Zinc finger protein 335", "gene_name": "ZNF335", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"length": 1346 }, "evidence": [ { "id": "A0A9J7H3T4", "url": "https://omabrowser.org/oma/group/A0A9J7H3T4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3V893-1", "protein_name": "Zinc finger protein 335", "gene_name": "Znf335", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"length": 1336 }, "evidence": [ { "id": "A0A9J7H3T4", "url": "https://omabrowser.org/oma/group/A0A9J7H3T4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H4Z2-1", "protein_name": "Zinc finger protein 335", "gene_name": "ZNF335", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"UniProtKB", "id": "A0A9J7H3T4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3T4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T4" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3T4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T4" } ], "pmid": "" }, { "name": "positive regulation of neurogenesis", "id": "GO:0050769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050769", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3T4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1331, "end_pos": 1333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 802, "end_pos": 804, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H3T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 248, "end_pos": 276, "start_aa": "Phe", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { 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"glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H336-1", "uniprot_ac": "A0A9J7H336", "uniprot_id": "A0A9J7H336_CRIGR", "mass": { "chemical_mass": 74229.0, "monoisotopic_mass": 74229.0 }, "refseq": { "ac": "XP_035303245", "name": "dystrobrevin beta isoform X10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303245" }, "gene_names": [ { "name": "Dtnb", "type": "recommended", "evidence": [ { "id": "A0A9J7H336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336" } ] }, { "name": "Dtnb", "type": "synonym", "evidence": [ { "id": "XP_035303245", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303245" } ] } ], "protein_names": [ { "name": "Dystrobrevin", "type": "recommended", "evidence": [ { "id": "A0A9J7H336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336/entry#names_and_taxonomy" } ] }, { "name": "dystrobrevin beta isoform X10", "type": "synonym", "evidence": [ { "id": "XP_035303245", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303245" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303245", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303245" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H336", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dtnb", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336", "locus": {} } ], "crossref": [ { "id": "A0A9J7H336", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H336", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02334", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02334", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16244", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16244", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756605", "url": "https://www.ncbi.nlm.nih.gov/gene/100756605", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017432", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017432", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756605", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756605", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H336", "url": "https://www.orthodb.org/?gene=A0A9J7H336", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JVN1", "url": "https://www.orthodb.org/?gene=A0A9J7JVN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12268", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12268", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12268:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12268:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09068", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09068", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303245", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303245", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G958", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G958", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G958-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G958-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9P6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9P6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GA79", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GA79-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDS0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H336", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H336-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JVN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JVN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JX86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JX86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JX86-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JX86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K7R4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K7R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7R4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIIVHLLMMIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSSGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGTHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHIVPPRPLNMNDTVVSHMSSGVPTPTKRLQYSQDTPSLLADEHALIASYVARLQHCTRVLDSPSRLDEEHRLIARYAARLAAEAGNMTRPPTDASFNFDANRQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGVGGDVQEAFAQGTRRNLRNDLLVAADSITNTMSSLVKELHSGETQSSPPVSASPLCPSVPALSCHQAHGASFQSILPSRNTQELHPVPPSHM", "length": 659, "header": "tr|A0A9J7H336-1|A0A9J7H336_CRIGR Isoform 1 of Dystrobrevin OS=Cricetulus griseus OX=10029 GN=Dtnb PE=3 SV=1 CANONICAL=A0A9J7H336-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G958-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336/entry#A0A9J7G958-1", "sequence": { "sequence": "MIIVHLLMMIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSSGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGTHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHIVPPRPLNMNDTVVSHMSSGVPTPTKRLQYSQDTPSLLADEHALIASYVARLQHCTRVLDSPSRLDEEHRLIARYAARLAAEAGNMTRPPTDASFNFDANRQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEEEQKQAAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGVGGDVQEAFAQGTRRNLRNDLLVAADSITNTMSSLVKELHSG", "length": 616, "header": "tr|A0A9J7G958-1|A0A9J7H336_CRIGR Computationally mapped isoform of Dystrobrevin OS=Cricetulus griseus OX=10029 GN=Dtnb PE=3 SV=1 CANONICAL=A0A9J7H336-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336/entry#A0A9J7G9P6-1", "sequence": { "sequence": "MIIVHLLMMIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSSGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGTHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHIVPPRPLNMNDTVVSHMSSGVPTPTKRLQYSQDTPSLLADEHALIASYVARLQHCTRVLDSPSRLDEEHRLIARYAARLAAEAGNMTRPPTDASFNFDANRQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGVGGDVQEAFAQGTRRNLRNDLLVAADSITNTMSSLVKELHSAKEGTEEEEEMQDEKDRGEGKSALLV", "length": 634, "header": "tr|A0A9J7G9P6-1|A0A9J7H336_CRIGR Computationally mapped isoform of Dystrobrevin OS=Cricetulus griseus OX=10029 GN=Dtnb PE=3 SV=1 CANONICAL=A0A9J7H336-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GA79-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336/entry#A0A9J7GA79-1", "sequence": { "sequence": "MIIVHLLMMIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSSGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGTHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHIVPPRPLNMNDTVVSHMSSGVPTPTKRLQYSQDTPSLLADEHALIASYVARLQHCTRVLDSPSRLDEEHRLIARYAARLAAEAGNMTRPPTDASFNFDANRQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEEEQKQAAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGVGGDVQEAFAQGTRRNLRNDLLVAADSITNTMSSLVKELHSAKEGTEEEEEMQDEKDRGEGKSALLV", "length": 641, "header": "tr|A0A9J7GA79-1|A0A9J7H336_CRIGR Computationally mapped isoform of Dystrobrevin OS=Cricetulus griseus OX=10029 GN=Dtnb PE=3 SV=1 CANONICAL=A0A9J7H336-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GDS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336/entry#A0A9J7GDS0-1", "sequence": { "sequence": "MIIVHLLMMIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSSGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGTHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHIVPPRPLNMNDTVVSHMSSGVPTPTKSVLDSPSRLDEEHRLIARYAARLAAEAGNMTRPPTDASFNFDANRQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEEEQKQAAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGVGGDVQEAFAQGTRRNLRNDLLVAADSITNTMSSLVKELHSAKEGTEEEEEMQDEKDRGEGKSALLV", "length": 611, "header": "tr|A0A9J7GDS0-1|A0A9J7H336_CRIGR Computationally mapped isoform of Dystrobrevin OS=Cricetulus griseus OX=10029 GN=Dtnb PE=3 SV=1 CANONICAL=A0A9J7H336-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H336-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336/entry#A0A9J7H336-1", "sequence": { "sequence": "MIIVHLLMMIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSSGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGTHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHIVPPRPLNMNDTVVSHMSSGVPTPTKRLQYSQDTPSLLADEHALIASYVARLQHCTRVLDSPSRLDEEHRLIARYAARLAAEAGNMTRPPTDASFNFDANRQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGVGGDVQEAFAQGTRRNLRNDLLVAADSITNTMSSLVKELHSGETQSSPPVSASPLCPSVPALSCHQAHGASFQSILPSRNTQELHPVPPSHM", "length": 659, "header": "tr|A0A9J7H336-1|A0A9J7H336_CRIGR Isoform 1 of Dystrobrevin OS=Cricetulus griseus OX=10029 GN=Dtnb PE=3 SV=1 CANONICAL=A0A9J7H336-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H3S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336/entry#A0A9J7H3S3-1", "sequence": { "sequence": "MIIVHLLMMIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSSGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGTHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHIVSSVHMKWIFVVKGPAPHFGSHNSLSDLVFKEPASLSAAITVEHVLL", "length": 388, "header": "tr|A0A9J7H3S3-1|A0A9J7H3S3_CRIGR Computationally mapped isoform of Dystrobrevin beta isoform X15 OS=Cricetulus griseus OX=10029 GN=Dtnb PE=3 SV=1 CANONICAL=A0A9J7H336-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JVN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336/entry#A0A9J7JVN1-1", "sequence": { "sequence": "MIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSSGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGTHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHIVPPRPLNMNDTVVSHMSSGVPTPTKRLQYSQDTPSLLADEHALIASYVARLQHCTRVLDSPSRLDEEHRLIARYAARLAAEAGNMTRPPTDASFNFDANRQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGVGGDVQEAFAQGTRRNLRNDLLVAADSITNTMSSLVKELHSGETQSSPPVSASPLCPSVPALSCHQAHGASFQSILPSRNTQELHPVPPSHM", "length": 651, "header": "tr|A0A9J7JVN1-1|A0A9J7H336_CRIGR Computationally mapped isoform of Dystrobrevin OS=Cricetulus griseus OX=10029 GN=Dtnb PE=3 SV=1 CANONICAL=A0A9J7H336-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JX86-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336/entry#A0A9J7JX86-1", "sequence": { "sequence": "MIIVHLLMMIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSSGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGTHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHIVPPRPLNMNDTVVSHMSSGVPTPTKSVLDSPSRLDEEHRLIARYAARLAAEAGNMTRPPTDASFNFDANRQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHGPQDSLSGVGGDVQEAFAQGTRRNLRNDLLVAADSITNTMSSLVKELHSAKEGTEEEEEMQDEKDRGEGKSALLV", "length": 604, "header": "tr|A0A9J7JX86-1|A0A9J7H336_CRIGR Computationally mapped isoform of Dystrobrevin OS=Cricetulus griseus OX=10029 GN=Dtnb PE=3 SV=1 CANONICAL=A0A9J7H336-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K7R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336/entry#A0A9J7K7R4-1", "sequence": { "sequence": "MIIVHLLMMIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSSGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGTHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHIVPPRPLNMNDTVVSHMSSGVPTPTKREKETGVAHRTTYSVMNSNSIFCLIKPGVSASRSDC", "length": 402, "header": "tr|A0A9J7K7R4-1|A0A9J7H336_CRIGR Computationally mapped isoform of Dystrobrevin OS=Cricetulus griseus OX=10029 GN=Dtnb PE=3 SV=1 CANONICAL=A0A9J7H336-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 475, "start_aa": "Thr", "end_pos": 475, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr475", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G958", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G958" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G958", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G958" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756605", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756605", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H336", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H336", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H336", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H336", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "synaptic signaling", "id": "GO:0099536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099536", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H336", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H336" }, { "id": "PS50135", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50135" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZZ-type", "eco_id": "ECO_0000259", "start_pos": 246, "end_pos": 302, "start_aa": "Phe", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 475 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 350, "end_pos": 352 }, { "start_pos": 425, "end_pos": 427 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QBZ8-1", "uniprot_ac": "A0A8C2QBZ8", "uniprot_id": "A0A8C2QBZ8_CRIGR", "mass": { "chemical_mass": 45625.0, "monoisotopic_mass": 45625.0 }, "refseq": { "ac": "XP_003510943", "name": "protein fuzzy homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510943" }, "gene_names": [ { "name": "Fuz", "type": "recommended", "evidence": [ { "id": "A0A8C2QBZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8" } ] }, { "name": "Fuz", "type": "synonym", "evidence": [ { "id": "XP_003510943", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510943" } ] } ], "protein_names": [ { "name": "Protein fuzzy homolog isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2QBZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8/entry#names_and_taxonomy" } ] }, { "name": "protein fuzzy homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003510943", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510943" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614984.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510943", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510943" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fuz", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8", "locus": {} } ], "crossref": [ { "id": "cd21091", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21091", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772773", "url": "https://www.ncbi.nlm.nih.gov/gene/100772773", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026069", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026069", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772773", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772773", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LDQYSCS", "url": "https://omabrowser.org/oma/group/LDQYSCS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LAJ0", "url": "https://www.orthodb.org/?gene=A0A8C2LAJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QBZ8", "url": "https://www.orthodb.org/?gene=A0A8C2QBZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13559", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13559", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13559:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13559:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF19036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510943", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510943", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LAJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LAJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QBZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QBZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDEGAGSTVHLLCLAASSGVPLFCRSSCGGAPSRQQLPFSVIGSLNGVHMFGQNLDVQLNSARTEDTTVVWKSFHDSITLIALSSEEGTSELRLERMLHMVFGAMVLIVGLEELTNIRNVERLKKELRASYCLIDSFLGNSELIGDLTQCVDCVIPPEGSFMQETLSGFAEATGTAFVSLLVSGRVVAATEGWWRLGMPEAVLLPWLVGSLPPQAARDYPVYLPHGSPTVPHRLLTLTLLRGLELCLLCGPRPPLSQLDPQLLERWWQPLLEPLRACLPLGPRVLPEGFPLHSDILGLLLLHLDLRRCLFTVEPSRNKEPSPEQRRRLLRNFYTLVATTHFSPEPGPTEKEEDEAHPAQSPRACYLVLGPGEGWRLVALQLGLRLLLLMLSPQSPTHGLRSLATHTLQALTPFL", "length": 415, "header": "tr|A0A8C2QBZ8-1|A0A8C2QBZ8_CRIGR Isoform 1 of Protein fuzzy homolog isoform X1 OS=Cricetulus griseus OX=10029 GN=Fuz PE=3 SV=1 CANONICAL=A0A8C2QBZ8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LAJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8/entry#A0A8C2LAJ0-1", "sequence": { "sequence": "MGDEGAGSTVHLLCLAASSGVPLFCRSSCGGAPSRQQLPFSVIGSLNGVHMFGQNLDVQLNSARTEDTTVVWKSFHDSITLIALSSEEGTSELRLERMLHMVFGAMVLIVGLEELTNIRNVERLKKELRASYCLIDSFLGNSELIGDLTQCVDCVIPPEGSFMQVPHRLLTLTLLRGLELCLLCGPRPPLSQLDPQLLERWWQPLLEPLRACLPLGPRVLPEGFPLHSDILGLLLLHLDLRRCLFTVEPSRNKEPSPEQRRRLLRNFYTLVATTHFSPEPGPTEKEEDEAHPAQSPRACYLVLGPGEGWRLVALQLGLRLLLLMLSPQSPTHGLRSLATHTLQALTPFL", "length": 349, "header": "tr|A0A8C2LAJ0-1|A0A8C2QBZ8_CRIGR Computationally mapped isoform of Protein fuzzy homolog isoform X1 OS=Cricetulus griseus OX=10029 GN=Fuz PE=3 SV=1 CANONICAL=A0A8C2QBZ8-1" }, "locus": {} }, { "isoform_ac": "A0A8C2QBZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8/entry#A0A8C2QBZ8-1", "sequence": { "sequence": "MGDEGAGSTVHLLCLAASSGVPLFCRSSCGGAPSRQQLPFSVIGSLNGVHMFGQNLDVQLNSARTEDTTVVWKSFHDSITLIALSSEEGTSELRLERMLHMVFGAMVLIVGLEELTNIRNVERLKKELRASYCLIDSFLGNSELIGDLTQCVDCVIPPEGSFMQETLSGFAEATGTAFVSLLVSGRVVAATEGWWRLGMPEAVLLPWLVGSLPPQAARDYPVYLPHGSPTVPHRLLTLTLLRGLELCLLCGPRPPLSQLDPQLLERWWQPLLEPLRACLPLGPRVLPEGFPLHSDILGLLLLHLDLRRCLFTVEPSRNKEPSPEQRRRLLRNFYTLVATTHFSPEPGPTEKEEDEAHPAQSPRACYLVLGPGEGWRLVALQLGLRLLLLMLSPQSPTHGLRSLATHTLQALTPFL", "length": 415, "header": "tr|A0A8C2QBZ8-1|A0A8C2QBZ8_CRIGR Isoform 1 of Protein fuzzy homolog isoform X1 OS=Cricetulus griseus OX=10029 GN=Fuz PE=3 SV=1 CANONICAL=A0A8C2QBZ8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAJ0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAJ0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772773", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772773", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BBF8-1", "protein_name": "Fuzzy planar cell polarity protein", "gene_name": "FUZ", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGEEGTEGTIHLLCLAASSGVPLFCRSSRGGAPARQQLPFSVIGSLNGVHMFGQNLEVQLSSSRTEDTTVVWKSFHDSITLIVLSSEEGTSELRLERLLQMVFGAMVLLVGLEELTNIRNVERLKKELRASYRLIDSFLGDSELIGDLTQCVDCVVPPEGSLLQEALSGFAEAAGTAFISLVVSGRVVAATESWWRLGMPEAVLLPWLVGSLPPQAARDYPVYLPHGSPTVPHRLLTLTLLPDLELCLLCGPQPPLSQLDAQLLERWWQPLLEPLRGCLPLGTRALPAGFPLHTDILGLLLLHLELKRCLFTVEPSRDKEPSPEHRRRLLRSFYTLVTATHFPPEPGQPEEKAEEAIHRAQVARACYLVLGTEEPGTGWRLVALQLGPRRLLLLLSAQSPTYGLRGLATHTLHALTPLL", "length": 419 }, "evidence": [ { "id": "A0A8C2QBZ8", "url": "https://omabrowser.org/oma/group/A0A8C2QBZ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RH61-1", "protein_name": "Fuzzy planar cell polarity protein", "gene_name": "FUZ", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGEEGTEGMVHLLCLAASSGVPLFCRSSRGGAPARQQLPFSVIGSLNGVHMFGQNLEVQLSSARTEDTTVVWKSFHDSITLIVLSSEEGTSELRLERLLQMVFGAMVLLVGLEELTNIRNIERLKKELRASYRLIDSFLGNSELIGDLTQCVDCVVPPEGSLLQEALSGFAEAVGTAFVSLVVSGRVVAATESWWRLGMPEAVLLLWLVGSLPPQAARDYPVYLPHGSPMVPHRLLTLTLLPGLELCLLCGPRPPLSQLDAQLLERWWQPLLDPLRACLPLGPRALPGGFPLHADILGLLLLHLELKRCLFTVELSGDKEPSPGQRRRLLRSFYTLVTATYFPPEPGQPEKVEEAVHRAQVPRACYLVSGPEEPGIGWRLVALQLGPRRLLLLLSAQSPTHGLRGLATHTLHALTPLL", "length": 418 }, "evidence": [ { "id": "A0A8C2QBZ8", "url": "https://omabrowser.org/oma/group/A0A8C2QBZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O16868-1", "protein_name": "Protein fuzzy", "gene_name": "fuz", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSIYLLCLTTNGGLPVFTRKKGECENLPFSTVASLNGFHMFFKSLGIQLEATTTSKQQPIQNQAPADAEEWTYIWRDRESITLIVCGCGVGSEQLLQTLADLVFGAIGMFITRAAEMAHATLLDRLKKDAKKYVPIVDAILEAACAGTQLLGYTDCLLAAENAQLLQCLNEFSGHCGSLFCCLVVGHRIAVATEGWWDLDTRDRELLLFLLNSSSTMQHDVPVYLPVKSPHIAYRFVSIPVASNSALCVLCGAENASFRELHAHAMSAYRNEGNLLAAAERCVPRSLPEHLEIDGNVLAIILINRHTRKSLFTRNLNQSASVKRIIVGDLQRLDILKKFFDQTMDAVHQFETQSSSNKTTLVDQYSCSDYHKCYAHMDELGNVIFLLFVAAVPSHAMRFLAQRIHANILQEKSVCW", "length": 416 }, "evidence": [ { "id": "A0A8C2QBZ8", "url": "https://omabrowser.org/oma/group/A0A8C2QBZ8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q3B756-1", "protein_name": "Protein fuzzy homolog", "gene_name": "Fuz", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDDGPGSTVHLLCLAASSGVPLFCRSSSGGAPSRQQLPFSVIGSLNGVHMFGQNLDVQLNSARTEDTTVVWKNFHDSITLIALSSEEGTSELKLERMLHMVFGAMVLIVGLEELTNIRNVERLKKELRASYCLIDSFLGNSELIGDLTQCVDCVIPPEGSVMQETLSGFAEATGTAFVSLLVSGRVVAATDGWWRLGMPEAVLLPWLVGSLPPQAARDYPVYLPHGSPTVPHRLLTLTLLRGLELCLLCGPRPPLGELDPQLLERWWQPLLEPLRACLPLGPRALPDGFPLHSDILGLLLLHLELRRCLFTVEPSKDKEPSPEQRRRLLRNFYTLVATTHFPPEPGPAEKQEDTVHPAQTPRACYLVLGPGMGWQLVAVQLGLRLLLLMLSPQTPTHGLRSLATHTLQALTPLL", "length": 415 }, "evidence": [ { "id": "A0A8C2QBZ8", "url": "https://omabrowser.org/oma/group/A0A8C2QBZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UYI6-1", "protein_name": "Protein fuzzy homolog", "gene_name": "Fuz", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDEGPGSPVHLLCLAASSGVPLFCRSSSGGAPSRQQLPFSVIGSLNGVHMFGQNLDVQLNSARTEDTTVVWKNFHDSITLIVLSSEEGTSELRLERMLHMVFGAMVLIVGLEELTNIRNVERLKKELRASYCLIDSFLGNSELIGDLTQCVDCVIPPEGSAMQETLSGFAEATGTAFVSLLVSGRVVAATEGWWRLGMPEAVLLPWLVGSLPPQAARDYPVYLPHGSPTVPHRLLTLTLLRGLELCLLCGPRPPLGQLDPQLMERWWQPLLEPLRACLPLGPRALPEGFPLHSDILGLLLLHLELRRCLFTMEPSKDKEPSPEQRRRLLRNFYTLVATTHFPPEPGPAEKQEDTVYPAQMPRACYLVLGPGMGWQLVAVQLGLRLLLLLLSPHTPTHGLRSLATRTLQALTPLL", "length": 415 }, "evidence": [ { "id": "A0A8C2QBZ8", "url": "https://omabrowser.org/oma/group/A0A8C2QBZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BT04-1", "protein_name": "Protein fuzzy homolog", "gene_name": "FUZ", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGEEGTGGTVHLLCLAASSGVPLFCRSSRGGAPARQQLPFSVIGSLNGVHMFGQNLEVQLSSARTENTTVVWKSFHDSITLIVLSSEVGISELRLERLLQMVFGAMVLLVGLEELTNIRNVERLKKDLRASYCLIDSFLGDSELIGDLTQCVDCVIPPEGSLLQEALSGFAEAAGTTFVSLVVSGRVVAATEGWWRLGTPEAVLLPWLVGSLPPQTARDYPVYLPHGSPTVPHRLLTLTLLPSLELCLLCGPSPPLSQLYPQLLERWWQPLLDPLRACLPLGPRALPSGFPLHTDILGLLLLHLELKRCLFTVEPLGDKEPSPEQRRRLLRNFYTLVTSTHFPPEPGPPEKTEDEVYQAQLPRACYLVLGTEEPGTGVRLVALQLGLRRLLLLLSPQSPTHGLRSLATHTLHALTPLL", "length": 418 }, "evidence": [ { "id": "A0A8C2QBZ8", "url": "https://omabrowser.org/oma/group/A0A8C2QBZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8" } ], "pmid": "" }, { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8" } ], "pmid": "" }, { "name": "neural tube closure", "id": "GO:0001843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001843", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8" } ], "pmid": "" }, { "name": "positive regulation of cilium assembly", "id": "GO:0045724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045724", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QBZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8" }, { "id": "PF19036", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19036" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FUZ/MON1/HPS1 first Longin", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 137, "start_aa": "His", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2QBZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8" }, { "id": "PF19037", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19037" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FUZ/MON1/HPS1 second Longin", "eco_id": "ECO_0000259", "start_pos": 175, "end_pos": 269, "start_aa": "Gly", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2QBZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ8" }, { "id": "PF19038", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19038" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FUZ/MON1/HPS1 third Longin", "eco_id": "ECO_0000259", "start_pos": 296, "end_pos": 412, "start_aa": "Ile", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QDY7-1", "uniprot_ac": "A0A8C2QDY7", "uniprot_id": "A0A8C2QDY7_CRIGR", "mass": { "chemical_mass": 65488.0, "monoisotopic_mass": 65488.0 }, "refseq": { "ac": "XP_027246659", "name": "SLAIN motif-containing protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246659" }, "gene_names": [ { "name": "Slain2", "type": "recommended", "evidence": [ { "id": "A0A8C2QDY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDY7" } ] }, { "name": "Slain2", "type": "synonym", "evidence": [ { "id": "XP_027246659", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246659" } ] } ], "protein_names": [ { "name": "SLAIN motif-containing protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027246659", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246659" }, { "id": "A0A8C2QDY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDY7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027246659", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246659" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDY7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slain2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDY7", "locus": {} } ], "crossref": [ { "id": "100754053", "url": "https://www.ncbi.nlm.nih.gov/gene/100754053", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754053", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754053", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QDY7", "url": "https://www.orthodb.org/?gene=A0A8C2QDY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22406", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22406", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22406:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22406:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15301", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15301", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027246659", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246659", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LM71", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LM71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LM71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LM71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QDY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QDY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDY7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDVNSNVNADQEVRKLQELVKKLEKQNEQLRSRSGAVQGAGLLGPGSPARAGVSTPCSGAASPRGFPLGLGTKVSGVAGSGPRRTSSEDLRDATSLLAAGEGGLLDEVEPLRPDELERLSGWEEEEESWLYSSPKKKLTPMQKSVSPLVWCRQVLDYPSPDVECAKKSLIHKLDQTMSALKRQNLYNNPFNSVSYTSPYSPNASSPYSSGFNSPSSTPVRPPIVKQLILPGNSGNFKNSSDRNPPLSPQSSIDSELSASELDEDSIGSNYKLNDVTDVQILARMQEESLRQEYAATTSRRSSGSSCNSTRRGTFSDQELDAQSLDDEDDSVHHAVYPAVSRFSPSPRNSPRPSPKQSPRNSPRSRSPARGIEYSRVSPQPMISRLQQPRLSLQGHPTDLQTSNVKNEEKLRRSLPNLSRTSNTQVDSVKSSRSDSNFQVPNGGIPRMQPQASATSQRLKNLPRTSLKAKQLLPTSSTKRVPSPGKFRSPAAPSPLALRQPVKAFSNHNSGSGGQETTQFTQTTSSPGPPVVQNTAPANPSSNINSATLTRPAGTTAMRSGLPRPSAPSAGGIPVPRSKLAQPVRRSLPAPKTYGSMKDDSWKDGCY", "length": 607, "header": "tr|A0A8C2QDY7-1|A0A8C2QDY7_CRIGR Isoform 1 of SLAIN motif-containing protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Slain2 PE=3 SV=1 CANONICAL=A0A8C2QDY7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LM71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDY7/entry#A0A8C2LM71-1", "sequence": { "sequence": "MEDVNSNVNADQEVRKLQELVKKLEKQNEQLRSRSGAVQGAGLLGPGSPARAGVSTPCSGAASPRGFPLGLGTKVSGVAGSGPRRTSSEDLRDATSLLAAGEGGLLDEVEPLRPDELERLSGWEEEEESWLYSSPKKKLTPMQKSVSPLVWCRQVLDYPSPDVECAKKSLIHKLDQTMSALKRQNLYNNPFNSVSYTSPYSPNASSPYSSGFNSPSSTPVRPPIVKQLILPGNSGNFKNSSDRNPPLSPQSSIDSELSASELDEDSIGSNYKLNDVTDVQILARMQEESLRQEYAATTSRRSSGSSCNSTRRGTFSDQELDAQSLDDEDDSVHHAVYPAVSRFSPSPRNSPRPSPKQSPRNSPRSRSPARGIEYSRVSPQPMISRLQQPRLSLQGHPTDLQTSNVKNEEKLRRSLPNLSRTSNTQVDSVKSSRSDSNFQVPNGGIPRMQPQASAIPSPGKFRSPAAPSPLALRQPVKAFSNHNSGSGGQETTQFTQTTSSPGPPVVQNTAPANPSSNINSATLTRPAGTTAMRSGLPRPSAPSAGGIPVPRSKLAQPVRRSLPAPKTYGSMKDDSWKDGCY", "length": 581, "header": "tr|A0A8C2LM71-1|A0A8C2QDY7_CRIGR Computationally mapped isoform of SLAIN motif-containing protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Slain2 PE=3 SV=1 CANONICAL=A0A8C2QDY7-1" }, "locus": {} }, { "isoform_ac": "A0A8C2QDY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDY7/entry#A0A8C2QDY7-1", "sequence": { "sequence": "MEDVNSNVNADQEVRKLQELVKKLEKQNEQLRSRSGAVQGAGLLGPGSPARAGVSTPCSGAASPRGFPLGLGTKVSGVAGSGPRRTSSEDLRDATSLLAAGEGGLLDEVEPLRPDELERLSGWEEEEESWLYSSPKKKLTPMQKSVSPLVWCRQVLDYPSPDVECAKKSLIHKLDQTMSALKRQNLYNNPFNSVSYTSPYSPNASSPYSSGFNSPSSTPVRPPIVKQLILPGNSGNFKNSSDRNPPLSPQSSIDSELSASELDEDSIGSNYKLNDVTDVQILARMQEESLRQEYAATTSRRSSGSSCNSTRRGTFSDQELDAQSLDDEDDSVHHAVYPAVSRFSPSPRNSPRPSPKQSPRNSPRSRSPARGIEYSRVSPQPMISRLQQPRLSLQGHPTDLQTSNVKNEEKLRRSLPNLSRTSNTQVDSVKSSRSDSNFQVPNGGIPRMQPQASATSQRLKNLPRTSLKAKQLLPTSSTKRVPSPGKFRSPAAPSPLALRQPVKAFSNHNSGSGGQETTQFTQTTSSPGPPVVQNTAPANPSSNINSATLTRPAGTTAMRSGLPRPSAPSAGGIPVPRSKLAQPVRRSLPAPKTYGSMKDDSWKDGCY", "length": 607, "header": "tr|A0A8C2QDY7-1|A0A8C2QDY7_CRIGR Isoform 1 of SLAIN motif-containing protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Slain2 PE=3 SV=1 CANONICAL=A0A8C2QDY7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LM71", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LM71" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LM71", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LM71" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754053", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754053", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDY7" } ], "pmid": "" }, { "name": "positive regulation of microtubule polymerization", "id": "GO:0031116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031116", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDY7" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDY7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "microtubule plus-end", "id": "GO:0035371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035371", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDY7" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDY7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDY7" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDY7" } ], "pmid": "" }, { "name": "ciliary tip", "id": "GO:0097542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097542", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H2G8-1", "uniprot_ac": "A0A9J7H2G8", "uniprot_id": "A0A9J7H2G8_CRIGR", "mass": { "chemical_mass": 61244.0, "monoisotopic_mass": 61244.0 }, "refseq": { "ac": "XP_016834265", "name": "glycosyltransferase-like domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834265" }, "gene_names": [ { "name": "Gtdc1", "type": "recommended", "evidence": [ { "id": "A0A9J7H2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8" } ] }, { "name": "Gtdc1", "type": "synonym", "evidence": [ { "id": "XP_016834265", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834265" } ] } ], "protein_names": [ { "name": "tRNA-queuosine alpha-mannosyltransferase", "type": "recommended", "evidence": [ { "id": "A0A9J7H2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.110", "type": "synonym", "evidence": [ { "id": "A0A9J7H2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8/entry#names_and_taxonomy" } ] }, { "name": "Glycosyltransferase-like domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A9J7H2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8/entry#names_and_taxonomy" } ] }, { "name": "glycosyltransferase-like domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016834265", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834265" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614558.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016834265", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834265" } ] }, { "annotation": "Glycosyltransferase that specifically catalyzes mannosylation of cytoplasmic tRNA(Asp) modified with queuosine at position 34 (queuosine(34)). Mannosylates the cyclopentene moiety of queuosine(34) in tRNA(Asp) to form mannosyl-queuosine(34). Mannosylation of queuosine(34) in tRNA(Asp) is required to slow-down elongation at cognate codons, GAC and GAU, thereby regulating protein translation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K6Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6Q6#function" }, { "database": "UniProtKB", "id": "ARBA00045402", "url": "https://www.uniprot.org/uniprotkb/ARBA00045402#function" }, { "database": "UniProtKB", "id": "A0A8C2M6H8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6H8#function" }, { "database": "UniProtKB", "id": "A0A9J7H2G8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8#function" }, { "database": "UniProtKB", "id": "A0A9J7H2H9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H9#function" }, { "database": "UniProtKB", "id": "A0A9J7H039", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H039#function" }, { "database": "UniProtKB", "id": "A0A9J7H049", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H049#function" }, { "database": "UniProtKB", "id": "A0A9J7H1R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1R0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2G8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gtdc1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8", "locus": {} } ], "crossref": [ { "id": "A0A9J7H2G8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H2G8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01635", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01635", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752161", "url": "https://www.ncbi.nlm.nih.gov/gene/100752161", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752161", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752161", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2M6H8", "url": "https://www.orthodb.org/?gene=A0A8C2M6H8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H177", "url": "https://www.orthodb.org/?gene=A0A9J7H177", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H2G8", "url": "https://www.orthodb.org/?gene=A0A9J7H2G8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H2H9", "url": "https://www.orthodb.org/?gene=A0A9J7H2H9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7K6Q6", "url": "https://www.orthodb.org/?gene=A0A9J7K6Q6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13615:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13615:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00534", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00534", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016834265", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834265", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12885", "url": "https://www.rhea-db.org/rhea/12885", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2M6H8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M6H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6H8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H039", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H039", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H039-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H039-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H049", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H049", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H049-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H049-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H177", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H177", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H177-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H177-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2G8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2H9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUG8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K6Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6Q6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K6Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6Q6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKDFGLKSQSKLNLIFLYSISSRPWEEVTQTILLSEEYIWPQGVEDLDTYPQAFFHLFWLRLEVITLSVKGLKRPMSILIIEAFYGGSHRQLVELLQEELDNCVLYTLPAKKWHWRARTAALYFSQSIPSSEHYRTLFASSVLNLAELTALRPDLGKLKKILYFHENQLVYPVKKYQERDFQYGYNQILSCLVADVVVFNSIFNMESFLTSIGKFLKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKIAHLRRMLSLNGNDVAALSVMLPSQPEQRNSKKFLENFKSKSEEHPGLDAGQETLTNPSIKKSGLEKSSLSEDNSGCLPVSKNLALDPSSLFCGADDQQRPLHIAWPHRWEHDKDPESFFKVLMQLKDLGLNFLVSVLGETFTDVPDIFSEAKKALGSSVLHWGYLPCKEDYFRVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQSFCKRPDIIRKHLYKGEVAPFSWAALHGKFRSLLTTEPREDL", "length": 532, "header": "tr|A0A9J7H2G8-1|A0A9J7H2G8_CRIGR Isoform 1 of tRNA-queuosine alpha-mannosyltransferase OS=Cricetulus griseus OX=10029 GN=Gtdc1 PE=3 SV=1 CANONICAL=A0A9J7H2G8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M6H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8/entry#A0A8C2M6H8-1", "sequence": { "sequence": "MSILIIEAFYGGSHRQLVELLQEELDNCVLYTLPAKKWHWRARTAALYFSQSIPSSEHYRTLFASSVLNLAELTALRPDLGKLKKILYFHENQLVYPVKKYQERDFQYGYNQILSCLVADVVVFNSIFNMESFLTSIGKFLKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKIAHLRRMLSLNGNDVAALSVMLPSQPEQRNSKKFLENFKSKSEEHPGLDAGQETLTNPSIKKSGLEKSSLSEDNSGCLPVSKNLALDPSSLFCGADDQQRPLHIAWPHRWEHDKDPESFFKVLMQLKDLGLNFLVSVLGETFTDVPDIFSEAKKALGSSVLHWGYLPCKEDYFRVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQSFCKRPDIIRKHLYKGEVAPFSWAALHGKFRSLLTTEPREDL", "length": 456, "header": "tr|A0A8C2M6H8-1|A0A9J7H2G8_CRIGR Computationally mapped isoform of tRNA-queuosine alpha-mannosyltransferase OS=Cricetulus griseus OX=10029 GN=Gtdc1 PE=3 SV=1 CANONICAL=A0A9J7H2G8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H039-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8/entry#A0A9J7H039-1", "sequence": { "sequence": "MFFFFFFLPPVSQCGNGKVTQTILLSEEYIWPQGVEDLDTYPQAFFHLFWLRLEVITLSVKGLKRPMSILIIEAFYGGSHRQLVELLQEELDNCVLYTLPAKKWHWRARTAALYFSQSIPSSEHYRTLFASSVLNLAELTALRPDLGKLKKILYFHENQLVYPVKKYQERDFQYGYNQILSCLVADVVVFNSIFNMESFLTSIGKFLKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKIAHLRRMLSLNGNDVAALSVMLPSQPEQRNSKKFLENFKSKSEEHPGLDAGQETLTNPSIKKSGLEKSSLSEDNSGCLPVSKNLALDPSSLFCGADDQQRPLHIAWPHRWEHDKDPESFFKVLMQLKDLGLNFLVSVLGETFTDVPDIFSEAKKALGSSVLHWGYLPCKEDYFRVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQSFCKRPDIIRKHLYKGEVAPFSWAALHGKFRSLLTTEPREDL", "length": 522, "header": "tr|A0A9J7H039-1|A0A9J7H039_CRIGR Computationally mapped isoform of tRNA-queuosine alpha-mannosyltransferase OS=Cricetulus griseus OX=10029 GN=Gtdc1 PE=3 SV=1 CANONICAL=A0A9J7H2G8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H049-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8/entry#A0A9J7H049-1", "sequence": { "sequence": "MTKDFGLKSQSKLNLIFLYSISSRPWEEVTQTILLSEEYIWPQGVEDLDTYPQAFFHLFWLRLEVITLSVKGLKRPMSILIIEAFYGGSHRQLVELLQEELDNCVLYTLPAKKWHWRARTAALYFSQSIPSSEHYRTLFASSVLNLAELTALRPDLGKLKKILYFHENQLVYPVKKYQERDFQYGYNQILSCLVADVVVFNSIFNMESFLTSIGKFLKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKIAHLRRMLSLNGNDVAALSVMLPSQPEQRNSKKFLENFKSKSEEHPGLDAGQETLTNPSIKKSGLEKSSLSEDNSGCLPVSKNLALDPSSLFCGADDQQRPLHIAWPHRWEHDKDPESFFKVLMQLKDLGLNFLVSVLGETFTDVPGGRP", "length": 406, "header": "tr|A0A9J7H049-1|A0A9J7H049_CRIGR Computationally mapped isoform of tRNA-queuosine alpha-mannosyltransferase OS=Cricetulus griseus OX=10029 GN=Gtdc1 PE=3 SV=1 CANONICAL=A0A9J7H2G8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H177-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8/entry#A0A9J7H177-1", "sequence": { "sequence": "MHYASAVSLSCIPNSLCPLFLLPLYSYIKPRRMADWTYPYQINYKRFMPKHKIAHLRRMLSLNGNDVAALSVMLPSQPEQRNSKKFLENFKSKSEEHPGLDAGQETLTNPSIKKSGLEKSSLSEDNSGCLPVSKNLALDPSSLFCGADDQQRPLHIAWPHRWEHDKDPESFFKVLMQLKDLGLNFLVSVLGETFTDVPDIFSEAKKALGSSVLHWGYLPCKEDYFRVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQSFCKRPDIIRKHLYKGEVAPFSWAALHGKFRSLLTTEPREDL", "length": 328, "header": "tr|A0A9J7H177-1|A0A9J7H177_CRIGR Computationally mapped isoform of Glycosyltransferase-like domain-containing protein 1 isoform X7 OS=Cricetulus griseus OX=10029 GN=Gtdc1 PE=4 SV=1 CANONICAL=A0A9J7H2G8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8/entry#A0A9J7H1R0-1", "sequence": { "sequence": "MTKDFGLKSQSKLNLIFLYSISSRPWEEVTQTILLSEEYIWPQGVEDLDTYPQAFFHLFWLRLEVITLSVKGLKRPMSILIIEAFYGGSHRQLVELLQEELDNCVLYTLPAKKWHWRARTAALYFSQSIPSSEHYRTLFASSVLNLAELTALRPDLGKLKKILYFHENQLVYPVKKYQERDFQYGYNQILSCLVADVVVFNSIFNMESFLTSIGKFLKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKIAHLRRMLSLNGNDVAALSVMLPSQPEQRNSKKFLENFKSKSEEHPGLDAGQETLTNPSIKKSGLEKSSLSEDNSGCLPVSKNLALDPSSLFCGADDQQRPLHIAWPHRWEHDKDPESFFKVLMQLKDLGLNFLVSVLGETFTDVPAEYLYSTPEQLSKRLQSFCKRPDIIRKHLYKGEVAPFSWAALHGKFRSLLTTEPREDL", "length": 460, "header": "tr|A0A9J7H1R0-1|A0A9J7H1R0_CRIGR Computationally mapped isoform of tRNA-queuosine alpha-mannosyltransferase OS=Cricetulus griseus OX=10029 GN=Gtdc1 PE=3 SV=1 CANONICAL=A0A9J7H2G8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8/entry#A0A9J7H1S3-1", "sequence": { "sequence": "MQGIPGSNIGRFMPKHKIAHLRRMLSLNGNDVAALSVMLPSQPEQRNSKKFLENFKSKSEEHPGLDAGQETLTNPSIKKSGLEKSSLSEDNSGCLPVSKNLALDPSSLFCGADDQQRPLHIAWPHRWEHDKDPESFFKVLMQLKDLGLNFLVSVLGETFTDVPDIFSEAKKALGSSVLHWGYLPCKEDYFRVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQSFCKRPDIIRKHLYKGEVAPFSWAALHGKFRSLLTTEPREDL", "length": 293, "header": "tr|A0A9J7H1S3-1|A0A9J7H1S3_CRIGR Computationally mapped isoform of Glycosyltransferase-like domain-containing protein 1 isoform X10 OS=Cricetulus griseus OX=10029 GN=Gtdc1 PE=4 SV=1 CANONICAL=A0A9J7H2G8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8/entry#A0A9J7H2G8-1", "sequence": { "sequence": "MTKDFGLKSQSKLNLIFLYSISSRPWEEVTQTILLSEEYIWPQGVEDLDTYPQAFFHLFWLRLEVITLSVKGLKRPMSILIIEAFYGGSHRQLVELLQEELDNCVLYTLPAKKWHWRARTAALYFSQSIPSSEHYRTLFASSVLNLAELTALRPDLGKLKKILYFHENQLVYPVKKYQERDFQYGYNQILSCLVADVVVFNSIFNMESFLTSIGKFLKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKIAHLRRMLSLNGNDVAALSVMLPSQPEQRNSKKFLENFKSKSEEHPGLDAGQETLTNPSIKKSGLEKSSLSEDNSGCLPVSKNLALDPSSLFCGADDQQRPLHIAWPHRWEHDKDPESFFKVLMQLKDLGLNFLVSVLGETFTDVPDIFSEAKKALGSSVLHWGYLPCKEDYFRVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQSFCKRPDIIRKHLYKGEVAPFSWAALHGKFRSLLTTEPREDL", "length": 532, "header": "tr|A0A9J7H2G8-1|A0A9J7H2G8_CRIGR Isoform 1 of tRNA-queuosine alpha-mannosyltransferase OS=Cricetulus griseus OX=10029 GN=Gtdc1 PE=3 SV=1 CANONICAL=A0A9J7H2G8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8/entry#A0A9J7H2H9-1", "sequence": { "sequence": "MMMSISFGKFSECSLQLRTLFASSVLNLAELTALRPDLGKLKKILYFHENQLVYPVKKYQERDFQYGYNQILSCLVADVVVFNSIFNMESFLTSIGKFLKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKIAHLRRMLSLNGNDVAALSVMLPSQPEQRNSKKFLENFKSKSEEHPGLDAGQETLTNPSIKKSGLEKSSLSEDNSGCLPVSKNLALDPSSLFCGADDQQRPLHIAWPHRWEHDKDPESFFKVLMQLKDLGLNFLVSVLGETFTDVPDIFSEAKKALGSSVLHWGYLPCKEDYFRVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQSFCKRPDIIRKHLYKGEVAPFSWAALHGKFRSLLTTEPREDL", "length": 414, "header": "tr|A0A9J7H2H9-1|A0A9J7H2H9_CRIGR Computationally mapped isoform of tRNA-queuosine alpha-mannosyltransferase OS=Cricetulus griseus OX=10029 GN=Gtdc1 PE=3 SV=1 CANONICAL=A0A9J7H2G8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JUG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8/entry#A0A9J7JUG8-1", "sequence": { "sequence": "MQNGGGECSLVENHGLPFLWRAEISECLDRFMPKHKIAHLRRMLSLNGNDVAALSVMLPSQPEQRNSKKFLENFKSKSEEHPGLDAGQETLTNPSIKKSGLEKSSLSEDNSGCLPVSKNLALDPSSLFCGADDQQRPLHIAWPHRWEHDKDPESFFKVLMQLKDLGLNFLVSVLGETFTDVPDIFSEAKKALGSSVLHWGYLPCKEDYFRVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQSFCKRPDIIRKHLYKGEVAPFSWAALHGKFRSLLTTEPREDL", "length": 312, "header": "tr|A0A9J7JUG8-1|A0A9J7H2G8_CRIGR Computationally mapped isoform of tRNA-queuosine alpha-mannosyltransferase OS=Cricetulus griseus OX=10029 GN=Gtdc1 PE=3 SV=1 CANONICAL=A0A9J7H2G8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K6Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8/entry#A0A9J7K6Q6-1", "sequence": { "sequence": "MSHIFIDLGRVWYQQELYQLCEQLSKGLKRPMSILIIEAFYGGSHRQLVELLQEELDNCVLYTLPAKKWHWRARTAALYFSQSIPSSEHYRTLFASSVLNLAELTALRPDLGKLKKILYFHENQLVYPVKKYQERDFQYGYNQILSCLVADVVVFNSIFNMESFLTSIGKFLKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKIAHLRRMLSLNGNDVAALSVMLPSQPEQRNSKKFLENFKSKSEEHPGLDAGQETLTNPSIKKSGLEKSSLSEDNSGCLPVSKNLALDPSSLFCGADDQQRPLHIAWPHRWEHDKDPESFFKVLMQLKDLGLNFLVSVLGETFTDVPDIFSEAKKALGSSVLHWGYLPCKEDYFRVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQSFCKRPDIIRKHLYKGEVAPFSWAALHGKFRSLLTTEPREDL", "length": 487, "header": "tr|A0A9J7K6Q6-1|A0A9J7H2G8_CRIGR Computationally mapped isoform of tRNA-queuosine alpha-mannosyltransferase OS=Cricetulus griseus OX=10029 GN=Gtdc1 PE=3 SV=1 CANONICAL=A0A9J7H2G8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K6Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6Q6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K6Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6Q6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752161", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752161", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2G8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2G8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2G8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8" } ], "pmid": "" }, { "name": "tRNA wobble guanine modification", "id": "GO:0002099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002099", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2G8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "tRNA-queuosine(34) beta-mannosyltransferase activity", "id": "GO:0016438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016438", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2G8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2G8" } ], "pmid": "" }, { "name": 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"https://www.uniprot.org/uniprotkb/A0A9J7JZ88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZ88-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZ88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K0G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K0G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0G5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBF3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSPVDPGARQALRKKPPERTPEDLNTIYSYLHGMEILSNLREHQLRLMSARARYERYNGNQMLFCSETIARCWYILLSGSVLVKDSMVLPPCRPQIDYFLASTPPGFGKQFGGKRGCDCLVLEPSEMIVVENSKDNEDSILQREIPARQSRRRFRKINYKGERQTITDGVDVNNYLSLPADLTKMHLTDNPHPQVTHVSSSQSGCSIASDSGSSSLSDIYQATESEVGDVDLTRLPEGPVDSEDEEDEEEEIDRTDPLQGRDLVRECLEKEPADKTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAVILEDGQELDSWYVILNGTVEITHPDGKIENLFMGNSFGIVPTLDKQHMHGVVRTKVDDCQFVCIAQQDYWRILNHVEKNTHKVEEEGEIVMVHEHRELDRSGTRKGHIVIKATPERLIMHLIEEHSIVDPTYIEDFLLTYRTFLESPLDVGIKLLEWFKIDSLRDKVTRIVLLWVNNHFNDFEGDPAMTRFLEEFEKNLEDTKMNGHLRLLNIACAAKAKWRQVVLQKASRESPLHFILNGGSEKGFGVFVEGVEPGSKAADAGLKRGDQIMEVNGQNFENITFVKALEILRNNTHLALTVKTNIFVFKELLSRTEQEKSGIPHIPKIAEKKSNRHSIQDVPGDIEQIPQEKGNKKVKANTVSGGRNKIRKILDKTRFSILPPKLFSDGGLSQSQDDSIVGTRHCRHSLAIMPIPGTLSSSSPDLLQPTTSMLDFSNPSDIPDQVIRVFKADQQSCYIIISKDTTAKEVVCQAIQEFGLTGTSETYSLCEVSVTPEGVIKQRRLPDQFSKLADRIQLNGRYYLKNNMETETLCSDEDAQELLKESQLSMLQLSTIEVATQLSMRDFDLFRNIEPTEYIDDLFKLDSKTGNTHLKQFEDIVNQETFWVASEILSESNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRGTWEKLPSKYEKHLQDLQDLFDPSRNMAKYRNILSSQSMQPPIIPLFPVVKKDMTFLHEGNDSKVDGLVNFEKLRMIAKEIRHIVRMTSANMDPAMMFRQRKKRWRSLGSLSQGSTNSNMLDVQGGAHKKRARRSSLLNAKKLYEDAQMARKVKQYLSSLDIDTDEEKFQMISLQWEPAYGTLTKNLTEKKSAKSSEMSPVPLRSGGQTSKVHLHQPHRVSQVLQVPAVNLHPIRKRGQAKDHVLSTSLSQKGLGPTEEVSGKKHTEDTVSVASSLHSSPPASPQSSPRKGYTLIPSAKSDNLSDSSHSEISSRSSIVSNCSVDSMSAALQEERCSSHTLAVPELTAGAFEKTDHPSGIREHSQLGHGWMLSKPSLIKGVAVSSSLSSEEMSHEHVVLEAADSGRGSWTSCSSSSHDNFQSLPNPKSWDFLNTYRHTHLDDPIAEVEPTDCEPCACPKSCSRTCGQCKGSLETSQLRQSWASSSSLSDTYEPNYGTVKRRVLESAPSEAPDGLEPRDTTDPIYKTVTSSTDRGLIVYCVTSPKKGDRYREPPPTPPGYLGISLADLKEGPHPHLKPPDYSVAVQRSKMMFNSLSRLPPAPPSGHALAWVPSKTGSQPHRHSLQPSHPKLADVADADSEADENEQVSAV", "length": 1627, "header": "tr|A0A9J7H4E5-1|A0A9J7H4E5_CRIGR Isoform 1 of Rap guanine nucleotide exchange factor 6 isoform X10 OS=Cricetulus griseus OX=10029 GN=Rapgef6 PE=3 SV=1 CANONICAL=A0A9J7H4E5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MHB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5/entry#A0A8C2MHB3-1", "sequence": { "sequence": "MNSPVDPGARQALRKKPPERTPEDLNTIYSYLHGMEILSNLREHQLRLMSARARYERYNGNQMLFCSETIARCWYILLSGSVLVKDSMVLPPCSFGKQFGGKRGCDCLVLEPSEMIVVENSKDNEDSILQREIPARQSRRRFRKINYKGERQTITDGVDVNNYLSLPADLTKMHLTDNPHPQVTHVSSSQSGCSIASDSGSSSLSDIYQATESEVGDVDLTRLPEGPVDSEDEEDEEEEIDRTDPLQGRDLVRECLEKEPADKTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAVILEDGQELDSWYVILNGTVEITHPDGKIENLFMGNSFGIVPTLDKQHMHGVVRTKVDDCQFVCIAQQDYWRILNHVEKNTHKVEEEGEIVMVHEHRELDRSGTRKGHIVIKATPERLIMHLIEEHSIVDPTYIEDFLLTYRTFLESPLDVGIKLLEWFKIDSLRDKVTRIVLLWVNNHFNDFEGDPAMTRFLEEFEKNLEDTKMNGHLRLLNIACAAKAKWRQVVLQKASRESPLHFILNGGSEKGFGVFVEGVEPGSKAADAGLKRGDQIMEVNGQNFENITFVKALEILRNNTHLALTVKTNIFVFKELLSRTEQEKSGIPHIPKIAEKKSNRHSIQDVPGDIEQIPQEKGNKKVKANTVSGGRNKIRKILDKTRFSILPPKLFSDGGLSQSQDDSIVGTRHCRHSLAIMPIPGTLSSSSPDLLQPTTSMLDFSNPSDIPDQVIRVFKADQQSCYIIISKDTTAKEVVCQAIQEFGLTGTSETYSLCEVSVTPEGVIKQRRLPDQFSKLADRIQLNGRYYLKNNMETETLCSDEDAQELLKESQLSMLQLSTIEVATQLSMRDFDLFRNIEPTEYIDDLFKLDSKTGNTHLKQFEDIVNQETFWVASEILSESNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRGTWEKLPSKYEKHLQDLQDLFDPSRNMAKYRNILSSQSMQPPIIPLFPVVKKDMTFLHEGNDSKVDGLVNFEKLRMIAKEIRHIVRMTSANMDPAMMFRQRKKRWRSLGSLSQGSTNSNMLDVQGGAHKKRARRSSLLNAKKLYEDAQMARKVKQYLSSLDIDTDEEKFQMISLQWEPAYGTLTKNLTEKKSAKSSEMSPVPLRSGGQTSKVHLHQPHRVSQVLQVPAVNLHPIRKRGQAKDHVLSTSLSQKGLGPTEEVSGKKHTEDTVSVASSLHSSPPASPQSSPRKGYTLIPSAKSDNLSDSSHSEISSRSSIVSNCSVDSMSAALQEERCSSHTLAVPELTAGAFEKTDHPSGIREHSQLGHGWMLSKPSLIKGVAVSSSLSSEEMSHEHVVLEAADSGRGSWTSCSSSSHDNFQSLPNPKSWDFLNTYRHTHLDDPIAEVEPTDCEPCACPKSCSRTCGQCKGSLETSQLRQSWASSSSLSDTYEPNYGTVKRRVLESAPSEAPDGLEPRDTTDPIYKTVTSSTDRGLIVYCVTSPKKGDRYREPPPTPPGYLGISLADLKEGPHPHLKPPDYSVAVQRSKMMFNSLSRLPPAPPSGHALAWVPSKTGSQPHRHSLQPSHPKLADVADADSEADENEQVSAV", "length": 1614, "header": "tr|A0A8C2MHB3-1|A0A9J7H4E5_CRIGR Computationally mapped isoform of Rap guanine nucleotide exchange factor 6 isoform X10 OS=Cricetulus griseus OX=10029 GN=Rapgef6 PE=3 SV=1 CANONICAL=A0A9J7H4E5-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MMT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5/entry#A0A8C2MMT8-1", "sequence": { "sequence": "MNSPVDPGARQALRKKPPERTPEDLNTIYSYLHGMEILSNLREHQLRLMSARARYERYNGNQMLFCSETIARCWYILLSGSVLVKDSMVLPPCSFGKQFGGKRGCDCLVLEPSEMIVVENSKDNEDSILQREIPARQSRRRFRKINYKGERQTITDGVDVNNYLSLPADLTKMHLTDNPHPQVTHVSSSQSGCSIASDSGSSSLSDIYQATESEVGDVDLTRLPEGPVDSEDEEDEEEEIDRTDPLQGRDLVRECLEKEPADKTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAVILEDGQELDSWYVILNGTVEITHPDGKIENLFMGNSFGIVPTLDKQHMHGVVRTKVDDCQFVCIAQQDYWRILNHVEKNTHKVEEEGEIVMVHEHRELDRSGTRKGHIVIKATPERLIMHLIEEHSIVDPTYIEDFLLTYRTFLESPLDVGIKLLEWFKIDSLRDKVTRIVLLWVNNHFNDFEGDPAMTRFLEEFEKNLEDTKMNGHLRLLNIACAAKAKWRQVVLQKASRESPLHFILNGGSEKGFGVFVEGVEPGSKAADAGLKRGDQIMEVNGQNFENITFVKALEILRNNTHLALTVKTNIFVFKELLSRTEQEKSGIPHIPKIAEKKSNRHSIQDVPGDIEQIPQEKGNKKVKANTVSGGRNKIRKILDKTRFSILPPKLFSDGGLSQSQDDSIVGTRHCRHSLAIMPIPGTLSSSSPDLLQPTTSMLDFSNPSDIPDQVIRVFKADQQSCYIIISKDTTAKEVVCQAIQEFGLTGTSETYSLCEVSVTPEGVIKQRRLPDQFSKLADRIQLNGRYYLKNNMETETLCSDEDAQELLKESQLSMLQLSTIEVATQLSMRDFDLFRNIEPTEYIDDLFKLDSKTGNTHLKQFEDIVNQETFWVASEILSESNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRGTWEKLPSKYEKHLQDLQDLFDPSRNMAKYRNILSSQSMQPPIIPLFPVVKKDMTFLHEGNDSKVDGLVNFEKLRMIAKEIRHIVRMTSANMDPAMMFRQRSLSQGSTNSNMLDVQGGAHKKRARRSSLLNAKKLYEDAQMARKVKQYLSSLDIDTDEEKFQMISLQWEPAYGTLTKNLTEKKSAKSSEMSPVPLRSGGQTSKVHLHQPHRVSQVLQVPAVNLHPIRKRGQAKDHVLSTSLSQKGLGPTEEVSGKKHTEDTVSVASSLHSSPPASPQSSPRKGYTLIPSAKSDNLSDSSHSEISSRSSIVSNCSVDSMSAALQEERCSSHTLAVPELTAGAFEKTDHPSGIREHSQLGHGWMLSKPSLIKGVAVSSSLSSEEMSHEHVVLEAADSGRGSWTSCSSSSHDNFQSLPNPKSWDFLNTYRHTHLDDPIAEVEPTDCEPCACPKSCSRTCGQCKGSLETSQLRQSWASSSSLSDTYEPNYGTVKRRVLESAPSEAPDGLEPRDTTDPIYKTVTSSTDRGLIVYCVTSPKKGDRYREPPPTPPGYLGISLADLKEGPHPHLKPPDYSVAVQRSKMMFNSLSRLPPAPPSGHALAWVPSKTGSQPHRHSLQPSHPKLADVADADSEADENEQVSAV", "length": 1606, "header": "tr|A0A8C2MMT8-1|A0A9J7H4E5_CRIGR Computationally mapped isoform of Rap guanine nucleotide exchange factor 6 isoform X10 OS=Cricetulus griseus OX=10029 GN=Rapgef6 PE=3 SV=1 CANONICAL=A0A9J7H4E5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H151-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5/entry#A0A9J7H151-1", "sequence": { "sequence": "MAFLVRCYANCLQPWASKLPADLTKMHLTDNPHPQVTHVSSSQSGCSIASDSGSSSLSDIYQATESEVGDVDLTRLPEGPVDSEDEEDEEEEIDRTDPLQGRDLVRECLEKEPADKTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAVILEDGQELDSWYVILNGTVEITHPDGKIENLFMGNSFGIVPTLDKQHMHGVVRTKVDDCQFVCIAQQDYWRILNHVEKNTHKVEEEGEIVMVHEHRELDRSGTRKGHIVIKATPERLIMHLIEEHSIVDPTYIEDFLLTYRTFLESPLDVGIKLLEWFKIDSLRDKVTRIVLLWVNNHFNDFEGDPAMTRFLEEFEKNLEDTKMNGHLRLLNIACAAKAKWRQVVLQKASRESPLHFILNGGSEKGFGVFVEGVEPGSKAADAGLKRGDQIMEVNGQNFENITFVKALEILRNNTHLALTVKTNIFVFKELLSRTEQEKSGIPHIPKIAEKKSNRHSIQDVPGDIEQIPQEKGNKKVKANTVSGGRNKIRKILDKTRFSILPPKLFSDGGLSQSQDDSIVGTRHCRHSLAIMPIPGTLSSSSPDLLQPTTSMLDFSNPSGNVSM", "length": 604, "header": "tr|A0A9J7H151-1|A0A9J7H151_CRIGR Computationally mapped isoform of Rap guanine nucleotide exchange factor 6 isoform X9 OS=Cricetulus griseus OX=10029 GN=Rapgef6 PE=4 SV=1 CANONICAL=A0A9J7H4E5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5/entry#A0A9J7H2B2-1", "sequence": { "sequence": "MNSPVDPGARQALRKKPPERTPEDLNTIYSYLHGMEILSNLREHQLRLMSARARYERYNGNQMLFCSETIARCWYILLSGSVLVKDSMVLPPCRPQIDYFLASTPPGFGKQFGGKRGCDCLVLEPSEMIVVENSKDNEDSILQREIPARQSRRRFRKINYKGERQTITDGVDVNNYLSLPADLTKMHLTDNPHPQVTHVSSSQSGCSIASDSGSSSLSDIYQATESEVGDVDLTRLPEGPVDSEDEEDEEEEIDRTDPLQGRDLVRECLEKEPADKTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAVILEDGQELDSWYVILNGTVEITHPDGKIENLFMGNSFGIVPTLDKQHMHGVVRTKVDDCQFVCIAQQDYWRILNHVEKNTHKVEEEGEIVMVHEHRELDRSGTRKGHIVIKATPERLIMHLIEEHSIVDPTYIEDFLLTYRTFLESPLDVGIKLLEWFKIDSLRDKVTRIVLLWVNNHFNDFEGDPAMTRFLEEFEKNLEDTKMNGHLRLLNIACAAKAKWRQVVLQKASRESPLHFILNGGSEKGFGVFVEGVEPGSKAADAGLKRGDQIMEVNGQNFENITFVKALEILRNNTHLALTVKTNIFVFKELLSRTEQEKSGIPHIPKIAEKKSNRHSIQDVPGDIEQIPQEKGNKKVKANTVSGGRNKIRKILDKTRFSILPPKLFSDGGLSQSQDDSIVGTRHCRHSLAIMPIPGTLSSSSPDLLQPTTSMLDFSNPSDIPDQVIRVFKADQQSCYIIISKDTTAKEVVCQAIQEFGLTGTSETYSLCEVSVTPEGVIKQRRLPDQFSKLADRIQLNGRYYLKNNMETETLCSDEDAQELLKESQLSMLQLSTIEVATQLSMRDFDLFRNIEPTEYIDDLFKLDSKTGNTHLKQFEDIVNQETFWVASEILSESNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRGTWEKLPSKYEKHLQDLQDLFDPSRNMAKYRNILSSQSMQPPIIPLFPVVKKDMTFLHEGNDSKVDGLVNFEKLRMIAKEIRHIVRMTSANMDPAMMFRQRKKRWRSLGSLSQGSTNSNMLDVQGGAHKKRARRSSLLNAKKLYEDAQMARKVKQYLSSLDIDTDEEKFQMISLQWEPAYGTLTKNLTEKKSAKSSEMSPVPLRSGGQTSKVHLHQPHRVSQVLQVPAVNLHPIRKRGQAKDHVLSTSLSQKGLGPTEEVSGKKHTEDTVSVASSLHSSPPASPQSSPRKVGSIITDHSIPLHLSGSSSSPPREPSTKISGQSCPGIGGVYLQKKILQITGSTAKRTDRTKKATEENRDRTSCENTTRKRMTSPFRRFRARTLSRERLVNSQKEDTDHNQATDSCEKVKDVGSNITDEKGSAICDSSSQGHSTTLSCFCTRFKHKRRKTL", "length": 1429, "header": "tr|A0A9J7H2B2-1|A0A9J7H2B2_CRIGR Computationally mapped isoform of Rap guanine nucleotide exchange factor 6 isoform X15 OS=Cricetulus griseus OX=10029 GN=Rapgef6 PE=3 SV=1 CANONICAL=A0A9J7H4E5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5/entry#A0A9J7H2Z9-1", "sequence": { "sequence": "MHLTDNPHPQVTHVSSSQSGCSIASDSGSSSLSDIYQATESEVGDVDLTRLPEGPVDSEDEEDEEEEIDRTDPLQGRDLVRECLEKEPADKTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAVILEDGQELDSWYVILNGTVEITHPDGKIENLFMGNSFGIVPTLDKQHMHGVVRTKVDDCQFVCIAQQDYWRILNHVEKNTHKVEEEGEIVMVHEHRELDRSGTRKGHIVIKATPERLIMHLIEEHSIVDPTYIEDFLLTYRTFLESPLDVGIKLLEWFKIDSLRDKVTRIVLLWVNNHFNDFEGDPAMTRFLEEFEKNLEDTKMNGHLRLLNIACAAKAKWRQVVLQKASRESPLHFILNGGSEKGFGVFVEGVEPGSKAADAGLKRGDQIMEVNGQNFENITFVKALEILRNNTHLALTVKTNIFVFKELLSRTEQEKSGIPHIPKIAEKKSNRHSIQDVPGDIEQIPQEKGNKKVKANTVSGGRNKIRKILDKTRFSILPPKLFSDGGLSQSQDDSIVGTRHCRHSLAIMPIPGTLSSSSPDLLQPTTSMLDFSNPSDIPDQVIRVFKADQQSCYIIISKDTTAKEVVCQAIQEFGLTGTSETYSLCEVSVTPEGVIKQRRLPDQFSKLADRIQLNGRYYLKNNMETETLCSDEDAQELLKESQLSMLQLSTIEVATQLSMRDFDLFRNIEPTEYIDDLFKLDSKTGNTHLKQFEDIVNQETFWVASEILSESNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRGTWEKLPSKYEKHLQDLQDLFDPSRNMAKYRNILSSQSMQPPIIPLFPVVKKDMTFLHEGNDSKVDGLVNFEKLRMIAKEIRHIVRMTSANMDPAMMFRQRKKRWRSLGSLSQGSTNSNMLDVQGGAHKKRARRSSLLNAKKLYEDAQMARKVKQYLSSLDIDTDEEKFQMISLQWEPAYGTLTKNLTEKKSAKSSEMSPVPLRSGGQTSKVHLHQPHRVSQVLQVPAVNLHPIRKRGQAKDHVLSTSLSQKGLGPTEEVSGKKHTEDTVSVASSLHSSPPASPQSSPRKGYTLIPSAKSDNLSDSSHSEISSRSSIVSNCSVDSMSAALQEERCSSHTLAVPELTAGAFEKTDHPSGIREHSQLGHGWMLSKPSLIKGVAVSSSLSSEEMSHEHVVLEAADSGRGSWTSCSSSSHDNFQSLPNPKSWDFLNTYRHTHLDDPIAEVEPTDCEPCACPKSCSRTCGQCKGSLETSQLRQSWASSSSLSDTYEPNYGTVKRRVLESAPSEAPDGLEPRDTTDPIYKTVTSSTDRGLIVYCVTSPKKGDRYREPPPTPPGYLGISLADLKEGPHPHLKPPDYSVAVQRSKMMFNSLSRLPPAPPSGHALAWVPSKTGSQPHRHSLQPSHPKLADVADADSEADENEQVSAV", "length": 1442, "header": "tr|A0A9J7H2Z9-1|A0A9J7H2Z9_CRIGR Computationally mapped isoform of Rap guanine nucleotide exchange factor 6 isoform X7 OS=Cricetulus griseus OX=10029 GN=Rapgef6 PE=3 SV=1 CANONICAL=A0A9J7H4E5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H4E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5/entry#A0A9J7H4E5-1", "sequence": { "sequence": "MNSPVDPGARQALRKKPPERTPEDLNTIYSYLHGMEILSNLREHQLRLMSARARYERYNGNQMLFCSETIARCWYILLSGSVLVKDSMVLPPCRPQIDYFLASTPPGFGKQFGGKRGCDCLVLEPSEMIVVENSKDNEDSILQREIPARQSRRRFRKINYKGERQTITDGVDVNNYLSLPADLTKMHLTDNPHPQVTHVSSSQSGCSIASDSGSSSLSDIYQATESEVGDVDLTRLPEGPVDSEDEEDEEEEIDRTDPLQGRDLVRECLEKEPADKTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAVILEDGQELDSWYVILNGTVEITHPDGKIENLFMGNSFGIVPTLDKQHMHGVVRTKVDDCQFVCIAQQDYWRILNHVEKNTHKVEEEGEIVMVHEHRELDRSGTRKGHIVIKATPERLIMHLIEEHSIVDPTYIEDFLLTYRTFLESPLDVGIKLLEWFKIDSLRDKVTRIVLLWVNNHFNDFEGDPAMTRFLEEFEKNLEDTKMNGHLRLLNIACAAKAKWRQVVLQKASRESPLHFILNGGSEKGFGVFVEGVEPGSKAADAGLKRGDQIMEVNGQNFENITFVKALEILRNNTHLALTVKTNIFVFKELLSRTEQEKSGIPHIPKIAEKKSNRHSIQDVPGDIEQIPQEKGNKKVKANTVSGGRNKIRKILDKTRFSILPPKLFSDGGLSQSQDDSIVGTRHCRHSLAIMPIPGTLSSSSPDLLQPTTSMLDFSNPSDIPDQVIRVFKADQQSCYIIISKDTTAKEVVCQAIQEFGLTGTSETYSLCEVSVTPEGVIKQRRLPDQFSKLADRIQLNGRYYLKNNMETETLCSDEDAQELLKESQLSMLQLSTIEVATQLSMRDFDLFRNIEPTEYIDDLFKLDSKTGNTHLKQFEDIVNQETFWVASEILSESNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRGTWEKLPSKYEKHLQDLQDLFDPSRNMAKYRNILSSQSMQPPIIPLFPVVKKDMTFLHEGNDSKVDGLVNFEKLRMIAKEIRHIVRMTSANMDPAMMFRQRKKRWRSLGSLSQGSTNSNMLDVQGGAHKKRARRSSLLNAKKLYEDAQMARKVKQYLSSLDIDTDEEKFQMISLQWEPAYGTLTKNLTEKKSAKSSEMSPVPLRSGGQTSKVHLHQPHRVSQVLQVPAVNLHPIRKRGQAKDHVLSTSLSQKGLGPTEEVSGKKHTEDTVSVASSLHSSPPASPQSSPRKGYTLIPSAKSDNLSDSSHSEISSRSSIVSNCSVDSMSAALQEERCSSHTLAVPELTAGAFEKTDHPSGIREHSQLGHGWMLSKPSLIKGVAVSSSLSSEEMSHEHVVLEAADSGRGSWTSCSSSSHDNFQSLPNPKSWDFLNTYRHTHLDDPIAEVEPTDCEPCACPKSCSRTCGQCKGSLETSQLRQSWASSSSLSDTYEPNYGTVKRRVLESAPSEAPDGLEPRDTTDPIYKTVTSSTDRGLIVYCVTSPKKGDRYREPPPTPPGYLGISLADLKEGPHPHLKPPDYSVAVQRSKMMFNSLSRLPPAPPSGHALAWVPSKTGSQPHRHSLQPSHPKLADVADADSEADENEQVSAV", "length": 1627, "header": "tr|A0A9J7H4E5-1|A0A9J7H4E5_CRIGR Isoform 1 of Rap guanine nucleotide exchange factor 6 isoform X10 OS=Cricetulus griseus OX=10029 GN=Rapgef6 PE=3 SV=1 CANONICAL=A0A9J7H4E5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JPZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5/entry#A0A9J7JPZ5-1", "sequence": { "sequence": "MLVYPAFWICTCKRLYGPSSLQVENSKDNEDSILQREIPARQSRRRFRKINYKGERQTITDGVDVNNYLSLPADLTKMHLTDNPHPQVTHVSSSQSGCSIASDSGSSSLSDIYQATESEVGDVDLTRLPEGPVDSEDEEDEEEEIDRTDPLQGRDLVRECLEKEPADKTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAVILEDGQELDSWYVILNGTVEITHPDGKIENLFMGNSFGIVPTLDKQHMHGVVRTKVDDCQFVCIAQQDYWRILNHVEKNTHKVEEEGEIVMVHEHRELDRSGTRKGHIVIKATPERLIMHLIEEHSIVDPTYIEDFLLTYRTFLESPLDVGIKLLEWFKIDSLRDKVTRIVLLWVNNHFNDFEGDPAMTRFLEEFEKNLEDTKMNGHLRLLNIACAAKAKWRQVVLQKASRESPLHFILNGGSEKGFGVFVEGVEPGSKAADAGLKRGDQIMEVNGQNFENITFVKALEILRNNTHLALTVKTNIFVFKELLSRTEQEKSGIPHIPKIAEKKSNRHSIQDVPGDIEQIPQEKGNKKVKANTVSGGRNKIRKILDKTRFSILPPKLFSDGGLSQSQDDSIVGTRHCRHSLAIMPIPGTLSSSSPDLLQPTTSMLDFSNPSDIPDQVIRVFKADQQSCYIIISKDTTAKEVVCQAIQEFGLTGTSETYSLCEVSVTPEGVIKQRRLPDQFSKLADRIQLNGRYYLKNNMETETLCSDEDAQELLKESQLSMLQLSTIEVATQLSMRDFDLFRNIEPTEYIDDLFKLDSKTGNTHLKQFEDIVNQETFWVASEILSESNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRGTWEKLPSKYEKHLQDLQDLFDPSRNMAKYRNILSSQSMQPPIIPLFPVVKKDMTFLHEGNDSKVDGLVNFEKLRMIAKEIRHIVRMTSANMDPAMMFRQRKKRWRSLGSLSQGSTNSNMLDVQGGAHKKRARRSSLLNAKKLYEDAQMARKVKQYLSSLDIDTDEEKFQMISLQWEPAYGTLTKNLTEKKSAKSSEMSPVPLRSGGQTSKVHLHQPHRVSQVLQVPAVNLHPIRKRGQAKDHVLSTSLSQKGLGPTEEVSGKKHTEDTVSVASSLHSSPPASPQSSPRKGYTLIPSAKSDNLSDSSHSEISSRSSIVSNCSVDSMSAALQEERCSSHTLAVPELTAGAFEKTDHPSGIREHSQLGHGWMLSKPSLIKGVAVSSSLSSEEMSHEHVVLEAADSGRGSWTSCSSSSHDNFQSLPNPKSWDFLNTYRHTHLDDPIAEVEPTDCEPCACPKSCSRTCGQCKGSLETSQLRQSWASSSSLSDTYEPNYGTVKRRVLESAPSEAPDGLEPRDTTDPIYKTVTSSTDRGLIVYCVTSPKKGDRYREPPPTPPGYLGISLADLKEGPHPHLKPPDYSVAVQRSKMMFNSLSRLPPAPPSGHALAWVPSKTGSQPHRHSLQPSHPKLADVADADSEADENEQVSAV", "length": 1519, "header": "tr|A0A9J7JPZ5-1|A0A9J7H4E5_CRIGR Computationally mapped isoform of Rap guanine nucleotide exchange factor 6 isoform X10 OS=Cricetulus griseus OX=10029 GN=Rapgef6 PE=3 SV=1 CANONICAL=A0A9J7H4E5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JZ88-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5/entry#A0A9J7JZ88-1", "sequence": { "sequence": "MNSPVDPGARQALRKKPPERTPEDLNTIYSYLHGMEILSNLREHQLRLMSARARYERYNGNQMLFCSETIARCWYILLSGSVLVKDSMVLPPCSFGKQFGGKRGCDCLVLEPSEMIVVENSKDNEDSILQREIPARQSRRRFRKINYKGERQTITDGVDVNNYLSLPADLTKMHLTDNPHPQVTHVSSSQSGCSIASDSGSSSLSDIYQATESEVGDVDLTRLPEGPVDSEDEEDEEEEIDRTDPLQGRDLVRECLEKEPADKTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAVILEDGQELDSWYVILNGTVEITHPDGKIENLFMGNSFGIVPTLDKQHMHGVVRTKVDDCQFVCIAQQDYWRILNHVEKNTHKVEEEGEIVMVHEHRELDRSGTRKGHIVIKATPERLIMHLIEEHSIVDPTYIEDFLLTYRTFLESPLDVGIKLLEWFKIDSLRDKVTRIVLLWVNNHFNDFEGDPAMTRFLEEFEKNLEDTKMNGHLRLLNIACAAKAKWRQVVLQKASRESPLHFILNGGSEKGFGVFVEGVEPGSKAADAGLKRGDQIMEVNGQNFENITFVKALEILRNNTHLALTVKTNIFVFKELLSRTEQEKSGIPHIPKIAEKKSNRHSIQDVPGDIEQIPQEKGNKKVKANTVSGGRNKIRKILDKTRFSILPPKLFSDGGLSQSQDDSIVGTRHCRHSLAIMPIPGTLSSSSPDLLQPTTSMLDFSNPSDIPDQVIRVFKADQQSCYIIISKDTTAKEVVCQAIQEFGLTGTSETYSLCEVSVTPEGVIKQRRLPDQFSKLADRIQLNGRYYLKNNMETETLCSDEDAQELLKESQLSMLQLSTIEVATQLSMRDFDLFRNIEPTEYIDDLFKLDSKTGNTHLKQFEDIVNQETFWVASEILSESNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRGTWEKLPSKYEKHLQDLQDLFDPSRNMAKYRNILSSQSMQPPIIPLFPVVKKDMTFLHEGNDSKVDGLVNFEKLRMIAKEIRHIVRMTSANMDPAMMFRQRSLSQGSTNSNMLDVQGGAHKKRARRSSLLNAKKLYEDAQMARKVKQYLSSLDIDTDEEKFQMISLQWEPAYGTLTKNLTEKKSAKSSEMSPVPLRSGGQTSKVHLHQPHRVSQVLQVPAVNLHPIRKRGQAKDHVLSTSLSQKGLGPTEEVSGKKHTEDTVSVASSLHSSPPASPQSSPRKVGSIITDHSIPLHLSGSSSSPPREPSTKISGQSCPGIGGVYLQKKILQITGSTAKRTDRTKKATEENRDRTSCENTTRKRMTSPFRRFRARTLSRERLVNSQKEDTDHNQATDSCEKVKDVGSNITDEKGSAICDSSSQGHSTTLSCFCTRFKHKRRKTL", "length": 1408, "header": "tr|A0A9J7JZ88-1|A0A9J7H4E5_CRIGR Computationally mapped isoform of Rap guanine nucleotide exchange factor 6 isoform X10 OS=Cricetulus griseus OX=10029 GN=Rapgef6 PE=3 SV=1 CANONICAL=A0A9J7H4E5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K0G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5/entry#A0A9J7K0G5-1", "sequence": { "sequence": "MNSPVDPGARQALRKKPPERTPEDLNTIYSYLHGMEILSNLREHQLRLMSARARYERYNGNQMLFCSETIARCWYILLSGSVLVKDSMVLPPCRPQIDYFLASTPPGFGKQFGGKRGCDCLVLEPSEMIVVENSKDNEDSILQREIPARQSRRRFRKINYKGERQTITDGVDVNNYLSLPADLTKMHLTDNPHPQVTHVSSSQSGCSIASDSGSSSLSDIYQATESEVGDVDLTRLPEGPVDSEDEEDEEEEIDRTDPLQGRDLVRECLEKEPADKTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAVILEDGQELDSWYVILNGTVEITHPDGKIENLFMGNSFGIVPTLDKQHMHGVVRTKVDDCQFVCIAQQDYWRILNHVEKNTHKVEEEGEIVMVHEHRELDRSGTRKGHIVIKATPERLIMHLIEEHSIVDPTYIEDFLLTYRTFLESPLDVGIKLLEWFKIDSLRDKVTRIVLLWVNNHFNDFEGDPAMTRFLEEFEKNLEDTKMNGHLRLLNIACAAKAKWRQVVLQKASRESPLHFILNGGSEKGFGVFVEGVEPGSKAADAGLKRGDQIMEVNGQNFENITFVKALEILRNNTHLALTVKTNIFVFKELLSRTEQEKSGIPHIPKIAEKKSNRHSIQDVPGDIEQIPQEKGNKKVKANTVSGGRNKIRKILDKTRFSILPPKLFSDGGLSQSQDDSIVGTRHCRHSLAIMPIPGTLSSSSPDLLQPTTSMLDFSNPSDIPDQVIRVFKADQQSCYIIISKDTTAKEVVCQAIQEFGLTGTSETYSLCEVSVTPEGVIKQRRLPDQFSKLADRIQLNGRYYLKNNMETETLCSDEDAQELLKESQLSMLQLSTIEVATQLSMRDFDLFRNIEPTEYIDDLFKLDSKTGNTHLKQFEDIVNQETFWVASEILSESNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRGTWEKLPSKYEKHLQDLQDLFDPSRNMAKYRNILSSQSMQPPIIPLFPVVKKDMTFLHEGNDSKVDGLVNFEKLRMIAKEIRHIVRMTSANMDPAMMFRQRSLSQGSTNSNMLDVQGGAHKKRARRSSLLNAKKLYEDAQMARKVKQYLSSLDIDTDEEKFQMISLQWEPAYGTLTKNLTEKKSAKSSEMSPVPLRSGGQTSKVHLHQPHRVSQVLQVPAVNLHPIRKRGQAKDHVLSTSLSQKGLGPTEEVSGKKHTEDTVSVASSLHSSPPASPQSSPRKGYTLIPSAKSDNLSDSSHSEISSRSSIVSNCSVDSMSAALQEERCSSHTLAVPELTAGAFEKTDHPSGIREHSQLGHGWMLSKPSLIKGVAVSSSLSSEEMSHEHVVLEAADSGRGSWTSCSSSSHDNFQSLPNPKSWDFLNTYRHTHLDDPIAEVEPTDCEPCACPKSCSRTCGQCKGSLETSQLRQSWASSSSLSDTYEPNYGTVKRRVLESAPSEAPDGLEPRDTTDPIYKTVTSSTDRGLIVYCVTSPKKGDRYREPPPTPPGYLGISLADLKEGPHPHLKPPDYSVAVQRSKMMFNSLSRLPPAPPSGHALAWVPSKTGSQPHRHSLQPSHPKLADVADADSEADENEQVSAV", "length": 1619, "header": "tr|A0A9J7K0G5-1|A0A9J7H4E5_CRIGR Computationally mapped isoform of Rap guanine nucleotide exchange factor 6 isoform X10 OS=Cricetulus griseus OX=10029 GN=Rapgef6 PE=3 SV=1 CANONICAL=A0A9J7H4E5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K9Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5/entry#A0A9J7K9Z0-1", "sequence": { "sequence": "MAFLVRCYANCLQPWASKLPADLTKMHLTDNPHPQVTHVSSSQSGCSIASDSGSSSLSDIYQATESEVGDVDLTRLPEGPVDSEDEEDEEEEIDRTDPLQGRDLVRECLEKEPADKTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAVILEDGQELDSWYVILNGTVEITHPDGKIENLFMGNSFGIVPTLDKQHMHGVVRTKVDDCQFVCIAQQDYWRILNHVEKNTHKVEEEGEIVMVHEHRELDRSGTRKGHIVIKATPERLIMHLIEEHSIVDPTYIEDFLLTYRTFLESPLDVGIKLLEWFKIDSLRDKVTRIVLLWVNNHFNDFEGDPAMTRFLEEFEKNLEDTKMNGHLRLLNIACAAKAKWRQVVLQKASRESPLHFILNGGSEKGFGVFVEGVEPGSKAADAGLKRGDQIMEVNGQNFENITFVKALEILRNNTHLALTVKTNIFVFKELLSRTEQEKSGIPHIPKIAEKKSNRHSIQDVPGDIEQIPQEKGNKKVKANTVSGGRNKIRKILDKTRFSILPPKLFSDGGLSQSQDDSIVGTRHCRHSLAIMPIPGTLSSSSPDLLQPTTSMLDFSNPSDIPDQVIRVFKADQQSCYIIISKDTTAKEVVCQAIQEFGLTGTSETYSLCEVSVTPEGVIKQRRLPDQFSKLADRIQLNGRYYLKNNMETETLCSDEDAQELLKESQLSMLQLSTIEVATQLSMRDFDLFRNIEPTEYIDDLFKLDSKTGNTHLKQFEDIVNQETFWVASEILSESNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRGTWEKLPSKYEKHLQDLQDLFDPSRNMAKYRNILSSQSMQPPIIPLFPVVKKDMTFLHEGNDSKVDGLVNFEKLRMIAKEIRHIVRMTSANMDPAMMFRQRKKRWRSLGSLSQGSTNSNMLDVQGGAHKKRARRSSLLNAKKLYEDAQMARKVKQYLSSLDIDTDEEKFQMISLQWEPAYGTLTKNLTEKKSAKSSEMSPVPLRSGGQTSKVHLHQPHRVSQVLQVPAVNLHPIRKRGQAKDHVLSTSLSQKGLGPTEEVSGKKHTEDTVSVASSLHSSPPASPQSSPRKGYTLIPSAKSDNLSDSSHSEISSRSSIVSNCSVDSMSAALQEERCSSHTLAVPELTAGAFEKTDHPSGIREHSQLGHGWMLSKPSLIKGVAVSSSLSSEEMSHEHVVLEAADSGRGSWTSCSSSSHDNFQSLPNPKSWDFLNTYRHTHLDDPIAEVEPTDCEPCACPKSCSRTCGQCKGSLETSQLRQSWASSSSLSDTYEPNYGTVKRRVLESAPSEAPDGLEPRDTTDPIYKTVTSSTDRGLIVYCVTSPKKGDRYREPPPTPPGYLGISLADLKEGPHPHLKPPDYSVAVQRSKMMFNSLSRLPPAPPSGHALAWVPSKTGSQPHRHSLQPSHPKLADVADADSEADENEQVSAV", "length": 1467, "header": "tr|A0A9J7K9Z0-1|A0A9J7H4E5_CRIGR Computationally mapped isoform of Rap guanine nucleotide exchange factor 6 isoform X10 OS=Cricetulus griseus OX=10029 GN=Rapgef6 PE=3 SV=1 CANONICAL=A0A9J7H4E5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5/entry#A0A9J7KBF3-1", "sequence": { "sequence": "MNSPVDPGARQALRKKPPERTPEDLNTIYSYLHGMEILSNLREHQLRLMSARARYERYNGNQMLFCSETIARCWYILLSGSVLVKDSMVLPPCRPQIDYFLASTPPGFGKQFGGKRGCDCLVLEPSEMIVVENSKDNEDSILQREIPARQSRRRFRKINYKGERQTITDGVDVNNYLSATESEVGDVDLTRLPEGPVDSEDEEDEEEEIDRTDPLQGRDLVRECLEKEPADKTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAVILEDGQELDSWYVILNGTVEITHPDGKIENLFMGNSFGIVPTLDKQHMHGVVRTKVDDCQFVCIAQQDYWRILNHVEKNTHKVEEEGEIVMVHEHRELDRSGTRKGHIVIKATPERLIMHLIEEHSIVDPTYIEDFLLTYRTFLESPLDVGIKLLEWFKIDSLRDKVTRIVLLWVNNHFNDFEGDPAMTRFLEEFEKNLEDTKMNGHLRLLNIACAAKAKWRQVVLQKASRESPLHFILNGGSEKGFGVFVEGVEPGSKAADAGLKRGDQIMEVNGQNFENITFVKALEILRNNTHLALTVKTNIFVFKELLSRTEQEKSGIPHIPKIAEKKSNRHSIQDVPGDIEQIPQEKGNKKVKANTVSGGRNKIRKILDKTRFSILPPKLFSDGGLSQSQDDSIVGTRHCRHSLAIMPIPGTLSSSSPDLLQPTTSMLDFSNPSDIPDQVIRVFKADQQSCYIIISKDTTAKEVVCQAIQEFGLTGTSETYSLCEVSVTPEGVIKQRRLPDQFSKLADRIQLNGRYYLKNNMETETLCSDEDAQELLKESQLSMLQLSTIEVATQLSMRDFDLFRNIEPTEYIDDLFKLDSKTGNTHLKQFEDIVNQETFWVASEILSESNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRGTWEKLPSKYEKHLQDLQDLFDPSRNMAKYRNILSSQSMQPPIIPLFPVVKKDMTFLHEGNDSKVDGLVNFEKLRMIAKEIRHIVRMTSANMDPAMMFRQRKKRWRSLGSLSQGSTNSNMLDVQGGAHKKRARRSSLLNAKKLYEDAQMARKVKQYLSSLDIDTDEEKFQMISLQWEPAYGTLTKNLTEKKSAKSSEMSPVPLRSGGQTSKVHLHQPHRVSQVLQVPAVNLHPIRKRGQAKDHVLSTSLSQKGLGPTEEVSGKKHTEDTVSVASSLHSSPPASPQSSPRKGYTLIPSAKSDNLSDSSHSEISSRSSIVSNCSVDSMSAALQEERCSSHTLAVPELTAGAFEKTDHPSGIREHSQLGHGWMLSKPSLIKGVAVSSSLSSEEMSHEHVVLEAADSGRGSWTSCSSSSHDNFQSLPNPKSWDFLNTYRHTHLDDPIAEVEPTDCEPCACPKSCSRTCGQCKGSLETSQLRQSWASSSSLSDTYEPNYGTVKRRVLESAPSEAPDGLEPRDTTDPIYKTVTSSTDRGLIVYCVTSPKKGDRYREPPPTPPGYLGISLADLKEGPHPHLKPPDYSVAVQRSKMMFNSLSRLPPAPPSGHALAWVPSKTGSQPHRHSLQPSHPKLADVADADSEADENEQVSAV", "length": 1583, "header": "tr|A0A9J7KBF3-1|A0A9J7H4E5_CRIGR Computationally mapped isoform of Rap guanine nucleotide exchange factor 6 isoform X10 OS=Cricetulus griseus OX=10029 GN=Rapgef6 PE=3 SV=1 CANONICAL=A0A9J7H4E5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1533, "start_aa": "Thr", "end_pos": 1533, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1533", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JPZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPZ5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JPZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPZ5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763755", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763755", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5" } ], "pmid": "" }, { "name": "GTP-dependent protein binding", "id": "GO:0030742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030742", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5" } ], "pmid": "" }, { "name": "phosphatidic acid binding", "id": "GO:0070300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070300", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302907", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302907" } ] }, { "annotation": "Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JZY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZY1#function" }, { "database": "UniProtKB", "id": "ARBA00054938", "url": "https://www.uniprot.org/uniprotkb/ARBA00054938#function" }, { "database": "UniProtKB", "id": "A0A9J7H372", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H372#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H372", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H372" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100772712", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H372", "locus": {} } ], "crossref": [ { "id": "A0A9J7H372", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H372", "database": "AlphaFoldDB", "categories": [] }, { "id": "100772712", "url": "https://www.ncbi.nlm.nih.gov/gene/100772712", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772712", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772712", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H372", "url": "https://www.orthodb.org/?gene=A0A9J7H372", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23233", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23233", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23233:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23233:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302907", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302907", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2ML31", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2ML31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2ML63", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2ML63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H372", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H372", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H372-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H372-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAV8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRRKQAKPQHINSEEGQGEQPLQQPSPDLAEAPAAEEPGELGAPVNSPGNGDEVTEDMALVKRPRREETHICEKCCAEFFSLSEFVEHKKSCTKNPPVLIMNDSEGPVPSEDFPRAVLSHQPDSPSNKDSHQDNSGGSGSSKEKLGMDSILYLKTEASLPPTSQNISYLPKGKVANTNVTLQALRGTKVAVNQRSVDAPAAPMSVAHTIPWVLEQILCLQQQQLQQIQLTEQIRVQVNLWAAHALHSGMAGADTLKALSNHVSQQVSISQQVSAAVALLNQKSSNPALSLDALKQTKLPHANAPSTTGSLSSGFTPFTLKPDGTRVLPNFMSRLPSALLPQTPGSVLLQSPFASAALDPSKKGKGKPPNVSATALDVKVKDETVLGKHKCKYCSKVFGTDSSLQIHLRSHTGERPYVCSVCGHRFTTKGNLKVHFYRHPQVKANPQLFAEFQDKAAAGTGSPYAPSAPIPVDESSLSVETKPAHVTGTPSTGLPQKLTSGPNPKDLMGGYLPNDTQPGPSPESEVGLPLLGGGLANNPPRVGGLQGSGTPESGSETLKLQQLVENIDKATADPNECFICHRVLSCQSSLKMHYRTHTGERPYQCKICGRAFSTKGNLKTHLGVHQTNTAVKTQHSCPICQKKFTNAVMLQQHIRMHMGGQIPNTPLPESPCDFTGPEPMVVSENGSANAVCQEDSVERMEADDICSRDVPGGSSKVSQSVPGTHLVSPILDFSVMASLDTQGKGAPPPLGLQWQSSRENGSVERDNCLVNDLSSLMGDQECRSQSLDGEESMCLQAVSPANSQAESVKSRSPDAEGIKAEGVESCRIDMEARTGIPSTYSHAQPTYVKVEVPGTFVGPSSMSSSTTPLVAAQPRRQAKQHCCTRCGKNFSSASAVQIHERTHTGEKPFVCNVCGRAFTTKGNLKVHYMTHGANNNAARRGRKLAMENPMAILSAEGKRVSEAFPKELLSPTVSVDPTTWNQYTSVLNGGLAMKTNEISVIQSGGIPTLPMSLGASSVVSNATLSKLESSQSAVSGNMEKPAVPDGVAKHQFPHFLEENKIAVS", "length": 1064, "header": "tr|A0A9J7H372-1|A0A9J7H372_CRIGR Isoform 1 of Sal-like protein 4 OS=Cricetulus griseus OX=10029 GN=LOC100772712 PE=3 SV=1 CANONICAL=A0A9J7H372-1" }, "isoforms": [ { "isoform_ac": "A0A8C2ML31-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H372/entry#A0A8C2ML31-1", "sequence": { "sequence": "MSRRKQAKPQHINSEEGQGEQPLQQPSPDLAEAPAAEEPGAPVNSPGNGDEVTEDMALVKRPRREETHICEKCCAEFFSLSEFVEHKKSCTKNPPVLIMNDSEGPVPSEDFPRAVLSHQPDSPSNKDSHQDNSGGSGSSKEKLGMDSILYLKTEASLPPTSQNISYLPKGKVANTNVTLQALRGTKVAVNQRSVDAPAAPMSVAHTIPWVLEQILCLQQQQLQQIQLTEQIRVQVNLWAAHALHSGMAGADTLKALSNHVSQQVSISQQVSAAVALLNQKSSNPALSLDALKQTKLPHANAPSTTGSLSSGFTPFTLKPDGTRVLPNFMSRLPSALLPQTPGSVLLQSPFASAALDPSKKGKGKPPNVSATALDVKVKDETVLARTGIPSTYSHAQPTYVKVEVPGTFVGPSSMSSSTTPLVAAQPRRQAKQHCCTRCGKNFSSASAVQIHERTHTGEKPFVCNVCGRAFTTKGNLKVHYMTHGANNNAARRGRKLAMENPMAILSAEGKRVSEAFPKELLSPTVSVDPTTWNQYTSVLNGGLAMKTNEISVIQSGGIPTLPMSLGASSVVSNATLSKLESSQSAVSGNMEKPAVPDGVAKHQFPHFLEENKIAVS", "length": 616, "header": "tr|A0A8C2ML31-1|A0A9J7H372_CRIGR Computationally mapped isoform of Sal-like protein 4 OS=Cricetulus griseus OX=10029 GN=LOC100772712 PE=3 SV=1 CANONICAL=A0A9J7H372-1" }, "locus": {} }, { "isoform_ac": "A0A8C2ML63-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H372/entry#A0A8C2ML63-1", "sequence": { "sequence": "MSRRKQAKPQHINSEEGQGEQPLQQPSPDLAEAPAAEEPARTGIPSTYSHAQPTYVKVEVPGTFVGPSSMSSSTTPLVAAQPRRQAKQHCCTRCGKNFSSASAVQIHERTHTGEKPFVCNVCGRAFTTKGNLKVHYMTHGANNNAARRGRKLAMENPMAILSAEGKRVSEAFPKELLSPTVSVDPTTWNQYTSVLNGGLAMKTNEISVIQSGGIPTLPMSLGASSVVSNATLSKLESSQSAVSGNMEKPAVPDGVAKHQFPHFLEENKIAVS", "length": 272, "header": "tr|A0A8C2ML63-1|A0A9J7H372_CRIGR Computationally mapped isoform of Sal-like protein 4 OS=Cricetulus griseus OX=10029 GN=LOC100772712 PE=3 SV=1 CANONICAL=A0A9J7H372-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H372-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H372/entry#A0A9J7H372-1", "sequence": { "sequence": "MSRRKQAKPQHINSEEGQGEQPLQQPSPDLAEAPAAEEPGELGAPVNSPGNGDEVTEDMALVKRPRREETHICEKCCAEFFSLSEFVEHKKSCTKNPPVLIMNDSEGPVPSEDFPRAVLSHQPDSPSNKDSHQDNSGGSGSSKEKLGMDSILYLKTEASLPPTSQNISYLPKGKVANTNVTLQALRGTKVAVNQRSVDAPAAPMSVAHTIPWVLEQILCLQQQQLQQIQLTEQIRVQVNLWAAHALHSGMAGADTLKALSNHVSQQVSISQQVSAAVALLNQKSSNPALSLDALKQTKLPHANAPSTTGSLSSGFTPFTLKPDGTRVLPNFMSRLPSALLPQTPGSVLLQSPFASAALDPSKKGKGKPPNVSATALDVKVKDETVLGKHKCKYCSKVFGTDSSLQIHLRSHTGERPYVCSVCGHRFTTKGNLKVHFYRHPQVKANPQLFAEFQDKAAAGTGSPYAPSAPIPVDESSLSVETKPAHVTGTPSTGLPQKLTSGPNPKDLMGGYLPNDTQPGPSPESEVGLPLLGGGLANNPPRVGGLQGSGTPESGSETLKLQQLVENIDKATADPNECFICHRVLSCQSSLKMHYRTHTGERPYQCKICGRAFSTKGNLKTHLGVHQTNTAVKTQHSCPICQKKFTNAVMLQQHIRMHMGGQIPNTPLPESPCDFTGPEPMVVSENGSANAVCQEDSVERMEADDICSRDVPGGSSKVSQSVPGTHLVSPILDFSVMASLDTQGKGAPPPLGLQWQSSRENGSVERDNCLVNDLSSLMGDQECRSQSLDGEESMCLQAVSPANSQAESVKSRSPDAEGIKAEGVESCRIDMEARTGIPSTYSHAQPTYVKVEVPGTFVGPSSMSSSTTPLVAAQPRRQAKQHCCTRCGKNFSSASAVQIHERTHTGEKPFVCNVCGRAFTTKGNLKVHYMTHGANNNAARRGRKLAMENPMAILSAEGKRVSEAFPKELLSPTVSVDPTTWNQYTSVLNGGLAMKTNEISVIQSGGIPTLPMSLGASSVVSNATLSKLESSQSAVSGNMEKPAVPDGVAKHQFPHFLEENKIAVS", "length": 1064, "header": "tr|A0A9J7H372-1|A0A9J7H372_CRIGR Isoform 1 of Sal-like protein 4 OS=Cricetulus griseus OX=10029 GN=LOC100772712 PE=3 SV=1 CANONICAL=A0A9J7H372-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JZY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H372/entry#A0A9J7JZY1-1", "sequence": { "sequence": "MSRRKQAKPQHINSEEGQGEQPLQQPSPDLAEAPAAEEPGAPVNSPGNGDEVTEDMALVKRPRREETHICEKCCAEFFSLSEFVEHKKSCTKNPPVLIMNDSEGPVPSEDFPRAVLSHQPDSPSNKDSHQDNSGGSGSSKEKLGMDSILYLKTEASLPPTSQNISYLPKGKVANTNVTLQALRGTKVAVNQRSVDAPAAPMSVAHTIPWVLEQILCLQQQQLQQIQLTEQIRVQVNLWAAHALHSGMAGADTLKALSNHVSQQVSISQQVSAAVALLNQKSSNPALSLDALKQTKLPHANAPSTTGSLSSGFTPFTLKPDGTRVLPNFMSRLPSALLPQTPGSVLLQSPFASAALDPSKKGKGKPPNVSATALDVKVKDETVLGKHKCKYCSKVFGTDSSLQIHLRSHTGERPYVCSVCGHRFTTKGNLKVHFYRHPQVKANPQLFAEFQDKAAAGTGSPYAPSAPIPVDESSLSVETKPAHVTGTPSTGLPQKLTSGPNPKDLMGGYLPNDTQPGPSPESEVGLPLLGGGLANNPPRVGGLQGSGTPESGSETLKLQQLVENIDKATADPNECFICHRVLSCQSSLKMHYRTHTGERPYQCKICGRAFSTKGNLKTHLGVHQTNTAVKTQHSCPICQKKFTNAVMLQQHIRMHMGGQIPNTPLPESPCDFTGPEPMVVSENGSANAVCQEDSVERMEADDICSRDVPGGSSKVSQSVPGTHLVSPILDFSVMASLDTQGKGAPPPLGLQWQSSRENGSVERDNCLVNDLSSLMGDQECRSQSLDGEESMCLQAVSPANSQAESVKSRSPDGIKAEGVESCRIDMEARTGIPSTYSHAQPTYVKVEVPGTFVGPSSMSSSTTPLVAAQPRRQAKQHCCTRCGKNFSSASAVQIHERTHTGEKPFVCNVCGRAFTTKGNLKVHYMTHGANNNAARRGRKLAMENPMAILSAEGKRVSEAFPKELLSPTVSVDPTTWNQYTSVLNGGLAMKTNEISVIQSGGIPTLPMSLGASSVVSNATLSKLESSQSAVSGNMEKPAVPDGVAKHQFPHFLEENKIAVS", "length": 1059, "header": "tr|A0A9J7JZY1-1|A0A9J7H372_CRIGR Computationally mapped isoform of Sal-like protein 4 OS=Cricetulus griseus OX=10029 GN=LOC100772712 PE=3 SV=1 CANONICAL=A0A9J7H372-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H372/entry#A0A9J7KAV8-1", "sequence": { "sequence": "MSRRKQAKPQHINSEEGQGEQPLQQPSPDLAEAPAAEEPGELGAPVNSPGNGDEVTEDMALVKRPRREETHICEKCCAEFFSLSEFVEHKKSCTKNPPVLIMNDSEGPVPSEDFPRAVLSHQPDSPSNKDSHQDNSGGSGSSKEKLGMDSILYLKTEASLPPTSQNISYLPKGKVANTNVTLQALRGTKVAVNQRSVDAPAAPMSVAHTIPWVLEQILCLQQQQLQQIQLTEQIRVQVNLWAAHALHSGMAGADTLKALSNHVSQQVSISQQVSAAVALLNQKSSNPALSLDALKQTKLPHANAPSTTGSLSSGFTPFTLKPDGTRVLPNFMSRLPSALLPQTPGSVLLQSPFASAALDPSKKGKGKPPNVSATALDVKVKDETVLGKHKSRTGIPSTYSHAQPTYVKVEVPGTFVGPSSMSSSTTPLVAAQPRRQAKQHCCTRCGKNFSSASAVQIHERTHTGEKPFVCNVCGRAFTTKGNLKVHYMTHGANNNAARRGRKLAMENPMAILSAEGKRVSEAFPKELLSPTVSVDPTTWNQYTSVLNGGLAMKTNEISVIQSGGIPTLPMSLGASSVVSNATLSKLESSQSAVSGNMEKPAVPDGVAKHQFPHFLEENKIAVS", "length": 623, "header": "tr|A0A9J7KAV8-1|A0A9J7H372_CRIGR Computationally mapped isoform of Sal-like protein 4 OS=Cricetulus griseus OX=10029 GN=LOC100772712 PE=3 SV=1 CANONICAL=A0A9J7H372-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JZY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZY1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JZY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZY1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772712", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772712", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H372", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H372" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H372", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H372" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H372", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H372" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H372", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H372" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H372", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H372" } ], "pmid": "" }, { "name": "DNA-binding 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This record is derived from a genomic sequence (NW_003613667.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497908" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY23", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY23" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sidt1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY23", "locus": {} } ], "crossref": [ { "id": "100767535", "url": "https://www.ncbi.nlm.nih.gov/gene/100767535", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767535", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767535", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SDTDMGI", "url": "https://omabrowser.org/oma/group/SDTDMGI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MQ01", "url": "https://www.orthodb.org/?gene=A0A8C2MQ01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MY23", "url": "https://www.orthodb.org/?gene=A0A8C2MY23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12185", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12185", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12185:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12185:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13965", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13965", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003497908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497908", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MQ01", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MQ01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MY23", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MY23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYW5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JY39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JY39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JY39-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JY39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5H3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5H3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGCPPLALLCALPWLLWAEVPGHQAEPLGQTAELLRDSRDPARGADFDRVYSGVVSLSTENIYSFNLTSHPGQVTAVRVHVNSSSENLDYPVLVVVRQQKEVLSWQVPLLFQGLYQRSYNYQEVSRTLCPSKATNETGPLQQLIFVDVASMAPHGAHYKLLVTKIKHFQLRTNVAFHFTASPSQPQYFLYEFPEDVDSVIIKVVSEKAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSMTKKAAITLQKKDFPDKQFFVVFVIKPEDYACGGSFSIQENENQTWNLQRSKNLKVTIVPSIKESVYVKSSLFSVSIFLSFYLGCLLVMLIHHVRFQRKSISGSFGSSDGSGNMAVSHPIAASTPEGSNYGAIDESSSSPGRQMSSSDGGQPCHSDTDSSVEESDFDTMPDIESDKNVIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVMQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNMGHVLLGFLFLLIVLRRDLLHRRALEAKDIFAMEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVITLTVLGVVFGKNDVWFWVIFSAIHILASLALSTQIYYMGRVKIDVSDTDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLIVGNLVNWSFAFFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLLLPLFCIVATAVVWAAALYFFFQNLSSWEGTPAESREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF", "length": 832, "header": "tr|A0A8C2MY23-1|A0A8C2MY23_CRIGR Isoform 1 of SID1 transmembrane family member 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Sidt1 PE=3 SV=1 CANONICAL=A0A8C2MY23-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MQ01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY23/entry#A0A8C2MQ01-1", "sequence": { "sequence": "MLGCPPLALLCALPWLLWAEVPGHQAEPLGQTAELLRDSRDPARGADFDRVYSGVVSLSTENIYSFNLTSHPGQVTAVRVHVNSSSENLDYPVLVVVRQQKEVLSWQVPLLFQGLYQRSYNYQEVSRTLCPSKATNETGPLQQLIFVDVASMAPHGAHYKLLVTKIKHFQLRTNVAFHFTASPSQPQYFLYEFPEDVDSVIIKVVSEKAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSMTKKAAITLQKKDFPDKQFFVVFVIKPEDYACGGSFSIQENENQTWNLQRSKNLKVTIVPSIKESVYVKSSLFSVSIFLSFYLGCLLVMLIHHVRFQRKSISGSFGSSDGSGNMAVSHPIAASTPEGSNYGAIDESSSSPGRQMSSSDGGQPCHSDTDSSVEESDFDTMPDIESDKNVIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVMQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNMGHVLLGFLFLLIVLRRDLLHRRALEAKDIFAMEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVITLTVLGVVFGKNDVWFWVIFSAIHILASLALSTQIYYMGRVKIDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLIVGNLVNWSFAFFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLLLPLFCIVATAVVWAAALYFFFQNLSSWEGTPAESREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF", "length": 827, "header": "tr|A0A8C2MQ01-1|A0A8C2MY23_CRIGR Computationally mapped isoform of SID1 transmembrane family member 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Sidt1 PE=3 SV=1 CANONICAL=A0A8C2MY23-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MY23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY23/entry#A0A8C2MY23-1", "sequence": { "sequence": "MLGCPPLALLCALPWLLWAEVPGHQAEPLGQTAELLRDSRDPARGADFDRVYSGVVSLSTENIYSFNLTSHPGQVTAVRVHVNSSSENLDYPVLVVVRQQKEVLSWQVPLLFQGLYQRSYNYQEVSRTLCPSKATNETGPLQQLIFVDVASMAPHGAHYKLLVTKIKHFQLRTNVAFHFTASPSQPQYFLYEFPEDVDSVIIKVVSEKAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSMTKKAAITLQKKDFPDKQFFVVFVIKPEDYACGGSFSIQENENQTWNLQRSKNLKVTIVPSIKESVYVKSSLFSVSIFLSFYLGCLLVMLIHHVRFQRKSISGSFGSSDGSGNMAVSHPIAASTPEGSNYGAIDESSSSPGRQMSSSDGGQPCHSDTDSSVEESDFDTMPDIESDKNVIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVMQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNMGHVLLGFLFLLIVLRRDLLHRRALEAKDIFAMEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVITLTVLGVVFGKNDVWFWVIFSAIHILASLALSTQIYYMGRVKIDVSDTDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLIVGNLVNWSFAFFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLLLPLFCIVATAVVWAAALYFFFQNLSSWEGTPAESREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF", "length": 832, "header": "tr|A0A8C2MY23-1|A0A8C2MY23_CRIGR Isoform 1 of SID1 transmembrane family member 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Sidt1 PE=3 SV=1 CANONICAL=A0A8C2MY23-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GYW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY23/entry#A0A9J7GYW5-1", "sequence": { "sequence": "MLGCPPLALLCALPWLLWAEVPGHQAEPLGQTAELLRDSRDPARGADFDRVYSGVVSLSTENIYSFNLTSHPGQVTAVRVHVNSSSENLDYPVLVVVRQQKEVLSWQVPLLFQGLYQRSYNYQEVSRTLCPSKATNETGPLQQLIFVDVASMAPHGAHYKLLVTKIKHFQLRTNVAFHFTASPSQPQKKDFPDKQFFVVFVIKPEDYACGGSFSIQENENQTWNLQRSKNLKVTIVPSIKESVYVKSSLFSVSIFLSFYLGCLLVMLIHHVRFQRKSISGSFGSSDGSGNMAVSHPIAASTPEGSNYGAIDESSSSPGRQMSSSDGGQPCHSDTDSSVEESDFDTMPDIESDKNVIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVMQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNMGHVLLGFLFLLIVLRRDLLHRRALEAKDIFAMEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVITLTVLGVVFGKNDVWFWVIFSAIHILASLALSTQIYYMGRVKIDVSDTDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLIVGNLVNWSFAFFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLLLPLFCIVATAVVWAAALYFFFQNLSSWEGTPAESREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF", "length": 770, "header": "tr|A0A9J7GYW5-1|A0A9J7GYW5_CRIGR Computationally mapped isoform of SID1 transmembrane family member 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Sidt1 PE=3 SV=1 CANONICAL=A0A8C2MY23-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JY39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY23/entry#A0A9J7JY39-1", "sequence": { "sequence": "MLGCPPLALLCALPWLLWAEVPGHQAEPLGQTAELLRDSRDPARGADFDRVYSGVVSLSTENIYSFNLTSHPGQVTAVRVHVNSSSENLDYPVLVVVRQQKEVLSWQVPLLFQGLYQRSYNYQEVSRTLCPSKATNETGPLQQLIFVDVASMAPHGAHYKLLVTKIKHFQLRTNVAFHFTASPSQPQYFLYEFPEDVDSVIIKVVSEKAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSMTKKAAITLQKDFPDKQFFVVFVIKPEDYACGGSFSIQENENQTWNLQRSKNLKVTIVPSIKESVYVKSSLFSVSIFLSFYLGCLLVMLIHHVRFQRKSISGSFGSSDGSGNMAVSHPIAASTPEGSNYGAIDESSSSPGRQMSSSDGGQPCHSDTDSSVEESDFDTMPDIESDKNVIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVMQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNMGHVLLGFLFLLIVLRRDLLHRRALEAKDIFAMEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVITLTVLGVVFGKNDVWFWVIFSAIHILASLALSTQIYYMGRVKIDVSDTDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLIVGNLVNWSFAFFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLLLPLFCIVATAVVWAAALYFFFQNLSSWEGTPAESREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF", "length": 831, "header": "tr|A0A9J7JY39-1|A0A8C2MY23_CRIGR Computationally mapped isoform of SID1 transmembrane family member 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Sidt1 PE=3 SV=1 CANONICAL=A0A8C2MY23-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K5H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY23/entry#A0A9J7K5H3-1", "sequence": { "sequence": "MLGCPPLALLCALPWLLWAEVPGHQAEPLGQTAELLRDSRDPARGADFDRVYSGVVSLSTENIYSFNLTSHPGQVTAVRVHVNSSSENLDYPVLVVVRQQKEVLSWQVPLLFQGLYQRSYNYQEVSRTLCPSKATNETGPLQQLIFVDVASMAPHGAHYKLLVTKIKHFQLRTNVAFHFTASPSQPQYFLYEFPEDVDSVIIKVVSEKAYPCSVVSVQNIMKKDFPDKQFFVVFVIKPEDYACGGSFSIQENENQTWNLQRSKNLKVTIVPSIKESVYVKSSLFSVSIFLSFYLGCLLVMLIHHVRFQRKSISGSFGSSDGSGNMAVSHPIAASTPEGSNYGAIDESSSSPGRQMSSSDGGQPCHSDTDSSVEESDFDTMPDIESDKNVIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVMQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNMGHVLLGFLFLLIVLRRDLLHRRALEAKDIFAMEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVITLTVLGVVFGKNDVWFWVIFSAIHILASLALSTQIYYMGRVKIDVSDTDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLIVGNLVNWSFAFFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLLLPLFCIVATAVVWAAALYFFFQNLSSWEGTPAESREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF", "length": 804, "header": "tr|A0A9J7K5H3-1|A0A8C2MY23_CRIGR Computationally mapped isoform of SID1 transmembrane family member 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Sidt1 PE=3 SV=1 CANONICAL=A0A8C2MY23-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JY39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JY39" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JY39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JY39" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767535", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767535", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q3AP82-1", "protein_name": "SID1 transmembrane family member 1", "gene_name": "SIDT1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGGAAAAPGALLCALLWAVTAAAPGGGPAPGAFGRVYRGAVNISAERLYAFAYSSEPGQVDAVRVYVNSSSENLQYPVLFVVRQQKGVLSWQVPLIFRGLYQRTYNYQEVSRTLCPSEPAPETGPSDQIIFVDVASMAPFNIAYELLVTRLESFQLETNKPFNFTASPSQPQYFLYKFPQDVDSVIIKVVSDAVYPCSVVSVQDIVCPVYDLDHNVEFNGVYQSMTKQAAITVQRKDFPGEQFFVVFVIKPEDYACGGSVPSSIHGNVNRTWNLQRTKNLQVTIVPSIKKSVYIQAMLFSFLSFLSFYVGSVVVAFVHYIRVRRKASAERLSPESGSGIMTSSHPITASTPEGSSYGAIDESSSSGGRQLSSPERGPPAGSDTDSSVEEESDFDTMPEIESDKNVIRTKVFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNVGHMLLGFLFLLIVLRRDILHRRAMEMKDVYTLDYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVICLAVLGVVFGKNDVWFWVIFSLIHVLASLALSTQIYYMGRFKMDGPDSDLGIFRRAAMVLYTDCIQQCSRPMYMDRMVLLIVGNLVNWSFAIFGLVYRPRDFASYILGIFICNLLLYLAFYIIMKIRSSEKLLPIPLFCIVATAVVWAAALYFFFQTLSSWEETPAESREKNRSCILLGFFDDHDVWHFLSAAALFFSFLVLLTLDDDLDTVRRDKIPVF", "length": 821 }, "evidence": [ { "id": "A0A8C2MY23", "url": "https://omabrowser.org/oma/group/A0A8C2MY23/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9RWZ1-1", "protein_name": "SID1 transmembrane family member 1", "gene_name": "SIDT1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGCTRLALLCALPWLLPLVAPGRPAPPPALRRDPRNPARGAQFDRIYSGVVSLPTENIYSFNYTSQPGQVTAVRVYVNSSSENLDYPVLVVVRQQKEVLSWQVPLLFQGLYQRSYNYQEVSRTLCPSEATNETGPLEQLIFVDVASMAPLGAQYKLLVTKLKHFQLQTNVAFHFTASPSQPQYFLYKFPEDVDSVIIKVVSTLAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSMTKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRAKNLQVTIVPSSKGSVYVKAILLSFLIFFSFYLGCLFVAFIHFIRFRRKSTDGSFGSSDGSGNMSVSNPIAASTPEGSNYGAIDESSSSPGRQISSSDGRQPCQSDTDSSVEESDFDTMPDIESDKNIIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICFYNFLCAHPLGVLSAFNNILSNLGHVLLGCLFLLIVLHRDILHRRALEAKDIFAMEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASAYAAYASFALVITLTVLGVVFGKNDMWFWVIFSAIHILASLALSTQIYYMGRFKIDVSDTDWGIFRRAAVVFYTDCIQQRSRPLYMDRMVLLIVGNLVNWSFALFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKILLIPLFCIVATAVVWAAALYFFFQNLSSWEGTPAESREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDLVRRDQIPVF", "length": 828 }, "evidence": [ { "id": "A0A8C2MY23", "url": "https://omabrowser.org/oma/group/A0A8C2MY23/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6AXF6-1", "protein_name": "SID1 transmembrane family member 1", "gene_name": "Sidt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLDCLRLALLCALPWLLRAAVPGHQEEPLAKSAELRRDPRDPARGADFDRVYSGVVSLSTENIYSFNHTSHPGQVTAVRVHVNSSSDNLDYPVLVVVRQQKEVLSWQVPLLFQGLYQRSYNYQEVSRTLCPSKATNETGPLEQLIFVDVASMAPHGAHYKLLVTKIKHFQLPTNVAFYFTASPSQPQYFLYKFPEDVDSVIIKVVSEKAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSMTKKAAITLQKKDFPDEQFFVVFVIKPEDYACGGSFSIQENENQTWNLQRSKNLKVTIVPSIKESVYVKSSLFSIFVFLSFYLGCLLVVLVHHVRFQRKSIDGSFGSSDGSGNMAVSHPITASTPEGSNYGAIDESSSSPGRQMSSSDGGQPCHSDTDSSVEESDFDTMPDIESDKNVIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVMQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDLLHRRALEAKDIFAMEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVITLTVLGVVFGKNDVWFWIIFSAIHILSSLALSTQIYYMGRFKIDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLIVGNLVNWSFAFFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLPLPVFCIAATAVVWAAALYFFFQNLSSWEGTPAESREKNRECVLLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF", "length": 827 }, "evidence": [ { "id": "A0A8C2MY23", "url": "https://omabrowser.org/oma/group/A0A8C2MY23/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6Q3F5-1", "protein_name": "SID1 transmembrane family member 1", "gene_name": "Sidt1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLDCPRLALLCALPWLLRAAVPGHRAEPLKRSAELPRNPRDPARGADFDRVYSGVVSLSTENIYSFNHTSHPGQVTAVRVHVNSSSDNLDYPVLVVVRQQKQVLSWQVPLPFQGLYQRSYNYQEVSRTLCPSKATNETGPLEQLIFVDVASMAPHGAHYKLLVTKIKHFQLRTNVAFYFTASPSQPQYFLYKFPEDVDSVIIKVVSEKAYPCSVVSVQNIMCPVYDLDHDVEFNGVYQSMTKQAAITLQKDFPDEQFFVVFVIKPEDYACGGSFSIQENENQTWNLQRSKNLKVTIVPSVKGSVYVKSSLFSVFVFLSFYLGCLLVVFVHHMRFQRKPVDGSFGSGDGSGNMAVSHPITASTPEGSNYGAIDESSSSPGRQMSSSDGGQPCHSDTDSSVEESDFDTMPDIESDKNVIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVMQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDLLHRRALEAKDIFAMEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVITLTVLGVVFGKNDVWFWIIFSAIHVLASLALSTQIYYMGRFKIDVSDTDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLIVGNLVNWSFALFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLPLPVFCIVATAVVWAAALYFFFQNLSSWEGTPAESREKNRECVLLGFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF", "length": 831 }, "evidence": [ { "id": "A0A8C2MY23", "url": "https://omabrowser.org/oma/group/A0A8C2MY23/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NXL6-1", "protein_name": "SID1 transmembrane family member 1", "gene_name": "SIDT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MYE4-1", "uniprot_ac": "A0A8C2MYE4", "uniprot_id": "A0A8C2MYE4_CRIGR", "mass": { "chemical_mass": 52569.0, "monoisotopic_mass": 52569.0 }, "refseq": { "ac": "XP_003496059", "name": "adenylyl cyclase-associated protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496059" }, "gene_names": [ { "name": "Cap2", "type": "recommended", "evidence": [ { "id": "A0A8C2MYE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE4" } ] }, { "name": "Cap2", "type": "synonym", "evidence": [ { "id": "XP_003496059", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496059" } ] } ], "protein_names": [ { "name": "Adenylyl cyclase-associated protein", "type": "recommended", "evidence": [ { "id": "A0A8C2MYE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE4/entry#names_and_taxonomy" } ] }, { "name": "adenylyl cyclase-associated protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003496059", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496059" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613609.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003496059", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496059" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cap2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE4", "locus": {} } ], "crossref": [ { "id": "100766472", "url": "https://www.ncbi.nlm.nih.gov/gene/100766472", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053950", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053950", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766472", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766472", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PISDHIH", "url": "https://omabrowser.org/oma/group/PISDHIH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MYE4", "url": "https://www.orthodb.org/?gene=A0A8C2MYE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10652", "url": 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"tr|A0A8C2MYE4-1|A0A8C2MYE4_CRIGR Isoform 1 of Adenylyl cyclase-associated protein OS=Cricetulus griseus OX=10029 GN=Cap2 PE=3 SV=1 CANONICAL=A0A8C2MYE4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MQD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE4/entry#A0A8C2MQD0-1", "sequence": { "sequence": "MADMLGLVERLECAVNRLEQLSAGPCGPPGDCGEVNGVNGGVAPSVEAFDKLVNSMVAEFLKKSRVLSGDVETHAEMVHSAFQAQRAFLLMASQYQQPQEGPVASTASVFSVFSSGPGLPPPPPPPPPPGPPPLFENEGKNEESSPSRSALFAQLNQGEAITKGLRHVTDDQKIYKNPSLRAQGQTRSPTKTYTPSPTSPKSNSPQKHAPVLELEGKKWRVEYHEDKNDLVISETELKQVAYIFKCEKSTLQIKGKINSITVDNCKKFGLVFDNVVGIVEVINSKDIQIQVIGRVPTISINKTEGCHLYLSEDALDCEIVSAKSSEMNVLIPQGDDYREFPIPEQFKTVWDGSKLVTEPAEIMA", "length": 364, "header": "tr|A0A8C2MQD0-1|A0A8C2MYE4_CRIGR Computationally mapped isoform of Adenylyl cyclase-associated protein OS=Cricetulus griseus OX=10029 GN=Cap2 PE=3 SV=1 CANONICAL=A0A8C2MYE4-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MYE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE4/entry#A0A8C2MYE4-1", "sequence": { "sequence": "MADMLGLVERLECAVNRLEQLSAGPCGPPGDCGEVNGVNGGVAPSVEAFDKLVNSMVAEFLKKSRVLSGDVETHAEMVHSAFQAQRAFLLMASQYQQPQENEVAVLLKPISEKIQEIQTFRERNRGSSMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSQLQAYIKEHHTTGLTWSKTGPVASTASVFSVFSSGPGLPPPPPPPPPPGPPPLFENEGKNEESSPSRSALFAQLNQGEAITKGLRHVTDDQKIYKNPSLRAQGQTRSPTKTYTPSPTSPKSNSPQKHAPVLELEGKKWRVEYHEDKNDLVISETELKQVAYIFKCEKSTLQIKGKINSITVDNCKKFGLVFDNVVGIVEVINSKDIQIQVIGRVPTISINKTEGCHLYLSEDALDCEIVSAKSSEMNVLIPQGDDYREFPIPEQFKTVWDGSKLVTEPAEIMA", "length": 476, "header": "tr|A0A8C2MYE4-1|A0A8C2MYE4_CRIGR Isoform 1 of Adenylyl cyclase-associated protein OS=Cricetulus griseus OX=10029 GN=Cap2 PE=3 SV=1 CANONICAL=A0A8C2MYE4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 310, "start_aa": "Thr", "end_pos": 310, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr310", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MQD0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQD0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MQD0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQD0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766472", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766472", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IXA9-1", "protein_name": "Adenylyl cyclase-associated protein", "gene_name": "cap2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEALVGRLERAVVRLEAVAVKLQSCPGGLINGDISAVINGGESQSMEAFDRLLSGSVSEYVQSSAAIGGDVAKHAEMVNNALQVQRTLLKMAMTHQEPAKTELADLLRPLSDQIQAVQNFREKNRGSSLFNHLSAVSESIPALGWVAVCQKPGPYVKEMNDAAMFYTNRVLKDFKDTDARHVEWVRSYLSIWTDLQTFIREHHCTGLIWSKTGPKAPPSLLSAPLLPPPPPPPPPMMIDSCSSPADASSVQHAALFAQLNQGEEITKGLKHVCDEQKTHKNPNLRSQSGKTHHDSPSKTQSSSSSNPARKHPPVLELEGKKWRVEYQDQCAELLIEDTELRQVVYVFSCSGSTLQVKGKVNSIIVDNCKKLGLVFDNVVGIVEIINSRDIQLQVMGKVPTISINKTEGCHVYLSKDSLDCEIVSAKSSEMNILVPEGEDDYREFPVPEQFKTVWDGSSLVTEPTKIAG", "length": 468 }, "evidence": [ { "id": "A0A8C2MYE4", "url": "https://omabrowser.org/oma/group/A0A8C2MYE4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AAA9T3I1-1", "protein_name": "Adenylyl cyclase-associated protein", "gene_name": "CAP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEMQGLMERLERAVGRLELLSAGSHRPPGDCGEINGVNGGVAPSVEAFDKLMNSMVAEFLKKSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPQENDVAALLKPISEKIQEIQTFRERNRGSTMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTASALSVLSLGPGLPPPPPPPPPPGPPLLFESEGIKEPSSPSRSALFAQLNQGEAITKGLRHVTDDQKTYKNPNLRAHGGQSPSPTKSHTPGPKSPQSHPSKKHTPVLELEGKKWRVEYQEDRNDLVISETALRQVAYIFKCGKSTLQIKGKINSIIIDNCKKFGLVFDNVVGIVEVINSKDIQMQVMGKVPTISINKTEGCHIYLSEDALDCEIVSAKSSEMNILIPQDGDYREFPVPEQFKTAWDGAKLITEPTEIMVSERPPKPLT", "length": 486 }, "evidence": [ { "id": "A0A8C2MYE4", "url": "https://omabrowser.org/oma/group/A0A8C2MYE4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BZ03-1", "protein_name": "Adenylyl cyclase-associated protein", "gene_name": "CAP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAENHGLMERLEKAVTRLESLFSDSQRSGGMECDAMNGVNGSIAPYVEAFDRLLNGSVAEFLRYSKILEGDVKTHAEMVRAAFQAQRSFLVLASQCQEPQENEVAVLLKPISEKIQEIQNFRERNRGSKMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDTRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASPTSMRSVLTSGSCLSSPPPPPPPPPGPPPIFDTETPPKDEGTASRSALFAQLNQGEAITKGLRHVSDDQKTHKNPSLRAQGPPARSPTKSHTPSPTSPKNSPQQSHAPVLELEGKKWRVEYQEDKNDLVITNTELKQVAYIFKCNKSTLQIKGKINSITIDNCKKFGLVFDNVVGIVEVINSRDIQIQVMGKVPTISINKTEGCHIYLSEESLDCEIVSAKSSEMNILIPQDGDYKEFPVPEQFKTAWDGSKLVTEPAEIVG", "length": 480 }, "evidence": [ { "id": "A0A8C2MYE4", "url": "https://omabrowser.org/oma/group/A0A8C2MYE4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RUJ0-1", "protein_name": "Adenylyl cyclase-associated protein", "gene_name": "CAP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEMQGLMERLERAVGRLELLSAGSHQPPGDCGGINGVNGGVAPSVEAFDKLMNGMVAEFLKKSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPQENDVAALLKPISEKIQEIQTFRERNRGSKMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTASALSVLSLGPGLPPPPPPPPPPGPPPLFESEGRREEPSPSRSALFAQLNQGEAITRGLRHVTDDQKTYKNPSLRAPGGQTPSPTKSHSPGPKSPHSHPPKKHAPMLELEGKKWRIEYQEDRNDLVISETELRQVAYIFKCNKSTLQIKGKINSIIVDNCKKFGLVFDNAVGIVEVINSKDIQMQVMGKVPTISINKTEGCHIYLSEDALDCDIVSAKSSEMNILIPRDGDYREFPVPEQFKTAWDGSKLVTEPTEIMVSERPPKPLN", "length": 486 }, "evidence": [ { "id": "A0A8C2MYE4", "url": "https://omabrowser.org/oma/group/A0A8C2MYE4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P40123-1", "protein_name": "Adenylyl cyclase-associated protein 2", "gene_name": "CAP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANMQGLVERLERAVSRLESLSAESHRPPGNCGEVNGVIAGVAPSVEAFDKLMDSMVAEFLKNSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPHENDVAALLKPISEKIQEIQTFRERNRGSNMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTVSAFSVLSSGPGLPPPPPPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDDQKTYKNPSLRAQGGQTQSPTKSHTPSPTSPKSYPSQKHAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCEKSTIQIKGKVNSIIIDNCKKLGLVFDNVVGIVEVINSQDIQIQVMGRVPTISINKTEGCHIYLSEDALDCEIVSAKSSEMNILIPQDGDYREFPIPEQFKTAWDGSKLITEPAEIMA", "length": 477 }, "evidence": [ { "id": "A0A8C2MYE4", "url": "https://omabrowser.org/oma/group/A0A8C2MYE4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P52481-1", "protein_name": "Adenylyl cyclase-associated protein 2", "gene_name": "Cap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADMLGLMQRLEFAVSRLERLSSGLHEPPGGCGEVNSLSRGIVAPSVEAFDKLINSMVAEFLKNSRVLAGDVETHAEMVHGAFQAQRAFLLMVSQHQQPQENEVAVLLKPISEKIQEIQTFRERNRGSDMFNHLSAVSESIAALGWIAVSPKPGPYVKEMNDAATFYTNRVLRDYKHSDLRHVDWVRSYLKIWSELQAYIKEHHTTGLTWSKTGPVASTASAFSILSSGPGLPPPPPPPPPPGPPPPFENEGGKEEPSPSRSALFAQLNQGEAITKGLRHVTDDKKIYKNPSLRAQGQIRSPTKTRTPSPTSSKSNSPQKHAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCDKSTLQIKGKVNSITVDNCKKFGLVFDHVVGIVEVINSKDIQIQVMGRVPTISINKTEGCHLYLSKDALDCEIVSAKSSEMNVLVPQGDDYREFPIPEQFKTIWDGSKLITEPAEIMA", "length": 477 }, "evidence": [ { "id": "A0A8C2MYE4", "url": "https://omabrowser.org/oma/group/A0A8C2MYE4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CYT6-1", "protein_name": "Adenylyl cyclase-associated protein 2", "gene_name": "Cap2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTDMAGLMERLERAVIRLEQLSAGLDGPPRGCGEVNGVNGGVAPSVEAFDKLINSMVAEFLKNSRVLAGDVETHAEMVHGAFQAQRAFLLMVSQYQQPQENEVAVLLKPISEKIQEIQTFRERNRGSNMFNHLSAVSESIAALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVRSYLNIWSELQAYIREHHTTGLTWSKTGPVASTASAFSILSSGPGLPPPPPPPPPPGPPPPFENEDKKEEPSPSRSALFAQLNQGEAITKGLRHVTDDKKTYKNPSLRAQGQIRSPTKTHTPSPTSPKSNSPQKHTPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCDKSTLQIKGKVNSITVDNCKKFGLVFDHVVGIVEVINSKDIQIQVMGRVPTISINKTEGCHLYLSEDALDCEIVSAKSSEMNVLVPQDDDYREFPIPEQFKTIWDGSKLVTEPAEIMA", "length": 476 }, "evidence": [ { "id": "A0A8C2MYE4", "url": "https://omabrowser.org/oma/group/A0A8C2MYE4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE4" } ], "pmid": "" }, { "name": "adenylate cyclase binding", "id": "GO:0008179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008179", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE4" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE4" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE4" } ], "pmid": "" }, { "name": "presynaptic actin cytoskeleton organization", "id": "GO:0099140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099140", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MYE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE4" }, { "id": "PS51329", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51329" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-CAP/cofactor C-like", "eco_id": "ECO_0000259", "start_pos": 317, "end_pos": 454, "start_aa": "Pro", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 310 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 413, "end_pos": 415 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N3G9-1", "uniprot_ac": "A0A8C2N3G9", "uniprot_id": "A0A8C2N3G9_CRIGR", "mass": { "chemical_mass": 96588.0, "monoisotopic_mass": 96588.0 }, "refseq": { "ac": "XP_027262900", "name": "metal transporter CNNM2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262900" }, "gene_names": [ { "name": "LOC100765482", "type": "recommended", "evidence": [ { "id": "A0A8C2N3G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9" } ] }, { "name": "LOC100765482", "type": "synonym", "evidence": [ { "id": "XP_027262900", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262900" } ] } ], "protein_names": [ { "name": "Metal transporter", "type": "recommended", "evidence": [ { "id": "A0A8C2N3G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9/entry#names_and_taxonomy" } ] }, { "name": "metal transporter CNNM2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027262900", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262900" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027262900", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262900" } ] }, { "annotation": "Metal transporter.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FLT7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLT7#function" }, { "database": "UniProtKB", "id": "RU369091", "url": "https://www.uniprot.org/uniprotkb/RU369091#function" }, { "database": "UniProtKB", "id": "A0A8C2MVS6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVS6#function" }, { "database": "UniProtKB", "id": "A0A8C2N3G9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3G9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100765482", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9", "locus": {} } ], "crossref": [ { "id": "cd04590", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04590", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765482", "url": "https://www.ncbi.nlm.nih.gov/gene/100765482", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765482", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765482", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N3G9", "url": "https://www.orthodb.org/?gene=A0A8C2N3G9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12064:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12064:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25511", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25511", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027262900", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262900", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MVS6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MVS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N3G9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N3G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FLT7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FLT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIGCGACEPEVKMAGGQAAAALPTWKMAARRSLSARGRGVLQAAAGRLLPLLLLSCCCGAGGCAAAGENEETVIIGLRLEDTNDVSFMEGGALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHTPGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPLRKMEKSKSYYLCTSLSTPALGSGSSGAASGAVGGKGGAGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPECYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVPLSLSRTFVVSRTEVLAAGSPGENKSPPRPCGLNHSDSLSRSDRIDAMTPTLGSSNNQLNSSFLQVYIPDYSVRALSDLQFVKISRQQYQNALMASRMDKTPQSSDSENTKIELTLTELHDGLPDETANLLNEQNCVSHNKANHSLHSEGAI", "length": 875, "header": "tr|A0A8C2N3G9-1|A0A8C2N3G9_CRIGR Isoform 1 of Metal transporter OS=Cricetulus griseus OX=10029 GN=LOC100765482 PE=3 SV=1 CANONICAL=A0A8C2N3G9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MVS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9/entry#A0A8C2MVS6-1", "sequence": { "sequence": "MIGCGACEPEVKMAGGQAAAALPTWKMAARRSLSARGRGVLQAAAGRLLPLLLLSCCCGAGGCAAAGENEETVIIGLRLEDTNDVSFMEGGALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHTPGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPLRKMEKSKSYYLCTSLSTPALGSGSSGAASGAVGGKGGAGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPECYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPGENKSPPRPCGLNHSDSLSRSDRIDAMTPTLGSSNNQLNSSFLQVYIPDYSVRALSDLQFVKISRQQYQNALMASRMDKTPQSSDSENTKIELTLTELHDGLPDETANLLNEQNCVSHNKANHSLHSEGAI", "length": 853, "header": "tr|A0A8C2MVS6-1|A0A8C2N3G9_CRIGR Computationally mapped isoform of Metal transporter OS=Cricetulus griseus OX=10029 GN=LOC100765482 PE=3 SV=1 CANONICAL=A0A8C2N3G9-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N3G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9/entry#A0A8C2N3G9-1", "sequence": { "sequence": "MIGCGACEPEVKMAGGQAAAALPTWKMAARRSLSARGRGVLQAAAGRLLPLLLLSCCCGAGGCAAAGENEETVIIGLRLEDTNDVSFMEGGALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHTPGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPLRKMEKSKSYYLCTSLSTPALGSGSSGAASGAVGGKGGAGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPECYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVPLSLSRTFVVSRTEVLAAGSPGENKSPPRPCGLNHSDSLSRSDRIDAMTPTLGSSNNQLNSSFLQVYIPDYSVRALSDLQFVKISRQQYQNALMASRMDKTPQSSDSENTKIELTLTELHDGLPDETANLLNEQNCVSHNKANHSLHSEGAI", "length": 875, "header": "tr|A0A8C2N3G9-1|A0A8C2N3G9_CRIGR Isoform 1 of Metal transporter OS=Cricetulus griseus OX=10029 GN=LOC100765482 PE=3 SV=1 CANONICAL=A0A8C2N3G9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FLT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9/entry#A0A9J7FLT7-1", "sequence": { "sequence": "MIGCGACEPEVKMAGGQAAAALPTWKMAARRSLSARGRGVLQAAAGRLLPLLLLSCCCGAGGCAAAGENEETVIIGLRLEDTNDVSFMEGGALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHTPGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPLRKMEKSKSYYLCTSLSTPALGSGSSGAASGAVGGKGGAGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGLITEQRPSFPCPLALYAVTIIMSLKTWGSGKPGRYSEEALCSLYVRNKGIWVWGLHLISKHVLR", "length": 605, "header": "tr|A0A9J7FLT7-1|A0A8C2N3G9_CRIGR Computationally mapped isoform of Metal transporter OS=Cricetulus griseus OX=10029 GN=LOC100765482 PE=3 SV=1 CANONICAL=A0A8C2N3G9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FLT7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLT7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FLT7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLT7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765482", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765482", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3G9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3G9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3G9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "magnesium ion homeostasis", "id": "GO:0010960", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010960", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3G9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9" } ], "pmid": "" }, { "name": "positive regulation of multicellular organism growth", "id": "GO:0040018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040018", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3G9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9" } ], "pmid": "" }, { "name": "determination of adult lifespan", "id": "GO:0008340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008340", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3G9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9" } ], "pmid": "" }, { "name": "response to magnesium ion", "id": "GO:0032026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032026", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3G9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9" } ], "pmid": "" }, { "name": "positive regulation of gonad development", "id": "GO:1905941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905941", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3G9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "magnesium ion transmembrane transporter activity", "id": "GO:0015095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015095", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3G9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3G9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 527, "end_pos": 529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" }, { "start_pos": 747, "end_pos": 749, "annotation": "n_glycosylation_sequon" }, { "start_pos": 757, "end_pos": 759, "annotation": "n_glycosylation_sequon" }, { "start_pos": 783, "end_pos": 785, "annotation": "n_glycosylation_sequon" }, { "start_pos": 866, "end_pos": 868, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N3G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9" }, { "id": "PS51371", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51371" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CBS", "eco_id": "ECO_0000259", "start_pos": 518, "end_pos": 584, "start_aa": "Tyr", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N3G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3G9" }, { "id": "PS51846", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51846" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CNNM transmembrane", "eco_id": "ECO_0000259", "start_pos": 251, "end_pos": 431, "start_aa": "Phe", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 327, "end_pos": 329 }, { "start_pos": 527, "end_pos": 529 }, { "start_pos": 591, "end_pos": 593 }, { "start_pos": 747, "end_pos": 749 }, { "start_pos": 757, "end_pos": 759 }, { "start_pos": 783, "end_pos": 785 }, { "start_pos": 866, "end_pos": 868 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MXF5-1", "uniprot_ac": "A0A8C2MXF5", "uniprot_id": "A0A8C2MXF5_CRIGR", "mass": { "chemical_mass": 88431.0, "monoisotopic_mass": 88431.0 }, "refseq": { "ac": "XP_003501549", "name": "transducin beta-like protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501549" }, "gene_names": [ { "name": "Tbl3", "type": "recommended", "evidence": [ { "id": "A0A8C2MXF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF5" } ] }, { "name": "Tbl3", "type": "synonym", "evidence": [ { "id": "XP_003501549", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501549" } ] } ], "protein_names": [ { "name": "Transducin beta-like protein 3", "type": "recommended", "evidence": [ { "id": "A0A8C2MXF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF5/entry#names_and_taxonomy" } ] }, { "name": "transducin beta-like protein 3", "type": "synonym", "evidence": [ { "id": "XP_003501549", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501549" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613852.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003501549", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501549" } ] }, { "annotation": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXF5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF5#function" }, { "database": "UniProtKB", "id": "ARBA00035000", "url": "https://www.uniprot.org/uniprotkb/ARBA00035000#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXF5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tbl3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF5", "locus": {} } ], "crossref": [ { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754975", "url": "https://www.ncbi.nlm.nih.gov/gene/100754975", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754975", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754975", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PYVQRHF", "url": "https://omabrowser.org/oma/group/PYVQRHF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MXF5", "url": "https://www.orthodb.org/?gene=A0A8C2MXF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19854", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19854", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19854:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19854:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003501549", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501549", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MXF5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MXF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAETAAGVSRFKANYAIERKIEPFYKGGKAQLDRTGHHLFCVCGTKVNILDVASGALLRSLEQEDQEDITAFDLSPDNEVLVTASRALLLAQWAWREGTVTRLWKAIHTAPVASMAFDATSTLLATGGCDGAIRVWDIVQHYGTHHLRGSPGVVHLVAFHPDPTRLLLFSSAVDTSIRMWSLQDRSCVAVLTAHYSAVTSLSFSEDGHTMLSSGRDKICIVWDLQSYQATRTVPVFESIEAAVLLPEEPAPALGVKNSGLHFLTAGDQGILRVWEAASGQCVYTQPQMPGLGQELTHCTLARTAGLLLTVTTDHNLLLYEAHSLQLQKQFAGYSEEVLDVRFLGPNDSHIVVASNSPCLKVFELQTLACQILHGHTDIVLALDVFRKGWLFVSCAKDQSIRIWRMNKAGQVTCVAQGSGHTHSVGTICCSRLKESFLVTGSQDCTVKLWPLPEALLSKNIAVDSGPMLLQAQTTQRCHDKDINSLAVSPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWNVQFSPTDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGSQLLSSGSDGLLKLWTIKSNECVRTLDAHEDKVWGLHCSRLDDHAITGGSDSRIILWKDVTEAEQAEEQAKREEQVIKQQELDNLLHEKRYLRAVGLAISLDRPHTVLTVIQAIRRDPEACEKLEDTVLRLRRDQKEALLRFCVTWNTNSRHCHEAQAVLGVLLRHETPEELLAYEGVRGTLEALLPYTERHFQRLSRTLQAATFLDFLWHNMKLSPLPAAPPAL", "length": 800, "header": "tr|A0A8C2MXF5-1|A0A8C2MXF5_CRIGR Isoform 1 of Transducin beta-like protein 3 OS=Cricetulus griseus OX=10029 GN=Tbl3 PE=4 SV=1 CANONICAL=A0A8C2MXF5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MXF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF5/entry#A0A8C2MXF5-1", "sequence": { "sequence": "MAETAAGVSRFKANYAIERKIEPFYKGGKAQLDRTGHHLFCVCGTKVNILDVASGALLRSLEQEDQEDITAFDLSPDNEVLVTASRALLLAQWAWREGTVTRLWKAIHTAPVASMAFDATSTLLATGGCDGAIRVWDIVQHYGTHHLRGSPGVVHLVAFHPDPTRLLLFSSAVDTSIRMWSLQDRSCVAVLTAHYSAVTSLSFSEDGHTMLSSGRDKICIVWDLQSYQATRTVPVFESIEAAVLLPEEPAPALGVKNSGLHFLTAGDQGILRVWEAASGQCVYTQPQMPGLGQELTHCTLARTAGLLLTVTTDHNLLLYEAHSLQLQKQFAGYSEEVLDVRFLGPNDSHIVVASNSPCLKVFELQTLACQILHGHTDIVLALDVFRKGWLFVSCAKDQSIRIWRMNKAGQVTCVAQGSGHTHSVGTICCSRLKESFLVTGSQDCTVKLWPLPEALLSKNIAVDSGPMLLQAQTTQRCHDKDINSLAVSPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWNVQFSPTDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGSQLLSSGSDGLLKLWTIKSNECVRTLDAHEDKVWGLHCSRLDDHAITGGSDSRIILWKDVTEAEQAEEQAKREEQVIKQQELDNLLHEKRYLRAVGLAISLDRPHTVLTVIQAIRRDPEACEKLEDTVLRLRRDQKEALLRFCVTWNTNSRHCHEAQAVLGVLLRHETPEELLAYEGVRGTLEALLPYTERHFQRLSRTLQAATFLDFLWHNMKLSPLPAAPPAL", "length": 800, "header": "tr|A0A8C2MXF5-1|A0A8C2MXF5_CRIGR Isoform 1 of Transducin beta-like protein 3 OS=Cricetulus griseus OX=10029 GN=Tbl3 PE=4 SV=1 CANONICAL=A0A8C2MXF5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXF5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXF5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754975", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754975", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q05946-1", "protein_name": "U3 small nucleolar RNA-associated protein 13", "gene_name": "UTP13", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDLKTSYKGISLNPIYAGSSAVATVSENGKILATPVLDEINIIDLTPGSRKILHKISNEDEQEITALKLTPDGQYLTYVSQAQLLKIFHLKTGKVVRSMKISSPSYILDADSTSTLLAVGGTDGSIIVVDIENGYITHSFKGHGGTISSLKFYGQLNSKIWLLASGDTNGMVKVWDLVKRKCLHTLQEHTSAVRGLDIIEVPDNDEPSLNLLSGGRDDIINLWDFNMKKKCKLLKTLPVNQQVESCGFLKDGDGKRIIYTAGGDAIFQLIDSESGSVLKRTNKPIEELFIIGVLPILSNSQMFLVLSDQTLQLINVEEDLKNDEDTIQVTSSIAGNHGIIADMRYVGPELNKLALATNSPSLRIIPVPDLSGPEASLPLDVEIYEGHEDLLNSLDATEDGLWIATASKDNTAIVWRYNENSCKFDIYAKYIGHSAAVTAVGLPNIVSKGYPEFLLTASNDLTIKKWIIPKPTASMDVQIIKVSEYTRHAHEKDINALSVSPNDSIFATASYDKTCKIWNLENGELEATLANHKRGLWDVSFCQYDKLLATSSGDKTVKIWSLDTFSVMKTLEGHTNAVQRCSFINKQKQLISCGADGLIKIWDCSSGECLKTLDGHNNRLWALSTMNDGDMIVSADADGVFQFWKDCTEQEIEEEQEKAKLQVEQEQSLQNYMSKGDWTNAFLLAMTLDHPMRLFNVLKRALGESRSRQDTEEGKIEVIFNEELDQAISILNDEQLILLMKRCRDWNTNAKTHTIAQRTIRCILMHHNIAKLSEIPGMVKIVDAIIPYTQRHFTRVDNLVEQSYILDYALVEMDKLF", "length": 817 }, "evidence": [ { "id": "A0A8C2MXF5", "url": "https://omabrowser.org/oma/group/A0A8C2MXF5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q12788-1", "protein_name": "Transducin beta-like protein 3", "gene_name": "TBL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAETAAGVGRFKTNYAVERKIEPFYKGGKAQLDQTGQHLFCVCGTRVNILEVASGAVLRSLEQEDQEDITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILWKDVTEAEQAEEQARQEEQVVRQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATMLRLRRDQKEALLRFCVTWNTNSRHCHEAQAVLGVLLRREAPEELLAYEGVRAALEALLPYTERHFQRLSRTLQAAAFLDFLWHNMKLPVPAAAPTPWETHKGALP", "length": 808 }, "evidence": [ { "id": "A0A8C2MXF5", "url": "https://omabrowser.org/oma/group/A0A8C2MXF5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5U2W5-1", "protein_name": "Transducin beta-like protein 3", "gene_name": "Tbl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAETAAGLCRFKANYAVERKIEPFYKGGKAQLDQTGRHLFCVCGTKVNILDVASGDLIRSLEQEDQEDITAFDLSPDDEVLVTASRALLLAQWAWREGTVARLWKAIHTAPVASMAFDATSTLLATGGCDGAVRVWDIVQHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSAVDTSIRVWSLQDRSCLAVLTAHYSAVTSLSFSEDGHTMLSSGRDKICIVWDLRSYETSRTVPVFESVEASVLLPEEPALALGVKNSGLHFLTAGDQGILRVWEAASGQCVYTQPQMSGLRQELTHCTLARAAGLLLTVTADHNLLLYEARSLQLQKQFAGYSEEVLDVRFLGPNDSHIIVASNSPCLKVFELQTLACQILHGHTDIVLALDVFRKGWLFASCAKDQSIRIWRMNKAGQVACVAQGSGHTHSVGTICCSRLKESFLVTGSQDCTVKLWPLPEALPSKNTASDGDLIPLQAQSTQRCHDKDINSLAVSPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWNVQFSPTDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGAQLLSSGSDGLLKLWTIKSNECVRTLDAHEDKVWGLHCSRLDDHAITGGSDSRIILWKDVTEAEQAEEQAKREEQVIKQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATVLRLRRDQKEALLRFCITWNTNSRHCHEAQAVLGVLLRHEAPEELLAYDGVRGALEALLPYTERHFQRLSRTLQAATFLDFLWHNMKLSPLPAAPPAL", "length": 800 }, "evidence": [ { "id": "A0A8C2MXF5", "url": "https://omabrowser.org/oma/group/A0A8C2MXF5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7KWS8-1", "protein_name": "WD40 repeat-containing protein", "gene_name": "utp13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIRYVECEPVTDDEEFQDEQPIQKVEPKAPSRKLKTVFKPDYEIGSLFTGGSLRISEDSKFIVSQAGYEIKIIDTEHGTVISKIESDTKISTFALSPNNEEILIGCSNLQIKQYRIEDQSLVKIWKGHEGPINEIDIHSSGNIVASASSDKTVKVWDLEKGYCTHNFQHDDVVTMLKFHPTLLKLVTVCLDLNIRVYDLVTKECVILTNHLSQISGITFSNSGKELISSGRDKVLNVWDMLSKNPKKTIPIYQELGGIITLPKESYNSLPENSKIKIEKIREKVKTMAAHADKIKNGDDITIVIGGEEVLRAWCTETGECIWNDQNIEFKKKTDNDDKDKTDTLYTISSIINNKDKIISITSEHNLLIYNGKTLERQGEIIGYNDEIIDIKYINDDNIIVATNSNEIKTYDLNTKRAQVLRGHEDLVMSVDVSADGKHIISGSRDKSAMIWDLEKKESIAQLTGHTGVISCVALPKKPSTSMFAITASDDRTIKLWKGFSTTSSSGGDDSKKKDKKISASVTKIAHEKDINSISIAPNDKIFATASQDSYVKLWNVNNLEPITSIKAHRRGVWHVEFSPIDQCFLTCSADGTIKIWSLSDYTCLKTLEGHKGSVLKASFISFGMQIVSVASEGLIKLWNIKTNECLNTFEGHESKIWALSVAKDQERFITGGSDSKLIAWKDHTEIELEIQKKKEENQVLYKQHLDTAIRKKDYYSALKLALVLDQPRQTLNIFNSMYYDDQSIGESVIQGCIGRLSPNEVVKCLRFIRDWNTNSKFVSISQIVLNSIITSFKPDELSKLSVGEMPKLLESIIPYTDRHFQRIDKMLQKTYLIDFTIQSINPAASTLSMDRVETSHIDQNYKKSLDQLIKEPTKPMKKSIQTPTSQKKKEKKKTFFKSNANK", "length": 902 }, "evidence": [ { "id": "A0A8C2MXF5", "url": "https://omabrowser.org/oma/group/A0A8C2MXF5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8C4J7-1", "protein_name": "Transducin beta-like protein 3", "gene_name": "Tbl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETAAGLCRFKANYAVERKIEPFYKGGKAQLDQTGHYLFCVCGTKVNILDVASGALLRSLEQEDQEDITSFDLSPDDEVLVTASRALLLAQWAWREGTVTRLWKAIHTAPVASMAFDATSTLLATGGCDGAVRVWDIVQHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSAVDTSIRVWSLQDRSCLAVLTAHYSAVTSLSFSEGGHTMLSSGRDKICIVWDLQSYQTTRTVPVFESVEASVLLPEQPAPALGVKSSGLHFLTAGDQGILRVWEAASGQCVYTQPQMPGLRQELTHCTLARAADLLLTVTADHNLLLYEAHSLQLQKQFAGYSEEVLDVRFLGPSDSHIVVASNSPCLKVFELQTLACQILHGHTDIVLALDVFRKGWLFASCAKDQSIRIWKMNKAGQVACVAQGSGHTHSVGTICCSRLKESFLVTGSQDCTVKLWPLPEALLAKSTAADSGPVLLQAQTTRRCHDKDINSLAVSPNDKLLATGSQDRTAKLWALPQCQLLGVFTGHRRGLWNVQFSPTDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGSQLLSSGSDGLLKLWTIKSNECVRTLDAHEDKVWGLHCSQLDDHAITGGSDSRIILWKDVTEAEQAEEQAKREEQVIKQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATVLRLRRDQKEALLRFCVTWNTNSRHCHEAQAVLGVLLRHEAPEELLAYDGVRGSLEALLPYTERHFQRLSRTLQAATFLDFLWHNMKLSPCPAAAPPAL", "length": 801 }, "evidence": [ { "id": "A0A8C2MXF5", "url": "https://omabrowser.org/oma/group/A0A8C2MXF5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LFE2-1", "protein_name": "Protein TORMOZ EMBRYO DEFECTIVE", "gene_name": "TOZ", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269703", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269703" } ] }, { "annotation": "Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on eukaryotic initiation factor 2 (eIF2) gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXF7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF7#function" }, { "database": "UniProtKB", "id": "ARBA00043898", "url": "https://www.uniprot.org/uniprotkb/ARBA00043898#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXF7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Eif2b1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF7", "locus": {} } ], "crossref": [ { "id": "100770460", "url": "https://www.ncbi.nlm.nih.gov/gene/100770460", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042528", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042528", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770460", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770460", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MXF7", "url": "https://www.orthodb.org/?gene=A0A8C2MXF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45860:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45860:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269703", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269703", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MXF7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MXF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDHELIEYFKSQMKGDPNMASAVAAIRTLLEFLKRDKGETLQGLRANLTSAIETLCSVDSSVAVSSGGELFLRFISLTSLEYSDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGARILTHAYSRVVLRVLEEAVAAKKRFSVYITESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKSKQTGQDLKEEHPWVDYTSPSLITLLFTDLGVLTPSAVSDELIKLYL", "length": 305, "header": "tr|A0A8C2MXF7-1|A0A8C2MXF7_CRIGR Isoform 1 of Translation initiation factor eIF2B subunit alpha OS=Cricetulus griseus OX=10029 GN=Eif2b1 PE=3 SV=1 CANONICAL=A0A8C2MXF7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MXF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF7/entry#A0A8C2MXF7-1", "sequence": { "sequence": "MEDHELIEYFKSQMKGDPNMASAVAAIRTLLEFLKRDKGETLQGLRANLTSAIETLCSVDSSVAVSSGGELFLRFISLTSLEYSDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGARILTHAYSRVVLRVLEEAVAAKKRFSVYITESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKSKQTGQDLKEEHPWVDYTSPSLITLLFTDLGVLTPSAVSDELIKLYL", "length": 305, "header": "tr|A0A8C2MXF7-1|A0A8C2MXF7_CRIGR Isoform 1 of Translation initiation factor eIF2B subunit alpha OS=Cricetulus griseus OX=10029 GN=Eif2b1 PE=3 SV=1 CANONICAL=A0A8C2MXF7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXF7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXF7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770460", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770460", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cytoplasmic translational initiation", "id": "GO:0002183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002183", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXF7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXF7" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": 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analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027277619", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277619" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXJ4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Snrpb", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXJ4", "locus": {} } ], "crossref": [ { "id": "cd01717", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01717", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751537", "url": "https://www.ncbi.nlm.nih.gov/gene/100751537", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751537", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751537", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MXJ4", "url": "https://www.orthodb.org/?gene=A0A8C2MXJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14508", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14508", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14508:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14508:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027277619", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277619", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MXJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MXJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGLL", "length": 231, "header": "tr|A0A8C2MXJ4-1|A0A8C2MXJ4_CRIGR Isoform 1 of Small nuclear ribonucleoprotein-associated protein OS=Cricetulus griseus OX=10029 GN=Snrpb PE=3 SV=1 CANONICAL=A0A8C2MXJ4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MXJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXJ4/entry#A0A8C2MXJ4-1", "sequence": { "sequence": "MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGLL", "length": 231, "header": "tr|A0A8C2MXJ4-1|A0A8C2MXJ4_CRIGR Isoform 1 of Small nuclear ribonucleoprotein-associated protein OS=Cricetulus griseus OX=10029 GN=Snrpb PE=3 SV=1 CANONICAL=A0A8C2MXJ4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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{ "database": "UniProtKB", "id": "A0A8C2MXJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXJ4" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MXJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXJ4" }, { "id": "PS52002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sm", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 86, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241885" } ] } ], "protein_names": [ { "name": "HEPACAM family member 2", "type": "recommended", "evidence": [ { "id": "A0A8C2MXP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP3/entry#names_and_taxonomy" } ] }, { "name": "HEPACAM family member 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027241885", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241885" } ] }, { "name": "Mitotic kinetics regulator", "type": "synonym", "evidence": [ { "id": "A0A8C2MXP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613638.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027241885", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241885" } ] }, { "annotation": "Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes: anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXP3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP3#function" }, { "database": "UniProtKB", "id": "ARBA00059869", "url": "https://www.uniprot.org/uniprotkb/ARBA00059869#function" }, { "database": "UniProtKB", "id": "A0A9J7H625", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H625#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXP3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Hepacam2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP3", "locus": {} } ], "crossref": [ { "id": "100765391", "url": "https://www.ncbi.nlm.nih.gov/gene/100765391", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765391", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765391", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TIDYMCC", "url": "https://omabrowser.org/oma/group/TIDYMCC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MXP3", "url": "https://www.orthodb.org/?gene=A0A8C2MXP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44888", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44888", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44888:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44888:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027241885", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241885", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MXP3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MXP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H625", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H625", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H625-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H625-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQDAFMESLSSMAGIFLCKIYFLLIAGVCSGLKVTVPSHTVHGIRGQALYLPVHYGFHTPASDIQIIWLFERSHTMPKYLLGSVNESVVPDLEYQHKFTMMPPNASLLINPLQFSDEGNYIVKVNIQGNGTLSSSQKIQVTVDDPVMKPVVQFYPASGAVEYVGNITLTCQVAGGTRLVYQWRKNGKPVCINSSHSLSPENNTLWIAPVTKEDVGNYSCLVSNPVSEMESDIIMPTIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSYPPNTYSWIQRSDNTTHVIQHGPRLEVASEKVAQKTTDYMCCAYNNITGKRDETHFTIIITSVGLEKLAQKGKSLSPLASITGISLFLIISMCLLFLWKKYQPYKAIRQKLRSRSESEYRKAQTFSGHEDALGDFGIYEFVTFPDASGVPRMPTRSAPASDGVTGHDFLGTIYEVIQHIPAQQQVNRE", "length": 463, "header": "tr|A0A8C2MXP3-1|A0A8C2MXP3_CRIGR Isoform 1 of HEPACAM family member 2 OS=Cricetulus griseus OX=10029 GN=Hepacam2 PE=4 SV=1 CANONICAL=A0A8C2MXP3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MXP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP3/entry#A0A8C2MXP3-1", "sequence": { "sequence": "MGQDAFMESLSSMAGIFLCKIYFLLIAGVCSGLKVTVPSHTVHGIRGQALYLPVHYGFHTPASDIQIIWLFERSHTMPKYLLGSVNESVVPDLEYQHKFTMMPPNASLLINPLQFSDEGNYIVKVNIQGNGTLSSSQKIQVTVDDPVMKPVVQFYPASGAVEYVGNITLTCQVAGGTRLVYQWRKNGKPVCINSSHSLSPENNTLWIAPVTKEDVGNYSCLVSNPVSEMESDIIMPTIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSYPPNTYSWIQRSDNTTHVIQHGPRLEVASEKVAQKTTDYMCCAYNNITGKRDETHFTIIITSVGLEKLAQKGKSLSPLASITGISLFLIISMCLLFLWKKYQPYKAIRQKLRSRSESEYRKAQTFSGHEDALGDFGIYEFVTFPDASGVPRMPTRSAPASDGVTGHDFLGTIYEVIQHIPAQQQVNRE", "length": 463, "header": "tr|A0A8C2MXP3-1|A0A8C2MXP3_CRIGR Isoform 1 of HEPACAM family member 2 OS=Cricetulus griseus OX=10029 GN=Hepacam2 PE=4 SV=1 CANONICAL=A0A8C2MXP3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H625-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP3/entry#A0A9J7H625-1", "sequence": { "sequence": "MGQDAFMESLSSMAGIFLCKIYFLLIGVCSGLKVTVPSHTVHGIRGQALYLPVHYGFHTPASDIQIIWLFERSHTMPKYLLGSVNESVVPDLEYQHKFTMMPPNASLLINPLQFSDEGNYIVKVNIQGNGTLSSSQKIQVTVDDPVMKPVVQFYPASGAVEYVGNITLTCQVAGGTRLVYQWRKNGKPVCINSSHSLSPENNTLWIAPVTKEDVGNYSCLVSNPVSEMESDIIMPTIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSYPPNTYSWIQRSDNTTHVIQHGPRLEVASEKVAQKTTDYMCCAYNNITGKRDETHFTIIITSVGLEKLAQKGKSLSPLASITGISLFLIISMCLLFLWKKYQPYKAIRQKLRSRSESEYRKAQTFSGHEDALGDFGIYEFVTFPDASGVPRMPTRSAPASDGVTGHDFLGTIYEVIQHIPAQQQVNRE", "length": 462, "header": "tr|A0A9J7H625-1|A0A9J7H625_CRIGR Computationally mapped isoform of HEPACAM family member 2 OS=Cricetulus griseus OX=10029 GN=Hepacam2 PE=4 SV=1 CANONICAL=A0A8C2MXP3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXP3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXP3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765391", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765391", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XFR9-1", "protein_name": "HEPACAM family member 2", "gene_name": "HEPACAM2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLSWSPLASLFCDLNCHIYFLLVGICSALKLTVPSHTIHGVEGQPLQLTVDYNFNTTACEIQIIWLFEKPQSNPKYLLGSVNQTVVPDLEYQHKFTLIPPNASLMINLLRTSDEGNYIVKVNVRGNGTIAASERIHVAVDVPVTQPIVQTEPSSGVVEYVGNITLKCTVGKGTRVVYQWMKNGKPLHAGPNYTFSSNNATLLIVPVAKEDIGNYSCLVSNPVSAMESERIVPTIYYGPYGLRVKSDKGLNVGAVFTVNVGEAVLFDCSADSNPPNTYSWIQRADNTTHVIQYGPHLEVVSDTVAQKTRDYVCRAFNNMTGKRDETHFTVIITSAGLEKLAQKGKSLSSLAVITGISLFLILVMSFLFIWKRYKPLQVIQQKLRRRPEADYRKAQTFSGHESALDDFGIYEFVAIPDHASGSRVSSQPVHTSDSASGQDMLSTVYEVIQHIPNQQQQDHQQCI", "length": 462 }, "evidence": [ { "id": "A0A8C2MXP3", "url": "https://omabrowser.org/oma/group/A0A8C2MXP3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A6QQC6-1", "protein_name": "HEPACAM family member 2", "gene_name": "HEPACAM2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWLRVFTAFLSFTAGACSGLKVAVPSHTVHGIRGQALYLPVHYGFHTPASDIQVIWLFERPHTMPKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLINPLQFTDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIQPSSGAVEYVGNMTLTCLVEGGSRRVYQWLKNGRPVHTSSTNSFSLQNSSLHIAPVTKEDIGNYSCLVKNPVSRMESDIIMPTIYYGPYGLRVNSDRGLKVGEVFTVDIGEAILFDCSADSYPPNTYSWIQRTNNATYVIKHGPRLEVASEKIAQKTTDYMCCAYNNITGRRDETHFTVIITSVGIEKLAQKGKSLSPLASITGISLFLIISMCLLFLWKKFQPYKVIKQKLEGRPETEYRKARTFSGHEDALDDFGIYEFVAFPDASGVARMPARSVPACDGVPGQDLHSTIYEVIHHIPAQQQDHPESSSQDGEEDACLDRHDEAGLQELGHCKEQDKGKHSRAKQCI", "length": 491 }, "evidence": [ { "id": "A0A8C2MXP3", "url": "https://omabrowser.org/oma/group/A0A8C2MXP3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A8MVW5-1", "protein_name": "HEPACAM family member 2", "gene_name": "HEPACAM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQDAFMEPFGDTLGVFQCKIYLLLFGACSGLKVTVPSHTVHGVRGQALYLPVHYGFHTPASDIQIIWLFERPHTMPKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVIITSVGLEKLAQKGKSLSPLASITGISLFLIISMCLLFLWKKYQPYKVIKQKLEGRPETEYRKAQTFSGHEDALDDFGIYEFVAFPDVSGVSRIPSRSVPASDCVSGQDLHSTVYEVIQHIPAQQQDHPE", "length": 462 }, "evidence": [ { "id": "A0A8C2MXP3", "url": "https://omabrowser.org/oma/group/A0A8C2MXP3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q4VAH7-1", "protein_name": "HEPACAM family member 2", "gene_name": "Hepacam2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616689.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003514568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514568" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100761706", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP9", "locus": {} } ], "crossref": [ { "id": "cd07141", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07141", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761706", "url": "https://www.ncbi.nlm.nih.gov/gene/100761706", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761706", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761706", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WPLYQIT", "url": "https://omabrowser.org/oma/group/WPLYQIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MXP9", "url": "https://www.orthodb.org/?gene=A0A8C2MXP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11699", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11699", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003514568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514568", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MXP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MXP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSPAQPEVPAPLANLKIQYTKIFINNEWYDSVSGKKFPVFNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLFKLADLVERDRLLLTTMESMNSGRLFTQSYTIDFEIIIKGLKYCAAWADKIHGQTIPSDGDIFTYTKREPIGVCGQIIPWNGPLLMFIWKIGPALSCGNTVIVKPAEQTPLTALHMASLIKEAGFPPGVVNVVPGYGPTAGAAISSHMDIDKVSFTGSTEVGKLITEAAGKSNLKRVTLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQICVAASRLFVEESIYDEFVKRSVERAKKYVLGNPLNLGINQGPQIDKEQHDKILQLIESGKKEGAKLELGGGRWGNKGYFVQPTVFSNVTDDMRIAKEEIFGPVQQIMKFKSIDDVIKRANNTSYGLAAGVFTKDLDKAITLSSALQAGIVWVNCYLALSVQCPFGGFKMSGNGREMGESGIYEYTELKTVAMKISQKNS", "length": 501, "header": "tr|A0A8C2MXP9-1|A0A8C2MXP9_CRIGR Isoform 1 of aldehyde dehydrogenase (NAD(+)) OS=Cricetulus griseus OX=10029 GN=LOC100761706 PE=3 SV=1 CANONICAL=A0A8C2MXP9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MXP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP9/entry#A0A8C2MXP9-1", "sequence": { "sequence": "MSSPAQPEVPAPLANLKIQYTKIFINNEWYDSVSGKKFPVFNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLFKLADLVERDRLLLTTMESMNSGRLFTQSYTIDFEIIIKGLKYCAAWADKIHGQTIPSDGDIFTYTKREPIGVCGQIIPWNGPLLMFIWKIGPALSCGNTVIVKPAEQTPLTALHMASLIKEAGFPPGVVNVVPGYGPTAGAAISSHMDIDKVSFTGSTEVGKLITEAAGKSNLKRVTLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQICVAASRLFVEESIYDEFVKRSVERAKKYVLGNPLNLGINQGPQIDKEQHDKILQLIESGKKEGAKLELGGGRWGNKGYFVQPTVFSNVTDDMRIAKEEIFGPVQQIMKFKSIDDVIKRANNTSYGLAAGVFTKDLDKAITLSSALQAGIVWVNCYLALSVQCPFGGFKMSGNGREMGESGIYEYTELKTVAMKISQKNS", "length": 501, "header": "tr|A0A8C2MXP9-1|A0A8C2MXP9_CRIGR Isoform 1 of aldehyde dehydrogenase (NAD(+)) OS=Cricetulus griseus OX=10029 GN=LOC100761706 PE=3 SV=1 CANONICAL=A0A8C2MXP9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXP9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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This record is derived from a genomic sequence (NW_003613687.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003498334.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003498334", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498334" } ] }, { "annotation": "Assembly factor for cytochrome c oxidase (respiratory chain complex IV). 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CANONICAL=A0A8C2MXU6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MXU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXU6/entry#A0A8C2MXU6-1", "sequence": { "sequence": "MARTAPVEPPLRHPAPPSPAAGEPRASVEAAVAPRRVLFADEALGLPLAQLRRYRPWGGPGAGKMAAETGQDGGGGGADEDDDGEDGDEGEEEEEAFPDPSPLCPVPAGGGFYLVPTFSLPPALGRLERLGRVMVELEALLPPPGAVPGGSGVWVPGGRPPVVRGLVRVLNRSFEKAVHVRASHDGWASFCDHPARYVPRSLPGAGVGGTGAGDPLLDPGLGLGPGQMSASSPDDGGRTDRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPTPTDAEGLIQQQQLQQLEPQPECQGPVEAEARQLKSCMKPVRRRPLEEELRMKSTDDNALSEHPDVHGSLGPLVAPTPLRPWPQMTLRVSEATVTNNPWEEGDIPRSNPPVAFTEVLQTPAIRILPSTRGLRGPPKDQASGPDASDRATGPFLEPSQHQVEATWESGVGRKAPTVGAMTDEPARGLEIVSGLEELLGEDTIDQELEQLYLSHLSRLRAVASGAGGEGSTDGGMSPSHPLGILTDRDLILKWPGPERALNSALAEEITLHYARLGCGVELIKDTEDPDDEGEGEEGLSITPSSPEGDTPKESPPEIVSGARSVVAMGDVWLPWAEGSGCDSPVVVGTQGQFTENPEKGMDKDINSLHMNRPIDGVARSPGEAGTEAPMEVPTEWAGSLIPISDKEPPAPVLPEQSPSLLSPPGTEVCLSSVANPHVTSQDEEGGSLNLESPERSPMPAAPAECVCGLSPQLRGPLTQTLGVLAGLIVVPVALNSGMSLLVLVLCLSLAWFS", "length": 800, "header": "tr|A0A8C2MXU6-1|A0A8C2MXU6_CRIGR Isoform 1 of Protein phosphatase 1 regulatory subunit 3F isoform X2 OS=Cricetulus griseus OX=10029 GN=Ppp1r3f PE=4 SV=1 CANONICAL=A0A8C2MXU6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 210, "start_aa": "Thr", "end_pos": 210, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr210", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 291, "start_aa": "Thr", "end_pos": 291, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr291", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 293, "start_aa": "Thr", "end_pos": 293, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr293", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXU6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXU6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXU6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXU6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767964", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767964", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "protein phosphatase type 1 complex", "id": "GO:0000164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000164", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXU6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXU6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXU6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXU6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXU6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXU6" } ], "pmid": "" }, { "name": "glycogen binding", "id": "GO:2001069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001069", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXU6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXU6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of glycogen biosynthetic process", "id": "GO:0005979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005979", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXU6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXU6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MXU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXU6" }, { "id": "PS51159", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51159" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CBM21", "eco_id": "ECO_0000259", "start_pos": 127, "end_pos": 283, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 210, 291, 293 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 }, { "start_pos": 279, "end_pos": 281 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MXZ6-1", "uniprot_ac": "A0A8C2MXZ6", "uniprot_id": "A0A8C2MXZ6_CRIGR", "mass": { "chemical_mass": 113152.0, "monoisotopic_mass": 113152.0 }, "refseq": { "ac": "XP_027274547", "name": "isoleucine--tRNA ligase, mitochondrial isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274547" }, "gene_names": [ { "name": "Iars2", "type": "recommended", "evidence": [ { "id": "A0A8C2MXZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6" } ] }, { "name": "Iars2", "type": "synonym", "evidence": [ { "id": "XP_027274547", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274547" } ] } ], "protein_names": [ { "name": "Isoleucine--tRNA ligase, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8C2MXZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6/entry#names_and_taxonomy" } ] }, { "name": "6.1.1.5", "type": "synonym", "evidence": [ { "id": "A0A8C2MXZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6/entry#names_and_taxonomy" } ] }, { "name": "Isoleucyl-tRNA synthetase", "type": "synonym", "evidence": [ { "id": "A0A8C2MXZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6/entry#names_and_taxonomy" } ] }, { "name": "isoleucine--tRNA ligase, mitochondrial isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027274547", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274547" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027274547", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274547" } ] }, { "annotation": "Aminoacyl-tRNA synthetase that catalyzes the specific attachment of isoleucine to its cognate tRNA (tRNA(Ile)).", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6#function" }, { "database": "UniProtKB", "id": "ARBA00055883", "url": "https://www.uniprot.org/uniprotkb/ARBA00055883#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Iars2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6", "locus": {} } ], "crossref": [ { "id": "cd07960", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07960", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758227", "url": "https://www.ncbi.nlm.nih.gov/gene/100758227", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010663", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010663", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033708", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033708", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758227", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758227", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MXZ6", "url": "https://www.orthodb.org/?gene=A0A8C2MXZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42765", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42765", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42765:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42765:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06827", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06827", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08264", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08264", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027274547", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274547", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11060", "url": "https://www.rhea-db.org/rhea/11060", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MXZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MXZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRWGLRPHGPGAAALAAAGSFWRPARCPGRLGCPGVTRRLVVRSVAGADSPQSSANRGRYRDTVLLPQTSFPMKLLGRQQPDMELEIQQKCGFSELYSWQRERKGKTEFCLHDGPPYANGDPHIGHALNKILKDIANRYHMMRGSKVHFVPGWDCHGLPIETKVLSELGVSAQTLSAMEIREKARSFAKAAIEKQKSAFARWGVMADWNNCYYTFDAKYEAKQLRLFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEYNPEHVSRSIYVRFPLLQPPPKLASLTDGSSPVSFLIWTTQPWTIPANQAVCYMPEAKYAVVKCSSSGDIYILAEDKISPVASALETTFEVISTFSGVDLEGGTCSHPLIPDKVSPLLPATHVTMAKGTGLVHTAPAHGMEDYSVASQHNLPMDCLVDEDGVFTDAAGPELENKAVLEEGTDVVIKMLQTAKHLLKEEKVVHSYPCDWRTKKPVVIRASKQWFINIKDIKATAKELLKTVKFIPGAALNGMVDLLDRRPYWCISRQRAWGVPIPVFHHKTKDEYLINSQTIEHITKLVEEHGSDVWWTLPPERLLPEDVVAQAGGPDALEYVPGQDILDIWFDSGTSWFCVLPGTEQRADLYLEGKDQLGGWFQSSLLTRVATKTKAPFKTVMVHGFTLGEKGEKMSKSLGNVINPDTIINGGKDPSKEPPYGADALRWWIAESNVFTEVAIGPSALSAARDDISKLRNTLRFLLGNVAGFNPETDSVPVKDMYVIDQYMLHLIQDFSTKVTDSYKQYDFGKVIRLLKAFYTRELSSFYFSIVKDRLYCESEKDPKRRSCQTALAEILDVLVRSFAPILPHLAEEVFQHIPYVKEPKSVFRTGWINTSSIWKKPGLEEAVESTCAMRDSFLGSIPGKNAAEYEVTIVIEPGLLFEIMEMLQAEEISSTSQLNELMMASQTTLLTQEPRERAEDGIELTGSFLINLEGGDIREESSYKVIVVPAAREKCPRCWKHTAETADTLCPRCAEVIGAK", "length": 1012, "header": "tr|A0A8C2MXZ6-1|A0A8C2MXZ6_CRIGR Isoform 1 of Isoleucine--tRNA ligase, mitochondrial OS=Cricetulus griseus OX=10029 GN=Iars2 PE=3 SV=1 CANONICAL=A0A8C2MXZ6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MXZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6/entry#A0A8C2MXZ6-1", "sequence": { "sequence": "MRWGLRPHGPGAAALAAAGSFWRPARCPGRLGCPGVTRRLVVRSVAGADSPQSSANRGRYRDTVLLPQTSFPMKLLGRQQPDMELEIQQKCGFSELYSWQRERKGKTEFCLHDGPPYANGDPHIGHALNKILKDIANRYHMMRGSKVHFVPGWDCHGLPIETKVLSELGVSAQTLSAMEIREKARSFAKAAIEKQKSAFARWGVMADWNNCYYTFDAKYEAKQLRLFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEYNPEHVSRSIYVRFPLLQPPPKLASLTDGSSPVSFLIWTTQPWTIPANQAVCYMPEAKYAVVKCSSSGDIYILAEDKISPVASALETTFEVISTFSGVDLEGGTCSHPLIPDKVSPLLPATHVTMAKGTGLVHTAPAHGMEDYSVASQHNLPMDCLVDEDGVFTDAAGPELENKAVLEEGTDVVIKMLQTAKHLLKEEKVVHSYPCDWRTKKPVVIRASKQWFINIKDIKATAKELLKTVKFIPGAALNGMVDLLDRRPYWCISRQRAWGVPIPVFHHKTKDEYLINSQTIEHITKLVEEHGSDVWWTLPPERLLPEDVVAQAGGPDALEYVPGQDILDIWFDSGTSWFCVLPGTEQRADLYLEGKDQLGGWFQSSLLTRVATKTKAPFKTVMVHGFTLGEKGEKMSKSLGNVINPDTIINGGKDPSKEPPYGADALRWWIAESNVFTEVAIGPSALSAARDDISKLRNTLRFLLGNVAGFNPETDSVPVKDMYVIDQYMLHLIQDFSTKVTDSYKQYDFGKVIRLLKAFYTRELSSFYFSIVKDRLYCESEKDPKRRSCQTALAEILDVLVRSFAPILPHLAEEVFQHIPYVKEPKSVFRTGWINTSSIWKKPGLEEAVESTCAMRDSFLGSIPGKNAAEYEVTIVIEPGLLFEIMEMLQAEEISSTSQLNELMMASQTTLLTQEPRERAEDGIELTGSFLINLEGGDIREESSYKVIVVPAAREKCPRCWKHTAETADTLCPRCAEVIGAK", "length": 1012, "header": "tr|A0A8C2MXZ6-1|A0A8C2MXZ6_CRIGR Isoform 1 of Isoleucine--tRNA ligase, mitochondrial OS=Cricetulus griseus OX=10029 GN=Iars2 PE=3 SV=1 CANONICAL=A0A8C2MXZ6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758227", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758227", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "aminoacyl-tRNA deacylase activity", "id": "GO:0002161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002161", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6" } ], "pmid": "" }, { "name": "isoleucine-tRNA ligase activity", "id": "GO:0004822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004822", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "isoleucyl-tRNA aminoacylation", "id": "GO:0006428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006428", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MXZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6" } ], "pmid": "" }, { "name": "mitochondrial translation", "id": "GO:0032543", "url": 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"url": "https://www.rhea-db.org/rhea/11060" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8C2MXZ6", "gene_name": "Iars2", "activity": [ { "ec_number": "6.1.1.5", "activity": "tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate.", "evidence": [ { "id": "A0A8C2MXZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6" } ] }, { "ec_number": "6.1.1.5", "activity": "", "evidence": [ { "id": "A0A8C2MXZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXZ6" } ] } ] }, { "uniprot_ac": "G3HP24", "gene_name": "Iars1", "activity": [ { "ec_number": "6.1.1.5", "activity": "tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate.", "evidence": [ { "id": "G3HP24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HP24" } ] }, { "ec_number": "6.1.1.5", "activity": "", "evidence": [ { "id": "G3HP24", "database": "UniProtKB", "url": 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"name": "Regulator of G-protein signaling 10 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2MY05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05/entry#names_and_taxonomy" } ] }, { "name": "regulator of G-protein signaling 10 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027260271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260271" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260271" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rgs10", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05", "locus": {} } ], "crossref": [ { "id": "cd08741", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08741", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758318", "url": "https://www.ncbi.nlm.nih.gov/gene/100758318", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758318", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758318", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MY05", "url": "https://www.orthodb.org/?gene=A0A8C2MY05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45945", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45945", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45945:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45945:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027260271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260271", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MY05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MY05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFTRAVSRLSRKRPPSDIHDSDGSSSSSNQGPKSTAKWASSLETLLEDPEGVMRFREFLKKEFSEENVLFWLACEDFKKLEDKKQMQEKAKEIYMTFLSNKASSQVNVEGQSRLSEKFLEEPHPLMFQKLQEQIFNLMKYDSYSRFLKSDLFLKHNCTDEEEEEPPDAQTAAKRASRIYNT", "length": 181, "header": "tr|A0A8C2MY05-1|A0A8C2MY05_CRIGR Isoform 1 of Regulator of G-protein signaling 10 isoform X2 OS=Cricetulus griseus OX=10029 GN=Rgs10 PE=4 SV=1 CANONICAL=A0A8C2MY05-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MY05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05/entry#A0A8C2MY05-1", "sequence": { "sequence": "MFTRAVSRLSRKRPPSDIHDSDGSSSSSNQGPKSTAKWASSLETLLEDPEGVMRFREFLKKEFSEENVLFWLACEDFKKLEDKKQMQEKAKEIYMTFLSNKASSQVNVEGQSRLSEKFLEEPHPLMFQKLQEQIFNLMKYDSYSRFLKSDLFLKHNCTDEEEEEPPDAQTAAKRASRIYNT", "length": 181, "header": "tr|A0A8C2MY05-1|A0A8C2MY05_CRIGR Isoform 1 of Regulator of G-protein signaling 10 isoform X2 OS=Cricetulus griseus OX=10029 GN=Rgs10 PE=4 SV=1 CANONICAL=A0A8C2MY05-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758318", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758318", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05" } ], "pmid": "" }, { "name": "G-protein alpha-subunit binding", "id": "GO:0001965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001965", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled acetylcholine receptor signaling pathway", "id": "GO:0007213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007213", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MY05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY05" }, { "id": "PS50132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RGS", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 154, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MY21-1", "uniprot_ac": "A0A8C2MY21", "uniprot_id": "A0A8C2MY21_CRIGR", "mass": { "chemical_mass": 100880.0, "monoisotopic_mass": 100880.0 }, "refseq": { "ac": "XP_016831423", "name": "N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831423" }, "gene_names": [ { "name": "Naa16", "type": "recommended", "evidence": [ { "id": "A0A8C2MY21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY21" } ] }, { "name": "Naa16", "type": "synonym", "evidence": [ { "id": "XP_016831423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831423" } ] } ], "protein_names": [ { "name": "N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016831423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831423" } ] }, { "name": "N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X4", "type": "synonym", "evidence": [ { "id": "A0A8C2MY21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY21/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 199 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613940.1) and transcript sequence (IACG01030062.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016831423.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016831423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831423" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY21", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY21" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Naa16", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY21", "locus": {} } ], "crossref": [ { "id": "100771585", "url": "https://www.ncbi.nlm.nih.gov/gene/100771585", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013105", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013105", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771585", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771585", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MY21", "url": "https://www.orthodb.org/?gene=A0A8C2MY21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22767", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22767", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22767:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22767:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07719", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07719", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016831423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831423", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MY21", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MY21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J396", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J396", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J396-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J396-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K439", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K439", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K439-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K439-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSVQLPPKESALFKRVLKCYEQKQYKNGLKFCKMILSNPKFAEHGETLAMKGLTLNCLGKREEAYEFVRKGLRSDVRSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMALKLLEEFRQTQQVPPNKIDYEYSELILYQNQVMREADLFQESLEHIETYEKQICDKLLVEEIKGEMLLKLGRLKEASEVFRNLIDRNAENWCYYEGLEKALQLRSLDERLQIYEEISKQHPRAVSPRRLPLNLVPGKKFRELMDKFLRPNFSKGCPPLFTTLKSLYSNTEKVSIIQELVTNYEASLKMNGFFSPYENGEKEPPTTLLWVQYFLAQHFDKLGQYLLALEYINAVIAGTPTLIELFYIKAKIYKHIGNLKEAAKWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSKFTREGTSAMENLNEMQCMWFETECILAYQRLGRYGDALKKCHEVERHFFEITDDQFDFHTYCMRKMTLRAYVDLLRLEDTLRRHTFYFKAARSAIEIYLKLHDNPLTSESKEQDINSEVLSAKELKKMLSKQRRAQKKAKLQEDRKHTERERQQKNQKKKREEEEETASGHKEELAAEKLERVDNPLEEAIKFLIPLKTLAADNIYTHLLAFEIYFRKEKFLLMLQSVKRAFAIDSNNAWLHECLIKFSKSVSNHSNIPDIVSKVLAQEMKKIFVNKDLQRFNEDFLIHNATSLQHLLSGAKMMYFLDKSRQEKAIAIATRLDETIKDKNVKTLTKVSEALLDGSFGNCSSQYEEYRKACHNLLPLTSAFLPAVTDTALNRTIDPELLWPEI", "length": 859, "header": "tr|A0A8C2MY21-1|A0A8C2MY21_CRIGR Isoform 1 of N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X4 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"MPSVQLPPKESALFKRVLKCYEQKQYKNGLKFCKMILSNPKFAEHGETLAMKGLTLNCLGKREEAYEFVRKGLRSDVRSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMALKLLEEFRQTQQVPPNKIDYEYSELILYQNQVMREADLFQESLEHIETYEKQICDKLLVEEIKGEMLLKLGRLKEASEVFRNLIDRNAENWCYYEGLEKALQLRSLDERLQIYEEISKQHPRAVSPRRLPLNLVPGKKFRELMDKFLRPNFSKGCPPLFTTLKSLYSNTEKVSIIQELVTNYEASLKMNGFFSPYENGEKEPPTTLLWVQYFLAQHFDKLGQYLLALEYINAVIAGTPTLIELFYIKAKIYKHIGNLKEAAKWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSKFTREGTSAMENLNEMQCMWFETECILAYQRLGRYGDALKKCHEVERHFFEITDDQFDFHTYCMRKMTLRAYVDLLRLEDTLRRHTFYFKAARSAIEIYLKLHDNPLTSESKEQDINSEVLSAKELKKMLSKQRRAQKKAKLQEDRKHTERERQQKNQKKKREEEEETASGHKEELAAEKLERVDNPLEEAIKFLIPLKTLAADNIYTHLLAFEIYFRKEKFLLMLQSVKRAFAIDSNNAWLHECLIKFSKSVSNHSNIPDIVSKVLAQEMKKIFVNKDLQRFNEDFLIHNATSLQHLLSGAKMMYFLDKSRQEKAIAIATRLDETIKDKNVKTLTKVSEALLDGSFGNCSSQYEEYRKACHNLLPLTSAFLPAVTDTALNRTIDPELLWPEI", "length": 859, "header": "tr|A0A8C2MY21-1|A0A8C2MY21_CRIGR Isoform 1 of N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X4 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027258428", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258428" } ] }, { "annotation": "Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. 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Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614078.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504686", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504686" } ] }, { "annotation": "Acts as a co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY28", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY28#function" }, { "database": "UniProtKB", "id": "ARBA00053178", "url": "https://www.uniprot.org/uniprotkb/ARBA00053178#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY28", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY28" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dnajc7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY28", "locus": {} } ], "crossref": [ { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753520", "url": 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"id": "A0A8C2MY28", "url": "https://www.orthodb.org/?gene=A0A8C2MY28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45188:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45188:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504686", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504686", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MY28", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MY28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATAECDVVMAGTEPELLEDEEAKREAESFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAESDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQFVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACVACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIDDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDANNIFKAFFGGPGGFSFEASGPGNFFFQFG", "length": 494, "header": "tr|A0A8C2MY28-1|A0A8C2MY28_CRIGR Isoform 1 of DnaJ homolog subfamily C member 7 OS=Cricetulus griseus OX=10029 GN=Dnajc7 PE=4 SV=1 CANONICAL=A0A8C2MY28-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MY28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY28/entry#A0A8C2MY28-1", "sequence": { "sequence": "MAATAECDVVMAGTEPELLEDEEAKREAESFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAESDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQFVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACVACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIDDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDANNIFKAFFGGPGGFSFEASGPGNFFFQFG", "length": 494, "header": "tr|A0A8C2MY28-1|A0A8C2MY28_CRIGR Isoform 1 of DnaJ homolog subfamily C member 7 OS=Cricetulus griseus OX=10029 GN=Dnajc7 PE=4 SV=1 CANONICAL=A0A8C2MY28-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY28", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY28" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753520", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753520", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K435-1", "protein_name": "DnaJ homolog subfamily C member 7", "gene_name": "Dnajc7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MAAAAECDVIMAAPEGPGEPESEEEARREAESFKEQGNAYYAKKDYNEAYNYYTKAIDTCPNNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAASRCFQRVLELDHKNTQAQQELKNASTVLEYEKIAEVDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLALLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACLACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLEEAIDDCTNAVKLDETYIKAYLRRAQCYMDTEQYEDAVRDYEKVYQTEKTKEHKQLLKNAQMELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKARYDSGQDLEEDGLNMGDFDANNIFKAFFGGPGGFSFEASGPGNFFFQFG", "length": 496 }, "evidence": [ { "id": "A0A8C2MY28", "url": "https://omabrowser.org/oma/group/A0A8C2MY28/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q99615-1", "protein_name": "DnaJ homolog subfamily C member 7", "gene_name": "DNAJC7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAECDVVMAATEPELLDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQFG", "length": 494 }, "evidence": [ { "id": "A0A8C2MY28", "url": "https://omabrowser.org/oma/group/A0A8C2MY28/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QYI3-1", "protein_name": "DnaJ homolog subfamily C member 7", "gene_name": "Dnajc7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAATAECDVVMAATEPELLEDEDAKREAESFKEQGNAYYAKKDYNEAYNYYTKAIDMCPNNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAEVDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQFVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACVACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRQLEDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQFEEAVRDYEKVYQTEKTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDANNIFKAFFGGPGGFSFEASGPGNFYFQFG", "length": 494 }, "evidence": [ { "id": "A0A8C2MY28", "url": "https://omabrowser.org/oma/group/A0A8C2MY28/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V3W1-1", "protein_name": "Tetratricopeptide repeat protein 2, isoform A", "gene_name": "Tpr2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDDEVIEISDSEREETSSNSEMDVEITTEQPTIDVKAEQIVPKDAATIAEEKKKLGNDQYKAQNYQNALKLYTDAISLCPDSAAYYGNRAACYMMLLNYNSALTDARHAIRIDPGFEKAYVRVAKCCLALGDIIGTEQAVKMVNELNSLSTAVAAEQTAAQKLRQLEATIQANYDTKSYRNVVFYLDSALKLAPACLKYRLLKAECLAFLGRCDEALDIAVSVMKLDTTSADAIYVRGLCLYYTDNLDKGILHFERALTLDPDHYKSKQMRSKCKQLKEMKENGNMLFKSGRYREAHVIYTDALKIDEHNKDINSKLLYNRALVNTRIGNLREAVADCNRVLELNSQYLKALLLRARCYNDLEKFEESVADYETALQLEKTPEIKRMLREAKFALKKSKRKDYYKILGIGRNASDDEIKKAYRKKALVHHPDRHANSSAEERKEEELKFKEVGEAYAILSDAHKKSRYDSGQDIEEQEQADFDPNQMFRTFFQFNGGGRNNSSFNFEF", "length": 508 }, "evidence": [ { "id": "A0A8C2MY28", "url": "https://omabrowser.org/oma/group/A0A8C2MY28/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY28", "url": 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"synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 391, "end_pos": 393 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MY51-1", "uniprot_ac": "A0A8C2MY51", "uniprot_id": "A0A8C2MY51_CRIGR", "mass": { "chemical_mass": 58698.0, "monoisotopic_mass": 58698.0 }, "refseq": { "ac": "XP_027273577", "name": "solute carrier family 35 member F5 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273577" }, "gene_names": [ { "name": "Slc35f5", "type": "recommended", "evidence": [ { "id": "A0A8C2MY51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY51" } ] }, { "name": "Slc35f5", "type": "synonym", "evidence": [ { "id": "XP_027273577", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273577" } ] } ], "protein_names": [ { "name": "Solute carrier family 35 member F5", "type": "recommended", "evidence": [ { "id": "A0A8C2MY51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY51/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 35 member F5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027273577", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273577" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273577", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273577" } ] }, { "annotation": "Putative solute transporter.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY51", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY51#function" }, { "database": "UniProtKB", "id": "ARBA00037727", "url": "https://www.uniprot.org/uniprotkb/ARBA00037727#function" }, { "database": "UniProtKB", "id": "A0A9J7H058", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H058#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY51", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY51" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc35f5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY51", "locus": {} } ], "crossref": [ { "id": "100760455", "url": "https://www.ncbi.nlm.nih.gov/gene/100760455", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760455", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760455", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MY51", "url": "https://www.orthodb.org/?gene=A0A8C2MY51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23051:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23051:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00892", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00892", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273577", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273577", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MY51", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MY51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H058", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H058", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H058-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H058-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPPRLHRGAGRPGGLSSSPPFRLKSARFAVGAFEDLRDALATRLQMVCVFIMNRVNSQNSGFSQRRRMALGIVILLLVDVIWVASSELTSYVFTQYNKPFFSTFAKTSMFVLYLLGFIIWKPWRQQCTRGFRGKPAAFFADAEGYFAACTTDTSMSSSLSEPLYVPVKFHDLPSEKLESTNIGTEKIPKKSRVRFSNIMEIRQLPSSHALEAKLSRMSYPTVKDQESILKTVGKLTATQVAKISFFFCFVWFLANLSYQEALSDTQVAIVNILSSTSGLFTLILAAVFPSNSGDRFTLSKLLAVILSIGGVVLVNLSGSEKSAGRDTIGSIWSLAGAMLYAVYIVMIKRKVDREDKLDIPMFFGFVGLFNLLLLWPGFFLLHYTGFEDFEFPNKVVLLCILINGLIGTVLSEFLWLWGCFLTSSLIGTLALSLTIPLSIIADMCMQKVQFSWLFFAGAIPVFFSFFIVTLLCHYNNWDPVMVGVRRIFAFICRKHRIQRVPEDSEQCESLIPMHSVSQEDGAT", "length": 524, "header": "tr|A0A8C2MY51-1|A0A8C2MY51_CRIGR Isoform 1 of Solute carrier family 35 member F5 OS=Cricetulus griseus OX=10029 GN=Slc35f5 PE=3 SV=1 CANONICAL=A0A8C2MY51-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MY51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY51/entry#A0A8C2MY51-1", "sequence": { "sequence": "MVPPRLHRGAGRPGGLSSSPPFRLKSARFAVGAFEDLRDALATRLQMVCVFIMNRVNSQNSGFSQRRRMALGIVILLLVDVIWVASSELTSYVFTQYNKPFFSTFAKTSMFVLYLLGFIIWKPWRQQCTRGFRGKPAAFFADAEGYFAACTTDTSMSSSLSEPLYVPVKFHDLPSEKLESTNIGTEKIPKKSRVRFSNIMEIRQLPSSHALEAKLSRMSYPTVKDQESILKTVGKLTATQVAKISFFFCFVWFLANLSYQEALSDTQVAIVNILSSTSGLFTLILAAVFPSNSGDRFTLSKLLAVILSIGGVVLVNLSGSEKSAGRDTIGSIWSLAGAMLYAVYIVMIKRKVDREDKLDIPMFFGFVGLFNLLLLWPGFFLLHYTGFEDFEFPNKVVLLCILINGLIGTVLSEFLWLWGCFLTSSLIGTLALSLTIPLSIIADMCMQKVQFSWLFFAGAIPVFFSFFIVTLLCHYNNWDPVMVGVRRIFAFICRKHRIQRVPEDSEQCESLIPMHSVSQEDGAT", "length": 524, "header": "tr|A0A8C2MY51-1|A0A8C2MY51_CRIGR Isoform 1 of Solute carrier family 35 member F5 OS=Cricetulus griseus OX=10029 GN=Slc35f5 PE=3 SV=1 CANONICAL=A0A8C2MY51-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H058-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY51/entry#A0A9J7H058-1", "sequence": { "sequence": "MVCVFIMNRVNSQNSGFSQRRRMALGIVILLLVDVIWVASSELTSYVFTQYNKPFFSTFAKTSMFVLYLLGFIIWKPWRQQCTRGFRGKPAAFFADAEGYFAACTTDTSMSSSLSEPLYVPVKFHDLPSEKLESTNIGTEKIPKKSRVRFSNIMEIRQLPSSHALEAKLSRMSYPTVKDQESILKTVGKLTATQVAKISFFFCFVWFLANLSYQEALSDTQVAIVNILSSTSGLFTLILAAVFPSNSGDRFTLSKLLAVILSIGGVVLVNLSGSEKSAGRDTIGSIWSLAGAMLYAVYIVMIKRKVDREDKLDIPMFFGFVGLFNLLLLWPGFFLLHYTGFEDFEFPNKVVLLCILINGLIGTVLSEFLWLWGCFLTSSLIGTLALSLTIPLSIIADMCMQKVQFSWLFFAGAIPVFFSFFIVTLLCHYNNWDPVMVGVRRIFAFICRKHRIQRVPEDSEQCESLIPMHSVSQEDGAT", "length": 478, "header": "tr|A0A9J7H058-1|A0A9J7H058_CRIGR Computationally mapped isoform of Solute carrier family 35 member F5 OS=Cricetulus griseus OX=10029 GN=Slc35f5 PE=3 SV=1 CANONICAL=A0A8C2MY51-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY51", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY51" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY51", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY51" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760455", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760455", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY51", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY51" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "choline transmembrane transporter activity", "id": "GO:0015220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015220", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY51", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MY51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY51" }, { "id": "PF00892", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00892" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EamA", "eco_id": "ECO_0000259", "start_pos": 329, "end_pos": 470, "start_aa": "Ile", "end_aa": "Thr", "glycosite_overlap": "" } ], 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griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304357", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304357" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY65" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rimklb", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY65", "locus": {} } ], "crossref": [ { "id": "100760031", "url": "https://www.ncbi.nlm.nih.gov/gene/100760031", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760031", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760031", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DAAYNFN", "url": "https://omabrowser.org/oma/group/DAAYNFN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MY65", "url": "https://www.orthodb.org/?gene=A0A8C2MY65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21621", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21621", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21621:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21621:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304357", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304357", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "40035", "url": "https://www.rhea-db.org/rhea/40035", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MY65", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MY65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY65-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCSSVAAKLWFLTDRRIREDYPQKEILRALKAKCCEEELDFRAVVMDEVVLTIEQGNLGLRINGELISAYPQVVVVRVPTPWVQSDSDITVLRHLEKMGCRLMNRPQAILNCVNKFWTFQELAGHGVPLPDTFSYGGHENFAKMIDEAEVLEFPMVVKNTRGHRGKAVFLARDKHHLADLSHLIRHEAPYLFQKYIKESHGRDVRVIVVGGRVVGTMLRCSTDGRMQSNCSLGGVGMMCSLSEQGKQLAIQVSNILGMDVCGIDLLMKDDGSFCVCEANANVGFIAFDKACNLDVAGIIADYAASLLPAGRLTRRMSLLSVVSTASETSEPELGPPASTAVDNMSASSSSVDSDPESTTERELLTKLPGGLFNMNQLLANEIKLLVE", "length": 387, "header": "tr|A0A8C2MY65-1|A0A8C2MY65_CRIGR Isoform 1 of N-acetylaspartylglutamate synthase OS=Cricetulus griseus OX=10029 GN=Rimklb PE=3 SV=1 CANONICAL=A0A8C2MY65-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MY65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY65/entry#A0A8C2MY65-1", "sequence": { "sequence": "MCSSVAAKLWFLTDRRIREDYPQKEILRALKAKCCEEELDFRAVVMDEVVLTIEQGNLGLRINGELISAYPQVVVVRVPTPWVQSDSDITVLRHLEKMGCRLMNRPQAILNCVNKFWTFQELAGHGVPLPDTFSYGGHENFAKMIDEAEVLEFPMVVKNTRGHRGKAVFLARDKHHLADLSHLIRHEAPYLFQKYIKESHGRDVRVIVVGGRVVGTMLRCSTDGRMQSNCSLGGVGMMCSLSEQGKQLAIQVSNILGMDVCGIDLLMKDDGSFCVCEANANVGFIAFDKACNLDVAGIIADYAASLLPAGRLTRRMSLLSVVSTASETSEPELGPPASTAVDNMSASSSSVDSDPESTTERELLTKLPGGLFNMNQLLANEIKLLVE", "length": 387, "header": "tr|A0A8C2MY65-1|A0A8C2MY65_CRIGR Isoform 1 of N-acetylaspartylglutamate synthase OS=Cricetulus griseus OX=10029 GN=Rimklb PE=3 SV=1 CANONICAL=A0A8C2MY65-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MY88-1", "uniprot_ac": "A0A8C2MY88", "uniprot_id": "A0A8C2MY88_CRIGR", "mass": { "chemical_mass": 86232.0, "monoisotopic_mass": 86232.0 }, "refseq": { "ac": "XP_007607175", "name": "C-Maf-inducing protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007607175" }, "gene_names": [ { "name": "Cmip", "type": "recommended", "evidence": [ { "id": "A0A8C2MY88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY88" } ] }, { "name": "Cmip", "type": "synonym", "evidence": [ { "id": "XP_007607175", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007607175" } ] } ], "protein_names": [ { "name": "C-Maf-inducing protein", "type": "recommended", "evidence": [ { "id": "A0A8C2MY88", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NW_003613583.1) and transcript sequence (IACG01088631.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007607175.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007607175", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007607175" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY88", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY88" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cmip", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY88", "locus": {} } ], "crossref": [ { "id": "cd00821", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00821", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759767", "url": "https://www.ncbi.nlm.nih.gov/gene/100759767", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032675", "url": 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"MDVTSSSGGGDPRQIEETKPLLGSDVSGPEGTKVMGAVPCRRALLLCNGMRYKLLQEGDIQVCVIRHPRTFLSKILTSKFLRRWEPHHLTLADNSLASATPSGYMENSVSYSAIEDVQPLSWENAPKYCLQLTIPGGTVLLQAANSYLRDQWFHSLQWKKKIYKYKKVLSNPSRWEVVLKEIRTLVDMALTSPLQDDSINQAPLEIVSKLLSENTNLTTQEHESIIVAIAPLLENNHPPPDLCEFFCKHCRERPRSMVVIEVFTPVVQRILKHNMDFGKCPRLRLFTQEYILALNELNAGMEVVKKFIQSMHGPTGHCPHPRVLPNLVAVCLAAIYSCYEEFINSRDNSPSLKEIRNGCQQPCDRKPTLPLRLLHPSPDLVSQEATLSEPRLKSVVVASSEVHVEVERTSTAKPALTASTGNDSEPNLIDCLMVSPACGTMSIELGPQAGRTLGCHVEILKLLSDYDDWRPSLASLLQPIPFPKEALAHEKFTKELKYVIQRFAEDPRQEVHSCLLSVRAGKDGWFQLYSPGGVACDDDGELFASMVHILMGSCYKTKKFLLSLAENKLGPCMLLALRGNQTMAEILCLMLEYNIIDNNDTQLQIISTLESTDVGKRMYEQLCDRQRELKELQRKGGPTRLTLPSKSTDADLARLLSSGSFGNLENLSLAFTNVTSACAEHLIKLPSLKQLNLWSTQFGDAGLRLLSEHLTMLQVLNLCETPVTDAGLLALSSMKSLCSLNMNSTKLSADTYEDLKAKLPNLKEVDVRYTEAW", "length": 773, "header": "tr|A0A8C2MY88-1|A0A8C2MY88_CRIGR Isoform 1 of C-Maf-inducing protein OS=Cricetulus griseus OX=10029 GN=Cmip PE=4 SV=1 CANONICAL=A0A8C2MY88-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MY88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY88/entry#A0A8C2MY88-1", "sequence": { "sequence": "MDVTSSSGGGDPRQIEETKPLLGSDVSGPEGTKVMGAVPCRRALLLCNGMRYKLLQEGDIQVCVIRHPRTFLSKILTSKFLRRWEPHHLTLADNSLASATPSGYMENSVSYSAIEDVQPLSWENAPKYCLQLTIPGGTVLLQAANSYLRDQWFHSLQWKKKIYKYKKVLSNPSRWEVVLKEIRTLVDMALTSPLQDDSINQAPLEIVSKLLSENTNLTTQEHESIIVAIAPLLENNHPPPDLCEFFCKHCRERPRSMVVIEVFTPVVQRILKHNMDFGKCPRLRLFTQEYILALNELNAGMEVVKKFIQSMHGPTGHCPHPRVLPNLVAVCLAAIYSCYEEFINSRDNSPSLKEIRNGCQQPCDRKPTLPLRLLHPSPDLVSQEATLSEPRLKSVVVASSEVHVEVERTSTAKPALTASTGNDSEPNLIDCLMVSPACGTMSIELGPQAGRTLGCHVEILKLLSDYDDWRPSLASLLQPIPFPKEALAHEKFTKELKYVIQRFAEDPRQEVHSCLLSVRAGKDGWFQLYSPGGVACDDDGELFASMVHILMGSCYKTKKFLLSLAENKLGPCMLLALRGNQTMAEILCLMLEYNIIDNNDTQLQIISTLESTDVGKRMYEQLCDRQRELKELQRKGGPTRLTLPSKSTDADLARLLSSGSFGNLENLSLAFTNVTSACAEHLIKLPSLKQLNLWSTQFGDAGLRLLSEHLTMLQVLNLCETPVTDAGLLALSSMKSLCSLNMNSTKLSADTYEDLKAKLPNLKEVDVRYTEAW", "length": 773, "header": "tr|A0A8C2MY88-1|A0A8C2MY88_CRIGR Isoform 1 of C-Maf-inducing protein OS=Cricetulus griseus OX=10029 GN=Cmip PE=4 SV=1 CANONICAL=A0A8C2MY88-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JF67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY88/entry#A0A9J7JF67-1", "sequence": { "sequence": "MDVTSSSGGGDPRQIEETKPLLGSDVSGPEGTKVMGAVPCRRALLLCNGMRYKLLQEGDIQVCVIRHPRTFLSKILTSKFLRRWEPHHLTLADNSLASATPSGYMENSVSYSAIEDVQPLSWENAPKYCLQLTIPGGTVLLQAANSYLRDQWFHSLQWKKKIYKYKKVLSNPSRWEVVLKEIRTLVDMALTSPLQDDSINQAPLEIVSKLLSENTNLTTQEHESIIVAIAPLLENNHPPPDLCEFFCKHCRERPRSMVVIEVFTPVVQRILKHNMDFGKCPRLRLFTQEYILALNELNAGMEVVKKFIQSMHGPTGHCPHPRVLPNLVAVCLAAIYSCYEEFINSRDNSPSLKEIRNGCQQPCDRKPTLPLRLLHPSPDLVSQEATLSEPRLKSVVVASSEVHVEVERTSTAKPALTASTGNDSEPNLIDCLMVSPACGTMSIELGPQAGRTLGCHVEILKLLSDYDDWRPSLASLLQPIPFPKEALAHEKFTKELKYVIQRFAEDPRQEVHSCLLSVRAGKDGWFQLYSPGGVACDDDGELFASMVHILMGSCYKTKKFLLSLAENKLGPCMLLALRGNQTMAEILCLMLEYNIIDNNDTQLQIISTLESTDVGKRMYEQLCDRQRELKELQRKGGPTRLTLPSKSTFGDAGLRLLSEHLTMLQVLNLCETPVTDAGLLALSSMKSLCSLNMNSTKLSADTYEDLKAKLPNLKEVDVRYTEAW", "length": 724, "header": "tr|A0A9J7JF67-1|A0A9J7JF67_CRIGR Computationally mapped isoform of C-Maf-inducing protein isoform X3 OS=Cricetulus griseus OX=10029 GN=Cmip PE=4 SV=1 CANONICAL=A0A8C2MY88-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 100, "start_aa": "Thr", "end_pos": 100, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr100", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY88", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY88" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY88", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY88" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759767", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759767", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY88", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY88" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY88", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY88" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 580, "end_pos": 582, "annotation": "n_glycosylation_sequon" }, { "start_pos": 599, "end_pos": 601, "annotation": "n_glycosylation_sequon" }, { "start_pos": 666, "end_pos": 668, "annotation": "n_glycosylation_sequon" }, { "start_pos": 673, "end_pos": 675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 743, "end_pos": 745, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MY88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY88" }, { "id": "PF23066", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23066" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-Maf-inducing protein PH", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 169, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 100 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 216, "end_pos": 218 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 580, "end_pos": 582 }, { "start_pos": 599, "end_pos": 601 }, { "start_pos": 666, "end_pos": 668 }, { "start_pos": 673, "end_pos": 675 }, { "start_pos": 743, "end_pos": 745 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { 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"count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MY97-1", "uniprot_ac": "A0A8C2MY97", "uniprot_id": "A0A8C2MY97_CRIGR", "mass": { "chemical_mass": 114530.0, "monoisotopic_mass": 114530.0 }, "refseq": { "ac": "XP_035299094", "name": "rho guanine nucleotide exchange factor 18 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299094" }, "gene_names": [ { "name": "Arhgef18", "type": "recommended", "evidence": [ { "id": "A0A8C2MY97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY97" } ] }, { "name": "Arhgef18", "type": "synonym", "evidence": [ { "id": "XP_035299094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299094" } ] } ], "protein_names": [ { "name": "Rho guanine nucleotide exchange factor 18 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2MY97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY97/entry#names_and_taxonomy" } ] }, { "name": "rho guanine nucleotide exchange factor 18 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035299094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299094" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035299094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299094" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY97" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Arhgef18", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY97", "locus": {} } ], "crossref": [ { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15794", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15794", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770929", "url": "https://www.ncbi.nlm.nih.gov/gene/100770929", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770929", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770929", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MY97", "url": "https://www.orthodb.org/?gene=A0A8C2MY97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GZH0", "url": "https://www.orthodb.org/?gene=A0A9J7GZH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47440", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47440", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47440:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47440:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17838", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17838", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035299094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299094", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MY97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MY97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYY6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVSQKGGPQSAPSPAGSGVRLGPVAGDMDEADSVFLKLKQTADDSLSLTSSNAESVFIEDPYIASLRCEIESDAHEFEAESWSLSVDLAYAKKQKKEVVKRQDVLYELMQTEAHHVRTLKIMLKVYSRALQEELQFSGPAISRLFPCADDLLEMHSHFLARLKERRQEFLEEGSDRNYVIQKIGDVLVQQFSGETGERMKEKYGVFCSGHNDAVSHYKLLLQQSKKFQNLIKKIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGTEDYKDLSQALNLIKDIISQVDARVSEYEKGQRLREIAGKVDLKSSSKLKNGLTFRKEDMLQRQLHLEGTLCWKSTSGRLKDVLAVLLTDVLLLLQEKDQRYVFASVDSKPPVISLQKLIVREVANEEKAMFLISASMQGPEMYEIYTSSKEDRNTWMAHIRRAVESCPDEEEGPFSETEERKMTEARTMRLRDFQERLSLKDQMIAQSLLEKQQIYLEMAELSGLEESAHCRGLFRGGGDPSETLRGEQILRSAMSEIEGIQSLICRQLGSTSGQVEEGGVSAGLPRRAETFGGYDSVGSPSKSGSFKKKMCSNDLRPQDWQGPSGSPDSKPCDSPTPSGCEESPQTVEMPSAESSSCLPTVLESELVHRVQTLSQLLLSLQAVIAQQDSYVEMQRVAIQEREKQFRLQSTRGNLLLEQERQRNFEKQREERAGVEKLQSQLRQEQQRWERERARQQQELELAGARLQEREGEARQLRERLDQERTELERQRQAYQHDLERLREAQRAVDRERERLELLRRFKKQNTVPGALPPEVLAEAQPTSHPPSFNGDGLEGRLALAKTPGTQGSMLLPGTGPEYIERPEVARWDSVPAESRTAKSDVPIQLLSATNQIQRQTAVQQQIPTKLAASTKGGKDKGSKSRGSQRWESSASFDLKQQLLLNKFISKDENSSRNRRSLSPILPATHGSAPVPDPCLPSPAPAATSPEAFFKSGSTSLPPASPSPSLPTTPLTAKDEVGKEDVIFF", "length": 1020, "header": "tr|A0A8C2MY97-1|A0A8C2MY97_CRIGR Isoform 1 of Rho guanine nucleotide exchange factor 18 isoform X2 OS=Cricetulus griseus OX=10029 GN=Arhgef18 PE=4 SV=1 CANONICAL=A0A8C2MY97-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MY97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY97/entry#A0A8C2MY97-1", "sequence": { "sequence": "MTVSQKGGPQSAPSPAGSGVRLGPVAGDMDEADSVFLKLKQTADDSLSLTSSNAESVFIEDPYIASLRCEIESDAHEFEAESWSLSVDLAYAKKQKKEVVKRQDVLYELMQTEAHHVRTLKIMLKVYSRALQEELQFSGPAISRLFPCADDLLEMHSHFLARLKERRQEFLEEGSDRNYVIQKIGDVLVQQFSGETGERMKEKYGVFCSGHNDAVSHYKLLLQQSKKFQNLIKKIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGTEDYKDLSQALNLIKDIISQVDARVSEYEKGQRLREIAGKVDLKSSSKLKNGLTFRKEDMLQRQLHLEGTLCWKSTSGRLKDVLAVLLTDVLLLLQEKDQRYVFASVDSKPPVISLQKLIVREVANEEKAMFLISASMQGPEMYEIYTSSKEDRNTWMAHIRRAVESCPDEEEGPFSETEERKMTEARTMRLRDFQERLSLKDQMIAQSLLEKQQIYLEMAELSGLEESAHCRGLFRGGGDPSETLRGEQILRSAMSEIEGIQSLICRQLGSTSGQVEEGGVSAGLPRRAETFGGYDSVGSPSKSGSFKKKMCSNDLRPQDWQGPSGSPDSKPCDSPTPSGCEESPQTVEMPSAESSSCLPTVLESELVHRVQTLSQLLLSLQAVIAQQDSYVEMQRVAIQEREKQFRLQSTRGNLLLEQERQRNFEKQREERAGVEKLQSQLRQEQQRWERERARQQQELELAGARLQEREGEARQLRERLDQERTELERQRQAYQHDLERLREAQRAVDRERERLELLRRFKKQNTVPGALPPEVLAEAQPTSHPPSFNGDGLEGRLALAKTPGTQGSMLLPGTGPEYIERPEVARWDSVPAESRTAKSDVPIQLLSATNQIQRQTAVQQQIPTKLAASTKGGKDKGSKSRGSQRWESSASFDLKQQLLLNKFISKDENSSRNRRSLSPILPATHGSAPVPDPCLPSPAPAATSPEAFFKSGSTSLPPASPSPSLPTTPLTAKDEVGKEDVIFF", "length": 1020, "header": "tr|A0A8C2MY97-1|A0A8C2MY97_CRIGR Isoform 1 of Rho guanine nucleotide exchange factor 18 isoform X2 OS=Cricetulus griseus OX=10029 GN=Arhgef18 PE=4 SV=1 CANONICAL=A0A8C2MY97-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GYY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY97/entry#A0A9J7GYY6-1", "sequence": { "sequence": "MDEADSVFLKLKQTADDSLSLTSSNAESVFIEDPYIASLRCEIESDAHEFEAESWSLSVDLAYAKKQKKEVVKRQDVLYELMQTEAHHVRTLKIMLKVYSRALQEELQFSGPAISRLFPCADDLLEMHSHFLARLKERRQEFLEEGSDRNYVIQKIGDVLVQQFSGETGERMKEKYGVFCSGHNDAVSHYKLLLQQSKKFQNLIKKIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGTEDYKDLSQALNLIKDIISQVDARVSEYEKGQRLREIAGKVDLKSSSKLKNGLTFRKEDMLQRQLHLEGTLCWKSTSGRLKDVLAVLLTDVLLLLQEKDQRYVFASVDSKPPVISLQKLIVREVANEEKAMFLISASMQGPEMYEIYTSSKEDRNTWMAHIRRAVESCPDEEEGPFSETEERKMTEARTMRLRDFQERLSLKDQMIAQSLLEKQQIYLEMAELSGLEESAHCRGLFRGGGDPSETLRGEQILRSAMSEIEGIQSLICRQLGSTSGQVEEGGVSAGLPRRAETFGGYDSVGSPSKSGSFKKKMCSNDLRPQDWQGPSGSPDSKPCDSPTPSGCEESPQTVEMPSAESSSCLPTVLESELVHRVQTLSQLLLSLQAVIAQQDSYVEMQRVAIQEREKQFRLQSTRGNLLLEQERQRNFEKQREERAGVEKLQSQLRQEQQRWERERARQQQELELAGARLQEREGEARQLRERLDQERTELERQRQAYQHDLERLREAQRAVDRERERLELLRRFKKQNTVPGALPPEVLAEAQPTSHPPSFNGDGLEGRLALAKTPGTQGSMLLPGTGPEYIERPEVARWDSVPAESRTAKSDVPIQLLSATNQIQRQTAVQQQIPTKLAASTKGGKDKGSKSRGSQRWESSASFDLKQQLLLNKFISKDENSSRNRRSLSPILPATHGSAPVPDPCLPSPAPAATSPEAFFKSGSTSLPPASPSPSLPTTPLTAKDEVGKEDVIFF", "length": 992, "header": "tr|A0A9J7GYY6-1|A0A9J7GYY6_CRIGR Computationally mapped isoform of Rho guanine nucleotide exchange factor 18 isoform X3 OS=Cricetulus griseus OX=10029 GN=Arhgef18 PE=4 SV=1 CANONICAL=A0A8C2MY97-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY97/entry#A0A9J7GZH0-1", "sequence": { "sequence": "MEKAQWQECSEPKPCAQPLDSGDAASASKGSRGLWKPENPDFFSPMEDDQADALPRHLSESTEDLSLDMGALQGSEYLRDLGLGAPSDHHQSEVAVDPETPRKEVRRETLCSSDAVNPALPQRRSWERPRSCSEGCRRLSLDASTVDEGACLPRTLASLALNLSGEGQKSWTQVCLPDSEIPEEPSSKECSSPEKRLRSKSVPVSCEEISCLELASGSDESPAPVQGLEPPVLECLEKDHVEPDHVLIVQQVLQELRQYHGARQRAHKSTSPVGAHSSLTWFEFLSESEDGAGKNEKTDRSTRVKRSLSSLRSRVTRQKEKGKSPAHLKDKLQDSPGRRECVNGHQLVRGTFVGYSNCPLCGKPLLSSVLRPGWPRSRYLQGVSQVSSGFXXLYSLXDSIILQCSPRVHIGVPNSSFFFMFVCTCSCMYDKRQPXRPSSCVIPSCFTCDVCTGTSMDLYTHVFTYVQRLVINSGYFPPSLSII", "length": 483, "header": "tr|A0A9J7GZH0-1|A0A9J7GZH0_CRIGR Computationally mapped isoform of LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 18 isoform X4 OS=Cricetulus griseus OX=10029 GN=Arhgef18 PE=4 SV=1 CANONICAL=A0A8C2MY97-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 612, "start_aa": "Thr", "end_pos": 612, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr612", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY97" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY97" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770929", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770929", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein localization to cell-cell junction", "id": "GO:0150105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150105", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY97" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY97" } ], "pmid": "" }, { "name": "negative regulation of stress fiber assembly", "id": "GO:0051497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051497", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY97" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY97" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MY97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY97" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYC2/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 20", "type": "synonym", "evidence": [ { "id": "XP_003497710", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497710" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613658.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497710", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497710" } ] }, { "annotation": "Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response and anterograde Golgi to endosome transport. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis. The BCR(KLHL20) E3 ubiquitin ligase complex also specifically mediates 'Lys-33'-linked ubiquitination. Involved in anterograde Golgi to endosome transport by mediating 'Lys-33'-linked ubiquitination of CORO7, promoting interaction between CORO7 and EPS15, thereby facilitating actin polymerization and post-Golgi trafficking. Also acts as a regulator of endothelial migration during angiogenesis by controlling the activation of Rho GTPases. The BCR(KLHL20) E3 ubiquitin ligase complex acts as a regulator of neurite outgrowth by mediating ubiquitination and degradation of PDZ-RhoGEF/ARHGEF11.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYC2#function" }, { "database": "UniProtKB", "id": "ARBA00059030", "url": "https://www.uniprot.org/uniprotkb/ARBA00059030#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYC2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Klhl20", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYC2", "locus": {} } ], "crossref": [ { "id": "cd18249", "url": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003497710", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497710", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MYC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MYC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYC2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGKPMRRCTNIRPGETGMDVTSRCTLGDPNKLPEGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGFLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW", "length": 609, "header": "tr|A0A8C2MYC2-1|A0A8C2MYC2_CRIGR Isoform 1 of Kelch-like protein 20 OS=Cricetulus griseus OX=10029 GN=Klhl20 PE=4 SV=1 CANONICAL=A0A8C2MYC2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MYC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYC2/entry#A0A8C2MYC2-1", "sequence": { "sequence": "MEGKPMRRCTNIRPGETGMDVTSRCTLGDPNKLPEGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGFLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW", "length": 609, "header": "tr|A0A8C2MYC2-1|A0A8C2MYC2_CRIGR Isoform 1 of Kelch-like protein 20 OS=Cricetulus griseus OX=10029 GN=Klhl20 PE=4 SV=1 CANONICAL=A0A8C2MYC2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYC2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYC2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774070", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774070", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYC2" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYC2", "url": 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"uniprot_id": "A0A8C2MYE3_CRIGR", "mass": { "chemical_mass": 25776.0, "monoisotopic_mass": 25776.0 }, "refseq": { "ac": "XP_027254401", "name": "ubiquitin-conjugating enzyme E2 J2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254401" }, "gene_names": [ { "name": "Ube2j2", "type": "recommended", "evidence": [ { "id": "A0A8C2MYE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE3" } ] }, { "name": "Ube2j2", "type": "synonym", "evidence": [ { "id": "XP_027254401", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254401" } ] } ], "protein_names": [ { "name": "Ubiquitin-conjugating enzyme E2 J2", "type": "recommended", "evidence": [ { "id": "A0A8C2MYE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE3/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.23", "type": "synonym", "evidence": [ { "id": "A0A8C2MYE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE3/entry#names_and_taxonomy" } ] }, { "name": "Non-canonical ubiquitin-conjugating enzyme 2", "type": "synonym", "evidence": [ { "id": "A0A8C2MYE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE3/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-conjugating enzyme E2 J2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027254401", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254401" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027254401", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254401" } ] }, { "annotation": "Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD). In cooperation with the GATOR2 complex, catalyzes 'Lys-6'-linked ubiquitination of NPRL2.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE3#function" }, { "database": "UniProtKB", "id": "ARBA00054775", "url": "https://www.uniprot.org/uniprotkb/ARBA00054775#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ube2j2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE3", "locus": {} } ], "crossref": [ { "id": "cd23799", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23799", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768172", "url": "https://www.ncbi.nlm.nih.gov/gene/100768172", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GWSVATI", "url": "https://omabrowser.org/oma/group/GWSVATI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24067", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24067", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027254401", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254401", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MYE3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MYE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSNSNKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTEIKQKQKAQDELSSRPQNLPLPDVVPDGEMHRGQNGLQLLNGHAPAAGPNLGGLPQANRHHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE", "length": 232, "header": "tr|A0A8C2MYE3-1|A0A8C2MYE3_CRIGR Isoform 1 of Ubiquitin-conjugating enzyme E2 J2 OS=Cricetulus griseus OX=10029 GN=Ube2j2 PE=4 SV=1 CANONICAL=A0A8C2MYE3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MYE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE3/entry#A0A8C2MYE3-1", "sequence": { "sequence": "MSSNSNKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTEIKQKQKAQDELSSRPQNLPLPDVVPDGEMHRGQNGLQLLNGHAPAAGPNLGGLPQANRHHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE", "length": 232, "header": "tr|A0A8C2MYE3-1|A0A8C2MYE3_CRIGR Isoform 1 of Ubiquitin-conjugating enzyme E2 J2 OS=Cricetulus griseus OX=10029 GN=Ube2j2 PE=4 SV=1 CANONICAL=A0A8C2MYE3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K8C5-1", "protein_name": "Ubiquitin-conjugating enzyme E2 J2", "gene_name": "Ube2j2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHQAKALDSARKMSSNSNKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKKQLAAQSLVFNLKDKVFCELFPEVVEEIKQKQKAQDELSNRPQNLPLPDVVPDGEMHRGQNGIQLLNGHAPAAGPNLAGLPQANRHHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE", "length": 271 }, "evidence": [ { "id": "A0A8C2MYE3", "url": "https://omabrowser.org/oma/group/A0A8C2MYE3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A4X1W8Z8-1", "protein_name": "Ubiquitin-conjugating enzyme E2 J2", "gene_name": "UBE2J2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSSSGKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKRQLAAQSLVFNLKDKVFCELFPEVVEEIKQKQKAQDELSSRPQALPLPDVVPDGETHHGQNGLPILNGHAPGAGPHLAGLQQANRHHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE", "length": 259 }, "evidence": [ { "id": "A0A8C2MYE3", "url": "https://omabrowser.org/oma/group/A0A8C2MYE3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P33296-1", "protein_name": "Ubiquitin-conjugating enzyme E2 6", "gene_name": "UBC6", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MATKQAHKRLTKEYKLMVENPPPYILARPNEDNILEWHYIITGPADTPYKGGQYHGTLTFPSDYPYKPPAIRMITPNGRFKPNTRLCLSMSDYHPDTWNPGWSVSTILNGLLSFMTSDEATTGSITTSDHQKKTLARNSISYNTFQNVRFKLIFPEVVQENVETLEKRKLDEGDAANTGDETEDPFTKAAKEKVISLEEILDPEDRIRAEQALRQSENNSKKDGKEPNDSSSMVYIGIAIFLFLVGLFMK", "length": 250 }, "evidence": [ { "id": "A0A8C2MYE3", "url": "https://omabrowser.org/oma/group/A0A8C2MYE3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q2TA03-1", "protein_name": "Ubiquitin-conjugating enzyme E2 J2", "gene_name": "UBE2J2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSNSVKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKRQLAAQSLVFNLKDKVFCELFPEVVEEIKQKQKAQDELSSRPQALPLPDVVPDGETHHGQHGLPLLNGHAPGAGPHLAGLQQANRHHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE", "length": 259 }, "evidence": [ { "id": "A0A8C2MYE3", "url": "https://omabrowser.org/oma/group/A0A8C2MYE3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54AK6-1", "protein_name": "Ubiquitin-conjugating enzyme E2 J2-like", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSEHNSDIVHPPTKDCITRLKREFQEISKNPIENILVTPSPSNILEWHYVILGASNTPYEGGVYYGQLIFKYNYPLSPPSILMTTPSGRFETQKRLCLSISDYHPESWSPSWSTSSILLGLLSFMSDNEVTAGSIVTTNDEKRILATKSMDFNKKNKTFCELFPYLAMDE", "length": 170 }, "evidence": [ { "id": "A0A8C2MYE3", "url": "https://omabrowser.org/oma/group/A0A8C2MYE3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6P073-1", "protein_name": "Ubiquitin-conjugating enzyme E2 J2", "gene_name": "Ube2j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNNSNKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKKQLAAQSLVFNLKDKVFCELFPEVVEEIKQKQKAQDELSNRPQNLPLPDVVPDGELHRGQHGIQLLNGHAPAAGPNLAGLPQANRHHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE", "length": 259 }, "evidence": [ { "id": "A0A8C2MYE3", "url": "https://omabrowser.org/oma/group/A0A8C2MYE3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N2K1-1", "protein_name": "Ubiquitin-conjugating enzyme E2 J2", "gene_name": "UBE2J2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVVEEIKQKQKAQDELSSRPQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANRHHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE", "length": 259 }, "evidence": [ { "id": "A0A8C2MYE3", "url": "https://omabrowser.org/oma/group/A0A8C2MYE3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE3" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYE3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYE3" } ], "pmid": "" } ] } ] }, 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gap :: added 69 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613852.1) and transcript sequence (JI884090.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007640366", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640366" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYN5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYN5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Jpt2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYN5", "locus": {} } ], "crossref": [ { "id": "100765136", "url": "https://www.ncbi.nlm.nih.gov/gene/100765136", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033335", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033335", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765136", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765136", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MYN5", "url": "https://www.orthodb.org/?gene=A0A8C2MYN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34930", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34930", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34930:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34930:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_007640366", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640366", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MYN5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MYN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAV6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFQGADGQAGGSGSRAMKPPGGESSNLFGTPEEGIPSSKPNRMASNIFGPTEEPKNIPKRTNPPGGKGSGIFDESTPVQTRQRLNPPGGKTSDIFGSPVTATAPLAHPNKPKDHVLLCEGEDSKSDLNATTNSTPKGEQSEKGSSKEADHAKIPEPTPTVDSHEPRLGPRPRSHNKVLNPPGGKSSISFY", "length": 190, "header": "tr|A0A8C2MYN5-1|A0A8C2MYN5_CRIGR Isoform 1 of Jupiter microtubule associated homolog 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Jpt2 PE=3 SV=1 CANONICAL=A0A8C2MYN5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MYN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYN5/entry#A0A8C2MYN5-1", "sequence": { "sequence": "MFQGADGQAGGSGSRAMKPPGGESSNLFGTPEEGIPSSKPNRMASNIFGPTEEPKNIPKRTNPPGGKGSGIFDESTPVQTRQRLNPPGGKTSDIFGSPVTATAPLAHPNKPKDHVLLCEGEDSKSDLNATTNSTPKGEQSEKGSSKEADHAKIPEPTPTVDSHEPRLGPRPRSHNKVLNPPGGKSSISFY", "length": 190, "header": "tr|A0A8C2MYN5-1|A0A8C2MYN5_CRIGR Isoform 1 of Jupiter microtubule associated homolog 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Jpt2 PE=3 SV=1 CANONICAL=A0A8C2MYN5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYN5/entry#A0A9J7GAV6-1", "sequence": { "sequence": "MRAMKPPGGESSNLFGTPEEGIPSSKPNRMASNIFGPTEEPKNIPKRTNPPGGKGSGIFDESTPVQTRQRLNPPGGKTSDIFGSPVTATAPLAHPNKPKDHVLLCEGEDSKSDLNATTNSTPKGEQSEKGSSKEADHAKIPEPTPTVDSHEPRLGPRPRSHNKVLNPPGGKSSISFY", "length": 177, "header": "tr|A0A9J7GAV6-1|A0A8C2MYN5_CRIGR Computationally mapped isoform of Jupiter microtubule associated homolog 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Jpt2 PE=3 SV=1 CANONICAL=A0A8C2MYN5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 157, "start_aa": "Thr", "end_pos": 157, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr157", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765136", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765136", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYN5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYN5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYN5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYN5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYN5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYN5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of calcium-mediated signaling", "id": "GO:0050848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050848", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYN5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYN5" } ], "pmid": "" }, { "name": "endocytosis involved in viral entry into host cell", "id": "GO:0075509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075509", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYN5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 157 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 132, "end_pos": 134 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MYR0-1", "uniprot_ac": "A0A8C2MYR0", "uniprot_id": "A0A8C2MYR0_CRIGR", "mass": { "chemical_mass": 83204.0, "monoisotopic_mass": 83204.0 }, "refseq": { "ac": "XP_027269628", "name": "zinc finger protein 11 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269628" }, "gene_names": [ { "name": "LOC100756955", "type": "recommended", "evidence": [ { "id": "A0A8C2MYR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0" } ] }, { "name": "LOC100756955", "type": "synonym", "evidence": [ { "id": "XP_027269628", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269628" } ] } ], "protein_names": [ { "name": "Zinc finger protein 11 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2MYR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 11 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027269628", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269628" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269628", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269628" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100756955", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0", "locus": {} } ], "crossref": [ { "id": "100756955", "url": "https://www.ncbi.nlm.nih.gov/gene/100756955", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756955", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756955", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ENLSDCN", "url": "https://omabrowser.org/oma/group/ENLSDCN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MYR0", "url": "https://www.orthodb.org/?gene=A0A8C2MYR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FVS6", "url": "https://www.orthodb.org/?gene=A0A9J7FVS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390:SF159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390:SF159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404:SF100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404:SF100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269628", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269628", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MYR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MYR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVS6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVS6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNPGTRTPRNGTPRKQFVPESGHDLAVCKPYRVSLLEQRQVPWNVKRQESGTMYPENLCDCNNSVKAFDQHTKLSIRQCVHSEEKPYKQEEHGKAFIDDSASDQHHRVHKGDLPYKCKDCGKAFKYRSVLFQHHIIHTAARPYKCKECGKAFKRSRNLTQHQMTHKRECKYKCKECGKAFTTHSILTQHQIIHTGEKPYKCKECGRSFKYNSTLTQHEVIHTEAKPYTCLECGKAFKRSHTLSQHQIIHKGEKPYKCKECGKAFIKHSSLTQHQVIHTGEKPYRCKECGKAFRYQSTLTRHQILHTGAKPYKCQECGKAFNNSSTLSRHQIIHTGEKPYACQECGRAFYCSSFLIQHMKIHFEEMPYRCKECGKPFRLSSQLIRHQRIHTGEEPYICKECGKTFRYHSNLMRHQILHTGAKPYKCQECGKAFNNSSTLSRHQIIHTGEKSYKCQECGKAFYCSSYLIQHMKIHFEEIPYRCKECGKPFKCSSQLIRHQRIHSGEKPYICKECGKAFNCTSYLTKHQRIHTGEKPYVCKECGKAFNCSSYLSKHQRIHIGDRLYKCKECGKAYYFSSQLNRHQRIHTGEKPYICKECGKAFNCSSYLNKHQRTHIVEKPYVCKECGKAFNCSSYLTKHQRIHTGDRVYKCKECGKAYYFSSQLNRHQRIHTVEKPYRCKECSKAFSTSSSLKRHQETHMLVKPSSVENLAKPQ", "length": 713, "header": "tr|A0A8C2MYR0-1|A0A8C2MYR0_CRIGR Isoform 1 of Zinc finger protein 11 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100756955 PE=3 SV=1 CANONICAL=A0A8C2MYR0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MYR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0/entry#A0A8C2MYR0-1", "sequence": { "sequence": "MRNPGTRTPRNGTPRKQFVPESGHDLAVCKPYRVSLLEQRQVPWNVKRQESGTMYPENLCDCNNSVKAFDQHTKLSIRQCVHSEEKPYKQEEHGKAFIDDSASDQHHRVHKGDLPYKCKDCGKAFKYRSVLFQHHIIHTAARPYKCKECGKAFKRSRNLTQHQMTHKRECKYKCKECGKAFTTHSILTQHQIIHTGEKPYKCKECGRSFKYNSTLTQHEVIHTEAKPYTCLECGKAFKRSHTLSQHQIIHKGEKPYKCKECGKAFIKHSSLTQHQVIHTGEKPYRCKECGKAFRYQSTLTRHQILHTGAKPYKCQECGKAFNNSSTLSRHQIIHTGEKPYACQECGRAFYCSSFLIQHMKIHFEEMPYRCKECGKPFRLSSQLIRHQRIHTGEEPYICKECGKTFRYHSNLMRHQILHTGAKPYKCQECGKAFNNSSTLSRHQIIHTGEKSYKCQECGKAFYCSSYLIQHMKIHFEEIPYRCKECGKPFKCSSQLIRHQRIHSGEKPYICKECGKAFNCTSYLTKHQRIHTGEKPYVCKECGKAFNCSSYLSKHQRIHIGDRLYKCKECGKAYYFSSQLNRHQRIHTGEKPYICKECGKAFNCSSYLNKHQRTHIVEKPYVCKECGKAFNCSSYLTKHQRIHTGDRVYKCKECGKAYYFSSQLNRHQRIHTVEKPYRCKECSKAFSTSSSLKRHQETHMLVKPSSVENLAKPQ", "length": 713, "header": "tr|A0A8C2MYR0-1|A0A8C2MYR0_CRIGR Isoform 1 of Zinc finger protein 11 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100756955 PE=3 SV=1 CANONICAL=A0A8C2MYR0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0/entry#A0A9J7FVS6-1", "sequence": { "sequence": "MYPENLCDCNNSVKAFDQHTKLSIRQCVHSEEKPYKQEEHGKAFIDDSASDQHHRVHKGDLPYKCKDCGKAFKYRSVLFQHHIIHTAARPYKCKECGKAFKRSRNLTQHQMTHKRECKYKCKECGKAFTTHSILTQHQIIHTGEKPYKCKECGRSFKYNSTLTQHEVIHTEAKPYTCLECGKAFKRSHTLSQHQIIHKGEKPYKCKECGKAFIKHSSLTQHQVIHTGEKPYRCKECGKAFRYQSTLTRHQILHTGAKPYKCQECGKAFNNSSTLSRHQIIHTGEKPYACQECGRAFYCSSFLIQHMKIHFEEMPYRCKECGKPFRLSSQLIRHQRIHTGEEPYICKECGKTFRYHSNLMRHQILHTGAKPYKCQECGKAFNNSSTLSRHQIIHTGEKSYKCQECGKAFYCSSYLIQHMKIHFEEIPYRCKECGKPFKCSSQLIRHQRIHSGEKPYICKECGKAFNCTSYLTKHQRIHTGEKPYVCKECGKAFNCSSYLSKHQRIHIGDRLYKCKECGKAYYFSSQLNRHQRIHTGEKPYICKECGKAFNCSSYLNKHQRTHIVEKPYVCKECGKAFNCSSYLTKHQRIHTGDRVYKCKECGKAYYFSSQLNRHQRIHTVEKPYRCKECSKAFSTSSSLKRHQETHMLVKPSSVENLAKPQ", "length": 660, "header": "tr|A0A9J7FVS6-1|A0A8C2MYR0_CRIGR Computationally mapped isoform of Zinc finger protein 11 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100756955 PE=3 SV=1 CANONICAL=A0A8C2MYR0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVS6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVS6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVS6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVS6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756955", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756955", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LLR8-1", "protein_name": "Zinc finger protein 11", "gene_name": "Zfp11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLFCSSWKYIPETLSGTVQGPVTFSFSTSNYPVDVLTHVCIATHCLRSRETFPLLRSQKLGSSYTAPLMKEGIFMSLSAPHPTLPPALAPPPCPDSVTETLRTCVVSVSMWLKPSHAFYILASWCFLYRSPSDAERIFLDAGREPHLSELLSFKDVSVDFSPEEWECLDPARWNLYRNVMLENYRNLVSLGLAVCKPSLVTLLEQIQEPWDVKGQESGTMYPENLSDCNNSAKDFDQHAKLTIHQCAHRKETSDKQEDGDESASDQHLRVRTGDMVYKCKDCGKAFKYRSVLYQHHISHTAARPYKCKECGKAFKRSRNLAQHQVTHKREKPHKCEECGRAFTTLSVLTQHRVTHTGEKPYQCKECGRAFKYNSTLTQHEVIHTEAKPYRCQECGKAFKRSHTLSQHQVTHKGEKPHKCEECGKAFSKHSSLTQHQVIHTGEKPYQCRECGKAFKYQSTLTRHQIVHTGTKPYKCPECGKAFNNSSTLSRHQIIHTGEKPYKCQECGRAFYCSSFLIQHMKIHFEEMPYRCKECGKPFRLSSQLIRHQRIHTGEEPYICKECGKTFKYQSNLTRHQILHTGAKPYKCPECGKAFNNSSTLSRHQIIHTGEKPYKCQECGRAFYCSSYLIQHMKIHFEEIPYRCKECGKPFKCSSQLIRHQRIHSGEKPYICKECGKAFNCTSYLTKHQRTHTGEKPYVCQECGKAFNCSSYLSKHQRIHLGDRLYKCKECGKAYYFSSQLNRHQRIHTGEKPYVCQECGKAFNCSSYLQKHQRIHIVEKPYVCKECGKAFNCSSYLTKHQRVHTGDRSYKCRECGKAYYFSSQLTRHQRTHTREKPYRCKECGKAFITSSSLKRHQETHTLLKPSHV", "length": 867 }, "evidence": [ { "id": "A0A8C2MYR0", "url": "https://omabrowser.org/oma/group/A0A8C2MYR0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10751-1", "protein_name": "Zinc finger protein 11", "gene_name": "Zfp11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPENLSDCNNSVKDFDQHPELTIRQCVHREKPYKQEECDDSACDQHLRVHKGGMPYECKDCGKAFKYRSVLYQHRIIHTAARPYKCKECGKAFKRSRNLAQHQVTHKREKPHKCEECGRAFSALSVLTQHRITHTGEKPFKCKECGRAFKYNSTLTQHEVIHTEAKPYRCQECGKAFKRSHTLSQHQVIHKGEKPHKCDECGRAFSKHSSLTQHQVIHTGEKPYQCRECGKAFRYQSTLTRHHIVHTGAKPYKCPECDKAFNNSSTLSRHQIIHTGEKPYKCQECGRAFYCSSFLIQHMKIHFEEMPYRCRECGKPFRLSSQLIRHQRIHTGEEPYICRECGKTFKYQSNLTRHQILHTGAKPYKCPECGKAFNNSSTLTRHQIIHTGEKPYKCQECSKAFYCSSYLIQHMKIHFEEIPYRCKECGKPFKCSSQLIRHQRIHSGEKPYICKECGKAFNCTSYLTKHQRIHTGEKPYVCQECGKAFNCSSYLSKHQRIHIGDRLYKCKECGKAYYFSSQLNRHQRIHTGEKPYVCQECGKAFNCSSYLTKHQRIHIVEKPYVCKECSKAFSCSSYLTKHQRIHAGDRLYKCTECGKAYCFSSQLNRHQRIHTRERPYRCKECGKAFITSSCLKRHQETHTLQTPNSV", "length": 647 }, "evidence": [ { "id": "A0A8C2MYR0", "url": "https://omabrowser.org/oma/group/A0A8C2MYR0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 546, "end_pos": 548, "annotation": "n_glycosylation_sequon" }, { "start_pos": 602, "end_pos": 604, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MYR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYR0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 116, "end_pos": 143, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 158, "end_pos": 160 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 322, "end_pos": 324 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 434, "end_pos": 436 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 518, "end_pos": 520 }, { "start_pos": 546, "end_pos": 548 }, { "start_pos": 602, "end_pos": 604 }, { "start_pos": 630, "end_pos": 632 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"A0A8C2MYT3_CRIGR", "mass": { "chemical_mass": 53741.0, "monoisotopic_mass": 53741.0 }, "refseq": { "ac": "XP_027250450", "name": "transmembrane protein 161A isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250450" }, "gene_names": [ { "name": "Tmem161a", "type": "recommended", "evidence": [ { "id": "A0A8C2MYT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYT3" } ] }, { "name": "Tmem161a", "type": "synonym", "evidence": [ { "id": "XP_027250450", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250450" } ] } ], "protein_names": [ { "name": "Transmembrane protein 161A", "type": "recommended", "evidence": [ { "id": "A0A8C2MYT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYT3/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 161A isoform X5", "type": "synonym", "evidence": [ { "id": "XP_027250450", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250450" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027250450", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250450" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYT3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYT3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem161a", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYT3", "locus": {} } ], "crossref": [ { "id": "100764636", "url": "https://www.ncbi.nlm.nih.gov/gene/100764636", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764636", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764636", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MYT3", "url": "https://www.orthodb.org/?gene=A0A8C2MYT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13624", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13624", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13624:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13624:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10268", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10268", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027250450", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250450", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MYT3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MYT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F4R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4R8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F4R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4R8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC05", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC05-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVLGVQLVVTLFTATVMHRLAPHCSFARWLLCNGSLFRYVHPSEEELRVLAGKPRPRGRKERWANGLHDEKPLSVPRDAPFQLATCPLTAVDALVLRFFLEYQWFVDFAVYSVGVYLFTEAYYLVLGPVQEANISVFWCLLTLAFSLKVFLMVTRLYFSAKEGGERSVCLTFAFLVLLLAMLVQVVREETLELGLEPGLASVIQNLEPVLKKQGWDWALPVIKLAIRLGLVMLGSLLGAFLIFPGLRLAQTHQDALTLNADRPLLQLLLYTSFLSPLCTLWLWTKPVARDLLYQAPMKNMTSSLPSEGAFDSLRLWVLVVLCLLRLAVTRPHLQAYLCLAKARVEQLRKEAGRIEAREIQQRVVRVYCYVTVVSLQYLTPLILTLHCTLLLKTLGGYSWTLGPAQTPLDPPQSSDTLISVDPAEDEAQQTAAQVAGVLGGLLTPLFLRGVLAYLIWWTAACQLLSSLFGLYFHQHLAAS", "length": 480, "header": "tr|A0A8C2MYT3-1|A0A8C2MYT3_CRIGR Isoform 1 of Transmembrane protein 161A OS=Cricetulus griseus OX=10029 GN=Tmem161a PE=3 SV=1 CANONICAL=A0A8C2MYT3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MYT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYT3/entry#A0A8C2MYT3-1", "sequence": { "sequence": "MAVLGVQLVVTLFTATVMHRLAPHCSFARWLLCNGSLFRYVHPSEEELRVLAGKPRPRGRKERWANGLHDEKPLSVPRDAPFQLATCPLTAVDALVLRFFLEYQWFVDFAVYSVGVYLFTEAYYLVLGPVQEANISVFWCLLTLAFSLKVFLMVTRLYFSAKEGGERSVCLTFAFLVLLLAMLVQVVREETLELGLEPGLASVIQNLEPVLKKQGWDWALPVIKLAIRLGLVMLGSLLGAFLIFPGLRLAQTHQDALTLNADRPLLQLLLYTSFLSPLCTLWLWTKPVARDLLYQAPMKNMTSSLPSEGAFDSLRLWVLVVLCLLRLAVTRPHLQAYLCLAKARVEQLRKEAGRIEAREIQQRVVRVYCYVTVVSLQYLTPLILTLHCTLLLKTLGGYSWTLGPAQTPLDPPQSSDTLISVDPAEDEAQQTAAQVAGVLGGLLTPLFLRGVLAYLIWWTAACQLLSSLFGLYFHQHLAAS", "length": 480, "header": "tr|A0A8C2MYT3-1|A0A8C2MYT3_CRIGR Isoform 1 of Transmembrane protein 161A OS=Cricetulus griseus OX=10029 GN=Tmem161a PE=3 SV=1 CANONICAL=A0A8C2MYT3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F4R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYT3/entry#A0A9J7F4R8-1", "sequence": { "sequence": "MAVLGVQLVVTLFTATVMHRLAPHCSFARWLLCNGSLFRYVHPSEEELRVLAGKPRPRGRKERWANGLHDEKPLSVPRDAPFQLATCPLTAVDALGLASVIQNLEPVLKKQGWDWALPVIKLAIRLGLVMLGSLLGAFLIFPGLRLAQTHQDALTLNADRPLLQLLLYTSFLSPLCTLWLWTKPVARDLLYQAPMKNMTSSLPSEGAFDSLRLWVLVVLCLLRLAVTRPHLQAYLCLAKARVEQLRKEAGRIEAREIQQRVVRVYCYVTVVSLQYLTPLILTLHCTLLLKTLGGYSWTLGPAQTPLDPPQSSDTLISVDPAEDEAQQTAAQVAGVLGGLLTPLFLRGVLAYLIWWTAACQLLSSLFGLYFHQHLAAS", "length": 377, "header": "tr|A0A9J7F4R8-1|A0A8C2MYT3_CRIGR Computationally mapped isoform of Transmembrane protein 161A OS=Cricetulus griseus OX=10029 GN=Tmem161a PE=3 SV=1 CANONICAL=A0A8C2MYT3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HC05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYT3/entry#A0A9J7HC05-1", "sequence": { "sequence": "MAVLGVQLVVTLFTATVMHRLAPHCSFARWLLCNGSLFRYVHPSEEELRVLAGKPRPRGRKERWANGLHDEKPLSVPRDAPFQLATCPLTAVDALVLRFFLEYQWFVDFAVYSVGVYLFTEAYYLVLGPVQEANISVFWCLLTLAFSLKVFLMVTRLYFSAKEGGERSVCLTFAFLVLLLAMLVQVVREETLELGLEPGLASVIQNLEPVLKKQGWDWALPVIKLAIRLGLVMLGSLLGAFLIFPGLRLAQTHQDALTLNADRPLLQLLLYTSFLSPLCTLWLWTKPVARDLLYQAPMKNMTSSLPSEGAFDSLRLWVLVVLCLLRLAVTRPHLQAYLCLAKARVEQLRKEAGRIEAREIQQRVVRVYCYVTVVSLQYLTPLILTLHCTLLLKTLGAG", "length": 398, "header": "tr|A0A9J7HC05-1|A0A9J7HC05_CRIGR Computationally mapped isoform of Transmembrane protein 161A OS=Cricetulus griseus OX=10029 GN=Tmem161a PE=3 SV=1 CANONICAL=A0A8C2MYT3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F4R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4R8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F4R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4R8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764636", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764636", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYT3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYT3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage", "id": "GO:1902230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902230", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYT3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYT3" } ], "pmid": "" }, { "name": "response to retinoic acid", "id": "GO:0032526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032526", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYT3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYT3" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYT3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYT3" } ], "pmid": "" }, { "name": "positive regulation of DNA repair", "id": "GO:0045739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045739", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYT3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYT3" } ], "pmid": "" }, { "name": "cellular response to UV", "id": "GO:0034644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034644", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYT3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYT3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 34, "end_pos": 36 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MYU6-1", "uniprot_ac": "A0A8C2MYU6", "uniprot_id": "A0A8C2MYU6_CRIGR", "mass": { "chemical_mass": 25204.0, "monoisotopic_mass": 25204.0 }, "refseq": { "ac": "XP_003512321", "name": "peptidyl-prolyl cis-trans isomerase FKBP3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512321" }, "gene_names": [ { "name": "Fkbp3", "type": "recommended", "evidence": [ { "id": "A0A8C2MYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYU6" } ] }, { "name": "Fkbp3", "type": "synonym", "evidence": [ { "id": "XP_003512321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512321" } ] } ], "protein_names": [ { "name": "peptidylprolyl isomerase", "type": "recommended", "evidence": [ { "id": "A0A8C2MYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYU6/entry#names_and_taxonomy" } ] }, { "name": "5.2.1.8", "type": "synonym", "evidence": [ { "id": "A0A8C2MYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYU6/entry#names_and_taxonomy" } ] }, { "name": "peptidyl-prolyl cis-trans isomerase FKBP3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003512321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512321" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 149 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615410.1) and transcript sequence (JI864222.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003512321.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003512321", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512321" } ] }, { "annotation": "FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. 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Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027287083", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287083" } ] }, { "annotation": "Probable Fe(2+)/2-oxoglutarate-dependent dioxygenase involved in oxidative demethylation of nucleic acids. Binds nucleic acids with a preference for ssDNA or ssRNA to other types of DNAs. 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This record is derived from a genomic sequence (NW_003613640.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497081", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497081" } ] }, { "annotation": "Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYY7#function" }, { "database": "UniProtKB", "id": "ARBA00024938", "url": "https://www.uniprot.org/uniprotkb/ARBA00024938#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYY7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem214", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYY7", "locus": {} } ], "crossref": [ { "id": "100761817", "url": "https://www.ncbi.nlm.nih.gov/gene/100761817", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019308", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019308", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761817", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761817", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NGSAGKW", "url": "https://omabrowser.org/oma/group/NGSAGKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MYY7", "url": "https://www.orthodb.org/?gene=A0A8C2MYY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13448", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13448", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13448:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13448:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10151", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10151", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003497081", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497081", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MYY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MYY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYY7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARAAGSGGWEVVKKGRRPGASGGGRGVGGSDRRALGEANGVWKYDLSSPIQTTSTLYERGFEKIMKRQNKEQVPPPVVESKKPGNKKQPKKVTAVTSQNQKQGLFRSLEDALKALDVAALKKELDKSQSVFTGNPSVWLKDLASYLNYKLQTPRIEPTLSQYPHDYPYSLVSQELRGIIQGLLTKAAGSVELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDRPKIVTSNLGKFLELLRSHQSRPAKCLTIMWALGQAGFANLTEGLKVWLGIMLPVLGIKSLSPFAIAYLDRLLLMHPNLTKGFGMIGPKDFFPLLDFAYMPNNSLTPSLQEQLCQLFPRLKVLAFGAKPESTLHTYFPSFLSRATPSCPAEMKRELLGSLTQCLTVDPLSTSVWRQLYPKHLSQSSLLLEHLLKSWERIPKKARKSLQETIQSFKLANQELLKKGSGGNEHVVTCDAACKGLLQQARGPRPPWARLLLLLLVFAVGFLCHDFRSHGSFQASLTGWLLRSSGFLPVGQHLCAKLYSCSIQSYSWLQETLPAYGSHLLAVIQPSLQLAWTHTDATVSFLSAHCASYLAYFGDSLAGFLQRVQLPEALHQLLHSLKDLLLLFYHSVLLPLWHLLLAALARAQEHCHQACRGEVTWDCIKTQFGEAARWTWLCLQDVTVAFLDWALAMISQQ", "length": 686, "header": "tr|A0A8C2MYY7-1|A0A8C2MYY7_CRIGR Isoform 1 of Transmembrane protein 214 OS=Cricetulus griseus OX=10029 GN=Tmem214 PE=3 SV=1 CANONICAL=A0A8C2MYY7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MYY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYY7/entry#A0A8C2MYY7-1", "sequence": { "sequence": "MAARAAGSGGWEVVKKGRRPGASGGGRGVGGSDRRALGEANGVWKYDLSSPIQTTSTLYERGFEKIMKRQNKEQVPPPVVESKKPGNKKQPKKVTAVTSQNQKQGLFRSLEDALKALDVAALKKELDKSQSVFTGNPSVWLKDLASYLNYKLQTPRIEPTLSQYPHDYPYSLVSQELRGIIQGLLTKAAGSVELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDRPKIVTSNLGKFLELLRSHQSRPAKCLTIMWALGQAGFANLTEGLKVWLGIMLPVLGIKSLSPFAIAYLDRLLLMHPNLTKGFGMIGPKDFFPLLDFAYMPNNSLTPSLQEQLCQLFPRLKVLAFGAKPESTLHTYFPSFLSRATPSCPAEMKRELLGSLTQCLTVDPLSTSVWRQLYPKHLSQSSLLLEHLLKSWERIPKKARKSLQETIQSFKLANQELLKKGSGGNEHVVTCDAACKGLLQQARGPRPPWARLLLLLLVFAVGFLCHDFRSHGSFQASLTGWLLRSSGFLPVGQHLCAKLYSCSIQSYSWLQETLPAYGSHLLAVIQPSLQLAWTHTDATVSFLSAHCASYLAYFGDSLAGFLQRVQLPEALHQLLHSLKDLLLLFYHSVLLPLWHLLLAALARAQEHCHQACRGEVTWDCIKTQFGEAARWTWLCLQDVTVAFLDWALAMISQQ", "length": 686, "header": "tr|A0A8C2MYY7-1|A0A8C2MYY7_CRIGR Isoform 1 of Transmembrane protein 214 OS=Cricetulus griseus OX=10029 GN=Tmem214 PE=3 SV=1 CANONICAL=A0A8C2MYY7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYY7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYY7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761817", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761817", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A1L1L2-1", "protein_name": "Transmembrane protein 214", "gene_name": "Tmem214", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAARAAGSGGWEVVKRSRRPGASSGGRGGGGDRRALGEANGVWKYDLSSPIQPTSTLYERGFEKIMKRQNKEQVPPPAAESKKPVNKKQPKKVTAVASQNQKQGPFRSLEDALKALDVAALQKELDKSQSVFTGNPSVWLKDLASYLNYKLQTPRMEPTLSQYPHDYPYSLVSRELRGIIRGLLTKAAGSVELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDKPKIVTSNLDKFLELLRSHQSRPAKCLTIMWALGQAGFTNLTEGLKVWLGIMLPVLGIKSLSPFAIAYLDRLLLMYPNLTKGFGMIGPKDFFPLLDFAYMPNNSLSPSLQEQLCQLFPRLKVLAFGAKPESSLHTYFPSFLSRATPSCPAAMKKELLASLTQCLTVDPLSTSVWRQLYPKHLSQSSLLLEHLLTSWEQIPKKARKCLQETIQSFTLTNQELLKKGSGSNEHVVTCDTACKGLLQQARGPRPPWARLLLLLLVFAVGFLCHDLRSHSSFQASLTGRLLQSSGLLPVAQQVCAKLYSYSLQSYNWLQETLPACGSYLLAVVQPSLQLAWTYIYATFSFLSAYCASYLAFFSDSLAGVLQRVQLPEALHQLFHSLKELLLLFYHSVLLPMWHLLLAALAQVQEHCHEACRGEMTWDCIKTQFSTAAHWTWLCLQDVTVAFLDWALTMISQQ", "length": 685 }, "evidence": [ { "id": "A0A8C2MYY7", "url": "https://omabrowser.org/oma/group/A0A8C2MYY7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A4FV45-1", "protein_name": "Transmembrane protein 214", "gene_name": "TMEM214", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAKTAGGGRWEVVKKGRRPGAGGSGKGGGGDRRALGEANGVWKYDLTPPIQTTSTLYERGFEKIMKRQNKEQVPPPAVEPKKPGNKKQAKKVATLTNQNQKQGRFRSLEEALKALDLADLQKELDKSQSVFSGNPSVWLKDLASYLNYKLQVPPSEPTLSQHPHDYPYSLVSRELRGIIRGLLAKAAGSLELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDKPKIVTTNLGKFLELLRSHQSRPAKCLTIMWALGQAGFTNLTEGLRVWLGIMLPVLGIKSLSPFAIAYLDRLLLMHPNLTKGFGMIGPKDLFPLLDFAYMPNNSLTPSLQEQLCQLYPRLKVLAFGAKPESTLHTYFPSFLSRATPGCPLEMKKELLRSLTECLMVDPLSTSVWRQLYPKHLSQSSLLLEHLLRSWERIPKKTQKSLQETIQSFKLTNQDLLRKGGGSNQDVVTCDSACKSLLQQARGFQLPWTRLLLLVLVFAIGFLCHDFRSHSSFQASLSGQLLQSSGVLPAGQQACTKIYSYSLQGYSWLEKTLPAWGSHLLTVVRPGLQLAWAHTNATVGFLSAHCASHLAWFGDSLANLFQRLQTQLPDTLNQLLRSLRELLLFLYHSILLPTWHMLLEALAQIQEHCHEACRGEVTWDCMKTQLSEAAHWTWLRLQDTTVAFLDWALAMISQQ", "length": 687 }, "evidence": [ { "id": "A0A8C2MYY7", "url": "https://omabrowser.org/oma/group/A0A8C2MYY7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QEL0-1", "protein_name": "Transmembrane protein 214", "gene_name": "tmem214", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASGVGKWEVVKKGKKATSSSKTQDKKSARKALREANTDSNHVMSETIFDGFEKMVKKQNKEQVPPPVETQQKKPNAGKQTKKPPANSSPKPVHYKTLEEAVKALNIAELKQQLEKSQTLFPENPSIWVKDLAGYLNYKLPAPDTDPTLSSYAHDYPYCLAGKELKAIIKNLLGKCSDALPEFFDHCVFTMLREQDRQPSDPLHGYRMCIQALMQDKPKIATLNLSDHLELLRSHQNRPLKCLTIMWALGQAGFYDLSQGIRVWLGIMLPVLGMKALSAYAIAYLERLLTLHANLTKGFGIMGPKEFFPLLDFAYMPKNALSQSLQEQLCRLYPRIKVLAFGAKPESTLHTYFPSFLSRATPNCPGAMKKELLRSLTECLSVDSQSLSVWRQLYTKHLPQSSLLLNHLLKTWKTLPLKLQKSLQDTIQSFRVTNDELQSGAHTQEISDCNSLCQSLQLKMHGQSVPWWRVLLMLLVCVLGFVAHDVRTQGSFSDSRTAVFLEQLGVSGASQQAWSRVSHYSQQSLSWLSENTPYYYSSAVTAVRPLLEYGQEYVKLAVLKIAHMSSELMLWMQENLPLLLHWIHANTPESVFQFLEFLKGLLLFVHEQMILPALHYLNTALQLAWRSLQESCNGEVSLHCLQDHVRSFTNSTWIYLQDATSAIKSRAQELLS", "length": 672 }, "evidence": [ { "id": "A0A8C2MYY7", "url": "https://omabrowser.org/oma/group/A0A8C2MYY7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6NUQ4-1", "protein_name": "Transmembrane protein 214", "gene_name": "TMEM214", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATKTAGVGRWEVVKKGRRPGVGAGAGGRGGGRNRRALGEANGVWKYDLTPAIQTTSTLYERGFENIMKRQNKEQVPPPAVEPKKPGNKKQPKKVATPPNQNQKQGRFRSLEEALKALDVADLQKELDKSQSVFSGNPSIWLKDLASYLNYKLQAPLSEPTLSQHTHDYPYSLVSRELRGIIRGLLAKAAGSLELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDKPKIATANLGKFLELLRSHQSRPAKCLTIMWALGQAGFANLTEGLKVWLGIMLPVLGIKSLSPFAITYLDRLLLMHPNLTKGFGMIGPKDFFPLLDFAYMPNNSLTPSLQEQLCQLYPRLKVLAFGAKPDSTLHTYFPSFLSRATPSCPPEMKKELLSSLTECLTVDPLSASVWRQLYPKHLSQSSLLLEHLLSSWEQIPKKVQKSLQETIQSLKLTNQELLRKGSSNNQDVVTCDMACKGLLQQVQGPRLPWTRLLLLLLVFAVGFLCHDLRSHSSFQASLTGRLLRSSGFLPASQQACAKLYSYSLQGYSWLGETLPLWGSHLLTVVRPSLQLAWAHTNATVSFLSAHCASHLAWFGDSLTSLSQRLQIQLPDSVNQLLRYLRELPLLFHQNVLLPLWHLLLEALAWAQEHCHEACRGEVTWDCMKTQLSEAVHWTWLCLQDITVAFLDWALALISQQ", "length": 689 }, "evidence": [ { "id": "A0A8C2MYY7", "url": "https://omabrowser.org/oma/group/A0A8C2MYY7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BM55-1", "protein_name": "Transmembrane protein 214", "gene_name": "Tmem214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAARSAGSGGWEVVKRGRRPGASSGGRGGGGGSDRRALGEANGVLKYDLSSPIQTTSTLYERGFEKIMKRQNKEQVPPPAAESKKPINKKQPKKVTAVPSQNQKQGPFRRLEDALKALDVAALQKELDKSQSVFTGNPSVWLKDLASYLNYKLQTPRMEPTLSQYPHDYPYSLVSRELRGIIRGLLTKAAGSVELFFDHCLFTMLQELDKTPGESLHGYRICIQAVLQDKPKIVTSNLDKFLELLRSHQSRPAKCLTIMWALGQAGFTNLTEGLKVWLGIMLPVLGIKALSPFAIAYLDRLLLMHPNLTKGFGMIGPKDFFPLLDFAYMPNNSLSPSLQEQLCQLFPRLKVLAFGAKPESSLHTYFPSFLSRATPSCPAAMKKELLASLTQCLTVDPLSTSVWRQLYPKHLSQSSLLLEHLLKSWEHIPKKARKSLQETIQSLKVTNQELLKKGSGGSEHVLTCDTACKGLLQRARGPRPPWARLFLLLLVFAVGFLCHDLRSNSSLQASLTGRLLRSSGLLPVGQQVCARLSSYSLQSYNWLQETLPACGSHLLAVVQPSLQLAWTHIYAIFSFLSAHCASYLACFSDSLAGFFQRVQLPEALQQLFHALKELLLLFCHSVLLPTWHLLLAALAQVQEHCHEACRGDVTWDCIKTQLSRAAQWTWLCLQDVTVAFLDWALTMISQQ", "length": 687 }, "evidence": [ { "id": "A0A8C2MYY7", "url": "https://omabrowser.org/oma/group/A0A8C2MYY7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VKM7-1", "protein_name": "Transmembrane protein 214, isoform E", "gene_name": "Tmem214", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSEQWEVVSKSRKQKNLDKKVSAHNEQKRIAAQLPKLEELLPTQRYRNLFGSSNNNNSKSHSPAKSSSSASSSSKANKSPVKKHTAKNASTQKRTTSAAASKPKTLELALRNITRDDFAAQLEQVKLSCPGSELRWLSHIALYFNEALSYDCDPIFSGRSAQYPSNLASASLKYSIVEFLGSVGEQNLEYFFYSLLDSMSTDLNNNQTVAGYKLILQLIGQNWPNICSRNLAKTALLRNSYQNRSNICLSILWAIGQGGYQSLNEGVRVWQNLMLPNLELKQYTKFVVEYMERALSAAAVRKTADPLQINQQEFFATYNALNAPYNHLPKEWQQSLKRSARLLLQHYINSPVRHANIFLTLFREISAGSKQTNEIEGCISCLLSSGRDDCLRVWRMNYKKQQLPSLLLLKAINDNWTTSTHELATSTVYHSFLQDVANLNEELQGSKRNEGHLDDLKEVLLSVQEKSSAQQKKNKQKAAAEKKKCGCCKWTLGSIFIIALIAGALYYDTEVNGKGVFEKSATGKVLKNAGVLPHVQKSWYTVMGAGARGYKWAEVNVPPYAEPVIKTTCDLWKLARNAACNAYQNGKGYFGAKWPVVAKFIDQYVPNSSGKIEAFAAGVSDLAASSYEKAAALIKEKVLVGRLSPENINQALNQTRNAALEYYNQFHKKVDAYAKLK", "length": 677 }, "evidence": [ { "id": "A0A8C2MYY7", "url": "https://omabrowser.org/oma/group/A0A8C2MYY7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYY7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYY7" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYY7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 268, "end_pos": 270 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 330, "end_pos": 332 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MZ37-1", "uniprot_ac": "A0A8C2MZ37", "uniprot_id": "A0A8C2MZ37_CRIGR", "mass": { "chemical_mass": 56155.0, "monoisotopic_mass": 56155.0 }, "refseq": { "ac": "XP_027248287", "name": "BPI fold-containing family C protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248287" }, "gene_names": [ { "name": "Bpifc", "type": "recommended", "evidence": [ { "id": "A0A8C2MZ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ37" } ] }, { "name": "Bpifc", "type": "synonym", "evidence": [ { "id": "XP_027248287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248287" } ] } ], "protein_names": [ { "name": "Bactericidal permeability-increasing protein", "type": "recommended", "evidence": [ { "id": "A0A8C2MZ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ37/entry#names_and_taxonomy" } ] }, { "name": "BPI fold-containing family C protein", "type": "synonym", "evidence": [ { "id": "XP_027248287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248287" } ] }, { "name": "BPI", "type": "synonym", "evidence": [ { "id": "A0A8C2MZ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ37/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027248287", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248287" } ] }, { "annotation": "The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZ37", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ37#function" }, { "database": "UniProtKB", "id": "RU369039", "url": "https://www.uniprot.org/uniprotkb/RU369039#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZ37", "url": 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Classification" ] }, { "id": "IPR030675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752136", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752136", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TEPPMIN", "url": "https://omabrowser.org/oma/group/TEPPMIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MZ37", "url": "https://www.orthodb.org/?gene=A0A8C2MZ37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10504", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10504", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10504:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10504:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01273", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01273", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02886", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02886", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027248287", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248287", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZ37", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZ37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTKQVPVLWACFLLWNLYISSSQAVYPGIKARITQRALDYGVQVGMKMMEEMAKEIAIPDLKGSESLEFLKIDYVKYNFSNIKINAFSLPNSSLAFVPGVGIRALSNHGTANISANWEVRAPLFQDSGAADLFLSGIYFTGIIVLTRDNLGHPAVELQDCRAQVSHARVSFSGGLSVLYNSFAEPMEKPILRNLNEMLCPIVINEVDALNVNISALEVLTKIDNYTVLDCSLMSPPEVTENHLDLNLKGAFYPLESLVDPPFLPAPFELPRNKDSMLCIGVSEYFFKSASFAHYVSGALGVMLSTKEISNYFNQNTQGIGSVLSKIAEIYVLSQPFMLQIMATGPPVINLHPNNFSLEFPAAVIMLTELQNSTIEPIVSMDFIASTSVGLAILGQKLICSLSLNRFRLSLPQNSHRDAKVVRFENILSSILHFGVLPLANTKLQQGFPLPNPYNISFVNSDIEVLEGFLLISTDLAHETSSRQQPNLHSWGGLNLVNRPWREQPTH", "length": 507, "header": "tr|A0A8C2MZ37-1|A0A8C2MZ37_CRIGR Isoform 1 of Bactericidal permeability-increasing protein OS=Cricetulus griseus OX=10029 GN=Bpifc PE=3 SV=1 CANONICAL=A0A8C2MZ37-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZ37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ37/entry#A0A8C2MZ37-1", "sequence": { "sequence": "MRTKQVPVLWACFLLWNLYISSSQAVYPGIKARITQRALDYGVQVGMKMMEEMAKEIAIPDLKGSESLEFLKIDYVKYNFSNIKINAFSLPNSSLAFVPGVGIRALSNHGTANISANWEVRAPLFQDSGAADLFLSGIYFTGIIVLTRDNLGHPAVELQDCRAQVSHARVSFSGGLSVLYNSFAEPMEKPILRNLNEMLCPIVINEVDALNVNISALEVLTKIDNYTVLDCSLMSPPEVTENHLDLNLKGAFYPLESLVDPPFLPAPFELPRNKDSMLCIGVSEYFFKSASFAHYVSGALGVMLSTKEISNYFNQNTQGIGSVLSKIAEIYVLSQPFMLQIMATGPPVINLHPNNFSLEFPAAVIMLTELQNSTIEPIVSMDFIASTSVGLAILGQKLICSLSLNRFRLSLPQNSHRDAKVVRFENILSSILHFGVLPLANTKLQQGFPLPNPYNISFVNSDIEVLEGFLLISTDLAHETSSRQQPNLHSWGGLNLVNRPWREQPTH", "length": 507, "header": "tr|A0A8C2MZ37-1|A0A8C2MZ37_CRIGR Isoform 1 of Bactericidal permeability-increasing protein OS=Cricetulus griseus OX=10029 GN=Bpifc PE=3 SV=1 CANONICAL=A0A8C2MZ37-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZ37", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ37" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZ37", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ37" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752136", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752136", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8NFQ6-1", "protein_name": "BPI fold-containing family C protein", "gene_name": "BPIFC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCTKTIPVLWGCFLLWNLYVSSSQTIYPGIKARITQRALDYGVQAGMKMIEQMLKEKKLPDLSGSESLEFLKVDYVNYNFSNIKISAFSFPNTSLAFVPGVGIKALTNHGTANISTDWGFESPLFQDTGGADLFLSGVYFTGIIILTRNDFGHPTLKLQDCYAQLSHAHVSFSGELSVLYNSFAEPMEKPILKNLNEMLCPIIASEVKALNANLSTLEVLTKIDNYTLLDYSLISSPEITENYLDLNLKGVFYPLENLTDPPFSPVPFVLPERSNSMLYIGIAEYFFKSASFAHFTAGVFNVTLSTEEISNHFVQNSQGLGNVLSRIAEIYILSQPFMVRIMATEPPIINLQPGNFTLDIPASIMMLTQPKNSTVETIVSMDFVASTSVGLVILGQRLVCSLSLNRFRLALPESNRSNIEVLRFENILSSILHFGVLPLANAKLQQGFPLSNPHKFLFVNSDIEVLEGFLLISTDLKYETSSKQQPSFHVWEGLNLISRQWRGKSAP", "length": 507 }, "evidence": [ { "id": "A0A8C2MZ37", "url": "https://omabrowser.org/oma/group/A0A8C2MZ37/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VYC2-1", "protein_name": "Putative BPI/LBP family protein At3g20270", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A8C2N1C7" } ] }, { "name": "Ptbp3", "type": "synonym", "evidence": [ { "id": "XP_007644195", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644195" } ] } ], "protein_names": [ { "name": "Polypyrimidine tract-binding protein 3", "type": "recommended", "evidence": [ { "id": "A0A8C2N1C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7/entry#names_and_taxonomy" } ] }, { "name": "Regulator of differentiation 1", "type": "synonym", "evidence": [ { "id": "A0A8C2N1C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7/entry#names_and_taxonomy" } ] }, { "name": "polypyrimidine tract-binding protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007644195", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644195" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 183 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614157.1) and transcript sequence (IACG01034749.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007644195.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007644195", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644195" } ] }, { "annotation": "RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes Fas exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U).", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FF75", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF75#function" }, { "database": "UniProtKB", "id": "ARBA00059066", "url": "https://www.uniprot.org/uniprotkb/ARBA00059066#function" }, { "database": "UniProtKB", "id": "A0A9J7FJW1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJW1#function" }, { "database": "UniProtKB", "id": "A0A8C2N1C7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N1C7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ptbp3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7", "locus": {} } ], "crossref": [ { "id": "cd12779", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12779", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12784", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12784", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771699", "url": "https://www.ncbi.nlm.nih.gov/gene/100771699", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771699", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771699", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N1C7", "url": "https://www.orthodb.org/?gene=A0A8C2N1C7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007644195", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644195", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZ48", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZ48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N1C7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N1C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FF75", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FF75-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FJW1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FJW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GPL5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GPL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GS29", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GS29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GS29-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GS29-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGVVTDLIAVGLKRGSDELLSPGVINGPSTMNNSTPSGVYANGNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGAPSNEGAVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPLNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTLTSSAVTGRMAIPGASGIPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI", "length": 554, "header": "tr|A0A8C2N1C7-1|A0A8C2N1C7_CRIGR Isoform 1 of Polypyrimidine tract-binding protein 3 OS=Cricetulus griseus OX=10029 GN=Ptbp3 PE=4 SV=1 CANONICAL=A0A8C2N1C7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZ48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7/entry#A0A8C2MZ48-1", "sequence": { "sequence": "MAFLEMASEEAAVTMVNYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGAPSNEGAVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPLNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTLTSSAVTGRMAIPGASGIPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI", "length": 457, "header": "tr|A0A8C2MZ48-1|A0A8C2N1C7_CRIGR Computationally mapped isoform of Polypyrimidine tract-binding protein 3 OS=Cricetulus griseus OX=10029 GN=Ptbp3 PE=4 SV=1 CANONICAL=A0A8C2N1C7-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N1C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7/entry#A0A8C2N1C7-1", "sequence": { "sequence": "MDGVVTDLIAVGLKRGSDELLSPGVINGPSTMNNSTPSGVYANGNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGAPSNEGAVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPLNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTLTSSAVTGRMAIPGASGIPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI", "length": 554, "header": "tr|A0A8C2N1C7-1|A0A8C2N1C7_CRIGR Isoform 1 of Polypyrimidine tract-binding protein 3 OS=Cricetulus griseus OX=10029 GN=Ptbp3 PE=4 SV=1 CANONICAL=A0A8C2N1C7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FF75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7/entry#A0A9J7FF75-1", "sequence": { "sequence": "MDGVVTDLIAVGLKRGSDELLSPGVINGPSTMNNSTPSANGNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGAPSNEGAVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPLNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTLTSSAVTGRMAIPGASGIPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI", "length": 551, "header": "tr|A0A9J7FF75-1|A0A8C2N1C7_CRIGR Computationally mapped isoform of Polypyrimidine tract-binding protein 3 OS=Cricetulus griseus OX=10029 GN=Ptbp3 PE=4 SV=1 CANONICAL=A0A8C2N1C7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FJW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7/entry#A0A9J7FJW1-1", "sequence": { "sequence": "MNNSTPSANGNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGAPSNEGAVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPLNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTLTSSAVTGRMAIPGASGIPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI", "length": 520, "header": "tr|A0A9J7FJW1-1|A0A8C2N1C7_CRIGR Computationally mapped isoform of Polypyrimidine tract-binding protein 3 OS=Cricetulus griseus OX=10029 GN=Ptbp3 PE=4 SV=1 CANONICAL=A0A8C2N1C7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GPL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7/entry#A0A9J7GPL5-1", "sequence": { "sequence": "MLKGKSQAFLEMASEEAAVTMVNYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGAPSNEGAVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPLNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTLTSSAVTGRMAIPGASGIPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI", "length": 463, "header": "tr|A0A9J7GPL5-1|A0A9J7GPL5_CRIGR Computationally mapped isoform of Polypyrimidine tract-binding protein 3 isoform X6 OS=Cricetulus griseus OX=10029 GN=Ptbp3 PE=4 SV=1 CANONICAL=A0A8C2N1C7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GS29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7/entry#A0A9J7GS29-1", "sequence": { "sequence": "MASEEAAVTMVNYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGAPSNEGAVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPLNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTLTSSAVTGRMAIPGASGIPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI", "length": 452, "header": "tr|A0A9J7GS29-1|A0A9J7GS29_CRIGR Computationally mapped isoform of Polypyrimidine tract-binding protein 3 isoform X8 OS=Cricetulus griseus OX=10029 GN=Ptbp3 PE=4 SV=1 CANONICAL=A0A8C2N1C7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FF75", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF75" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FF75", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF75" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771699", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771699", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N1C7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N1C7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N1C7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7" } ], "pmid": "" }, { "name": "erythrocyte maturation", "id": "GO:0043249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043249", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N1C7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N1C7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1C7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027249015", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249015" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZ64", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ64" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Scamp3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ64", "locus": {} } ], "crossref": [ { "id": "100756052", "url": "https://www.ncbi.nlm.nih.gov/gene/100756052", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756052", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756052", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MZ64", "url": "https://www.orthodb.org/?gene=A0A8C2MZ64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10687", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10687", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10687:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10687:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027249015", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249015", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZ64", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZ64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JBB2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JBB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBB2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQSRDGGNPFPDSDELDNPFQDPAVIQHRPSQQYATLDVYNPFENREPPPAYEPPAPAPAPAPLPPPAAPSVQSSRKLSPTEPKNYGSYSTQASAVAATAELLRKQEELNRKAEELDRRERELQHVALGGTHTRQNNWPPLPSFCPVQPCFFQDISMEIPQEFQKTVSTMYYLWMCSTLALLLNFLACLAKFCVETSSGSGFGLSMLWLLLFTPCSFVCWYRPMYKAFRSDSSFNFFVFFFIFFVQDVFFVLQAIGIPGWGFSGWVSAIVTVSTNTAVAVLMLLVALLFTGVAVLGIVMLKRIHSLYRRTGASFQKAQQEFAAGVFSNPAVRTAAANAAAGAAENAFRVP", "length": 351, "header": "tr|A0A8C2MZ64-1|A0A8C2MZ64_CRIGR Isoform 1 of Secretory carrier-associated membrane protein OS=Cricetulus griseus OX=10029 GN=Scamp3 PE=3 SV=1 CANONICAL=A0A8C2MZ64-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZ64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ64/entry#A0A8C2MZ64-1", "sequence": { "sequence": "MAQSRDGGNPFPDSDELDNPFQDPAVIQHRPSQQYATLDVYNPFENREPPPAYEPPAPAPAPAPLPPPAAPSVQSSRKLSPTEPKNYGSYSTQASAVAATAELLRKQEELNRKAEELDRRERELQHVALGGTHTRQNNWPPLPSFCPVQPCFFQDISMEIPQEFQKTVSTMYYLWMCSTLALLLNFLACLAKFCVETSSGSGFGLSMLWLLLFTPCSFVCWYRPMYKAFRSDSSFNFFVFFFIFFVQDVFFVLQAIGIPGWGFSGWVSAIVTVSTNTAVAVLMLLVALLFTGVAVLGIVMLKRIHSLYRRTGASFQKAQQEFAAGVFSNPAVRTAAANAAAGAAENAFRVP", "length": 351, "header": "tr|A0A8C2MZ64-1|A0A8C2MZ64_CRIGR Isoform 1 of Secretory carrier-associated membrane protein OS=Cricetulus griseus OX=10029 GN=Scamp3 PE=3 SV=1 CANONICAL=A0A8C2MZ64-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JBB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ64/entry#A0A9J7JBB2-1", "sequence": { "sequence": "MAQSRDGGNPFPDSDELDNPFQDPAVIQHRPSQQYATLDVYNPFENREPPPAYEPPAPAPAPAPLPPPAAPSVQSSRKLSPTEPKNYGSYSTQASAVAATAELLRKQEELNRKAEELDRRERELQHVALGGTHTRQNNWPPLPSFCPVQPCFFQDISMEIPQEFQKTVSTMYYLWMCSTLALLLNFLACLAKFCVETSSGSGFGLSMLWLLLFTPCSFVCWYRPMYKAFRSDSSFNFFVFFFIFFVQDVFFVLQAIGIPGWGFRSTPCTAEQVPAFRKPSKNLLPESSPTQQFELLPPMQPQGLLKMPSGSHNPHWDVLTLPPVGTKIVPIPEVSGIQGDITTY", "length": 344, "header": "tr|A0A9J7JBB2-1|A0A9J7JBB2_CRIGR Computationally mapped isoform of Secretory carrier-associated membrane protein OS=Cricetulus griseus OX=10029 GN=Scamp3 PE=3 SV=1 CANONICAL=A0A8C2MZ64-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZ64", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ64" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZ64", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ64" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756052", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756052", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZ64", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ64" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZ64", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ64" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZ64", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ64" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZ64", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MZC6-1", "uniprot_ac": "A0A8C2MZC6", "uniprot_id": "A0A8C2MZC6_CRIGR", "mass": { "chemical_mass": 57762.0, "monoisotopic_mass": 57762.0 }, "refseq": { "ac": "XP_003504274", "name": "ETS translocation variant 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504274" }, "gene_names": [ { "name": "Etv5", "type": "recommended", "evidence": [ { "id": "A0A8C2MZC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZC6" } ] }, { "name": "Etv5", "type": "synonym", "evidence": [ { "id": "XP_003504274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504274" } ] } ], "protein_names": [ { "name": "ETS translocation variant 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003504274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504274" }, { "id": "A0A8C2MZC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZC6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 131 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614046.1) and transcript sequence (IACG01088581.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003504274.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504274" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZC6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZC6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Etv5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZC6", "locus": {} } ], "crossref": [ { "id": "100756646", "url": "https://www.ncbi.nlm.nih.gov/gene/100756646", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006715", "url": 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}, { "id": "PTHR11849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849:SF160", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849:SF160", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504274", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZC6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZC6-1", "url": 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translocation variant 5 isoform X1 OS=Cricetulus griseus OX=10029 GN=Etv5 PE=3 SV=1 CANONICAL=A0A8C2MZC6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZC6/entry#A0A8C2MZC6-1", "sequence": { "sequence": "MDGFCDQQVPFMVPGKSRSEECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLAEAQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSSCSHEQALGANYGEKCLYNYCAYDRKPPSGFKPLTPPTTPLSPTHQNPLFPPPQATLPTSALAPGAGPVQGVGPAPTPHSLPEPGSQQQTFAVPRPPHQPLQMPKMMPESQYPSEQRFQRQLSEPCHPFPPQSGVPGDNRPSYHRQMSEPIVPAAPPPLQGFKQEYHDPLYEHGVPGMPGPPAHGFQSPMGIKQEPRDYCADSEVPNCQSSYMRGGYFSSNHEGFTYEKDPRLYFDDTCVVPERLEGKVKQEPTLYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESECPLNEEDTLPLTHFEDNPAYLLDMDRCSSLPYAEGFAY", "length": 510, "header": "tr|A0A8C2MZC6-1|A0A8C2MZC6_CRIGR Isoform 1 of ETS translocation variant 5 isoform X1 OS=Cricetulus griseus OX=10029 GN=Etv5 PE=3 SV=1 CANONICAL=A0A8C2MZC6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FU43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZC6/entry#A0A9J7FU43-1", "sequence": { "sequence": "MRGGYFSSNHEGFTYEKDPRLYFDDTCVVPERLEGKVKQEPTLYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESECPLNEEDTLPLTHFEDNPAYLLDMDRCSSLPYAEGFAY", "length": 198, "header": "tr|A0A9J7FU43-1|A0A8C2MZC6_CRIGR Computationally mapped isoform of ETS translocation variant 5 isoform X1 OS=Cricetulus griseus OX=10029 GN=Etv5 PE=3 SV=1 CANONICAL=A0A8C2MZC6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 177, "start_aa": "Thr", "end_pos": 177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr177", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU43" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU43" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756646", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756646", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B0S6S7-1", "protein_name": "ETS translocation variant 5a isoform X1", "gene_name": "etv5a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDGFYDQQVPFMVPPNQKSLQVEEPYNRPVNDRKRKLVETELAQDTEELFQDLSQLQEIWIAEAQVPDDEQFVPDFQSESLMFHGPPLAKIKRELSPSKELSPCSQDRSPMPYGEKCLYSYSAYERKPSTGFKPLTPPSTPVSPCVPSNALATRPLHEQTPPPVSNTALGQRLLHGQPTMTKSTPNQTCVPHHSQSPPFVVPCPPLNRETHFSNEPRFQRQLSEPCLPFPPSDAQGRPSFMPQVACTSPRDGRPPYHRQMSEPLVPVPPQGFKQELLDPRYVEQGVPNMGPSQAAFHPMAIKQEPRDFCFDSEVPKCQSSFGRAASFYQNHENFSFDREQQLYFDDTCVVPERLEGKVKQEPSVYREGPPYQRRGSLQLWQFLVTLLDDPSNGHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVKVAGERYVYKFVCDPEALFSMAFPDNQRPNLKADPDGLPTVDDDTLPLAHYDDGSSYLVDGGEQCVSGMPFPDGYVY", "length": 524 }, "evidence": [ { "id": "A0A8C2MZC6", "url": "https://omabrowser.org/oma/group/A0A8C2MZC6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4AC56-1", "protein_name": "ETS variant transcription factor 5", "gene_name": "Etv5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGFCDQQVPFMVPGKSRSEDCRGRPVIDRKRKFVDTDLAHDSEELFQDLSQLQEAWLAEAQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSSCSHEQALGAKYGEKCLYNYCAYDRKPPSGFKPLTPPATPLSPTHQNSLFPPPQATLPTSALAPGAGPVQGVGPAPTPHSLPEPGSQQQTFAVPRPPHQPLQMPKMMPESQYPSEQRFQRQLSEPCRPFPPQSGVPGDTRPSYQRQMSEPVVPAAPPPLQGFKQEYHDPLYEHGVPGMPGPPAHGFQSPMGIKQEPRDYCADSEVPNCQSPYMRGRYFSSNHEGFTYEKDPRLYFDDTCVVPERLEGKVKQEPTMYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESDCPLNEEDTLPLTHFEDSPAYLLDMDRCSGLPYAEGFAY", "length": 510 }, "evidence": [ { "id": "A0A8C2MZC6", "url": "https://omabrowser.org/oma/group/A0A8C2MZC6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P41161-1", "protein_name": "ETS translocation variant 5", "gene_name": "ETV5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGFYDQQVPFMVPGKSRSEECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLAEAQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSSCSHEQALGANYGEKCLYNYCAYDRKPPSGFKPLTPPTTPLSPTHQNPLFPPPQATLPTSGHAPAAGPVQGVGPAPAPHSLPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPGVPGDNRPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGMPGPPAHGFQSPMGIKQEPRDYCVDSEVPNCQSSYMRGGYFSSSHEGFSYEKDPRLYFDDTCVVPERLEGKVKQEPTMYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESECHLSEEDTLPLTHFEDSPAYLLDMDRCSSLPYAEGFAY", "length": 510 }, "evidence": [ { "id": "A0A8C2MZC6", "url": "https://omabrowser.org/oma/group/A0A8C2MZC6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CXC9-1", "protein_name": "ETS translocation variant 5", "gene_name": "Etv5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGFCDQQVPFMVPGKSRSEDCRGRPLIDRKRKFVDTDLAHDSEELFQDLSQLQEAWLAEAQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSSCSHEQALGAKYGEKCLYNYCAYDRKPPSGFKPLTPPATPLSPTHQNSLFPPPQATLPTSGLTPGAGPVQGVGPAPTPHSLPEPGSQQQTFAVPRPPHQPLQMPKMMPESQYPSEQRFQRQLSEPSHPFPPQSGVPGDSRPSYHRQMSEPIVPAAPPPLQGFKQEYHDPLYEHGVPGMPGPPAHGFQSPMGIKQEPRDYCADSEVPNCQSSYMRGGYFSSSHEGFPYEKDPRLYFDDTCVVPERLEGKVKQEPTMYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESECPLNEEDTLPLTHFEDNPAYLLDMDRCSSLPYTEGFAY", "length": 510 }, "evidence": [ { "id": "A0A8C2MZC6", "url": "https://omabrowser.org/oma/group/A0A8C2MZC6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZC6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZC6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZC6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZC6" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZC6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZC6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZC6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZC6" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZC6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MZC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZC6" }, { "id": "PS50061", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ETS", "eco_id": "ECO_0000259", "start_pos": 368, "end_pos": 448, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 177 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MZE7-1", "uniprot_ac": "A0A8C2MZE7", "uniprot_id": "A0A8C2MZE7_CRIGR", "mass": { "chemical_mass": 32485.0, "monoisotopic_mass": 32485.0 }, "refseq": { "ac": "XP_027256573", "name": "CXXC-type zinc finger protein 5 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256573" }, "gene_names": [ { "name": "Cxxc5", "type": "recommended", "evidence": [ { "id": "A0A8C2MZE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZE7" } ] }, { "name": "Cxxc5", "type": "synonym", "evidence": [ { "id": "XP_027256573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256573" } ] } ], "protein_names": [ { "name": "CXXC-type zinc finger protein 5", "type": "recommended", "evidence": [ { "id": "A0A8C2MZE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZE7/entry#names_and_taxonomy" } ] }, { "name": "CXXC-type zinc finger protein 5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027256573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256573" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027256573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256573" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZE7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cxxc5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZE7", "locus": {} } ], "crossref": [ { "id": "100758671", "url": "https://www.ncbi.nlm.nih.gov/gene/100758671", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758671", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758671", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MZE7", "url": "https://www.orthodb.org/?gene=A0A8C2MZE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13419", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13419:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13419:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027256573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256573", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSLGGGSQDAGGSSSSTNSSSGSGPKAGGTDKSTTVAAATPASVADDAPPPERRNKSGIISEPLNKSLRRSRPLSHYSSFGSSGGSGSLIGGEPADKAAAAAASLLANGHDLAAAMAVDKSNPTSKHKSGAVASLLSKAERATELAAEGQLTLQQFAQSTEMLKRVVQEHLPLMSEAGAGLPDMEAVASAEALNGQSDFPYLGAFPINPGLFIMTPAGVFLAESALHMAGLAEYPMQGELASAISSGKKKRKRCGMCAPCRRRINCEQCSSCRNRKTGHQICKFRKCEELKKKPSAALEKVMLPTGAAFRWFQ", "length": 314, "header": "tr|A0A8C2MZE7-1|A0A8C2MZE7_CRIGR Isoform 1 of CXXC-type zinc finger protein 5 OS=Cricetulus griseus OX=10029 GN=Cxxc5 PE=4 SV=1 CANONICAL=A0A8C2MZE7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZE7/entry#A0A8C2MZE7-1", "sequence": { "sequence": "MSSLGGGSQDAGGSSSSTNSSSGSGPKAGGTDKSTTVAAATPASVADDAPPPERRNKSGIISEPLNKSLRRSRPLSHYSSFGSSGGSGSLIGGEPADKAAAAAASLLANGHDLAAAMAVDKSNPTSKHKSGAVASLLSKAERATELAAEGQLTLQQFAQSTEMLKRVVQEHLPLMSEAGAGLPDMEAVASAEALNGQSDFPYLGAFPINPGLFIMTPAGVFLAESALHMAGLAEYPMQGELASAISSGKKKRKRCGMCAPCRRRINCEQCSSCRNRKTGHQICKFRKCEELKKKPSAALEKVMLPTGAAFRWFQ", "length": 314, "header": "tr|A0A8C2MZE7-1|A0A8C2MZE7_CRIGR Isoform 1 of CXXC-type zinc finger protein 5 OS=Cricetulus griseus OX=10029 GN=Cxxc5 PE=4 SV=1 CANONICAL=A0A8C2MZE7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 41, "start_aa": "Thr", "end_pos": 41, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr41", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZE7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"https://www.ebi.ac.uk/QuickGO/term/GO:0043467", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZE7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZE7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZE7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZE7" } ], "pmid": "" }, { "name": "methyl-CpG binding", "id": "GO:0008327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008327", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZE7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZE7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MZE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZE7" }, { "id": "PS51058", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51058" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CXXC-type", "eco_id": "ECO_0000259", "start_pos": 248, "end_pos": 289, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 41 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 19, "end_pos": 21 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273677", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273677" } ] }, { "annotation": "Cadherins are calcium-dependent cell adhesion proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZH6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6#function" }, { "database": "UniProtKB", "id": "RU004357", "url": "https://www.uniprot.org/uniprotkb/RU004357#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZH6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cdh7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6", 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GN=Cdh7 PE=4 SV=1 CANONICAL=A0A8C2MZH6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZH6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZH6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764852", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764852", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BF53-1", "protein_name": "Cadherin 7", "gene_name": "CDH7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLGKVEFCHFLQLISLFLCFSGMSQAELSRSGSKPYFQSGRSRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADIGANAEMDYKIVDGDGLGIFKIAVDKDTQEGIITIQKDLDFEAKTSYTLRIEAANRDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSAPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAVHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKVSAVDKDEPANGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNVMRDTKTRRDVTPEIQFLSRPTFKSIPDNVIFREFIWERLKEADVDPCAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLADMYGNGQESLYS", "length": 785 }, "evidence": [ { "id": "A0A8C2MZH6", "url": "https://omabrowser.org/oma/group/A0A8C2MZH6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1P1D4-1", "protein_name": "Cadherin 7", "gene_name": "CDH7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKLGKVEFCHLLQIIALFLCLSGMNQAEPSRSRSKPYFQSGRTRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGIIKTALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPLASVVARIKAADADVGPNAEMEYKIVDGDGLGVFKISVDKDTQEGIITIQKELDFEAKTSYTLRIEAANMHVDPRFLSLGPFSDMTTVKIIVEDVDEPPVFTSRLYSMVVSEAAKVGTIIGTVAAHDPDASNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAVHNITVLAMESQNPAQIGRGYVAITILDINDNAPEFAMEYETTVCENAQPGQIIQKISAIDKDDPPNGHQFYFSLTAEAANNHNFTLQDNKDNTATVLTRRNGFRRQEQSVFYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGIAQTCNAEAYILPAGLSTGALIAILACVLTLLVLVLLIVTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNIIRDTKTRRDVTPEIQFLSRPTFKSIPDNVIFREFIWERLKEADVDPCAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLADMYGSGPDCLYS", "length": 785 }, "evidence": [ { "id": "A0A8C2MZH6", "url": "https://omabrowser.org/oma/group/A0A8C2MZH6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SMX9-1", "protein_name": "Cadherin 7", "gene_name": "CDH7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"Q5DWV2-1", "protein_name": "Cadherin-7", "gene_name": "Cdh7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLGKVELCRFLQLIALFLCFSGMNQAELPRSRSKPYFQLGRSRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGFIKYILSGEGASSIFIIDENTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNGPESLPVASVVARIKAADADIGVNAEMEYKIVDGDGLGIFKISPDKDTQEGIITIQKELDFEAKTSYTLRIEAANRDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGHIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFNIDANSGIITTAKSLDRETNPVHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAIDKDEPSNGHQFYFSLTTDMANNLNSSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDNGSPSLSSTNTLTIRVCDCDADGIAQTCNAEAYILPAGLSTGALIAILACVLTLLVLILLIVTMKRRKKEPLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNVVRDTKTRRDVTPEIQFLSRPTFKNIPDNVIFREFIWERLKEADVDPGAPPYDSLQTYAFEGNGSVAESLGSLDSNSSNSDQNYDYLSDWGPRFKRLAEMYGNGQESLYS", "length": 785 }, "evidence": [ { "id": "A0A8C2MZH6", "url": "https://omabrowser.org/oma/group/A0A8C2MZH6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BM92-1", "protein_name": "Cadherin-7", "gene_name": "Cdh7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLGKVELCHFLQLIALFLCFSGMSQAELPRSRSKPYFQSGRSRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADIGVNAEMEYKIVDGDGLGIFKISADKDTQEGIITIQKELDFEAKTSYTLRIEAANRDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGHIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAVHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDMTNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGIAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNAIRDSKTRRDVTPEIQFLSRPTFKNIPDNVIFREFIWERLKEADVDPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLAEMYGNGQESLYS", "length": 785 }, "evidence": [ { "id": "A0A8C2MZH6", "url": "https://omabrowser.org/oma/group/A0A8C2MZH6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ULB5-1", "protein_name": "Cadherin-7", "gene_name": "CDH7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLGKVEFCHFLQLIALFLCFSGMSQAELSRSRSKPYFQSGRSRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNVIRDTKTRRDVTPEIQFLSRPAFKSIPDNVIFREFIWERLKEADVDPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLADMYGTGQESLYS", "length": 785 }, "evidence": [ { "id": "A0A8C2MZH6", "url": "https://omabrowser.org/oma/group/A0A8C2MZH6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZH6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6" } ], "pmid": "" }, { "name": "catenin complex", "id": "GO:0016342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016342", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZH6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZH6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZH6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6" } ], "pmid": "" }, { "name": "cell-cell junction assembly", "id": "GO:0007043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007043", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZH6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZH6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6" } ], "pmid": "" }, { "name": "adherens junction organization", "id": "GO:0034332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034332", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZH6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6" } ], "pmid": "" }, { "name": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0016339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016339", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZH6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZH6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZH6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZH6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZH6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 530, "end_pos": 532, "annotation": "n_glycosylation_sequon" }, { "start_pos": 680, "end_pos": 682, "annotation": "n_glycosylation_sequon" }, { "start_pos": 738, "end_pos": 740, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MZH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZH6" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 153, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 449, "end_pos": 451 }, { "start_pos": 530, "end_pos": 532 }, { "start_pos": 680, "end_pos": 682 }, { "start_pos": 738, "end_pos": 740 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MZJ3-1", "uniprot_ac": "A0A8C2MZJ3", "uniprot_id": "A0A8C2MZJ3_CRIGR", "mass": { "chemical_mass": 243161.0, "monoisotopic_mass": 243161.0 }, "refseq": { "ac": "XP_027269968", "name": "mediator of RNA polymerase II transcription subunit 13-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269968" }, "gene_names": [ { "name": "Med13l", "type": "recommended", "evidence": [ { "id": "A0A8C2MZJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZJ3" } ] }, { "name": "Med13l", "type": "synonym", "evidence": [ { "id": "XP_027269968", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269968" } ] } ], "protein_names": [ { "name": "Mediator of RNA polymerase II transcription subunit 13", "type": "recommended", "evidence": [ { "id": "A0A8C2MZJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZJ3/entry#names_and_taxonomy" } ] }, { "name": "mediator of RNA polymerase II transcription subunit 13-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027269968", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269968" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269968", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269968" } ] }, { "annotation": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWP0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWP0#function" }, { "database": "UniProtKB", "id": "RU364134", "url": "https://www.uniprot.org/uniprotkb/RU364134#function" }, { "database": "UniProtKB", "id": "A0A9J7JH82", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH82#function" }, { "database": "UniProtKB", "id": "A0A9J7JLY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLY2#function" }, { "database": "UniProtKB", "id": "A0A9J7JPU2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPU2#function" }, { "database": "UniProtKB", "id": "A0A8C2MZJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZJ3#function" }, { "database": "UniProtKB", "id": "A0A9J7GXK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXK2#function" }, { "database": "UniProtKB", "id": "A0A9J7GXY4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXY4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZJ3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Med13l", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZJ3", "locus": {} } ], "crossref": [ { "id": "100757555", "url": "https://www.ncbi.nlm.nih.gov/gene/100757555", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041285", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041285", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757555", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757555", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MZJ3", "url": "https://www.orthodb.org/?gene=A0A8C2MZJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48249", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48249", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48249:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48249:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06333", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06333", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11597", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11597", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18296", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18296", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269968", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269968", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWP0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXY4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JH82", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JH82-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPU2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAAANWVANGASLEDCHSNLFSLAELTGIKWRRYNFGGHGDCGPIISAPAQDDPILLSFIRCLQANLLCVWRRDVKPDCKELWIFWWGDEPNLVGVIHHELQVVEEGLWENGLSYECRTLLFKAIHNLLERCLMDKNFVRIGKWFVRPYDKDEKPVNKSEHLSCAFTFFLHGESNVCTSVEIAQHQPIYLISEEHLHMAQSSPAPFQVLVSPYGLNGTLTGHAYKMSDPATRKLIEEWQYFYPMVLRKKEESREEAELGYDDDFPVAVEVIVGGVRMVYPSAFVLISQNDIPVPQSTASVGGHISVAQQGLGSVKDPSNCGMPLTPPTSPEQVVIGESGGMQSAASHLSSQDGGMITMHSPKRSRKIPPKLHNHMVHRVWKECILNRAQSKRSQVSTPTQEEEPAHNPAAWDFVDPTQRVSCSCSRHKLLKRCTVGPSRPPTVSQPGFSTGPPSSSSLPPPASSKHKTAERQEKGDKLQKRPLVPFHHRPSVAEELCMEQDASGQKLGLAGIDASLEVSSSRKYDKQMAVPSRNTSKQLNLNPMDSPHSPISPLPPTLSPQPRGQEAESLDPPSVPVNSALYGNGLELQQLSTLDDRTVLVGQRLPLMAEVSETALYSGIRPSYTESSDKWWQGFRLPSSEDAEFRPPELQGDRFDIKLDVNPESTALQRLLAQPNKRFKIWQDEQPQVQPLPFLDPSPLSQQPGDALGEVNDPYTFEDGDIKYIFTANKKCKQGTEKDTLKKNKSEDGFGTKDVTTPGHSTPVPDGKNAMSIFSSATKTDVRQDNAAGRAGSGSLTQVTDLAPSLHDLDNIFDNSDDDELGAVSPALRSSKMTAVGTEERPPGKDGRSAGPYPPTVADLQRMFPTPPSLEQHPAFSPVMNYKDGVSSETVTALGMMESPVVSMVPTHFTEFRMEVEDGLGSPKPEEIKDFSYVHKVPQFQPFVGSSMFAPLKTLPSHCLLPLKTPDACLFRPSWAVPPKMEQLPMPPAAASIRDGYNNVPSVGSLADPDYLNTPQMNTPVTLNSTAPASNSGAGVLPSPATPRFSVPTPRTPRTPRTPRGGGTASGQGSVKYDSTDQGSPASTPSTTRPLNSVEPATMQPIPEAHSLYVTLILSDSVMNVFKDRNFDSCCICACNMNIKGADVGLYIPDSSKEDQYRCTCGFSAIMNRKLGYNSGLFLEDELDIFGKNSDIGQAAERRLMMCQSTFLPQMEGARKSPEPPISLLLLLQNQHTQPFASLSFLDYISSNSRHALPCVSWTYDRVQADNNDYWTECFNALEQGRQYVDNPTGGKVDEALVRSATVHCWPHSNVLDTSMLSSQDVVRMLLSLQPFLQDAIQKKRTGRTWENIQHVQGPLTWQQFHKMAGRGTYGSEESPEPLPIPTLLVGYDKEFLTISPFSLPFWERLLLEPYGGHRDVAYIVVCPENEALLEGAKTFFRDLSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQKLTEELVSEWFNQPWSSEENDNHSRLKLYAQVCRHHLAPYLATLQLDSGLLMPPKHQSPPAEAQGQATPGNAGSLPSSAGSVAPPAGSSFNPTSNSSANPAASSSSASSGPPGSSTASASGITQMNTTSSSGFSGGVGGQNPNTGGSSADRAPGNVACGDTEPGQSSAQPSQDGQDSVTERERIGIPTEPDSADSHAYPPAVVIYMVDPFTYTAEEDSSSGNFWLLSLMRCYTEMLDHLPEHMRSSFILQIVPCQYMLQTMKDEHVFYIQYLKSMAFSVYCQCRRPLPTQIHIKSLTGFGPAASIEMTLKNPERPSPIQLYSPPFILAPIKDKQTEPGETFGEASQKYNVLFVGYCLSHDQRWLLASCTDLHGELLETCVVNIALPSRTLPVSVSVRSRKSKVSARKIGLQKLWEWCLGIVQMTSLPWRVVIGRLGRLGHGELKDWSILLGECSLQTISKQLKDVCRMCGISAADSPSILSACLVAMEPQGSFVVMPDAVTMGSVFGRSTALNMQSSQLNTPQDASCTHILVFPTSSTIQVAPANYPNEDGFSPNNDDMFVDLPFPDDMDNDIGILMTGNLHSSPNSSPVPSPGSPSGIGVGSHFQHSRSQGERLLSREAPEELKQQPLALGYFVSTAKAENLPQWFWSSCPQARNQCPLFLKASLHHHISVAQTDELLPARTSQRAPHPLDSKTTSDVLRFVLEQYNALSWLTCNPATQDRTSCLPVHFVVLTQLYNAIMNML", "length": 2217, "header": "tr|A0A8C2MZJ3-1|A0A8C2MZJ3_CRIGR Isoform 1 of Mediator of RNA polymerase II transcription subunit 13 OS=Cricetulus griseus OX=10029 GN=Med13l PE=3 SV=1 CANONICAL=A0A8C2MZJ3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZJ3/entry#A0A8C2MZJ3-1", "sequence": { "sequence": "MTAAANWVANGASLEDCHSNLFSLAELTGIKWRRYNFGGHGDCGPIISAPAQDDPILLSFIRCLQANLLCVWRRDVKPDCKELWIFWWGDEPNLVGVIHHELQVVEEGLWENGLSYECRTLLFKAIHNLLERCLMDKNFVRIGKWFVRPYDKDEKPVNKSEHLSCAFTFFLHGESNVCTSVEIAQHQPIYLISEEHLHMAQSSPAPFQVLVSPYGLNGTLTGHAYKMSDPATRKLIEEWQYFYPMVLRKKEESREEAELGYDDDFPVAVEVIVGGVRMVYPSAFVLISQNDIPVPQSTASVGGHISVAQQGLGSVKDPSNCGMPLTPPTSPEQVVIGESGGMQSAASHLSSQDGGMITMHSPKRSRKIPPKLHNHMVHRVWKECILNRAQSKRSQVSTPTQEEEPAHNPAAWDFVDPTQRVSCSCSRHKLLKRCTVGPSRPPTVSQPGFSTGPPSSSSLPPPASSKHKTAERQEKGDKLQKRPLVPFHHRPSVAEELCMEQDASGQKLGLAGIDASLEVSSSRKYDKQMAVPSRNTSKQLNLNPMDSPHSPISPLPPTLSPQPRGQEAESLDPPSVPVNSALYGNGLELQQLSTLDDRTVLVGQRLPLMAEVSETALYSGIRPSYTESSDKWWQGFRLPSSEDAEFRPPELQGDRFDIKLDVNPESTALQRLLAQPNKRFKIWQDEQPQVQPLPFLDPSPLSQQPGDALGEVNDPYTFEDGDIKYIFTANKKCKQGTEKDTLKKNKSEDGFGTKDVTTPGHSTPVPDGKNAMSIFSSATKTDVRQDNAAGRAGSGSLTQVTDLAPSLHDLDNIFDNSDDDELGAVSPALRSSKMTAVGTEERPPGKDGRSAGPYPPTVADLQRMFPTPPSLEQHPAFSPVMNYKDGVSSETVTALGMMESPVVSMVPTHFTEFRMEVEDGLGSPKPEEIKDFSYVHKVPQFQPFVGSSMFAPLKTLPSHCLLPLKTPDACLFRPSWAVPPKMEQLPMPPAAASIRDGYNNVPSVGSLADPDYLNTPQMNTPVTLNSTAPASNSGAGVLPSPATPRFSVPTPRTPRTPRTPRGGGTASGQGSVKYDSTDQGSPASTPSTTRPLNSVEPATMQPIPEAHSLYVTLILSDSVMNVFKDRNFDSCCICACNMNIKGADVGLYIPDSSKEDQYRCTCGFSAIMNRKLGYNSGLFLEDELDIFGKNSDIGQAAERRLMMCQSTFLPQMEGARKSPEPPISLLLLLQNQHTQPFASLSFLDYISSNSRHALPCVSWTYDRVQADNNDYWTECFNALEQGRQYVDNPTGGKVDEALVRSATVHCWPHSNVLDTSMLSSQDVVRMLLSLQPFLQDAIQKKRTGRTWENIQHVQGPLTWQQFHKMAGRGTYGSEESPEPLPIPTLLVGYDKEFLTISPFSLPFWERLLLEPYGGHRDVAYIVVCPENEALLEGAKTFFRDLSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQKLTEELVSEWFNQPWSSEENDNHSRLKLYAQVCRHHLAPYLATLQLDSGLLMPPKHQSPPAEAQGQATPGNAGSLPSSAGSVAPPAGSSFNPTSNSSANPAASSSSASSGPPGSSTASASGITQMNTTSSSGFSGGVGGQNPNTGGSSADRAPGNVACGDTEPGQSSAQPSQDGQDSVTERERIGIPTEPDSADSHAYPPAVVIYMVDPFTYTAEEDSSSGNFWLLSLMRCYTEMLDHLPEHMRSSFILQIVPCQYMLQTMKDEHVFYIQYLKSMAFSVYCQCRRPLPTQIHIKSLTGFGPAASIEMTLKNPERPSPIQLYSPPFILAPIKDKQTEPGETFGEASQKYNVLFVGYCLSHDQRWLLASCTDLHGELLETCVVNIALPSRTLPVSVSVRSRKSKVSARKIGLQKLWEWCLGIVQMTSLPWRVVIGRLGRLGHGELKDWSILLGECSLQTISKQLKDVCRMCGISAADSPSILSACLVAMEPQGSFVVMPDAVTMGSVFGRSTALNMQSSQLNTPQDASCTHILVFPTSSTIQVAPANYPNEDGFSPNNDDMFVDLPFPDDMDNDIGILMTGNLHSSPNSSPVPSPGSPSGIGVGSHFQHSRSQGERLLSREAPEELKQQPLALGYFVSTAKAENLPQWFWSSCPQARNQCPLFLKASLHHHISVAQTDELLPARTSQRAPHPLDSKTTSDVLRFVLEQYNALSWLTCNPATQDRTSCLPVHFVVLTQLYNAIMNML", "length": 2217, "header": "tr|A0A8C2MZJ3-1|A0A8C2MZJ3_CRIGR Isoform 1 of Mediator of RNA polymerase II transcription subunit 13 OS=Cricetulus griseus OX=10029 GN=Med13l PE=3 SV=1 CANONICAL=A0A8C2MZJ3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FWP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZJ3/entry#A0A9J7FWP0-1", "sequence": { "sequence": "MTAAANWVANGASLEDCHSNLFSLAELTGIKWRRYNFGGHGDCGPIISAPAQDDPILLSFIRCLQANLLCVWRRDVKPDCKELWIFWWGDEPNLVGVIHHELQVVEEGLWENGLSYECRTLLFKAIHNLLERCLMDKNFVRIGKWFVRPYDKDEKPVNKSEHLSCAFTFFLHGESNVCTSVEIAQHQPIYLISEEHLHMAQSSPAPFQVLVSPYGLNGTLTGHAYKMSDPATRKLIEEWQYFYPMVLRKKEESREEAELGYDDDFPVAVEVIVGGVRMVYPSAFVLISQNDIPVPQSTASVGGHISVAQQGLGSVKDPSNCGMPLTPPTSPEQVVIGESGGMQSAASHLSSQDGGMITMHSPKRSRKIPPKLHNHMVHRVWKECILNRAQSKRSQVSTPTQEEEPAHNPAAWDFVDPTQRVSCSCSRHKLLKRCTVGPSRPPTVSQPGFSTGPPSSSSLPPPASSKHKTAERQEKGDKLQKRPLVPFHHRPSVAEELCMEQDASGQKLGLAGIDASLEVSSSRKYDKQMAVPSRNTSKQLNLNPMDSPHSPISPLPPTLSPQPRGQEAESLDPPSVPVNSALYGNGLELQQLSTLDDRTVLVGQRLPLMAEVSETALYSGIRPSYTESSDKWWQGFRLPSSEDAEFRPPELQGDRFDIKLDVNPESTALQRLLAQPNKRFKIWQDEQPQVQPLPFLDPSPLSQQPGDALGEVNDPYTFEDGDIKYIFTANKKCKQGTEKDTLKKNKSEDGFGTKDVTTPGHSTPVPDGKNAMSIFSSATKTDVRQDNAAGRAGSGSLTQVTDLAPSLHDLDNIFDNSDDDELGAVSPALRSSKMTAVGTEERPPGKDGRSAGPYPPTVADLQRMFPTPPSLEQHPAFSPVMNYKDGVSSETVTALGMMESPVVSMVPTHFTEFRMEVEDGLGSPKPEEIKDFSYVHKVPQFQPFVGSSMFAPLKTLPSHCLLPLKTPDACLFRPSWAVPPKMEQLPMPPAAASIRDGYNNVPSVGSLADPDYLNTPQMNTPVTLNSTAPASNSGAGVLPSPATPRFSVPTPRTPRTPRTPRGGGTASGQGSVKYDSTDQGSPASTPSTTRPLNSVEPATMQPIPEAHSLYVTLILSDSVMNVFKDRNFDSCCICACNMNIKGADVGLYIPDSSKEDQYRCTCGFSAIMNRKLGYNSGLFLEDELDIFGKNSDIGQAAERRLMMCQSTFLPQMEGARKSPEPPISLLLLLQNQHTQPFASLSFLDYISSNSRHALPCVSWTYDRVQADNNDYWTECFNALEQGRQYVDNPTGGKVDEALVRSATVHCWPHSNVLDTSMLSSQDVVRMLLSLQPFLQDAIQKKRTGRTWENIQHVQGPLTWQQFHKMAGRGTYGSEESPEPLPIPTLLVGYDKEFLTISPFSLPFWERLLLEPYGGHRDVAYIVVCPENEALLEGAKTFFRDLSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQKLTEELVSEWFNQPWSSEENDNHSRLKLYAQVCRHHLAPYLATLQLDSGLLMPPKHQSPPAEAQGQATPGNAGSLPSSAGSVAPPAGSSFNPTSNSSANPAASSSSASSGPPGSSTASASGITQMNTTSSSGFSGGVGGQNPNTGGSSADRAPGNVACGDTEPGQSSAQPSQDGQDSVTERERIGIPTEPDSADSHAYPPAVVIYMVDPFTYTAEEDSSSGNFWLLSLMRCYTEMLDHLPEHMRSSFILQIVPCQYMLQTMKDEHVFYIQYLKSMAFSVYCQCRRPLPTQIHIKSLTGFGPAASIEMTLKNPERPSPIQLYSPPFILAPIKDKQTEPGETFGEASQKYNVLFVGYCLSHDQRWLLASCTDLHGELLETCVVNIALPSRSRKSKVSARKIGLQKLWEWCLGIVQMTSLPWRVVIGRLGRLGHGELKDWSILLGECSLQTISKQLKDVCRMCGISAADSPSILSACLVAMEPQGSFVVMPDAVTMGSVFGRSTALNMQSSQLNTPQDASCTHILVFPTSSTIQVAPANYPNEDGFSPNNDDMFVDLPFPDDMDNDIGILMTGNLHSSPNSSPVPSPGSPSGIGVGSHFQHSRSQGERLLSREAPEELKQQPLALGYFVSTAKAENLPQWFWSSCPQARNQCPLFLKASLHHHISVAQTDELLPARTSQRAPHPLDSKTTSDVLRFVLEQYNALSWLTCNPATQDRTSCLPVHFVVLTQLYNAIMNML", "length": 2208, "header": "tr|A0A9J7FWP0-1|A0A8C2MZJ3_CRIGR Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 13 OS=Cricetulus griseus OX=10029 GN=Med13l PE=3 SV=1 CANONICAL=A0A8C2MZJ3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GXK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZJ3/entry#A0A9J7GXK2-1", "sequence": { "sequence": "MTAAANWVANGASLEDCHSNLFSLAELTGIKWRRYNFGGHGDCGPIISAPAQDDPILLSFIRCLQANLLCVWRRDVKPDCKELWIFWWGDEPNLVGVIHHELQVVEEGLWENGLSYECRTLLFKAIHNLLERCLMDKNFVRIGKWFVRPYDKDEKPVNKSEHLSCAFTFFLHGESNVCTSVEIAQHQPIYLISEEHLHMAQSSPAPFQVLVSPYGLNGTLTGHAYKMSDPATRKLIEEWQYFYPMVLRKKEESREEAELGYDDDFPVAVEVIVGGVRMVYPSAFVLISQNDIPVPQSTASVGGHISVAQQGLGSVKDPSNCGMPLTPPTSPEQVVIGESGGMQSAASHLSSQDGGMITMHSPKRSRKIPPKLHNHMVHRVWKECILNRAQSKRSQVSTPTQEEEPAHNPAAWDFVDPTQRVSCSCSRHKLLKRCTVGPSRPPTVSQPGFSTGPPSSSSLPPPASSKHKTAERQEKGDKLQKRPLVPFHHRPSVAEELCMEQDASGQKLGLAGIDASLEVSSSRKYDKQMAVPSRNTSKQLNLNPMDSPHSPISPLPPTLSPQPRGQEAESLDPPSVPVNSALYGNGLELQQLSTLDDRTVLVGQRLPLMAEVSETALYSGIRPSYTESSDKWWQGFRLPSSEDAEFRPPELQGDRFDIKLDVNPESTALQRLLAQPNKRFKIWQDEQPQVQPLPFLDPSPLSQQPGDALGEVNDPYTFEDGDIKYIFTANKKCKQGTEKDTLKKNKSEDGFGTKDVTTPGHSTPVPDGKNAMSIFSSATKTDVRQDNAAGRAGSGSLTQVTDLAPSLHDLDNIFDNSDDDELGAVSPALRSSKMTAVGTEERPPGKDGRSAGPYPPTVADLQRMFPTPPSLEQHPAFSPVMNYKDGVSSETVTALGMMESPVVSMVPTHFTEFRMEVEDGLGSPKPEEIKDFSYVHKVPQFQPFVGSSMFAPLKTLPSHCLLPLKTPDACLFRPSWAVPPKMEQLPMPPAAASIRDGYNNVPSVGSLADPDYLNTPQMNTPVTLNSTAPASNSGAGVLPSPATPRFSVPTPRTPRTPRTPRGGGTASGQGSVKYDSTDQGSPASTPSTTRPLNSVEPATMQPIPEAHSLYVTLILSDSVMNVFKDRNFDSCCICACNMNIKGADVGLYIPDSSKEDQYRCTCGFSAIMNRKLGYNSGLFLEDELDIFGKNSDIGQAAERRLMMCQSTFLPQMEGARKSPEPPISLLLLLQNQHTQPFASLSFLDYISSNSRHALPCVSWTYDRVQADNNDYWTECFNALEQGRQYVDNPTGGKVDEALVRSATVHCWPHSNVLDTSMLSSQDVVRMLLSLQPFLQDAIQKKRTGRTWENIQHVQGPLTWQQFHKMAGRGTYGSEESPEPLPIPTLLVGYDKEFLTISPFSLPFWERLLLEPYGGHRDVAYIVVCPENEALLEGAKTFFRDLSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQKLTEELVSEWFNQPWSSEENDNHSRLKLYAQVCRHHLAPYLATLQLDSGLLMPPKHQSPPAEAQGQATPGNAGSLPSSAGSVAPPAGSSFNPTSNSSANPAASSSSASSGPPGSSTASASGITQMNTTSSSGFSGGVGGQNPNTGGSSADRAPGNVACGDTEPGQSSAQPSQDGQDSVTERERIGIPTEPDSADSHAYPPAVVIYMVDPFTYTAEEDSSSGNFWLLSLMRCYTEMLDHLPEHMRSSFILQIVPCQYMLQTMKDEHVFYIQYLKSMAFSVYCQCRRPLPTQIHIKSLTGFGPAASIEMTLKNPERPSPIQLYSPPFILAPIKDKQTEPGETFGEASQKYNVLFVGYCLSHDQRWLLASCTDLHGELLETCVVNIALPSRTLPVSVSVRSRKSKVSARKIGLQKLWEWCLGIVQMTSLPWRVVIGRLGRLGHGELKDWSILLGECSLQTISKQLKDVCRMCGISAADSPSILSACLVAMEPQGSFVVMPGHLRNWGSLECLSLRLCIRGEPPSGDVVCRAH", "length": 2002, "header": "tr|A0A9J7GXK2-1|A0A9J7GXK2_CRIGR Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 13 OS=Cricetulus griseus OX=10029 GN=Med13l PE=3 SV=1 CANONICAL=A0A8C2MZJ3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GXY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZJ3/entry#A0A9J7GXY4-1", "sequence": { "sequence": "MDLRCLMDKNFVRIGKWFVRPYDKDEKPVNKSEHLSCAFTFFLHGESNVCTSVEIAQHQPIYLISEEHLHMAQSSPAPFQVLVSPYGLNGTLTGHAYKMSDPATRKLIEEWQYFYPMVLRKKEESREEAELGYDDDFPVAVEVIVGGVRMVYPSAFVLISQNDIPVPQSTASVGGHISVAQQGLGSVKDPSNCGMPLTPPTSPEQVVIGESGGMQSAASHLSSQDGGMITMHSPKRSRKIPPKLHNHMVHRVWKECILNRAQSKRSQVSTPTQEEEPAHNPAAWDFVDPTQRVSCSCSRHKLLKRCTVGPSRPPTVSQPGFSTGPPSSSSLPPPASSKHKTAERQEKGDKLQKRPLVPFHHRPSVAEELCMEQDASGQKLGLAGIDASLEVSSSRKYDKQMAVPSRNTSKQLNLNPMDSPHSPISPLPPTLSPQPRGQEAESLDPPSVPVNSALYGNGLELQQLSTLDDRTVLVGQRLPLMAEVSETALYSGIRPSYTESSDKWWQGFRLPSSEDAEFRPPELQGDRFDIKLDVNPESTALQRLLAQPNKRFKIWQDEQPQVQPLPFLDPSPLSQQPGDALGEVNDPYTFEDGDIKYIFTANKKCKQGTEKDTLKKNKSEDGFGTKDVTTPGHSTPVPDGKNAMSIFSSATKTDVRQDNAAGRAGSGSLTQVTDLAPSLHDLDNIFDNSDDDELGAVSPALRSSKMTAVGTEERPPGKDGRSAGPYPPTVADLQRMFPTPPSLEQHPAFSPVMNYKDGVSSETVTALGMMESPVVSMVPTHFTEFRMEVEDGLGSPKPEEIKDFSYVHKVPQFQPFVGSSMFAPLKTLPSHCLLPLKTPDACLFRPSWAVPPKMEQLPMPPAAASIRDGYNNVPSVGSLADPDYLNTPQMNTPVTLNSTAPASNSGAGVLPSPATPRFSVPTPRTPRTPRTPRGGGTASGQGSVKYDSTDQGSPASTPSTTRPLNSVEPATMQPIPEAHSLYVTLILSDSVMNVFKDRNFDSCCICACNMNIKGADVGLYIPDSSKEDQYRCTCGFSAIMNRKLGYNSGLFLEDELDIFGKNSDIGQAAERRLMMCQSTFLPQMEGARKSPEPPISLLLLLQNQHTQPFASLSFLDYISSNSRHALPCVSWTYDRVQADNNDYWTECFNALEQGRQYVDNPTGGKVDEALVRSATVHCWPHSNVLDTSMLSSQDVVRMLLSLQPFLQDAIQKKRTGRTWENIQHVQGPLTWQQFHKMAGRGTYGSEESPEPLPIPTLLVGYDKEFLTISPFSLPFWERLLLEPYGGHRDVAYIVVCPENEALLEGAKTFFRDLSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQKLTEELVSEWFNQPWSSEENDNHSRLKLYAQVCRHHLAPYLATLQLDSGLLMPPKHQSPPAEAQGQATPGNAGSLPSSAGSVAPPAGSSFNPTSNSSANPAASSSSASSGPPGSSTASASGITQMNTTSSSGFSGGVGGQNPNTGGSSADRAPGNVACGDTEPGQSSAQPSQDGQDSVTERERIGIPTEPDSADSHAYPPAVVIYMVDPFTYTAEEDSSSGNFWLLSLMRCYTEMLDHLPEHMRSSFILQIVPCQYMLQTMKDEHVFYIQYLKSMAFSVYCQCRRPLPTQIHIKSLTGFGPAASIEMTLKNPERPSPIQLYSPPFILAPIKDKQTEPGETFGEASQKYNVLFVGYCLSHDQRWLLASCTDLHGELLETCVVNIALPSRTLPVSVSVRSRKSKVSARKIGLQKLWEWCLGIVQMTSLPWRVVIGRLGRLGHGELKDWSILLGECSLQTISKQLKDVCRMCGISAADSPSILSACLVAMEPQGSFVVMPDAVTMGSVFGRSTALNMQSSQLNTPQDASCTHILVFPTSSTIQVAPANYPNEDGFSPNNDDMFVDLPFPDDMDNDIGILMTGNLHSSPNSSPVPSPGSPSGIGVGSHFQHSRSQGERLLSREAPEELKQQPLALGYFVSTAKAENLPQWFWSSCPQARNQCPLFLKASLHHHISVAQTDELLPARTSQRAPHPLDSKTTSDVLRFVLEQYNALSWLTCNPATQDRTSCLPVHFVVLTQLYNAIMNML", "length": 2089, "header": "tr|A0A9J7GXY4-1|A0A9J7GXY4_CRIGR Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 13 OS=Cricetulus griseus OX=10029 GN=Med13l PE=3 SV=1 CANONICAL=A0A8C2MZJ3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JH82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZJ3/entry#A0A9J7JH82-1", "sequence": { "sequence": "MDKNFVRIGKWFVRPYDKDEKPVNKSEHLSCAFTFFLHGESNVCTSVEIAQHQPIYLISEEHLHMAQSSPAPFQVLVSPYGLNGTLTGHAYKMSDPATRKLIEEWQYFYPMVLRKKEESREEAELGYDDDFPVAVEVIVGGVRMVYPSAFVLISQNDIPVPQSTASVGGHISVAQQGLGSVKDPSNCGMPLTPPTSPEQVVIGESGGMQSAASHLSSQDGGMITMHSPKRSRKIPPKLHNHMVHRVWKECILNRAQSKRSQVSTPTQEEEPAHNPAAWDFVDPTQRVSCSCSRHKLLKRCTVGPSRPPTVSQPGFSTGPPSSSSLPPPASSKHKTAERQEKGDKLQKRPLVPFHHRPSVAEELCMEQDASGQKLGLAGIDASLEVSSSRKYDKQMAVPSRNTSKQLNLNPMDSPHSPISPLPPTLSPQPRGQEAESLDPPSVPVNSALYGNGLELQQLSTLDDRTVLVGQRLPLMAEVSETALYSGIRPSYTESSDKWWQGFRLPSSEDAEFRPPELQGDRFDIKLDVNPESTALQRLLAQPNKRFKIWQDEQPQVQPLPFLDPSPLSQQPGDALGEVNDPYTFEDGDIKYIFTANKKCKQGTEKDTLKKNKSEDGFGTKDVTTPGHSTPVPDGKNAMSIFSSATKTDVRQDNAAGRAGSGSLTQVTDLAPSLHDLDNIFDNSDDDELGAVSPALRSSKMTAVGTEERPPGKDGRSAGPYPPTVADLQRMFPTPPSLEQHPAFSPVMNYKDGVSSETVTALGMMESPVVSMVPTHFTEFRMEVEDGLGSPKPEEIKDFSYVHKVPQFQPFVGSSMFAPLKTLPSHCLLPLKTPDACLFRPSWAVPPKMEQLPMPPAAASIRDGYNNVPSVGSLADPDYLNTPQMNTPVTLNSTAPASNSGAGVLPSPATPRFSVPTPRTPRTPRTPRGGGTASGQGSVKYDSTDQGSPASTPSTTRPLNSVEPATMQPIPEAHSLYVTLILSDSVMNVFKDRNFDSCCICACNMNIKGADVGLYIPDSSKEDQYRCTCGFSAIMNRKLGYNSGLFLEDELDIFGKNSDIGQAAERRLMMCQSTFLPQMEGARKSPEPPISLLLLLQNQHTQPFASLSFLDYISSNSRHALPCVSWTYDRVQADNNDYWTECFNALEQGRQYVDNPTGGKVDEALVRSATVHCWPHSNVLDTSMLSSQDVVRMLLSLQPFLQDAIQKKRTGRTWENIQHVQGPLTWQQFHKMAGRGTYGSEESPEPLPIPTLLVGYDKEFLTISPFSLPFWERLLLEPYGGHRDVAYIVVCPENEALLEGAKTFFRDLSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQKLTEELVSEWFNQPWSSEENDNHSRLKLYAQVCRHHLAPYLATLQLDSGLLMPPKHQSPPAEAQGQATPGNAGSLPSSAGSVAPPAGSSFNPTSNSSANPAASSSSASSGPPGSSTASASGITQMNTTSSSGFSGGVGGQNPNTGGSSADRAPGNVACGDTEPGQSSAQPSQDGQDSVTERERIGIPTEPDSADSHAYPPAVVIYMVDPFTYTAEEDSSSGNFWLLSLMRCYTEMLDHLPEHMRSSFILQIVPCQYMLQTMKDEHVFYIQYLKSMAFSVYCQCRRPLPTQIHIKSLTGFGPAASIEMTLKNPERPSPIQLYSPPFILAPIKDKQTEPGETFGEASQKYNVLFVGYCLSHDQRWLLASCTDLHGELLETCVVNIALPSRTLPVSVSVRSRKSKVSARKIGLQKLWEWCLGIVQMTSLPWRVVIGRLGRLGHGELKDWSILLGECSLQTISKQLKDVCRMCGISAADSPSILSACLVAMEPQGSFVVMPDAVTMGSVFGRSTALNMQSSQLNTPQDASCTHILVFPTSSTIQVAPANYPNEDGFSPNNDDMFVDLPFPDDMDNDIGILMTGNLHSSPNSSPVPSPGSPSGIGVGSHFQHSRSQGERLLSREAPEELKQQPLALGYFVSTAKAENLPQWFWSSCPQARNQCPLFLKASLHHHISVAQTDELLPARTSQRAPHPLDSKTTSDVLRFVLEQYNALSWLTCNPATQDRTSCLPVHFVVLTQLYNAIMNML", "length": 2083, "header": "tr|A0A9J7JH82-1|A0A8C2MZJ3_CRIGR Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 13 OS=Cricetulus griseus OX=10029 GN=Med13l PE=3 SV=1 CANONICAL=A0A8C2MZJ3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JLY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZJ3/entry#A0A9J7JLY2-1", "sequence": { "sequence": "MTAAANWVANGASLEDCHSNLFSLAELTGIKWRRYNFGGHGDCGPIISAPAQDDPILLSFIRCLQANLLCVWRRDVKPDCKELWIFWWGDEPNLVGVIHHELQVVEEGLWENGLSYECRTLLFKAIHNLLERCLMDKNFVRIGKWFVRPYDKDEKPVNKSEHLSCAFTFFLHGESNVCTSVEIAQHQPIYLISEEHLHMAQSSPAPFQVLVSPYGLNGTLTGHAYKMSDPATRKLIEEWQYFYPMVLRKKEESREEAELGYDDDFPVAVEVIVGGVRMVYPSAFVLISQNDIPVPQSTASVGGHISVAQQGLGSVKDPSNCGMPLTPPTSPEQVVIGESGGMQSAASHLSSQDGGMITMHSPKRSRKIPPKLHNHMVHRVWKECILNRAQSKRSQVSTPTQEEEPAHNPAAWDFVDPTQRVSCSCSRHKLLKRCTVGPSRPPTVSQPGFSTGPPSSSSLPPPASSKHKTAERQEKGDKLQKRPLVPFHHRPSVAEELCMEQDASGQKLGLAGIDASLEVSSSRKYDKQMAVPSRNTSKQLNLNPMDSPHSPISPLPPTLSPQPRGQEAESLDPPSVPVNSALYGNGLELQQLSTLDDRTVLVGQRLPLMAEVSETALYSGIRPSYTESSDKWWQGFRLPSSEDAEFRPPELQGDRFDIKLDVNPESTALQRLLAQPNKRFKIWQDEQPQVQPLPFLDPSPLSQQPGDALGEVNDPYTFEDGDIKYIFTANKKCKQGTEKDTLKKNKSEDGFGTKDVTTPGHSTPVPDGKNAMSIFSSATKTDVRQDNAAGRAGSGSLTQVTDLAPSLHDLDNIFDNSDDDELGAVSPALRSSKMTAVGTEERPPGKDGRSAGPYPPIADLQRMFPTPPSLEQHPAFSPVMNYKDGVSSETVTALGMMESPVVSMVPTHFTEFRMEVEDGLGSPKPEEIKDFSYVHKVPQFQPFVGSSMFAPLKTLPSHCLLPLKTPDACLFRPSWAVPPKMEQLPMPPAAASIRDGYNNVPSVGSLADPDYLNTPQMNTPVTLNSTAPASNSGAGVLPSPATPRFSVPTPRTPRTPRTPRGGGTASGQGSVKYDSTDQGSPASTPSTTRPLNSVEPATMQPIPEAHSLYVTLILSDSVMNVFKDRNFDSCCICACNMNIKGADVGLYIPDSSKEDQYRCTCGFSAIMNRKLGYNSGLFLEDELDIFGKNSDIGQAAERRLMMCQSTFLPQMEGARKSPEPPISLLLLLQNQHTQPFASLSFLDYISSNSRHALPCVSWTYDRVQADNNDYWTECFNALEQGRQYVDNPTGGKVDEALVRSATVHCWPHSNVLDTSMLSSQDVVRMLLSLQPFLQDAIQKKRTGRTWENIQHVQGPLTWQQFHKMAGRGTYGSEESPEPLPIPTLLVGYDKEFLTISPFSLPFWERLLLEPYGGHRDVAYIVVCPENEALLEGAKTFFRDLSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQKLTEELVSEWFNQPWSSEENDNHSRLKLYAQVCRHHLAPYLATLQLDSGLLMPPKHQSPPAEAQGQATPGNAGSLPSSAGSVAPPAGSSFNPTSNSSANPAASSSSASSGPPGSSTASASGITQMNTTSSSGFSGGVGGQNPNTGGSSADRAPGNVACGDTEPGQSSAQPSQDGQDSVTERERIGIPTEPDSADSHAYPPAVVIYMVDPFTYTAEEDSSSGNFWLLSLMRCYTEMLDHLPEHMRSSFILQIVPCQYMLQTMKDEHVFYIQYLKSMAFSVYCQCRRPLPTQIHIKSLTGFGPAASIEMTLKNPERPSPIQLYSPPFILAPIKDKQTEPGETFGEASQKYNVLFVGYCLSHDQRWLLASCTDLHGELLETCVVNIALPSRTLPVSVSVRSRKSKVSARKIGLQKLWEWCLGIVQMTSLPWRVVIGRLGRLGHGELKDWSILLGECSLQTISKQLKDVCRMCGISAADSPSILSACLVAMEPQGSFVVMPDAVTMGSVFGRSTALNMQSSQLNTPQDASCTHILVFPTSSTIQVAPANYPNEDGFSPNNDDMFVDLPFPDDMDNDIGILMTGNLHSSPNSSPVPSPGSPSGIGVGSHFQHSRSQGERLLSREAPEELKQQPLALGYFVSTAKAENLPQWFWSSCPQARNQCPLFLKASLHHHISVAQTDELLPARTSQRAPHPLDSKTTSDVLRFVLEQYNALSWLTCNPATQDRTSCLPVHFVVLTQLYNAIMNML", "length": 2216, "header": "tr|A0A9J7JLY2-1|A0A8C2MZJ3_CRIGR Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 13 OS=Cricetulus griseus OX=10029 GN=Med13l PE=3 SV=1 CANONICAL=A0A8C2MZJ3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JPU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZJ3/entry#A0A9J7JPU2-1", "sequence": { "sequence": "MTAAANWVANGASLEDCHSNLFSLAELTGIKWRRYNFGGHGDCGPIISAPAQDDPILLSFIRCLQANLLCVWRRDVKPDCKELWIFWWGDEPNLVGVIHHELQVVEEGLWENGLSYECRTLLFKAIHNLLERCLMDKNFVRIGKWFVRPYDKDEKPVNKSEHLSCAFTFFLHGESNVCTSVEIAQHQPIYLISEEHLHMAQSSPAPFQVLVSPYGLNGTLTGHAYKMSDPATRKLIEEWQYFYPMVLRKKEESREEAELGYDDDFPVAVEVIVGGVRMVYPSAFVLISQNDIPVPQSTASVGGHISVAQQGLGSVKDPSNCGMPLTPPTSPEQVVIGESGGMQSAASHLSSQDGGMITMHSPKRSRKIPPKLHNHMVHRVWKECILNRAQSKRSQVSTPTQEEEPAHNPAAWDFVDPTQRVSCSCSRHKLLKRCTVGPSRPPTVSQPGFSTGPPSSSSLPPPASSKHKTAERQEKGDKLQKRPLVPFHHRPSVAEELCMEQDASGQKLGLAGIDASLEVSSSRKYDKQMAVPSRNTSKQLNLNPMDSPHSPISPLPPTLSPQPRGQEAESLDPPSVPVNSALYGNGLELQQLSTLDDRTVLVGQRLPLMAEVSETALYSGIRPSYTESSDKWWQGFRLPSSEDAEFRPPELQGDRFDIKLDVNPESTALQRLLAQPNKRFKIWQDEQPQVQPLPFLDPSPLSQQPGDALGEVNDPYTFEDGDIKYIFTANKKCKQGTEKDTLKKNKSEDGFGTKDVTTPGHSTPVPDGKNAMSIFSSATKTDVRQDNAAGRAGSGSLTQVTDLAPSLHDLDNIFDNSDDDELGAVSPALRSSKMTAVGTEERPPGKDGRSAGPYPPTVADLQRMFPTPPSLEQHPAFSPVMNYKDGVSSETVTALGMMESPVVSMVPTHFTEFRMEVEDGLGSPKPEEIKDFSYVHKVPQFQPFVGSSMFAPLKTLPSHCLLPLKTPDACLFRPSWAVPPKMEQLPMPPAAASIRDGYNNVPSVGSLADPDYLNTPQMNTPVTLNSTAPASNSGAGVLPSPATPRFSVPTPRTPRTPRTPRGGGTASGQGSVKYDSTDQGSPASTPSTTRPLNSVEPATMQPIPEAHSLYVTLILSDSVMNVFKDRNFDSCCICACNMNIKGADVGLYIPDSSKEDQYRCTCGFSAIMNRKLGYNSGLFLEDELDIFGKNSDIGQAAERRLMMCQSTFLPQMEGARKSPEPPISLLLLLQNQHTQPFASLSFLDYISSNSRHALPCVSWTYDRVQADNNDYWTECFNALEQGRQYVDNPTGGKVDEALVRSATVHCWPHSNVLDTSMLSSQDVVRMLLSLQPFLQDAIQKKRTGRTWENIQHVQGPLTWQQFHKMAGRGTYGSEESPEPLPIPTLLVGYDKEFLTISPFSLPFWERLLLEPYGGHRDVAYIVVCPENEALLEGAKTFFRDLSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQKLTEELVSEWFNQPWSSEENDNHSRLKLYAQVCRHHLAPYLATLQLDSGLLMPPKHQSPPAEAQGQATPGNAGSLPSSAGSVAPPAGSSFNPTSNSSANPAASSSSASSGPPGSSTASASGITQMNTTSSSGFSGGVGGQNPNTGGSSADRAPGNVACGDTEPGQSSAQPSQDGQDSVTERERIGIPTEPDSADSHAYPPAVVIYMVDPFTYTAEEDSSSGNFWLLSLMRCYTEMLDHLPEHMRSSFILQIVPCQYMLQTMKDEHVFYIQYLKSMAFSVYCQCRRPLPTQIHIKSLTGFGPAASIEMTLKNPERPSPIQLYSPPFILAPIKDKQTEPGETFGEASQKYNVLFVGYCLSHDQRWLLASCTDLHGELLETCVVNIALPSRTLPVSVSVRSRKSKVSARKIGLQKLWEWCLGIVQMTSLPWRVVIGRLGRLGHGELKDWSILLGECSLQTISKQLKDVCRMCGISAADSPSILSACLVAMEPQGSFVVMPGQAIITGVLHRVL", 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Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613673.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035299982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299982" } ] }, { "annotation": "Has antibacterial activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZL1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZL1#function" }, { "database": "UniProtKB", "id": "RU231113", "url": "https://www.uniprot.org/uniprotkb/RU231113#function" }, { "database": "UniProtKB", "id": "ARBA00002878", "url": "https://www.uniprot.org/uniprotkb/ARBA00002878#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZL1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZL1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Defb135", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZL1", "locus": {} } ], "crossref": [ { "id": "100757570", "url": "https://www.ncbi.nlm.nih.gov/gene/100757570", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050544", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050544", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757570", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757570", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NTCWRTK", "url": "https://omabrowser.org/oma/group/NTCWRTK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MZL1", "url": "https://www.orthodb.org/?gene=A0A8C2MZL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15001:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15001:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035299982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299982", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZL1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSLQLILVVFVLLSYVPPVRSGLNIYIKRMFDSCWLLKGTCRESCQPREIFNIFCGTQYLCCIDPEDMPTLFVK", "length": 75, "header": "tr|A0A8C2MZL1-1|A0A8C2MZL1_CRIGR Isoform 1 of Beta-defensin OS=Cricetulus griseus OX=10029 GN=Defb135 PE=3 SV=1 CANONICAL=A0A8C2MZL1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZL1/entry#A0A8C2MZL1-1", "sequence": { "sequence": "MRSLQLILVVFVLLSYVPPVRSGLNIYIKRMFDSCWLLKGTCRESCQPREIFNIFCGTQYLCCIDPEDMPTLFVK", "length": 75, "header": "tr|A0A8C2MZL1-1|A0A8C2MZL1_CRIGR Isoform 1 of Beta-defensin OS=Cricetulus griseus OX=10029 GN=Defb135 PE=3 SV=1 CANONICAL=A0A8C2MZL1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZL1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZL1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757570", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757570", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q30KN4-1", "protein_name": "Beta-defensin 30", "gene_name": "Defb30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSLQLTLVLFVLLSYVPPVRSGVNMYIKRIYDTCWKLKGICRNTCQKEEIYHIFCGIQSLCCLEKKEMPVLFVK", "length": 75 }, "evidence": [ { "id": "A0A8C2MZL1", "url": "https://omabrowser.org/oma/group/A0A8C2MZL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q30KP9-1", "protein_name": "Beta-defensin 135", "gene_name": "DEFB135", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATRSVLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCCVNPKYLPILTGK", "length": 77 }, "evidence": [ { "id": "A0A8C2MZL1", "url": "https://omabrowser.org/oma/group/A0A8C2MZL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q32ZG2-1", "protein_name": "Beta-defensin 30", "gene_name": "Defb30", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSLQLILVLFVLLSDVPPVRSGVNMYIRQIYDTCWKLKGHCRNVCGKKEIFHIFCGTQFLCCIERKEMPVLFVK", "length": 75 }, "evidence": [ { "id": "A0A8C2MZL1", "url": "https://omabrowser.org/oma/group/A0A8C2MZL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZL1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZL1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZL1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZL1" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZL1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZL1" }, { "id": "PF13841", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13841" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-defensin", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 63, "start_aa": "Ser", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"XP_027257754", "name": "ralBP1-associated Eps domain-containing protein 1 isoform X8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257754" }, "gene_names": [ { "name": "Reps1", "type": "recommended", "evidence": [ { "id": "A0A8C2MZM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2" } ] }, { "name": "Reps1", "type": "synonym", "evidence": [ { "id": "XP_027257754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257754" } ] } ], "protein_names": [ { "name": "RalBP1-associated Eps domain-containing protein 1 isoform X8", "type": "synonym", "evidence": [ { "id": "A0A8C2MZM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2/entry#names_and_taxonomy" } ] }, { "name": "ralBP1-associated Eps domain-containing protein 1 isoform X8", "type": "synonym", "evidence": [ { "id": "XP_027257754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257754" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027257754", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257754" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Reps1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2", "locus": {} } ], "crossref": [ { "id": "cd00052", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00052", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770024", "url": "https://www.ncbi.nlm.nih.gov/gene/100770024", "database": "GeneID", "categories": [ "Genome 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11216", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11216:SF63", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11216:SF63", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027257754", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257754", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0B6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0B6", "database": "UniProtKB", "categories": [ 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"MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHATSYSSDSENQGSYSGVIPPPPGRGQVKKGPGSHDAVQPRPAADQQEPASPVVSPQQSPPTSPHTWRKHNRHPSGGNSERPLAGPGPFWSPFGDTQSGSSAGDAVWSGQSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTANEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTSSDHTNPTSPLLVKTSDLSEENKINSSVKFPSGNTVADGYSSSDSFPSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFAVTTGQQQTGAVAHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVTEEQDGEAEKHPEVLPTEKASDPATSLRIAQADGKIEEKTAASVPANVSKGTTPLAPPPKPVRRRLKSEDELRPDVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL", "length": 796, "header": "tr|A0A8C2MZM2-1|A0A8C2MZM2_CRIGR Isoform 1 of RalBP1-associated Eps domain-containing protein 1 isoform X8 OS=Cricetulus griseus OX=10029 GN=Reps1 PE=4 SV=1 CANONICAL=A0A8C2MZM2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2/entry#A0A8C2MZM2-1", "sequence": { "sequence": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHATSYSSDSENQGSYSGVIPPPPGRGQVKKGPGSHDAVQPRPAADQQEPASPVVSPQQSPPTSPHTWRKHNRHPSGGNSERPLAGPGPFWSPFGDTQSGSSAGDAVWSGQSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTANEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTSSDHTNPTSPLLVKTSDLSEENKINSSVKFPSGNTVADGYSSSDSFPSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFAVTTGQQQTGAVAHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVTEEQDGEAEKHPEVLPTEKASDPATSLRIAQADGKIEEKTAASVPANVSKGTTPLAPPPKPVRRRLKSEDELRPDVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL", "length": 796, "header": "tr|A0A8C2MZM2-1|A0A8C2MZM2_CRIGR Isoform 1 of RalBP1-associated Eps domain-containing protein 1 isoform X8 OS=Cricetulus griseus OX=10029 GN=Reps1 PE=4 SV=1 CANONICAL=A0A8C2MZM2-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N0B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2/entry#A0A8C2N0B6-1", "sequence": { "sequence": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHATSYSSDSENQGSYSGVIPPPPGRGQVKKGPGSHDAVQPRPAADQQEPASPVVSPQQSPPTSPHTWRKHNRHPSGGNSERPLAGPGPFWSPFGDTQSGSSAGDAVWSGQSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTANEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEDTAIVHPVPIRMTPSKIHMQEMELKRTSSDHTNPTSPLLVKTSDLSEENKINSSVKFPSGNTVDGYSSSDSFPSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFAVTTGQQQTGAVAHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVTEEQDGEAEKHPEVLPTEKASDPATSLRIAQADGKIEEKTAASVPANVSKGTTPLAPPPKPVRRRLKSEDELRPDVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL", "length": 768, "header": "tr|A0A8C2N0B6-1|A0A8C2N0B6_CRIGR Computationally mapped isoform of RalBP1-associated Eps domain-containing protein 1 isoform X14 OS=Cricetulus griseus OX=10029 GN=Reps1 PE=4 SV=1 CANONICAL=A0A8C2MZM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FED0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2/entry#A0A9J7FED0-1", "sequence": { "sequence": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHATSYSSDSENQGSYSGVIPPPPGRGQVKKGPGSHDAVQPRPAADQQEPASPVVSPQQSPPTSPHTWRKHNRHPSGGNSERPLAGPGPFWSPFGDTQSGSSAGDAVWSGQSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTANEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEDTAIVHPVPIRMTPSKIHMQEMELKRTSSDHTNPTSPLLVKTSDLSEENKINSSVKFPSGNTVADGYSSSDSFPSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFAVTTGQQQTGAVAHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVTEEQDGEAEKHPEVLPTEKASDPATSLRIAQADGKIEEKTAASVPANVSKGTTPLAPPPKPVRRRLKSEDELRPDVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL", "length": 769, "header": "tr|A0A9J7FED0-1|A0A8C2MZM2_CRIGR Computationally mapped isoform of RalBP1-associated Eps domain-containing protein 1 isoform X8 OS=Cricetulus griseus OX=10029 GN=Reps1 PE=4 SV=1 CANONICAL=A0A8C2MZM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FFM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2/entry#A0A9J7FFM5-1", "sequence": { "sequence": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHATSYSSDSENQGSYSGVIPPPPGRGQVKKGPGSHDAVQPRPAADQQEPASPVVSPQQSPPTSPHTWRKHNRHPSGGNSERPLAGPGPFWSPFGDTQSGSSAGDAVWSGQSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTANEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTSSDHTNPTSPLLVKTSDLSEENKINSSVKFPSGNTVDGYSSSDSFPSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFAVTTGQQQTGAVAHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVTEEQDGEAEKHPEVLPTEKASDPATSLRIAQADGKIEEKTAASVPANVSKGTTPLAPPPKPVRRRLKSEDELRPDVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL", "length": 795, "header": "tr|A0A9J7FFM5-1|A0A8C2MZM2_CRIGR Computationally mapped isoform of RalBP1-associated Eps domain-containing protein 1 isoform X8 OS=Cricetulus griseus OX=10029 GN=Reps1 PE=4 SV=1 CANONICAL=A0A8C2MZM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JA21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2/entry#A0A9J7JA21-1", "sequence": { "sequence": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHATSYSSDSENQGSYSGVIPPPPGRGQVKKGPGSHDAVQPRPAADQQEPASPVVSPQQSPPTSPHTWRKHNRHPSGGNSERPLAGPGPFWSPFGDTQSGSSAGDAVWSGQSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTANEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTSSDHTNPTSPLLVKTSDLSEENKINSSVKFPSGNTVADGYSSSDSFPSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFAVTTGQQQTGAVAHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVTEEQDGEAEKHPEVLPTEKASDPATSLRIAQADGKIEEKTAASVPANVSKGTTPLAPPPKPVRRRLKSEDELRPDVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL", "length": 795, "header": "tr|A0A9J7JA21-1|A0A9J7JA21_CRIGR Computationally mapped isoform of RalBP1-associated Eps domain-containing protein 1 isoform X10 OS=Cricetulus griseus OX=10029 GN=Reps1 PE=4 SV=1 CANONICAL=A0A8C2MZM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JFM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2/entry#A0A9J7JFM7-1", "sequence": { "sequence": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHATSYSSDSENQGSYSGVIPPPPGRGQVKKGPGSHDAVQPRPAADQQEPASPVVSPQQSPPTSPHTWRKHNRHPSGGNSERPLAGPGPFWSPFGDTQSGSSAGDAVWSGQSPPPPQENWDQTTVRTVASATTANEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTSSDHTNPTSPLLVKTSDLSEENKINSSVKFPSGNTVADGYSSSDSFPSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFAVTTGQQQTGAVAHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVTEEQDGEAEKHPEVLPTEKASDPATSLRIAQADGKIEEKTAASVPANVSKGTTPLAPPPKPVRRRLKSEDELRPDVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL", "length": 775, "header": "tr|A0A9J7JFM7-1|A0A9J7JFM7_CRIGR Computationally mapped isoform of RalBP1-associated Eps domain-containing protein 1 isoform X12 OS=Cricetulus griseus OX=10029 GN=Reps1 PE=4 SV=1 CANONICAL=A0A8C2MZM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JFX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2/entry#A0A9J7JFX8-1", "sequence": { "sequence": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHATSYSSDSENQGSYSGVIPPPPGRGQVKKGPGSHDAVQPRPAADQQEPASPVVSPQQSPPTSPHTWRKHNRHPSGGNSERPLAGPGPFWSPFGDTQSGSSAGDAVWSGQSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTANEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTSSDHTNPTSPLLVKTSDLSEENKINSSVKFPSGNTVADGYSSSDSFPSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFAVTTGQQQTGAVAHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVTEEQDGEAEKHPEVLPTEKASDPATSLRIAQADGKIEEKTAASVPANVSKGTTPLAPPPKPVRRRLKSEDELRPDVDEHTQKTGVLAAVLASQPSIPRMFLRREFPWKFNWNNSDHSLTSKPIAVNCEHAHFEAVLGLEPIWKPKHSAHCFIEH", "length": 795, "header": "tr|A0A9J7JFX8-1|A0A9J7JFX8_CRIGR Computationally mapped isoform of RalBP1-associated Eps domain-containing protein 1 isoform X11 OS=Cricetulus griseus OX=10029 GN=Reps1 PE=4 SV=1 CANONICAL=A0A8C2MZM2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 572, "start_aa": "Thr", "end_pos": 572, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr572", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FED0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FED0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FED0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FED0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770024", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770024", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZM2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" }, { "start_pos": 566, "end_pos": 568, "annotation": "n_glycosylation_sequon" }, { "start_pos": 640, "end_pos": 642, "annotation": "n_glycosylation_sequon" }, { "start_pos": 688, "end_pos": 690, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MZM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 318, "end_pos": 353, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MZM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZM2" }, { "id": "PS50031", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50031" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EH", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 113, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 572 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 408, "end_pos": 410 }, { "start_pos": 415, "end_pos": 417 }, { "start_pos": 498, "end_pos": 500 }, { "start_pos": 529, "end_pos": 531 }, { "start_pos": 566, "end_pos": 568 }, { "start_pos": 640, "end_pos": 642 }, { "start_pos": 688, "end_pos": 690 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MZP0-1", "uniprot_ac": "A0A8C2MZP0", "uniprot_id": "A0A8C2MZP0_CRIGR", "mass": { "chemical_mass": 58892.0, "monoisotopic_mass": 58892.0 }, "refseq": { "ac": "XP_003509929", "name": "tubulin-specific chaperone E isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509929" }, "gene_names": [ { "name": "Tbce", "type": "recommended", "evidence": [ { "id": "A0A8C2MZP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0" } ] }, { "name": "Tbce", "type": "synonym", "evidence": [ { "id": "XP_003509929", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509929" } ] } ], "protein_names": [ { "name": "Tubulin-specific chaperone E", "type": "recommended", "evidence": [ { "id": "A0A8C2MZP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0/entry#names_and_taxonomy" } ] }, { "name": "Tubulin-folding cofactor E", "type": "synonym", "evidence": [ { "id": "A0A8C2MZP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0/entry#names_and_taxonomy" } ] }, { "name": "tubulin-specific chaperone E isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003509929", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509929" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614791.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509929", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509929" } ] }, { "annotation": "Tubulin-folding protein; involved in the second step of the tubulin folding pathway and in the regulation of tubulin heterodimer dissociation. Required for correct organization of microtubule cytoskeleton and mitotic splindle, and maintenance of the neuronal microtubule network.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FPM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPM3#function" }, { "database": "UniProtKB", "id": "ARBA00045331", "url": "https://www.uniprot.org/uniprotkb/ARBA00045331#function" }, { "database": "UniProtKB", "id": "A0A9J7JKN2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKN2#function" }, { "database": "UniProtKB", "id": "A0A8C2MZP0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZP0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tbce", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0", "locus": {} } ], "crossref": [ { "id": "cd17044", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17044", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767699", "url": "https://www.ncbi.nlm.nih.gov/gene/100767699", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767699", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767699", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SEESHMF", "url": "https://omabrowser.org/oma/group/SEESHMF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MZP0", "url": "https://www.orthodb.org/?gene=A0A8C2MZP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FPM3", "url": "https://www.orthodb.org/?gene=A0A9J7FPM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JKN2", "url": "https://www.orthodb.org/?gene=A0A9J7JKN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JLB8", "url": "https://www.orthodb.org/?gene=A0A9J7JLB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18849:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18849:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01302", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01302", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509929", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509929", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZP0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FPM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FPM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKN2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLB8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDILPLDVIGRRVDVNGEFATVRFCGTVPPVAGLWLGVEWDNPKRGKHDGSHEGTMYFKCRHPTGGSFVRPNKANFGVDFLTALKKRYALEDGSDDDGKSCSLIVGSKQVQTVGFENITKKQSQLRALQDISLWKCAVNCAGEQGRIAEACPNIRVVNLSKNLLSSWDEVILIAEQLNNLESLDLSENKLQFPSDSPTPTGTFSNLKILVLNKMGITWAEVLRCAPSWPILEELYLKSNNISISERPVNVLQKMRLLDLSSNPAIDESQLCLIAYLPRLEHLLISDIGLSSIHFPDAGIGCKTSMFPSLQYLVVNDNQISEWSFINELDKLQSLQALSCTRNPLCEEDKAEEIIIAKIGQLKTLNRCQILPEERRGAELDYQKTFGNEWKRAGGHPDPDKNRPNAEFLSAHPRYQLLCCKYGAPEDEELKPQQPFMLKNQLLSLKIKCSNQHEQKVLEKQLPDSMTVQKVKGLLSRLLKVPVSELLLSYESPKMPGREIELENDLQSLQFYSVENGDCLLVRW", "length": 524, "header": "tr|A0A8C2MZP0-1|A0A8C2MZP0_CRIGR Isoform 1 of Tubulin-specific chaperone E OS=Cricetulus griseus OX=10029 GN=Tbce PE=3 SV=1 CANONICAL=A0A8C2MZP0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0/entry#A0A8C2MZP0-1", "sequence": { "sequence": "MGDILPLDVIGRRVDVNGEFATVRFCGTVPPVAGLWLGVEWDNPKRGKHDGSHEGTMYFKCRHPTGGSFVRPNKANFGVDFLTALKKRYALEDGSDDDGKSCSLIVGSKQVQTVGFENITKKQSQLRALQDISLWKCAVNCAGEQGRIAEACPNIRVVNLSKNLLSSWDEVILIAEQLNNLESLDLSENKLQFPSDSPTPTGTFSNLKILVLNKMGITWAEVLRCAPSWPILEELYLKSNNISISERPVNVLQKMRLLDLSSNPAIDESQLCLIAYLPRLEHLLISDIGLSSIHFPDAGIGCKTSMFPSLQYLVVNDNQISEWSFINELDKLQSLQALSCTRNPLCEEDKAEEIIIAKIGQLKTLNRCQILPEERRGAELDYQKTFGNEWKRAGGHPDPDKNRPNAEFLSAHPRYQLLCCKYGAPEDEELKPQQPFMLKNQLLSLKIKCSNQHEQKVLEKQLPDSMTVQKVKGLLSRLLKVPVSELLLSYESPKMPGREIELENDLQSLQFYSVENGDCLLVRW", "length": 524, "header": "tr|A0A8C2MZP0-1|A0A8C2MZP0_CRIGR Isoform 1 of Tubulin-specific chaperone E OS=Cricetulus griseus OX=10029 GN=Tbce PE=3 SV=1 CANONICAL=A0A8C2MZP0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FPM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0/entry#A0A9J7FPM3-1", "sequence": { "sequence": "MYFKCRHPTGGSFVRPNKANFGVDFLTALKKRYALEDGSDDDGKSCSLIVGSKQVQTVGFENITKKQSQLRALQDISLWKCAVNCAGEQGRIAEACPNIRVVNLSKNLLSSWDEVILIAEQLNNLESLDLSENKLQFPSDSPTPTGTFSNLKILVLNKMGITWAEVLRCAPSWPILEELYLKSNNISISERPVNVLQKMRLLDLSSNPAIDESQLCLIAYLPRLEHLLISDIGLSSIHFPDAGIGCKTSMFPSLQYLVVNDNQISEWSFINELDKLQSLQALSCTRNPLCEEDKAEEIIIAKIGQLKTLNRCQILPEERRGAELDYQKTFGNEWKRAGGHPDPDKNRPNAEFLSAHPRYQLLCCKYGAPEDEELKPQQPFMLKNQLLSLKIKCSNQHEQKVLEKQLPDSMTVQKVKGLLSRLLKVPVSELLLSYESPKMPGREIELENDLQSLQFYSVENGDCLLVRW", "length": 468, "header": "tr|A0A9J7FPM3-1|A0A8C2MZP0_CRIGR Computationally mapped isoform of Tubulin-specific chaperone E OS=Cricetulus griseus OX=10029 GN=Tbce PE=3 SV=1 CANONICAL=A0A8C2MZP0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0/entry#A0A9J7JKN2-1", "sequence": { "sequence": "MQAVWFPEKPAGNVSRLRSLIYNRHPTGGSFVRPNKANFGVDFLTALKKRYALEDGSDDDGKSCSLIVGSKQVQTVGFENITKKQSQLRALQDISLWKCAVNCAGEQGRIAEACPNIRVVNLSKNLLSSWDEVILIAEQLNNLESLDLSENKLQFPSDSPTPTGTFSNLKILVLNKMGITWAEVLRCAPSWPILEELYLKSNNISISERPVNVLQKMRLLDLSSNPAIDESQLCLIAYLPRLEHLLISDIGLSSIHFPDAGIGCKTSMFPSLQYLVVNDNQISEWSFINELDKLQSLQALSCTRNPLCEEDKAEEIIIAKIGQLKTLNRCQILPEERRGAELDYQKTFGNEWKRAGGHPDPDKNRPNAEFLSAHPRYQLLCCKYGAPEDEELKPQQPFMLKNQLLSLKIKCSNQHEQKVLEKQLPDSMTVQKVKGLLSRLLKVPVSELLLSYESPKMPGREIELENDLQSLQFYSVENGDCLLVRW", "length": 486, "header": "tr|A0A9J7JKN2-1|A0A8C2MZP0_CRIGR Computationally mapped isoform of Tubulin-specific chaperone E OS=Cricetulus griseus OX=10029 GN=Tbce PE=3 SV=1 CANONICAL=A0A8C2MZP0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JLB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0/entry#A0A9J7JLB8-1", "sequence": { "sequence": "MGDILPLDVIGRRVDVNGEFATVRFCGTVPPVAGLWLGVEWDNPKRGKHDGSHEGTMYFKCRHPTGGSFVRPNKANFGVDFLTALKKRYALEDGSDDDGKSCSLIVGSKQVQTVGFENITKKQSQLRALQDISLWKCAVNCAGEQGRIAEACPNIRVVNLSKNLLSSWDEVILIAEQLNNLESLDLSENKLQFPSDSPTPTGTFSNLKILVLNKMGITWAEVLRCAPSWPILEELYLKSNNISISERPVNVLQKMRLLDLSSNPAIDESQLCLIAYLPRLEHLLISDIGLSSIHFPDAGIGCKTSMFPSLQYLVVNDNQISEWSFINELDKLQSLQALSCTRNPLCEEDKAEEIIIAKIGQLKTLNRCQILPEERRGAELDYQKTFGNEWKRAGGHPDPDKNRPNAEFLSAHPRYQLLCCKYGAPEDEELKPQQPFMLKNQLLSLKIKCSNQHEQKVLEKQLPDSMTVQKVKGLLSRLLKVPVSELLLSYESPKVSC", "length": 497, "header": "tr|A0A9J7JLB8-1|A0A8C2MZP0_CRIGR Computationally mapped isoform of Tubulin-specific chaperone E OS=Cricetulus griseus OX=10029 GN=Tbce PE=3 SV=1 CANONICAL=A0A8C2MZP0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FPM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPM3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FPM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPM3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767699", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767699", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A1Z6J5-1", "protein_name": "Tubulin-specific chaperone E", "gene_name": "Tbce", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVGIIDEVQLFYPLGTRIKIGDNYGTVRYVGEVSGHMGSWLGIEWDDGLRGKHNGIVDGKRYFQTQTPTGGSFIRPGKVGPCATLEDAARERYLNYDSSNVDESLIREAQASLQASLFEVVGMDKIARKQSKFEQLEEVSVDQTPVNAAGYLKELTHLTTLNVSHTLIWNWEIVASIAQQLPSLTNLNLSSNRLVLPTSSQITELEPSFRQLKRINLRSCGFSDWKDVMHTALLWPNILSLGLQENSLGQLAEVDRTKIFKQLHELDLHRTNIMDFDQVTKLGNLTTLRLLNIMENGIEEIKLPDCDSQEKLNIFVSLEQLNLLHNPIWNEADAFNELDKLPQLKRLSKTPHLKSNFDEMFSKAVASIASLQFINKAEVTAEQRRGAEYDIWKKYALDWMQATQGGTDSLREFCRRHRTYPLLVKKYGSPADFVPRSQAKQSNLINVSIRHQLTGETWEKKVPRMITVQTLQGLVMKRFRLSGDVPQLCYVDALHPDLVVPLDNNAKTLDFYSVQEHDTVLVQ", "length": 523 }, "evidence": [ { "id": "A0A8C2MZP0", "url": "https://omabrowser.org/oma/group/A0A8C2MZP0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P39937-1", "protein_name": "Protein PAC2", "gene_name": "PAC2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTYEIGDRLKIGGYFCTIKFIGVIKPWPSVKAYGVEWDDHSRGKHSGTIDDIHYFDVQIPNSGSFLKESKIKSPGVRRITFYEALSEKYGGSSNNINDLSIGNKRVEGLGFDELNARNKNYKKLRKIALRDSDVAILFQNQDELNRVIQNCVNVKDLDLSLNLFTNINSLCEFIEPLKNLESLNISQNKLLSGWDNLKEYDLSHIKTLRLSSCGLSYKHIGKLLKSFRTLKMLDLSYNNLTSAGIQNFENEIPCTLEELNISGNNLISFPLFPKNLTLKGLNVSNNQISRAPSIAIYSVESLDITDNKFKERSLIDDLNKTFPSLKNIHLSGNEFNYNGNYINVEEQATFYEVLARFDRVMVLNGSICDVKTRREAEMFFVSKVMNNELSYDTNLPRWSSLIKSYEIDMSKLSFNNERETRQSLVLKIKIRAGKKPSSDLDYWVLPSFTVRYVKSVICRKLNFDILNVKLFHENSEGMINEIKYNFRPISDFNVVNGDIIHVSSPVNNKSIQKVNSPS", "length": 518 }, "evidence": [ { "id": "A0A8C2MZP0", "url": "https://omabrowser.org/oma/group/A0A8C2MZP0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q15813-1", "protein_name": "Tubulin-specific chaperone E", "gene_name": "TBCE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDTLTADVIGRRVEVNGEHATVRFAGVVPPVAGPWLGVEWDNPERGKHDGSHEGTVYFKCRHPTGGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEEDRKEQIVTIGNKPVETIGFDSIMKQQSQLSKLQEVSLRNCAVSCAGEKGGVAEACPNIRKVDLSKNLLSSWDEVIHIADQLRHLEVLNVSENKLKFPSGSVLTGTLSVLKVLVLNQTGITWAEVLRCVAGCPGLEELYLESNNIFISERPTDVLQTVKLLDLSSNQLIDENQLYLIAHLPRLEQLILSDTGISSLHFPDAGIGCKTSMFPSLKYLVVNDNQISQWSFFNELEKLPSLRALSCLRNPLTKEDKEAETARLLIIASIGQLKTLNKCEILPEERRRAELDYRKAFGNEWKQAGGHKDPEKNRLSEEFLTAHPRYQFLCLKYGAPEDWELKTQQPLMLKNQLLTLKIKYPHQLDQKVLEKQLPGSMTIQKVKGLLSRLLKVPVSDLLLSYESPKKPGREIELENDLKSLQFYSVENGDCLLVRW", "length": 527 }, "evidence": [ { "id": "A0A8C2MZP0", "url": "https://omabrowser.org/oma/group/A0A8C2MZP0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q32KS0-1", "protein_name": "Tubulin-specific chaperone E", "gene_name": "TBCE", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNSTSTSDVIGRRVEVNGEHATVRFSGLVPPVAGLWLGVEWDNPERGKHDGSHEGTVYFKCRHPTAGSFIRPHKVNFGVDFLTAIKNRYVLEDEPKEEETEQIVIIGNKPVETIGFDSVIKQQSQLSKLQDVSLRNCAVNGAGDKGEIAKACPNIRSIDLSKNLLSSWEEVIDIADQLKHLEVLNLSENKLTSPSSSPSPTGTFPTLKVLVLNRTGVTWAEVLRCASGWPVLEKLYLESNNIIISERPTDVLQTVKLLDLSSNQLIDENQLFLIAYLPRLEQLILSDIGISSIHFPDAGIGCKTSMFPSLQYLVLNDNQIAQWSFMNELDKLQSLHALSCTRNPLTEGSKDAQTTRQFIIARIGQLRTLNKCAIEPEERRGAELDYRKAFGNEWKKAGGHQDPEKNRPNEEFLAAHPRYQALCLKYGAPEDGELKTQQPFLLKNQLLTLKIKYPNQHDQKVIEKQLPDSMTVQKVKGLLSRLLKVPVSELLLSYESPKMPGKEVELENDLQPLRFYSVENGDCLLVRW", "length": 528 }, "evidence": [ { "id": "A0A8C2MZP0", "url": "https://omabrowser.org/oma/group/A0A8C2MZP0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5FVQ9-1", "protein_name": "Tubulin-specific chaperone E", "gene_name": "Tbce", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDILPLDVIGRRVEVNGEYATVRFCGAVPPVAGLWLGVEWDNPERGKHDGSHEGTMYFKCRHPTGGSFVRPNIVNFGEDFLTALKKRYVLTDGPDDDEKSCSLKVGSKQVQTIGFEHITKKQSQLRSLQDISLWKCAVSCAGERGRIAEACPNIRVVDLSKNLLSTWDEVILIAEQLKDLEALDLSENKLQFPSDSPTLTRTFSTLKTLVLNKTGITWTEVLHCAPSWPVLQELYLKSNGISISERPVNALQNLRLLDLSSNPSIDESQLCLIAYLPRLEHLLLSDIGLSSIHFPDAEIGCKTSMFPALTYLIVNDNQISEWSFINELDKLQSLQALSCARNPLTKGDKAEEIIIAKIGQLKTLNRCQILPEERRGAELDYRKAFGKEWRKAGGHPDPDRNRPSAEFLSAHPRYQLLCCKYGAPEDEELKTQQPFMLKNQLLTLKIKCSNQPEQQILEKQLPDSMTIQKVKGLLSRLLKVPVSELLLSYESSKMPGREIELENDLQPLQFYSVENGDCLLVRW", "length": 524 }, "evidence": [ { "id": "A0A8C2MZP0", "url": "https://omabrowser.org/oma/group/A0A8C2MZP0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5U378-1", "protein_name": "Tubulin-specific chaperone E", "gene_name": "tbce", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMLDEAVGRRVCCDGERGTVRYVGPVPPTAGVWLGVEWDHPERGKHDGSHDGVRYFTCRHPTGGSFVRPQKASFGVDYVTALKQRYEVEIEEVTAEEMKISSKTVVMVGFENVKKKQSVKNLTEVGLRRCEVSAPGPENEIRNTTPFVQSLDLSGNLLSSWEVLAAITEQLDSLQELHLSHNRLSISSAPSSLSSAFSHLRVLSINSCALTWTQVLHCAPMWQQVEELYLADNNITELLRPEHVLQALTVLDLSNNQIAQETVLEISHLPRLERLNLSSTSLSEIKFSDVPAGKKTTLFPALKELLLDDNNISEWRVVNELEKLPSLVYLSCRRNPLLHKEKNLETARQIMIARLGQLELLDMRQILSDERRGAELDYCKMFGSAWLRAGGHREAEKNNPNTDFMTEHPRYLTLIQKYGAPDEGELREQKPFALKNQLLTITFLCPEDLERKPIEKKLPGSMIVQKVKGLLHRLLKLPGVELKLTYTCAKMADREIEIDNDLKPLQFYSVEDGDKILVRWS", "length": 521 }, "evidence": [ { "id": "A0A8C2MZP0", "url": "https://omabrowser.org/oma/group/A0A8C2MZP0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8CIV8-1", "protein_name": "Tubulin-specific chaperone E", "gene_name": "Tbce", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDILPLDVIGRRVEVNGEYATVRFCGAVPPVAGLWLGVEWDNPERGKHDGSHEGTMYFKCRHPTGGSFVRPSKVNFGDDFLTALKKRYVLEDGPDDDENSCSLKVGSKQVQTIGFEHITKKQSQLRALQDISLWNCAVSHAGEQGRIAEACPNIRVVNLSKNLLSTWDEVVLIAEQLKDLEALDLSENKLQFPSDSPTLTRTFSTLKTLVLNKTGITWTEVLHCAPSWPVLEELYLKSNNISISERPVNVLQKMRLLDLSSNPSIDESQLSLIADLPRLEHLVLSDIGLSSIHFPDAEIGCKTSMFPALKYLIVNDNQISEWSFINELDKLQSLQALSCTRNPLSKADKAEEIIIAKIAQLRTLNRCQILPEERRGAELDYRKAFGNEWRKAGGHPDPDKNRPNAAFLSAHPRYQLLCCKYGAPEDEELKTQQPFMLKKQLLTLKIKCSNQPERQILEKQLPDSMTVQKVKGLLSRLLKVPVSELLLSYESSKMPGREIELENDLQPLQFYSVENGDCLLVRW", "length": 524 }, "evidence": [ { "id": "A0A8C2MZP0", "url": "https://omabrowser.org/oma/group/A0A8C2MZP0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8GRL7-1", "protein_name": "Tubulin-folding cofactor E", "gene_name": "TFCE", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKAESSNESFIIGQRVHSLNDSRRVGTVKYVGDVEGYSGTWIGVDWDQDGDGKHNGSVNGVFYFNGRSQSSASFVRSQNLSRGITLLQALELRYRTISTKDEEDEMYVLSAGNRRVSIQLLGGDKIQDKLSRFEELTSASLSYLGVSSLGVSSDLGSILPNLKLLDLTGNLISDWEEIGALCEQLPALTTLNLSCNSLSSDIKSLPQLKNIRVLVLNNSGLSWTQVEILRRSLPGIEELHLMGNMISTITSTSSSDDQAFNSLRLLNLDDNCISDWSEVLKLSQLPCLEQLYLNKNKLSRIFQSVNGTESSEKGSDPFPSLSCLLLGANNIGDLASVDALNGFPQLVDIRLSENPISDPVRGGVPRFVLVARLTKVQVLNGSEVRAREKKDSEIRYVRMVMSKLNDKSGEIELLHPRFYELKKLHGIEDERASAENSGPKNIASGLISITLKCVGPSMGEKPHLTKKLPGSITVGKLKILSENFFKLKSIKPRLFLQEEGSPFPTALDDETATLLDVGICDGSTLLVDEES", "length": 531 }, "evidence": [ { "id": "A0A8C2MZP0", "url": "https://omabrowser.org/oma/group/A0A8C2MZP0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZP0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZP0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZP0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0" } ], "pmid": "" }, { "name": "post-chaperonin tubulin folding pathway", "id": "GO:0007023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007023", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZP0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZP0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MZP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0" }, { "id": "PS50245", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50245" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CAP-Gly", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 71, "start_aa": "Gly", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MZP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP0" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 443, "end_pos": 522, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 241, "end_pos": 243 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MZQ7-1", "uniprot_ac": "A0A8C2MZQ7", "uniprot_id": "A0A8C2MZQ7_CRIGR", "mass": { "chemical_mass": 98574.0, "monoisotopic_mass": 98574.0 }, "refseq": { "ac": "XP_007651273", "name": "piwi-like protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651273" }, "gene_names": [ { "name": "Piwil1", "type": "recommended", "evidence": [ { "id": "A0A8C2MZQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7" } ] }, { "name": "Piwil1", "type": "synonym", "evidence": [ { "id": "XP_007651273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651273" } ] } ], "protein_names": [ { "name": "Piwi-like protein 1", "type": "recommended", "evidence": [ { "id": "A0A8C2MZQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7/entry#names_and_taxonomy" } ] }, { "name": "piwi-like protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007651273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651273" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615530.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007651273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651273" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Piwil1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7", "locus": {} } ], "crossref": [ { "id": "cd02845", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02845", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04658", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04658", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758611", "url": "https://www.ncbi.nlm.nih.gov/gene/100758611", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758611", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758611", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RRDFHDT", "url": "https://omabrowser.org/oma/group/RRDFHDT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MZQ7", "url": "https://www.orthodb.org/?gene=A0A8C2MZQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22891", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22891", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05831", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05831", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23278", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23278", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007651273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651273", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGRARARARGRARGQETVQHVGAAASQQPGYIPPRPQQSPAEGDLVGRGRQRGMVVGATSKSQELQISAGFQELSLAERGGRRRDFHDLGVNTRQNLDHVKESKTGSSGIIVKLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGRCHAFDGTILFLPKRLQHKVTEVFSQTRNGEHVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPSDPIDIPNHRLVIWPGFTTSILQYENNIMLCTDVSHKVLRSETVLDFMFNLYQQTEEHKFQEQVSKELIGLIVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKDDNVQRELRDWGLSFDSNLLSFSGRILQSEKIHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAANSLIQNLFKVTPAMGIQMKKAIMIEVDDRTEAYLRALQQKVTSDTQIVVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDMPLKLAMIVGIDCYHDTTAGRRSIAGFVASINEGMTRWFSRCVFQDRGQELVDGLKVCLQAALRAWSSCNEYMPSRVIVYRDGVGDGQLKTLVNYEVPQFLDCLKSVGRGYNPRLTVIVVKKRVNARFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDSSGLKPDHIQRLTYKLCHVYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL", "length": 862, "header": "tr|A0A8C2MZQ7-1|A0A8C2MZQ7_CRIGR Isoform 1 of Piwi-like protein 1 OS=Cricetulus griseus OX=10029 GN=Piwil1 PE=3 SV=1 CANONICAL=A0A8C2MZQ7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7/entry#A0A8C2MZQ7-1", "sequence": { "sequence": "MTGRARARARGRARGQETVQHVGAAASQQPGYIPPRPQQSPAEGDLVGRGRQRGMVVGATSKSQELQISAGFQELSLAERGGRRRDFHDLGVNTRQNLDHVKESKTGSSGIIVKLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGRCHAFDGTILFLPKRLQHKVTEVFSQTRNGEHVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPSDPIDIPNHRLVIWPGFTTSILQYENNIMLCTDVSHKVLRSETVLDFMFNLYQQTEEHKFQEQVSKELIGLIVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKDDNVQRELRDWGLSFDSNLLSFSGRILQSEKIHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAANSLIQNLFKVTPAMGIQMKKAIMIEVDDRTEAYLRALQQKVTSDTQIVVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDMPLKLAMIVGIDCYHDTTAGRRSIAGFVASINEGMTRWFSRCVFQDRGQELVDGLKVCLQAALRAWSSCNEYMPSRVIVYRDGVGDGQLKTLVNYEVPQFLDCLKSVGRGYNPRLTVIVVKKRVNARFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDSSGLKPDHIQRLTYKLCHVYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL", "length": 862, "header": "tr|A0A8C2MZQ7-1|A0A8C2MZQ7_CRIGR Isoform 1 of Piwi-like protein 1 OS=Cricetulus griseus OX=10029 GN=Piwil1 PE=3 SV=1 CANONICAL=A0A8C2MZQ7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 582, "start_aa": "Thr", "end_pos": 582, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr582", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758611", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758611", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6N7Y9-1", "protein_name": "Piwi-like protein 1", "gene_name": "PIWIL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTGRARARARGRPPGQEAAIPPVGAASAQKTLPSHPSEQRQSLQPCHPPPLTEEPGGRGRQRGPQDAPKTLGLQISAGFQELSLADRGGRRRDFHDLGVNTRQAIEHVRESKTGSSGAMIKLIANFFRLTSRPQWALYQYHVDYNPEMEARRLRSGLLFQHEDLIGKTHAFDGSILFLPKRLPNKVTEVYSKTRNGEDVRITITLTNELPPTSPTCLQFYNIIFRRLLKMMNFQQIGRNYYNPKDPVSIPNHRLMVWPGFTSSILQYEESIMLCADVSHKILRSETVLDFMYSLYEQVEERRFRDACAKELIGVIVLTKYNNRTYRVDDIDWDANPQCTFRRADGSEISYIDYYKRQYNQDISDLNQPVLISQYRRKRGNVTVGPVVLIPELCYLTGLTEKMRNDFNMMKDLAVHTRLSPEQRQREIGKLVDCMKKDECVQKELRDWGLSFDSSLLSFTGRVVQAEKILQAGNVFDYNPQFADWSRETRVAPLIHAKPLDNWLLIYTRRNYDAANMLLQNLFKVTPSMGIRMNKATMIEVDDRTEAYLRVLQQSITPDTNIVVCILSSTRKDKYDAIKKYLCTDCPIPSQCVVARTLSKPQTALAIVTKIALQMNCKMGGELWSVEIPLKQLMIVGIDCYHDTLSGKQSIAGFVASLNEKMTRWFSRCVVQSRGQEIVDGLKACLQTALREWFKWNKYLPSRIIVYRDGVGDGQLNTLVNYEVPQFLDCLKTVGKDYNPRLTVIVVKKRVSTRFFAQAGGGLKNPPPGTVVDIEVTRPEWYDFFIVSQAVRNGCVAPTHYNVVYDTSKLKPDHVQRLTYKLCHMYYNWSGVIRVPAPCQYAHKLAFLVGQSIHREPNLLLSDRLYYL", "length": 867 }, "evidence": [ { "id": "A0A8C2MZQ7", "url": "https://omabrowser.org/oma/group/A0A8C2MZQ7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZTP9-1", "protein_name": "Piwi-like protein 1", "gene_name": "Piwil1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGRARARARGRARGQETVQHVGAAAQSQQPGYIPPRPQQSPTEGDLVGRGRQRGMVVGATSKSQELQISAGFQELSLAERGGRRRDFHDLGVNTRQNLDHVKESKTGSSGIIVKLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGRCHAFDGTILFLPKRLQHKVTEVFSQTRNGEHVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPSDPIDIPNHRLVIWPGFTTSILQYENNIMLCTDVSHKVLRSETVLDFMFNLYQQTEEHKFQEQVSKELIGLIVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKDDNVQRELRDWGLSFDSNLLSFSGRILQSEKIHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAANSLIQNLFKVTPAMGIQMKKAIMIEVDDRTEAYLRALQQKVTSDTQIVVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDMPLKLAMIVGIDCYHDTTAGRRSIAGFVASINEGMTRWFSRCVFQDRGQELVDGLKVCLQAALRAWSGCNEYMPSRVIVYRDGVGDGQLKTLVNYEVPQFLDCLKSVGRGYNPRLTVIVVKKRVNARFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDSSGLKPDHIQRLTYKLCHVYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL", "length": 863 }, "evidence": [ { "id": "A0A8C2MZQ7", "url": "https://omabrowser.org/oma/group/A0A8C2MZQ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BJC4-1", "protein_name": "Piwi-like protein 1", "gene_name": "PIWIL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGRARARARGRARGQEMVQHVGASASQQPGYIQPRPQQPPAEGELVGRGRQRGTVGATAKSQELQISAGFQELSLAERGGRRRDFHDLGVNTRQNLDHVKESKTGSSGIIVRLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGRCHAFDGTILFLPKRLQHKVTEVFSQTRNGEHVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPSDPIDIPNHRLVIWPGFTTSILQYENNIMLCTDVSHKVLRSETVLDFMFNLFHQTEEHKFQEQVSKELIGLIVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKDDNVQRELRDWGLSFDSNLLSFSGRILQAEKIHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAANSLIQNLFKVTPAMGIQMKKAIMIEVDDRTEAYLRVLQQKVTSDTQIVVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDMPLKLAMIVGIDCYHDTTAGRRSIAGFVASINEGMTRWFSRCVFQDRGQELVDGLKVCLQAALRAWNSCNEYMPSRIIVYRDGVGDGQLKTLVNYEVPQFLDCLKSVGRGYNPRLTVIVVKKRVNARFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDSSGLKPDHIQRLTYKLCHVYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL", "length": 861 }, "evidence": [ { "id": "A0A8C2MZQ7", "url": "https://omabrowser.org/oma/group/A0A8C2MZQ7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RFQ4-1", "protein_name": "Piwi-like protein 1", "gene_name": "PIWIL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGRARARARGRARGQETAQHVGAAASQQPGYMQPRPQQPPAEGELVGRGRQRGTVGATAKSQELQISAGFQELSLAERGGRRRDFHDLGVNTRQNLDHVKESKTGSSGIIVRLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGRCHAFDGTILFLPKRLQHKVTEVFSQTRNGEHVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPSDPIDIPNHRLVIWPGFTTSILQYENNIMLCTDVSHKVLRSETVLDFMFNLYNQTEEHKFQEQVSKELIGLIVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKDDNVQRELRDWGLSFDSNLLSFSGRILQAEKIHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAANSLIQNLFKVTPAMGIQMKKAIMIEVDDRTEAYLRVLQQKVTSDTQIVVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDMPLKLAMIVGIDCYHDTTAGRRSIAGFVASINEGMTRWFSRCVFQDRGQELVDGLKVCLQAALRAWNSCNEYMPSRIIVYRDGVGDGQLKTLVNYEVPQFLDCLKSVGRGYNPRLTVIVVKKRVNARFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDSSGLKPDHIQRLTYKLCHVYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL", "length": 861 }, "evidence": [ { "id": "A0A8C2MZQ7", "url": "https://omabrowser.org/oma/group/A0A8C2MZQ7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q54G64-1", "protein_name": "Argonaut-like protein", "gene_name": "agnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIPKKQKGFNGEPKSHQEIDRSQSPLKQRTNNNNYQQQPPQQQQKQQPQQPQQKKQQQKQQQKQQPQQPQQPQQPQQQKQQLQQPQQPQQYFQPRQTQNAWGKQNNSIPLEEQFQEVKPITQPQTPETTTTTTTTTTTTTNTTNTNLLVPRISRRDMVKDSDIENVAIVTAKSRTVQGKQISLISNFFPIVISDRKSLEFRIDFNPPQVTFDKRRKLIRELLSLNNISKEFYFYDGDSILYSPINININSQSIDGVQIFIRKVKEVNHRDKSSVNSQFFNIITKNNMRKMGFSLIGRNYYSPINKIKFEDYLLEVWKGFSTSVVSTESGTMLLADTSSKVVRSETVLDRIKYLRYDKDRCFDEIINSIVLTRYNNKTYRISNISWSSGVNDKMDGTTTFLQYYQRNYPNHKITDYRQPLLKSEVKFRGIKQTIFLIPELTFLTGLSDHMRKNFKLMAELAKHSNFDPSQRYQTLSNFISDINNNPKVSKSLEPWGITYQPALKVDGYVLSAPKNLPNDNKRQLNNIKWAFVVDRDEYERTRDCQTNLYNFINETGMSQPTTICYTDPRDKRPIQYSNIMENAIKTHGIQFFLMLIPQNQPEIYKEIKRKSLVQFKVLTQCIFPRTFYKGRSVTNKLKQQVIAKLGYAPWGLNQQIFNGVIPKKTMIIGIDVGHNSDMRGHSVVGFVATIDDKFQKYFSRSFVQKRPGKEIIDSLEEATKEAMSKYFSFNNCLPELVIVYRDGVGDGMLDLVNRSEIAAMKKGFAETPSSWGIKPKLMYVIVKKNTNARLFTADPIGNPPAGTLVDSKITHPNWYDFFLVSQVTNNGSVNPTHYHVLLDEQKMPADLFQLFTFQMCHLYFNFEKSVRVPATCQFAHKMAFLIGRTVFADAAPQLSDKLFFL", "length": 900 }, "evidence": [ { "id": "A0A8C2MZQ7", "url": "https://omabrowser.org/oma/group/A0A8C2MZQ7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8UVX0-1", "protein_name": "Piwi-like protein 1", "gene_name": "piwil1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGRARARSRGRGRGQEPAAPGAQPPVSQEAAKPVVSTPSEGQLVGRGRQKPAPGAMSEEAMLQISAGFQQVKIGERGGRRRDFHDSGVHTRQLMEHVKESKTGVSGTAIELRANFMRLLSRPMWALYQYHVDYKPPMESRRLRSALLFQHEETLGKAHTFDGAILFLPNKLRNAETVLCSETRNGEKVEITVTLTNELPPSSPVCLQFYNILFRRILRILNMQQIGRHYYNPDDPFNIPQHRLTIWPGFMTTILQYESSIMLCSDVSHKVLRSETVLDFMYSLRQQCGDQRFPEACTKELVGLIILTKYNNKTYRIDDIAWDHTPNNTFKKGDTEISFKNYFKSQYGLDITDGNQVLLVSHVKRLGPSGRPPPGPAMLVPEFCYLTGLTDKMRADFNIMKDLASHTRLSPEQREGRINRLISNINRNGDVQNELTTWGLSFENKLLSLNGRVLPSERIIQGGRAFEYNPWTADWSKEMRGLPLISCMSLDNWLMFYTRRNADVAQSLLQTLNKVSGPMGIRMQRAVMIEYEDRQESLLRALQQNVARETQMVVVILPTNRKDKYDCVKKYLCVDCPTPSQCVVSRTISKPQALMTVATKIALQMNCKMGGELWSVEIPLRQLMIVGIDCYHDTAAGKRSIGAMVASLNQGMSRWFSKCVLQNRGQEIIDALKGSLQGALKAYLKYNNSLPSRIIVYRDGVGDGMLQSVVDYEVPQIMQSIKTMGQDYEPKLSVVVVKKRISSRFFARIDGKIANPPPGTVIDTEVTRPEWYDFFIVSQAVRFGCVAPTHYNVVFDNSGLKPDHMQRLTYKLCHMYYNWQGIVRVPAPCQYAHKLAFLVGQSIHKEPNMNLDDFLYYL", "length": 858 }, "evidence": [ { "id": "A0A8C2MZQ7", "url": "https://omabrowser.org/oma/group/A0A8C2MZQ7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q96J94-1", "protein_name": "Piwi-like protein 1", "gene_name": "PIWIL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGRARARARGRARGQETAQLVGSTASQQPGYIQPRPQPPPAEGELFGRGRQRGTAGGTAKSQGLQISAGFQELSLAERGGRRRDFHDLGVNTRQNLDHVKESKTGSSGIIVRLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGKCHAFDGTILFLPKRLQQKVTEVFSKTRNGEDVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPNDPIDIPSHRLVIWPGFTTSILQYENSIMLCTDVSHKVLRSETVLDFMFNFYHQTEEHKFQEQVSKELIGLVVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKNDNVQRELRDWGLSFDSNLLSFSGRILQTEKIHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAANSLIQNLFKVTPAMGMQMRKAIMIEVDDRTEAYLRVLQQKVTADTQIVVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDIPLKLVMIVGIDCYHDMTAGRRSIAGFVASINEGMTRWFSRCIFQDRGQELVDGLKVCLQAALRAWNSCNEYMPSRIIVYRDGVGDGQLKTLVNYEVPQFLDCLKSIGRGYNPRLTVIVVKKRVNTRFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDNSGLKPDHIQRLTYKLCHIYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL", "length": 861 }, "evidence": [ { "id": "A0A8C2MZQ7", "url": "https://omabrowser.org/oma/group/A0A8C2MZQ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JMB7-1", "protein_name": "Piwi-like protein 1", "gene_name": "Piwil1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGRARARARGRARGQETVQHVGAAASQQPGYIPPRPQQSPTEGDLVGRGRQRGMVVGATSKSQELQISAGFQELSLAERGGRRRDFHDLGVNTRQNLDHVKESKTGSSGIIVKLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGRCHAFDGTILFLPKRLQHKVTEVFSQTRNGEHVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPSDPIDIPNHRLVIWPGFTTSILQYENNIMLCTDVSHKVLRSETVLDFMFNLYQQTEEHKFQEQVSKELIGLIVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKDDNVQRELRDWGLSFDSNLLSFSGRILQSEKIHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAANSLIQNLFKVTPAMGIQMKKAIMIEVDDRTEAYLRALQQKVTSDTQIVVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDMPLKLAMIVGIDCYHDTTAGRRSIAGFVASINEGMTRWFSRCVFQDRGQELVDGLKVCLQAALRAWSGCNEYMPSRVIVYRDGVGDGQLKTLVNYEVPQFLDCLKSVGRGYNPRLTVIVVKKRVNARFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDSSGLKPDHIQRLTYKLCHVYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL", "length": 862 }, "evidence": [ { "id": "A0A8C2MZQ7", "url": "https://omabrowser.org/oma/group/A0A8C2MZQ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7" } ], "pmid": "" }, { "name": "piRNA binding", "id": "GO:0034584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034584", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 852, "end_pos": 854, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MZQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7" }, { "id": "PS50821", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50821" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PAZ", "eco_id": "ECO_0000259", "start_pos": 279, "end_pos": 392, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MZQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZQ7" }, { "id": "PS50822", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50822" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Piwi", "eco_id": "ECO_0000259", "start_pos": 556, "end_pos": 848, "start_aa": "Ile", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 582 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 315, "end_pos": 317 }, { "start_pos": 852, "end_pos": 854 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MZR9-1", "uniprot_ac": "A0A8C2MZR9", "uniprot_id": "A0A8C2MZR9_CRIGR", "mass": { "chemical_mass": 53474.0, "monoisotopic_mass": 53474.0 }, "refseq": { "ac": "XP_035309805", "name": "galactose-3-O-sulfotransferase 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309805" }, "gene_names": [ { "name": "Gal3st4", "type": "recommended", "evidence": [ { "id": "A0A8C2MZR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZR9" } ] }, { "name": "Gal3st4", "type": "synonym", "evidence": [ { "id": "XP_035309805", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309805" } ] } ], "protein_names": [ { "name": "Galactose-3-O-sulfotransferase 4", "type": "recommended", "evidence": [ { "id": "A0A8C2MZR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZR9/entry#names_and_taxonomy" } ] }, { "name": "Beta-galactose-3-O-sulfotransferase 4", "type": "synonym", "evidence": [ { "id": "A0A8C2MZR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZR9/entry#names_and_taxonomy" } ] }, { "name": "Gal-beta-1,3-GalNAc 3'-sulfotransferase", "type": "synonym", "evidence": [ { "id": "A0A8C2MZR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZR9/entry#names_and_taxonomy" } ] }, { "name": "galactose-3-O-sulfotransferase 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035309805", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309805" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277414.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309805", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309805" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZR9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZR9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gal3st4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZR9", "locus": {} } ], "crossref": [ { "id": "100771720", "url": "https://www.ncbi.nlm.nih.gov/gene/100771720", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771720", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771720", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RTMRLWG", "url": "https://omabrowser.org/oma/group/RTMRLWG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MZR9", "url": "https://www.orthodb.org/?gene=A0A8C2MZR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14647", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14647", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14647:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14647:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06990", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06990", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309805", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309805", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZR9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QPB5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QPB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPLSPARTMRLWRPRSLGVALGVFMTIGFGLQLLGGPFQRRLPVLQLRQSWIPSLGPTMKSCLPRQRLVFLKTHKSGSSSVLSLLHRYGDQQGLRFALPAHYQFGYPKLFQASKVKGYHPQSSDTKKPFHILCHHMRFNLKEVLQVMPSDSFFFSIVRDPAALARSAFSYYKSTSSAFRKAPSLAAFLSNPQAFYRPGGRGNHYARNLLWFDFGLPFPPERRVSSHLPRDPNPLQLHIVPSGAGLGTLFQPMSTVANNNAQPASFASSDFGPSSFIQWGLAWLDSVFDLVMVAEYFDESLVLLADALCWGLDDVVGFMHNAQARSEQRLSAANKSVANEEQQLTARARAWNNLDWALYTHFNRSLWARIEQYGHSRLQRAVAEIRARREALAKRCLMGGEALDPKYITDVRLRPFQFGSAKVLGYVLQSGLSQKEQEECERLATPELQYKDKLDAKQFSPTVSLPLKTSRTLPP", "length": 475, "header": "tr|A0A8C2MZR9-1|A0A8C2MZR9_CRIGR Isoform 1 of Galactose-3-O-sulfotransferase 4 OS=Cricetulus griseus OX=10029 GN=Gal3st4 PE=3 SV=1 CANONICAL=A0A8C2MZR9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZR9/entry#A0A8C2MZR9-1", "sequence": { "sequence": "MGPLSPARTMRLWRPRSLGVALGVFMTIGFGLQLLGGPFQRRLPVLQLRQSWIPSLGPTMKSCLPRQRLVFLKTHKSGSSSVLSLLHRYGDQQGLRFALPAHYQFGYPKLFQASKVKGYHPQSSDTKKPFHILCHHMRFNLKEVLQVMPSDSFFFSIVRDPAALARSAFSYYKSTSSAFRKAPSLAAFLSNPQAFYRPGGRGNHYARNLLWFDFGLPFPPERRVSSHLPRDPNPLQLHIVPSGAGLGTLFQPMSTVANNNAQPASFASSDFGPSSFIQWGLAWLDSVFDLVMVAEYFDESLVLLADALCWGLDDVVGFMHNAQARSEQRLSAANKSVANEEQQLTARARAWNNLDWALYTHFNRSLWARIEQYGHSRLQRAVAEIRARREALAKRCLMGGEALDPKYITDVRLRPFQFGSAKVLGYVLQSGLSQKEQEECERLATPELQYKDKLDAKQFSPTVSLPLKTSRTLPP", "length": 475, "header": "tr|A0A8C2MZR9-1|A0A8C2MZR9_CRIGR Isoform 1 of Galactose-3-O-sulfotransferase 4 OS=Cricetulus griseus OX=10029 GN=Gal3st4 PE=3 SV=1 CANONICAL=A0A8C2MZR9-1" }, "locus": {} }, { "isoform_ac": "A0A8C2QPB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZR9/entry#A0A8C2QPB5-1", "sequence": { "sequence": "MAWTMRLWRPRSLGVALGVFMTIGFGLQLLGGPFQRRLPVLQLRQSWIPSLGPTMKSCLPRQRLVFLKTHKSGSSSVLSLLHRYGDQQGLRFALPAHYQFGYPKLFQASKVKGYHPQSSDTKKPFHILCHHMRFNLKEVLQVMPSDSFFFSIVRDPAALARSAFSYYKSTSSAFRKAPSLAAFLSNPQAFYRPGGRGNHYARNLLWFDFGLPFPPERRVSSHLPRDPNPLQLHIVPSGAGLGTLFQPMSTVANNNAQPASFASSDFGPSSFIQWGLAWLDSVFDLVMVAEYFDESLVLLADALCWGLDDVVGFMHNAQARSEQRLSAANKSVANEEQQLTARARAWNNLDWALYTHFNRSLWARIEQYGHSRLQRAVAEIRARREALAKRCLMGGEALDPKYITDVRLRPFQFGSAKVLGYVLQSGLSQKEQEECERLATPELQYKDKLDAKQFSPTVSLPLKTSRTLPP", "length": 470, "header": "tr|A0A8C2QPB5-1|A0A8C2MZR9_CRIGR Computationally mapped isoform of Galactose-3-O-sulfotransferase 4 OS=Cricetulus griseus OX=10029 GN=Gal3st4 PE=3 SV=1 CANONICAL=A0A8C2MZR9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:100771720", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771720", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZHZ0-1", "protein_name": "Galactose-3-O-sulfotransferase 4", "gene_name": "Gal3st4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPLSPARTMRLWRPRSLGVALGVFMTIGFGLQFLGGSFQRRLPGLQFRQSWIPSLGPTVKSCLPRQRLVFLKTHKSGSSSVLNLLHRYGDQQGLRFALPAHYQFGYPKLFQASKVKGYHPQSSDTQKPFHILCHHMRFNLKEVLQVMPSDSFFFSIVRDPAALARSAFSYYKSASSAFRKAPSLAAFLSNPRAFYRPGARGNHYARNLLWFDFGLPFPPETKTMRVSPHLPRDPKSLQLHIVPSGASPGTLFRPITTAADSYKQPASLASSDFGPSSFIQWGLAWLDSVFDLVMVAEYFDESLVLLADALCWSLDDVVGFMHNAQAGSEQSILSTANKTVATGEDQQLTKQARAWNNLDWALYIHFNRSLWARIEQYGRSRLQRAVAELRARREALARRCLMGGEALDPKYITDVRLRPFQFGSAKVLGYVLQNGLNQKDQEECERLATPELQYKDKLDAKQFPPVVSLPLKTSKPLTP", "length": 480 }, "evidence": [ { "id": "A0A8C2MZR9", "url": "https://omabrowser.org/oma/group/A0A8C2MZR9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N039-1", "protein_name": "Galactose-3-O-sulfotransferase 4", "gene_name": "GAL3ST4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGVLSPTRTMRLWGPRSLGVALGVFMTIGFALQLLGGPFQRRLPGLQLRHSWASSLGPAAPSCPPRQHLVFLKTHKSGSSSVLSLLHRYGDRHGLRFALPARYQFGYPRLFQASRVKGYRPQSGGTQPPFHILCHHMRFNLKEVLQVMPSDSFFFSIVRDPAALARSAFSYYKSTSSAFRKAPSLAAFLANPRAFYRPGARGDHYARNLLWFDFGLPFPPELRTKRGNPHVSRDPNPPQLPSGAGPPAHTLDPNALFHPVPTVADGHSQMSSPASLDLGSSSFIQWNLAWLDSVFDLVLVAEYFDESLVLLADALCWGLDDVVGFMHNAQAGGGQDRSTIDDGGLTTEERQLTARARAWNNLDWALYVHFNRSLWARIKQYGQSRLDSAVAELRARREALAKHCLVGGEALDPKYITDRRFRPFQFGSGKVLGYVLRSGLSLQDQEECERLATPELQYKDKLDAKQFPPTVSLPLKTSRRPSP", "length": 483 }, "evidence": [ { "id": "A0A8C2MZR9", "url": "https://omabrowser.org/oma/group/A0A8C2MZR9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RNN6-1", "protein_name": "Galactose-3-O-sulfotransferase 4", "gene_name": "GAL3ST4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHLSSTRTMRLWGPRSLGVALGVFMTIGFALQFWGGPFQRRLPGLQLRQSWAPSPGLALPSCSPRQRLVFLKTHKSGSSSVLSLLHRYGDRHGLRFALPARYQFGYPRLFEASRVKGYRPQGGGTQPPFHILCHHMRFNLKEVLQVMPSDSFFFSIVRDPAALTRSAFSYYKSTSSAFRKAPSLAAFLANPRAFYRPGARGDHYARNLLWFDFGLPFPPEMRTKRGNPRPPRDPKAPQLRVLPSGAGPPAHTLDPNALFHPVPTLADGHSRTSSPASSDLGSSSFIQWSLAWLDSVFDLVLVAEYFDESLVLLADALCWGLDDVVGFMHNAQAGGRQSGSAVSDDGLTAEDRQLTARARAWNNLDWALYVHFNHSLWERIKQYGQSRLDSAVAELRARREALAKHCLVGGEALDPKYITDRRFRPFQFGSGKVLGYVLRSGLSLQDQEECERLATPELQYKDKLDAKQFPPTVSLPLKNSRLSSP", "length": 486 }, "evidence": [ { "id": "A0A8C2MZR9", "url": "https://omabrowser.org/oma/group/A0A8C2MZR9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glycolipid biosynthetic process", "id": "GO:0009247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009247", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZR9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZR9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZR9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZR9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "galactosylceramide sulfotransferase activity", "id": "GO:0001733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001733", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZR9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZR9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8C2MZS4-1", "uniprot_ac": "A0A8C2MZS4", "uniprot_id": "A0A8C2MZS4_CRIGR", "mass": { "chemical_mass": 41115.0, "monoisotopic_mass": 41115.0 }, "refseq": { "ac": "XP_027284433", "name": "motor neuron and pancreas homeobox protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284433" }, "gene_names": [ { "name": "Mnx1", "type": "recommended", "evidence": [ { "id": "A0A8C2MZS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4" } ] }, { "name": "Mnx1", "type": "synonym", "evidence": [ { "id": "XP_027284433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284433" } ] } ], "protein_names": [ { "name": "Homeobox protein HB9", "type": "recommended", "evidence": [ { "id": "A0A8C2MZS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4/entry#names_and_taxonomy" } ] }, { "name": "motor neuron and pancreas homeobox protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027284433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284433" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027284433", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284433" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZS4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mnx1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4", "locus": {} } ], "crossref": [ { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751599", "url": "https://www.ncbi.nlm.nih.gov/gene/100751599", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751599", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751599", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MZS4", "url": "https://www.orthodb.org/?gene=A0A8C2MZS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24335", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24335", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24335:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24335:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027284433", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284433", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZS4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKSKNFRIDALLAVDPPRAASTQSAPLALVTSLAATASGPGRGGNGGGGTSSGASRSCSPASSEATAAPGDRLRAESPSPPRLLAAHCALLPKPGFLGAGGGGGAAGGPGTPHHHAHPGAAAAAAAAAAAAAAGGLALGLHPGGAQGGAGLPAQAALYGHPVYGYSAAAAAAALAGQHPALSYSYPQVQGAHPSHPADPIKLGAGTFQLDQWLRASTAGMILPKMPDFSSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQAAQEAEKQKGGGGGSGKGCAEEKAEEELLGPPVSGDKASGRRLRDLRDSDPDEEDEDEDDHFPYSNGAGTHAASSDCSSEDDSPPPRPGGPGHQPLPQ", "length": 403, "header": "tr|A0A8C2MZS4-1|A0A8C2MZS4_CRIGR Isoform 1 of Homeobox protein HB9 OS=Cricetulus griseus OX=10029 GN=Mnx1 PE=4 SV=1 CANONICAL=A0A8C2MZS4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4/entry#A0A8C2MZS4-1", "sequence": { "sequence": "MEKSKNFRIDALLAVDPPRAASTQSAPLALVTSLAATASGPGRGGNGGGGTSSGASRSCSPASSEATAAPGDRLRAESPSPPRLLAAHCALLPKPGFLGAGGGGGAAGGPGTPHHHAHPGAAAAAAAAAAAAAAGGLALGLHPGGAQGGAGLPAQAALYGHPVYGYSAAAAAAALAGQHPALSYSYPQVQGAHPSHPADPIKLGAGTFQLDQWLRASTAGMILPKMPDFSSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQAAQEAEKQKGGGGGSGKGCAEEKAEEELLGPPVSGDKASGRRLRDLRDSDPDEEDEDEDDHFPYSNGAGTHAASSDCSSEDDSPPPRPGGPGHQPLPQ", "length": 403, "header": "tr|A0A8C2MZS4-1|A0A8C2MZS4_CRIGR Isoform 1 of Homeobox protein HB9 OS=Cricetulus griseus OX=10029 GN=Mnx1 PE=4 SV=1 CANONICAL=A0A8C2MZS4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZS4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZS4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751599", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751599", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "spinal cord motor neuron cell fate specification", "id": "GO:0021520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021520", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZS4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZS4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZS4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4" } ], "pmid": "" }, { "name": "endocrine pancreas development", "id": "GO:0031018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031018", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZS4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZS4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZS4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZS4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MZS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZS4" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { 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This record is derived from a genomic sequence (NW_003613762.1) annotated using gene prediction method: Gnomon. 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Annotation" ] }, { "id": "IPR006909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762123", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762123", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SVMKEPN", "url": "https://omabrowser.org/oma/group/SVMKEPN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MZT7", "url": "https://www.orthodb.org/?gene=A0A8C2MZT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12585", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12585", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12585:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12585:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04824", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04824", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003499996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499996", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZT7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFYTHVLMSKRGPLAKIWLAAHWEKKLTKAHVFECNLEITIQKILSPKVKIALRTSGHLLLGVVRIYNRKAKYLLADCSEAFLKMKMTFRPGLVDLPKENFEAAYNTITLPEEFHDFDIYNMNEIDVSEPLAQNQSRPEEITLREEYSNDLLFQAGSFGDEPELLRRHSFFDDNILMNSSGLVVEHSSGSLMEEKSLFLDNGDGFGDEGAAGEMIDNLLQDETTLLEDIYLNKETSLPPELPSSIMVEPGNLDDQYLPEDEKLDETTLLSNEEEGFTLDPIDGLDIAERKKSKKRRLLIDPVKEISSKSMHKQLTSFVDTLMVLDLAPPTQRLMMWKKRGGVDTLLSTATQDLIHEELKKLFAKCFLSSDFKLAKLIQKESVRKEVGTKSILEPSVIEEPNSYRELDQPQAWNGVVDGSMGSFQEDINMNINSEQGIFERISPAAEGLSSMNASLTRENCPVELESSGSKQNTEAEKWNQRLFQTLNELRESNKKGMQSFSLINLCRNSDRKQAAAKFYTFLILKKHQAIELSQSVPYADIIATVGPMFHKM", "length": 552, "header": "tr|A0A8C2MZT7-1|A0A8C2MZT7_CRIGR Isoform 1 of Double-strand-break repair protein rad21-like protein 1 OS=Cricetulus griseus OX=10029 GN=Rad21l1 PE=3 SV=1 CANONICAL=A0A8C2MZT7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZT7/entry#A0A8C2MZT7-1", "sequence": { "sequence": "MFYTHVLMSKRGPLAKIWLAAHWEKKLTKAHVFECNLEITIQKILSPKVKIALRTSGHLLLGVVRIYNRKAKYLLADCSEAFLKMKMTFRPGLVDLPKENFEAAYNTITLPEEFHDFDIYNMNEIDVSEPLAQNQSRPEEITLREEYSNDLLFQAGSFGDEPELLRRHSFFDDNILMNSSGLVVEHSSGSLMEEKSLFLDNGDGFGDEGAAGEMIDNLLQDETTLLEDIYLNKETSLPPELPSSIMVEPGNLDDQYLPEDEKLDETTLLSNEEEGFTLDPIDGLDIAERKKSKKRRLLIDPVKEISSKSMHKQLTSFVDTLMVLDLAPPTQRLMMWKKRGGVDTLLSTATQDLIHEELKKLFAKCFLSSDFKLAKLIQKESVRKEVGTKSILEPSVIEEPNSYRELDQPQAWNGVVDGSMGSFQEDINMNINSEQGIFERISPAAEGLSSMNASLTRENCPVELESSGSKQNTEAEKWNQRLFQTLNELRESNKKGMQSFSLINLCRNSDRKQAAAKFYTFLILKKHQAIELSQSVPYADIIATVGPMFHKM", "length": 552, "header": "tr|A0A8C2MZT7-1|A0A8C2MZT7_CRIGR Isoform 1 of Double-strand-break repair protein rad21-like protein 1 OS=Cricetulus griseus OX=10029 GN=Rad21l1 PE=3 SV=1 CANONICAL=A0A8C2MZT7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZT7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZT7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZT7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZT7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762123", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762123", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9S3B6-1", "protein_name": "RAD21 cohesin complex component like 1", "gene_name": "RAD21L1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFYTHVLMSKRGPLAKIWLAAHWEKKLTKAHVFECNLEITIEKILSPKVKIALRTSGHLLLGVVRIYNRKAKYLLADCSEALLKMKMTFRPGLVDLPKESFEAAYSTITLPEEFHDFDTQTMNAIDVSECSIQNQSKPEEITLREDYGNDLLFHAGSFGEEPEILRRHSLFDDSILLSSSGLLLEHSSGSPTGDKSLFCGSGDGFGDEGAAGEMIDNLLQDDQNILLEEMHLNTEISLLPESPNTVVAPDNPECVCSPENEKMDETTVSKEEEEFILDPIDTSDIAEKRKGKNRKLLIDPVKEISSKIMHRQLTSFTDTLMVLELAPPTQRLMMWKQKGGADILLSTAAQDLTHAELKMLFTKCFVSSGFKLGRKLIQKESVKEEMGSKNILETSMMEEPNFLQELSQPKTWKEVTDGSKCSSHENTNKNINSDQDIVEMVSSAAEESSLMNAILAQEIENCPMELESNKMGMQYFSLMKLCRNSDRKQTAAKFYSFLMLKKHQAIELSQSAPYADIIATVGPMFHKM", "length": 528 }, "evidence": [ { "id": "A0A8C2MZT7", "url": "https://omabrowser.org/oma/group/A0A8C2MZT7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A2AU37-1", "protein_name": "Double-strand-break repair protein rad21-like protein 1", "gene_name": "Rad21l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFYTHVLMSKRGPLAKIWLAAHWEKKLTKAHVFECNLEITIQKIISPKVKIALRTSGHLLLGVVRIYNRKAKYLLADCSEAFLKMKMTFRPGLVDLPKENFEAAYNTITLPEEFHDFEIYNINEIDISEPLAQNQSRPEEITLREEYSNDLLFQAGSFGDEPEILRRHSFFDDNILMNSSGLVVEHSSGSFAEEKSLFFDNGDGFGDEGAAGEMIDNLLQDESTFLEEAYLNKEVSLPPELPSSIMVEPGNSDDQCIPEDEEINEITLLSNEDEGFTLDPIDDLDIADRRRRKKRRLLVDPVKEISSKAMHRQLASFMDTLMVLDLAPPTQRLMMWKKRGGVDMLLSTATQDLINDELKMLFTKCFLSSDYKLAKLTLKESVRKEVGNQQIAEPSVMGEPNSHSELDQPQDWKDVTDESVGSFQENVNMNVNSEQDILGMISPAVEGLSSMNGSLAQENCPAELESSGSKQNTEAEKWNQRLFQTLNVLREFNKMGMQSFSLKKLCRNSDRKQAAAKFYTLLILKKHRAIELSQSVPYADIIATVGPMFYKM", "length": 552 }, "evidence": [ { "id": "A0A8C2MZT7", "url": "https://omabrowser.org/oma/group/A0A8C2MZT7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4ADQ7-1", "protein_name": "RAD21 cohesin complex component like 1", "gene_name": "Rad21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFYTHVLMSKRGPLAKIWLAAHWEKKLTKAHVFECNLEITIQKIISPKVKIALRTSGHLLLGVVRIYNRKAKYLLADCSEAFLKMKMTFRPGLVDLPKENFEAAYNTITLPEEFHDFDIYNTNDIDISEPLAQNQSRPEEITLREEYSTDLLFQTGSFGDEPELLRRHSFFDDNILMNSSGLVVEHSSGSLTEEKSLFFDNGDGFGDEGAAGEMIDHLLQDENTFFEDTYLNKEVFLPPEVPSSVMVEPGNSDDHYIPEDEKINEITLISNEEEGFTLDPIDGLDIADRRKRKKRRLLIDPVKEISSKTMHKQLTSFMDTLMVLDLAPPTQRLMMWKKRGGVETLLSTATQDLINEDLKMLFANCFLSSDYKLAKLTLKESLRKEVGNQHILDPSVVEEPNSHSELGQPQDGKDVTDESMGSFQENINRNINSKQDILEMISPAAEGFSLVSASSAQENHPAELESSGSKQNTEAEKWNQRLFQTLNELREFNKMGMQFFSLIKLCRNSDRKQAAAKFYTLLILKKHRAIELSQSAPYADVIATVGPMFHKL", "length": 552 }, "evidence": [ { "id": "A0A8C2MZT7", "url": "https://omabrowser.org/oma/group/A0A8C2MZT7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H4I0-1", "protein_name": "Double-strand-break repair protein rad21-like protein 1", "gene_name": "RAD21L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFYTHVLMSKRGPLAKIWLAAHWEKKLTKAHVFECNLEITIEKILSPKVKIALRTSGHLLLGVVRIYNRKAKYLLADCSEAFLKMKMTFCPGLVDLPKENFEASYNAITLPEEFHDFDTQNMNAIDVSEHFTQNQSRPEEITLRENFDNDLIFQAESFGEESEILRRHSFFDDNILLNSSGPLIEHSSGSLTGERSLFYDSGDGFGDEGAAGEMIDNLLQDDQNILLEDMHLNREISLPSEPPNSLAVEPDNSECICVPENEKMNETILLSTEEEGFTLDPIDISDIAEKRKGKKRRLLIDPIKELSSKVIHKQLTSFADTLMVLELAPPTQRLMMWKKRGGVHTLLSTAAQDLIHAELKMLFTKCFLSSGFKLGRKMIQKESVREEVGNQNIVETSMMQEPNYQQELSKPQTWKDVIGGSQHSSHEDTNKNINSEQDIVEMVSLAAEESSLMNDLFAQEIEYSPVELESLSNEENIETERWNGRILQMLNRLRESNKMGMQSFSLMKLCRNSDRKQAAAKFYSFLVLKKQLAIELSQSAPYADIIATMGPMFYNI", "length": 556 }, "evidence": [ { "id": "A0A8C2MZT7", "url": "https://omabrowser.org/oma/group/A0A8C2MZT7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "meiotic cohesin complex", "id": "GO:0030893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030893", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZT7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZT7" } ], "pmid": "" }, { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZT7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZT7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZT7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZT7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZT7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZT7" } ], "pmid": "" }, { "name": "sister chromatid cohesion", "id": "GO:0007062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007062", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZT7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZT7" } ], "pmid": "" }, { "name": "replication-born double-strand break repair via sister chromatid exchange", "id": "GO:1990414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990414", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZT7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 452, "end_pos": 454, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MZT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZT7" }, { "id": "PF04824", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04824" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rad21/Rec8-like protein C-terminal eukaryotic", "eco_id": "ECO_0000259", "start_pos": 498, "end_pos": 549, "start_aa": "Gln", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MZT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZT7" }, { "id": "PF04825", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04825" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rad21/Rec8-like protein N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 100, "start_aa": "Met", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 178, "end_pos": 180 }, { "start_pos": 452, "end_pos": 454 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MZV0-1", "uniprot_ac": "A0A8C2MZV0", "uniprot_id": "A0A8C2MZV0_CRIGR", "mass": { "chemical_mass": 32981.0, "monoisotopic_mass": 32981.0 }, "refseq": { "ac": "XP_027245745", "name": "F-actin-capping protein subunit alpha-2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245745" }, "gene_names": [ { "name": "Capza2", "type": "recommended", "evidence": [ { "id": "A0A8C2MZV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZV0" } ] }, { "name": "Capza2", "type": "synonym", "evidence": [ { "id": "XP_027245745", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245745" } ] } ], "protein_names": [ { "name": "F-actin-capping protein subunit alpha", "type": "recommended", "evidence": [ { "id": "A0A8C2MZV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZV0/entry#names_and_taxonomy" } ] }, { "name": "F-actin-capping protein subunit alpha-2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027245745", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245745" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027245745", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245745" } ] }, { "annotation": "F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. 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This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027284271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284271" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZV4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100772540", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZV4", "locus": {} } ], "crossref": [ { "id": "cd01852", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01852", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772540", "url": "https://www.ncbi.nlm.nih.gov/gene/100772540", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006703", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006703", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772540", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772540", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WENEGCC", "url": "https://omabrowser.org/oma/group/WENEGCC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MZV4", "url": "https://www.orthodb.org/?gene=A0A8C2MZV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10903", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10903", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10903:SF144", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10903:SF144", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04548", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04548", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027284271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284271", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZV4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYQLHRGAESIGSYTMETFFWLLGSTYKKYCSLALPGKSEISRECNAAGDRKRSHSCLSVSPMVEEGECGHSPQKNPTRQVSLDSVQGLTKGLKEKEVSPKRLQILLVGKTGSGKSATGNSILGRQVFESKISARPVTRTFQKGSREWAGKELEVIDTPDILSPQDKPEVAAEKICGVLASPGPHVVLLVIQVGRYTAEDQEAARRLQEIFGKGILAYTILVFTRKEDLDEGSLEEYIQENNNKSLDDLDVACERRHCAFNNRARGHEQEKQLKDLMEKIEIILWENEGHCYTTELPNVSSKTV", "length": 304, "header": "tr|A0A8C2MZV4-1|A0A8C2MZV4_CRIGR Isoform 1 of GTPase IMAP family member 6 OS=Cricetulus griseus OX=10029 GN=LOC100772540 PE=3 SV=1 CANONICAL=A0A8C2MZV4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZV4/entry#A0A8C2MZV4-1", "sequence": { "sequence": "MYQLHRGAESIGSYTMETFFWLLGSTYKKYCSLALPGKSEISRECNAAGDRKRSHSCLSVSPMVEEGECGHSPQKNPTRQVSLDSVQGLTKGLKEKEVSPKRLQILLVGKTGSGKSATGNSILGRQVFESKISARPVTRTFQKGSREWAGKELEVIDTPDILSPQDKPEVAAEKICGVLASPGPHVVLLVIQVGRYTAEDQEAARRLQEIFGKGILAYTILVFTRKEDLDEGSLEEYIQENNNKSLDDLDVACERRHCAFNNRARGHEQEKQLKDLMEKIEIILWENEGHCYTTELPNVSSKTV", "length": 304, "header": "tr|A0A8C2MZV4-1|A0A8C2MZV4_CRIGR Isoform 1 of GTPase IMAP family member 6 OS=Cricetulus griseus OX=10029 GN=LOC100772540 PE=3 SV=1 CANONICAL=A0A8C2MZV4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N892-1", "uniprot_ac": "A0A8C2N892", "uniprot_id": "A0A8C2N892_CRIGR", "mass": { "chemical_mass": 95181.0, "monoisotopic_mass": 95181.0 }, "refseq": { "ac": "XP_027261271", "name": "rho GTPase-activating protein 12 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261271" }, "gene_names": [ { "name": "Arhgap12", "type": "recommended", "evidence": [ { "id": "A0A8C2N892", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892" } ] }, { "name": "Arhgap12", "type": "synonym", "evidence": [ { "id": "XP_027261271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261271" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein 12", "type": "recommended", "evidence": [ { "id": "A0A8C2N892", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892/entry#names_and_taxonomy" } ] }, { "name": "Rho-type GTPase-activating protein 12", "type": "synonym", "evidence": [ { "id": "A0A8C2N892", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 12 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027261271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261271" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027261271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261271" } ] }, { "annotation": "GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJI6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI6#function" }, { "database": "UniProtKB", "id": "ARBA00055252", "url": "https://www.uniprot.org/uniprotkb/ARBA00055252#function" }, { "database": "UniProtKB", "id": "A0A8C2MZW1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW1#function" }, { "database": "UniProtKB", "id": "A0A8C2N892", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N892", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Arhgap12", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892", "locus": {} } ], "crossref": [ { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04403", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04403", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12070", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12070", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13233", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13233", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770897", "url": "https://www.ncbi.nlm.nih.gov/gene/100770897", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770897", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770897", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PECHYAT", "url": "https://omabrowser.org/oma/group/PECHYAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N892", "url": "https://www.orthodb.org/?gene=A0A8C2N892", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JJI6", "url": "https://www.orthodb.org/?gene=A0A9J7JJI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23176", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23176", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23176:SF107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23176:SF107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16618", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16618", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027261271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261271", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZW1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N892", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N892-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FNA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FNA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJI6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAERSGKIAAGQVYIEVEYDYEYEAKDRKIVIRQGERYILVKKTNDDWWQVRLDENSKAFYVPAQYVKEVTRKALMPPVKQAAGLPNNSMKTIQSMHLQRSTENVNKMPELSSFGKPSSSVQGTGLTRDANQNFGSNYNSGQTLNLSLDLTHNNGKFNSDSHSPKVSSQNRTRLFGHFPGPEFLDVEKTSFSQEQSCDSAGEGSERTHQDSESGDELSSSSTEQMRATTPPSQGRPDSPVYANLQELKISQSALPPLPGSPAIQVNGEWETHKDSSGRCYYYNRATQERTWKPPRWARDTGTNRDFQSPGELEPFSSEENYHSSCYSQSDSQCGSPPRGWSEELDERGHTLYTSDYTKEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHSTIVLDTNDKESPTTTKNCLPENESSPTSSKHQDPGQEKYGLLNVTKITENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTINNQAAEADEAADEEAPDSPGVEKQDKEKDQKDLKKLRSMKGSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGCNLASLCQRENGTVPKFVKLCIEHVEEHGLDVDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVVTGALKMFFRELPEPLFTFNHFNDFVNAIKQDPRQRVTAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLKPERETGNIAVHTVYQNQIVELILLELSTIFGR", "length": 838, "header": "tr|A0A8C2N892-1|A0A8C2N892_CRIGR Isoform 1 of Rho GTPase-activating protein 12 OS=Cricetulus griseus OX=10029 GN=Arhgap12 PE=4 SV=1 CANONICAL=A0A8C2N892-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892/entry#A0A8C2MZW1-1", "sequence": { "sequence": "MAERSGKIAAGQVYIEVEYDYEYEAKDRKIVIRQGERYILVKKTNDDWWQVRLDENSKAFYVPAQYVKEVTRKALMPPVKQAAGLPNNSMKTIQSMHLQRSTENVNKMPELSSFGKPSSSVQGTGLTRDANQNFGSNYNSGQTLNLSLDLTHNNGKFNSDSHSPKVSSQNRTRLFGHFPGPEFLDVEKTSFSQEQSCDSAGEGSERTHQDSESGDELSSSSTEQMRATTPPSQGRPDSPVYANLQELKISQSALPPLPGSPAIQVNGEWETHKDSSGRCYYYNRATQERTWKPPRWARDTGTNRDFQSPGELEPFSSEENYHSSCYSQSDSQCGSPPRGWSEELDERGHTLYTSDYTKEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHSTIVLDTNDKGQEKYGLLNVTKITENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTINNQAAEADEAADEEAPDSPGVEKQDKEKDQKDLKKLRSMKGSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGCNLASLCQRENGTVPKFVKLCIEHVEEHGLDVDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVVTGALKMFFRELPEPLFTFNHFNDFVNAIKQDPRQRVTAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLKPERETGNIAVHTVYQNQIVELILLELSTIFGR", "length": 813, "header": "tr|A0A8C2MZW1-1|A0A8C2N892_CRIGR Computationally mapped isoform of Rho GTPase-activating protein 12 OS=Cricetulus griseus OX=10029 GN=Arhgap12 PE=4 SV=1 CANONICAL=A0A8C2N892-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N892-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892/entry#A0A8C2N892-1", "sequence": { "sequence": "MAERSGKIAAGQVYIEVEYDYEYEAKDRKIVIRQGERYILVKKTNDDWWQVRLDENSKAFYVPAQYVKEVTRKALMPPVKQAAGLPNNSMKTIQSMHLQRSTENVNKMPELSSFGKPSSSVQGTGLTRDANQNFGSNYNSGQTLNLSLDLTHNNGKFNSDSHSPKVSSQNRTRLFGHFPGPEFLDVEKTSFSQEQSCDSAGEGSERTHQDSESGDELSSSSTEQMRATTPPSQGRPDSPVYANLQELKISQSALPPLPGSPAIQVNGEWETHKDSSGRCYYYNRATQERTWKPPRWARDTGTNRDFQSPGELEPFSSEENYHSSCYSQSDSQCGSPPRGWSEELDERGHTLYTSDYTKEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHSTIVLDTNDKESPTTTKNCLPENESSPTSSKHQDPGQEKYGLLNVTKITENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTINNQAAEADEAADEEAPDSPGVEKQDKEKDQKDLKKLRSMKGSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGCNLASLCQRENGTVPKFVKLCIEHVEEHGLDVDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVVTGALKMFFRELPEPLFTFNHFNDFVNAIKQDPRQRVTAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLKPERETGNIAVHTVYQNQIVELILLELSTIFGR", "length": 838, "header": "tr|A0A8C2N892-1|A0A8C2N892_CRIGR Isoform 1 of Rho GTPase-activating protein 12 OS=Cricetulus griseus OX=10029 GN=Arhgap12 PE=4 SV=1 CANONICAL=A0A8C2N892-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FNA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892/entry#A0A9J7FNA7-1", "sequence": { "sequence": "MAERSGKIAAGQVYIEVEYDYEYEAKDRKIVIRQGERYILVKKTNDDWWQVRLDENSKAFYVPAQYVKEVTRKALMPPVKQAAGLPNNSMKTIQSMHLQRSTENVNKMPELSSFGKPSSSVQGTGLTRDANQNFGSNYNSGQTLNLSLDLTHNNGKFNSDSHSPKVSSQNRTRLFGHFPGPEFLDVEKTSFSQEQSCDSAGEGSERTHQDSESGDELSSSSTEQMRWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHSTIVLDTNDKESPTTTKNCLPENESSPTSSKHQDPGQEKYGLLNVTKITENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTINNQAAEADEAADEEAPDSPGVEKQDKEKDQKDLKKLRSMKGSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGCNLASLCQRENGTVPKFVKLCIEHVEEHGLDVDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVVTGALKMFFRELPEPLFTFNHFNDFVNAIKQDPRQRVTAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLKPERETGNIAVHTVYQNQIVELILLELSTIFGR", "length": 704, "header": "tr|A0A9J7FNA7-1|A0A8C2N892_CRIGR Computationally mapped isoform of Rho GTPase-activating protein 12 OS=Cricetulus griseus OX=10029 GN=Arhgap12 PE=4 SV=1 CANONICAL=A0A8C2N892-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892/entry#A0A9J7JJI6-1", "sequence": { "sequence": "MAERSGKIAAGQVYIEVEYDYEYEAKDRKIVIRQGERYILVKKTNDDWWQVRLDENSKAFYVPAQYVKEVTRKALMPPVKQAAGLPNNSMKTIQSMHLQRSTENVNKMPELSSFGKPSSSVQGTGLTRDANQNFGSNYNSGQTLNLSLDLTHNNGKFNSDSHSPKVSSQNRTRLFGHFPGPEFLDVEKTSFSQEQSCDSAGEGSERTHQDSESGDELSSSSTEQMRATTPPSQGRPDSPVYANLQELKISQSALPPLPGSPAIQVNGEWETHKDSSGRCYYYNRATQERTWKPPRWARDTGTNRDFQSPGELEWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHSTIVLDTNDKGQEKYGLLNVTKITENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTINNQAAEADEAADEEAPDSPGVEKQDKEKDQKDLKKLRSMKGSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGCNLASLCQRENGTVPKFVKLCIEHVEEHGLDVDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVVTGALKMFFRELPEPLFTFNHFNDFVNAIKQDPRQRVTAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLKPERETGNIAVHTVYQNQIVELILLELSTIFGR", "length": 766, "header": "tr|A0A9J7JJI6-1|A0A8C2N892_CRIGR Computationally mapped isoform of Rho GTPase-activating protein 12 OS=Cricetulus griseus OX=10029 GN=Arhgap12 PE=4 SV=1 CANONICAL=A0A8C2N892-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJI6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJI6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770897", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770897", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZJ58-1", "protein_name": "Rho GTPase-activating protein 12", "gene_name": "ARHGAP12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADRGGKIVPGQVYIEVEYDYEYEAKDRKIVIKQGERYILVKKTNDDWWQVKPDENSKAFYVPAQYVKEVGRKALMPPVKQAAGLPNNSVKMMQSLHLQRSTENVNKLPELSSFGKPSAAVQGSGLIRDANQNFGPSYIPGQTHNLSLDLTHNNGKFNSDSHSPKVPGQNRTRLFGHFPGPEFLDIEKTSFSQEQSCDSAGEGSERIQQDSESGDELSSSSTEQIRATTPPNQGRPDSPVYANLQELKISQSALPPLPGSPAIQINGEWETHKDSSGRCYYYNRGTQERTWKPPRSTRDTNISKGDFQSPGDQELLSSEENYQSICYSQSDSQCGSPPRGWSEELDERGHTLYTSDYTNEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHSTIVLDTNDKPLLPLLHLPCFHGVLPVFPTFTQGQEKYGLLNVTKISENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLRGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTISNQVVEPDEAIEEETPDSPGIEKHDREKDHKDPKKFRSTKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGANLANLCQRENSTVPKFVKLCIEHVEEYGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVSAVKDLIRQLPKPNQDTMQILFRHLKRVIENGERNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLEINSIFGR", "length": 837 }, "evidence": [ { "id": "A0A8C2N892", "url": "https://omabrowser.org/oma/group/A0A8C2N892/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AC58GV37-1", "protein_name": "Rho GTPase-activating protein 12b isoform X1", "gene_name": "arhgap12b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSERDGRCDLSIAPGQVYIEVEYDYEYKAKDKLISIRQGECYMLVRKTNEDWWQVRREEGTKAFYVPAQYVREVRRALMPPPKPRAKPPNVLEITHCRSSNENLNQRAPTEKSTFGRPPPSTTPSPLPGQQTPPLLLRDSNHNPGMKSVVAELTLLNNNNHHNFHHANPTLPQGRAESPPRDQGCQGKLTGGLSVDTDGSVSPGDGVEKMRNDSESGDELSSSSTEHIQSVSLSGQGRPESPVYTNLQELKICQSSVPPVPSTSPLHVLGDWETHKDTSGRNFYFNRTTQERTWKPPRSRDNGVSRGDTSNTGDMEPLSSEENCPSTHSSQSDSQYGSPPRGWSEELDEHGHTLYVSEYTNEKWIKHVDEQGRPYYYSADGSRSEWELPKYNLSPPISGEAPKSHSLERKQQEPIVLTKWRHSTYVLDISDKTTWFYLFANKKLPFKNRWFSVNHPPRGFGLPVYREPSEKCGVLNVTKITEHGKKVRKNWASTWTVLQGSSLLFAKGQGSGTSWSYCHNGSFPELLLSLLSNWKRSIKPRPAVSYTHCRRARASSFGGNQSKPEFTVDLRGGSVEWASKEKSSKKHVIELKTRVGTELLIQSEIDSVINDWFRALSETINTHAWESDEAIEEDMPESPGSEKHDKEKDPRDSKKNRVVKNSSMESSEQKKTRVKLKKFLTRRPTLQAVRDKGYIKDQVFGCSLTALCQREGTSVPNFVKMCIEHVENTGLNVDGLYRVSGNLAVIQKLRFAVNHDEKVNLDDSKWEDIHVTTGALKMLFRELPEPLFTYASFNDFVEAIKNSDYKQRVQSIKDLIKQLPKPNQETMKVLFKHLKRVIDHGEVNRMTTQSVAIVFGPTLLRPEIETGNMAVHMVYQNQIVELILLEYENIFGR", "length": 893 }, "evidence": [ { "id": "A0A8C2N892", "url": "https://omabrowser.org/oma/group/A0A8C2N892/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZDI5-1", "protein_name": "Rho GTPase-activating protein 12", "gene_name": "Arhgap12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAERSGKIASGQVYIEVEYDYEYEAKDRKIVIRQGERYLLVKKTNDDWWQVRLDENSKAFYVPAQYVKEVTRKALMPPVKQTTGLPNNSMKTTQSMHLQRSTENVNKMPELSSFGKPSSSVQGTGLIRDANQNFGSNYNSGQTLNLSLDLTHNNGKFNSDSHSPKVSSQNRTRLFGHFPGPEFLDIEKTSFSQEQSCDSAGEGSERTHQDSESGDELSSSSTEQMRATTPPNQGRPDSPVYANLQELKISQSALPPLPGSPAIQVNGEWETHKDSSGRCYYYNRTTQERTWKPPRWARDVSTSRDFQSPGEQEPLSSEENYHSSCFSQSDSQCGSPPRGWSEELDERGHTLYTSDYTKEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHSTIVLDSNDKDSPTSTKLCLPENESPPTSTKHQDPGQEKYGLLNVTKITENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGAAIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTINNQVAEADEAAEEEAPDSPGVEKQDKEKDQKELKKLRSMKGSSMDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDVDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVTAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLKPERETGNIAVHTVYQNQIVELILLELSTVFGR", "length": 838 }, "evidence": [ { "id": "A0A8C2N892", "url": "https://omabrowser.org/oma/group/A0A8C2N892/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C0D4-1", "protein_name": "Rho GTPase-activating protein 12", "gene_name": "Arhgap12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAERSGKITAGQAYIEVEYDYEYDAKDRKIVIRQGERYLLVKKTNDDWWQVRPDENSKAFYVPAQYVKEVTRKALMPPVKQATGLPNNSMKTIQSMHLQRSTENVNKMPELSSFGKPSSSVQGTGLIRDANQNFGSNYNSGQTLNLSLDLTHNNGKFNSDSHSPKVSSQNRTRLFGHFPGPEFLDIEKTSFSQEQSCDSAGEGSERIQQDSESGDELSSSSTEQMRATTPPNQGRPDSPVYANLQELKISQSALPPLPGSPAIQVNGEWETHKDSSGRCYYYNRTTQERTWKPPRWARDVSTSRDFQSPGEQEPLSSEENYHSSCFSQSDSQCGSPPRGWSEELDERGHTLYTSDYTKEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHSTIVLDSNDKDSPTTTKLCLPENESPPTSSKHQDPGQEKYGLLNVTKITENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGAVIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTINNQVAEADEAAEEETPDSPGVEKHDKEKDQKELKKLRSMKGSSMDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDVDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVTAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLKPERETGNIAVHTVYQNQIVELILLELSTVFGR", "length": 838 }, "evidence": [ { "id": "A0A8C2N892", "url": "https://omabrowser.org/oma/group/A0A8C2N892/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWW6-1", "protein_name": "Rho GTPase-activating protein 12", "gene_name": "ARHGAP12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMADRSGKIIPGQVYIEVEYDYEYEAKDRKIVIKQGERYILVKKTNDDWWQVKPDENSKAFYVPAQYVKEVTRKALMPPVKQVAGLPNNSTKIMQSLHLQRSTENVNKLPELSSFGKPSSSVQGTGLIRDANQNFGPSYNQGQTVNLSLDLTHNNGKFNNDSHSPKVSSQNRTRSFGHFPGPEFLDVEKTSFSQEQSCDSAGEGSERIHQDSESGDELSSSSTEQIRATTPPNQGRPDSPVYANLQELKISQSALPPLPGSPAIQINGEWETHKDSSGRCYYYNRGTQERTWKPPRWTRDASISKGDFQNPGDQELLSSEENYYSTSYSQSDSQCGSPPRGWSEELDERGHTLYTSDYTNEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHSTIVLDTNDKESPTASKPCFPENESSPSSPKHQDTASSPKDQEKYGLLNVTKIAENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPDSPGIEKHDKEKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLELSSIFGR", "length": 846 }, "evidence": [ { "id": "A0A8C2N892", "url": "https://omabrowser.org/oma/group/A0A8C2N892/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N892", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N892", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N892", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" }, { "start_pos": 658, "end_pos": 660, "annotation": "n_glycosylation_sequon" }, { "start_pos": 708, "end_pos": 710, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N892", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 466, "end_pos": 567, "start_aa": "Lys", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N892", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 648, "end_pos": 836, "start_aa": "Cys", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N892", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 72, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N892", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N892" }, { "id": "PS50020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WW", "eco_id": "ECO_0000259", "start_pos": 263, "end_pos": 296, "start_aa": "Ile", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 170, "end_pos": 172 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 442, "end_pos": 444 }, { "start_pos": 463, "end_pos": 465 }, { "start_pos": 506, "end_pos": 508 }, { "start_pos": 658, "end_pos": 660 }, { "start_pos": 708, "end_pos": 710 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2MZW4-1", "uniprot_ac": "A0A8C2MZW4", "uniprot_id": "A0A8C2MZW4_CRIGR", "mass": { "chemical_mass": 39170.0, "monoisotopic_mass": 39170.0 }, "refseq": { "ac": "XP_027292344", "name": "TBC1 domain family member 21 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027292344" }, "gene_names": [ { "name": "Tbc1d21", "type": "recommended", "evidence": [ { "id": "A0A8C2MZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4" } ] }, { "name": "Tbc1d21", "type": "synonym", "evidence": [ { "id": "XP_027292344", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027292344" } ] } ], "protein_names": [ { "name": "TBC1 domain family member 21", "type": "recommended", "evidence": [ { "id": "A0A8C2MZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4/entry#names_and_taxonomy" } ] }, { "name": "Male germ cell Rab GTPase-activating protein", "type": "synonym", "evidence": [ { "id": "A0A8C2MZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4/entry#names_and_taxonomy" } ] }, { "name": "TBC1 domain family member 21 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027292344", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027292344" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613894.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027292344.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027292344", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027292344" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tbc1d21", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4", "locus": {} } ], "crossref": [ { "id": "100753805", "url": "https://www.ncbi.nlm.nih.gov/gene/100753805", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753805", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753805", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NIACDIQ", "url": "https://omabrowser.org/oma/group/NIACDIQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MZW4", "url": "https://www.orthodb.org/?gene=A0A8C2MZW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957:SF489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957:SF489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027292344", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027292344", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GX58", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GX58-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZI1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTLSPENSLSARRSATFILEKRNPPIDKTEWDSFFDENGHLAKTRDFICVNILERGLHPFVRTEAWKFLTGYYSWQSSRDERLMVDANRRRNYKVLCQMYEKIRPLLENLHGNFTETRNNIAYDIQKLYDKDPLGNVLVDKKKLEKTLLLSYVCNTKAEYQRGFHEMVMLFQLMVEHDHETFWLFQFFLQKTEHSCVINIGVGKNLDMLNSLIALLDPEFAEHLKGKGSGAVQSLFPWFCLCFQRAFKSFDDVWRLWEVLLTGKPCRNFQVLVAYSMLQMVREQALLESMSGDAILLACNNLIDLDADELISAACLVYAELMQKEIPGPLKDFFL", "length": 336, "header": "tr|A0A8C2MZW4-1|A0A8C2MZW4_CRIGR Isoform 1 of TBC1 domain family member 21 OS=Cricetulus griseus OX=10029 GN=Tbc1d21 PE=4 SV=1 CANONICAL=A0A8C2MZW4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4/entry#A0A8C2MZW4-1", "sequence": { "sequence": "MTTLSPENSLSARRSATFILEKRNPPIDKTEWDSFFDENGHLAKTRDFICVNILERGLHPFVRTEAWKFLTGYYSWQSSRDERLMVDANRRRNYKVLCQMYEKIRPLLENLHGNFTETRNNIAYDIQKLYDKDPLGNVLVDKKKLEKTLLLSYVCNTKAEYQRGFHEMVMLFQLMVEHDHETFWLFQFFLQKTEHSCVINIGVGKNLDMLNSLIALLDPEFAEHLKGKGSGAVQSLFPWFCLCFQRAFKSFDDVWRLWEVLLTGKPCRNFQVLVAYSMLQMVREQALLESMSGDAILLACNNLIDLDADELISAACLVYAELMQKEIPGPLKDFFL", "length": 336, "header": "tr|A0A8C2MZW4-1|A0A8C2MZW4_CRIGR Isoform 1 of TBC1 domain family member 21 OS=Cricetulus griseus OX=10029 GN=Tbc1d21 PE=4 SV=1 CANONICAL=A0A8C2MZW4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GX58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4/entry#A0A9J7GX58-1", "sequence": { "sequence": "MTTLSPENSLSARRSATFILGLHPFVRTEAWKFLTGYYSWQSSRDERLMVDANRRRNYKVLCQMYEKIRPLLENLHGNFTETRNNIAYDIQKLYDKDPLGNVLVDKKKLEKTLLLSYVCNTKAEYQRGFHEMVMLFQLMVEHDHETFWLFQFFLQKTEHSCVINIGVGKNLDMLNSLIALLDPEFAEHLKGKGSGAVQSLFPWFCLCFQRAFKSFDDVWRLWEVLLTGKPCRNFQVLVAYSMLQMVREQALLESMSGDAILLACNNLIDLDADELISAACLVYAELMQKEIPGPLKDFFL", "length": 300, "header": "tr|A0A9J7GX58-1|A0A9J7GX58_CRIGR Computationally mapped isoform of TBC1 domain family member 21 OS=Cricetulus griseus OX=10029 GN=Tbc1d21 PE=4 SV=1 CANONICAL=A0A8C2MZW4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4/entry#A0A9J7GZI1-1", "sequence": { "sequence": "MTTLSPENSLSARRSATFILEKRNPPIDKTEWDSFFDENGHLAKTRDFICVNILERGLHPFVRTEAWKFLTGYYSWQSSRDERLMVDANRRRNYKVLCQMYEKIRPLLENLHGNFTETRNNIAYDIQKLYDKDPLGNVLVDKKKLEKTLLLSYVCNTKAEYQRGFHEMVMLFQLMVEHDHETFWLFQFFLQKTEHSCVINIGVGKNLDMLNSLIALLDPEFAEHLRKGSGAVQSLFPWFCLCFQRAFKSFDDVWRLWEVLLTGKPCRNFQVLVAYSMLQMVREQALLESMSGDAILLACNNLIDLDADELISAACLVYAELMQKEIPGPLKDFFL", "length": 335, "header": "tr|A0A9J7GZI1-1|A0A9J7GZI1_CRIGR Computationally mapped isoform of TBC1 domain family member 21 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tbc1d21 PE=4 SV=1 CANONICAL=A0A8C2MZW4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753805", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753805", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TLT3-1", "protein_name": "TBC1 domain family member 21", "gene_name": "TBC1D21", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTTLSPENSLSARQSASFILVKRKPPIDKTEWDGFFDENGHLAKSRDFICVNILERGLHPFVRTEAWKFLTGYYSWQSSQDERLTVDSTRRKNYEALCQMYEKIQPLLENLHRNFTETRNNITYDIQKLYDKDPLGNVLIDKKRLEKILLLSYVCNTEAEYQQGFHDMVMLFHLMVEHDHETFWLFQFFLQKTEHSCVINIGVGKNLDMLNILINFLDPVFSDHLKGKGAGAVQSLFPWFCLCFQHAFKSFDDVWRLWEVLLTGKPCRNSQVLVAYSMLQMVREQVLQESMTGDDILLACNNLIDLDADELISAACIVYAELIQKDVPQPLKDFLL", "length": 336 }, "evidence": [ { "id": "A0A8C2MZW4", "url": "https://omabrowser.org/oma/group/A0A8C2MZW4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9SBL3-1", "protein_name": "TBC1 domain family member 21", "gene_name": "TBC1D21", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTTLSPENSLSARQSASFILVKRKPPIDKTEWDGFFDENGHLAKSRDFICVNILERGLHPTVRTEAWKFLTGYYSWQSSQDERLTVDSTRRKNYEALCQMYQKIQPLLENLHRNFIETRNSITYDIKKLYDKDPLGNVLLDKKRLEKILLLSYVCNTQAEYQQGFHEMVMIFQLMVEHDHETFWLFQFFLQKTEHSCVINIGVGKNLDMLNTLINFLDPVFAEHLKGKGAGAVPSLFPWFCLCFQRAFKTFDDVWRLWEVLLTGKPCRNFQVLVAYSMLQMVRQQVLQESMTGDDILLACNNLIDLDADELISAACIVYAELIQKDVPQSLKDFFL", "length": 336 }, "evidence": [ { "id": "A0A8C2MZW4", "url": "https://omabrowser.org/oma/group/A0A8C2MZW4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E9PT72-1", "protein_name": "TBC1 domain family member 21", "gene_name": "Tbc1d21", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTLSPENSLSARRSATFILEKKNPPIDKAEWDSFFDENGHLAKSRDFICVNILERGLHPLVRADAWKFLTGYYSWQSSRDERLMVDSNRRRNYNSLCQMYEKIQPLLENLHGNFTETRNNIVYDIQKLYDKDPLGNVLVDKKKLEKTLLLSYVCNTKAEYQRGFHEMVMLFQLMVEHDHETFWLFQFFLQKTEHSCVINIGVGKNLDMLNNLITLLDPQFADHLKGKGSGAVQSLFPWFCLCFQRAFKSFDDVWRLWEVLLTGKPCRNFQVLVAYSMLQMVREQALLECMSGDAILMACNKLIDLDADELISAACVVYSELIQKEVPQALKDFFL", "length": 336 }, "evidence": [ { "id": "A0A8C2MZW4", "url": "https://omabrowser.org/oma/group/A0A8C2MZW4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IYX1-1", "protein_name": "TBC1 domain family member 21", "gene_name": "TBC1D21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTLSPENSLSARQSASFILVKRKPPIDKTEWDSFFDESGHLAKSRDFICVNILERGLHPFVRTEAWKFLTGYFSWQSSQDERLTVDSMRRKNYKALCQMYEKIQPLLENLHRNFTETRNNIARDIQKIYDKDPLGNVLIDKKRLEKILLLSYVCNTQAEYQQGFHEMMMLFQLMVEHDHETFWLFQFFLQKTEHSCVINIGVAKNLDMLSTLITFLDPVFAEHLKGKGAGAVQSLFPWFCFCFQRAFKSFDDVWRLWEVLLTGKPCRNFQVLVAYSMLQMVREQVLQESMGGDDILLACNNLIDLDADELISAACVVYAELIQKDVPQTLKDFFL", "length": 336 }, "evidence": [ { "id": "A0A8C2MZW4", "url": "https://omabrowser.org/oma/group/A0A8C2MZW4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D9D3-1", "protein_name": "TBC1 domain family member 21", "gene_name": "Tbc1d21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTLSPENSLSARRSATFILEKRNPPIDKAEWDSFFDENGHLAKSRDFICINILERGLHPFVRTEAWKFLTGYYSWQSSRDERLMVDSNRRRNYNSLCQMYEKIQPLLENLHGNFTETRNNIAYDIQRLYDKDPLGNVLIDKKKLEKTLLLSYVCNTKAEYQRGFHEMVMLFQLMVEHDHETFWLFQFFLQKTEHSCVINIGVGKNLDMLNSLITLLDPEFAEHLKGKGSGAVQSLFPWFCLCFQRAFKTFDDVWRLWEVLLTGKPCRNFQVLVAYSMLQMVREQALLECMSGDAILMACNNLIDLDADELISAACVVYSELMQKEVPQPLKEFLL", "length": 336 }, "evidence": [ { "id": "A0A8C2MZW4", "url": "https://omabrowser.org/oma/group/A0A8C2MZW4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4" } ], "pmid": "" }, { "name": "sperm mitochondrial sheath assembly", "id": "GO:0120317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120317", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZW4" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 265, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"MAAAARSRIAHLLRHLQSTACQCPTHSHTYSQAPGLSPSGKTTDYAFEMAVSNIRYGAGVTKEVGMDLQNMGAKKVCLMTDKNLSQLPPVQTVMDSLVKSGISFQVYDSVRVEPTDGSFMDAIEFAKKGAFDAYVAVGGGSTMDTCKAANLYASSPHSEFLDYVNAPIGKGKPVTVPLKPLIAVPTTSGTGSETTGVAIFDYEHMKVKTGIASRAIKPTLGLVDPLHTLHMPCQVVANSGFDVLCHALESYTAIPYNMRSPCPSNPIQRPAYQGSNPISDIWAVHALRIVAKYLKRAVKNPDDLEARSSMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYKAKEYNVDHPLVPHGLSVVLTSPAVFTFTAQMFPERHLETAEILGADIRTARTQDAGPVLADTLRQFLFDLKVDDGLGALGYSKDDIPSLVKGTLPQERVTKLAPRAQSEEDLSALFEASMKLY", "length": 467, "header": "tr|A0A8C2N001-1|A0A8C2N001_CRIGR Isoform 1 of Hydroxyacid-oxoacid transhydrogenase, mitochondrial OS=Cricetulus griseus OX=10029 GN=Adhfe1 PE=3 SV=1 CANONICAL=A0A8C2N001-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N001-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N001/entry#A0A8C2N001-1", "sequence": { "sequence": 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"MAVSNIRYGAGVTKEVGMDLQNMGAKKVCLMTDKNLSQLPPVQTVMDSLVKSGISFQVYDSVRVEPTDGSFMDAIEFAKKGAFDAYVAVGGGSTMDTCKAANLYASSPHSEFLDYVNAPIGKGKPVTVPLKPLIAVPTTSGTGSETTGVAIFDYEHMKVKTGIASRAIKPTLGLVDPLHTLHMPCQVVANSGFDVLCHALESYTAIPYNMRSPCPSNPIQRPAYQGSNPISDIWAVHALRIVAKYLKRAVKNPDDLEARSSMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYKAKEYNVDHPLVPHGLSVVLTSPAVFTFTAQMFPERHLETAEILGADIRTARTQDAGPVLADTLRQFLFDLKVDDGLGALGYSKDDIPSLVKGTLPQERVTKLAPRAQSEEDLSALFEASMKLY", "length": 419, "header": "tr|A0A9J7K4T3-1|A0A8C2N001_CRIGR Computationally mapped isoform of Hydroxyacid-oxoacid transhydrogenase, mitochondrial OS=Cricetulus griseus OX=10029 GN=Adhfe1 PE=3 SV=1 CANONICAL=A0A8C2N001-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 115, "start_aa": "Thr", "end_pos": 115, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr115", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K4T3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4T3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K4T3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4T3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764101", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764101", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "hydroxyacid-oxoacid transhydrogenase activity", "id": "GO:0047988", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047988", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N001", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N001" } ], "pmid": "" }, { "name": "alcohol dehydrogenase (NAD+) activity", "id": "GO:0004022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004022", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N001", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N001" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N001", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N001" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N001", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N001" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N001", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N001" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ketone body catabolic 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"enzyme_list": [ "A0A8C2N001-1" ], "evidence": [ { "id": "24734", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24734" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8C2N001", "gene_name": "Adhfe1", "activity": [ { "ec_number": "1.1.99.24", "activity": "4-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + succinate semialdehyde.", "evidence": [ { "id": "A0A8C2N001", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N001" } ] }, { "ec_number": "1.1.99.24", "activity": "", "evidence": [ { "id": "A0A8C2N001", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N001" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N001", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N001" }, { "id": "PF00465", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00465" } ], "ann_type": 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"https://www.rhea-db.org/rhea/?query=ec:1.1.99.24" }, { "id": "1.1.99.24", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.1.99.24" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 115 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { 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"count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N010-1", "uniprot_ac": "A0A8C2N010", "uniprot_id": "A0A8C2N010_CRIGR", "mass": { "chemical_mass": 26144.0, "monoisotopic_mass": 26144.0 }, "refseq": { "ac": "XP_027283320", "name": "PDZ and LIM domain protein 4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283320" }, "gene_names": [ { "name": "Pdlim4", "type": "recommended", "evidence": [ { "id": "A0A8C2N010", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N010" } ] }, { "name": "Pdlim4", "type": "synonym", "evidence": [ { "id": "XP_027283320", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283320" } ] } ], "protein_names": [ { "name": "PDZ and LIM domain protein 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027283320", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283320" }, { "id": "A0A8C2N010", 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This record is derived from a genomic sequence (NW_003614083.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504751", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504751" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N099", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rasal3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099", "locus": {} } ], "crossref": [ { "id": "cd05136", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05136", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13374", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13374", "database": "CDD", 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"https://www.ebi.ac.uk/interpro/entry/IPR039360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772454", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772454", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TWGSRSQ", "url": "https://omabrowser.org/oma/group/TWGSRSQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N099", "url": "https://www.orthodb.org/?gene=A0A8C2N099", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10194", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10194", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10194:SF96", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10194:SF96", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00616", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00616", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25321", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25321", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504751", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504751", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N099", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N099-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZR8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3S9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTECGQTMRRTVTFWSRSRDSAMDPPLPSEAAQTPPSPLTSYRWHTGGGGEKAAGGFRWGRFTGWGRTLSHQEPMVSSQPASRSLFRRVLSAPPKESRPNRLRISKSLWGRHKNAAPPEPKPNPKTPEPEPELVAAPEVPVAQIPEPPTPDMPVWDIGGFTLIEGKLVLFGEEEGPHQIRMGSASSETSIQASMGNLRDPDRTPGKTEPEATGSNQVHNVRGLLKRLKEKKRAKSELGAHGPRDGPPSALGSRESLATLSELDLGAERDVRVWPLHPSLLGEPYCFQVTWEGGSRCFCCRSSSERDRWIEDLRRQFQPSQDNVERQETWLTVWVHEAKGLPRAATPGVRAELWLDGALLARTAPRAGPGQLFWAERFHFEALPPARRLSLRLRGAGPAGATVGRVTLELDEVSIPRAPAAGLERWFPVLGAPTGAALRARIRVRRLRVLPSERYKELAEFLTFHYTRLCEALESTLSAQAKEELAAAMVRVLRATGRAQALVTDLGTAELVRCGGREALLFRENTLATKAIDEYMKLVAQEYLQETLGEVVRCLCASTEDCEVDPSKCPAPELSKHQARLRNSCERVFETIIHSYNWFPAELGNVFSSWREACRARGSEALGPRLVCASLFLRLLCPAILAPSLFGLVPEHPAPGPARTLTLIAKVIQNLANRAPFGEKEAYMAFMNSFLEDHGPAMQHFLDQVAVVDANATSSGYQGSGDLALQLAVLHVQLCTIFAELDQTTQDSLEPLPTILRAIEEGRPVPVSVPMRLPRITNQVHSSFSSGEKPGFLAPRDLPKHTPLVSKSQSLRSFQGAGSWARRRPDEERSQQRPRRVQRTQSVPARRPARRRPSAGPRTRPKDSLRTGPAPCGQTWTGASASLPRKPSVPWQRQLDQPRDRYQPLGTHRPVSKLAEIQCEVAALREEQKALSRLVESLSAHIQALTEQQEQLRCQLQDLDSRLGAGISKLDSEGGLPSNGSHRLKSLEHRLTEMECTQDQLRDALHSLQLLSGTPGSWSQPLPLKTACVNGAELSMGT", "length": 1038, "header": "tr|A0A8C2N099-1|A0A8C2N099_CRIGR Isoform 1 of RAS protein activator like-3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Rasal3 PE=4 SV=1 CANONICAL=A0A8C2N099-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N099-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099/entry#A0A8C2N099-1", "sequence": { "sequence": 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"length": 1038, "header": "tr|A0A8C2N099-1|A0A8C2N099_CRIGR Isoform 1 of RAS protein activator like-3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Rasal3 PE=4 SV=1 CANONICAL=A0A8C2N099-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099/entry#A0A9J7GZR8-1", "sequence": { "sequence": "MDPPLPSEAAQTPPSPLTSYRWHTGGGGEKAAGGFRWGRFTGWGRTLSHQEPMVSSQPASRSLFRRVLSAPPKESRPNRLRISKSLWGRHKNAAPPEPKPNPKTPAFPLVPEPEPELVAAPEVPVAQIPEPPTPDMPVWDIGGFTLIEGKLVLFGEEEGPHQIRMGSASSETSIQASMGNLRDPDRTPGKTEPEATGSNQVHNVRGLLKRLKEKKRAKSELGAHGPRDGPPSALGSRESLATLSELDLGAERDVRVWPLHPSLLGEPYCFQVTWEGGSRCFCCRSSSERDRWIEDLRRQFQPSQDNVERQETWLTVWVHEAKGLPRAATPGVRAELWLDGALLARTAPRAGPGQLFWAERFHFEALPPARRLSLRLRGAGPAGATVGRVTLELDEVSIPRAPAAGLERWFPVLGAPTGAALRARIRVRRLRVLPSERYKELAEFLTFHYTRLCEALESTLSAQAKEELAAAMVRVLRATGRAQALVTDLGTAELVRCGGREALLFRENTLATKAIDEYMKLVAQEYLQETLGEVVRCLCASTEDCEVDPSKCPAPELSKHQARLRNSCERVFETIIHSYNWFPAELGNVFSSWREACRARGSEALGPRLVCASLFLRLLCPAILAPSLFGLVPEHPAPGPARTLTLIAKVIQNLANRAPFGEKEAYMAFMNSFLEDHGPAMQHFLDQVAVVDANATSSGYQGSGDLALQLAVLHVQLCTIFAELDQTTQDSLEPLPTILRAIEEGRPVPVSVPMRLPRITNQVHSSFSSGEKPGFLAPRDLPKHTPLVSKSQSLRSFQGAGSWARRRPDEERSQQRPRRVQRTQSVPARRPARRRPSAGPRTRPKDSLRTGPAPCGQTWTGASASLPRKPSVPWQRQLDQPRDRYQPLGTHRPVSKLAEIQCEVAALREEQKALSRLVESLSAHIQALTEQQEQLRCQLQDLDSRLGAGISKLDSEGGLPSNGSHRLKSLEHRLTEMECTQDQLRDALHSLQLLSGTPGSWSQPLPLKTACVNGAELSMGT", "length": 1021, "header": "tr|A0A9J7GZR8-1|A0A9J7GZR8_CRIGR Computationally mapped isoform of RAS protein activator like-3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Rasal3 PE=4 SV=1 CANONICAL=A0A8C2N099-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H3S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099/entry#A0A9J7H3S9-1", "sequence": { "sequence": "MDPPLPSEAAQTPPSPLTSYRWHTGGGGEKAAGGFRWGRFTGWGRTLSHQEPMVSSQPASRSLFRRVLSAPPKESRPNRLRISKSLWGRHKNAAPPEPKPNPKTPAFPLVPEPEPELVAAPEVPVAQIPEPPTPDMPVWDIGGFTLIEGKLVLFGEEEGPHQIRMGSASSETSIQASMGNLRDPDRTPGKTEPEATGSNQVHNVRGLLKRLKEKKRAKPPSALGSRESLATLSELDLGAERDVRVWPLHPSLLGEPYCFQVTWEGGSRCFCCRSSSERDRWIEDLRRQFQPSQDNVERQETWLTVWVHEAKGLPRAATPGVRAELWLDGALLARTAPRAGPGQLFWAERFHFEALPPARRLSLRLRGAGPAGATVGRVTLELDEVSIPRAPAAGLERWFPVLGAPTGAALRARIRVRRLRVLPSERYKELAEFLTFHYTRLCEALESTLSAQAKEELAAAMVRVLRATGRAQALVTDLGTAELVRCGGREALLFRENTLATKAIDEYMKLVAQEYLQETLGEVVRCLCASTEDCEVDPSKCPAPELSKHQARLRNSCERVFETIIHSYK", "length": 569, "header": "tr|A0A9J7H3S9-1|A0A9J7H3S9_CRIGR Computationally mapped isoform of RAS protein activator like-3 isoform X3 OS=Cricetulus griseus OX=10029 GN=Rasal3 PE=4 SV=1 CANONICAL=A0A8C2N099-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 150, "start_aa": "Thr", "end_pos": 150, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr150", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 346, "start_aa": "Thr", "end_pos": 346, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr346", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N099", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N099", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772454", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772454", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6QQ91-1", "protein_name": "RAS protein activator like-3", "gene_name": "RASAL3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPPSPSRASQTQPVAPSPLTSYRWHSGGGAEKGAGGFRWGRLAGWGRAQSHQETTASSQPAPRSLFRRVLSAPPKESRTSRLKISKSLWGKNKSPPLDSEPEPENPEPEPELEPLATQIPEAPTPDVPVWNIEAFTLLDGKLVLLGNEDEGPRQPRMGSASSESSIHVASGNLKDPDRTPGKTDPEAAGPHQIHNVRGLLKRLKEKKKAKSELGASASRDGPPSALGSRESLATISELDLGAERDVRVWPLHPSLLEEPHCFQVTWAGGSRCFSCRSAAERDRWIEDLRRHFQPSQDNVEREETWLSVWVHEVKGLPRAAAAAPGVRTELWLDGALLARTTPRAGPGQLFWAERFHFEALPPARRLSLRLRGAGPGDAVLGRVALALEELGIPRAPAAGLERWFPLLGAPAGAALRARIRARRLRVLPSERYKELAEFLTFHYARLCGALELALSAQAKEELAAAMVRVLRATGRAQALVTDLGTAELARSGGREALLFRENTLATKAIDEYMKLVAQDYLQETLGQVVRRLCASTEDCEVDPSKCPASDLPQHQSRLRNSCKEVFENIIHSYNWFPAELGTVFSGWREACKARGSEALGPRLVCASLFLRLLCPAILSPSLFGLALEHPAPGPARTLTLIAKVIQNLANRAPFGEKEAYMSFMNTFLEDHGPAMQHFLDQVATVDADTAPSGYQGSSDLALQLAVLHAQLCTIFAELDQATRDNLEPLPTILHAIEEGRPVPVTVPMCLPAPRTQGHSSISAGEKPGFLAPRDLPKHTPLISKSQSLRSVHGAGSWARPRLEEEQPPRLPRPVKRTQSVPAGRPARRRPSAGPRPRPKGSLHAGPAPRGRPWTGASASLPRKPSVPWQRQMDQPRDKDQALGTHRPVGKLAELQCEVAALRQDLKMLSGLVESLSTHIRSLSEQQEQLRTQLQLLDSRLREGTAKLDPGRDRSTNEGHRLKSLECRLAEIESTQAQLKDTIQNLQLLPRTSESQSQPVPLKAPCINGDTT", "length": 1012 }, "evidence": [ { "id": "A0A8C2N099", "url": "https://omabrowser.org/oma/group/A0A8C2N099/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZWW3-1", "protein_name": "RAS protein activator like 3", "gene_name": "Rasal3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPPLQNEDSQTQPSPLTSYRWHTGGRGEKIAGGFRWGRFAGWGRALSHQEPMVSSQPAPRSLFRRVLSAPPKESRPNRLRFSKSLWGRHKNVVPLEPKLNPKAPEPELELEGAPDLRAAHIPEPPAPDMPVWNIDGFALLEGRLVMLGEEEGPRQIRMGSASSESSMQAALGNLKDPVRTPGKIEPEATGSNQVHNVRKLLKRLKEKKRAKSELGAHTPRDGPSSALGSRESLATLSELDLGVERDVRVWPLHPSLLGEPYCFQVTWAGGSRCFSCRSSAERDRWIEDLRRQFQPSQDNVERQETWLTVWVHEAKGLPRAAAPGVRAELWLDGALLARTAPRAGPDQLFWAERFHFEALPPARRLSLRLRGAGPAGATVGRVVLELDEVSIPRAPAAGLERWFPVLGAPAGAVLRARIRVRCLRVLPSERYKELAEFLTFHYARLCMALEPALSAQAKEELAAAMVRVLRATGRAQALVTDLGTAELERCGGREALLFRENTLATKAIDEYMKLVAQEYLQETLGQVVRSLCASTEDCEVDPSKCPTPELPKCQARLRSSCEEVFENIIHSYNYFPAELGTVFSNWREACKARGSEALGPRLVCASLFLRLLCPAILAPSLFGLAPEHPAPGPARTLTLIAKVIQNLANCAPFGEKEAYMVFMNSFLEDHGPAMRHFLDQVAMVDTDTTPSGYQGSGDLALQLAVLHVQLCTIFAELDQKTRDSLEPLPTILQAIEEGRPVPVSVPMRLPLNTAHVQSSFSSGEKPGFLAPRDLPKHTPLISKSQSLRSFQGAGSWARRRPDGERPQRRPRPVLRTQSVPARRPTHHRPAAGSKPRPKGSLRTGPATSGRAWARTSTSLPRKPSVPWQRQLDQPGDRYQTPGTHRPVGKLAEIQCEVAALREEQKALSHLVESLSTHIQALTEQQEQLRCQLQDLDSRLGAGISKLDSKGGLPSNGSLGLKSLEHRMTEMECSQNQLRDTLQSLQLLSKTPGSRSQPPPLKAPCVNGADLSMGT", "length": 1015 }, "evidence": [ { "id": "A0A8C2N099", "url": "https://omabrowser.org/oma/group/A0A8C2N099/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FDZ7-1", "protein_name": "Disabled homolog 2-interacting protein isoform X1", "gene_name": "rasal3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGTNKESNAEQAGAASQIEEDMELVPEQNSPVDQDPRQTEDGKLLNTYKWHTGAKAETVAQGAIERLEKGASNKWNKMQSWRKALSEDPGEKSSTANRGGESPSKPDKPTTSRKNPFRRALSEPPGSLLASSAPASSSAQATGSTVQDTTQRGKIRKYLQTVSQRFKKPRLQSTVTEHEKCEPDYVLQDPVRLSWAPPQEVPVWDISNCFLQDGQILIPREEEPMMTVRNRASSCLFSVSLQNISGSHAELNPDPVVPSSGTKLKGQDGGVKGLIKRRLQGDDKRKSSTQLNTAGLSVAARYGSKESLSIPVSAAKSLNLSADQTTVIRPVHSSILGEKYCFQVINSENNHCFGCTSAAERDRWIEDLRRTAHPNKDNCERTENSLCLWINEAKDLPPKKRYYCEVHLDGTLFARTSSRAVGKSVQRSSQAVDGGSGAFGSGGTSGGCQLFWGEFFELDNLPPVTQITLHLFKGEDPKKKRHSRDDATLHPLGSVALPLADIKGRAYQEKWYRIVAYKPPGTSTAKDSVELQASIRVKAKFKNLKILPIERYKEFAEYVTVNYVDMCSSLEPLLNVREKEELAGALVHVLQSIGKAKEFLIDLGSAEVQRLGENEALIFRENTLATKAIDEYMKLVGQKYLIDTLGDFIARLYNGGENCEVDPLKCSPSDLPINQRHLKETCEDVVKRITDMQESFPAELNDIFSSWVSDCEDRGQQDIGQRLISASLFLRFLCPAILSPSLFGLTQPYPETNTLRTLTLTAKVIQNLANFTLFGEKEEYMFFMNDFLTQHWEPMRDFLQKVSNPESEITMSRFDGYVDLPLRLAVLHNLLVDIISVMKQDQIDNLHPLPRILNQITEFLGHDAQQIPVSSNQAMPKPIYVPPRDLPKYSPLQTSMQQLPIDSKPNQCTKERQRRQVQRAFSVPNRPSRQQRQPMKRQASNEELPTQCPDDNQDHRLEISPPSNPEKSKAAAAAKVHWIKQPDGSETCQVRRQDREETNTLDKHAQELSELRMGVEQVTERELEMAKRLEDFIVLTQDQNAQLQAEVQDLRNLLAIREEQLASATFRLGVIEEEREEDERKLNVAVAAVERMNVLEEQFAGLLKDVHHLYAANSDGLRQTYINT", "length": 1124 }, "evidence": [ { "id": "A0A8C2N099", "url": "https://omabrowser.org/oma/group/A0A8C2N099/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SA02-1", "protein_name": "RAS protein activator like-3", "gene_name": "RASAL3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPPSSSGASQTQPAAPTPLTAYRWHSGGGGEKGAGGFRWGRLAGWGRALSHQETTVSSQPAPRSLFRRVLSAPPKESRTSRLRISKSLWGRHKSPPLESDPEPEAPEPEPEPEPPAPQIPEAPTPDVPVWNIGAFTLLDGRLVLLGGEDESPRRARVGSASSEGSIQAALGNLRDPDRISGKTEPEATGPNQVHNIRGLLKRLKEKKKVKSELGANASRDGPPSALGSRESLATLSELDLGAERDVRVWPLHPSLLEEPHCFQVTWAGGSRCFSCRSAAERDRWIEDLRRHFQPSQDNVEREETWLSVWVHEVKGLPRAAAGSPGVRAELWLDGALLARTTPRTGPGPLFWAERFHFEALPPARRLSLRLRGAGPGCAVLGRVALALEELGVPRAPAAGLERWFPLLGAPAGAALRARIRARRLRVLPSERYKELAEFLTFHYARLCGALELALSAQAKEELAAAMVRVLRATGRAQALVTDLGTAELARSGGREALLFRENTLATKAIDEYMKLVAQDYLQETLGQVVQRLCASMEDCEVDPSKCPASELPQHQARLRNSCKEVFENIIHSYDWFPAELGTVFSGWREACKARGSEALGPRLVCASLFLRLLCPAILSPSLFGLAPEHPAPGPARTLTLIAKVIQNLANCAPFGEKEAYMSFMNSFLEDHGPAMQRFLDQVAMVDVDTAPSGYQGSSDLALQLAVLHAQLCTIFAELDQATRDSLEPLPTILHAIEEGRPVPVSVPMRLPPPPVQVHSSFSAGEKPGFLAPRDLPKHTPLISKSQSLRSVHGAGSWARPRPDEEQAPRLPRPVQRTQSVPAGRPARRRPSSGPRPRPKGSLRTGPTPRGRPWIGASASLPRKPSVPWQRQLDQPRDREQAPGTHRPLSKLAELQCEVAALRQDQKALCGLVESLRTHVRALSEQQELLRSQLQNLDSLIGERTAKLDPELDSPLSEGHRLKSLECRLAEIESTQAQLRDTIQSMQLLPRMSGFGSQPPPLKAPCVNGDTT", "length": 1012 }, "evidence": [ { "id": "A0A8C2N099", "url": "https://omabrowser.org/oma/group/A0A8C2N099/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q86YV0-1", "protein_name": "RAS protein activator like-3", "gene_name": "RASAL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPPSPSRTSQTQPTATSPLTSYRWHTGGGGEKAAGGFRWGRFAGWGRALSHQEPMVSTQPAPRSIFRRVLSAPPKESRTSRLRLSKALWGRHKNPPPEPDPEPEQEAPELEPEPELEPPTPQIPEAPTPNVPVWDIGGFTLLDGKLVLLGGEEEGPRRPRVGSASSEGSIHVAMGNFRDPDRMPGKTEPETAGPNQVHNVRGLLKRLKEKKKARLEPRDGPPSALGSRESLATLSELDLGAERDVRIWPLHPSLLGEPHCFQVTWTGGSRCFSCRSAAERDRWIEDLRRQFQPTQDNVEREETWLSVWVHEAKGLPRAAAGAPGVRAELWLDGALLARTAPRAGPGQLFWAERFHFEALPPARRLSLRLRGLGPGSAVLGRVALALEELDAPRAPAAGLERWFPLLGAPAGAALRARIRARRLRVLPSERYKELAEFLTFHYARLCGALEPALPAQAKEELAAAMVRVLRATGRAQALVTDLGTAELARCGGREALLFRENTLATKAIDEYMKLVAQDYLQETLGQVVRRLCASTEDCEVDPSKCPASELPEHQARLRNSCEEVFETIIHSYDWFPAELGIVFSSWREACKERGSEVLGPRLVCASLFLRLLCPAILAPSLFGLAPDHPAPGPARTLTLIAKVIQNLANRAPFGEKEAYMGFMNSFLEEHGPAMQCFLDQVAMVDVDAAPSGYQGSGDLALQLAVLHAQLCTIFAELDQTTRDTLEPLPTILRAIEEGQPVLVSVPMRLPLPPAQVHSSLSAGEKPGFLAPRDLPKHTPLISKSQSLRSVRRSESWARPRPDEERPLRRPRPVQRTQSVPVRRPARRRQSAGPWPRPKGSLSMGPAPRARPWTRDSASLPRKPSVPWQRQMDQPQDRNQALGTHRPVNKLAELQCEVAALREEQKVLSRLVESLSTQIRALTEQQEQLRGQLQDLDSRLRAGSSEFDSEHNLTSNEGHSLKNLEHRLNEMERTQAQLRDAVQSLQLSPRTRGSWSQPQPLKAPCLNGDTT", "length": 1011 }, "evidence": [ { "id": "A0A8C2N099", "url": "https://omabrowser.org/oma/group/A0A8C2N099/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C2K5-1", "protein_name": "RAS protein activator like-3", "gene_name": "Rasal3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPECGQTMFRTFWSRSRDSSAMDPPLQSEEDSQTQPSLPSPLTSYRWHTGGSGEKAAGGFRWGRFAGWGRALSHQEPMVNSQPAPRSLFRRVLSAPPKESRSNRLRFSKTLWGRHKNVAPLEPKPNPKAPEPELELVADPDLPVAQIPEPPTPDMPVWNIDGFTLLEGKLVMLGEEEGPRQIRVGSASSENSMQAALGNLKDAVRTPGKTEPEAAGSNQVHNVRKLLKRLKEKKRAKSELGAYTPRDGPPSALGSRESLATLSELDLGAERDVRVWPLHPSLLGEPYCFQVTWAGGSLCFSCRSSAERDRWIEDLRRQFQPSQDNVERQEMWLTVWVHEAKGLPRATVPGVRAELWLDGALLARTAPRAGPGQLFWAERFHFEALPPARRLSLRLRSAGPAGATVGRVVLELDEVSIPRAPAAGLERWFPVLGAPAGAVLRARIRVRCLRVLPSERYKELAEFLTFHYARLCGALEPALSAQAKEELAAAMVRVLRATGRAQALVTDLGTAELARCGGREALLFRENTLATKAIDEYMKLVAQEYLQDTLGQVVRCLCASTEDCEVDPSKCPTPELPKHQARLRDSCEEVFENIIHSYNCFPAELGSVFSSWREACKARGSEALGPRLVCASLFLRLLCPAILAPSLFGLAPEHPAPGPARTLTLIAKVIQNLANCAPFGEKEAYMAFMNSFLEDHGPAMQHFLDQVATVDADTTPSGYQGSGDLALQLAVLHVQLCTIFAELDQKTQDSLEPLPTILRAIEEGRPVPVSVPMRLPRISTQVQSSFFSGEKPGFLAPRDLPKHTPLISKSQSLRSFQGAGSWASRRPDEERPQRRPRPVLRTQSVPARRPTHRRPSAGSKPRPKGSLRMGPAPCGRAWTRASASLPRKPSVPWQRQMDQPGDRYQTTGTHRPVGKLAEIQCEVAIFREAQKALSLLVESLSTQVQALKEQQEHFRCQLQDLYSRLGAGISKLDSKGGLPSNGSHRLKSLEQRLTEMECSQDQLRDSLQSLQLLSKTPGSRSQPLPLKAPCVNGADLSMGT", "length": 1041 }, "evidence": [ { "id": "A0A8C2N099", "url": "https://omabrowser.org/oma/group/A0A8C2N099/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of NK T cell proliferation", "id": "GO:0051142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051142", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N099", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099" } ], "pmid": "" }, { "name": "negative regulation of Ras protein signal transduction", "id": "GO:0046580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046580", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N099", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N099", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N099", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N099", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N099", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099" } ], "pmid": "" }, { "name": "cytoplasmic side of membrane", "id": "GO:0098562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098562", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N099", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 711, "end_pos": 713, "annotation": "n_glycosylation_sequon" }, { "start_pos": 979, "end_pos": 981, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 309, "end_pos": 427, "start_aa": "Trp", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N099" }, { "id": "PS50018", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50018" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-GAP", "eco_id": "ECO_0000259", "start_pos": 481, "end_pos": 673, "start_aa": "Ala", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 150, 346 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 711, "end_pos": 713 }, { "start_pos": 979, "end_pos": 981 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N0C1-1", "uniprot_ac": "A0A8C2N0C1", "uniprot_id": "A0A8C2N0C1_CRIGR", "mass": { "chemical_mass": 89884.0, "monoisotopic_mass": 89884.0 }, "refseq": { "ac": "XP_003496338", "name": "AP-5 complex subunit zeta-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496338" }, "gene_names": [ { "name": "Ap5z1", "type": "recommended", "evidence": [ { "id": "A0A8C2N0C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1" } ] }, { "name": "Ap5z1", "type": "synonym", "evidence": [ { "id": "XP_003496338", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496338" } ] } ], "protein_names": [ { "name": "AP-5 complex subunit zeta-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003496338", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496338" }, { "id": "A0A8C2N0C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613618.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003496338", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496338" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0C1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ap5z1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1", "locus": {} } ], "crossref": [ { "id": "100760656", "url": "https://www.ncbi.nlm.nih.gov/gene/100760656", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760656", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760656", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LMLAYEF", "url": "https://omabrowser.org/oma/group/LMLAYEF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N0C1", "url": "https://www.orthodb.org/?gene=A0A8C2N0C1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N3B3", "url": "https://www.orthodb.org/?gene=A0A8C2N3B3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46488", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46488", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46488:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46488:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14764", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14764", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25154", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25154", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003496338", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496338", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N0C1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N3B3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N3B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3B3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXT9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXT9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSAGAESLLHQAREIQDEELQRFCTRVTKLLQEPPGPATMDALQRLFLIVSATKYPRRLEKMCVDLFQTTLCLPTSPEQLQVLCAAILREMSPFDDLALSCDHTQNTRQLSLVASVLLAQGNRKGEIRQVSQRIFKILENRQPEGPSVRHLLPALSKVIGLAPGTLMEDQNNLLSKRLVDWLRYASIQQGLPSSAGFFSTPRTRQPGPITEVDGAVASDFFTVLSTGQHFTEDQWLNMQAFSMLRKWLLHSGPEDPGSPDADDKSELEGSTLSVLSAASTASRLLPPRERLREVAFEYCQRLLEQSNRRALRKADSDLQKACLVEAVLVLDVLCRQDPSFLYRTLSCLKALHRRLGEDPGSERALVPLAQFFLNHGEAAAMDAEVIYQHLLSRLPSERFYSPTLAFEVIHFCTHNLALFDPHILSLLRLSFPSLFKFLAWNSPPLTAEFVVLLPALVEAGTTVEMLHALLDLPCLTAALDLQLRSTQTPSERPLWDVSLRIPGCLEAFRDPQFQGLFRHLLRTKASGSMERLTPLHQLLKPMASCARVTQCAEAVPILLQAFFSTVTQLADGALINQLVLLLLDRSDSLYQAPQYEARVHRVLNSQFLALCKLKPSLVVELSRELLEFVGNVSSICSRASMFTCVVWAIGEYLSVTCDKRCTVEQINKFFEALEALLFEVTQSRPSADLPCCPPQVVTALMTTLTKLASRSQDLIPRVSLFLSKLRTLAQNPATSSVHSEEDAEAIRTRATELLTLLKIPSVAQFVFTPTAGVCQPRYHRDANTALPLALRTVSRLVEKEAGLLPG", "length": 807, "header": "tr|A0A8C2N0C1-1|A0A8C2N0C1_CRIGR Isoform 1 of AP-5 complex subunit zeta-1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ap5z1 PE=4 SV=1 CANONICAL=A0A8C2N0C1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N0C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1/entry#A0A8C2N0C1-1", "sequence": { "sequence": "MFSAGAESLLHQAREIQDEELQRFCTRVTKLLQEPPGPATMDALQRLFLIVSATKYPRRLEKMCVDLFQTTLCLPTSPEQLQVLCAAILREMSPFDDLALSCDHTQNTRQLSLVASVLLAQGNRKGEIRQVSQRIFKILENRQPEGPSVRHLLPALSKVIGLAPGTLMEDQNNLLSKRLVDWLRYASIQQGLPSSAGFFSTPRTRQPGPITEVDGAVASDFFTVLSTGQHFTEDQWLNMQAFSMLRKWLLHSGPEDPGSPDADDKSELEGSTLSVLSAASTASRLLPPRERLREVAFEYCQRLLEQSNRRALRKADSDLQKACLVEAVLVLDVLCRQDPSFLYRTLSCLKALHRRLGEDPGSERALVPLAQFFLNHGEAAAMDAEVIYQHLLSRLPSERFYSPTLAFEVIHFCTHNLALFDPHILSLLRLSFPSLFKFLAWNSPPLTAEFVVLLPALVEAGTTVEMLHALLDLPCLTAALDLQLRSTQTPSERPLWDVSLRIPGCLEAFRDPQFQGLFRHLLRTKASGSMERLTPLHQLLKPMASCARVTQCAEAVPILLQAFFSTVTQLADGALINQLVLLLLDRSDSLYQAPQYEARVHRVLNSQFLALCKLKPSLVVELSRELLEFVGNVSSICSRASMFTCVVWAIGEYLSVTCDKRCTVEQINKFFEALEALLFEVTQSRPSADLPCCPPQVVTALMTTLTKLASRSQDLIPRVSLFLSKLRTLAQNPATSSVHSEEDAEAIRTRATELLTLLKIPSVAQFVFTPTAGVCQPRYHRDANTALPLALRTVSRLVEKEAGLLPG", "length": 807, "header": "tr|A0A8C2N0C1-1|A0A8C2N0C1_CRIGR Isoform 1 of AP-5 complex subunit zeta-1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ap5z1 PE=4 SV=1 CANONICAL=A0A8C2N0C1-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N3B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1/entry#A0A8C2N3B3-1", "sequence": { "sequence": "MDALQRLFLIVSATKYPRRLEKMCVDLFQTTLCLPTSPEQLQVLCAAILREMSPFDDLALSCDHTQNTRQLSLVASVLLAQGNRKGEIRQVSQRIFKILENRQPEGPSVRHLLPALSKVIGLAPGTLMEDQNNLLSKRLVDWLRYASIQQGLPSSAGFFSTPRTRQPGPITEVDGAVASDFFTVLSTGQHFTEDQWLNMQAFSMLRKWLLHSGPEDPGSPDADDKSELEGSTLSVLSAASTASRLLPPRERLREVAFEYCQRLLEQSNRRALRKADSDLQKACLVEAVLVLDVLCRQDPSFLYRTLSCLKALHRRLGEDPGSERALVPLAQFFLNHGEAAAMDAEVIYQHLLSRLPSERFYSPTLAFEVIHFCTHNLALFDPHILSLLRLSFPSLFKFLAWNSPPLTAEFVVLLPALVEAGTTVEMLHALLDLPCLTAALDLQLRSTQTPSERPLWDVSLRIPGCLEAFRDPQFQGLFRHLLRTKASGSMERLTPLHQLLKPMASCARVTQCAEAVPILLQAFFSTVTQLADGALINQLVLLLLDRSDSLYQAPQYEARVHRVLNSQFLALCKLKPSLVVELSRELLEFVGNVSSICSRASMFTCVVWAIGEYLSVTCDKRCTVEQINKFFEALEALLFEVTQSRPSADLPCCPPQVVTALMTTLTKLASRSQDLIPRVSLFLSKLRTLAQNPATSSVHSEEDAEAIRTRATELLTLLKIPSVAQFVFTPTAGVCQPRYHRDANTALPLALRTVSRLVEKEAGLLPG", "length": 767, "header": "tr|A0A8C2N3B3-1|A0A8C2N0C1_CRIGR Computationally mapped isoform of AP-5 complex subunit zeta-1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ap5z1 PE=4 SV=1 CANONICAL=A0A8C2N0C1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FXT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1/entry#A0A9J7FXT9-1", "sequence": { "sequence": "MFSAGAESLLHQAREIQDEELQRFCTRVTKLLQEPPGPATMDALQRLFLIVSATKYPRSPEQLQVLCAAILREMSPFDDLALSCDHTQNTRQLSLVASVLLAQGNRKGEIRQVSQRIFKILENRQPEGPSVRHLLPALSKVIGLAPGTLMEDQNNLLSKRLVDWLRYASIQQGLPSSAGFFSTPRTRQPGPITEVDGAVASDFFTVLSTGQHFTEDQWLNMQAFSMLRKWLLHSGPEDPGSPDADDKSELEGSTLSVLSAASTASRLLPPRERLREVAFEYCQRLLEQSNRRALRKADSDLQKACLVEAVLVLDVLCRQDPSFLYRTLSCLKALHRRLGEDPGSERALVPLAQFFLNHGEAAAMDAEVIYQHLLSRLPSERFYSPTLAFEVIHFCTHNLALFDPHILSLLRLSFPSLFKFLAWNSPPLTAEFVVLLPALVEAGTTVEMLHALLDLPCLTAALDLQLRSTQTPSERPLWDVSLRIPGCLEAFRDPQFQGLFRHLLRTKASGSMERLTPLHQLLKPMASCARVTQCAEAVPILLQAFFSTVTQLADGALINQLVLLLLDRSDSLYQAPQYEARVHRVLNSQFLALCKLKPSLVVELSRELLEFVGNVSSICSRASMFTCVVWAIGEYLSVTCDKRCTVEQINKFFEALEALLFEVTQSRPSADLPCCPPQVVTALMTTLTKLASRSQDLIPRVSLFLSKLRTLAQNPATSSVHSEEDAEAIRTRATELLTLLKIPSVAQFVFTPTAGVCQPRYHRDANTALPLALRTVSRLVEKEAGLLPG", "length": 789, "header": "tr|A0A9J7FXT9-1|A0A8C2N0C1_CRIGR Computationally mapped isoform of AP-5 complex subunit zeta-1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ap5z1 PE=4 SV=1 CANONICAL=A0A8C2N0C1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3B3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3B3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3B3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3B3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760656", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760656", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JYJ5-1", "protein_name": "Adaptor related protein complex 5 subunit zeta 1", "gene_name": "Ap5z1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSAGAESLLHQAREIQDEELQRFCSRVTKLLQEAPGPATVDALQRLFLIVSSTKYPRRLEKACVDLLQTTLCLPTSPEQLQVLCAAILREMSPFNDLTLSCDHTQNTRQLSLVASVLLAQGDRNGEIRQVSQRIFKILENRQPEGPSVRPLLPVLSKVIGLAPGILVEDQTNLLSKRLVDWLRYASIQQGLPYSGGFFSTPRTRQPGPITEVDGAVASDFFTVLSTGQHFTEDQWVNMQAFSMLRKWLLHSGPEDPGSPDADDKSELEGSMLSVLSAASTASRLLPPRERLREVAFEYCQRLLEQSNRRALRKGDSDLQKACLVEAVLVLDVLCRQDPSFLYRTLSCLKPLHRRLGEDPGSERALVPLAQFFLNHGEAAAMDAEAIYAQLLGSLPSERFHSPTLAFEVIHFCTHNLALFDPHFLSLLRLSFPNLFKFLAWNSPPLTAEFVVLLPALVDAGTAVEMLHALLDLPCLTAALDLQLRSTQTPSERPLWDVSLRVPSCLEAFQDPQFQGLFRHLLRTKASGSTERLTPLHQVLKPMASCARVAQCVEAIPVLLQAFFSAVTQTADGPLINQLALLLLERSDSLYPVPQYEARVHRVLSSQLLVLCKLKPSLVVELSRELLEFVGSVSSIRSRASMFTCVVWAIGEYLSVTCDKRCTAEQINKFFEALEALLFEVTQSRPSADLPCCPPELVTALMTTLTKLASRSQDLIPRVSLFLSKMRTLAQNPATSSMHSEEDTESIRIRATELLTLLKMPSVAQFVFTPTVGVCQPRYHQDTNVALPLALRTVSRLVEKEAGLLPG", "length": 807 }, "evidence": [ { "id": "A0A8C2N0C1", "url": "https://omabrowser.org/oma/group/A0A8C2N0C1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M6YX82-1", "protein_name": "AP-5 complex subunit zeta-1 isoform X1", "gene_name": "ap5z1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYAAATESLIKQAREIKEEELQRFCGRVYKLLHSKDVIGEAVDSLQRLHLIVSATKYARELPSDLLMKLQTLLRSSSCPEQLQFLSSSIIRESFPPSVHSLSSDLSQDSRIFSCVAAVVLAQAGGKEDVMPLFHHLMKSFESRLSDGQIPKHALPILSSMITTYSEILTDDQVNLVSRKLVDWLRYASMQQGASMSSGGFFSAPRTRQPAPLTEVDGVVTGDFFTVLCVGQSYTEDQWMNMYAFSMIKSWLLTYDTEGTTNTESALLKRAQIIQLQHQDDRSEVDSSVMSMVSATSSSSRLLPPKERLREKAFEYCQRLIEQSDRKALKRTDTELQKACIVESVSIMDIICGEDPSYVYRAFPCIKALYGRLNGDFAYARTLLPIAQFYLNHSETAAVDSEAVFCQLFGHCPAEQFNEPMLAFEFVQFCLLNSSVLQDRVANYRQSFPNLLKFLAWNSSGLIAEFVELLPSLVAPDTAIELLHTILDLPCLAAALDLQQRSSCYQASDRTTWDQQGAKVAACLEAFRQPSYRGLFLYILRPEAGTGDTIDRLKELHQILADMAECPRVVQCAQIVPVLLHVYFNTVTEKADEKMMNQLLLVLLERCSLLYNIKTFHVEVQRAFSTHLQALCKHHPPLIVDQSREILEFAGSPTNIYSKEDFYTHVVWVIGEYLSVSYDPRCRVELITSFFECLEAVLFEITQVRQSASPPSFSPRLITVLMTTLAKLATRSQDLIPRASLFLSKMRTFARSAPVTACYSEEDTEEIITRAHELINLLKLPNVAQFVLAPSAGADGPRWHRDTNASLPQAMRTVSGLLHKHSSFLPA", "length": 826 }, "evidence": [ { "id": "A0A8C2N0C1", "url": "https://omabrowser.org/oma/group/A0A8C2N0C1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0ZI01-1", "protein_name": "Adaptor related protein complex 5 subunit zeta 1", "gene_name": "AP5Z1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGTAAAESLLKQAREVQEDELSRFAARVAAQLQGPEPGPEAADCLQRLHLVLAASKSPRQLDAQLVELLQAVLCSPKCPQQIQLLCAAILREMAPCDGLRLSCERIHDTKLLSLVSSVLLAQGEEKAEVSAVGQRIVKALEGRLPEGQSSRYLLPVLSNVISLSPEALTEEQTNVVSKKMADWLRYASTQQGVAQPSGGFFSNPRTRQPGPVTEVDGAIATDFFTVLSLGQHYTEDQWLNMQTFSMLRKWLLCYGDKKMNTPNSGDKSQTDRSVVSVVSTSSTSSRLLPPKERLREKAFEYCQRLIEQSNRQALKKADGDLQKACLIEAVAIMDIICKQDSSYVYRAASFLKILHGRISGDATYARALLPIAQFFLNHGEMAAVDSDAIYKHLFTDIPAQLFHNSSLAFEFVLFCRDNSQLLTETSSVFRQSFPNLFKFLAWNSPPLIAEFVDILPFLLDAGTAIEIFHLLLDLPCLTAALDVQMRSSSLPSSERAACDPAVKPAACLEAFRSPLYRSAFQYLLRVESVSEDFQERLIPLRQLLGSLASSPRVVQCADTVPVLLELFFSVVSEFADASLINQLVVLVLQRSDQLYEIPAFKDDVHRVLSSQLVMLCKLHPALIVELSKELLEFSGTVSNIQNKEPIFTHVVWAIGEYMSVSYDKRCTVEQINRFFETLEAVLFEVTQVRPQISVPNYAPRAITVLMAALTKLAARSQDLIPRVSLFLSKMRTFVQSPAVTSVYCEEDREEILTRATELMNLLKMPSVAQFVFTPSVDVARTRFQKEVNDTLPSALRIVTRLLEPAPGFVPG", "length": 811 }, "evidence": [ { "id": "A0A8C2N0C1", "url": "https://omabrowser.org/oma/group/A0A8C2N0C1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9TCS9-1", "protein_name": "Adaptor related protein complex 5 subunit zeta 1", "gene_name": "AP5Z1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRHAARPGSRRRCGHCFASRPCLERAARPQGGGGGGMLATGTESLLRQAREVGAEELGRFCARVSALLQAEDWGPDALDALRRLFLIVAATKYSRRLEPTCVALLQTTLCSPRCPERLQLLCAAVLREMAPSDSLSLSCDHAQSSRQLGLVASVLLAQGDPQQVRTVGQCVIKVLESRQPEGPSLTYLLPVVSKVTSLAPDALPEEQTKALSKRLGEWLRYASVQQGAAHASGGFFSTPRARQPGPVTEVDGTVATDFFTVLSTGQRFTEDQRLNVQAFSMLRAWLLQGGPARPGAADADDRSELEGSTVSVLSAASAASHLLPPAEWLREKALEYCQRLLEQSGRRALRKADSDLQKACLVEAVLVLDVLCRQDPSFLYRALPCVRALRTRLCGDTACVRALLPIAQFFLHHGEAAAVDADAVCQHLFTRIPSEHFHSPMLAFEFVQFCRDHLVLFGSNLDLLRTSFPNLFKFLAWSSPALTSGFVALLPVLVDAGTAVEMLHLLLDLPSLTAALDLQLRASQAASERPLWDVSVRAPGCLEALRDPQAQGLFQHLLRAKASGTVERLTPLHQLLQPLASCARVLQCAQAVPTLLRAFFAAVTQFASGALASQLALLLLERSDSLFQVEGYEADVHRVLSSQFPALCKLHPPLVVERAKELLEFVGSLGGPRSTGHMLTSVVWAVGEYLSVSWDRRCSAEQISRFFEALEALLFEVTQSRPSAALPKCPPQVITVLMTTLTKLASRSQDLIPRVSLLLSKMRTLAQSPAVGPVHGEDDLGAVRTRATELLNLLKMPSVAQFVLTPSVEVSQPRYHRDCNTALPLALDMVSRLLEREAGLLPGTRPPQHLPLEAVPGRSRALCSSPE", "length": 867 }, "evidence": [ { "id": "A0A8C2N0C1", "url": "https://omabrowser.org/oma/group/A0A8C2N0C1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RI49-1", "protein_name": "Adaptor related protein complex 5 subunit zeta 1", "gene_name": "AP5Z1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTAGAESLLRQAREIRDEELGRLCSRVCALLGREDWGPDALDALRRLFLIVSATKHGRRLEQPCVELLQAALCSPTCPEQLQLLCAAVLREVSPSRSLSLTCDRVQNTQQLGLVASVLLAQGDRRQVGSVGQCALRVLESRQPEGPGLRHLLPVVSKVTNLAPDALHEEQTNTLNRRLGDWLRHASVQQGIAHSSGGFFSTPRARQPGPVTEVDGAVATDFFTVLSTGQHFTEDQWLNVQAFSMLRAWLLHGGPGGSSTPDADDRSELEGSTLSVLSAASTASHLLPPQERLREKAFEYCQRLIEQSNRRALRKADSELQKACLVEAVLVLDVLCRQDPSFLYRTLSCLRALHARLCGDPTCVRALLPVAQFFLHHGEAAAVDAEAVYQHLCTRIPAEHFHSPLLALEFVQFCRASLPLFGRHLGVLRSSFPNLFKFLAWSSPPLTAEFVALLPSLVDAGTAVEMLDLLLDLPCLTAALDLQLRSSQAASEKPLWDVSVRAAGCLEAFRDPQYQALFQHLLRAKASGTTERLVPLHQLLQPLAGCARVAQCAEAVPILLQAFFAAVTQFADGTLTSQLALLLLERSDTLYEVPGYQARVHKVLSSQFLALCTRRPSLVVEQAKELLEFVGSLGGPHGGGHMLTSVVWAIGEYLSVSWDRRCTVEQINKFFEALEALLFEVTQSRPSAALPACPPQVITVLMTTLTKLASRSQDLIPRVSLFLSKMRTLAQSPAAGSAHGEEDARAVLTRATELLNLLKMPSVAQFVLTPSAEVSEPRYHRDTNTALPLALSTVSRLVERDAGLLPG", "length": 807 }, "evidence": [ { "id": "A0A8C2N0C1", "url": "https://omabrowser.org/oma/group/A0A8C2N0C1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O43299-1", "protein_name": "AP-5 complex subunit zeta-1", "gene_name": "AP5Z1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSAGAESLLHQAREIQDEELKKFCSRICKLLQAEDLGPDTLDSLQRLFLIISATKYSRRLEKTCVDLLQATLGLPACPEQLQVLCAAILREMSPSDSLSLAWDHTQNSRQLSLVASVLLAQGDRNEEVRAVGQGVLRALESRQPEGPSLRHLLPVMAKVVVLSPGTLQEDQATLLSKRLVDWLRYASLQQGLPHSGGFFSTPRARQPGPVTEVDGAVATDFFTVLSSGHRFTDDQWLNVQAFSMLRAWLLHSGPEGPGTLDTDDRSEQEGSTLSVISATSSAGRLLPPRERLREVAFEYCQRLIEQSNRRALRKGDSDLQKACLVEAVLVLDVLCRQDPSFLYRSLSCLKALHGRVRGDPASVRVLLPLAHFFLSHGEAAAVDSEAVYQHLFTRIPVEQFHSPMLAFEFIQFCRDNLHLFSGHLSTLRLSFPNLFKFLAWNSPPLTSEFVALLPALVDAGTALEMLHALLDLPCLTAVLDLQLRSAPAASERPLWDTSLRAPSCLEAFRDPQFQGLFQYLLRPKASGATERLAPLHQLLQPMAGCARVAQCAQAVPTLLQAFFSAVTQVADGSLINQLALLLLGRSDSLYPAPGYAAGVHSVLSSQFLALCTLKPSLVVELARDLLEFLGSVNGLCSRASLVTSVVWAIGEYLSVTYDRRCTVEQINKFFEALEALLFEVTQCRPSAALPRCPPQVVTVLMTTLTKLASRSQDLIPRASLLLSKMRTLAHSPATSSTHSEEGAEAIRTRATELLTLLKMPSVAQFVLTPSTEVCSPRYHRDANTALPLALRTVSRLVEREAGLMPG", "length": 807 }, "evidence": [ { "id": "A0A8C2N0C1", "url": "https://omabrowser.org/oma/group/A0A8C2N0C1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3U829-1", "protein_name": "AP-5 complex subunit zeta-1", "gene_name": "Ap5z1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSAGAESLLHQAREIQDEELRRFCSRVTKLLQEAPGPATVDALQRLFLIVSATKYPRRLEKMCVDLLQTTLCLPASPEQLQVLCAAILREMSPFNDLALSCDHTPNTRQLSLVASVLLAQGDRKGEIRCVSQRIFKILENRQPEGPSVRPLLPILSKVIGLAPGILMEDQTNLLSKRLVDWLRYASIQQGLPYSGGFFSTPRTRQPGPITEVDGAVASDFFTVLSTGQHFTEDQWVNMQAFSMLRKWLLHSGPEDPCSPDADDKSELEGSTLSVLSAASTASRLLPPRERLREVAFEYCQRLLEQSNRRALRKGDSDLQKACLVEAVSVLDVLCRQDPSFLYRTLSCLKALHRRLGEDPGSERALVPLAQFFLNHGEAAAMDAEAVYGQLLRGLPSERFHSPTLAFEVIHFCTHNLALFDSHFLSLLRLSFPSLFKFLAWNSPPLTAEFVVLLPALVDAGTAVEMLHALLDLPCLTAALDLQLRSTQTPSERLLWDISLRVPSCLEAFQDPQFQGLFRHLLRTKASGSTERLTPLHQVLKPMASCARVTQCAEAVPVLLQAFFSAVTQTADGALINQLALLLLERSDSLYPVPQYEARVHGVLSSQLLVLCKLKPSLVVELSRELLEFVGSVSSIHSRASVFTCVVWAIGEYLSVTWDKRCTAEQINKFFEALEALLFEVTQSRPLADLPCCPPEVVTALMTTLTKLASRSQDLIPRVSLFLSKMRTLAQNPATSSVHSEEGAESIRTRASELLTLLKMPSVAQFVFTPPAGVCQPRYHRDTNVALPLALRTVSRLVEKEAGLLPG", "length": 807 }, "evidence": [ { "id": "A0A8C2N0C1", "url": "https://omabrowser.org/oma/group/A0A8C2N0C1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B09-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MQTNVSGAVNIEELLNKIENVFGKNQKSLSINSTFIEKFTTLLLDPNTPYKIKLFTLSTLSKFSKNEHQILYKNFKTFDPKTLPLILSLLLSTGTDSQIYISSIPFLVQTISSQDPITRSASMPSLAISARYHSNSLTNLHIKPIETQLIQFLSHASLISDQKQSSIGFFSKIGNTSATPVTELDGSVSIEFFTVLNNSTNYTEDQTFNIYSFSILYTWLINLYKINKQQSLTNTDQQIEQLDQQIEQQLELIEKQQDQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHRTLNQSFQNTIVSYCLRLIDQSKLKPIDGSGNNNSNLNGGNSGNSNSSGGGSMIYNKPIQQQSATAIALGIDESGGDDLSVMALLESIRILDYLCLLDSNLIAKIFPTVQKAYQLHLPSSKNTNATSGHILLALLQFFVNHSHTLVYDPEPLFKVYFQTYLPRTYMNSFVSFETINFCLKNKKTLLKNSNVFNLYFPPIFKCLAWFPNSLSGEFSELLPSFISPNSFIEVFHLLLDLPLLTLSMESVLVEQRKYASMGIEHNDVGVDTAWSEYRVLYNYLLRNESGVNINFWSTTTLPLLQQFCKKNPVTPRSIGSCELVPLLLDIYFEVLLEYGSLNTFVTLLPVIFERMEQIFPYEPYQKRIRENLMSHLLSIFKKHSTLIQSEKELILSVISEARMTYKDIVTLSLSFIIGEYCSPYVCPTITSDVYSDYHEALELITYEKINTIKMESLSNSSQSSLQQSSLIMKQQQQQQQKQQQHQQEQSSSSNNNNNDIKNIENNENDNDIEKLNNDKKNNDNENDQNQNFINNYNLNYNLNINILNNINNFNLNNIIDNDDFEKLQEQYNINIMLNLISSLTKIASRWPDATSRVVLCLMKIIGYQQYFDPQVIQRANESISLLKYPSFAAALYSCQQPQNDSFHSTISSTTIGQTIQDCNSSLSFLLNDTLNYKSKNTIHPFILK", "length": 975 }, "evidence": [ { "id": "A0A8C2N0C1", "url": "https://omabrowser.org/oma/group/A0A8C2N0C1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0C1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0C1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1" } ], "pmid": "" }, { "name": "AP-5 adaptor complex", "id": "GO:0044599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044599", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0C1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0C1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0C1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 632, "end_pos": 634, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N0C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1" }, { "id": "PF14764", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14764" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP-5 complex subunit zeta-1 ARM repeats", "eco_id": "ECO_0000259", "start_pos": 319, "end_pos": 437, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N0C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1" }, { "id": "PF25154", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25154" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP-5 complex subunit zeta-1 C-terminal TPR", "eco_id": "ECO_0000259", "start_pos": 449, "end_pos": 797, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N0C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0C1" }, { "id": "PF25153", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25153" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP-5 complex subunit zeta-1 N-terminal TPR", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 278, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 632, "end_pos": 634 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N0E8-1", "uniprot_ac": "A0A8C2N0E8", "uniprot_id": "A0A8C2N0E8_CRIGR", "mass": { "chemical_mass": 46173.0, "monoisotopic_mass": 46173.0 }, "refseq": { "ac": "XP_027249070", "name": "ubiquitin-conjugating enzyme E2 Q1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249070" }, "gene_names": [ { "name": "Ube2q1", "type": "recommended", "evidence": [ { "id": "A0A8C2N0E8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0E8" } ] }, { "name": "Ube2q1", "type": "synonym", "evidence": [ { "id": "XP_027249070", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249070" } ] } ], "protein_names": [ { "name": "E2 ubiquitin-conjugating enzyme", "type": "recommended", "evidence": [ { "id": "A0A8C2N0E8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0E8/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.23", "type": "synonym", "evidence": [ { "id": "A0A8C2N0E8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0E8/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-conjugating enzyme E2 Q1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027249070", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249070" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027249070", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249070" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0E8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0E8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ube2q1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0E8", "locus": {} } ], "crossref": [ { "id": "cd23802", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23802", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100750390", "url": "https://www.ncbi.nlm.nih.gov/gene/100750390", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750390", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750390", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VFPKNHE", "url": "https://omabrowser.org/oma/group/VFPKNHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N0E8", "url": "https://www.orthodb.org/?gene=A0A8C2N0E8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF00179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027249070", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249070", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N0E8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0E8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0E8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0E8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8S9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7V7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7V7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQQPQPQGQQQPGPGQQLGVQGAAPGAGGGPGGGPGPGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPSRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEEVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG", "length": 422, "header": "tr|A0A8C2N0E8-1|A0A8C2N0E8_CRIGR Isoform 1 of E2 ubiquitin-conjugating enzyme OS=Cricetulus griseus OX=10029 GN=Ube2q1 PE=4 SV=1 CANONICAL=A0A8C2N0E8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N0E8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0E8/entry#A0A8C2N0E8-1", "sequence": { "sequence": "MQQPQPQGQQQPGPGQQLGVQGAAPGAGGGPGGGPGPGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPSRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEEVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG", "length": 422, "header": "tr|A0A8C2N0E8-1|A0A8C2N0E8_CRIGR Isoform 1 of E2 ubiquitin-conjugating enzyme OS=Cricetulus griseus OX=10029 GN=Ube2q1 PE=4 SV=1 CANONICAL=A0A8C2N0E8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H8S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0E8/entry#A0A9J7H8S9-1", "sequence": { "sequence": "MQQPQPQGQQQPGPGQQLGVQGAAPGAGGGPGGGPGPGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPSRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEEVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQA", "length": 359, "header": "tr|A0A9J7H8S9-1|A0A9J7H8S9_CRIGR Computationally mapped isoform of Ubiquitin-conjugating enzyme E2 Q1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Ube2q1 PE=4 SV=1 CANONICAL=A0A8C2N0E8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J7V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0E8/entry#A0A9J7J7V7-1", "sequence": { "sequence": "MLDQPLPAEQCTQEEVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG", "length": 253, "header": "tr|A0A9J7J7V7-1|A0A9J7J7V7_CRIGR Computationally mapped isoform of E2 ubiquitin-conjugating enzyme OS=Cricetulus griseus OX=10029 GN=Ube2q1 PE=4 SV=1 CANONICAL=A0A8C2N0E8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0E8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0E8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0E8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0E8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750390", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750390", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NVE2-1", "protein_name": "E2 ubiquitin-conjugating enzyme", "gene_name": "UBE2Q1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQRAGAEEAAGSQAAAGGAGRSGAGLAAAPAGRLLKRELRLLESIFHRGHERFRIGSACPDEISCEFVPGAGARAGGSASRGPPPGPVRIHCNITESYPAVPPIWSVESDDPNLAAILERLVEVRKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQSTQEEVSSEEEDEEMPEDTEDLDHYEMKEEEPADGRKTEDEGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSPSFKGGYYAVELVNDSLYDWNVKLLKVDEDSALHNDLQILKEKEGTDFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKNQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG", "length": 408 }, "evidence": [ { "id": "A0A8C2N0E8", "url": "https://omabrowser.org/oma/group/A0A8C2N0E8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B2GV55-1", "protein_name": "E2 ubiquitin-conjugating enzyme", "gene_name": "Ube2q1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQQPQPQGQQQPGPGQQLGVQGAAPGAGGGPGGGPGPGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPSRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEEVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG", "length": 422 }, "evidence": [ { "id": "A0A8C2N0E8", "url": "https://omabrowser.org/oma/group/A0A8C2N0E8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TSS2-1", "protein_name": "Ubiquitin-conjugating enzyme E2 Q1", "gene_name": "Ube2q1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQQPQPQGQQQPGPGQQLGVQGAAPGAGGGPGGGPGPGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPSRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEEVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG", "length": 422 }, "evidence": [ { "id": "A0A8C2N0E8", "url": "https://omabrowser.org/oma/group/A0A8C2N0E8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z7E8-1", "protein_name": "Ubiquitin-conjugating enzyme E2 Q1", "gene_name": "UBE2Q1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQPQPQGQQQPGPGQQLGGQGAAPGAGGGPGGGPGPGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPPRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEDVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG", "length": 422 }, "evidence": [ { "id": "A0A8C2N0E8", "url": "https://omabrowser.org/oma/group/A0A8C2N0E8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0E8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0E8" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0E8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0E8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0E8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0E8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N0E8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0E8" }, { "id": "PS50127", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50127" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBC core", "eco_id": "ECO_0000259", "start_pos": 251, "end_pos": 415, "start_aa": "Gln", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.23", "ec_name": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "2.3.2.23", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.23" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 280, "end_pos": 282 }, { "start_pos": 318, "end_pos": 320 }, { "start_pos": 389, "end_pos": 391 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N0G5-1", "uniprot_ac": "A0A8C2N0G5", "uniprot_id": "A0A8C2N0G5_CRIGR", "mass": { "chemical_mass": 25902.0, "monoisotopic_mass": 25902.0 }, "refseq": { "ac": "XP_027273958", "name": "protein-lysine methyltransferase METTL21D", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273958" }, "gene_names": [ { "name": "Vcpkmt", "type": "recommended", "evidence": [ { "id": "A0A8C2N0G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5" } ] }, { "name": "Vcpkmt", "type": "synonym", "evidence": [ { "id": "XP_027273958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273958" } ] } ], "protein_names": [ { "name": "Protein N-lysine methyltransferase METTL21D", "type": "recommended", "evidence": [ { "id": "A0A8C2N0G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5/entry#names_and_taxonomy" } ] }, { "name": "Methyltransferase-like protein 21D", "type": "synonym", "evidence": [ { "id": "A0A8C2N0G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5/entry#names_and_taxonomy" } ] }, { "name": "VCP lysine methyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8C2N0G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5/entry#names_and_taxonomy" } ] }, { "name": "Valosin-containing protein lysine methyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8C2N0G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5/entry#names_and_taxonomy" } ] }, { "name": "protein-lysine methyltransferase METTL21D", "type": "synonym", "evidence": [ { "id": "XP_027273958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273958" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273958", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273958" } ] }, { "annotation": "Protein N-lysine methyltransferase that specifically trimethylates 'Lys-315' of VCP/p97; this modification may decrease VCP ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0G5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5#function" }, { "database": "UniProtKB", "id": "ARBA00053926", "url": "https://www.uniprot.org/uniprotkb/ARBA00053926#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0G5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Vcpkmt", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5", "locus": {} } ], "crossref": [ { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769613", "url": "https://www.ncbi.nlm.nih.gov/gene/100769613", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769613", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769613", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N0G5", "url": "https://www.orthodb.org/?gene=A0A8C2N0G5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14614:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14614:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273958", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273958", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "54192", "url": "https://www.rhea-db.org/rhea/54192", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N0G5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATAVEPASEPEAEDPLWSFVRVLEKRDGTALRLQQYGSGGVGCVVWDAAIVLSKYLETPAFSGDGAHALSRRSVLELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKWGEELEDLTSPDYILMADCIYYEESLEPLLKTLKELSGSETCIICCYEQRTMGKNPEIEKKYFELLQLDFDFEEIPLDKHDEEYRSEDIRIIYIKKKKSKLPS", "length": 232, "header": "tr|A0A8C2N0G5-1|A0A8C2N0G5_CRIGR Isoform 1 of Protein N-lysine methyltransferase METTL21D OS=Cricetulus griseus OX=10029 GN=Vcpkmt PE=3 SV=1 CANONICAL=A0A8C2N0G5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N0G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5/entry#A0A8C2N0G5-1", "sequence": { "sequence": "MATAVEPASEPEAEDPLWSFVRVLEKRDGTALRLQQYGSGGVGCVVWDAAIVLSKYLETPAFSGDGAHALSRRSVLELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKWGEELEDLTSPDYILMADCIYYEESLEPLLKTLKELSGSETCIICCYEQRTMGKNPEIEKKYFELLQLDFDFEEIPLDKHDEEYRSEDIRIIYIKKKKSKLPS", "length": 232, "header": "tr|A0A8C2N0G5-1|A0A8C2N0G5_CRIGR Isoform 1 of Protein N-lysine methyltransferase METTL21D OS=Cricetulus griseus OX=10029 GN=Vcpkmt PE=3 SV=1 CANONICAL=A0A8C2N0G5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0G5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0G5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769613", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769613", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0G5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0G5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0G5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5" } ], "pmid": "" }, { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0G5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0G5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0G5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], 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"A0A8C2QKF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QKF0" } ] } ] }, { "uniprot_ac": "A0A9J7FX75", "gene_name": "Setd2", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A9J7FX75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX75" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "A0A9J7FX75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX75" } ] } ] }, { "uniprot_ac": "G3HVD6", "gene_name": "Eef1akmt2", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "G3HVD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVD6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], 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predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613630.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027240154", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240154" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mtus2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H1", "locus": {} } ], "crossref": [ { "id": "100755920", "url": "https://www.ncbi.nlm.nih.gov/gene/100755920", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051293", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051293", "database": "InterPro", "categories": [ "Protein Classification" ] 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"https://www.ncbi.nlm.nih.gov/protein/XP_027240154", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N0H1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSIPLAPKKHCFSQLREHQDRAKNNNESILSMGDTNANQIMLEVSSPNDEPRTRDLDDEIGNANVSRPQYHSHSQKQPPQPQGFGKGAQAASTSQRDFHPSLVVHRQPSEEHTVKRAILQTPQSVQGPGLASWRNAVGQASLEGSAKRDAEVPRHIPKDKLAKTLDNEELKRASSSAASAGSLIWENLQPMRLDTSEPQGLVPGRGEGPQGTLAGHTPGTVLSVGEGTSAGRCVCPPKPSTSEARGSIPSVTKMEGTHGLDLYSECIPHPESTPNSASALMEIPSPSHPEVFVGQGTGELKVERKYLQPRNEQGLKSSQAQGLGCHEEKSMSPVERKELHEKTHQEATSQLNSSHHQLKVGEGSGLEEMMGVSAGVEGFQQATPAQSTAPGEGGTRLTGKTSPGALGRTMRETASSDFAPSDGHIACVLRDTESISSEVSREERSQGSQNGGSAKALAAGPSVGGNRAEAPELLGPHSGNSEARKGRETATPVAEDRNRLENAAQTEVAPAGGDSVFSTSAPLHPETTVNLTHHPTPQGSSSQFSVDTGSTLVALPPTDGGQVLNTSLKVPDKSTCPSGIPKPLSHPKDAPSSQEATEKLEMEKVEERTETKPVLMPKPKHVRPKIITYIRRNPQALGQGDASLVPVGLPYAPPSCGMPLPQEEKTANRDLQPSANMYEKFKPDLQKPRVFPSGLMVSGIKPPGHHFSQMSEKFLQEVTDHPGKEEFCSPPYTHYEVPPTFYRSAMLLKPQLGLGAMSRLPSTKSRILIASQRSSASAIHPPGPITTAASFYGSDPSDLKKTSNSNAAKSSLPKSGLRPPGYSRLPAAKLAAFGFVRSSSVSAVPSTQSMDTVQPEQSRPATRSAFGNEEQPPLKPAPPSKDTPKGTGRAAPTPSSNAATPRRSLLPAPKSTSMPAGTKKEAQKDPDANKPAVSSPKRTAASSTKLHSPGYPKQRTTASRNGITPKPDLQAREAERQLAQRLRDRCEWQARQLGLARGELKKAIRGFDALAVSTQHFFGKSESALSKEKELSIELANIRDEVAFNTAKCEKLQKEKEALERRFEEELRRLGWQQQAEVQELQERLQQQFQAESAHLQAEHQDQLLRMRCQHQEQVEDITASHEAALLEMENNHTVAITILQDDHDHKVQELMATHEFEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRAQRFEEALRKTTEEQLEIALAPYQHLEEDMQSLKQVLEMKNQQIHLQEKKIIELEKLVEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSPVYRGSSSGPSSPARVSTTPR", "length": 1350, "header": "tr|A0A8C2N0H1-1|A0A8C2N0H1_CRIGR Isoform 1 of Microtubule-associated tumor suppressor candidate 2 OS=Cricetulus griseus OX=10029 GN=Mtus2 PE=4 SV=1 CANONICAL=A0A8C2N0H1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N0H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H1/entry#A0A8C2N0H1-1", "sequence": { "sequence": "MSIPLAPKKHCFSQLREHQDRAKNNNESILSMGDTNANQIMLEVSSPNDEPRTRDLDDEIGNANVSRPQYHSHSQKQPPQPQGFGKGAQAASTSQRDFHPSLVVHRQPSEEHTVKRAILQTPQSVQGPGLASWRNAVGQASLEGSAKRDAEVPRHIPKDKLAKTLDNEELKRASSSAASAGSLIWENLQPMRLDTSEPQGLVPGRGEGPQGTLAGHTPGTVLSVGEGTSAGRCVCPPKPSTSEARGSIPSVTKMEGTHGLDLYSECIPHPESTPNSASALMEIPSPSHPEVFVGQGTGELKVERKYLQPRNEQGLKSSQAQGLGCHEEKSMSPVERKELHEKTHQEATSQLNSSHHQLKVGEGSGLEEMMGVSAGVEGFQQATPAQSTAPGEGGTRLTGKTSPGALGRTMRETASSDFAPSDGHIACVLRDTESISSEVSREERSQGSQNGGSAKALAAGPSVGGNRAEAPELLGPHSGNSEARKGRETATPVAEDRNRLENAAQTEVAPAGGDSVFSTSAPLHPETTVNLTHHPTPQGSSSQFSVDTGSTLVALPPTDGGQVLNTSLKVPDKSTCPSGIPKPLSHPKDAPSSQEATEKLEMEKVEERTETKPVLMPKPKHVRPKIITYIRRNPQALGQGDASLVPVGLPYAPPSCGMPLPQEEKTANRDLQPSANMYEKFKPDLQKPRVFPSGLMVSGIKPPGHHFSQMSEKFLQEVTDHPGKEEFCSPPYTHYEVPPTFYRSAMLLKPQLGLGAMSRLPSTKSRILIASQRSSASAIHPPGPITTAASFYGSDPSDLKKTSNSNAAKSSLPKSGLRPPGYSRLPAAKLAAFGFVRSSSVSAVPSTQSMDTVQPEQSRPATRSAFGNEEQPPLKPAPPSKDTPKGTGRAAPTPSSNAATPRRSLLPAPKSTSMPAGTKKEAQKDPDANKPAVSSPKRTAASSTKLHSPGYPKQRTTASRNGITPKPDLQAREAERQLAQRLRDRCEWQARQLGLARGELKKAIRGFDALAVSTQHFFGKSESALSKEKELSIELANIRDEVAFNTAKCEKLQKEKEALERRFEEELRRLGWQQQAEVQELQERLQQQFQAESAHLQAEHQDQLLRMRCQHQEQVEDITASHEAALLEMENNHTVAITILQDDHDHKVQELMATHEFEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRAQRFEEALRKTTEEQLEIALAPYQHLEEDMQSLKQVLEMKNQQIHLQEKKIIELEKLVEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSPVYRGSSSGPSSPARVSTTPR", "length": 1350, "header": "tr|A0A8C2N0H1-1|A0A8C2N0H1_CRIGR Isoform 1 of Microtubule-associated tumor suppressor candidate 2 OS=Cricetulus griseus OX=10029 GN=Mtus2 PE=4 SV=1 CANONICAL=A0A8C2N0H1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 893, "start_aa": "Thr", "end_pos": 893, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr893", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755920", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755920", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q3UHD3-1", "protein_name": "Microtubule-associated tumor suppressor candidate 2 homolog", "gene_name": "Mtus2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVPLAPKKSCFGQLRDHREGAKNNNESILRTGDTNANQIMLEVSSSCDEAKSRDLDDELGNSNLSRPQYHSHFQKEPLHLQGFGKGSQAGSTSQRESQASLTVHRQLSEEHAVKRGALQAPQCVQGPSLSSWRNAVGQASPEASAKKDAEIPRHIPKDKLAKTLDNEELKRASSCSAAAGSVPPTDLQPVQLDTLGPQDHVPARGEGPQRTPASHSPGKGFSPGEGTSEGNSVYLPKPSTSEAKGSSPSDTKMEGPHGLDVYNERITHAELTPSSASASKENPGLRHPEVCLGQGTGKSKVELKSVQPRNEEGLTSAQAQGPGCHEERSMSPVERQELLEKAYREATSQGNSSHRQLGVRRGSSLEEMTGVSAGVEGSQQATPTLSAAPAGEAGTRLTGKMSAGVGRMARETASGQTAPDVGQAAPVRRDPTESVPSEVSGEERRLGSGNSGSTKLLASGPSAGGSRTDTSGLLSPRGSNLEARKGKEMVAENRNLLENAAQTDNTPAGVDSAFSTPAPLLHPETTVNSSHHPTPPGSSSQELGVFSGDTGSPSVASPPTDGGQVLNTSPKVPDRTTCSSGIPKPPTHPKDTPSSQEAREKLETEKMEERAEAKPILMPKPKHVRPKIITYIRRNPQALSQGDASLVPVGLPYAPPTCGMPLPQEEKAASRDLQPSANMYEKLKPDLQKPRVFPSGLMVSGIKPPAHHFSQMSEKFLQEVADHPGKEEFCSPPYTHYEVPPTFYRSAMLLKPQLGLGAMSRLPSTKSRILIASQRSSASAIHPPGSLTTAASFYGSDPSDLKKASNSNAAKASLPKSGLRPPGYSRLPAAKLAAFGFVRSSSISAVPSSQSLDSVQPEQSRPVTRSTFGNEEQAPLKQALPSKDTPKGAGRAAPASSSNATTPRRSLLPAPKSTSTPAGAKKELQKDPEAKKPAVSSPKRTASAATKPHSPGYPKQRTSAPRNEFPPKPDLQAREAERQLAQRLRDRCEWQARQLGLARRELKKAIQGFDALAVSTKHFFGKSERALAKEKELSIELANIRDEVAFNTAKCEKLQKEKETLERRFEEELRRLGWQQQAEVQELQERLQQQFQAESARLQAEHQDQLLRMRCQHQEQVEDITASHEAALLEMENNHTVAITILQDDHDHKVQELMSTHEFEKKELEENFEKLRLTLQDQVDTLTFQSQSLRDRARRFEEALRKTTEEQLEIALAPYQHLEEDMQSLKQVLEMKNQQIHLQEKKIIELEKLVEKNIILEERIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSPVYRGSSSGPSSPARVSTTPR", "length": 1353 }, "evidence": [ { "id": "A0A8C2N0H1", "url": "https://omabrowser.org/oma/group/A0A8C2N0H1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5JR59-2", "protein_name": "Microtubule-associated tumor suppressor candidate 2", "gene_name": "MTUS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVPVAPKKSCYTQLRDNRNAARNNNESILSLGDTNANQIMLEVSSSHDESKTCDLGDEIGNTNSSEPENRTHFHKEFHQLQGFGKGSQAGSASLKDFRLSSTIQRELNEEHTVERGTDSLQTTRSIQGPSLSSWRNVMSEASLDVLAKRDAEIPRHVPKDKLAKTLDNEELRRHSLERASSSVAAVGSLTPQHPQPLSLDSREARGQIPGGGEGPQKTLPDHAVPAAFPATDSTSEGKSVRHPKPSTSESKQSTPSETQTVGAHVLQVCSEHTSHSAHPEPALNLTLASKEIPSKLEAQLGQGKGEAKLDLKYVPPRRVEQEGKAAQEGYLGCHKEENLSALEGRDPCGEAHPEATDALGHLLNSDLHHLGVGRGNCEEKRGVNPGEQDSLHTTPKQGSASLGGADNQPTGKISPCAGEKLGERTSSSFSPGDSHVAFIPNNLTDSKPLDVIEEERRLGSGNKDSVMVLVFNPSVGENKTEVPEPLDPQSGRSEARESKEVTTSVAENRNLLENADKIESTSARADSVLNIPAPLHPETTVNMTYQPTTPSSSFQDVSVFGMDAGSPLVVPPPTDSARLLNTSPKVPDKNTCPSGIPKPVFTHSKDTPSSQEGMENYQVEKTEERTETKPIIMPKPKHVRPKIITYIRRNPQALGQVDASLVPVGLPYAPPTCTMPLPHEEKAAGGDLKPSANLYEKFKPDLQKPRVFSSGLMVSGIKPPGHPFSQMSEKFLQEVTDHPGKEEFCSPPYAHYEVPPTFYRSAMLLKPQLGLGAMSRLPSAKSRILIASQRSSASAIHPPGPITTATSLYSSDPSADLKKASSSNAAKSNLPKSGLRPPGYSRLPAAKLAAFGFVRSSSVSSVSSTQSGDSAQPEQGRPATRSTFGNEEQPVLKASLPSKDTPKGAGRVAPPASSSVTAPRRSLLPAPKSTSTPAGTKKDAQKDQDTNKPAVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSPVYRGSSSGPSSPARVSTTPR", "length": 1369 }, "evidence": [ { "id": "A0A8C2N0H1", "url": "https://omabrowser.org/oma/group/A0A8C2N0H1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H1" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H1" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H1" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H1" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1132, "end_pos": 1134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 530, "end_pos": 532, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 893 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1132, "end_pos": 1134 }, { "start_pos": 26, "end_pos": 28 }, { "start_pos": 352, "end_pos": 354 }, { "start_pos": 530, "end_pos": 532 }, { "start_pos": 565, "end_pos": 567 }, { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N0H4-1", "uniprot_ac": "A0A8C2N0H4", "uniprot_id": "A0A8C2N0H4_CRIGR", "mass": { "chemical_mass": 42042.0, "monoisotopic_mass": 42042.0 }, "refseq": { "ac": "XP_027251926", "name": "malonyl-CoA-acyl carrier protein transacylase, mitochondrial isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251926" }, "gene_names": [ { "name": "Mcat", "type": "recommended", "evidence": [ { "id": "A0A8C2N0H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4" } ] }, { "name": "Mcat", "type": "synonym", "evidence": [ { "id": "XP_027251926", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251926" } ] } ], "protein_names": [ { "name": "Malonyl-CoA-acyl carrier protein transacylase, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8C2N0H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.39", "type": "synonym", "evidence": [ { "id": "A0A8C2N0H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4/entry#names_and_taxonomy" } ] }, { "name": "Mitochondrial malonyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8C2N0H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4/entry#names_and_taxonomy" } ] }, { "name": "[Acyl-carrier-protein] malonyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8C2N0H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4/entry#names_and_taxonomy" } ] }, { "name": "malonyl-CoA-acyl carrier protein transacylase, mitochondrial isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027251926", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251926" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027251926", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251926" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mcat", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4", "locus": {} } ], "crossref": [ { "id": "100770744", "url": "https://www.ncbi.nlm.nih.gov/gene/100770744", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052760", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052760", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770744", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770744", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N0H4", "url": "https://www.orthodb.org/?gene=A0A8C2N0H4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47170:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47170:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00698", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00698", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027251926", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251926", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "41792", "url": "https://www.rhea-db.org/rhea/41792", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N0H4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FAZ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FAZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FAZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FAZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCFVMSARVARAGWSWGLWGRRAASSLREPPPDAVDVAELLRDASSAQDEAPEALAPRPPSRCSVLLFPGQGSQMVGMGGGLLGFPRVRQLYEAAHRVLGYDLLELCLHGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIENCVAAAGFSVGEFAALVFAGAMEFSEGLYAVKVRAEAMQEASEAVPSGMLSVLGQRQSNFSLACMEAQEHCRSLGIENPVCQVSNYLFPDCRVISGHLEALQFLRKNSAKYHFRRTKMLPVSGGFHTCLMEPAVEPLVKILGTINIKKPLVAVHSNVSGHKYMDPQHIRKLLGQQVVSPVKWEQTMHSIYKRKKGTDFPSTFEVGPGRQLGSILKSCNGQAWKSYNHVDVMQTSTDPDH", "length": 384, "header": "tr|A0A8C2N0H4-1|A0A8C2N0H4_CRIGR Isoform 1 of Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Cricetulus griseus OX=10029 GN=Mcat PE=3 SV=1 CANONICAL=A0A8C2N0H4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N0H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4/entry#A0A8C2N0H4-1", "sequence": { "sequence": "MCFVMSARVARAGWSWGLWGRRAASSLREPPPDAVDVAELLRDASSAQDEAPEALAPRPPSRCSVLLFPGQGSQMVGMGGGLLGFPRVRQLYEAAHRVLGYDLLELCLHGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIENCVAAAGFSVGEFAALVFAGAMEFSEGLYAVKVRAEAMQEASEAVPSGMLSVLGQRQSNFSLACMEAQEHCRSLGIENPVCQVSNYLFPDCRVISGHLEALQFLRKNSAKYHFRRTKMLPVSGGFHTCLMEPAVEPLVKILGTINIKKPLVAVHSNVSGHKYMDPQHIRKLLGQQVVSPVKWEQTMHSIYKRKKGTDFPSTFEVGPGRQLGSILKSCNGQAWKSYNHVDVMQTSTDPDH", "length": 384, "header": "tr|A0A8C2N0H4-1|A0A8C2N0H4_CRIGR Isoform 1 of Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Cricetulus griseus OX=10029 GN=Mcat PE=3 SV=1 CANONICAL=A0A8C2N0H4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FAZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4/entry#A0A9J7FAZ2-1", "sequence": { "sequence": "MCFVMSARVARAGWSWGLWGRRAASSLREPPPDAVDVAELLRDASSAQDEAPEALAPRPPSRCSVLLFPGQGSQMVGMGGGLLGFPRVRQLYEAAHRVLGYDLLELCLHGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIENCVAAAGFSVGEFAALVFAGAMEFSEGPAVSPEEFC", "length": 181, "header": "tr|A0A9J7FAZ2-1|A0A8C2N0H4_CRIGR Computationally mapped isoform of Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Cricetulus griseus OX=10029 GN=Mcat PE=3 SV=1 CANONICAL=A0A8C2N0H4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FAZ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FAZ2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FAZ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FAZ2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770744", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770744", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4" } ], "pmid": "" }, { "name": "mitochondrial small ribosomal subunit assembly", "id": "GO:0180026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180026", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4" } ], "pmid": "" }, { "name": "monocarboxylic acid metabolic process", "id": "GO:0032787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032787", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "[acyl-carrier-protein] S-malonyltransferase activity", "id": "GO:0004314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004314", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4" } ], "pmid": "" }, { "name": "RNA folding chaperone", "id": "GO:0140691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140691", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0H4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "41792", "name": "", "equation": "holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GXD7-1", "A0A8C2N0H4-1" ], "evidence": [ { "id": "41792", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41792" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8C2N0H4", "gene_name": "Mcat", "activity": [ { "ec_number": "2.3.1.39", "activity": "holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA.", "evidence": [ { "id": "A0A8C2N0H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4" } ] }, { "ec_number": "2.3.1.39", "activity": "", "evidence": [ { "id": "A0A8C2N0H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4" } ] } ] }, { "uniprot_ac": "G3GXD7", "gene_name": "Fasn", "activity": [ { "ec_number": "1.1.1.100", "activity": "a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+).", "evidence": [ { "id": "G3GXD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXD7" } ] }, { "ec_number": "1.3.1.39", "activity": "a 2,3-saturated acyl-[ACP] + NADP(+) = a (2E)-enoyl-[ACP] + NADPH + H(+).", "evidence": [ { "id": "G3GXD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXD7" } ] }, { "ec_number": "2.3.1.38", "activity": "holo-[ACP] + acetyl-CoA = acetyl-[ACP] + CoA.", "evidence": [ { "id": "G3GXD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXD7" } ] }, { "ec_number": "2.3.1.39", "activity": "holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA.", "evidence": [ { "id": "G3GXD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXD7" } ] }, { "ec_number": "2.3.1.41", "activity": "a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2.", "evidence": [ { "id": "G3GXD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXD7" } ] }, { "ec_number": "2.3.1.85", "activity": "acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H(+) = a long-chain fatty acid + (n+1) CoA + n CO2 + 2n NADP(+).", "evidence": [ { "id": "G3GXD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXD7" } ] }, { "ec_number": "3.1.2.14", "activity": "hexadecanoyl-[ACP] + H2O = hexadecanoate + holo-[ACP] + H(+).", "evidence": [ { "id": "G3GXD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXD7" } ] }, { "ec_number": "4.2.1.59", "activity": "a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O.", "evidence": [ { "id": "G3GXD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXD7" } ] }, { "ec_number": "2.3.1.39", "activity": "", "evidence": [ { "id": "G3GXD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXD7" } ] }, { "ec_number": "1.3.1.39", "activity": "", "evidence": [ { "id": "G3GXD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXD7" } ] }, { "ec_number": "2.3.1.85", "activity": "", "evidence": [ { "id": "G3GXD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXD7" } ] }, { "ec_number": "4.2.1.59", "activity": "", "evidence": [ { "id": "G3GXD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXD7" } ] }, { "ec_number": "2.3.1.38", "activity": "", "evidence": [ { "id": "G3GXD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXD7" } ] }, { "ec_number": "3.1.2.14", "activity": "", "evidence": [ { "id": "G3GXD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXD7" } ] }, { "ec_number": "1.1.1.100", "activity": "", "evidence": [ { "id": "G3GXD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXD7" } ] }, { "ec_number": "2.3.1.41", "activity": "", "evidence": [ { "id": "G3GXD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXD7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N0H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0H4" }, { "id": "SM00827", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00827" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Malonyl-CoA:ACP transacylase (MAT)", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 383, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.39", "ec_name": "holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA.", "evidence": [ { "id": "2.3.1.39", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.39" }, { "id": "2.3.1.39", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.39" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 204, "end_pos": 206 }, { "start_pos": 301, "end_pos": 303 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N0I4-1", "uniprot_ac": "A0A8C2N0I4", "uniprot_id": "A0A8C2N0I4_CRIGR", "mass": { "chemical_mass": 46964.0, "monoisotopic_mass": 46964.0 }, "refseq": { "ac": "XP_003501113", "name": "zinc finger protein 821", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501113" }, "gene_names": [ { "name": "Znf821", "type": "recommended", "evidence": [ { "id": "A0A8C2N0I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I4" } ] }, { "name": "Znf821", "type": "synonym", "evidence": [ { "id": "XP_003501113", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501113" } ] } ], "protein_names": [ { "name": "Zinc finger protein 821", "type": "recommended", "evidence": [ { "id": "A0A8C2N0I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I4/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 821", "type": "synonym", "evidence": [ { "id": "XP_003501113", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501113" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613830.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003501113", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501113" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I4#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf821", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I4", "locus": {} } ], "crossref": [ { "id": "100756049", "url": "https://www.ncbi.nlm.nih.gov/gene/100756049", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756049", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756049", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NNCVAYR", "url": "https://omabrowser.org/oma/group/NNCVAYR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N0I4", "url": "https://www.orthodb.org/?gene=A0A8C2N0I4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24409", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24409", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24409:SF295", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24409:SF295", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_003501113", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501113", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N0I4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRRKQTNPNKVHWDQVFAGLEEQARQAMMKTDFPGDLGSQQQAIQQLRDQDSSSSDSEGDEEETTQDEVSSHTSEEDGGVVKVEKELENPEQPVGSGNEVVEHEVTESLNSDPLLELCQCPLCQLDCGSREQLIAHVYQHTAAVVSAKSYMCPVCGRALSSPGSLGRHLLIHSEDQRSNCAVCGARFTSHATFNSEKLPEVLNMESLPQVHSEGPSSAEGKDITCSPPVYPAGILLVCNNCAAYRKLLETQTPNVRKWALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRLKRANETPEKRQARLIREREAKRLKRRLEKMDMMLRAQFGQDPSAMAALAAEMNFFQLPVSGVELDSQLLGKMAFEEQNNSSLH", "length": 413, "header": "tr|A0A8C2N0I4-1|A0A8C2N0I4_CRIGR Isoform 1 of Zinc finger protein 821 OS=Cricetulus griseus OX=10029 GN=Znf821 PE=3 SV=1 CANONICAL=A0A8C2N0I4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N0I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I4/entry#A0A8C2N0I4-1", "sequence": { "sequence": "MSRRKQTNPNKVHWDQVFAGLEEQARQAMMKTDFPGDLGSQQQAIQQLRDQDSSSSDSEGDEEETTQDEVSSHTSEEDGGVVKVEKELENPEQPVGSGNEVVEHEVTESLNSDPLLELCQCPLCQLDCGSREQLIAHVYQHTAAVVSAKSYMCPVCGRALSSPGSLGRHLLIHSEDQRSNCAVCGARFTSHATFNSEKLPEVLNMESLPQVHSEGPSSAEGKDITCSPPVYPAGILLVCNNCAAYRKLLETQTPNVRKWALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRLKRANETPEKRQARLIREREAKRLKRRLEKMDMMLRAQFGQDPSAMAALAAEMNFFQLPVSGVELDSQLLGKMAFEEQNNSSLH", "length": 413, "header": "tr|A0A8C2N0I4-1|A0A8C2N0I4_CRIGR Isoform 1 of Zinc finger protein 821 OS=Cricetulus griseus OX=10029 GN=Znf821 PE=3 SV=1 CANONICAL=A0A8C2N0I4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756049", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756049", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XY16-1", "protein_name": "Zinc finger protein 821", "gene_name": "ZNF821", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQRQSDFLSLWLPGEQVFAGLEEQARQAMMKNSFPGALGDQRPAIHPLQDRDFSSSGSDDEETTHDEVSSHTSEEDGSMLKVKKELENAEQHAAGTPLMRENEVPASLNADSMLGLSKCPLCQLEYESREQLIAHVYQHTAAVVSAKSYMCPVCGRALSSPGSLGRHLLIHSEDQLSNCAVCGARFTSHATFNSEKLTEVLSADRLPMPQSEGPSSIKGKDITFHSPVYPAGILLVCNNCAAYRKLLEAQTPGMRKWALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRVKRANETPEKRQARLIREREAKRLKRRLEKMDMMLRAQFGQDPSAMAALAAEMNFFQLPVGNVELENQLLGKMTFEEQSNSMLH", "length": 412 }, "evidence": [ { "id": "A0A8C2N0I4", "url": "https://omabrowser.org/oma/group/A0A8C2N0I4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1S3C6-1", "protein_name": "Zinc finger protein 821", "gene_name": "ZNF821", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRRKQTNPNKVHWDQVFAGLEEQARQAMMKTDFPGDLGSQRQAIQQLRDQDSSSSDSEGDEEETTQDEVSSHTSEEDGGVVKVEKELENAEQPVGGNKVVEHEVTENLNSDPLLGLCQCPLCQLDCGSREQLIAHVYQHTAAVVSAKSYMCPVCGRALSSPGSLGRHLLIHSEDQRSNCAVCGARFTSHATFNSEKLPEVLNMESLPPAHSEGPSSAEGKDIAFSPPVYPAGILLVCNNCAAYRKLLEAQTPSVRKWALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRLKRANETPEKRQARLIREREAKRLKRRLEKMDMMLRAQFGQDPSAMAALAAEMNFFQLPVSGVELDSQLLGKMAFEEQNNSSLH", "length": 412 }, "evidence": [ { "id": "A0A8C2N0I4", "url": "https://omabrowser.org/oma/group/A0A8C2N0I4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75541-1", "protein_name": "Zinc finger protein 821", "gene_name": "ZNF821", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRRKQTNPNKVHWDQVFAGLEEQARQAMMKTDFPGDLGSQRQAIQQLRDQDSSSSDSEGDEEETTQDEVSSHTSEEDGGVVKVEKELENTEQPVGGNEVVEHEVTGNLNSDPLLELCQCPLCQLDCGSREQLIAHVYQHTAAVVSAKSYMCPVCGRALSSPGSLGRHLLIHSEDQRSNCAVCGARFTSHATFNSEKLPEVLNMESLPTVHNEGPSSAEGKDIAFSPPVYPAGILLVCNNCAAYRKLLEAQTPSVRKWALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRLKRANETPEKRQARLIREREAKRLKRRLEKMDMMLRAQFGQDPSAMAALAAEMNFFQLPVSGVELDSQLLGKMAFEEQNSSSLH", "length": 412 }, "evidence": [ { "id": "A0A8C2N0I4", "url": "https://omabrowser.org/oma/group/A0A8C2N0I4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q32KS7-1", "protein_name": "Zinc finger protein 821", "gene_name": "ZNF821", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRRKQTNPNKVHWDQVFAGLEEQARQAMMKTDFPGDLGSQRQAIQQLRDQDSSSSDSEGDEEETTQDEVSSHTSEEDGGVVKVEKELENAEQPVGGKKVVEHEVTENLHSDPLLGLCQCPLCQLDCGSREQLIAHVYQHTAAVVSAKSYMCPVCGRALSSPGSLGRHLLIHSEDQRSNCAVCGARFTSHATFNSEKLPEVLNVESLPPAHSEGPSSAEGKDIAFTPPVYPAGILLVCNNCAAYRKLLEAQTPSVRKWALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRLKRANETPEKRQARLIREREAKRLKRRLEKMDMMLRAQFGQDPSAMAALAAEMNFFQLPVSGVELDSQLLGKMAFEEQNSSSLH", "length": 412 }, "evidence": [ { "id": "A0A8C2N0I4", "url": "https://omabrowser.org/oma/group/A0A8C2N0I4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PD05-1", "protein_name": "Zinc finger protein 821", "gene_name": "Znf821", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRRKQTNPNKVHWDQVFAGLEEQARQAMMKTDFPGDLGSQRQAIQQLRDQDSSSSDSEGDEEETTQDEVSSHTSEEDGGVVKVEKELETAEAPVSSGDALAEREVTENLNSDPLLQLCQCPLCQLDCGSREQLIAHVYQHTAAVVSAKSYMCPVCGRALSSPGSLGRHLLIHSEDQRSNCAVCGARFTSHATFNSEKLPQVLNMESVPQVHSEGPSSAEGKDIACSPPVYPAGILLVCNNCAAYRKLLETQTPSVRKWALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRLKRANETPEKRQARLIREREAKRLKRRLEKMDMMLRAQFGQDPSAMAALAAEMNFFQLPVSGVELDSQLLGKMAFEEQNNSSLH", "length": 413 }, "evidence": [ { "id": "A0A8C2N0I4", "url": "https://omabrowser.org/oma/group/A0A8C2N0I4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I4" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N0I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 151, "end_pos": 178, "start_aa": "Tyr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 288, "end_pos": 290 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 408, "end_pos": 410 }, { "start_pos": 409, "end_pos": 411 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N0I6-1", "uniprot_ac": "A0A8C2N0I6", "uniprot_id": "A0A8C2N0I6_CRIGR", "mass": { "chemical_mass": 45594.0, "monoisotopic_mass": 45594.0 }, "refseq": { "ac": "XP_003511007", "name": "12S rRNA N4-methylcytidine (m4C) methyltransferase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511007" }, "gene_names": [ { "name": "Mettl15", "type": "recommended", "evidence": [ { "id": "A0A8C2N0I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I6" } ] }, { "name": "Mettl15", "type": "synonym", "evidence": [ { "id": "XP_003511007", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511007" } ] } ], "protein_names": [ { "name": "12S rRNA N(4)-cytidine methyltransferase METTL15", "type": "recommended", "evidence": [ { "id": "A0A8C2N0I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I6/entry#names_and_taxonomy" } ] }, { "name": "12S rRNA N4-methylcytidine (m4C) methyltransferase", "type": "synonym", "evidence": [ { "id": "XP_003511007", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511007" } ] }, { "name": "Methyltransferase 5 domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A8C2N0I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I6/entry#names_and_taxonomy" } ] }, { "name": "Methyltransferase-like protein 15", "type": "synonym", "evidence": [ { "id": "A0A8C2N0I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614993.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003511007", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511007" } ] }, { "annotation": "N4-methylcytidine (m4C) methyltransferase responsible for the methylation of position C839 in mitochondrial 12S rRNA. Involved in the stabilization of 12S rRNA folding, therefore facilitating the assembly of the mitochondrial small ribosomal subunits.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I6#function" }, { "database": "UniProtKB", "id": "ARBA00056391", "url": "https://www.uniprot.org/uniprotkb/ARBA00056391#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mettl15", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I6", "locus": {} } ], "crossref": [ { "id": "100770656", "url": "https://www.ncbi.nlm.nih.gov/gene/100770656", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770656", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770656", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NPAKRTF", "url": "https://omabrowser.org/oma/group/NPAKRTF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N0I6", "url": "https://www.orthodb.org/?gene=A0A8C2N0I6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11265", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11265", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11265:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11265:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01795", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01795", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003511007", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511007", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "62524", "url": "https://www.rhea-db.org/rhea/62524", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N0I6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRYSYFCKLYKELFYCWMESGAFNLGICPQAMHTTAAVHTEYESLEETALCGTGKVHRSAEEDSEAIAKLHIPVMVDEVVHCLTPQKGQVFLDMTFGSGGHTKAILQKEPDITIYALDRDPTAYAIAEKLSEVYPKQIQAMLGQFSEAEALLINAGVQPGTIDGVLLDLGCSSMQLDAPERGFSLRKDGPLDMRMDGDRYPDMPTAADVVNGLDQQALASILRAYGEEKHAKKIASAIIQARSIYPILRTQQLASIVAGAFPPSAVYARKDLLQRSSHIATKTFQALRIFVNNELNELYTGLKTAQKFLKTGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSIRQKVKQRSQMDSNIENDRSERGSSVRAPLNWDLLHKKVLTPEDQDVQENPRGRSAKLRAAIKL", "length": 409, "header": "tr|A0A8C2N0I6-1|A0A8C2N0I6_CRIGR Isoform 1 of 12S rRNA N(4)-cytidine methyltransferase METTL15 OS=Cricetulus griseus OX=10029 GN=Mettl15 PE=3 SV=1 CANONICAL=A0A8C2N0I6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N0I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I6/entry#A0A8C2N0I6-1", "sequence": { "sequence": "MLRYSYFCKLYKELFYCWMESGAFNLGICPQAMHTTAAVHTEYESLEETALCGTGKVHRSAEEDSEAIAKLHIPVMVDEVVHCLTPQKGQVFLDMTFGSGGHTKAILQKEPDITIYALDRDPTAYAIAEKLSEVYPKQIQAMLGQFSEAEALLINAGVQPGTIDGVLLDLGCSSMQLDAPERGFSLRKDGPLDMRMDGDRYPDMPTAADVVNGLDQQALASILRAYGEEKHAKKIASAIIQARSIYPILRTQQLASIVAGAFPPSAVYARKDLLQRSSHIATKTFQALRIFVNNELNELYTGLKTAQKFLKTGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSIRQKVKQRSQMDSNIENDRSERGSSVRAPLNWDLLHKKVLTPEDQDVQENPRGRSAKLRAAIKL", "length": 409, "header": "tr|A0A8C2N0I6-1|A0A8C2N0I6_CRIGR Isoform 1 of 12S rRNA N(4)-cytidine methyltransferase METTL15 OS=Cricetulus griseus OX=10029 GN=Mettl15 PE=3 SV=1 CANONICAL=A0A8C2N0I6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770656", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770656", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AC58FZ98-1", "protein_name": "12S rRNA N(4)-cytidine methyltransferase METTL15", "gene_name": "mettl15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTYDAATEWTESIESRMMKNLIYGGYMGWNKARNVSYIEHYDFYAIRYSRIYMPQYYSCFMAAPCRQTLGVWKHVATLRNPRMFRRCWRKSWHPGRLYTGSVPSSPDCEMPVQEEKPFHTPVMVKEVLQFLNIKPGQIVLDLTFGAGGHSKAILQSVPGVTVVAADRDPTAFRMAQQLAEEYQGKVKPVLGRFSELNNLLPALGLGPGTVDAALLDAGCSSMQMDSAERGFSLSKDGPLDMRMDGDRYPDMPCAADVVNALDQQALASVLAAYGEERHTRKIAAAIAQARSVYPIGRTLQLASIVAGAFPASALYARRDRLQRPSHVATKTFQALRIFVNDELNELHAGLRVAQTLLRPKGRLCVLTFHSLEDRLTKRFLRGEDLAAPPRRSLRQHARARPAGQEEEFEEEEEGDEGGNSVHWVSLKKVIKPSEEEVQENPRARSAKLRTAVRQ", "length": 454 }, "evidence": [ { "id": "A0A8C2N0I6", "url": "https://omabrowser.org/oma/group/A0A8C2N0I6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0JN95-1", "protein_name": "12S rRNA N(4)-cytidine methyltransferase METTL15", "gene_name": "METTL15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLRYPYFCRIHKNFLSCWLESGIYNLGVWPKKIHATAERYNEYEAQEETDQTGIQELHRSQDRDSGVMTKLHIPVMVDEVVRCLAPQKGQVFLDMTFGSGGHTRAILQKEPDITLYALDRDPTAYAIAEQLSELYPKQIRAILGQFSQAEALLMKAGVQPGTLDGVLLDLGCSSMQLDTPERGFSLRKDGPLDMRMDGDRYPDMPTAADVVNALDQQALASILRAYGEEKHAKKIASAIIQARGLYPITRTQQLASIVAGAFPPSALYARKDLLQRPTHIATKTFQAFRIFVNNELNELYTGLKTAQKFLRPGGHLVALSFHSLEDRIIKRFLLGISMTERFNLSARQKVIQKSQLDSDQENKEGVSTGKAPLMWKLIHKKVLTPEDEDVQDNPRGRSAKLRAAIKL", "length": 407 }, "evidence": [ { "id": "A0A8C2N0I6", "url": "https://omabrowser.org/oma/group/A0A8C2N0I6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A6NJ78-1", "protein_name": "12S rRNA N(4)-cytidine methyltransferase METTL15", "gene_name": "METTL15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRYPYFCRMYKECLSCWLESGIPNLGVWPNRIHTTAEKYREYEAREQTDQTQAQELHRSQDRDFETMAKLHIPVMVDEVVHCLSPQKGQIFLDMTFGSGGHTKAILQKESDIVLYALDRDPTAYALAEHLSELYPKQIRAMLGQFSQAEALLMKAGVQPGTFDGVLMDLGCSSMQLDTPERGFSLRKDGPLDMRMDGGRYPDMPTAADVVNALDQQALASILRTYGEEKHAKKIASAIVQARSIYPITRTQQLASIVAGAFPPSAIYTRKDLLQRSTHIATKTFQALRIFVNNELNELYTGLKTAQKFLRPGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSVRQQVMKTSQLGSDHENTEEVSMRRAPLMWELIHKKVLSPQDQDVQDNPRGRSAKLRAAIKL", "length": 407 }, "evidence": [ { "id": "A0A8C2N0I6", "url": "https://omabrowser.org/oma/group/A0A8C2N0I6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F7F172-1", "protein_name": "12S rRNA N(4)-cytidine methyltransferase METTL15", "gene_name": "Mettl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRYPYFCRTYNRLFSYFVDSGAFNLDVCPHTIHTTAAMHTEYKASEGIALCDTQKVYRSEETDSEAMAKLHIPVMVDEVVQCLTPQKGQVFLDMTFGSGGHSKAILQKEPDVTVYALDRDPVAFTLAERLSEMYPTQIHAMLGQFSQAETLLMKAGVQPGTVDGVLLDLGCSSMQLDAPERGFSLRKDGPLDMRMDGDRYPDMPTAADVVNALDQQALASILRAYGEEKHAKKIASAIIQARSTYPISRTQQLASIVAGAFPPSAIYARKDLLQRSTHIATKTFQALRIFVNNELNELYTGLRTAQKFLKPGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSIRQKVRQTSQMDSDHEIEERRCVRAPLKWELIHKKVLTPEDQDVQANPRGRSAKLRAAIKL", "length": 406 }, "evidence": [ { "id": "A0A8C2N0I6", "url": "https://omabrowser.org/oma/group/A0A8C2N0I6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54PT4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKLFNNNNNLIRFQQILKRNYSNKKVKNVEDINIDSSNDNNTLVQQYVNKEYESYKIHKPVFIKEVLEILNPQPNKVYIDATFGMGGHSRGILETCKDCYVIAFDRDPKVFEMTKPLRSEFKDRLITINSTFSSMRSALKEKNLDHLKISGILYDFGVSSYQIDTADRGFSFKKELEGPLDMRMNQNSSQITAYDIINTFSEKDLRDIFFYYGEEKHTKNIANEILRKRKIEPIKNTSDLVKIVESSIPYPMALKTISRVFRSLRMFVNDELNEIKIGLTQGEQLLEPNSPLLAISFHSIEDRIVKQYLNKYTTIEEPTFKFSPTYKSPIFPSKEELEWNPRSKSAILRTAIRTSNKPISSNYNII", "length": 367 }, "evidence": [ { "id": "A0A8C2N0I6", "url": "https://omabrowser.org/oma/group/A0A8C2N0I6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9DCL4-1", "protein_name": "12S rRNA N(4)-cytidine methyltransferase METTL15", "gene_name": "Mettl15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRYPYFYRTYNRLFSHFVDSGASNLDVCPHTIHTAVALHTESKAVEGTALCGPQKVYSSEEKELEAMAKLHIPVMVDQVVHCLAPQKGQVFLDMTFGSGGHTRAILQKEPDVMVYALDRDPVAYAIAEQLSRLYPTQIQALLGQFSQAEALLMKAGVQPGTIDGILMDLGCSSMQLDAPERGFSLRKDGPLDMRMDGDRYPDTPTASDVVNALDQQALASILRAYGEEKHAKKIASAIIQARSTYPISRTQQLASIVAGAFPPSAVYARKDLLQRSTHIATKTFQALRIFVNNELNELYAGLRTAEKFLKTGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSIRQKVKQTSQLDSDQETEERHSVRAPLKWELIHKKVLTPEDQDVQDNPRGRSAKLRAAIKL", "length": 406 }, "evidence": [ { "id": "A0A8C2N0I6", "url": "https://omabrowser.org/oma/group/A0A8C2N0I6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LEU9-1", "protein_name": "MraW methylase family protein", "gene_name": "CMAL", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGVIRAKQLFLCSSILSSNNNKVLSRLPRRSINVIAGNLNSSETKKKEKEKRKRRKEIEVEKATAEAVVNKEKRRTRSSRGYELADGDEVPSSHVPVMLGEVLDIFSSVRLRSFVDCTLGAAGHSSSIIQSHSELKNFVGMDVDPVARKLGHFHIDSLMHPTLKASIVLKNFKYIKSVIADTQPELLDVGVDGILMDLGMSSMQVNNPERGFSVLQEGPLDMRMDPQATLTAEDIVNSWPESELGRVLRDYGEESNWYLLQNRIVKARLNGGLHSTGELVDLIRGTSPASRGGRQGWIKTATRVFQGLRIAVNDELKTLQNSLYSSFDVLAPGGRLAVISFHSLEDRVVKQTFLDILGFQREEINGEGSSVKPERQIEERVEKELKEKEEWIKQTVIASKGVILTKRPITPSEEEERLNRRARSAKLRVIQKL", "length": 434 }, "evidence": [ { "id": "A0A8C2N0I6", "url": "https://omabrowser.org/oma/group/A0A8C2N0I6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VGY5-1", "protein_name": "Probable methyltransferase-like protein 15 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKRLLNPTRLRLDWLRRSSIDVTTAPHVPVLCDTAIEYLQPVPGGTYFDMTFGAGGHTRRLLEKCPEAKVYALDRDPLAHQLARDMSESEEFKGRLIPLLGKFSDLPKLFKEHGLAKNSVDGMLFDFGCSSMQFDEAVRGFSISRDGPLDMRMDGGHSGGVTAADVLANVEEGDLVKILRMYGEEKAAKKIARGLVDARNALFKIETTKQLADIIENIMDGGTRKDKLRRPAHSATKTFQAIRIFVNNELNEINYGMVLANEILRVDGRLVTITFHSLEDTIVKRHINGNVLAGAANALPLKYSSHYAIDEPDILESLTKKSWKQLHRHVIVPDADEVARNTRSRSAKLRAAVKTN", "length": 356 }, "evidence": [ { "id": "A0A8C2N0I6", "url": "https://omabrowser.org/oma/group/A0A8C2N0I6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA base methylation", "id": "GO:0070475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070475", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I6" } ], "pmid": "" }, { "name": "mitochondrial small ribosomal subunit assembly", "id": "GO:0180026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180026", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "rRNA (cytosine-N4-)-methyltransferase activity", "id": "GO:0071424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071424", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0I6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0I6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "62524", "name": "", "equation": "cytidine(839) in 12S rRNA + S-adenosyl-L-methionine = N(4)-methylcytidine(839) in 12S rRNA + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "62524", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62524" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 343, "end_pos": 345 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { 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"XP_007647203", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647203" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614533.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007647203", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647203" } ] }, { "annotation": "Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. Promotes clustering of HT2RC at the cell surface.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FDP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDP7#function" }, { "database": "UniProtKB", "id": "ARBA00057502", "url": "https://www.uniprot.org/uniprotkb/ARBA00057502#function" }, { "database": "UniProtKB", "id": "A0A8C2N0K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0K3#function" }, { "database": "UniProtKB", "id": "A0A9J7J918", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J918#function" }, { "database": "UniProtKB", "id": "A0A9J7JEI2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JEI2#function" }, { "database": "UniProtKB", "id": "A0A9J7JEQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JEQ0#function" }, { "database": "UniProtKB", "id": "A0A9J7GTY4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTY4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0K3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mpdz", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0K3", "locus": {} } ], "crossref": [ { "id": "cd06667", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06667", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06668", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06668", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06669", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06669", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06670", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06670", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06671", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06671", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06672", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06672", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06673", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06673", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06674", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06674", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06675", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06675", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06676", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06676", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06689", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06689", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06791", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06791", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10817", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10817", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752160", "url": "https://www.ncbi.nlm.nih.gov/gene/100752160", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752160", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752160", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N0K3", "url": "https://www.orthodb.org/?gene=A0A8C2N0K3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FC50", "url": "https://www.orthodb.org/?gene=A0A9J7FC50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FDP7", "url": "https://www.orthodb.org/?gene=A0A9J7FDP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J918", "url": "https://www.orthodb.org/?gene=A0A9J7J918", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JEI2", "url": "https://www.orthodb.org/?gene=A0A9J7JEI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JEQ0", "url": "https://www.orthodb.org/?gene=A0A9J7JEQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19964", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19964", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19964:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19964:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09045", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09045", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16667", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16667", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007647203", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647203", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N0K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0K3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0K3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FC50", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FC50-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FDP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FDP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GTY4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GTY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J918", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J918", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J918-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J918-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JEI2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JEI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JEI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JEI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JEQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JEQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JEQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JEQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLETIDKNRALQAAERLQNKLKERGDVANEDKLSLLKSVLQSPLFSQILNLQTSLQQLKDQVNIATLATTNADPAHTPQLSSSSIPTLQSESLLLSPNNGNLEPLSGSGAPPVTVGKPAFDELDQLIKNMAQGRHVEIFELLKPPCGGLGFSVVGLRSENRGELGIFVQEIQEGSVAYRDGRLKEMDQILAINGQFLDQTITHQQAISILQKAKDTVQLVVARGSLPQVSSPRISRSPSAASTVSAHSNPIHWQHVETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVLRQCGNRVKLVIARGAVEETAAPSSLGITLSSSPVSTSEMRVDASTQKSEESEMFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKCSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVRLTLMRKGARQEAELTSREDAAKDVDVPPGDATVSKENYEKDEESLSLRRNISILPIEEEGYPLLSTQLEEAEDVQQEAALLTKWQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNILKELPIDVTMVCCRRTVPPTASSELDGLDISDLELTEKPHIDLGEFIGSSETEDPVLAIPDVDQNAEEIQTPVAMWEAGIQSIELEKGSRGLGFSILDYQDPIDPTSTVIVIRSLVPGGIAEKDGRLVPGDRLMFVNDINLENSSLEEAVEALKGAPSGMVRIGVAKPLPLSPEEGYVSAKEDMFLCPPHSCKEPGLPDKALFRADLALIDAPDAESVAESRFDSPFSPDNDSVYSTQASVLSLQDSACSDGMNYGPSLPSSPPKDVTGSSDLVLGLHLSLEELYTQNLLPRQQAASPLPDRSMAATSGSAIGDYPPANAVEQKYECANTVAWTHSQLPSGLCATELAPALPTAAQKGSEYLTEESSLASDAESVPLQSMSQETFERTVTIAKGSSSLGMTVSANKDGLGVIVRSIIHGGAISRDGRIAVGDCILSINEESTISLTNAQARAMLRRHSLIGPDIKITYVPAEHLEEFRISFGQQSGGIMALDIFSSYTGRDIPELPEREEGEGEESELQNAGYSSWSQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIIEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKFPLPSLPHNLYPKYSFSSTNPFADSLQLATDKAPNQSASDSEKAPMCDVPPSSPSGFSEMGSDCAQPSTITVSEDADKEDEFGYSWKNIQERYGSLSGQLHMIELEKGHSGLGLSLAGNKDRTRMSVFIVGIDPTGAAGRDGRLQVADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNEDAVNQMAVCPGNAADPLPSISESPQNKEVEPSVTTSAALDLSSLTNVYHLELPKDQGGLGIAISEEDTLNGLVIKSITEHGEAAKDGRLKAGDQILAVDDEVVAGCPVEKFISLLKTAKATVKLTVRAENPACQAVPSAASSASGERKESAQSPAVPTLDPDSIPNTSRSSTPAVFASDPATCPIIPGCETTIEISKGQTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEDVCDTFTIDLQKRPGKGLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVTLEVGRIKAGPFHSERRPSQSSQVSDSSLSSFTLPLSGINASESLESNSKKNALASEIQGLRTVEIKKGPSDSLGISIAGGVGSPLGDVPIFIAMMHPNGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLMKNAPGSIEMQVVAGGDVSVVTGHQQELANPCLAFTGLTSSSIFPDDLGPPQCKTITLDRGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLVVLS", "length": 2064, "header": "tr|A0A8C2N0K3-1|A0A8C2N0K3_CRIGR Isoform 1 of Multiple PDZ domain protein OS=Cricetulus griseus OX=10029 GN=Mpdz PE=4 SV=1 CANONICAL=A0A8C2N0K3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N0K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0K3/entry#A0A8C2N0K3-1", "sequence": { "sequence": "MLETIDKNRALQAAERLQNKLKERGDVANEDKLSLLKSVLQSPLFSQILNLQTSLQQLKDQVNIATLATTNADPAHTPQLSSSSIPTLQSESLLLSPNNGNLEPLSGSGAPPVTVGKPAFDELDQLIKNMAQGRHVEIFELLKPPCGGLGFSVVGLRSENRGELGIFVQEIQEGSVAYRDGRLKEMDQILAINGQFLDQTITHQQAISILQKAKDTVQLVVARGSLPQVSSPRISRSPSAASTVSAHSNPIHWQHVETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVLRQCGNRVKLVIARGAVEETAAPSSLGITLSSSPVSTSEMRVDASTQKSEESEMFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKCSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVRLTLMRKGARQEAELTSREDAAKDVDVPPGDATVSKENYEKDEESLSLRRNISILPIEEEGYPLLSTQLEEAEDVQQEAALLTKWQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNILKELPIDVTMVCCRRTVPPTASSELDGLDISDLELTEKPHIDLGEFIGSSETEDPVLAIPDVDQNAEEIQTPVAMWEAGIQSIELEKGSRGLGFSILDYQDPIDPTSTVIVIRSLVPGGIAEKDGRLVPGDRLMFVNDINLENSSLEEAVEALKGAPSGMVRIGVAKPLPLSPEEGYVSAKEDMFLCPPHSCKEPGLPDKALFRADLALIDAPDAESVAESRFDSPFSPDNDSVYSTQASVLSLQDSACSDGMNYGPSLPSSPPKDVTGSSDLVLGLHLSLEELYTQNLLPRQQAASPLPDRSMAATSGSAIGDYPPANAVEQKYECANTVAWTHSQLPSGLCATELAPALPTAAQKGSEYLTEESSLASDAESVPLQSMSQETFERTVTIAKGSSSLGMTVSANKDGLGVIVRSIIHGGAISRDGRIAVGDCILSINEESTISLTNAQARAMLRRHSLIGPDIKITYVPAEHLEEFRISFGQQSGGIMALDIFSSYTGRDIPELPEREEGEGEESELQNAGYSSWSQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIIEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKFPLPSLPHNLYPKYSFSSTNPFADSLQLATDKAPNQSASDSEKAPMCDVPPSSPSGFSEMGSDCAQPSTITVSEDADKEDEFGYSWKNIQERYGSLSGQLHMIELEKGHSGLGLSLAGNKDRTRMSVFIVGIDPTGAAGRDGRLQVADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNEDAVNQMAVCPGNAADPLPSISESPQNKEVEPSVTTSAALDLSSLTNVYHLELPKDQGGLGIAISEEDTLNGLVIKSITEHGEAAKDGRLKAGDQILAVDDEVVAGCPVEKFISLLKTAKATVKLTVRAENPACQAVPSAASSASGERKESAQSPAVPTLDPDSIPNTSRSSTPAVFASDPATCPIIPGCETTIEISKGQTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEDVCDTFTIDLQKRPGKGLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVTLEVGRIKAGPFHSERRPSQSSQVSDSSLSSFTLPLSGINASESLESNSKKNALASEIQGLRTVEIKKGPSDSLGISIAGGVGSPLGDVPIFIAMMHPNGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLMKNAPGSIEMQVVAGGDVSVVTGHQQELANPCLAFTGLTSSSIFPDDLGPPQCKTITLDRGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLVVLS", "length": 2064, "header": "tr|A0A8C2N0K3-1|A0A8C2N0K3_CRIGR Isoform 1 of Multiple PDZ domain protein OS=Cricetulus griseus OX=10029 GN=Mpdz PE=4 SV=1 CANONICAL=A0A8C2N0K3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FC50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0K3/entry#A0A9J7FC50-1", "sequence": { "sequence": "MLETIDKNRALQAAERLQNKLKERGDVANEDKLSLLKSVLQSPLFSQILNLQTSLQQLKDQVNIATLATTNADPAHTPQLSSSSIPTLQSESLLLSPNNGNLEPLSGSGAPPVTVGKPAFDELDQLIKNMAQGRHVEIFELLKPPCGGLGFSVVGLRSENRGELGIFVQEIQEGSVAYRDGRLKEMDQILAINGQFLDQTITHQQAISILQKAKDTVQLVVARGSLPQVSSPRISRSPSAASTVSAHSNPIHWQHVETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVLRQCGNRVKLVIARGAVEETAAPSSLGITLSSSPVSTSEMRVDASTQKSEESEMFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKCSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVRLTLMRKGARQEAELTSREDAAKDVDVPPGDATVSKENYEKDEESLSLRRNISILPIEEEGYPLLSTQLEEAEDVQQEAALLTKWQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNILKELPIDVTMVCCRRTVPPTASSELDGLDISDLELTEKPHIDLGEFIGSSETEDPVLAIPDVDQNAEEIQTPVAMWEAGIQSIELEKGSRGLGFSILDYQDPIDPTSTVIVIRSLVPGGIAEKDGRLVPGDRLMFVNDINLENSSLEEAVEALKGAPSGMVRIGVAKPLPLSPEEGYVSAKEDMFLCPPHSCKEPGLPDKALFRADLALIDAPDAESVAESRFDSPFSPDNDSVYSTQASVLSLQDSACSDGMNYGPSLPSSPPKDVTGSSDLVLGLHLSLEELYTQNLLPRQQAASPLPDRSMAATSGSAIGDYPPANAVEQKYECANTVAWTHSQLPSGLCATELAPALPTAAQKGSEYLTEESSLASDAESVPLQSMSQETFERTVTIAKGSSSLGMTVSANKDGLGVIVRSIIHGGAISRDGRIAVGDCILSINEESTISLTNAQARAMLRRHSLIGPDIKITYVPAEHLEEFRISFGQQSGGIMALDIFSSYTGRDIPELPEREEGEGEESELQNAGYSSWSQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIIEAPNQSASDSEKAPMCDVPPSSPSGFSEMGSDCAQPSTITVSEDADKEDEFGYSWKNIQERYGSLSGQLHMIELEKGHSGLGLSLAGNKDRTRMSVFIVGIDPTGAAGRDGRLQVADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNEDAVNQMAVCPGNAADPLPSISESPQNKEVEPSVTTSAALDLSSLTNVYHLELPKDQGGLGIAISEEDTLNGLVIKSITEHGEAAKDGRLKAGDQILAVDDEVVAGCPVEKFISLLKTAKATVKLTVRAENPACQAVPSAASSASGERKESAQSPAVPTLDPDSIPNTSRSSTPAVFASDPATCPIIPGCETTIEISKGQTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEDVCDTFTIDLQKRPGKGLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVTLEVGRIKAGPFHSERRPSQSSQVSDSSLSSFTLPLSGINASESLESNSKKNALASEIQGLRTVEIKKGPSDSLGISIAGGVGSPLGDVPIFIAMMHPNGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLMKNAPGSIEMQVVAGGDVSVVTGHQQELANPCLAFTGLTSSSIFPDDLGPPQCKTITLDRGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLVVLS", "length": 1994, "header": "tr|A0A9J7FC50-1|A0A8C2N0K3_CRIGR Computationally mapped isoform of Multiple PDZ domain protein OS=Cricetulus griseus OX=10029 GN=Mpdz PE=4 SV=1 CANONICAL=A0A8C2N0K3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FDP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0K3/entry#A0A9J7FDP7-1", "sequence": { "sequence": "MLETIDKNRALQAAERLQNKLKERGDVANEDKLSLLKSVLQSPLFSQILNLQTSLQQLKDQVNIATLATTNADPAHTPQLSSSSIPTLQSESLLLSPNNGNLEPLSGSGAPPVTVGKPAFDELDQLIKNMAQGRHVEIFELLKPPCGGLGFSVVGLRSENRGELGIFVQEIQEGSVAYRDGRLKEMDQILAINGQFLDQTITHQQAISILQKAKDTVQLVVARGSLPQVSSPRISRSPSAASTVSAHSNPIHWQHVETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVLRQCGNRVKLVIARGAVEETAAPSSLGITLSSSPVSTSEMRVDASTQKSEESEMFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKCSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVRLTLMRKGARQEAELTSREDAAKDVDVPPGDATVSKENYEKDEESLSLRRNISILPIEEEGYPLLSTQLEEAEDVQQEAALLTKWQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNILKELPIDVTMVCCRRTVPPTASSELDGLDISDLELTEKPHIDLGEFIGSSETEDPVLAIPDVDQNAEEIQTPVAMWEAGIQSIELEKGSRGLGFSILDYQDPIDPTSTVIVIRSLVPGGIAEKDGRLVPGDRLMFVNDINLENSSLEEAVEALKGAPSGMVRIGVAKPLPLSPEEGYVSAKEDMFLCPPHSCKEPGLPDKALFRADLALIDAPDAESVAESRFDSPFSPDNDSVYSTQASVLSLQDSACSDGMNYGPSLPSSPPKDVTGSSDLVLGLHLSLEELYTQNLLPRQQAASPLPDRSMAATSGSAIGDYPPANAVEQKYECANTVAWTHSQLPSGLCATELAPALPTAAQKYLTEESSLASDAESVPLQSMSQETFERTVTIAKGSSSLGMTVSANKDGLGVIVRSIIHGGAISRDGRIAVGDCILSINEESTISLTNAQARAMLRRHSLIGPDIKITYVPAEHLEEFRISFGQQSGGIMALDIFSSYTGRDIPELPEREEGEGEESELQNAGYSSWSQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIIEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKFPLPSLPHNLYPKYSFSSTNPFADSLQLATDKAPNQSASDSEKAPMCDVPPSSPSGFSEMGSDCAQPSTITVSEDADKEDEFGYSWKNIQERYGSLSGQLHMIELEKGHSGLGLSLAGNKDRTRMSVFIVGIDPTGAAGRDGRLQVADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNEDAVNQMAVCPGNAADPLPSISESPQNKEVEPSVTTSAALDLSSLTNVYHLELPKDQGGLGIAISEEDTLNGLVIKSITEHGEAAKDGRLKAGDQILAVDDEVVAGCPVEKFISLLKTAKATVKLTVRAENPACQAVPSAASSASGERKESAQSPAVPTLDPDSIPNTSRSSTPAVFASDPATCPIIPGCETTIEISKGQTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEDVCDTFTIDLQKRPGKGLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVTLEVGRIKAGPFHSERRPSQSSQVSDSSLSSFTLPLSGINASESLESNSKKNALASEIQGLRTVEIKKGPSDSLGISIAGGVGSPLGDVPIFIAMMHPNGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLMKNAPGSIEMQVVAGGDVSVVTGHQQELANPCLAFTGLTSSSIFPDDLGPPQCKTITLDRGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLVVLS", "length": 2061, "header": "tr|A0A9J7FDP7-1|A0A8C2N0K3_CRIGR Computationally mapped isoform of Multiple PDZ domain protein OS=Cricetulus griseus OX=10029 GN=Mpdz PE=4 SV=1 CANONICAL=A0A8C2N0K3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GTY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0K3/entry#A0A9J7GTY4-1", "sequence": { "sequence": "MAQGRHVEIFELLKPPCGGLGFSVVGLRSENRGELGIFVQEIQEGSVAYRDGRLKEMDQILAINGQFLDQTITHQQAISILQKAKDTVQLVVARGSLPQVSSPRISRSPSAASTVSAHSNPIHWQHVETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVLRQCGNRVKLVIARGAVEETAAPSSLGITLSSSPVSTSEMRVDASTQKSEESEMFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKCSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVRLTLMRKGARQEAELTSREDAAKDVDVPPGDATVSKENYEKDEESLSLRRNISILPIEEEGYPLLSTQLEEAEDVQQEAALLTKWQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNILKELPIDVTMVCCRRTVPPTASSELDGLDISDLELTEKPHIDLGEFIGSSETEDPVLAIPDVDQNAEEIQTPVAMWEAGIQSIELEKGSRGLGFSILDYQDPIDPTSTVIVIRSLVPGGIAEKDGRLVPGDRLMFVNDINLENSSLEEAVEALKGAPSGMVRIGVAKPLPLSPEEGYVSAKEDMFLCPPHSCKEPGLPDKALFRADLALIDAPDAESVAESRFDSPFSPDNDSVYSTQASVLSLQDSACSDGMNYGPSLPSSPPKDVTGSSDLVLGLHLSLEELYTQNLLPRQQAASPLPDRSMAATSGSAIGDYPPANAVEQKYECANTVAWTHSQLPSGLCATELAPALPTAAQKGSEYLTEESSLASDAESVPLQSMSQETFERTVTIAKGSSSLGMTVSANKDGLGVIVRSIIHGGAISRDGRIAVGDCILSINEESTISLTNAQARAMLRRHSLIGPDIKITYVPAEHLEEFRISFGQQSGGIMALDIFSSYTGRDIPELPEREEGEGEESELQNAGYSSWSQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIIEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKFPLPSLPHNLYPKYSFSSTNPFADSLQLATDKAPNQSASDSEKAPMCDVPPSSPSGFSEMGSDCAQPSTITVSEDADKEDEFGYSWKNIQERYGSLSGQLHMIELEKGHSGLGLSLAGNKDRTRMSVFIVGIDPTGAAGRDGRLQVADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNEDAVNQMAVCPGNAADPLPSISESPQNKEVEPSVTTSAALDLSSLTNVYHLELPKDQGGLGIAISEEDTLNGLVIKSITEHGEAAKDGRLKAGDQILAVDDEVVAGCPVEKFISLLKTAKATVKLTVRAENPACQAVPSAASSASGERKESAQSPAVPTLDPDSIPNTSRSSTPAVFASDPATCPIIPGCETTIEISKGQTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEDVCDTFTIDLQKRPGKGLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVTLEVGRIKAGPFHSERRPSQSSQVSDSSLSSFTLPLSGINASESLESNSKKNALASEIQGLRTVEIKKGPSDSLGISIAGGVGSPLGDVPIFIAMMHPNGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLMKNAPGSIEMQVVAGGDVSVVTGHQQELANPCLAFTGLTSSSIFPDDLGPPQCKTITLDRGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLVVLS", "length": 1935, "header": "tr|A0A9J7GTY4-1|A0A9J7GTY4_CRIGR Computationally mapped isoform of Multiple PDZ domain protein OS=Cricetulus griseus OX=10029 GN=Mpdz PE=4 SV=1 CANONICAL=A0A8C2N0K3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J918-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0K3/entry#A0A9J7J918-1", "sequence": { "sequence": "MLETIDKNRALQAAERLQNKLKERGDVANEDKLSLLKSVLQSPLFSQILNLQTSLQQLKDQVNIATLATTNADPAHTPQLSSSSIPTLQSESLLLSPNNGNLEPLSGSGAPPVTVGKPAFDELDQLIKNMAQGRHVEIFELLKPPCGGLGFSVVGLRSENRGELGIFVQEIQEGSVAYRDGRLKEMDQILAINGQFLDQTITHQQAISILQKAKDTVQLVVARGSLPQVSSPRISRSPSAASTVSAHSNPIHWQHVETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVLRQCGNRVKLVIARGAVEETAAPSSLGITLSSSPVSTSEMRVDASTQKSEESEMFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKCSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVRLTLMRKGARQEAELTSREDAAKDVDVPPGDATVSKENYEKDEESLSLRRNISILPIEEEGYPLLSTQLEEAEDVQQEAALLTKWQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNILKELPIDVTMVCCRRTVPPTASSELDGLDISDLELTEKPHIDLGEFIGSSETEDPVLAIPDVDQNAEEIQTPVAMWEAGIQSIELEKGSRGLGFSILDYQDPIDPTSTVIVIRSLVPGGIAEKDGRLVPGDRLMFVNDINLENSSLEEAVEALKGAPSGMVRIGVAKPLPLSPEEGYVSAKEDMFLCPPHSCKEPGLPDKALFRADLALIDAPDAESVAESRFDSPFSPDNDSVYSTQASVLSLQDSACSDGMNYGPSLPSSPPKDVTGSSDLVLGLHLSLEELYTQNLLPRQQAASPLPDRSMAATSGSAIGDYPPANAVEQKYECANTVAWTHSQLPSGLCATELAPALPTAAQKGSEYLTEESSLASDAESVPLQSMSQETFERTVTIAKGSSSLGMTVSANKDGLGVIVRSIIHGGAISRDGRIAVGDCILSINEESTISLTNAQARAMLRRHSLIGPDIKITYVPAEHLEEFRISFGQQSGGIMALDIFSSYTGRDIPELPEREEGEGEESELQNAGYSSWSQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIIEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRAPNQSASDSEKAPMCDVPPSSPSGFSEMGSDCAQPSTITVSEDADKEDEFGYSWKNIQERYGSLSGQLHMIELEKGHSGLGLSLAGNKDRTRMSVFIVGIDPTGAAGRDGRLQVADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNEDAVNQMAVCPGNAADPLPSISESPQNKEVEPSVTTSAALDLSSLTNVYHLELPKDQGGLGIAISEEDTLNGLVIKSITEHGEAAKDGRLKAGDQILAVDDEVVAGCPVEKFISLLKTAKATVKLTVRAENPACQAVPSAASSASGERKESAQSPAVPTLDPDSIPNTSRSSTPAVFASDPATCPIIPGCETTIEISKGQTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEDVCDTFTIDLQKRPGKGLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVTLEVGRIKAGPFHSERRPSQSSQVSDSSLSSFTLPLSGINASESLESNSKKNALASEIQGLRTVEIKKGPSDSLGISIAGGVGSPLGDVPIFIAMMHPNGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLMKNAPGSIEMQVVAGGDVSVVTGHQQELANPCLAFTGLTSSSIFPDDLGPPQCKTITLDRGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLVVLS", "length": 2031, "header": "tr|A0A9J7J918-1|A0A9J7J918_CRIGR Computationally mapped isoform of Multiple PDZ domain protein OS=Cricetulus griseus OX=10029 GN=Mpdz PE=4 SV=1 CANONICAL=A0A8C2N0K3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JEI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0K3/entry#A0A9J7JEI2-1", "sequence": { "sequence": "MLETIDKNRALQAAERLQNKLKERGDVANEDKLSLLKSVLQSPLFSQILNLQTSLQQLKDQVNIATLATTNADPAHTPQLSSSSIPTLQSESLLLSPNNGNLEPLSGSGAPPVTVGKPAFDELDQLIKNMAQGRHVEIFELLKPPCGGLGFSVVGLRSENRGELGIFVQEIQEGSVAYRDGRLKEMDQILAINGQFLDQTITHQQAISILQKAKDTVQLVVARGSLPQVSSPRISRSPSAASTVSAHSNPIHWQHVETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVLRQCGNRVKLVIARGAVEETAAPSSLGITLSSSPVSTSEMRVDASTQKSEESEMFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKCSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVRLTLMRKGARQEAELTSREDAAKDVDVPPGDATVSKENYEKDEESLSLRRNISILPIEEEGYPLLSTQLEEAEDVQQEAALLTKWQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNILKELPIDVTMVCCRRTVPPTASSELDGLDISDLELTEKPHIDLGEFIGSSETEDPVLAIPDVDQNAEEIQTPVAMWEAGIQSIELEKGSRGLGFSILDYQDPIDPTSTVIVIRSLVPGGIAEKDGRLVPGDRLMFVNDINLENSSLEEAVEALKGAPSGMVRIGVAKPLPIDAPDAESVAESRFDSPFSPDNDSVYSTQASVLSLQDSACSDGMNYGPSLPSSPPKDVTGSSDLVLGLHLSLEELYTQNLLPRQQAASPLPDRSMAATSGSAIGDYPPANAVEQKYECANTVAWTHSQLPSGLCATELAPALPTAAQKGSEYLTEESSLASDAESVPLQSMSQETFERTVTIAKGSSSLGMTVSANKDGLGVIVRSIIHGGAISRDGRIAVGDCILSINEESTISLTNAQARAMLRRHSLIGPDIKITYVPAEHLEEFRISFGQQSGGIMALDIFSSYTGRDIPELPEREEGEGEESELQNAGYSSWSQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIIEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKFPLPSLPHNLYPKYSFSSTNPFADSLQLATDKAPNQSASDSEKAPMCDVPPSSPSGFSEMGSDCAQPSTITVSEDADKEDEFGYSWKNIQERYGSLSGQLHMIELEKGHSGLGLSLAGNKDRTRMSVFIVGIDPTGAAGRDGRLQVADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNEDAVNQMAVCPGNAADPLPSISESPQNKEVEPSVTTSAALDLSSLTNVYHLELPKDQGGLGIAISEEDTLNGLVIKSITEHGEAAKDGRLKAGDQILAVDDEVVAGCPVEKFISLLKTAKATVKLTVRAENPACQAVPSAASSASGERKESAQSPAVPTLDPDSIPNTSRSSTPAVFASDPATCPIIPGCETTIEISKGQTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEDVCDTFTIDLQKRPGKGLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVTLEVGRIKAGPFHSERRPSQSSQVSDSSLSSFTLPLSGINASESLESNSKKNALASEIQGLRTVEIKKGPSDSLGISIAGGVGSPLGDVPIFIAMMHPNGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLMKNAPGSIEMQVVAGGDVSVVTGHQQELANPCLAFTGLTSSSIFPDDLGPPQCKTITLDRGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLVVLS", "length": 2025, "header": "tr|A0A9J7JEI2-1|A0A9J7JEI2_CRIGR Computationally mapped isoform of Multiple PDZ domain protein OS=Cricetulus griseus OX=10029 GN=Mpdz PE=4 SV=1 CANONICAL=A0A8C2N0K3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JEQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0K3/entry#A0A9J7JEQ0-1", "sequence": { "sequence": "MLETIDKNRALQAAERLQNKLKERGDVANEDKLSLLKSVLQSPLFSQILNLQTSLQQLKDQVNIATLATTNADPAHTPQLSSSSIPTLQSESLLLSPNNGNLEPLSGSGAPPVTVGKPAFDELDQLIKNMAQGRHVEIFELLKPPCGGLGFSVVGLRSENRGELGIFVQEIQEGSVAYRDGRLKEMDQILAINGQFLDQTITHQQAISILQKAKDTVQLVVARGSLPQVSSPRISRSPSAASTVSAHSNPIHWQHVETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVLRQCGNRVKLVIARGAVEETAAPSSLGITLSSSPVSTSEMRVDASTQKSEESEMFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKCSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVRLTLMRKGARQEAELTSREDAAKDVDVPPGDATVSKENYEKDEESLSLRRNISILPIEEEGYPLLSTQLEEAEDVQQEAALLTKWQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNILKELPIDVTMVCCRRTVPPTASSELDGLDISDLELTEKPHIDLGEFIGSSETEDPVLAIPDVDQNAEEIQTPVAMWEAGIQSIELEKGSRGLGFSILDYQDPIDPTSTVIVIRSLVPGGIAEKDGRLVPGDRLMFVNDINLENSSLEEAVEALKGAPSGMVRIGVAKPLPLSPEEGYVSAKEDMFLCPPHSCKEPGLPDKALFRADLALIDAPDAESVAESRFDSPFSPDNDSVYSTQASVLSLQDSACSDGMNYGPSLPSSPPKDVTGSSDLVLGLHLSLEELYTQNLLPRQQAASPLPDRSMAATSGSAIGDYPPANAVEQKYECANTVAWTHSQLPSGLCATELAPALPTAAQKYLTEESSLASDAESVPLQSMSQETFERTVTIAKGSSSLGMTVSANKDGLGVIVRSIIHGGAISRDGRIAVGDCILSINEESTISLTNAQARAMLRRHSLIGPDIKITYVPAEHLEEFRISFGQQSGGIMALDIFSSYTGRDIPELPEREEGEGEESELQNAGYSSWSQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIIEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRAPNQSASDSEKAPMCDVPPSSPSGFSEMGSDCAQPSTITVSEDADKEDEFGYSWKNIQERYGSLSGQLHMIELEKGHSGLGLSLAGNKDRTRMSVFIVGIDPTGAAGRDGRLQVADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNEDAVNQMAVCPGNAADPLPSISESPQNKEVEPSVTTSAALDLSSLTNVYHLELPKDQGGLGIAISEEDTLNGLVIKSITEHGEAAKDGRLKAGDQILAVDDEVVAGCPVEKFISLLKTAKATVKLTVRAENPACQAVPSAASSASGERKESAQSPAVPTLDPDSIPNTSRSSTPAVFASDPATCPIIPGCETTIEISKGQTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEDVCDTFTIDLQKRPGKGLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVTLEVGRIKAGPFHSERRPSQSSQVSDSSLSSFTLPLSGINASESLESNSKKNALASEIQGLRTVEIKKGPSDSLGISIAGGVGSPLGDVPIFIAMMHPNGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLMKNAPGSIEMQVVAGGDVSVVTGHQQELANPCLAFTGLTSSSIFPDDLGPPQCKTITLDRGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLVVLS", "length": 2028, "header": "tr|A0A9J7JEQ0-1|A0A9J7JEQ0_CRIGR Computationally mapped isoform of Multiple PDZ domain protein OS=Cricetulus griseus OX=10029 GN=Mpdz PE=4 SV=1 CANONICAL=A0A8C2N0K3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 114, "start_aa": "Thr", "end_pos": 114, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr114", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": 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Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613885.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502281", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502281" } ] }, { "annotation": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. 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This record is derived from a genomic sequence (NW_003614645.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509126", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509126" } ] }, { "annotation": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0L3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L3#function" }, { "database": "UniProtKB", "id": "ARBA00002002", "url": "https://www.uniprot.org/uniprotkb/ARBA00002002#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0L3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gnb4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L3", "locus": {} } ], "crossref": [ { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757050", "url": "https://www.ncbi.nlm.nih.gov/gene/100757050", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757050", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757050", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GDTNCAL", "url": "https://omabrowser.org/oma/group/GDTNCAL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N0L3", "url": "https://www.orthodb.org/?gene=A0A8C2N0L3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19850", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19850", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509126", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509126", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N0L3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGRIQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQIITSSGDTTCALWDIETGQQTTTFAGHSGDVMSLSLSPDLKTFVSGACDASSKLWDVRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN", "length": 340, "header": "tr|A0A8C2N0L3-1|A0A8C2N0L3_CRIGR Isoform 1 of Guanine nucleotide-binding protein subunit beta-4 OS=Cricetulus griseus OX=10029 GN=Gnb4 PE=3 SV=1 CANONICAL=A0A8C2N0L3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N0L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L3/entry#A0A8C2N0L3-1", "sequence": { "sequence": "MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGRIQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQIITSSGDTTCALWDIETGQQTTTFAGHSGDVMSLSLSPDLKTFVSGACDASSKLWDVRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN", "length": 340, "header": "tr|A0A8C2N0L3-1|A0A8C2N0L3_CRIGR Isoform 1 of Guanine nucleotide-binding protein subunit beta-4 OS=Cricetulus griseus OX=10029 GN=Gnb4 PE=3 SV=1 CANONICAL=A0A8C2N0L3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266050", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266050" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0L6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cog7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L6", "locus": {} } ], "crossref": [ { "id": "100754278", "url": "https://www.ncbi.nlm.nih.gov/gene/100754278", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019335", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019335", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754278", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754278", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N0L6", "url": "https://www.orthodb.org/?gene=A0A8C2N0L6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21443", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21443", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21443:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21443:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027266050", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266050", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N0L6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFSKFLADDFDVKDWINAAFRAGPKDGAAGKADGHAATLVMKLQLFIQEVNHSVEETSLQALQNMPKVLRDVEALKQEASFLKEQMILVKEDIKKFEQDTSQSMQVLVEIDQVKSRMQLAAESLQEADKWSTLSADIEETFKTQDVAVISAKLTGMQNSLMMLVDTPDYSEKCVHLEALKNRLEALASPQIVAAFTSQSVDQSKVFVKVFTEIDRMPQLLAYYYKCHKVQLLAAWQELCQSDLPLDRQLTGLYDALLGAWHTQTQWATQVFKNPHEVVTVLLIQTLGALVPSLPMCLSAGVERAGPELELTRLLEFYDTTAHFAKGLEMALLPHLQDHNLVKVVELVDAVYGPYKPYQLKYGDMEENNLLIQISAVPLEHGEVIDCVQELSHSVHKLFGLASAAVDRCARFTNGLGTCGLLTALKSLFAKYVSHFTNALQSVRKKCRLDDIPPNSLFQEDWTAFQNSVRIIATCGELLRQCGDFEQQLANRILSTAGKYLSDSYSPRSLAGFQDSILTDKKSPAKNPWQEYNYLQKDNPAEYASLMEILYTLKEKGSSNHNLLSASRTALTRLNQQAHQLAFDSVFLRIKQQLLLVSRMDSWNTAGIGETLTDDLPAFSLTPLEYISNIGQYIMSLPLNLEPFVTQEDSALELALHAGKLPFPPEQGDELPELDNMADNWLGSIARATMQTYCDVILQISEVTPHSTKQLATDIDYLINVMDALGLQPSRTLQNIVTLLKAKPEEYRQVSKGLPRRLAATVATMRGVNY", "length": 770, "header": "tr|A0A8C2N0L6-1|A0A8C2N0L6_CRIGR Isoform 1 of Conserved oligomeric Golgi complex subunit 7 OS=Cricetulus griseus OX=10029 GN=Cog7 PE=3 SV=1 CANONICAL=A0A8C2N0L6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N0L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L6/entry#A0A8C2N0L6-1", "sequence": { "sequence": "MDFSKFLADDFDVKDWINAAFRAGPKDGAAGKADGHAATLVMKLQLFIQEVNHSVEETSLQALQNMPKVLRDVEALKQEASFLKEQMILVKEDIKKFEQDTSQSMQVLVEIDQVKSRMQLAAESLQEADKWSTLSADIEETFKTQDVAVISAKLTGMQNSLMMLVDTPDYSEKCVHLEALKNRLEALASPQIVAAFTSQSVDQSKVFVKVFTEIDRMPQLLAYYYKCHKVQLLAAWQELCQSDLPLDRQLTGLYDALLGAWHTQTQWATQVFKNPHEVVTVLLIQTLGALVPSLPMCLSAGVERAGPELELTRLLEFYDTTAHFAKGLEMALLPHLQDHNLVKVVELVDAVYGPYKPYQLKYGDMEENNLLIQISAVPLEHGEVIDCVQELSHSVHKLFGLASAAVDRCARFTNGLGTCGLLTALKSLFAKYVSHFTNALQSVRKKCRLDDIPPNSLFQEDWTAFQNSVRIIATCGELLRQCGDFEQQLANRILSTAGKYLSDSYSPRSLAGFQDSILTDKKSPAKNPWQEYNYLQKDNPAEYASLMEILYTLKEKGSSNHNLLSASRTALTRLNQQAHQLAFDSVFLRIKQQLLLVSRMDSWNTAGIGETLTDDLPAFSLTPLEYISNIGQYIMSLPLNLEPFVTQEDSALELALHAGKLPFPPEQGDELPELDNMADNWLGSIARATMQTYCDVILQISEVTPHSTKQLATDIDYLINVMDALGLQPSRTLQNIVTLLKAKPEEYRQVSKGLPRRLAATVATMRGVNY", "length": 770, "header": "tr|A0A8C2N0L6-1|A0A8C2N0L6_CRIGR Isoform 1 of Conserved oligomeric Golgi complex subunit 7 OS=Cricetulus griseus OX=10029 GN=Cog7 PE=3 SV=1 CANONICAL=A0A8C2N0L6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0L6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754278", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754278", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0L6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L6" } ], "pmid": "" }, { "name": "Golgi transport complex", "id": "GO:0017119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017119", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0L6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0L6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L6" } ], "pmid": "" }, { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0L6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L6" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0L6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L6" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0L6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L6" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0L6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L6" } ], "pmid": "" }, { "name": "protein localization to Golgi apparatus", "id": "GO:0034067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034067", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0L6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L6" } ], "pmid": "" }, { "name": "retrograde transport, vesicle recycling within Golgi", "id": "GO:0000301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000301", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0L6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N0N1-1", "uniprot_ac": "A0A8C2N0N1", "uniprot_id": "A0A8C2N0N1_CRIGR", "mass": { "chemical_mass": 65997.0, "monoisotopic_mass": 65997.0 }, "refseq": { "ac": "XP_035300631", "name": "apoptosis-inducing factor 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300631" }, "gene_names": [ { "name": "Aifm3", "type": "recommended", "evidence": [ { "id": "A0A8C2N0N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1" } ] }, { "name": "Aifm3", "type": "synonym", "evidence": [ { "id": "XP_035300631", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300631" } ] } ], "protein_names": [ { "name": "Apoptosis-inducing factor 3", "type": "recommended", "evidence": [ { "id": "A0A8C2N0N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1/entry#names_and_taxonomy" } ] }, { "name": "Apoptosis-inducing factor-like protein", "type": "synonym", "evidence": [ { "id": "A0A8C2N0N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1/entry#names_and_taxonomy" } ] }, { "name": "apoptosis-inducing factor 3", "type": "synonym", "evidence": [ { "id": "XP_035300631", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300631" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035300631", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300631" } ] }, { "annotation": "Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1#function" }, { "database": "UniProtKB", "id": "ARBA00058975", "url": "https://www.uniprot.org/uniprotkb/ARBA00058975#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Aifm3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1", "locus": {} } ], "crossref": [ { "id": "cd03478", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03478", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752310", "url": "https://www.ncbi.nlm.nih.gov/gene/100752310", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050446", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050446", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752310", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752310", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PRCTHYG", "url": "https://omabrowser.org/oma/group/PRCTHYG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N0N1", "url": "https://www.orthodb.org/?gene=A0A8C2N0N1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43557", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43557", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43557:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43557:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00355", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00355", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07992", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07992", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035300631", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300631", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N0N1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHAEERLPTPQPYPSPQDCVEATVCHVKDLENGQMREVELGWGKVLLLKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVTVRASKQALQLQRRTKVMAKCISPSAGHSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRAKLSKSLDAQPEQLALRPKEFFRAYGIEMLTEAQVVTVDVRNKKVVFKDGFKLEYSKLLLAPGSSPKTLNCKGKDVENVFTIRTPEDANHVLRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVLELRAQEGKLQEVVLKSSKVLRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNIPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEINTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRTIRKREVETGDMSWLTGRGS", "length": 598, "header": "tr|A0A8C2N0N1-1|A0A8C2N0N1_CRIGR Isoform 1 of Apoptosis-inducing factor 3 OS=Cricetulus griseus OX=10029 GN=Aifm3 PE=3 SV=1 CANONICAL=A0A8C2N0N1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N0N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1/entry#A0A8C2N0N1-1", "sequence": { "sequence": "MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHAEERLPTPQPYPSPQDCVEATVCHVKDLENGQMREVELGWGKVLLLKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVTVRASKQALQLQRRTKVMAKCISPSAGHSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRAKLSKSLDAQPEQLALRPKEFFRAYGIEMLTEAQVVTVDVRNKKVVFKDGFKLEYSKLLLAPGSSPKTLNCKGKDVENVFTIRTPEDANHVLRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVLELRAQEGKLQEVVLKSSKVLRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNIPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEINTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRTIRKREVETGDMSWLTGRGS", "length": 598, "header": "tr|A0A8C2N0N1-1|A0A8C2N0N1_CRIGR Isoform 1 of Apoptosis-inducing factor 3 OS=Cricetulus griseus OX=10029 GN=Aifm3 PE=3 SV=1 CANONICAL=A0A8C2N0N1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752310", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752310", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LZF1-1", "protein_name": "Apoptosis-inducing factor 3", "gene_name": "AIFM3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGGCFSKPKPVELKIEVVLPEKDRGKEELSTGSRGSPRAYQGNGAARHFHADERLPTAHPYPGAQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGELHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNVSTGDLEDFPGLDSLHKFQVKIEKEKVYIRASKQALQLQRRTKVMATCISPSAGYSGSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSLDAQPEQLALRPKEFFRAHGIEVLTEAQVVTVDVRNKKAVFKDGFKLEYSKLLLAPGSSPKTLSCKGKDVENVFTIRTPEDANRVVRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVEVEETPFRRFLGERVGHTLMKMFENNRVKFYMQTEVSELRAQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGISLDSRGFIPVNKMMQTNIPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEISTVPFLWTAMFGKSLRYAGYGEGFDDVIIQGDLDELKFVAFYTKGDEVISVASMNYDPIVSKVAEVLASGRTIRKREVELFVLHSKTGDMSWLTGKGS", "length": 605 }, "evidence": [ { "id": "A0A8C2N0N1", "url": "https://omabrowser.org/oma/group/A0A8C2N0N1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A4X1UXM0-1", "protein_name": "Apoptosis-inducing factor 3", "gene_name": "AIFM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGGCFSKPKPVELKIEVVLPEKDRKEELSASGKGSPRAYQGNGTARHFHAEERLPAPHPYPGAQDFMEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKVMATCISPSAGHSGSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSLDTQPEQLALRPKEFFRAHGIEVLTEAQVVTVDVRNKKAVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRLLGERVGRALMKMFENNRVKFYMQTEVLELRAQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEISTVPYLWTAMFGKSLRYAGYGEGFDDVVIQGDLHELKFVAFYTKGDEVISVASMNYDPIVSKVAEVLASGRSIRKREVELFLLHSKTGDMSWLTGKGS", "length": 604 }, "evidence": [ { "id": "A0A8C2N0N1", "url": "https://omabrowser.org/oma/group/A0A8C2N0N1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M2BC75-1", "protein_name": "Apoptosis-inducing factor 3 isoform X1", "gene_name": "aifm3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGGCLSKPKPVEVKVELTLLDKEKEVDLMSPNGKASPFSECRPNGSLGHCSDEDSMTLRPQRKNRDYIEASVCHIKDLENGQMREVDLGAGRALLIKEHGEFFAMGHKCPHYGAPLVKGVLSKGHVRCPWHGACFNIATGDIEDFPGLDSLPTFQVRVEKEKVIIRANKQALQTQRRSKVMSKCSAVINSSTGFSHVLIIGSGPAGLVCAETLRQEGFTDRIVICTTDKHLPYDRPKLSKSLESTAEQLQLRSSDFFQMHDIEVLLEKEVVSVDVKTHTVTFRDGFKMEYRKLFIATGSRPKPLSYKGKDVGNVFHLRTPEDANSIVTLASSKNAVIIGTSFIGMEVAAALTDKAHSVSVIGIEAVPFRKALGEKVGKALMKLFEANRVKFYMLNEVWEMRGHNGQLKEVVLKSGKVLRADVCVIGIGSSPATAFLKQSGVHIDSKGFIPVNKTMQTNIDGVFAGGDVVTFPLALRSNKKVNIPHWQMAHVHGRLAALGIMGKASDIKTVPYFWTAMFGKSIRYAGYGDGFDDVVIQGDLDELKFVAFYTKSEEVVAVASMNYDPIVSRVAEVFGSGKTIRKRDVETGDMSWLIVKGSQ", "length": 599 }, "evidence": [ { "id": "A0A8C2N0N1", "url": "https://omabrowser.org/oma/group/A0A8C2N0N1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZF03-1", "protein_name": "Apoptosis-inducing factor 3", "gene_name": "Aifm3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRGYQGNGTARHFHAEERLPTPQPYPSPQDCVEATVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNIGTGDLEDFPGLDSLHKFQVKIEKEKVTVRASKQALQLQRRTKVMAKCISPSAGHSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRAKLSKSLDAQPEQLALRPKEFFRAYGIEMLTEAQVVTVDVRNKKVVFKDGFKLEYSKLLLAPGSSPKTLTCKGKDIENVFTIRTPEDANRVLRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRAQEGKLQEVVLKSSKVLRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNIPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEINTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFMLHSKTGDMSWLTGKGS", "length": 604 }, "evidence": [ { "id": "A0A8C2N0N1", "url": "https://omabrowser.org/oma/group/A0A8C2N0N1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3TY86-1", "protein_name": "Apoptosis-inducing factor 3", "gene_name": "Aifm3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRGYQGNGTARHFHAEERLPTPQPYPSPQDCVEATVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVTIRASKQALQLQRRTKVMAKCISPSAGHSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRAKLSKSLDAQPEQLALRPKEFFRAYGIEMLTEAQVVTVDVRNKKVVFKDGFKLEYSKLLLAPGSSPKTLTCKGKDVENVFTIRTPEDANRVLRLARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRAQEGKLQEVVLKSSKVLRADVCVLGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEINTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKSDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFMLHSKTGDMSWLTGKGS", "length": 605 }, "evidence": [ { "id": "A0A8C2N0N1", "url": "https://omabrowser.org/oma/group/A0A8C2N0N1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96NN9-1", "protein_name": "Apoptosis-inducing factor 3", "gene_name": "AIFM3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHTEERLSTPHPYPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKVMAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFVLHSKTGDMSWLTGKGS", "length": 605 }, "evidence": [ { "id": "A0A8C2N0N1", "url": "https://omabrowser.org/oma/group/A0A8C2N0N1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9LFA3-1", "protein_name": "Monodehydroascorbate reductase 1, peroxisomal", "gene_name": "MDAR1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAEKSFKYIILGGGVSAGYAAKEFANQGVQPGELAVISKEAVAPYERPALSKGYLFPEGAARLPGFHCCVGSGGEKLLPESYKQKGIELILSTEIVKADLSAKSLVSATGDVFKYQTLIIATGSTVLRLTDFGVKGADSKNILYLREIDDADKLVEAIKAKKGGKAVVVGGGYIGLELSAVLRINNLDVTMVFPEPWCMPRLFTADIAAFYETYYTNKGVKIIKGTVASGFTAQPNGEVKEVQLKDGRTLEADIVIVGVGAKPLTSLFKGQVEEDKGGIKTDAFFKTSVPDVYAVGDVATFPLKMYGDVRRVEHVDHSRKSAEQAVKAIKAAEGGAAVEEYDYLPFFYSRSFDLSWQFYGDNVGDSVLFGDSNPSNPKPRFGAYWVQGGKVVGAFMEGGSGDENKALAKVAKARPSAESLDELVKQGISFAAKI", "length": 434 }, "evidence": [ { "id": "A0A8C2N0N1", "url": "https://omabrowser.org/oma/group/A0A8C2N0N1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on NAD(P)H", "id": "GO:0016651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016651", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "execution phase of apoptosis", "id": "GO:0097194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097194", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N0N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N1" }, { "id": "PS51296", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51296" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rieske", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 165, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N0N7-1", "uniprot_ac": "A0A8C2N0N7", "uniprot_id": "A0A8C2N0N7_CRIGR", "mass": { "chemical_mass": 35190.0, "monoisotopic_mass": 35190.0 }, "refseq": { "ac": "XP_027275491", "name": "NF-kappa-B inhibitor alpha isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275491" }, "gene_names": [ { "name": "Nfkbia", "type": "recommended", "evidence": [ { "id": "A0A8C2N0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N7" } ] }, { "name": "Nfkbia", "type": "synonym", "evidence": [ { "id": "XP_027275491", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275491" } ] } ], "protein_names": [ { "name": "NF-kappa-B inhibitor alpha", "type": "recommended", "evidence": [ { "id": "A0A8C2N0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N7/entry#names_and_taxonomy" } ] }, { "name": "I-kappa-B-alpha", "type": "synonym", "evidence": [ { "id": "A0A8C2N0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N7/entry#names_and_taxonomy" } ] }, { "name": "NF-kappa-B inhibitor alpha isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027275491", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275491" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275491", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275491" } ] }, { "annotation": "Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL (RELA/p65 and NFKB1/p50) dimers in the cytoplasm by masking their nuclear localization signals. On cellular stimulation by immune and pro-inflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N7#function" }, { "database": "UniProtKB", "id": "ARBA00045368", "url": "https://www.uniprot.org/uniprotkb/ARBA00045368#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nfkbia", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N7", "locus": {} } ], "crossref": [ { "id": "100754153", "url": "https://www.ncbi.nlm.nih.gov/gene/100754153", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754153", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754153", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N0N7", "url": "https://www.orthodb.org/?gene=A0A8C2N0N7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46680", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46680", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46680:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46680:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027275491", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275491", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N0N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFQPAGHGQDWAMEGPRDALKKERLVDDRHDSGLDSMKDEEYEQMVKELQEIRLQPQEAPLAAEPWKQQLTEDGDSFLHLAIIHEEKTLTMEVIRQVKGDLAFLNFQNNLQQTPLHLAVITNQPGIAEALLEAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQTCTPQHLHSILQATNYNGHTCLHLASIHGYLGIVEHLVSLGADVNAQEPCNGRTALHLAVDLQNPELVSLLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTRENLQMLPESEDEESYDTESEFTEDELPYDDCVFGGQRLTL", "length": 314, "header": "tr|A0A8C2N0N7-1|A0A8C2N0N7_CRIGR Isoform 1 of NF-kappa-B inhibitor alpha OS=Cricetulus griseus OX=10029 GN=Nfkbia PE=3 SV=1 CANONICAL=A0A8C2N0N7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N0N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N7/entry#A0A8C2N0N7-1", "sequence": { "sequence": "MFQPAGHGQDWAMEGPRDALKKERLVDDRHDSGLDSMKDEEYEQMVKELQEIRLQPQEAPLAAEPWKQQLTEDGDSFLHLAIIHEEKTLTMEVIRQVKGDLAFLNFQNNLQQTPLHLAVITNQPGIAEALLEAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQTCTPQHLHSILQATNYNGHTCLHLASIHGYLGIVEHLVSLGADVNAQEPCNGRTALHLAVDLQNPELVSLLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTRENLQMLPESEDEESYDTESEFTEDELPYDDCVFGGQRLTL", "length": 314, "header": "tr|A0A8C2N0N7-1|A0A8C2N0N7_CRIGR Isoform 1 of NF-kappa-B inhibitor alpha OS=Cricetulus griseus OX=10029 GN=Nfkbia PE=3 SV=1 CANONICAL=A0A8C2N0N7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754153", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754153", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "NF-kappaB binding", "id": "GO:0051059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051059", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cellular response to tumor necrosis factor", "id": "GO:0071356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071356", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N7" } ], "pmid": "" }, { "name": "toll-like receptor 4 signaling pathway", "id": "GO:0034142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034142", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007643154", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643154" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tiam2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N8", "locus": {} } ], "crossref": [ { "id": "cd00136", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00136", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", 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"length": 1719, "header": "tr|A0A8C2N0N8-1|A0A8C2N0N8_CRIGR Isoform 1 of T-lymphoma invasion and metastasis-inducing protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tiam2 PE=3 SV=1 CANONICAL=A0A8C2N0N8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FGK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N8/entry#A0A9J7FGK5-1", "sequence": { "sequence": "MDAPMEREDPPSRPPARHLSDADRLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLEDGISASSDFNVLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDHESEEHYHLTEALKAMEKVASHINEMQKIYEDYGTVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGKARKDIELTVFVFKRAVILVYKENCKLKKKPPSNSRPAHNSADLDPFKFRWLIPISALQVRLGNTAGTENNSIWELIHTKSEIEGRPETIFQLCCSDSESKTSIVKVIRSILRENFRRHIKCELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKVLRTSSSSEWPGEPSKGNSLDSDECSLSSGTQSSGCPVAEHRQDSKGTVIEKDPHEGLAEFPDGLKESDILSDEDEDLHHPLKQGSPTKDIELQFQRLRISEEPDTHPAGQQPTTGPGEQPRLVRGHFCPIKRKANSTKRGRGTLLKAQTRHQSLDSHPETASIDLNLVLEREFSVQSLTSVVNEECFYEAQSHGKS", "length": 618, "header": "tr|A0A9J7FGK5-1|A0A8C2N0N8_CRIGR Computationally mapped isoform of T-lymphoma invasion and metastasis-inducing protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tiam2 PE=3 SV=1 CANONICAL=A0A8C2N0N8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 233, "start_aa": "Thr", "end_pos": 233, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr233", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FGK5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGK5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FGK5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGK5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771450", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771450", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9RSK9-1", "protein_name": "TIAM Rac1 associated GEF 2", "gene_name": "TIAM2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGNSESQYTLQGPKNHSNTITGAKQKPCSLKIRGLHAKDDKSLHGWGHGSSGAGYKSRSLARSCLSHFKSNQPYASRPGGPTCKASKGSAYAKHRTGAAGSDFQGTDAAFSPENGFHYVGRPPEENHSASRDCRNGHLLNCYGGNESIASTPPGEDRKSPRVLIKTLGKLDGCLRVEFHSGAAPPGASPSGGPVQLLRYSAGSAPSPSASPAAAARPRSSKGSSLSSESSWYDSPWGPAGEVSEAEGSFVAPDTPEPGLHTGFPTRDAPKPFSQSASLSSLRDPYPNASLGSLAPAALRLSDDYMGTRASLSARVSFASDMDVPARVERGEPGQFASFTLPCRKSRALGEESSKKDTLKARMRRISDWTGSLSRKKRRLQEPRSKEGSDYFDSRSDGLNVDTQGPSQGSVSLWSGGSAQILSHRSESAHAIGSDPLQQNIYENFMRELEMSRTNTENLETSTETAESSSESLSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQKERKLELVARRKWKQYWVTLKGCTLLFYETYGKNSMDQSSAPRCALFAEDSIVQSVPEHPKKENVFCLSNSFGDVYLFQATSQTDLENWVTAIHSACASLFAKKHGKEDTVRLLKNQTRNLLQKIDMDSKMKKMAELQLSVVSDPKNRKAIENQIQQWEQNLEKFHMDLFRMRCYLASLQGGELPNPKSLLAAASRPSKLALGRLGILSVSSFHALVCSRDDSALRKRTLSLTQRGRHKKGLFSSLKGLDTLARKGKEKRPSITQIFDSSGSHGFSGTQLPQSSNNSSEVDDLLHLYGSAVDGVPRDGTWESQVDVHFPDRQVVTVMVKPETRVEDVLTLACKMRQLEPSHYGLQLRKLVDENVEYCIPAPYEYMQDQVYDEIEVFPLSVYDVQLTKTGGVSDFGFAVTAQVDEHQHLSRIFISDVLPDGLAYGEGLRKGNEIMTLNGEAVSDLDLKQMEALFSEKSVGLTLIARPPDTKATLCSSWSDSDLFSRDQKGLLPPPNQSQLLEEFLDHFKKDTANDFSNVPDVTTGLKRSQTDGTLDQVSHREKKEQTFRSAEQITALCRNFNDTQANGMEGPREGQDPAPRPLARHLSDADRLRKVIQELMDTEKSYVKDLSCLFDLYLEPLQSETFLTQDEMESLFGSLPEMLEFQKVFLETLEDGISASSDFNILETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDHESEEHYHLTEALKAMEKVASHINEMQKIYEDYGTVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGKARKDLELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHSNADLDPFKFRWLIPISALQVRLGNTAGTENNSLWELIHTKSEIEGRPETIFQLCCSDNESKTNIVKVIRSILRENFRRHIKCELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKVLKNSSSSEWPGEPGKGSSLDSDEGSLSSSTQSSGCPPAGRGQDTQQHPHAGLADFSDSLIKESDILSDDEDDYPQARRQGSPTKDIEIQFQRLRISEDPDAHPAEEPPSKDGQPKLVRGHFCAIKRKANSTKRDRGTLLKAQTRHQSLDSHPGNANLDLSSVLEREFSVQSLTSVVNEECFYETESHGKS", "length": 1693 }, "evidence": [ { "id": "A0A8C2N0N8", "url": "https://omabrowser.org/oma/group/A0A8C2N0N8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZMS5-1", "protein_name": "TIAM Rac1 associated GEF 2", "gene_name": "Tiam2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNSESQYTFQGSKNQSNTVTGAKQKPCSLKIRSIHAKDEKSLHGWAHGSGGAGYKSRSLARSCLSHFKSHQPYATRLNGPTCKVSKGTAYSKHRANAPGNDFQGNNGAFLPENGFHYVGRESGESHITSRDCNGHLLTCYGRHDSIASTPPGEDRRSPRVLIKTLGKLDGCLRVEFHNGGNPHKGPSEDPSEPVQLLRYSPTLAAETCPVPESRRLSGAGSSASQRPSPTDSCLRSSKGSSLSSESSWYDSPWGNAGEASEVDGTFLAPSALDPSLPSSFPPSDTKKPFNQSSSLSSLRELYKDANLGCRSPSGTCLSSNEYISSQVGLNNRVSFASDMDVPSRVDHRDTMQYSSFTLPCRKSKALTEDAAKKDTLKARMRRFSDWTGSLSRKKRKLQEPRSTEGSEYFDSHSDGLNADVQGPTQTSALLWSGGSAQTLPHRSESTHAIGSDPLQQNIYENFMRELEMSRTNMENAETSTETVESSSESLSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQKERKLELVARRKWKQYWVTLKGCTLMFYETYGKNSTDQNSAPRCALFAEDSIVQSVPEHPKKEHVFCLSNSYGDVYLFQATSQTDLENWITAIHSACASLFAKKHGKEDTVRLLKSQTRGLLQKIDMDSKMKKMAELQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQGGELPNPKSLLAATSRPSKLALGRLGVLSVSSFHALVCSRDDSALRKRTLSFTQRAKSKKGLFSSLKGLDTLARKGREKRASITQMFDSSHSHGYLGTQLPQNSTNSSEVHDLHLYGSSADSTLRDSTWEVQTYVHFQDNEGVTVIIKPEHRVEDVLALACKMRHLEPTRYGLQLRKVVDESVEWCVPALYEYMQEQVYDEIEVFPLSVYDVQLTKTGDMTDFGFAVTAQVDEHQHLSRIFISDVLPDSLAYGGGLRKGNEIRSLNGEAVSDLDLKQMEALFSEKSVGLTLVARPADTRASLCTSCSDSDLFSRDQKSLLPSPNQCQLLEEFLDNFKKTSTNDFSNVPDVTTGLKRSHTEGTLDQVPHREKMEQTFRSAEQIVELCRGTTSMEAPTDSRDPPPRPLARHLSDADRLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLEDGISASSDFSVLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLERAKTDRAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDHESEEHYHLTEALKAMEKVASHINEMQKIYEDYGTVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGKARKDIELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSADLDPFKFRWLIPISALQVRLGNTAGTENNSTWELIHTKSEIEGRPETIFQLCCSDSESKTSIVKVIRSILRENFRRHIKCELPMEKTCKDRLVPLKNRVPVSAKLASSRSLKVLRTSSSSEWPSDPSKGNSLDSDECSLSSGTQSSGCPVAESRQDCKSTVLEKDAHEVLAEFPDGLIKESDILSDEEEDFHHPLKQGSPTKDIELQFQRLRISEEPDMHSTGQQPPLTGPGEQPKLVRGHFCPIKRKANSTKRGRGTLLKAQTRHQSLDSHPETASIDLNLVLEREFSVQSLTSVVNEECFYETQSHGKS", "length": 1714 }, "evidence": [ { "id": "A0A8C2N0N8", "url": "https://omabrowser.org/oma/group/A0A8C2N0N8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZPF3-1", "protein_name": "Rho guanine nucleotide exchange factor TIAM2", "gene_name": "Tiam2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNSESQYTFQGSKNHSNTVTGAKQKPCSLKIRSVHAKDEKSLHGWTHGSSGAGYKSRSLARSCLSHFKNHQPYATRLSGPTCKVSKGTTYSKHRANTPGNDFQGNSGAFLPENGFHYVDRESEESHITSNGHLLTCYGRKESLASTPPGEDHRSPRVLIKTLGKLDGCLRVEFHNGGNPHKGTSEDPSGPVRLLRYSPTLASETCPVRETRRHSAAGSPSSQRPSPTDSRLRSSKGSSLSSESSWYDSPWGNAGEVSEVEGSFLAPSTPDPSLPSSFPPSDTKKPFNQSSSLSSLRELYKDPNLGCRSPSGTCLSSNEYISSQVSLNNRVSFASDMDVPSRVDHRDPLHYSSFTLPCRKSKALTEDAAKKDTLKARMRRFSDWTGSLSRKKRKLQEPRSMEGSEYFDSHSDGLNAEGQVPAQTSSLLWSGGSAQTLPHRSESTHAISVDPLRQNIYENFMRELEMSRSNTEHVETSTETMESSSESVSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQKERKLELVARRKWKQYWVTLKGCTLLFYETYGKNSTEQNSAPRCALFAEDSIVQSVPEHPKKEHVFCLSNSCGDVYLFQATSQTDLENWVTAIHSACASLFAKKHGKEDTVRLLKSQTRSLLQKIDMDSKMKKMAELQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQGGELPNPKSLLAATSRPSKLALGRLGVLSVSSFHALVCSRDDSTLRKRTLSLTQRGKSKKGIFSSLKGLDTLARKGREKRASITQMFDSSHSHGFLGTQLPQKSTNSNKAHDLHLYGSAVDSALRDSMWEVQTYVHFQDNEGVTVTIKPEHRVEDVLALVCKMRQLEPTHYGLQLRKVVDKSVEWCVPALYEYMQEQVYDEIEVFPLSVYDVQLTKTGDMTDFGFAVTVQVDEHQHLNRIFISDVLPDSLAYGGGLRKGNEITSLNGEPVSDLDIQQMEALFSEKSVGLTLVARPVTTRRTLCASWSDSDLFSRDQKSLPPSPNQSQLLEEFLDNFRKTATSDFSNVPEITTGLKRSQTEGTLDQVPHREKMEQTFLSADQIAELCRDLNNTHTNSMEAPTESHDPPPRPLARHLSDADRLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLEDAISASSDFSVLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQRVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDHESEEHYHLTEALKAMEKVASHINEMQKIYEDYGMVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGKARKDIELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSADLDPFKFRWLIPISALQVRLGNTAGTENNSTWELIHTKSEIEGRPETIFQLCCSDSENKTSIVKVIRSILRENFRRHIKCELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKGLRTSSSSEWPSEPSKGNSLDSDECSLSSGTQSSGCPVAESRRDSKSTELEKDAQEGLAEFPDGLIKESDILSDEDEDFHHPLKQGSPTKDIEIQFQRLKISEESDVHPVGQQPLTESGEQPKLVRGHFCPIKRKANSTKRGRGTLLKAQTRHQSLDSHPETASIDLNLVLEREFSVQSLTSVVNEEGFYETQSHGKS", "length": 1715 }, "evidence": [ { "id": "A0A8C2N0N8", "url": "https://omabrowser.org/oma/group/A0A8C2N0N8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IVF5-1", "protein_name": "Rho guanine nucleotide exchange factor TIAM2", "gene_name": "TIAM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNSDSQYTLQGSKNHSNTITGAKQIPCSLKIRGIHAKEEKSLHGWGHGSNGAGYKSRSLARSCLSHFKSNQPYASRLGGPTCKVSRGVAYSTHRTNAPGKDFQGISAAFSTENGFHSVGHELADNHITSRDCNGHLLNCYGRNESIASTPPGEDRKSPRVLIKTLGKLDGCLRVEFHNGGNPSKVPAEDCSEPVQLLRYSPTLASETSPVPEARRGSSADSLPSHRPSPTDSRLRSSKGSSLSSESSWYDSPWGNAGELSEAEGSFLAPGMPDPSLHASFPPGDAKKPFNQSSSLSSLRELYKDANLGSLSPSGIRLSDEYMGTHASLSNRVSFASDIDVPSRVAHGDPIQYSSFTLPCRKPKAFVEDTAKKDSLKARMRRISDWTGSLSRKKRKLQEPRSKEGSDYFDSRSDGLNTDVQGSSQASAFLWSGGSTQILSQRSESTHAIGSDPLRQNIYENFMRELEMSRTNTENIETSTETAESSSESLSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTVQKERKLELVARRKWKQYWVTLKGCTLLFYETYGKNSMDQSSAPRCALFAEDSIVQSVPEHPKKENVFCLSNSFGDVYLFQATSQTDLENWVTAVHSACASLFAKKHGKEDTLRLLKNQTKNLLQKIDMDSKMKKMAELQLSVVSDPKNRKAIENQIQQWEQNLEKFHMDLFRMRCYLASLQGGELPNPKSLLAAASRPSKLALGRLGILSVSSFHALVCSRDDSALRKRTLSLTQRGRNKKGIFSSLKGLDTLARKGKEKRPSITQVDELLHIYGSTVDGVPRDNAWEIQTYVHFQDNHGVTVGIKPEHRVEDILTLACKMRQLEPSHYGLQLRKLVDDNVEYCIPAPYEYMQQQVYDEIEVFPLNVYDVQLTKTGSVCDFGFAVTAQVDERQHLSRIFISDVLPDGLAYGEGLRKGNEIMTLNGEAVSDLDLKQMEALFSEKSVGLTLIARPPDTKATLCTSWSDSDLFSRDQKSLLPPPNQSQLLEEFLDNFKKNTANDFSNVPDITTGLKRSQTDGTLDQVSHREKMEQTFRSAEQITALCRSFNDSQANGMEGPRENQDPPPRSLARHLSDADRLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDQESEEHYHLTEALKAMEKVASHINEMQKIYEDYGTVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGKARKDLELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSTDLDPFKFRWLIPISALQVRLGNPAGTENNSIWELIHTKSEIEGRPETIFQLCCSDSESKTNIVKVIRSILRENFRRHIKCELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKVLKNSSSNEWTGETGKGTLLDSDEGSLSSGTQSSGCPTAEGRQDSKSTSPGKYPHPGLADFADNLIKESDILSDEDDDHRQTVKQGSPTKDIEIQFQRLRISEDPDVHPEAEQQPGPESGEGQKGGEQPKLVRGHFCPIKRKANSTKRDRGTLLKAQIRHQSLDSQSENATIDLNSVLEREFSVQSLTSVVSEECFYETESHGKS", "length": 1701 }, "evidence": [ { "id": "A0A8C2N0N8", "url": "https://omabrowser.org/oma/group/A0A8C2N0N8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N8" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N8" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1029, "end_pos": 1031, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1095, "end_pos": 1097, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1157, "end_pos": 1159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1438, "end_pos": 1440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1658, "end_pos": 1660, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 808, "end_pos": 810, "annotation": "n_glycosylation_sequon" }, { "start_pos": 811, "end_pos": 813, "annotation": "n_glycosylation_sequon" }, { "start_pos": 924, "end_pos": 926, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N0N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N8" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 1125, "end_pos": 1319, "start_aa": "Arg", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N0N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N8" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 916, "end_pos": 1002, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N0N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N8" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 509, "end_pos": 623, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N0N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N8" }, { "id": "PS50898", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50898" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RBD", "eco_id": "ECO_0000259", "start_pos": 836, "end_pos": 907, "start_aa": "Ile", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 233 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1029, "end_pos": 1031 }, { "start_pos": 1095, "end_pos": 1097 }, { "start_pos": 1157, "end_pos": 1159 }, { "start_pos": 1438, "end_pos": 1440 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 15, "end_pos": 17 }, { "start_pos": 1658, "end_pos": 1660 }, { "start_pos": 293, "end_pos": 295 }, { "start_pos": 559, "end_pos": 561 }, { "start_pos": 808, "end_pos": 810 }, { "start_pos": 811, "end_pos": 813 }, { "start_pos": 924, "end_pos": 926 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N0N9-1", "uniprot_ac": "A0A8C2N0N9", "uniprot_id": "A0A8C2N0N9_CRIGR", "mass": { "chemical_mass": 207840.0, "monoisotopic_mass": 207840.0 }, "refseq": { "ac": "XP_027265875", "name": "myotubularin-related protein 13 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265875" }, "gene_names": [ { "name": "Sbf2", "type": "recommended", "evidence": [ { "id": "A0A8C2N0N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N9" } ] }, { "name": "Sbf2", "type": "synonym", "evidence": [ { "id": "XP_027265875", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265875" } ] } ], "protein_names": [ { "name": "Myotubularin-related protein 13 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A8C2N0N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N9/entry#names_and_taxonomy" } ] }, { "name": "myotubularin-related protein 13 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027265875", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265875" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265875", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265875" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sbf2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N9", "locus": {} } ], "crossref": [ { "id": "cd01235", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01235", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13339", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13339", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764737", "url": "https://www.ncbi.nlm.nih.gov/gene/100764737", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764737", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764737", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N0N9", "url": "https://www.orthodb.org/?gene=A0A8C2N0N9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265875", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265875", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N0N9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLT8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLADYFIVVGYDHEKPGPGEGLGKIIQRFPQQDWDDTPFPQGIELFCQPGGWHLSRERKQPTFFVVVLTDIDSDRHYCSCLTFYEAEINLQGTKKEEIEGEEVSGLIQPAEVFAPKSLVLVSRLDYPEIFRACLGLIYTVYVDSLSVSLESLIANLCACLVPAAGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLNLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSIFKTDVHELLDVIIADLDGGTIKIPECIHLSSLPEPLLHQTQAALSLILHPDLEVADHAFPPPRTALSHSKMLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKTAFLGQRGLVENDFLTKVLNGMAFAGFVSERGPPYRACDLFDELVAFEVERIKVEENNPLKMIKHIRELAEQLFKNENPNPHMAFQKVPRPTEGSHLRVHILPFPKINEARVQELMQENLAKNQNAPPATRIEKKCVVPAGPPVVSIMDKVITVFNSAQRLEVVRNCISFIFENKTLETEKTLPAALRALKGKAARQCLTDELGLHVQQNRAILDHQQFDYIIRMMNCTLQDCSSLEEYNIAAALLPLTSAFYRKLAPGVSQFAYTCVQDHPIWTNQQFWETTFYNAVQEQVRSLYLSAKEDNHAPHLKQKLPNGQYQEKTAMDLAAEQLRLWPTLSKSTQQELVQHEESTVFSQAIHFANLMVNLLVPLDTSKNKLLRASAPGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENNDVANSVVRFIARFIDKVCTESGVTQDHIRSLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPALLPGEEIVCEGLRVLLDPDGREEATGGLLGGPQLLPAEGALFLTTYRILFRGTPHDQLVGEQTVVRSFPIASITKEKKITMQNQLQQNMQEGLQITSASFQLIKVAFDEEVSPEVVDIFKKQLMKFRYPQSIFSTFAFAAGQTTPQIILPKQKEKNTSFRTFSKTIVKGAKRAGKMTIGRQYLLKKRTGTIVEERVNRPGWNEEDDISVSDDSELPTSTTLKASEKSTMEQLVEKACFRDYQRLGLGTISGTSSRSKPEYFRITASNRLYSLCRSYPGLLVIPQAVQDSSLLRVARCYRHNRLPVVCWKNSRSGTLLLRSGGFHGKGVVGLFKSQNSPQAVSTSSLESSSSIEQEKYLQALLTAVTVHQKLRGNNTLTVRPALALSPGVWASLRSSTRLISSPTSFIDVGARLAGKDHSTSFSNSTYLQNQLLKRQAALYIFGEKSQLRSFKVEFALNCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLKALGDSEWFPQLHRVLQLALVVSEVLENGSSVLVCLEEGWDVTTQVTSLVQLLSDPFYRTIEGFRMLVEKEWLSFGHKFSQRSSLALNSQGSGFAPIFLQFLDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYERLEHGTLFDDKGDKHAKKGVCIWECIDKMHKRSPIFFNYLYSPVEIEALKPNVNVSSLKKWDYYTEETLSAGPSYDWVMLTPKHIPSEESEIAGGAGPQSQRRTVWPCYDDISCSQPDALTRLFSEIEKLEHKLNQTPEKWHQLWEKVTMDLKDEPRTDHTQSHSSGSPGLVSTNVPSYQKRPVLHPLDRSTVEDQSATIAPSNGVEHRAATLYSQYTSKNDDNRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVEMVLPAGPSMGAPKYTSDKAFFDLKTSKRVYNFCAQDGQSAQQWMDRIQSCISDV", "length": 1846, "header": "tr|A0A8C2N0N9-1|A0A8C2N0N9_CRIGR Isoform 1 of Myotubularin-related protein 13 isoform X3 OS=Cricetulus griseus OX=10029 GN=Sbf2 PE=3 SV=1 CANONICAL=A0A8C2N0N9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N0N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N9/entry#A0A8C2N0N9-1", "sequence": { "sequence": "MARLADYFIVVGYDHEKPGPGEGLGKIIQRFPQQDWDDTPFPQGIELFCQPGGWHLSRERKQPTFFVVVLTDIDSDRHYCSCLTFYEAEINLQGTKKEEIEGEEVSGLIQPAEVFAPKSLVLVSRLDYPEIFRACLGLIYTVYVDSLSVSLESLIANLCACLVPAAGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLNLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSIFKTDVHELLDVIIADLDGGTIKIPECIHLSSLPEPLLHQTQAALSLILHPDLEVADHAFPPPRTALSHSKMLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKTAFLGQRGLVENDFLTKVLNGMAFAGFVSERGPPYRACDLFDELVAFEVERIKVEENNPLKMIKHIRELAEQLFKNENPNPHMAFQKVPRPTEGSHLRVHILPFPKINEARVQELMQENLAKNQNAPPATRIEKKCVVPAGPPVVSIMDKVITVFNSAQRLEVVRNCISFIFENKTLETEKTLPAALRALKGKAARQCLTDELGLHVQQNRAILDHQQFDYIIRMMNCTLQDCSSLEEYNIAAALLPLTSAFYRKLAPGVSQFAYTCVQDHPIWTNQQFWETTFYNAVQEQVRSLYLSAKEDNHAPHLKQKLPNGQYQEKTAMDLAAEQLRLWPTLSKSTQQELVQHEESTVFSQAIHFANLMVNLLVPLDTSKNKLLRASAPGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENNDVANSVVRFIARFIDKVCTESGVTQDHIRSLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPALLPGEEIVCEGLRVLLDPDGREEATGGLLGGPQLLPAEGALFLTTYRILFRGTPHDQLVGEQTVVRSFPIASITKEKKITMQNQLQQNMQEGLQITSASFQLIKVAFDEEVSPEVVDIFKKQLMKFRYPQSIFSTFAFAAGQTTPQIILPKQKEKNTSFRTFSKTIVKGAKRAGKMTIGRQYLLKKRTGTIVEERVNRPGWNEEDDISVSDDSELPTSTTLKASEKSTMEQLVEKACFRDYQRLGLGTISGTSSRSKPEYFRITASNRLYSLCRSYPGLLVIPQAVQDSSLLRVARCYRHNRLPVVCWKNSRSGTLLLRSGGFHGKGVVGLFKSQNSPQAVSTSSLESSSSIEQEKYLQALLTAVTVHQKLRGNNTLTVRPALALSPGVWASLRSSTRLISSPTSFIDVGARLAGKDHSTSFSNSTYLQNQLLKRQAALYIFGEKSQLRSFKVEFALNCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLKALGDSEWFPQLHRVLQLALVVSEVLENGSSVLVCLEEGWDVTTQVTSLVQLLSDPFYRTIEGFRMLVEKEWLSFGHKFSQRSSLALNSQGSGFAPIFLQFLDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYERLEHGTLFDDKGDKHAKKGVCIWECIDKMHKRSPIFFNYLYSPVEIEALKPNVNVSSLKKWDYYTEETLSAGPSYDWVMLTPKHIPSEESEIAGGAGPQSQRRTVWPCYDDISCSQPDALTRLFSEIEKLEHKLNQTPEKWHQLWEKVTMDLKDEPRTDHTQSHSSGSPGLVSTNVPSYQKRPVLHPLDRSTVEDQSATIAPSNGVEHRAATLYSQYTSKNDDNRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVEMVLPAGPSMGAPKYTSDKAFFDLKTSKRVYNFCAQDGQSAQQWMDRIQSCISDV", "length": 1846, "header": "tr|A0A8C2N0N9-1|A0A8C2N0N9_CRIGR Isoform 1 of Myotubularin-related protein 13 isoform X3 OS=Cricetulus griseus OX=10029 GN=Sbf2 PE=3 SV=1 CANONICAL=A0A8C2N0N9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JLT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N9/entry#A0A9J7JLT8-1", "sequence": { "sequence": "MARLADYFIVVGYDHEKPGPGEGLGKIIQRFPQQDWDDTPFPQGIELFCQPGGWHLSRERKQPTFFVVVLTDIDSDRHYCSCLTFYEAEINLQGTKKEEIEGEEVSGLIQPAEVFAPKSLVLVSRLDYPEIFRKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLNLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSIFKTDVHELLDVIIADLDGGTIKIPECIHLSSLPEPLLHQTQAALSLILHPDLEVADHAFPPPRTALSHSKMLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKTAFLGQRGLVENDFLTKVLNGMAFAGFVSERGPPYRACDLFDELVAFEVERIKVEENNPLKMIKHIRELAEQLFKNENPNPHMAFQKVPRPTEGSHLRVHILPFPKINEARVQELMQENLAKNQNAPPATRIEKKCVVPAGPPVVSIMDKVITVFNSAQRLEVVRNCISFIFENKTLETEKTLPAALRALKGKAARQCLTDELGLHVQQNRAILDHQQFDYIIRMMNCTLQDCSSLEEYNIAAALLPLTSAFYRKLAPGVSQFAYTCVQDHPIWTNQQFWETTFYNAVQEQVRSLYLSAKEDNHAPHLKQKLPNGQYQEKTAMDLAAEQLRLWPTLSKSTQQELVQHEESTVFSQAIHFANLMVNLLVPLDTSKNKLLRASAPGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENNDVANSVVRFIARFIDKVCTESGVTQDHIRSLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPALLPGEEIVCEGLRVLLDPDGREEATGGLLGGPQLLPAEGALFLTTYRILFRGTPHDQLVGEQTVVRSFPIASITKEKKITMQNQLQQNMQEGLQITSASFQLIKVAFDEEVSPEVVDIFKKQLMKFRYPQSIFSTFAFAAGQTTPQIILPKQKEKNTSFRTFSKTIVKGAKRAGKMTIGRQYLLKKRTGTIVEERVNRPGWNEEDDISVSDDSELPTSTTLKASEKSTMEQLVEKACFRDYQRLGLGTISGTSSRSKPEYFRITASNRLYSLCRSYPGLLVIPQAVQDSSLLRVARCYRHNRLPVVCWKNSRSGTLLLRSGGFHGKGVVGLFKSQNSPQAVSTSSLESSSSIEQEKYLQALLTAVTVHQKLRGNNTLTVRPALALSPGVWASLRSSTRLISSPTSFIDVGARLAGKDHSTSFSNSTYLQNQLLKRQAALYIFGEKSQLRSFKVEFALNCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLKALGDSEWFPQLHRVLQLALVVSEVLENGSSVLVCLEEGWDVTTQVTSLVQLLSDPFYRTIEGFRMLVEKEWLSFGHKFSQRSSLALNSQGSGFAPIFLQFLDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYERLEHGTLFDDKGDKHAKKGVCIWECIDKMHKRSPIFFNYLYSPVEIEALKPNVNVSSLKKWDYYTEETLSAGPSYDWVMLTPKHIPSEESEIAGGAGPQSQRRTVWPCYDDISCSQPDALTRLFSEIEKLEHKLNQTPEKWHQLWEKVTMDLKDEPRTDHTQSHSSGSPGLVSTNVPSYQKRPVLHPLDRSTVEDQSATIAPSNGVEHRAATLYSQYTSKNDDNRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVEMVLPAGPSMGAPKYTSDKAFFDLKTSKRVYNFCAQDGQSAQQWMDRIQSCISDV", "length": 1809, "header": "tr|A0A9J7JLT8-1|A0A8C2N0N9_CRIGR Computationally mapped isoform of Myotubularin-related protein 13 isoform X3 OS=Cricetulus griseus OX=10029 GN=Sbf2 PE=3 SV=1 CANONICAL=A0A8C2N0N9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 480, "start_aa": "Thr", "end_pos": 480, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr480", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JLT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLT8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JLT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLT8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764737", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764737", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N9" } ], "pmid": "" }, { "name": "phosphatase regulator activity", "id": "GO:0019208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019208", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0N9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1030, "end_pos": 1032, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1248, "end_pos": 1250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1298, "end_pos": 1300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1399, "end_pos": 1401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1570, "end_pos": 1572, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1651, "end_pos": 1653, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1740, "end_pos": 1742, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 615, "end_pos": 617, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N0N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N9" }, { "id": "PS51339", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51339" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myotubularin phosphatase", "eco_id": "ECO_0000259", "start_pos": 1105, "end_pos": 1581, "start_aa": "Gln", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N0N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N9" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 1740, "end_pos": 1844, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N0N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0N9" }, { "id": "PS50211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDENN", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 426, "start_aa": "Tyr", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 480 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1030, "end_pos": 1032 }, { "start_pos": 1248, "end_pos": 1250 }, { "start_pos": 1298, "end_pos": 1300 }, { "start_pos": 1399, "end_pos": 1401 }, { "start_pos": 1570, "end_pos": 1572 }, { "start_pos": 1651, "end_pos": 1653 }, { "start_pos": 1740, "end_pos": 1742 }, { "start_pos": 562, "end_pos": 564 }, { "start_pos": 615, "end_pos": 617 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N0V2-1", "uniprot_ac": "A0A8C2N0V2", "uniprot_id": "A0A8C2N0V2_CRIGR", "mass": { "chemical_mass": 52512.0, "monoisotopic_mass": 52512.0 }, "refseq": { "ac": "XP_035302214", "name": "ADP-ribose glycohydrolase MACROD2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302214" }, "gene_names": [ { "name": "Macrod2", "type": "recommended", "evidence": [ { "id": "A0A8C2N0V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0V2" } ] }, { "name": "Macrod2", "type": "synonym", "evidence": [ { "id": "XP_035302214", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302214" } ] } ], "protein_names": [ { "name": "ADP-ribose glycohydrolase MACROD2 isoform X3", "type": "synonym", "evidence": [ { 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035293913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293913", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N0X0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0X0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N249", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N249", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N249-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N249-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPAALVEAIVEEVNCPICMTFLREPVSISCGHTFCHSCLSGLWKLSGESQDWGYTCPLCRAPVQPRKLRPNWQLASVVDKVRLLGFCVEMGLKTDVCTLHKEPLTMFCKEDDVVTCKACNQSPAHEAHSVVPVKDVAWEYKWKLQEALGLLRKGQEEAWKLEVREKEQAARWKTQMEIRKQSILWEFEKYQQLLKEKELPCAQVEEEAAAAQASLEQEERETLNKLELRHEKIIQQSQVLWRMIVELEERSQRPVRWMVQGIQEALNRSKSWSFQQPEPISLELKTGCCVPGLREILKTYAVDVRLDPDTAYSRLVVSKDRKSVHYGDTQQNLPDNPERFYRYNIVLGSQCISSGRHYWEVEVGNRSEWGLGVCMENVDRKEVVYLSPHYGFWVIRLRKGTEYRAGTDEYPLLPLSVPPHRVGIFLDYEAHDISFYNVTDDGSHIFTFPHYPFPGRLLPYFSPCYSIATNNTTPLTICSLVGED", "length": 485, "header": "tr|A0A8C2N0X0-1|A0A8C2N0X0_CRIGR Isoform 1 of E3 ubiquitin-protein ligase TRIM68 isoform X1 OS=Cricetulus griseus OX=10029 GN=Trim68 PE=3 SV=1 CANONICAL=A0A8C2N0X0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N0X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0X0/entry#A0A8C2N0X0-1", "sequence": { "sequence": "MDPAALVEAIVEEVNCPICMTFLREPVSISCGHTFCHSCLSGLWKLSGESQDWGYTCPLCRAPVQPRKLRPNWQLASVVDKVRLLGFCVEMGLKTDVCTLHKEPLTMFCKEDDVVTCKACNQSPAHEAHSVVPVKDVAWEYKWKLQEALGLLRKGQEEAWKLEVREKEQAARWKTQMEIRKQSILWEFEKYQQLLKEKELPCAQVEEEAAAAQASLEQEERETLNKLELRHEKIIQQSQVLWRMIVELEERSQRPVRWMVQGIQEALNRSKSWSFQQPEPISLELKTGCCVPGLREILKTYAVDVRLDPDTAYSRLVVSKDRKSVHYGDTQQNLPDNPERFYRYNIVLGSQCISSGRHYWEVEVGNRSEWGLGVCMENVDRKEVVYLSPHYGFWVIRLRKGTEYRAGTDEYPLLPLSVPPHRVGIFLDYEAHDISFYNVTDDGSHIFTFPHYPFPGRLLPYFSPCYSIATNNTTPLTICSLVGED", "length": 485, "header": "tr|A0A8C2N0X0-1|A0A8C2N0X0_CRIGR Isoform 1 of E3 ubiquitin-protein ligase TRIM68 isoform X1 OS=Cricetulus griseus OX=10029 GN=Trim68 PE=3 SV=1 CANONICAL=A0A8C2N0X0-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N249-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0X0/entry#A0A8C2N249-1", "sequence": { "sequence": "MDPAALVEAIVEEVNCPICMTFLREPVSISCGHTFCHSCLSGLWKLSGESQDWGYTCPLCRAPVQPRKLRPNWQLASVVDKVRLLGFCVEMGLKTDVCTLHKEPLTMFCKEDDVVTCKACNQSPAHEAHSVVPVKDVAWEYKWKLQEALGLLRKGQEEAWKLEVREKEQAARWKTQMEIRKQSILWEFEKYQQLLKEKELPCAQVEEEAAAAQASLEQEERETLNKLELRHEKIIQQSQVLWRMIVELEERSQRPVRWMVQEQILELSAARANLLGAKDRLLCARTKRDPKDICSGCAPRSRHSLLPPCRVQGQKKCALWRHPTEPA", "length": 327, "header": "tr|A0A8C2N249-1|A0A8C2N0X0_CRIGR Computationally mapped isoform of E3 ubiquitin-protein ligase TRIM68 isoform X1 OS=Cricetulus griseus OX=10029 GN=Trim68 PE=3 SV=1 CANONICAL=A0A8C2N0X0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N249", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N249" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N249", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N249" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760957", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760957", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1B0GWT9-1", "protein_name": "Tripartite motif containing 68", "gene_name": "Trim68", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPAVLVDAIVEEVNCPICMTLLREPVSITCGHTFCHSCLSGLWRLPGDSQNLSYTCPLCRAPVQPRKLRPNWQLASVVDKVRLLGFCMEMGLKTDMCDLHKEQLTMFCKEDDVVTCKACNKSPEHGAHSVVPIKDVAWEYKWKLQQALEHLRKEQEKVWKLEVSEKEQAAIWKTQMETRKQSILWEFEKYQQLLKEKELPCQQAEEEAAAVQAGLEQEKGEMGNKLRLRHEKMIQQSQVLWQMIVELEERSQRPVRWMMQGIQEALNRSKSWSLQQLEPISLELKTDCRVLGLREILKTFAVDVRLDPDTAYSRLVISKDRKSVHYGVTQQNLPDNPERFYRYNIVLGSQCISSGRHYWEVEVGDRSEWGLGVCVESVDRKEVVYLSPRYGFWVIRLRKGTEYRAGTDEYPLLPLSVPPHRVGIFLDYEAHDISFYNVTDAGSHIFTFPRYPFPGRLLPYFSPCYSIGTNNTTPITICTLDGEG", "length": 485 }, "evidence": [ { "id": "A0A8C2N0X0", "url": "https://omabrowser.org/oma/group/A0A8C2N0X0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BQ22-1", "protein_name": "Tripartite motif containing 68", "gene_name": "TRIM68", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPATLMEAVVEEVACPICMTFLKEPVSIDCGHSFCHSCLLGLWEVPGESQNWAYSCPLCRAPIEPRNLRPNWQLANVVEKVRRLGLHPGMGLRADMCEPHREQLKMFCKEDGLIVCEACSRSPEHQAHSVVPMEDVAWDYKWKLHEALEHLKKEQEEAWKLEVGERKRTANWKIQVETRKQSIIWEFEKYRRLLKKKQPPGRLLEVEAAAALASLQQEERETMQKLELNHEALIQQSRVLWRMIAELEERSQRPVRWMLQGIQEVLNRSNSWSLQRPEPVSLELKTDCRVLGLREILKTYAADVRLDPDTAYSRLIVSEDRKCVRYGDTKQKLPDNPERFYRYNIVLGSQCISSGRHYWEVEVGDRSEWGLGVCKENVDRKEVVFLSPHYGFWVIRLRKGNEYRAGTDEYPLLSLPVPPRRVGVFLDYEAHDISFYNVTDNGSHIFTFPHYPFPGRLLPYFSPCYSIGANNTAPLAICSLDGED", "length": 485 }, "evidence": [ { "id": "A0A8C2N0X0", "url": "https://omabrowser.org/oma/group/A0A8C2N0X0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6AZZ1-1", "protein_name": "E3 ubiquitin-protein ligase TRIM68", "gene_name": "TRIM68", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPTALVEAIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPVQPRNLRPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEACSQSPEHEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLWRMIAELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRVLGLREILKTYAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLGSQCISSGRHYWEVEVGDRSEWGLGVCKQNVDRKEVVYLSPHYGFWVIRLRKGNEYRAGTDEYPILSLPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPYFSPCYSIGTNNTAPLAICSLDGED", "length": 485 }, "evidence": [ { "id": "A0A8C2N0X0", "url": "https://omabrowser.org/oma/group/A0A8C2N0X0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K243-1", "protein_name": "E3 ubiquitin-protein ligase TRIM68", "gene_name": "Trim68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPAVLMEAIVEEVNCPICMTFLREPVSISCGHTFCHSCLSGLWKLPGESQNLSYTCPLCRAPVKPRKLRPNWQLASVVDKVRLLGFCMEMGLKTDVCDLHKEQLTMFCKEDDMVTCEACKQSPEHEAHSVVPIKDVAWEYKWKLQQALEHLRKEQEEAWKLEVSEKEQAAIWKTQMERRKQSIRWEFEKYRQLLKEKELPCQQAEEEAAAAQASLEQEKGETASKLELRREAIIRQSQVLWSMIVELEERSQRPVRWMLQGIQEALNRSESWTLQQLEPISLELKTDCRVLGLRETLKTFAVDVRLDPDTAYSRLVVSKDRKSVHYGVTQQNLPDNPERFYRYNIVLGSQCISSGRHYWEVEVGDRSEWGLGVCVENVDRKEVVYLSPRYGFWVIRLRKGTEYRAGTDEYPLLPLTVPPHRVGIFLDYEAHDISFYNVTDGASHIFTFPCYPFPGRLLPYFSPCYSIDTNNTTPLTICTLGGEG", "length": 485 }, "evidence": [ { "id": "A0A8C2N0X0", "url": "https://omabrowser.org/oma/group/A0A8C2N0X0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0X0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0X0" } ], "pmid": "" }, 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"database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HMACNIG", "url": "https://omabrowser.org/oma/group/HMACNIG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N131", "url": "https://www.orthodb.org/?gene=A0A8C2N131", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46078", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46078", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46078:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46078:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027254919", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254919", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N131", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N131", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N131-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N131-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N1L6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N1L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1L6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FCE2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FCE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JDX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JDX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K4H0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K4H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4H0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTAISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDTLPTRSKKRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVSQSLTPQQQPQYNLPERDKQLLFTEYNFEDLSASFRSLYKSVFEQSLSQQGLMSIPSESSQQSHTSCSYQHSPSSTVSSHPHSNQSSLPNSHSGLNATGSNSVAQVSLSHPQMHTQPSPHTPHRPHGLPQHPQRPQHPASHPQQHSQLQPPHTQHPSPHQHIQHHPNHQHQTLAHQPPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPAKPSQHIGAGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTMAGHHGAMNQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "length": 621, "header": "tr|A0A8C2N131-1|A0A8C2N131_CRIGR Isoform 1 of Forkhead box protein J3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Foxj3 PE=4 SV=1 CANONICAL=A0A8C2N131-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N131-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N131/entry#A0A8C2N131-1", "sequence": { "sequence": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTAISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDTLPTRSKKRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVSQSLTPQQQPQYNLPERDKQLLFTEYNFEDLSASFRSLYKSVFEQSLSQQGLMSIPSESSQQSHTSCSYQHSPSSTVSSHPHSNQSSLPNSHSGLNATGSNSVAQVSLSHPQMHTQPSPHTPHRPHGLPQHPQRPQHPASHPQQHSQLQPPHTQHPSPHQHIQHHPNHQHQTLAHQPPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPAKPSQHIGAGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTMAGHHGAMNQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "length": 621, "header": "tr|A0A8C2N131-1|A0A8C2N131_CRIGR Isoform 1 of Forkhead box protein J3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Foxj3 PE=4 SV=1 CANONICAL=A0A8C2N131-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N1L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N131/entry#A0A8C2N1L6-1", "sequence": { "sequence": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTAISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDTLPTRSKKRARSVERVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVSQSLTPQQQPQYNLPERDKQLLFTEYNFEDLSASFRSLYKSVFEQSLSQQGLMSIPSESSQQSHTSCSYQHSPSSTVSSHPHSNQSSLPNSHSGLNATGSNSVAQVSLSHPQMHTQPSPHTPHRPHGLPQHPQRPQHPASHPQQHSQLQPPHTQHPSPHQHIQHHPNHQHQTLAHQPPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPAKPSQHIGAGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTMAGHHGAMNQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "length": 587, "header": "tr|A0A8C2N1L6-1|A0A8C2N1L6_CRIGR Computationally mapped isoform of Forkhead box protein J3 isoform X3 OS=Cricetulus griseus OX=10029 GN=Foxj3 PE=4 SV=1 CANONICAL=A0A8C2N131-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FCE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N131/entry#A0A9J7FCE2-1", "sequence": { "sequence": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTAISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKGSYWAIDTNPKEDTLPTRSKKRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVSQSLTPQQQPQYNLPERDKQLLFTEYNFEDLSASFRSLYKSVFEQSLSQQGLMSIPSESSQQSHTSCSYQHSPSSTVSSHPHSNQSSLPNSHSGLNATGSNSVAQVSLSHPQMHTQPSPHTPHRPHGLPQHPQRPQHPASHPQQHSQLQPPHTQHPSPHQHIQHHPNHQHQTLAHQPPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPAKPSQHIGAGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTMAGHHGAMNQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "length": 596, "header": "tr|A0A9J7FCE2-1|A0A8C2N131_CRIGR Computationally mapped isoform of Forkhead box protein J3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Foxj3 PE=4 SV=1 CANONICAL=A0A8C2N131-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JDX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N131/entry#A0A9J7JDX4-1", "sequence": { "sequence": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTAISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDTLPTRSKKRARSVERVTNHPEPVSQSLTPQQQPQYNLPERDKQLLFTEYNFEDLSASFRSLYKSVFEQSLSQQGLMSIPSESSQQSHTSCSYQHSPSSTVSSHPHSNQSSLPNSHSGLNATGSNSVAQVSLSHPQMHTQPSPHTPHRPHGLPQHPQRPQHPASHPQQHSQLQPPHTQHPSPHQHIQHHPNHQHQTLAHQPPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPAKPSQHIGAGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTMAGHHGAMNQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "length": 544, "header": "tr|A0A9J7JDX4-1|A0A9J7JDX4_CRIGR Computationally mapped isoform of Forkhead box protein J3 isoform X5 OS=Cricetulus griseus OX=10029 GN=Foxj3 PE=4 SV=1 CANONICAL=A0A8C2N131-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K4H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N131/entry#A0A9J7K4H0-1", "sequence": { "sequence": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTAISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKGSYWAIDTNPKEDTLPTRSKKRARSVERVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVSQSLTPQQQPQYNLPERDKQLLFTEYNFEDLSASFRSLYKSVFEQSLSQQGLMSIPSESSQQSHTSCSYQHSPSSTVSSHPHSNQSSLPNSHSGLNATGSNSVAQVSLSHPQMHTQPSPHTPHRPHGLPQHPQRPQHPASHPQQHSQLQPPHTQHPSPHQHIQHHPNHQHQTLAHQPPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPAKPSQHIGAGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTMAGHHGAMNQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "length": 562, "header": "tr|A0A9J7K4H0-1|A0A8C2N131_CRIGR Computationally mapped isoform of Forkhead box protein J3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Foxj3 PE=4 SV=1 CANONICAL=A0A8C2N131-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FCE2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCE2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FCE2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCE2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759136", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759136", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A806-1", "protein_name": "Forkhead box J3", "gene_name": "FOXJ3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKKSALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDALPTRPKKRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVSQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRSLYKSVFEQSLSQQGLMNIPSESSQQSHTSCSYQHSPSSTVSSHPHGNQSSLSNSHGSGLNATGSNSVAQVSLSHPQMHTQPSPHPPHRPHGLPQHPQRPQHPAAHPQQHGQLQSPHPQHPSPHQHMQHHPNHQHQTLAHQAPPPPQQVSCNSGVSNDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIGTGNLYMDSRQNLPPSVMPTPGYPHIPQALSTPGTTMAGHHGALNQQHVMPSQAFQMRRALPPDDIQDDFDWDSIV", "length": 622 }, "evidence": [ { "id": "A0A8C2N131", "url": "https://omabrowser.org/oma/group/A0A8C2N131/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8Q307-1", "protein_name": "Forkhead box protein J3", "gene_name": "foxj3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSELESSLTSMDWLPQLTMRAAIQKADAQNAHGPGMPKKSALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDTLPTRPKKRPRSGERASTPYSLESDNLGMDCIISGSASPTLAINTVTNKVALYNPDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTSHPESVSQSMSLQQAPQAQYSIPDRDKQLLFSEFEDLSASFRSLYKTVFEQSYNQQSLMGLPSESSQQTHTSCSYQHSPSSHPHNNQNSITNSHPNNIPNNGSQVPLSHPPHSAHNSPHGQHLSQHGPHSQHPHTAHSQHPQHSQHPQHSQHSQHGHQAHGQHTAQQQQQQHQNLSHQQQMQCNTGLLSDWYPNLDALKESCRIASNCNWSDVDLSPFQGLKESMRQAEMNNWSLEPTQMADLCSSINQFFAQTGIQPQGAVQASVCHGSMHPNKASPHINRVCFSGNVYMDSRPSLSSLMGPPGYTHMPPMSSAGPTMTGHHPQMSQQHMMTGGNFQMRRMPADDIQDDFDWDSIV", "length": 596 }, "evidence": [ { "id": "A0A8C2N131", "url": "https://omabrowser.org/oma/group/A0A8C2N131/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8I6AQ64-1", "protein_name": "Forkhead box J3", "gene_name": "Foxj3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDTLPTRPKKRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVSQSLTPQQQPQYNLPERDKQLLFTEYNFEDLSASFRSLYKSVFEQSLSQQGLMSIPSESSQQSHTSCSYQHSPSSTVTSHPHSNQSSLPNNHSGLSATGSNSVAQVSLSHPQMHTQPSPHTPHRPHGLPQHPQRPQHPASHPQQHSQLQPPHSQHPPPHQHIQHHPNHQHQTLAHQPPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNAQQNVCHGAMHPAKPSQHIGAGNLYIDSRQSGIPPSVMPPPGYPHIPQALNTPGTTMAGHHGAMNQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "length": 622 }, "evidence": [ { "id": "A0A8C2N131", "url": "https://omabrowser.org/oma/group/A0A8C2N131/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BUR3-1", "protein_name": "Forkhead box protein J3", "gene_name": "Foxj3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDTLPTRPKKRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNADQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVSQPLTPQQQQQPQYNLPEREKQLLFTEYNFEDLSASFRSLYKSVFEQSLSQQGLMSIPSESSQQSHTSCSYQHSPSSTVTSHPHSNQSSLPNNHSGLSATGSNSVAQVSLSHPQMHPQPSPHTPHRPHGLPQHPQRPQHPAPHPQQHSQLQPPHSQHPPPHQHIQHHPNHQHQTLAHQPPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVPQNVCHGAMHPAKPSQHIGAGNLYIDSRQSLPPSVMPPPGYPHIPQALNTPGTTMAGHHGAMNQQHMMPSQAFPMRRPLPPDDIQDDFDWDSIV", "length": 623 }, "evidence": [ { "id": "A0A8C2N131", "url": "https://omabrowser.org/oma/group/A0A8C2N131/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UPW0-1", "protein_name": "Forkhead box protein J3", "gene_name": "FOXJ3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDVLPTRPKKRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTSHPESVSQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRSLYKSVFEQSLSQQGLMNIPSESSQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGLNTTGSNSVAQVSLSHPQMHTQPSPHPPHRPHGLPQHPQRSPHPAPHPQQHSQLQSPHPQHPSPHQHIQHHPNHQHQTLTHQAPPPPQQVSCNSGVSNDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTMAGHHRAMNQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "length": 622 }, "evidence": [ { "id": "A0A8C2N131", "url": "https://omabrowser.org/oma/group/A0A8C2N131/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N131", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N131" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N131", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N131" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N131", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N131" } ], "pmid": "" }, { "name": "male meiosis I", "id": "GO:0007141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007141", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N131", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N131" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N131", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N131" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N131", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N131" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N131", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N131" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { 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] }, { "id": "PF00105", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00105", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027249620", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249620", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N135", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N135", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N135-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N135-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"MANTYVTASDGYCLAEPTQYYDILPEQIHYQLCDTDFQEASYCQYSTAQFPPALQSPSFQSHFNTYGLDPQYGSGGWCGLDACEASQSTYMFVHDDEDGFPGIQRSRPTCSLRWKGQDELCVVCGDKASGYHYNALTCEGCKGFFRRSITKNAVYSCKNGGHCEMDMYMRRKCQECRLKKCKAVGMLAECLLTEIQCKSKRLRKNSKQKIALYSDLQVEDEGTDSKLVSSTTRYGKGVQESLALTQEEHHLMNTIVTAHQKFMTPLGAASLLLQEYSNPEVSFLRLSEAAVLNIQGLMNFTKGLPGFENLTNEDQTALQKESKTEVMFLHVAHLYSGKESTSGSIMRPSKPSARTREVHNQSSEENVYSLENFFKQGSSSATLTGITEEFVTSLTYFYRRMSELNITDTEYALLTATTVLFSDRPSLKNKQQVENLQEPVLQLLFKYSKLYHPEEPQHFAHLIGRLTELRTLSHRHSEILSTWKTKDPRLVTILSEKWNLHSFN", "length": 504, "header": "tr|A0A8C2N135-1|A0A8C2N135_CRIGR Isoform 1 of Bile acid receptor isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100751364 PE=3 SV=1 CANONICAL=A0A8C2N135-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"MANTYVTTSDGYYLAEPTQYYDILPEQLHYQLCDTDFQEPPYSQYSTAQFPPALQSPSLQSHFSTYGLEPQYSGGSWCGLDTRESSQSTYVVVHDDEDEFPGTQRCRPTCSLRWKGQDELCMVCGDKASGYHYNALTCEGCKGFFRRSITKNAVYSCKNGGHCEMDMYMRRKCPECRLKKCKAVGMLAECLLTEIQCKSKRLRKSFKHRPTLSSAIQVEDEGTDTKHVSSTSRSGKGAQDDMTLTAEERRLLNTIVTAHRKSMVPVGEISALLQEYSNPELSFLRLSEASILHANWLMKFTKGLPGFENLTAEDQTALQKESKTEVMFLHVAQLYGGRDSTSGSTVRPAKPSAGTLEVHNHRGDECVYSSENFFKEGYPSATLTGITREFIASLSYFYRRMRELNITDTEYALLTATTVLFSDRPYLKNKQHVENLQEPVLQLLFKYSKMYHPEDPQHFAHLIGRLTELRTLSHSHSEILSTWKTKDPRLVMLFSEKWDLHSLY", "length": 504 }, "evidence": [ { "id": "A0A8C2N135", "url": "https://omabrowser.org/oma/group/A0A8C2N135/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q5A6-1", "protein_name": "Nuclear receptor subfamily 1, group H, member 5", "gene_name": "Nr1h5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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:: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613628.1) annotated using gene prediction method: Gnomon. 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:: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"MGANASNYPHSCSPRVGGNSQAQQTFIGTSSYSQQGYGCESKLYSLDHGHEKPQDKKKRTSGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASLARPEARTLQKDMADLYEYKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAEIIMDISTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLSEEFGTPNSLDVDMRGLFDYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAIISARSPFFRNLLQRRIRTGEEITDRTLRTPTRIILDESIIPKKYAKVILHCMYTDVVDLSVLHCSPSVGSLSEVQALVAGKPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLDTLIAILKWSSHPYGSKWVHRQALHFLCEELSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIADREPNLLSGTAHSVNKRGVKRRDLDIEELREILSSLLPFVRIEHILPINSEVLSDAMKRGLISTPPSDMLPTTEGGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRLRMVRMSNVPDTLYMVSSAMPQCCHMVSHQQVSSNQSSPPSVVANEIPVPRLLMMKDMVRRLQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDERFGDESPLLTMRQPGRCRVNSTPTAEPMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGWKQRPPSHHPSRSFSYPCNHSLFHSRTAPKPGPPPVYLPGVKVAPPDCTNTTGLGRQTVAAAAAAAASAAIISEKQVCTQPMLNDLMPDIAMGVSTLSLKDRRLPELAADTELCQPVSEAGPGPPQHLSCIPQRHTHTSRKKHALEQKADGRENQQEYPDLYDFSNAACRPSTPAPGRRTPSPPHGRYFGPDLYSHNKASPNGLKSAYLPGQTSPKKQEDARREYPLSPDGHLHKQKSEPIRLDVVEQPPQRSDFPSAASENAGNGPAHVRARTAVETDLTFGLTPNRPPSHSACSSEALEERSSRRLTDSESLSHGAQRNTDLERDDSISRGRRSPSKPDFLYKKSAL", "length": 1128, "header": "tr|A0A8C2N180-1|A0A8C2N180_CRIGR Isoform 1 of BTB/POZ domain-containing protein 7 OS=Cricetulus griseus OX=10029 GN=Btbd7 PE=4 SV=1 CANONICAL=A0A8C2N180-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N180-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N180/entry#A0A8C2N180-1", "sequence": { "sequence": "MGANASNYPHSCSPRVGGNSQAQQTFIGTSSYSQQGYGCESKLYSLDHGHEKPQDKKKRTSGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASLARPEARTLQKDMADLYEYKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAEIIMDISTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLSEEFGTPNSLDVDMRGLFDYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAIISARSPFFRNLLQRRIRTGEEITDRTLRTPTRIILDESIIPKKYAKVILHCMYTDVVDLSVLHCSPSVGSLSEVQALVAGKPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLDTLIAILKWSSHPYGSKWVHRQALHFLCEELSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIADREPNLLSGTAHSVNKRGVKRRDLDIEELREILSSLLPFVRIEHILPINSEVLSDAMKRGLISTPPSDMLPTTEGGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRLRMVRMSNVPDTLYMVSSAMPQCCHMVSHQQVSSNQSSPPSVVANEIPVPRLLMMKDMVRRLQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDERFGDESPLLTMRQPGRCRVNSTPTAEPMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGWKQRPPSHHPSRSFSYPCNHSLFHSRTAPKPGPPPVYLPGVKVAPPDCTNTTGLGRQTVAAAAAAAASAAIISEKQVCTQPMLNDLMPDIAMGVSTLSLKDRRLPELAADTELCQPVSEAGPGPPQHLSCIPQRHTHTSRKKHALEQKADGRENQQEYPDLYDFSNAACRPSTPAPGRRTPSPPHGRYFGPDLYSHNKASPNGLKSAYLPGQTSPKKQEDARREYPLSPDGHLHKQKSEPIRLDVVEQPPQRSDFPSAASENAGNGPAHVRARTAVETDLTFGLTPNRPPSHSACSSEALEERSSRRLTDSESLSHGAQRNTDLERDDSISRGRRSPSKPDFLYKKSAL", "length": 1128, "header": "tr|A0A8C2N180-1|A0A8C2N180_CRIGR Isoform 1 of BTB/POZ domain-containing protein 7 OS=Cricetulus griseus OX=10029 GN=Btbd7 PE=4 SV=1 CANONICAL=A0A8C2N180-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G6E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N180/entry#A0A9J7G6E0-1", "sequence": { "sequence": "MGANASNYPHSCSPRVGGNSQAQQTFIGTSSYSQQGYGCESKLYSLDHGHEKPQDKKKRTSGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASLARPEARTLQKDMADLYEYKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAEIIMDISTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLSEEFGTPNSLDVDMRGLFDYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAIISARSPFFRNLLQRRIRTGEEITDRTLRTPTRIILDESIIPKKYAKVILHCMYTDVVDLSVLHCSPSVGSLSEVQALVAGKPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLDTLIAILKWSSHPYGSKWVHRQALHFLCEELSQVMTSDVFYELSKDHLLTAIQSDYLQSQTY", "length": 461, "header": "tr|A0A9J7G6E0-1|A0A8C2N180_CRIGR Computationally mapped isoform of BTB/POZ domain-containing protein 7 OS=Cricetulus griseus OX=10029 GN=Btbd7 PE=4 SV=1 CANONICAL=A0A8C2N180-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765835", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765835", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N180", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N180" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "morphogenesis of a branching epithelium", "id": "GO:0061138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061138", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N180", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N180" } ], "pmid": "" }, { "name": "regulation of branching involved in salivary gland morphogenesis", "id": "GO:0060693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060693", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N180", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N180" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 634, "end_pos": 636, "annotation": "n_glycosylation_sequon" }, { "start_pos": 736, "end_pos": 738, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" }, { "start_pos": 798, "end_pos": 800, "annotation": "n_glycosylation_sequon" }, { "start_pos": 829, "end_pos": 831, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N180" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 142, "end_pos": 211, "start_aa": "Thr", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 363, "end_pos": 365 }, { "start_pos": 4, "end_pos": 6 }, { "start_pos": 634, "end_pos": 636 }, { "start_pos": 736, "end_pos": 738 }, { "start_pos": 77, "end_pos": 79 }, { "start_pos": 798, "end_pos": 800 }, { "start_pos": 829, "end_pos": 831 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N198-1", "uniprot_ac": "A0A8C2N198", "uniprot_id": "A0A8C2N198_CRIGR", "mass": { "chemical_mass": 47891.0, "monoisotopic_mass": 47891.0 }, "refseq": { "ac": "XP_027255529", "name": "transcription factor E2F2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255529" }, "gene_names": [ { "name": "E2f2", "type": "recommended", "evidence": [ { "id": "A0A8C2N198", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N198" } ] }, { "name": "E2f2", "type": "synonym", "evidence": [ { "id": "XP_027255529", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255529" } ] } ], "protein_names": [ { "name": "Transcription factor E2F2 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2N198", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N198/entry#names_and_taxonomy" } ] }, { "name": "transcription factor E2F2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027255529", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255529" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027259014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259014" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N1H7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1H7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Glipr2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1H7", "locus": {} } ], "crossref": [ { "id": "cd05382", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05382", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758797", "url": "https://www.ncbi.nlm.nih.gov/gene/100758797", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758797", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758797", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N1H7", "url": "https://www.orthodb.org/?gene=A0A8C2N1H7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00188", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00188", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027259014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259014", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N1H7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1H7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N1H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1H7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKSASKQFNNEVLKAHNEYRAQHGVPPLKLCKKLNQEAQQYSEALASTRILKHSPESSRGQCGENLAWASYDQTGKEVADRWYSEIKNYNFQQPGFTSGTGHFTAMVWKNTKKMGVGKASASDGSSFVVARYFPAGNVVNQGFFEENVLPPKK", "length": 154, "header": "tr|A0A8C2N1H7-1|A0A8C2N1H7_CRIGR Isoform 1 of Golgi-associated plant pathogenesis-related protein 1 OS=Cricetulus griseus OX=10029 GN=Glipr2 PE=3 SV=1 CANONICAL=A0A8C2N1H7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N1H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1H7/entry#A0A8C2N1H7-1", "sequence": { "sequence": "MGKSASKQFNNEVLKAHNEYRAQHGVPPLKLCKKLNQEAQQYSEALASTRILKHSPESSRGQCGENLAWASYDQTGKEVADRWYSEIKNYNFQQPGFTSGTGHFTAMVWKNTKKMGVGKASASDGSSFVVARYFPAGNVVNQGFFEENVLPPKK", "length": 154, "header": "tr|A0A8C2N1H7-1|A0A8C2N1H7_CRIGR Isoform 1 of Golgi-associated plant pathogenesis-related protein 1 OS=Cricetulus griseus OX=10029 GN=Glipr2 PE=3 SV=1 CANONICAL=A0A8C2N1H7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027247815", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247815" } ] }, { "annotation": "Binds DNA and may function as a transcriptional repressor.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N1H9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1H9#function" }, { "database": "UniProtKB", "id": "ARBA00059986", "url": "https://www.uniprot.org/uniprotkb/ARBA00059986#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N1H9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1H9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf639", "url": 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. 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:: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613699.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007628828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007628828" } ] }, { "annotation": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N1N3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1N3#function" }, { "database": "UniProtKB", "id": "PIRNR000777", "url": "https://www.uniprot.org/uniprotkb/PIRNR000777#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N1N3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1N3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Polr3gl", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1N3", "locus": {} } ], "crossref": [ { "id": "100755742", "url": "https://www.ncbi.nlm.nih.gov/gene/100755742", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KDLHAPF", "url": "https://omabrowser.org/oma/group/KDLHAPF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N1N3", "url": "https://www.orthodb.org/?gene=A0A8C2N1N3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J5C2", "url": "https://www.orthodb.org/?gene=A0A9J7J5C2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15367", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15367", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15367:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15367:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11705", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11705", 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SV=1 CANONICAL=A0A8C2N1N3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J5C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1N3/entry#A0A9J7J5C2-1", "sequence": { "sequence": "MGSSGRRAQSAGWRKKSEFQVGRCVGPGVGEGRQPLEFHPVPLPAGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERYSDKYQMSGPMDNAIDWNPDWRRLPRELKIRVRKLQKERATILLPKRPPKAMEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEDKEEGEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY", "length": 210, "header": "tr|A0A9J7J5C2-1|A0A9J7J5C2_CRIGR Computationally mapped isoform of DNA-directed RNA polymerase III subunit RPC7-like isoform X3 OS=Cricetulus griseus OX=10029 GN=Polr3gl PE=3 SV=1 CANONICAL=A0A8C2N1N3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KDP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1N3/entry#A0A9J7KDP2-1", "sequence": { "sequence": "MRQLPYFIRPAVPKRDVERYSDKYQMSGPMDNAIDWNPDWRRLPRELKIRVRKLQKERATILLPKRPPKAMEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEDKEEGEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY", "length": 148, "header": "tr|A0A9J7KDP2-1|A0A8C2N1N3_CRIGR Computationally 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N1V9-1", "uniprot_ac": "A0A8C2N1V9", "uniprot_id": "A0A8C2N1V9_CRIGR", "mass": { "chemical_mass": 245423.0, "monoisotopic_mass": 245423.0 }, "refseq": { "ac": "XP_027259516", "name": "zinc finger protein 407 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259516" }, "gene_names": [ { "name": "Znf407", "type": "recommended", "evidence": [ { "id": "A0A8C2N1V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1V9" } ] }, { "name": "Znf407", "type": "synonym", "evidence": [ { "id": "XP_027259516", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259516" } ] } ], "protein_names": [ { "name": "Zinc finger protein 407 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2N1V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1V9/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 407 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027259516", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259516" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027259516", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259516" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N1V9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1V9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf407", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1V9", "locus": {} } ], "crossref": [ { "id": "100760917", "url": "https://www.ncbi.nlm.nih.gov/gene/100760917", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050688", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050688", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760917", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760917", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N1V9", "url": "https://www.orthodb.org/?gene=A0A8C2N1V9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403:SF60", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403:SF60", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027259516", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259516", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N1V9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N1V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1V9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GR62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GR62-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSDNKHENDEDEEARDMKSISSHDAICGPVSDGIANASENFTNKRGLSESSSLDSVAVEEDRSELASKRMRIEVVEPLEMGEQGTCGLDTVEASVHSAEARKEAFPTISSDGGRALPSDFSPSCDFSMFDTLPLKADAVRKPAQEMSSLVPERHTPFPPEEMSIGCSFGNAESVLKCSMCGHSFSSCSALEKHVECHVEQDKECACCHCSHRAESSSSPPHMHVKHTHGPQKTFSCDLCGFQCAEENLLNAHYLGKTHLRRQNLAARGGFVQILTKQPFPKKACVMGTKNVRTKPRASKPIARNGDSKGVQNTGNKFKDCRGAPSERNGGRSELLVQMVPSRNTSSGKGEIVEENATLGVVQNPENQNKQLGGLVSSEGLLGKSEPIRNTLQIAHISISATSRPRSERNILMLGNSFRRRSGTFTLKGQAKKRYNLLGINKRSASETQRVYMKHFRTQMKTNDTQPVTEQLQRSKDVQSLCVTTSDDPKVMQNKTASCFSDSTQLGSLPVKPASDLQVLCTSPECGHIAADKTDLEIHVKGCHAREMQFHCQTCNYSSPSRKDLEKHLHSNQHQDMTPVLSCQCCSFISLNEMSLRDHMKEKHSMGFFCTSCNLFLSEKDVEEHRATEMHNSLVVQPKMASVSPLSTLESENMDDSREESGKAAKADPTELRVSHGTEARHSSKPQFQCKKCFYKTRSSTVLTRHIKLRHGQDYHFLCKACNLYSLSKEGMEKHIKRSKHLENAKKNNIGLSFEECIERVCIGANDKKEESNSSGSGRPEGHVGVRLQEPFHREQSLLTPKELPQSDVITKDEELALATTPKRGRPKGSISRTCSHCGLLASSITNLTVHIRRKHSHQYSYLCKVCKYYTVTKGDMERHCATKKHKGRVEIEANGKQSSDIIVGPEGGNLEACKKNAPPAVTVSDEQANKSTESDTSTLDKPVVDCASAVEVEAASAFHSVEGEVSSQLSDKRGQMSLETEDLLQQSDACSQRDVAGSGDNKCVHCEFSAHSAASLELHVKRKHTKEFEFYCMACDYYAVTRREMTRHAATEKHKMKRQSYLNSSSADAGSSEMSKSILLSQEEHSQNPEELKITPDQSCGTLKSGNAAGCSVLDENTNLDMSKVLCATDSVEIVPEEDHSFCETLQQPLVKDKSIKPREIVSLSTPSNHGFPDCLQNENPGSSAVDCETAKRKHGMLNDAGDLSTHCEDEGGSADDSARKVPDKTLCSGDLDGGHSAAATSPVVLKIPRDHLHLDGGDQNKVGCEQSSEDFKHVHASVVEKKEVLMNSKHRTESVLEEDGPASDDTVDSNDVYETIISIDDKGQTMYSFGRFDSSIIRIKTCEDGELVDQSEEGLMATGARVSELPLKESAQGLKRRKVEGNSFGESTRIRCDDCGFLADGLSGLNVHIAMKHPTKEKHFHCLLCGKSFYTESNLHQHLASAGHMRNEQASVEELPEGGATFKCVKCTEPFDSEQNLFLHIKGQHEELLREVNKYIVEDTEQINREREENQGNICKYCGKMCRSSNSMAFLAHIRTHTGSKPFKCKICHFATAQLGDARNHVKRHLGMREYKCHVCGVAFVMKKHLNTHLLGKHGVGTPKERKFTCHLCDRSFTEKWALNNHMKLHTGEKPFKCTWPTCHYSFLTASAMKDHYRTHTGEKSFLCDLCGFAGGTRHALTKHRRQHTGEKPFKCDECNFASTTQSHLTRHKRVHTGEKPYRCPWCDYRSNCAENIRKHILHTGKHEGVKMYNCPKCDYGTNVPVEFRNHLKEQHPDIENPDLAYLHAGIVSKSYECRLKGQGATFVETDSPFTAATLAEESPVKEKSLRSSKRQASPPEQVQQVIIIQGYDGEFALDASVEETAAATLQTLAMAGQVARVVHITEHGQVIATSQNGAHVGSVAPGPILQEQLADGATQVVVMGGSMESHGVDEALSPGGAVIQQVTKQEILSLSEASVPPSDTSSALDALLCAVTELGEVENRSGHEEKGRPSHKDVLIQLPSQEAAHAHASTEAEETQLFQDGQESQAAMEVLTQVVRPSAIITSQERAQVAFKKMVQGVLQFAVCDTAAASQLMKDGVTQVIVNEEGAVHMVAGEGSQFIMQDTETHGLRVPAEHVDLVESEGEISQIIVTEELVQAMVRESNSNFPEGATHYIVTELPPGVQEDTGVYSHTVIETASSPEILQAGAALGAEAVGASSTEQLTSMVIYTQDGSPAATVIQSQRENTELQEA", "length": 2233, "header": "tr|A0A8C2N1V9-1|A0A8C2N1V9_CRIGR Isoform 1 of Zinc finger protein 407 isoform X2 OS=Cricetulus griseus OX=10029 GN=Znf407 PE=3 SV=1 CANONICAL=A0A8C2N1V9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N1V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1V9/entry#A0A8C2N1V9-1", "sequence": { "sequence": "MDSDNKHENDEDEEARDMKSISSHDAICGPVSDGIANASENFTNKRGLSESSSLDSVAVEEDRSELASKRMRIEVVEPLEMGEQGTCGLDTVEASVHSAEARKEAFPTISSDGGRALPSDFSPSCDFSMFDTLPLKADAVRKPAQEMSSLVPERHTPFPPEEMSIGCSFGNAESVLKCSMCGHSFSSCSALEKHVECHVEQDKECACCHCSHRAESSSSPPHMHVKHTHGPQKTFSCDLCGFQCAEENLLNAHYLGKTHLRRQNLAARGGFVQILTKQPFPKKACVMGTKNVRTKPRASKPIARNGDSKGVQNTGNKFKDCRGAPSERNGGRSELLVQMVPSRNTSSGKGEIVEENATLGVVQNPENQNKQLGGLVSSEGLLGKSEPIRNTLQIAHISISATSRPRSERNILMLGNSFRRRSGTFTLKGQAKKRYNLLGINKRSASETQRVYMKHFRTQMKTNDTQPVTEQLQRSKDVQSLCVTTSDDPKVMQNKTASCFSDSTQLGSLPVKPASDLQVLCTSPECGHIAADKTDLEIHVKGCHAREMQFHCQTCNYSSPSRKDLEKHLHSNQHQDMTPVLSCQCCSFISLNEMSLRDHMKEKHSMGFFCTSCNLFLSEKDVEEHRATEMHNSLVVQPKMASVSPLSTLESENMDDSREESGKAAKADPTELRVSHGTEARHSSKPQFQCKKCFYKTRSSTVLTRHIKLRHGQDYHFLCKACNLYSLSKEGMEKHIKRSKHLENAKKNNIGLSFEECIERVCIGANDKKEESNSSGSGRPEGHVGVRLQEPFHREQSLLTPKELPQSDVITKDEELALATTPKRGRPKGSISRTCSHCGLLASSITNLTVHIRRKHSHQYSYLCKVCKYYTVTKGDMERHCATKKHKGRVEIEANGKQSSDIIVGPEGGNLEACKKNAPPAVTVSDEQANKSTESDTSTLDKPVVDCASAVEVEAASAFHSVEGEVSSQLSDKRGQMSLETEDLLQQSDACSQRDVAGSGDNKCVHCEFSAHSAASLELHVKRKHTKEFEFYCMACDYYAVTRREMTRHAATEKHKMKRQSYLNSSSADAGSSEMSKSILLSQEEHSQNPEELKITPDQSCGTLKSGNAAGCSVLDENTNLDMSKVLCATDSVEIVPEEDHSFCETLQQPLVKDKSIKPREIVSLSTPSNHGFPDCLQNENPGSSAVDCETAKRKHGMLNDAGDLSTHCEDEGGSADDSARKVPDKTLCSGDLDGGHSAAATSPVVLKIPRDHLHLDGGDQNKVGCEQSSEDFKHVHASVVEKKEVLMNSKHRTESVLEEDGPASDDTVDSNDVYETIISIDDKGQTMYSFGRFDSSIIRIKTCEDGELVDQSEEGLMATGARVSELPLKESAQGLKRRKVEGNSFGESTRIRCDDCGFLADGLSGLNVHIAMKHPTKEKHFHCLLCGKSFYTESNLHQHLASAGHMRNEQASVEELPEGGATFKCVKCTEPFDSEQNLFLHIKGQHEELLREVNKYIVEDTEQINREREENQGNICKYCGKMCRSSNSMAFLAHIRTHTGSKPFKCKICHFATAQLGDARNHVKRHLGMREYKCHVCGVAFVMKKHLNTHLLGKHGVGTPKERKFTCHLCDRSFTEKWALNNHMKLHTGEKPFKCTWPTCHYSFLTASAMKDHYRTHTGEKSFLCDLCGFAGGTRHALTKHRRQHTGEKPFKCDECNFASTTQSHLTRHKRVHTGEKPYRCPWCDYRSNCAENIRKHILHTGKHEGVKMYNCPKCDYGTNVPVEFRNHLKEQHPDIENPDLAYLHAGIVSKSYECRLKGQGATFVETDSPFTAATLAEESPVKEKSLRSSKRQASPPEQVQQVIIIQGYDGEFALDASVEETAAATLQTLAMAGQVARVVHITEHGQVIATSQNGAHVGSVAPGPILQEQLADGATQVVVMGGSMESHGVDEALSPGGAVIQQVTKQEILSLSEASVPPSDTSSALDALLCAVTELGEVENRSGHEEKGRPSHKDVLIQLPSQEAAHAHASTEAEETQLFQDGQESQAAMEVLTQVVRPSAIITSQERAQVAFKKMVQGVLQFAVCDTAAASQLMKDGVTQVIVNEEGAVHMVAGEGSQFIMQDTETHGLRVPAEHVDLVESEGEISQIIVTEELVQAMVRESNSNFPEGATHYIVTELPPGVQEDTGVYSHTVIETASSPEILQAGAALGAEAVGASSTEQLTSMVIYTQDGSPAATVIQSQRENTELQEA", "length": 2233, "header": "tr|A0A8C2N1V9-1|A0A8C2N1V9_CRIGR Isoform 1 of Zinc finger protein 407 isoform X2 OS=Cricetulus griseus OX=10029 GN=Znf407 PE=3 SV=1 CANONICAL=A0A8C2N1V9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GR62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1V9/entry#A0A9J7GR62-1", "sequence": { "sequence": "MDSDNKHENDEDEEARDMKSISSHDAICGPVSDGIANASENFTNKRGLSESSSLDSVAVEEDRSELASKRMRIEVVEPLEMGEQGTCGLDTVEASVHSAEARKEAFPTISSDGGRALPSDFSPSCDFSMFDTLPLKADAVRKPAQEMSSLVPERHTPFPPEEMSIGCSFGNAESVLKCSMCGHSFSSCSALEKHVECHVEQDKECACCHCSHRAESSSSPPHMHVKHTHGPQKTFSCDLCGFQCAEENLLNAHYLGKTHLRRQNLAARGGFVQILTKQPFPKKACVMGTKNVRTKPRASKPIARNGDSKGVQNTGNKFKDCRGAPSERNGGRSELLVQMVPSRNTSSGKGEIVEENATLGVVQNPENQNKQLGGLVSSEGLLGKSEPIRNTLQIAHISISATSRPRSERNILMLGNSFRRRSGTFTLKGQAKKRYNLLGINKRSASETQRVYMKHFRTQMKTNDTQPVTEQLQRSKDVQSLCVTTSDDPKVMQNKTASCFSDSTQLGSLPVKPASDLQVLCTSPECGHIAADKTDLEIHVKGCHAREMQFHCQTCNYSSPSRKDLEKHLHSNQHQDMTPVLSCQCCSFISLNEMSLRDHMKEKHSMGFFCTSCNLFLSEKDVEEHRATEMHNSLVVQPKMASVSPLSTLESENMDDSREESGKAAKADPTELRVSHGTEARHSSKPQFQCKKCFYKTRSSTVLTRHIKLRHGQDYHFLCKACNLYSLSKEGMEKHIKRSKHLENAKKNNIGLSFEECIERVCIGANDKKEESNSSGSGRPEGHVGVRLQEPFHREQSLLTPKELPQSDVITKDEELALATTPKRGRPKGSISRTCSHCGLLASSITNLTVHIRRKHSHQYSYLCKVCKYYTVTKGDMERHCATKKHKGRVEIEANGKQSSDIIVGPEGGNLEACKKNAPPAVTVSDEQANKSTESDTSTLDKPVVDCASAVEVEAASAFHSVEGEVSSQLSDKRGQMSLETEDLLQQSDACSQRDVAGSGDNKCVHCEFSAHSAASLELHVKRKHTKEFEFYCMACDYYAVTRREMTRHAATEKHKMKRQSYLNSSSADAGSSEMSKSILLSQEEHSQNPEELKITPDQSCGTLKSGNAAGCSVLDENTNLDMSKVLCATDSVEIVPEEDHSFCETLQQPLVKDKSIKPREIVSLSTPSNHGFPDCLQNENPGSSAVDCETAKRKHGMLNDAGDLSTHCEDEGGSADDSARKVPDKTLCSGDLDGGHSAAATSPVVLKIPRDHLHLDGGDQNKVGCEQSSEDFKHVHASVVEKKEVLMNSKHRTESVLEEDGPASDDTVDSNDVYETIISIDDKGQTMYSFGRFDSSIIRIKTCEDGELVDQSEEGLMATGARVSELPLKESAQGLKRRKVEGNSFGESTRIRCDDCGFLADGLSGLNVHIAMKHPTKEKHFHCLLCGKSFYTESNLHQHLASAGHMRNEQASVEELPEGGATFKCVKCTEPFDSEQNLFLHIKGQHEELLREVNKYIVEDTEQINREREENQGNICKYCGKMCRSSNSMAFLAHIRTHTGSKPFKCKICHFATAQLGDARNHVKRHLGMREYKCHVCGVAFVMKKHLNTHLLGKHGVGTPKERKFTCHLCDRSFTEKWALNNHMKLHTGEKPFKCTWPTCHYSFLTASAMKDHYRTHTGEKSFLCDLCGFAGGTRHALTKHRRQHTGEKPFKCDECNFASTTQSHLTRHKRVHTGEKPYRCPWCDYRSNCAENIRKHILHTGKHEGVKMYNCPKCDYGTNVPVEFRNHLKEQHPDIENPDLAYLHAEDF", "length": 1790, "header": "tr|A0A9J7GR62-1|A0A9J7GR62_CRIGR Computationally mapped isoform of Zinc finger protein 407 isoform X3 OS=Cricetulus griseus OX=10029 GN=Znf407 PE=3 SV=1 CANONICAL=A0A8C2N1V9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1042, "start_aa": "Thr", "end_pos": 1042, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1042", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 923, "start_aa": "Thr", "end_pos": 923, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr923", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N206-1", "uniprot_ac": "A0A8C2N206", "uniprot_id": "A0A8C2N206_CRIGR", "mass": { "chemical_mass": 79127.0, "monoisotopic_mass": 79127.0 }, "refseq": { "ac": "XP_003503962", "name": "E3 ubiquitin-protein ligase RNF103 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503962" }, "gene_names": [ { "name": "Rnf103", "type": "recommended", "evidence": [ { "id": "A0A8C2N206", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N206" } ] }, { "name": "Rnf103", "type": "synonym", "evidence": [ { "id": "XP_003503962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503962" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase RNF103 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003503962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503962" }, { "id": "A0A8C2N206", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N206/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 474 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614012.1) and transcript sequence (IACG01047914.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003503962", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503962" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N206", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N206" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rnf103", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N206", "locus": {} } ], "crossref": [ { "id": "cd16473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770542", "url": "https://www.ncbi.nlm.nih.gov/gene/100770542", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770542", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770542", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PDWLAWP", "url": "https://omabrowser.org/oma/group/PDWLAWP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N206", "url": "https://www.orthodb.org/?gene=A0A8C2N206", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15302", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15302", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15302:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15302:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003503962", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503962", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N206", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N206", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N206-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N206-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7I4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7I4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7I4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNVEHLKEEWNKSDQYWVKIYLFAKLDQPPAFFSALSIKFTGRVEFIFVNVENWDNKSYMTDIGVYNMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLRLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRSNNDEVNANNLEWLSSLWDWYTSYLFHPIASLQNFPVESDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGVQSEEEMSESSQDTENDSDSDNMDTFSSKDVFEDKQSIVHSSLGRTSHCDAGACSCANKYCQTSPRERKGRSYGSHNTNEDMEPDWLTWPAGTLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPFAQQQLLSNDVPS", "length": 683, "header": "tr|A0A8C2N206-1|A0A8C2N206_CRIGR Isoform 1 of E3 ubiquitin-protein ligase RNF103 isoform X1 OS=Cricetulus griseus OX=10029 GN=Rnf103 PE=4 SV=1 CANONICAL=A0A8C2N206-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N206-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N206/entry#A0A8C2N206-1", "sequence": { "sequence": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNVEHLKEEWNKSDQYWVKIYLFAKLDQPPAFFSALSIKFTGRVEFIFVNVENWDNKSYMTDIGVYNMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLRLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRSNNDEVNANNLEWLSSLWDWYTSYLFHPIASLQNFPVESDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGVQSEEEMSESSQDTENDSDSDNMDTFSSKDVFEDKQSIVHSSLGRTSHCDAGACSCANKYCQTSPRERKGRSYGSHNTNEDMEPDWLTWPAGTLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPFAQQQLLSNDVPS", "length": 683, "header": "tr|A0A8C2N206-1|A0A8C2N206_CRIGR Isoform 1 of E3 ubiquitin-protein ligase RNF103 isoform X1 OS=Cricetulus griseus OX=10029 GN=Rnf103 PE=4 SV=1 CANONICAL=A0A8C2N206-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N206/entry#A0A9J7H7I4-1", "sequence": { "sequence": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRDRHRSGSLEVKTEKWIPGTDRPTSLAFLWSSKPVRDPGSEEKN", "length": 204, "header": "tr|A0A9J7H7I4-1|A0A9J7H7I4_CRIGR Computationally mapped isoform of E3 ubiquitin-protein ligase RNF103 isoform X2 OS=Cricetulus griseus OX=10029 GN=Rnf103 PE=4 SV=1 CANONICAL=A0A8C2N206-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N206", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N206" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N206", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N206" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770542", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770542", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YSH5-1", "protein_name": "Ring finger protein 103", "gene_name": "RNF103", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MWLKLCFLLLYFLVLFVLARVFEAVVWYETGFFATQLVDPVALSFRKLRTILECRGLGHSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKVHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWLKSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNSEHLREEWNRSDQYRVKIYLFASLDQPPAFFSALSVKFTGRVEFIFVNVENWDNKSYMAEIGVYKTPSYILRTPEGIYRYGSNAGEFISLRAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLKLFRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRNNNNDEVNANNLEWLSSLWDWYTSYLFHPIASFQHFPFDSDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPVWRFKCLGVHSDEEMLETLQDGESDSDTENREVFSSEKDISEDDEPSTFHRPRAGEPRSRAGSCSCASTCCHKEPCERKARSYGSYSTADEPDWSAWPPEMLHCTECVVCLENFERGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWASYKKKQPYTHPQPLSSDSPS", "length": 684 }, "evidence": [ { "id": "A0A8C2N206", "url": "https://omabrowser.org/oma/group/A0A8C2N206/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BEJ4-1", "protein_name": "Ring finger protein 103", "gene_name": "RNF103", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNAERLKEEWNKSDQYWVKIYLFANLDQPPAFFSALSIKFTGRVEFIFVNVEKWDNKSYMTDIGVYNMPSYILRTPEGIYRYGNHTGEYISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLKLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRNINNDEVNANNLEWLSSLWDWYTSYLFHPIASFQNFPVESDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGVQSEEEMSEGSQDIENDSDSESTDTLSSEKEVFEDKLSIIHSSPGRASHCDAEACSCANKYCQTSPYERKGRSYGSYSANEDMEPDWLTWPADMLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQHQPLSNDFPS", "length": 685 }, "evidence": [ { "id": "A0A8C2N206", "url": "https://omabrowser.org/oma/group/A0A8C2N206/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SVD1-1", "protein_name": "Ring finger protein 103", "gene_name": "RNF103", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYDAEHLKEEWNKSDQYWVKIYLFANLDQPPAFFSALSIKFTGRVEFIFVNVENWDNKSYMTDIGIYSMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSVQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLKLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRNNNNDEVNANNLEWLSSLWDWYTSYLFHPITSFQNFPVESDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGVQSEEEMSEGSQDTEHESDSESTDTLSSEKEVFEEKQSIVHSSPGQTSHSDAEACSCASKYCQTTAYERKGRSYGSYSSNEDMEPDWLTWPADMLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQHQSLSNDVPS", "length": 685 }, "evidence": [ { "id": "A0A8C2N206", "url": "https://omabrowser.org/oma/group/A0A8C2N206/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O00237-1", "protein_name": "E3 ubiquitin-protein ligase RNF103", "gene_name": "RNF103", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNAEHLKEEWNKSDQYWLKIYLFANLDQPPAFFSALSIKFTGRVEFIFVNVENWDNKSYMTDIGIYNMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLKLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRNNNNDEVNANNLEWLSSLWDWYTSYLFHPIASFQNFPVESDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGVQSEEEMSEGSQDTENDSESENTDTLSSEKEVFEDKQSVLHNSPGTASHCDAEACSCANKYCQTSPCERKGRSYGSYNTNEDMEPDWLTWPADMLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQHQPLSNDVPS", "length": 685 }, "evidence": [ { "id": "A0A8C2N206", "url": "https://omabrowser.org/oma/group/A0A8C2N206/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EPZ8-1", "protein_name": "E3 ubiquitin-protein ligase RNF103", "gene_name": "Rnf103", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNVEHLKEEWNKSDQYWVKIYLFANLDQPPAFFSALSIKFTGRVEFIFVNVENWNNKSYMTDIGIYNMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLRLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRSNNDEVNANNLEWLSSLWDWYTSYLFHPIASFQNFPVDSDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGAQSEEEMSESSQDTENDSDSDNTDTFSSSKDVFEDKQNVHSSPGRTSRCDTEACSCANKCVSSPCERKRRSYGSHNTKEDMEPDWLTWPAGTLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQQQPLSNDAPS", "length": 682 }, "evidence": [ { "id": "A0A8C2N206", "url": "https://omabrowser.org/oma/group/A0A8C2N206/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9R1W3-1", "protein_name": "E3 ubiquitin-protein ligase RNF103", "gene_name": "Rnf103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNVEHLKEEWNKSDQYWVKIYLFANLDQPPAFFSALSIKFTGRVEFIFVNVENWNNKSYMTDIGIYNMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYDYSLRLLRYSNTTTLASWVRADWMFYTSHPALFLSTYLGHGLLIDYFEKKRRRSNNDEVNANNLEWLSSLWDWYTSYLFHPIASFQNFPVDSDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGVQSEEEMSESSQDTENDSDSDNMDTFSSSKDIFEDKQSVVHSSPGRTSHCDTEACSCANKCESSPCERKRRSYGSHNTDEDMEPDWLTWPAGTLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQQQPLSNDVPS", "length": 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"A0A8C2N206", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N206" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N206", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N206" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N206", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N206" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { 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"homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 228, "end_pos": 230 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 301, "end_pos": 303 }, { "start_pos": 398, "end_pos": 400 }, { "start_pos": 536, "end_pos": 538 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N233-1", "uniprot_ac": "A0A8C2N233", "uniprot_id": "A0A8C2N233_CRIGR", "mass": { "chemical_mass": 36733.0, "monoisotopic_mass": 36733.0 }, "refseq": { "ac": "XP_003511844", "name": "mitochondrial mRNA pseudouridine synthase TRUB2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511844" }, "gene_names": [ { "name": "Trub2", "type": "recommended", "evidence": [ { "id": "A0A8C2N233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N233" } ] }, { "name": "Trub2", "type": "synonym", "evidence": [ { "id": "XP_003511844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511844" } ] } ], "protein_names": [ { "name": "Mitochondrial mRNA pseudouridine synthase TRUB2 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2N233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N233/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial mRNA pseudouridine synthase TRUB2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003511844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511844" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615231.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003511844", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511844" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N233", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N233" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Trub2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N233", "locus": {} } ], "crossref": [ { "id": "cd02868", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02868", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766452", "url": "https://www.ncbi.nlm.nih.gov/gene/100766452", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766452", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766452", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHVTARM", "url": "https://omabrowser.org/oma/group/YHVTARM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N233", "url": "https://www.orthodb.org/?gene=A0A8C2N233", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13195", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13195", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13195:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13195:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01509", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01509", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003511844", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511844", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N233", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N233", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N233-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N233-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSSGLARLQGLFAVYKPPGMKWLHARETVELQLLKGLNAAKPPAPEQRVRFLLGPVEGSEEKKLTLTATSVPTLTTHRLVRGPAFTSLKIGVGHHLDARASGVLVLAVGHGLRLLTDVYDAHLTKDYTVRGLLGKATDSFCEDGRLIEKTTYDHVTREMLDRILARIQGSHQKALVMYSNLDLKSQEAYEMAVQGVIRPMNKSPMLITGTRCLHFAPPEFLLEVQCMHETQQQLRKLVHEIGLELKTAAVCTQVRRTRDGFFRLDDALLRTQWNLHSIQGAIQSAAPRVAAELERNLRLRLGHQQLPSAGQPWGSKDPSSTVEVESYSGQ", "length": 331, "header": "tr|A0A8C2N233-1|A0A8C2N233_CRIGR Isoform 1 of Mitochondrial mRNA pseudouridine synthase TRUB2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Trub2 PE=3 SV=1 CANONICAL=A0A8C2N233-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N233-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N233/entry#A0A8C2N233-1", "sequence": { "sequence": "MGSSGLARLQGLFAVYKPPGMKWLHARETVELQLLKGLNAAKPPAPEQRVRFLLGPVEGSEEKKLTLTATSVPTLTTHRLVRGPAFTSLKIGVGHHLDARASGVLVLAVGHGLRLLTDVYDAHLTKDYTVRGLLGKATDSFCEDGRLIEKTTYDHVTREMLDRILARIQGSHQKALVMYSNLDLKSQEAYEMAVQGVIRPMNKSPMLITGTRCLHFAPPEFLLEVQCMHETQQQLRKLVHEIGLELKTAAVCTQVRRTRDGFFRLDDALLRTQWNLHSIQGAIQSAAPRVAAELERNLRLRLGHQQLPSAGQPWGSKDPSSTVEVESYSGQ", "length": 331, "header": "tr|A0A8C2N233-1|A0A8C2N233_CRIGR Isoform 1 of Mitochondrial mRNA pseudouridine synthase TRUB2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Trub2 PE=3 SV=1 CANONICAL=A0A8C2N233-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N233", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N233" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N233", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N233" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766452", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766452", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O95900-1", "protein_name": "Pseudouridylate synthase TRUB2, mitochondrial", "gene_name": "TRUB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSAGLSRLHGLFAVYKPPGLKWKHLRDTVELQLLKGLNARKPPAPKQRVRFLLGPMEGSEEKELTLTATSVPSFINHPLVCGPAFAHLKVGVGHRLDAQASGVLVLGVGHGCRLLTDMYNAHLTKDYTVRGLLGKATDDFREDGRLVEKTTYDHVTREKLDRILAVIQGSHQKALVMYSNLDLKTQEAYEMAVRGLIRPMNKSPMLITGIRCLYFAPPEFLLEVQCMHETQKELRKLVHEIGLELKTTAVCTQVRRTRDGFFTLDSALLRTQWDLTNIQDAIRAATPQVAAELEKSLSPGLDTKQLPSPGWSWDSQGPSSTLGLERGAGQ", "length": 331 }, "evidence": [ { "id": "A0A8C2N233", "url": "https://omabrowser.org/oma/group/A0A8C2N233/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5XFW2-1", "protein_name": "Pseudouridylate synthase TRUB2, mitochondrial", "gene_name": "Trub2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSSGLARLQGLFAVYKPPGLKWLHVRETVELQLLKGLNAQQPSAPEQHVRFLLGPVEGSEEKKLTLTATSVPSLTTHRLVRGPAFRNLKIGVGHRLDVQASGVLVLAVGHGRSLLTDMYDAHLTKDYTVRGLLGKATDNFCEDGQLIEKTTYDHVTRERLDRILAMIQGSHQKALVMYSNLDLKSQEAYERAVQGVIRPMNKSPMLIAGIRCLHFAPPEFLLEVQCMHETQQQLRRLVHEIGLELKTTAVCMQVRRTRDGFFGLDDALLRTQWDLHSIQDAIQTAAPRVARELRKNLSLMSGHQQQLPSAGQPWASRVQAPL", "length": 323 }, "evidence": [ { "id": "A0A8C2N233", "url": "https://omabrowser.org/oma/group/A0A8C2N233/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91WG3-1", "protein_name": "Pseudouridylate synthase TRUB2, mitochondrial", "gene_name": "Trub2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSSGLARLQGLFAVYKPPGLKWLHLRETVELQLLKGLNAQQPPAPDQRVRFLLGPVEGSEEKKLTLRATNVPSLTTHRLVRGPAFTNLKIGVGHRLDVQASGVLVLAVGHGRSLLTDMYDAHLTKDYTVRGLLGKATDNFCEDGRLIEKTTYDHVTRERLDRILAVIQGSHQKALVMYSNLDLKSQEAYEMAVQGVIRPMNKSPMLISGIRCLHFAPPEFLLEVQCMHETQQQLRKLVHEIGLELKTSAVCTQVRRTRDGFFGLDDALLRTQWDLHNIQDAIQAAAPRVAAELQKNLSLKLGHHQLPSTGQPWGLKDPSSTLELESCSGQ", "length": 331 }, "evidence": [ { "id": "A0A8C2N233", "url": "https://omabrowser.org/oma/group/A0A8C2N233/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N233", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N233" } ], "pmid": "" }, { "name": "tRNA pseudouridine(55) synthase activity", "id": "GO:0160148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160148", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N233", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N233" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N233", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N233" } ], "pmid": "" }, { "name": "ribonucleoprotein granule", "id": "GO:0035770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035770", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N233", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N233" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA pseudouridine synthesis", "id": "GO:1990481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990481", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N233", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N233" } ], "pmid": "" }, { "name": 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Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271103", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271103" } ] }, { "annotation": "Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G071", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G071#function" }, { "database": "UniProtKB", "id": "RU367083", "url": "https://www.uniprot.org/uniprotkb/RU367083#function" }, { "database": "UniProtKB", "id": "A0A9J7JR65", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JR65#function" }, { "database": "UniProtKB", "id": "ARBA00055694", "url": "https://www.uniprot.org/uniprotkb/ARBA00055694#function" }, { "database": 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"tr|A0A8C2N239-1|A0A8C2N239_CRIGR Isoform 1 of CCR4-NOT transcription complex subunit 10 OS=Cricetulus griseus OX=10029 GN=Cnot10 PE=3 SV=1 CANONICAL=A0A8C2N239-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G071-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N239/entry#A0A9J7G071-1", "sequence": { "sequence": 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griseus OX=10029 GN=Cnot10 PE=3 SV=1 CANONICAL=A0A8C2N239-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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assembly gap :: added 1284 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613890.1) and transcript sequences (IACG01019049.1 and IACG01019084.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502371", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502371" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dusp15", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5", "locus": {} } ], "crossref": [ { "id": "100755376", "url": "https://www.ncbi.nlm.nih.gov/gene/100755376", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755376", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755376", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YIMAVTE", "url": "https://omabrowser.org/oma/group/YIMAVTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N2E5", "url": "https://www.orthodb.org/?gene=A0A8C2N2E5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45948", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45948", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45948:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45948:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502371", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502371", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N2E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N2E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNGMTKVLPGLYLGNFIDAKDPDQLGRNKITHIISIHESPQPQLQGIKYLRISVADAPEVPIKKHFKECINFIHSCRLNGGNCLVHCFAGISRSTTIVVAYVMTVTGLGWREVLEAIKANRPIANPNPGFRQQLEEFGWGNSQKLRRQLEERFGESLFRDQEELRTLLPLYRRCRQGSATSATSATASAAASEGTLQRLMPRSPRDAHRPLPLLARVKQTFSCLPRCLSRKGGK", "length": 235, "header": "tr|A0A8C2N2E5-1|A0A8C2N2E5_CRIGR Isoform 1 of Dual specificity protein phosphatase 15 OS=Cricetulus griseus OX=10029 GN=Dusp15 PE=3 SV=1 CANONICAL=A0A8C2N2E5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N2E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5/entry#A0A8C2N2E5-1", "sequence": { "sequence": "MGNGMTKVLPGLYLGNFIDAKDPDQLGRNKITHIISIHESPQPQLQGIKYLRISVADAPEVPIKKHFKECINFIHSCRLNGGNCLVHCFAGISRSTTIVVAYVMTVTGLGWREVLEAIKANRPIANPNPGFRQQLEEFGWGNSQKLRRQLEERFGESLFRDQEELRTLLPLYRRCRQGSATSATSATASAAASEGTLQRLMPRSPRDAHRPLPLLARVKQTFSCLPRCLSRKGGK", "length": 235, "header": "tr|A0A8C2N2E5-1|A0A8C2N2E5_CRIGR Isoform 1 of Dual specificity protein phosphatase 15 OS=Cricetulus griseus OX=10029 GN=Dusp15 PE=3 SV=1 CANONICAL=A0A8C2N2E5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755376", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755376", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B4F7B7-1", "protein_name": "Dual specificity protein phosphatase 15", "gene_name": "Dusp15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNGMTKVLPGLYLGNFIDAKDPDQLGRNKITHIVSIHESPQPLLQDITYLRISVSDTPEVPIKKHFKECVHFIHSCRLNGGNCLVHCFAGISRSTTVVIAYVMTVTGLGWQEVLEAIKASRPIANPNPGFRQQLEEFGWANSQKLRRQLEERFGEIPFRDEEDLRALLPLCRRCRQGPGTSAPSATTASSAASEGTLQRLVPRSPRESHRPLPLLARVKQTFFCLPRCLSRKGGK", "length": 236 }, "evidence": [ { "id": "A0A8C2N2E5", "url": "https://omabrowser.org/oma/group/A0A8C2N2E5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BRQ8-1", "protein_name": "Dual specificity protein phosphatase 15", "gene_name": "DUSP15", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGNGMSKILPGLYLGNFIDAKDLEQLSRNKITHIVSIHESPQPLLQDITYLRIPLPDTPEASIKKHFKECISFIHQCRLQGGNCLVHCLAGISRSTTIVVAYVMAVTEMSSQEVLEAIRSVRPVANPNPGFKQQLEEFSGSAARKMRRHLKQRYGTSPFNDEEEIKALLPVGRGRASRAEGARQGLVPRARDIKSTAPFLLRVKRTFSCIPACLK", "length": 215 }, "evidence": [ { "id": "A0A8C2N2E5", "url": "https://omabrowser.org/oma/group/A0A8C2N2E5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1S5P8-1", "protein_name": "Dual specificity protein phosphatase 15", "gene_name": "DUSP15", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNGMTKVLPGLYLGNFIDAKDTDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWGNSRKLRRQLEERFGESPFRDEEEVRALLPLCKRCRQGSASAAASPAPNSSASEGTLQRLVPRMPRETHRPLPLLARVKQTFSCLPRCLSRKGGK", "length": 235 }, "evidence": [ { "id": "A0A8C2N2E5", "url": "https://omabrowser.org/oma/group/A0A8C2N2E5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8R4V2-1", "protein_name": "Dual specificity protein phosphatase 15", "gene_name": "Dusp15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNGMTKVLPGLYLGNFIDAKDPDQLGRNKITHIISIHESPQPLLQDITYLRISVSDTPEVPIKKHFKECVHFIHSCRLNGGNCLVHCFAGISRSTTIVIAYVMTVTGLGWQEVLEAIKASRPIANPNPGFRQQLEEFGWANSQKLRRQLEERFGEIPFRDEEDLRALLPLCRRCRQGSATSAASATTASSAAEGTLQRLVPRSPRDSHQPLPLLARVKQTFFCLPRCLSRKGGK", "length": 235 }, "evidence": [ { "id": "A0A8C2N2E5", "url": "https://omabrowser.org/oma/group/A0A8C2N2E5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H1R2-1", "protein_name": "Dual specificity protein phosphatase 15", "gene_name": "DUSP15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEGVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWASSQKGARHRTSKTSGAQCPPMTSATCLLAARVALLSAALVREATGRTAQRCRLSPRAAAERLLGPPPHVAAGWSPDPKYQICLCFGEEDPGPTQHPKEQLIMADVQVQLRPGSSSCTLSASTERPDGSSTPGNPDGITHLQCSCLHPKRAASSSCTR", "length": 295 }, "evidence": [ { "id": "A0A8C2N2E5", "url": "https://omabrowser.org/oma/group/A0A8C2N2E5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ], "pmid": "" }, { "name": "regulation of oligodendrocyte differentiation", "id": "GO:0048713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048713", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ], "pmid": "" }, { "name": "protein tyrosine/serine/threonine phosphatase activity", "id": "GO:0008138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008138", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3H060-1", "G3H622-1", "G3H9Q0-1", "A0A8C2LH05-1", "G3HKY7-1", "G3GWQ6-1", "G3HBF6-1", "G3GRD1-1", "G3H8H2-1", "A0A9J7FG56-1", "A0A061IAM9-1", "A0A9J7GE78-1", "A0A9J7GZK0-1", "A0A061HX98-1", "A0A061HZS8-1", "A0A3L7HEJ5-1", "A0A8C2LYZ8-1", "A0A9J7JC04-1", "A0A8C2MQ28-1", "A0A3L7I231-1", "A0A9J7EY47-1", "A0A8C2LVB9-1", "A0A8C2MZ43-1", "A0A9J7G003-1", "A0A8C2QC02-1", "A0A9J7JD11-1", "A0A8C2QH88-1", "A0A9J7EXY7-1", "A0A9J7JC62-1", "A0A9J7FEN1-1", "A0A9J7FB56-1", "A0A9J7FEZ5-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FWX7-1", "A0A9J7G1A0-1", "A0A9J7JTT7-1", "A0A9J7G7L1-1", "A0A9J7G7K2-1", "A0A9J7GNR2-1", "A0A9J7JU39-1", "A0A9J7KAX8-1", "A0A9J7GQG9-1", "A0A9J7GX92-1", "A0A9J7F2A0-1", "A0A9J7EZC9-1", "A0A9J7EZL1-1", "A0A9J7FIV0-1", "A0A8C2MFV5-1", "A0A8C2N2E5-1", "A0A8C2N686-1", "A0A8C2QCP2-1", "A0A3L7IA07-1", "A0A9J7FYL8-1", "A0A9J7G168-1", "A0A9J7GBQ5-1", "A0A9J7H7L7-1", "A0A9J7HBK7-1", "A0A9J7GQC8-1", "A0A9J7H152-1", "A0A9J7KDA7-1", "A0A9J7KDM0-1", "A0A9J7J766-1", "A0A9J7FKB3-1", "A0A3L7HAL2-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GV48-1", "G3GWQ6-1", "G3H060-1", "G3H9Q0-1", "G3H7Z6-1", "G3I157-1", "G3HCQ6-1", "A0A8C2MA30-1", "G3HMJ7-1", "G3I434-1", "G3H622-1", "G3HKY7-1", "G3GRD1-1", "G3I4H5-1", "G3H8H2-1", "A0A9J7F890-1", "A0A8C2MW37-1", "A0A061I6V7-1", "A0A9J7GBP5-1", "A0A9J7JFN8-1", "A0A9J7G7W0-1", "A0A9J7GE78-1", "A0A061HVT3-1", "A0A061HX98-1", "A0A3L7HX32-1", "A0A8C2LYQ8-1", "A0A8C2M5N0-1", "A0A9J7JBH1-1", "A0A9J7EY47-1", "A0A8C2LGL9-1", "A0A8C2LVB9-1", "A0A8C2QH88-1", "A0A9J7F130-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FXD0-1", "A0A9J7G243-1", "A0A9J7GEM4-1", "A0A9J7G1B8-1", "A0A9J7K1J8-1", "A0A9J7K5S1-1", "A0A9J7EZL1-1", "A0A8C2QCP2-1", "A0A8C2LTP5-1", "A0A8C2N2E5-1", "A0A8C2QBZ1-1", "A0A3L7HBF4-1", "A0A9J7GK96-1", "A0A8C2LI03-1", "A0A9J7G0U7-1", "A0A9J7GD33-1", "A0A9J7H9S5-1", "A0A9J7HCJ8-1", "A0A9J7GJY7-1", "A0A9J7JYW1-1", "A0A3L7I513-1", "A0A9J7FKB3-1", "A0A8C2LGY1-1", "A0A3L7HEM4-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GV48-1", "G3GWQ6-1", "G3H060-1", "G3H9Q0-1", "G3H622-1", "G3HKY7-1", "G3H7Z6-1", "G3I157-1", "G3HCQ6-1", "A0A8C2MA30-1", "G3HMJ7-1", "A0A8C2MF90-1", "A0A9J7GX39-1", "G3I434-1", "G3GRD1-1", "G3I4H5-1", "G3H8H2-1", "A0A9J7F890-1", "A0A8C2MW37-1", "A0A061I6V7-1", "A0A9J7GBP5-1", "A0A9J7JFN8-1", "A0A9J7G7W0-1", "A0A9J7GE78-1", "A0A061HX98-1", "A0A3L7HEJ5-1", "A0A3L7HX32-1", "A0A8C2LYQ8-1", "A0A8C2M5N0-1", "A0A9J7JBH1-1", "A0A8C2ME51-1", "A0A8C2MTQ0-1", "A0A3L7IJ01-1", "A0A9J7EY47-1", "A0A8C2LGL9-1", "A0A8C2LVB9-1", "A0A8C2QH88-1", "A0A9J7F130-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FXD0-1", "A0A9J7G243-1", "A0A9J7GEM4-1", "A0A9J7G1B8-1", "A0A9J7K1J8-1", "A0A9J7K5S1-1", "A0A9J7EZL1-1", "A0A9J7F6Q7-1", "A0A8C2N2E5-1", "A0A8C2LTP5-1", "A0A8C2QBZ1-1", "A0A8C2QCP2-1", "A0A3L7HBF4-1", "A0A3L7HC66-1", "A0A9J7GK96-1", "A0A8C2LI03-1", "A0A9J7G0U7-1", "A0A9J7GD33-1", "A0A9J7H9S5-1", "A0A9J7HCJ8-1", "A0A9J7GJY7-1", "A0A9J7JXQ8-1", "A0A9J7JYW1-1", "A0A9J7FKB3-1", "A0A8C2LGY1-1", "A0A3L7HEM4-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HVT3", "gene_name": "Ppm1k", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.52", "activity": "O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + H2O = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.52", "activity": "", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] } ] }, { "uniprot_ac": "A0A061HX98", "gene_name": "Dusp9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] } ] }, { "uniprot_ac": "A0A061HZS8", "gene_name": "Ptpn14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HZS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZS8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HZS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZS8" } ] } ] }, { "uniprot_ac": "A0A061I6V7", "gene_name": "Pgam5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061I6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6V7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061I6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6V7" } ] } ] }, { "uniprot_ac": "A0A061IAM9", "gene_name": "LOC100766206", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] } ] }, { "uniprot_ac": "A0A3L7HAL2", "gene_name": "Pgp", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] } ] }, { "uniprot_ac": "A0A3L7HBF4", "gene_name": "Cpped1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBF4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBF4" } ] } ] }, { "uniprot_ac": "A0A3L7HC66", "gene_name": "Ppp6c", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HC66" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HC66" } ] } ] }, { "uniprot_ac": "A0A3L7HEJ5", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] } ] }, { "uniprot_ac": "A0A3L7HEM4", "gene_name": "Ctdspl2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEM4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEM4" } ] } ] }, { "uniprot_ac": "A0A3L7HX32", "gene_name": "Dusp8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] } ] }, { "uniprot_ac": "A0A3L7I231", "gene_name": "Ptp4a3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] } ] }, { "uniprot_ac": "A0A3L7I513", "gene_name": "Pdxp", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] } ] }, { "uniprot_ac": "A0A3L7IA07", "gene_name": "Ptp4a2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] } ] }, { "uniprot_ac": "A0A3L7IJ01", "gene_name": "Ppp2cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7IJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJ01" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7IJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJ01" } ] } ] }, { "uniprot_ac": "A0A8C2LGL9", "gene_name": "Ppp1cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LGL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGL9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LGL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGL9" } ] } ] }, { "uniprot_ac": "A0A8C2LGY1", "gene_name": "Ppp1ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LGY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGY1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LGY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGY1" } ] } ] }, { "uniprot_ac": "A0A8C2LH05", "gene_name": "Acp1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] } ] }, { "uniprot_ac": "A0A8C2LI03", "gene_name": "Ctdsp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI03" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI03" } ] } ] }, { "uniprot_ac": "A0A8C2LTP5", "gene_name": "LOC100752571", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LTP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTP5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LTP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTP5" } ] } ] }, { "uniprot_ac": "A0A8C2LVB9", "gene_name": "Dusp22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] } ] }, { "uniprot_ac": "A0A8C2LYQ8", "gene_name": "Ppm1l", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LYZ8", "gene_name": "Ptprf", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] } ] }, { "uniprot_ac": "A0A8C2M5N0", "gene_name": "Ppp1cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2M5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5N0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2M5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5N0" } ] } ] }, { "uniprot_ac": "A0A8C2MA30", "gene_name": "Phlpp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MA30" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MA30" } ] } ] }, { "uniprot_ac": "A0A8C2ME51", "gene_name": "Ppm1g", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2ME51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ME51" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2ME51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ME51" } ] } ] }, { "uniprot_ac": "A0A8C2MF90", "gene_name": "Ssh2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] } ] }, { "uniprot_ac": "A0A8C2MTQ0", "gene_name": "Ssh1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTQ0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTQ0" } ] } ] }, { "uniprot_ac": "A0A8C2MW37", "gene_name": "Ppp3cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ] } ] }, { "uniprot_ac": "A0A8C2MZ43", "gene_name": "Ptprg", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] } ] }, { "uniprot_ac": "A0A8C2N2E5", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": 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{ "uniprot_ac": "A0A8C2QBZ1", "gene_name": "Ctdspl", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QBZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QBZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ] } ] }, { "uniprot_ac": "A0A8C2QC02", "gene_name": "Ptpn6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] } ] }, { "uniprot_ac": "A0A8C2QCP2", "gene_name": "Dusp28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] } ] }, { "uniprot_ac": "A0A8C2QH88", "gene_name": "Dusp12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] } ] }, { "uniprot_ac": "A0A9J7EXY7", "gene_name": "Ptpn13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] } ] }, { "uniprot_ac": "A0A9J7EY47", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] } ] }, { "uniprot_ac": "A0A9J7EZC9", "gene_name": "Ptpn18", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] } ] }, { "uniprot_ac": "A0A9J7EZL1", "gene_name": "LOC113830718", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": 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"O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7F2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2A0" } ] } ] }, { "uniprot_ac": "A0A9J7F6Q7", "gene_name": "LOC103164195", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F6Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6Q7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F6Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6Q7" } ] } ] }, { "uniprot_ac": "A0A9J7F890", "gene_name": "Ctdsp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F890" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F890" } ] } ] }, { "uniprot_ac": "A0A9J7FB56", "gene_name": "Ptpru", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FB56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FB56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB56" } ] } ] }, { "uniprot_ac": "A0A9J7FEN1", "gene_name": "Eya1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] } ] }, { "uniprot_ac": "A0A9J7FIV0", "gene_name": "LOC100763249", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] } ] }, { "uniprot_ac": "A0A9J7FKB3", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] } ] }, { "uniprot_ac": "A0A9J7FMB0", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] } ] }, { "uniprot_ac": "A0A9J7FWJ6", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FWX7", "gene_name": "LOC103158664", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] } ] }, { "uniprot_ac": "A0A9J7FXD0", "gene_name": "Ppm1f", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXD0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXD0" } ] } ] }, { "uniprot_ac": "A0A9J7FYL8", "gene_name": "Ptpn11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] } ] }, { "uniprot_ac": "A0A9J7G003", "gene_name": "Ptprs", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G003" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G003" } ] } ] }, { "uniprot_ac": "A0A9J7G0U7", "gene_name": "Pptc7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ] } ] }, { "uniprot_ac": "A0A9J7G168", "gene_name": "LOC100762307", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ] } ] }, { "uniprot_ac": "A0A9J7G1A0", "gene_name": "Ptpn4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] } ] }, { "uniprot_ac": "A0A9J7G1B8", "gene_name": "Phlpp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B8" } ] } ] }, { "uniprot_ac": "A0A9J7G243", "gene_name": "Ppm1a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G243" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G243" } ] } ] }, { "uniprot_ac": "A0A9J7G7K2", "gene_name": "Ptpn1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] } ] }, { "uniprot_ac": "A0A9J7G7L1", "gene_name": "Ptprj", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] } ] }, { "uniprot_ac": "A0A9J7G7W0", "gene_name": "Ptpmt1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.27", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] } ] }, { 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"activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GD33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GD33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ] } ] }, { "uniprot_ac": "A0A9J7GE78", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] } ] }, { "uniprot_ac": "A0A9J7GEM4", "gene_name": "Ppm1e", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEM4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEM4" } ] } ] }, { "uniprot_ac": "A0A9J7GJY7", "gene_name": "Ppef1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GJY7", "database": 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{ "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] } ] }, { "uniprot_ac": "A0A9J7GX39", "gene_name": "Ssh3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GX39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX39" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GX39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX39" } ] } ] }, { "uniprot_ac": "A0A9J7GX92", "gene_name": "Ptpre", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX92" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX92" } ] } ] }, { "uniprot_ac": "A0A9J7GZK0", "gene_name": "Ptprc", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZK0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZK0" } ] } ] }, { "uniprot_ac": "A0A9J7H152", "gene_name": "Ptprt", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H152" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7H152", "database": "UniProtKB", "url": 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"Ptpn20", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7J766", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J766" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7J766", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J766" } ] } ] }, { "uniprot_ac": "A0A9J7JBH1", "gene_name": "Cdc14a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] } ] }, { "uniprot_ac": "A0A9J7JC04", "gene_name": "Eya3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JC04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC04" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JC04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC04" } ] } ] }, { "uniprot_ac": "A0A9J7JC62", "gene_name": "Tns2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC62" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC62" } ] } ] }, { "uniprot_ac": "A0A9J7JD11", "gene_name": "Ptprm", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JD11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD11" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JD11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD11" } ] } ] }, { "uniprot_ac": "A0A9J7JFN8", "gene_name": "Epm2a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": 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} ] } ] }, { "uniprot_ac": "A0A9J7K5S1", "gene_name": "Ilkap", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7K5S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7K5S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S1" } ] } ] }, { "uniprot_ac": "A0A9J7KAX8", "gene_name": "Eya2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7KAX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAX8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7KAX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAX8" } ] } ] }, { "uniprot_ac": "A0A9J7KDA7", "gene_name": "Ptprb", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7KDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7KDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ] } ] }, { "uniprot_ac": "A0A9J7KDM0", "gene_name": "LOC100769324", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7KDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7KDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ] } ] }, { "uniprot_ac": "G3GRD1", "gene_name": "Dusp10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] } ] }, { "uniprot_ac": "G3GV48", "gene_name": "Ppm1b", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3GV48", "database": "UniProtKB", "url": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027258722", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258722" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2I3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2I3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc18b1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2I3", "locus": {} } ], "crossref": [ { "id": "cd17385", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17385", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100775093", "url": "https://www.ncbi.nlm.nih.gov/gene/100775093", "database": "GeneID", "categories": [ "Genome 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"MIGMIFGCYALFELLASLVFGKYLVQIGAKFMFIAGMFISGGVTILFGVLDQLPEGPIFIVMCFLVRIVDAIGFGAAITASSSILAKAFPNNVATVLGSLEVFSGLGLIAGPPLGGFLYQSFGYEVPFILLGCIVLLMIPLNLWILPSYESDPGEHSFWKLVTLPKVCLIAFVIISLSSCFGFLDPTLSLFVLEKFNLPAGYVGLVFLGLALSYTISSPLFGLLSDRMPNLRKWFLVFGNLITAACYLLLGPVPILHIKSQLWLLVLVLVVNGFSAGMSIIPTFPEMLSCAYENGFEEGISTLGLISGLVSAMWSVGAFMGPMLGGFLYEKIGFEWAAALQGLWALISGLAMGLFYLWEHSKTRRSRSKAQNLIGTEEEQTALLPNET", "length": 388, "header": "tr|A0A9J7JAJ9-1|A0A9J7JAJ9_CRIGR Computationally mapped isoform of MFS-type transporter SLC18B1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Slc18b1 PE=3 SV=1 CANONICAL=A0A8C2N2I3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FGR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGR2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003616289.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027241152", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241152" } ] }, { "annotation": "Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2N9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2N9#function" }, { "database": "UniProtKB", "id": "PIRNR037825", "url": "https://www.uniprot.org/uniprotkb/PIRNR037825#function" }, { "database": "UniProtKB", "id": "ARBA00093346", "url": "https://www.uniprot.org/uniprotkb/ARBA00093346#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2N9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2N9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pde6d", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2N9", "locus": {} } ], "crossref": [ { "id": "100762580", "url": "https://www.ncbi.nlm.nih.gov/gene/100762580", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762580", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762580", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "STNTWQN", "url": "https://omabrowser.org/oma/group/STNTWQN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N2N9", "url": "https://www.orthodb.org/?gene=A0A8C2N2N9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12976", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12976", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12976:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12976:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05351", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05351", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027241152", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241152", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N2N9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N2N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2N9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVV6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAKDERARDILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSAEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV", "length": 150, "header": "tr|A0A8C2N2N9-1|A0A8C2N2N9_CRIGR Isoform 1 of Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta OS=Cricetulus griseus OX=10029 GN=Pde6d PE=3 SV=1 CANONICAL=A0A8C2N2N9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N2N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2N9/entry#A0A8C2N2N9-1", "sequence": { "sequence": "MSAKDERARDILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSAEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV", "length": 150, "header": "tr|A0A8C2N2N9-1|A0A8C2N2N9_CRIGR Isoform 1 of Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta OS=Cricetulus griseus OX=10029 GN=Pde6d PE=3 SV=1 CANONICAL=A0A8C2N2N9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GVV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2N9/entry#A0A9J7GVV6-1", "sequence": { "sequence": "MEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV", "length": 80, "header": "tr|A0A9J7GVV6-1|A0A9J7GVV6_CRIGR Computationally mapped isoform of Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta isoform X2 OS=Cricetulus griseus OX=10029 GN=Pde6d PE=3 SV=1 CANONICAL=A0A8C2N2N9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2N9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2N9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2N9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2N9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762580", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762580", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5P2A3-1", "protein_name": "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "gene_name": "PDE6D", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSATDERAKEILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSAEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMSANVLTGNVIIETKFYDDDLLVSTSRVRLFYV", "length": 150 }, "evidence": [ { "id": "A0A8C2N2N9", "url": "https://omabrowser.org/oma/group/A0A8C2N2N9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A480V9G7-1", "protein_name": "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "gene_name": "PDE6D", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSAKDERAKEILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSAEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV", "length": 150 }, "evidence": [ { "id": "A0A8C2N2N9", "url": "https://omabrowser.org/oma/group/A0A8C2N2N9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZRD3-1", "protein_name": "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "gene_name": "Pde6d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAKDERARDILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSAEQMEKFRLEQKVFFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSKVRLFYV", "length": 150 }, "evidence": [ { "id": "A0A8C2N2N9", "url": "https://omabrowser.org/oma/group/A0A8C2N2N9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43924-1", "protein_name": "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "gene_name": "PDE6D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV", "length": 150 }, "evidence": [ { "id": "A0A8C2N2N9", "url": "https://omabrowser.org/oma/group/A0A8C2N2N9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O55057-1", "protein_name": "Retinal rod rhodopsin-sensitive cGMP 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"glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9VLJ0-1", "protein_name": "Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta", "gene_name": "PrBP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGSDDQSAGDRIQKGFQINYMILRDADSGKIIWQENKDFSAPDQEHEARVPVKILDMRAVSREINFSTIESMENFRLDQKVLFKGRIMEEWFFEMGFVGANTTNTWQSTIEAAPESQMMPAKVLNGNVTIQTSFYDNETLITKSVVRLYYI", "length": 151 }, "evidence": [ { "id": "A0A8C2N2N9", "url": "https://omabrowser.org/oma/group/A0A8C2N2N9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2N9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2N9" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280776", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280776" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2R0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2R0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Hs3st6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2R0", "locus": {} } ], "crossref": [ { "id": "100766299", "url": "https://www.ncbi.nlm.nih.gov/gene/100766299", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766299", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766299", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N2R0", "url": "https://www.orthodb.org/?gene=A0A8C2N2R0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10605", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10605", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10605:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10605:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280776", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280776", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N2R0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N2R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2R0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGSGGLGGGAGDLQGAGPGQGTALRAPRAPLALVALLLGTYCLFALPGRCPPVARTPAPVPAPAEPPYASRRLGASGLPVASGPGRRRFPQALIVGVKKGGTRALLEFLRLHPDVRALGSEPHFFDRCYDRGLAWYRGLMPRTLDGQITMEKTPSYFVTQEAPRRIHNMSPDTKLIVVVRNPVTRAISDYAQTLSKTPGLPSFRALAFRHGLGPVDTAWSAVRIGLYAQHLDNWLRYFPLSHFLFVSGERLVADPAGEVGRVQDFLGLKRVVTDKHFYFNATKGFPCLKKAQGSGRPRCLGKSKGRPHPRVPEAVVQRLQAFYRPFNRKFYQMTGQDFGWD", "length": 342, "header": "tr|A0A8C2N2R0-1|A0A8C2N2R0_CRIGR Isoform 1 of Sulfotransferase OS=Cricetulus griseus OX=10029 GN=Hs3st6 PE=3 SV=1 CANONICAL=A0A8C2N2R0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N2R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2R0/entry#A0A8C2N2R0-1", "sequence": { "sequence": "MAGSGGLGGGAGDLQGAGPGQGTALRAPRAPLALVALLLGTYCLFALPGRCPPVARTPAPVPAPAEPPYASRRLGASGLPVASGPGRRRFPQALIVGVKKGGTRALLEFLRLHPDVRALGSEPHFFDRCYDRGLAWYRGLMPRTLDGQITMEKTPSYFVTQEAPRRIHNMSPDTKLIVVVRNPVTRAISDYAQTLSKTPGLPSFRALAFRHGLGPVDTAWSAVRIGLYAQHLDNWLRYFPLSHFLFVSGERLVADPAGEVGRVQDFLGLKRVVTDKHFYFNATKGFPCLKKAQGSGRPRCLGKSKGRPHPRVPEAVVQRLQAFYRPFNRKFYQMTGQDFGWD", "length": 342, "header": "tr|A0A8C2N2R0-1|A0A8C2N2R0_CRIGR Isoform 1 of Sulfotransferase OS=Cricetulus griseus OX=10029 GN=Hs3st6 PE=3 SV=1 CANONICAL=A0A8C2N2R0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"MVNREINVCQQTWALLCKNLLRKRRMKRDTFLEFLYTSIILFSLSLTTEIHEVYDFSHLPNVDLGRIDSFNDSNFMIAYTPVTHTTQGIMDKVSLASYMAGITVLGFPDEENMTELVSSRYHDVVRVIFTNTYSYHLKFHTGTRMPSKKEHGDHTAHCSTYEDNINCGISHFWTEGFVALQAAINSAIIEVTTNHSVVEEMMSVTGKYMKIDTFIGQGGVVTDSFLVFCIICFSPLAYYISAGVTRERKKMKGLMTVMGLQDSAFWLSWGLLYGAIIFVVSLLLTFIIKLVQFVILTGFMAIFSLFFFYGLSLISLSFLMSVLLRKSFLTDFVVFFLTVFCGSLGFAALYRILPGSLEWVLSLLSPFAFMLGMAQLLHLDYDVNSNADPTGNPNVIIATIFMLFFDSVFYLVLTFYFEKVLPSEYGQRHSPLFFLKPSFWSQQNQVLDYEIDSEFLDDSFEPVSSDFHGQEAIRIRNLTKEYTERSKRTEALADLSLDIYKGQITAILGHSGAGKSTLLNILSGLCAPTKGWVTIYNNKLSEKTDLESIIKLTGVCPQCNVQFDFLTVRENLRLFAKIKGIRKHEVDNEVQRVLMELEMKNIQDTLAQNLSGGQKRKLTFGIAILGDPQIFLLDEPTAGLDPFTRHRVWNLLKERKAGRVVLFSTQFMDEADILADRKVFISKGKLKCAGSSLFLKKKWGIGYHLSLQLNETCVPERITSLIKQHIPDSKLSAESEGKLSYILPLERTNKFPDLCRDLERCPDLGIENCGVSITTLSEVFLKLEGKSTIDQSDLGMSEDVQTERTRGTGRPTEMEQLVSLLTEKTNMKVGLALWWQQLCAVARLRFRKLKHERKSFVFLILILGIGLLHILSANIGMIARVSDYCWELSPHMYFLTPGQQPHEPLTNLLIINKTGAQIDDFIHSLEKQNISLEIDAFGTRNGTEETLYNGAIILSGGENSFKFTLACHTKRLNCFPVLVDIVSNGLLGLFTPSAHIQTDRSTFPEDDTRGPFDYVPYFISWILFMAFVPPYISMTSIDDYKNGVQLQLWISGLCPSAYWFGQALVEVPIYYILSLSMCVAFYASAPQETMLTTKDLLFQILYVGGYAMSIIFMTYVISFLFRKGRKNSGIWSFCFYIVALCSILLIFTDYFLDDLLFCIIALIPPATLVGCTMLHFQYCALCDIGLEEATSDYTFLLFLVSFLHFAIFLVILRCLESKLGMKTMRMDPVFRISPRTDRVFNNPEEPEGEDEDVRLERERTANALTSVDFQEKPAIIASCLRKEYKGKKKCFVPKSKKKLATRNISFCVRKGEVVGLLGHNGAGKSTSIKIITGEAKPSAGQVLMKGSSRGDTLGFLGYCPQENALWPNLLVREHLEIFAAVKGMSKGDAAVAIARLADALKLQDQMRAPVKTLSEGVKRKLCFALSILGNPSVVLLDEPSTGMDPEGQQQMWQAIQATFTNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKFGKDYLLEMKVRIPAQVEALNAEIKRLFPQAARQERYSSLMVYKLPREDVQPLSQAFFKLETVKQSFDLEEYSLSQSTLEQVFLELSKEQELDCFEDELDPSVQWKLLPQEEA", "length": 1616, "header": "tr|A0A8C2N2S2-1|A0A8C2N2S2_CRIGR Isoform 1 of ATP-binding cassette sub-family A member 8-A OS=Cricetulus griseus OX=10029 GN=LOC100773221 PE=3 SV=1 CANONICAL=A0A8C2N2S2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N2S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2S2/entry#A0A8C2N2S2-1", "sequence": { "sequence": "MVNREINVCQQTWALLCKNLLRKRRMKRDTFLEFLYTSIILFSLSLTTEIHEVYDFSHLPNVDLGRIDSFNDSNFMIAYTPVTHTTQGIMDKVSLASYMAGITVLGFPDEENMTELVSSRYHDVVRVIFTNTYSYHLKFHTGTRMPSKKEHGDHTAHCSTYEDNINCGISHFWTEGFVALQAAINSAIIEVTTNHSVVEEMMSVTGKYMKIDTFIGQGGVVTDSFLVFCIICFSPLAYYISAGVTRERKKMKGLMTVMGLQDSAFWLSWGLLYGAIIFVVSLLLTFIIKLVQFVILTGFMAIFSLFFFYGLSLISLSFLMSVLLRKSFLTDFVVFFLTVFCGSLGFAALYRILPGSLEWVLSLLSPFAFMLGMAQLLHLDYDVNSNADPTGNPNVIIATIFMLFFDSVFYLVLTFYFEKVLPSEYGQRHSPLFFLKPSFWSQQNQVLDYEIDSEFLDDSFEPVSSDFHGQEAIRIRNLTKEYTERSKRTEALADLSLDIYKGQITAILGHSGAGKSTLLNILSGLCAPTKGWVTIYNNKLSEKTDLESIIKLTGVCPQCNVQFDFLTVRENLRLFAKIKGIRKHEVDNEVQRVLMELEMKNIQDTLAQNLSGGQKRKLTFGIAILGDPQIFLLDEPTAGLDPFTRHRVWNLLKERKAGRVVLFSTQFMDEADILADRKVFISKGKLKCAGSSLFLKKKWGIGYHLSLQLNETCVPERITSLIKQHIPDSKLSAESEGKLSYILPLERTNKFPDLCRDLERCPDLGIENCGVSITTLSEVFLKLEGKSTIDQSDLGMSEDVQTERTRGTGRPTEMEQLVSLLTEKTNMKVGLALWWQQLCAVARLRFRKLKHERKSFVFLILILGIGLLHILSANIGMIARVSDYCWELSPHMYFLTPGQQPHEPLTNLLIINKTGAQIDDFIHSLEKQNISLEIDAFGTRNGTEETLYNGAIILSGGENSFKFTLACHTKRLNCFPVLVDIVSNGLLGLFTPSAHIQTDRSTFPEDDTRGPFDYVPYFISWILFMAFVPPYISMTSIDDYKNGVQLQLWISGLCPSAYWFGQALVEVPIYYILSLSMCVAFYASAPQETMLTTKDLLFQILYVGGYAMSIIFMTYVISFLFRKGRKNSGIWSFCFYIVALCSILLIFTDYFLDDLLFCIIALIPPATLVGCTMLHFQYCALCDIGLEEATSDYTFLLFLVSFLHFAIFLVILRCLESKLGMKTMRMDPVFRISPRTDRVFNNPEEPEGEDEDVRLERERTANALTSVDFQEKPAIIASCLRKEYKGKKKCFVPKSKKKLATRNISFCVRKGEVVGLLGHNGAGKSTSIKIITGEAKPSAGQVLMKGSSRGDTLGFLGYCPQENALWPNLLVREHLEIFAAVKGMSKGDAAVAIARLADALKLQDQMRAPVKTLSEGVKRKLCFALSILGNPSVVLLDEPSTGMDPEGQQQMWQAIQATFTNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKFGKDYLLEMKVRIPAQVEALNAEIKRLFPQAARQERYSSLMVYKLPREDVQPLSQAFFKLETVKQSFDLEEYSLSQSTLEQVFLELSKEQELDCFEDELDPSVQWKLLPQEEA", "length": 1616, "header": "tr|A0A8C2N2S2-1|A0A8C2N2S2_CRIGR Isoform 1 of ATP-binding cassette sub-family A member 8-A OS=Cricetulus griseus OX=10029 GN=LOC100773221 PE=3 SV=1 CANONICAL=A0A8C2N2S2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2S2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2S2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2S2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2S2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773221", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773221", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AM50-1", "protein_name": "ATP binding cassette subfamily A member 9", "gene_name": "ABCA9", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MESPLSAGKMQRVFKKASKINQQTWTLLWKNILLVWRKKTESFQEWITIAILLLLIQISSITIYHYEWQEIPYKFLGRLDDPAFSVRGMKLIYTPATSTTRRIMGRVASGSVLKGIALEEAVNEQNLSARGLFRSDVIGVVFKDDFSYHLRFQSYSVISPIETFEHIDTCYDFSSSFCKVPLYWYEGFLSVQSSIDAAVIEMKTNHSVWEEMKSISGIRLQSPLIKSIRKVGYIWFTIYSMLCFSPYMYFLSVKVIREKKKLKVLMKAMGLQDIAFWLSWSLLYTIYISITSSLLTAITIRSVTHNCSFSEIYFLYFFYGIASIHFCFMLSSLLKQPHITSFVGFFLHVVFGSLGFMMFFEEVPPSLEWVFNLFSPYTFTAGISKIVKLEKYGPTVAAELYPFFNLYGMLILDSILYLLLAIYFDKVLPGKYGVPYPPLFFLRPSYWLQWGSKHSTQPDPIPVPGCDTEPMPEGFEGKEAIRLYNIRKTYKRKGKITEALRGLFFNIYEGQITALLGLSGSGKTALLNVLSGFSKPSAGSAVIYNYKVSEVQDMEGIQAMVGICPQLNLHFEALTVKENLRIFAHVKGIQWKEVEQEVQKVLVQLDLTDLQDVHADSLSGGQKRKLSLAIAILGDPQVLLLDEPMVGLDLCSRHHVWELLAERRAGRVTLICTQSVEEADACADRKAFLSNGRVQCVGSSLYLKRKWGIGYHLRICINDQCDPGLASSLVRRYIPNAVLKGQDGDELCYVLPLENTKSFPDLLGHLDSGLVLGVVHYEVSRTTLADALLQLEGREAIDHKGAENLKESDQSFLGFSEPAHIAASGMELWRQQVLAVARVRFYRLRHDGKLLRSVLLFFGVFIIQMLMVFFGFELWNKSISELTASKYFLPAQPPTQTQSKSTNLLIFNDTGSEIEDFIAALKIQNIMPEITLEKNITSLPRHNGAIKISLEGKHRRYTLMCGAEPINCFPVLINTLSNTFLRLFSSTTRIRIWSHPFSRAEDPELGRGIFFFCLTYMLILAAGLPPQFAVSSVEDYKIKAHAQLRVSGLFPSAYWCGQALVDVPLFWALMCLMFVVVLLFNRICPMQAFIILPLIFSAIGYGFSLIFLVYLIAFIFRKGRTNRYLCSFIFVLVNFTLHMFSFRQGFFYIFSTLMPPYPLLGWLTFSTAHLTFFSNGNLLHDTWSNILVAVFAPYIHSVLFGFLLCCLEIRYGEAVAERDPIFRIQRRRALPPQNNHPPGQEPPEVQAERERARSAVSSLQPKESVIAVNGLRKEYEDKRACSIFKKKKKVAVKNLSFCVKKGEVLGLLGPNGAGKSTTIRMVSGDIAVTAGEVLLQGCRAAVPGCCPQENPLWSDLTVLQHLEAYAAVRGVRGEDAAVFISRVAKALDLQKCLKTPARRLSAGEARKLCFALSILGNPTVMLWDEPTAGMDVAGQRCLWKAIQAAVRSKERAAVLSTHCLEEAAMCDRVAVLVAGQLRYIGSPEELRRKSGMSYHLEVKPKDVGQSDALHSEILHLFPGAARQKRISSLLTYKIPMEDALPLSQAFSKLEAAKQNFRLEEYSLSLHTLQQVFMDFSGDLEEPDLEATNEGAAEQTLLQP", "length": 1599 }, "evidence": [ { "id": "A0A8C2N2S2", "url": "https://omabrowser.org/oma/group/A0A8C2N2S2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZCF8-1", "protein_name": "ATP-binding cassette, subfamily A (ABC1), member 8a", "gene_name": "Abca8a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCDSLVGTKMVKREINVWQQTWALLCKNLLRKKRLKRDTLWELLYTAFILLCLSLFFELHDVYEFSSLSDVDLGRVDSFNDSTFAIAYTPVTPTTQEIMNRVSLVSYMTGREILAFPNKENMTEFISKHYDDAVGIIFSTAYSYHLKFMKGTRIPIIKEHQDHTAHCFRYEPAISCDLSAFWRHGFVALQAAINSAIIEVTTNHSVMEEMMSLTGKYIKIDSFIAQEGTTTDYFLFLCIIAFSPLTYYISAGVTRERKKMKAFMTVMGLRDSAFWLSWGLLYGVIVFIVTLFLTFVVYSVQFVFMTGFMMIFSLFFFYGLSLISLSFLMSVLLKKSFLTDLVVFFLTVSCGSLGFAALYRYLPVSLEWLLSLLSPFAFMLGMTQLLRLDYDLESSGHPTGNPNVVIATVFLLFFDGVFYLMLTFYFEKVLPGEYGRRHPPLFFLKSSFWTGQNPADRTVLDNERDYEFPDDSFEPVSTDFHGKEVIRIRNLTKEYIQRSKRTEALKDLTLDVYKGQITAILGHSGAGKSTLLNVLSGLCVPTKGWVTIHDNKLSEMTDLESISKLTGVCPQCNVQFDFLTVRENLRLFAKIKGIQEVDNEVQRVLLALEMKNIQNTLVQNLSGGQKRKLTFGIAILGDPQIFLLDEPTAGLDPFSRHRVWNLLKERKADRVVLFSTQFMDEADILADRKVFISQGKLRCAGSSLFLKKKWGIGYHLSLQLSETCVHERITSLVKQHIPDSKLSAESEGKLNYILPLERTNKFPDLYRDLERCPDLGIENYGVSVTTLTEVFLKLEGKSAIDSDIGETEDVQAGGTRGPGRLDGEQFVSLLNEMSKTKGGMALWWQQLCAVTRLRFLKLKYRRKSIVILILILGIGLLHILSANVHRLVNQSDYCWELSPHTYFLTPGQRPQMPLTNLLIINKTGEKIDDFLHSLEQQNIALEVDAFGTRNGTEDSQYNGAIIVAGGEKNYNFTLACNTKRLNCFPVLVDIVSNALLGLFTPSVHIQTDRSSFPEDTGYTQFYHLLYMFSWILLMACVPPYISMTSIDDYKNRAQFQLWISGLSPSAYWFGHALFEIPVYSALILSVYIAFYFSAPPESMITTRDLFIQILYAGGYAMSVIFMMYVISFICRKGRKNSGIWSLCFYIVSFISLCLMLFKFFEDTFLFSSIALIPVVTLVGCTLLHFQNHEFPEISLYPERYYTYLFFLAPFFHFLIFLFILRCLERKFGMKTMRMDPVFRISSRSDRVFNNPEEPEGEDEDVSLERVRTANALTSADFQEKPVIIASCLRKEYKGKKKCFVLKGKKKIATRNISLCVRKGEVVGLLGHNGAGKSTSIKMITGEIKPSAGQVQLKGNSTGDTPEFLGYCPQENALWQHMTVREHLEIFAAIKGMSKSDAAVAIARLADALKLQDQLKSPVKTLSEGVKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIQATFANTERGALLTTHYMAEAEAVCDRVAIMVSGKLRCIGSIQHLKSKFGKEYLLEMKVKTPTQVEPLNMEIMRLFPQAARQERYSSLMVYKLPREDVQPLSQAFFKLETVKQSFDLEEYSLSQSTLEQVFLELSKEQELDDFEEELDPSVKWKLLPQEEA", "length": 1624 }, "evidence": [ { "id": "A0A8C2N2S2", "url": "https://omabrowser.org/oma/group/A0A8C2N2S2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K442-1", "protein_name": "ABC-type organic anion transporter ABCA8A", "gene_name": "Abca8a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVKREINVCQQTWALLCKNLLRKKRLKRDTFLEFLYTALILLSLILFLQLHEVYDFSSLPDVDLGRIDSFNDSTFMIVYTPITPTTQRIMDRVSLVSYMTGRKILASPNEENMTELISMRFSDVVGVIFTNAYSYNLKFIKGARIPTIKEHQDHTAHCHSYGEIIYCGLSEFWRDGFVALQAAINAAIIEVTTNHSVMEEMMSLTGKYIKIDSFVGQEGTTTDCFLFFCIIRFSPLTYYISAGVTRERKKMKGLMAVMGLRDSAFWLSWGLLYGVIVFVVTLLSTTIVKLVQFVFLTGFMVIFSLFFFYGLSLISLSFLMSVLLKKSFLTDLVVFLLTVSCGSLGFTALYRYLPVSLEWLLSLLSPFAFMLGMVQLLRLDYDVNSNADPMGNPNEVIGTIFMLFFDGVFYLLLTFYFEKVLPSKSFHDKTYWHACKSHFFLIDYSFYIRTALDNETDYEFSDDSFEPVSMEFHGKEAIRIRNLTKDYIQKSKRTEALKDLTLDVYKGQITAILGHSGAGKSTLLNVLSGLCVPTKGWVTIHNNKLSEMTDLENISKLTGVCPQCNVQFDFLTVRENLRLFAKIKGIQAHEVDNEVQRVLLELDMKNTQNILVQNLSGGQKRKLTFGIAILGDPQIFLLDEPTAGLDPFSRHRVWNFLKERRADRVVLFSTQFMDEADILADRKVFISKGKLKCAGSSLFLKKKWGIGYHLSLQLSETCVHERITSLVKQHIPDSKLSAESEGKLSYILPLERTNKFPDLYRDLERSPDLGIENYGVSITTLTEVFLKLEGKSSIDQSDIGMTEDVQAGGARSPERFAEVEQLVSLLNGRCKMKGGMALWWQQLCAVTRLRFLKLKHERKSIVILILVLGIGLLHILSANIYRMVRQSDYCWELAPHMYFLTPGQQPQPPLTNLLIVNKTGAKIDDFIHSLEQQNIALEVDAFGTRNGTEDSQYNGAIILSGDEKNYNFTLACNTKRLNCFPVLVDIVSNGLLGLFAPSAHIQTDRSTFPEENDHRKFDYLAYFFLWVLLMACVPPYISMTSIDDYKNRAQFQLWISGLSPSAYWFGQALFEVPVYCALILSIFIAFYASAPPESKFTVGDLFIQILYVGGYAMSVIFMTYVISFIYRKGRKNSGLWSLCFYIVSFFSMCFMLIDYFRDISLFVLIALVPPATLGGCTLLHFENREFSEIIFEPEREYSYLFFLAPLLHFAIFVVILRCMERKFGMKTMRTDPVFRISPRSDRVFNNPEDPDGEDEDVSQERVWTANALTSADFQEKPAIIASCLRKEYKGKKKCFVLKSKKKIATRNISFCVRKGEVVGLLGHNGAGKSTSIKMITGETKPSAGQVLLKGSSTGDTPGFLGYCPQENALWLNLTVREHLEIFAAIKGMRKSDANVAIERLADALKLQDQLKSPVKTLSEGVKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIQATFSNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKFGKEYLLEMKVKTPSQVEPLNTEIMRLFPQAARQERYSSLMVYKLPREDVQPLSQAFFKLETVKQSFDLEEYSLSQSTLEQVFLELSKEQELDGFEEELDPSVKWKLLPQEEA", "length": 1620 }, "evidence": [ { "id": "A0A8C2N2S2", "url": "https://omabrowser.org/oma/group/A0A8C2N2S2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WWZ4-1", "protein_name": "ATP-binding cassette sub-family A member 10", "gene_name": "ABCA10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNKMALASFMKGRTVIGTPDEETMDIELPKKYHEMVGVIFSDTFSYRLKFNWGYRIPVIKEHSEYTEHCWAMHGEIFCYLAKYWLKGFVAFQAAINAAIIEVTTNHSVMEELTSVIGINMKIPPFISKGEIMNEWFHFTCLVSFSSFIYFASLNVARERGKFKKLMTVMGLRESAFWLSWGLTYICFIFIMSIFMALVITSIPIVFHTGFMVIFTLYSLYGLSLIALAFLMSVLIRKPMLAGLAGFLFTVFWGCLGFTVLYRQLPLSLGWVLSLLSPFAFTAGMAQITHLDNYLSGVIFPDPSGDSYKMIATFFILAFDTLFYLIFTLYFERVLPDKDGHGDSPLFFLKSSFWSKHQNTHHEIFENEINPEHSSDDSFEPVSPEFHGKEAIRIRNVIKEYNGKTGKVEALQGIFFDIYEGQITAILGHNGAGKSTLLNILSGLSVSTEGSATIYNTQLSEITDMEEIRKNIGFCPQFNFQFDFLTVRENLRVFAKIKGIQPKEVEQEVKRIIMELDMQSIQDIIAKKLSGGQKRKLTLGIAILGDPQVLLLDEPTAGLDPFSRHRVWSLLKEHKVDRLILFSTQFMDEADILADRKVFLSNGKLKCAGSSLFLKRKWGIGYHLSLHRNEMCDTEKITSLIKQHIPDAKLTTESEEKLVYSLPLEKTNKFPDLYSDLDKCSDQGIRNYAVSVTSLNEVFLNLEGKSAIDEPDFDIGKQEKIHVTRNTGDESEMEQVLCSLPETRKAVSSAALWRRQIYAVATLRFLKLRRERRALLCLLLVLGIAFIPIILEKIMYKVTRETHCWEFSPSMYFLSLEQIPKTPLTSLLIVNNTGSNIEDLVHSLKCQDIVLEIDDFRNRNGSDDPSYNGAIIVSGDQKDYRFSVACNTKKLNCFPVLMGIVSNALMGIFNFTELIQMESTSFSRDDIVLDLGFIDGSIFLLLITNCVSPFIGMSSISDYKKNVQSQLWISGLWPSAYWCGQALVDIPLYFLILFSIHLIYYFIFLGFQLSWELMFVLVVCIIGCAVSLIFLTYVLSFIFRKWRKNNGFWSFGFFIILICVSTIMVSTQYEKLNLILCMIFIPSFTLLGYVMLLIQLDFMRNLDSLDNRINEVNKTILLTTLIPYLQSVIFLFVIRCLEMKYGNEIMNKDPVFRISPRSRETHPNPEEPEEEDEDVQAERVQAANALTAPNLEEEPVITASCLHKEYYETKKSCFSTRKKKIAIRNVSFCVKKGEVLGLLGHNGAGKSTSIKMITGCTKPTAGVVVLQGSRASVRQQHDNSLKFLGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAALSISRLVEALKLQEQLKAPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPFTGMDPEGQQQMWQILQATVKNKERGTLLTTHYMSEAEAVCDRMAMMVSGTLRCIGSIQHLKNKFGRDYLLEIKMKEPTQVEALHTEILKLFPQAAWQERYSSLMAYKLPVEDVHPLSRAFFKLEAMKQTFNLEEYSLSQATLEQVFLELCKEQELGNVDDKIDTTVEWKLLPQEDP", "length": 1543 }, "evidence": [ { "id": "A0A8C2N2S2", "url": "https://omabrowser.org/oma/group/A0A8C2N2S2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "sphingomyelin biosynthetic process", "id": "GO:0006686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006686", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2S2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2S2" } ], "pmid": "" }, { "name": "positive regulation of cholesterol efflux", "id": "GO:0010875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010875", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2S2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2S2" } ], "pmid": "" }, { "name": "xenobiotic transmembrane transport", "id": "GO:0006855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006855", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2S2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2S2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2S2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2S2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2S2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2S2" } ], "pmid": "" }, { "name": "ABC-type xenobiotic transporter activity", "id": "GO:0008559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008559", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2S2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2S2" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2S2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2S2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2S2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2S2" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2S2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2S2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2S2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2S2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N4S5-1", "uniprot_ac": "A0A8C2N4S5", "uniprot_id": "A0A8C2N4S5_CRIGR", "mass": { "chemical_mass": 214208.0, "monoisotopic_mass": 214208.0 }, "refseq": { "ac": "XP_035302685", "name": "ral GTPase-activating protein subunit alpha-2 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302685" }, "gene_names": [ { "name": "Ralgapa2", "type": "recommended", "evidence": [ { "id": "A0A8C2N4S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5" } ] }, { "name": "Ralgapa2", "type": "synonym", "evidence": [ { "id": "XP_035302685", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302685" } ] } ], "protein_names": [ { "name": "Ral GTPase-activating protein subunit alpha-2 isoform X5", "type": "synonym", "evidence": [ { "id": "A0A8C2N4S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5/entry#names_and_taxonomy" } ] }, { "name": "ral GTPase-activating protein subunit alpha-2 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_035302685", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302685" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302685", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302685" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4S5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ralgapa2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5", "locus": {} } ], "crossref": [ { "id": "100770884", "url": "https://www.ncbi.nlm.nih.gov/gene/100770884", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770884", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770884", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WLFKAVT", "url": "https://omabrowser.org/oma/group/WLFKAVT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N2U2", "url": "https://www.orthodb.org/?gene=A0A8C2N2U2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N4S5", "url": "https://www.orthodb.org/?gene=A0A8C2N4S5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10063", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10063", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10063:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10063:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302685", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302685", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N2U2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N2U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2U2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N4S5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N4S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H441", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H441", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H441-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H441-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4I6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4I6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4I6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAU4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSRRSHGDVKKSTQKVLDPKKDVLTRLKHLRALLDNVDASDLKQFFETNYSQIYFIFYENFITLENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFFRWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFACLVPGFPAVLSSRGPCTLETLINPSPSVVDAKIYPEEITPLLPAISGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKFLFTLFRKYYLPHLFPSFTKLTNIYKPVLEIPHLRPKPVYVTITRDNETIYSTKIPYMAARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKIIQTVGGGAAQEKVPGLDGDGSTEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRTVYEMVQQILLSTRGYVNFVNEVFRQAFLLPSCEISVTRKVVQVYRKWILQNKPVFMEEPDKKDVAQEDADKLGISETDSKEASSESSGHKRSSSWGRTYSFTSAMSRGCVTEEDNTNVKAGAQAMLQVFLTNAANVFLLEPCAEVPMLLREQVDACKAVLIIFRRMIMELTMNQKTWEQMLQILLRITEAVMQKPKDKHVKDLFAQSLAGLLFRTLIVAWIRANLCVYISRELWDDFLGVLSSLTEWEELITEWSNIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCVLDSQKGTSVGRSFSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNIVRQKATEVEELQQAESTLAADSEYLVVGQQQVPRSSSTSDITEPFCSDSSQGYSPMLPQPAFYMASGDLNSGPYACTAGTLPLSHLPSPGQKVENSQNLSSSESKSVQESKGHVKREHEGITILVRRSSSPAELDLKDDLQQTQGRCRERQKSESTGSDTAVGSSNETELPMSQWQTCDEDPELSTPTDAVPDSDARHWLQLSPTDASNLTDSRECLADDCSIIAGGNLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHARVFGYLYKLWHKLAKIRDNLAVSLDNQSSPSPPLLIPPLRMFASWLFKATTLPNEYKEGKLQAYKLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDVLNTIIRNCSPRFFSLGLPGFSMLVGDFITAAARVLSADMLLVPRSEALTILGSLVCFPNTYRKIPLLQSVPEMSEVITGTEDVKHYLINILLKNATEEPNECARCIAICSLGVWICEELTQCASHPQVKDAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETALPRKMAEILVATIAFLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVNALLHPVSTAVLEELHPPRAPLLDYIYRVLHCCVCGSSTYTQQSHYTLTLADLSSTDYDPFLPLANVRNSEPVQYHSSADLGNLLTVEEEKKRRSVELIPLTARMVMAHLVNHLGHYPLSGGPAVLHSLVSENHDNAHVEGAELSSEVFRSPNLQLFVFNDSTLISYLQTPAEGPDGGTSGGSLSDVRVIVRDISGKYSWDGKVLYGPLEGRLTPSGRNPSFQISGWHQHMCGPQKDLSHSEEGDDALDKLLESIGHTSPECLLPSQLNLNEPSPPPCGMNCDQEKEIIEVILRQSIQEDEYVQRCNSNSAVKVTSQGQPSPVEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILANERGSQAYEDFVAGLGWEVDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGIIPTAFGDVSIIIYPMKNHMFFITITKKPEVPFFGPLFDGAIVSGKLLPSLICATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPSPSYSLSGTD", "length": 1910, "header": "tr|A0A8C2N4S5-1|A0A8C2N4S5_CRIGR Isoform 1 of Ral GTPase-activating protein subunit alpha-2 isoform X5 OS=Cricetulus griseus OX=10029 GN=Ralgapa2 PE=4 SV=1 CANONICAL=A0A8C2N4S5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N2U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5/entry#A0A8C2N2U2-1", "sequence": { "sequence": "MFSRRSHGDVKKSTQKVLDPKKDVLTRLKHLRALLDNVDASDLKQFFETNYSQIYFIFYENFITLENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFFRWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFACLVPGFPAVLSSRGPCTLETLINPSPSVVDAKIYPEEITPLLPAISGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKFLFTLFRKYYLPHLFPSFTKLTNIYKPVLEIPHLRPKPVYVTITRDNETIYSTKIPYMAARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKIIQTVGGGAAQEKVPGLDGDGSTEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRTVYEMVQQILLSTRGYVNFVNEVFRQAFLLPSCEISVTRKVVQVYRKWILQNKPVFMEEPDKKDVAQEDADKLGISETDSKEASSESSGHKRSSSWGRTYSFTSAMSRGCVTEEDNTNVKAGAQAMLQVFLTNAANVFLLEPCAEVPMLLREQVDACKAVLIIFRRMIMELTMNQKTWEQMLQILLRITEAVMQKPKDKHVKDLFAQSLAGLLFRTLIVAWIRANLCVYISRELWDDFLGVLSSLTEWEELITEWSNIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCVLDSQKGTSVGRSFSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNIVRQKATEVEELQQAESTLAADSEYLVVGQQQVPRSSSTSDITEPFCSDSSQGQKVENSQNLSSSESKSVQESKGHVKREHEGITILVRRSSSPAELDLKDDLQQTQGRCRERQKSESTGSDTAVGSSNETELPMSQWQTCDEDPELSTPTDAVPDSDARHWLQLSPTDASNLTDSRECLADDCSIIAGGNLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHARVFGYLYKLWHKLAKIRDNLAVSLDNQSSPSPPLLIPPLRMFASWLFKATTLPNEYKEGKLQAYKLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDVLNTIIRNCSPRFFSLGLPGFSMLVGDFITAAARVLSADMLLVPRSEALTILGSLVCFPNTYRKIPLLQSVPEMSEVITGTEDVKHYLINILLKNATEEPNECARCIAICSLGVWICEELTQCASHPQVKDAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETALPRKMAEILVATIAFLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVNALLHPVSTAVLEELHPPRAPLLDYIYRVLHCCVCGSSTYTQQSHYTLTLADLSSTDYDPFLPLANVRNSEPVQYHSSADLGNLLTVEEEKKRRSVELIPLTARMVMAHLVNHLGHYPLSGGPAVLHSLVSENHDNAHVEGAELSSEVFRSPNLQLFVFNDSTLISYLQTPAEGPDGGTSGGSLSDVRVIVRDISGKYSWDGKVLYGPLEGRLTPSGRNPSFQISGWHQHMCGPQKDLSHSEEGDDALDKLLESIGHTSPECLLPSQLNLNEPSPPPCGMNCDQEKEIIEVILRQSIQEDEYVQRCNSNSAVKVTSQGQPSPVEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILANERGSQAYEDFVAGLGWEVDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGIIPTAFGDVSIIIYPMKNHMFFITITKKPEVPFFGPLFDGAIVSGKLLPSLICATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPSPSYSLSGTD", "length": 1872, "header": "tr|A0A8C2N2U2-1|A0A8C2N4S5_CRIGR Computationally mapped isoform of Ral GTPase-activating protein subunit alpha-2 isoform X5 OS=Cricetulus griseus OX=10029 GN=Ralgapa2 PE=4 SV=1 CANONICAL=A0A8C2N4S5-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N4S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5/entry#A0A8C2N4S5-1", "sequence": { "sequence": "MFSRRSHGDVKKSTQKVLDPKKDVLTRLKHLRALLDNVDASDLKQFFETNYSQIYFIFYENFITLENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFFRWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFACLVPGFPAVLSSRGPCTLETLINPSPSVVDAKIYPEEITPLLPAISGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKFLFTLFRKYYLPHLFPSFTKLTNIYKPVLEIPHLRPKPVYVTITRDNETIYSTKIPYMAARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKIIQTVGGGAAQEKVPGLDGDGSTEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRTVYEMVQQILLSTRGYVNFVNEVFRQAFLLPSCEISVTRKVVQVYRKWILQNKPVFMEEPDKKDVAQEDADKLGISETDSKEASSESSGHKRSSSWGRTYSFTSAMSRGCVTEEDNTNVKAGAQAMLQVFLTNAANVFLLEPCAEVPMLLREQVDACKAVLIIFRRMIMELTMNQKTWEQMLQILLRITEAVMQKPKDKHVKDLFAQSLAGLLFRTLIVAWIRANLCVYISRELWDDFLGVLSSLTEWEELITEWSNIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCVLDSQKGTSVGRSFSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNIVRQKATEVEELQQAESTLAADSEYLVVGQQQVPRSSSTSDITEPFCSDSSQGYSPMLPQPAFYMASGDLNSGPYACTAGTLPLSHLPSPGQKVENSQNLSSSESKSVQESKGHVKREHEGITILVRRSSSPAELDLKDDLQQTQGRCRERQKSESTGSDTAVGSSNETELPMSQWQTCDEDPELSTPTDAVPDSDARHWLQLSPTDASNLTDSRECLADDCSIIAGGNLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHARVFGYLYKLWHKLAKIRDNLAVSLDNQSSPSPPLLIPPLRMFASWLFKATTLPNEYKEGKLQAYKLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDVLNTIIRNCSPRFFSLGLPGFSMLVGDFITAAARVLSADMLLVPRSEALTILGSLVCFPNTYRKIPLLQSVPEMSEVITGTEDVKHYLINILLKNATEEPNECARCIAICSLGVWICEELTQCASHPQVKDAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETALPRKMAEILVATIAFLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVNALLHPVSTAVLEELHPPRAPLLDYIYRVLHCCVCGSSTYTQQSHYTLTLADLSSTDYDPFLPLANVRNSEPVQYHSSADLGNLLTVEEEKKRRSVELIPLTARMVMAHLVNHLGHYPLSGGPAVLHSLVSENHDNAHVEGAELSSEVFRSPNLQLFVFNDSTLISYLQTPAEGPDGGTSGGSLSDVRVIVRDISGKYSWDGKVLYGPLEGRLTPSGRNPSFQISGWHQHMCGPQKDLSHSEEGDDALDKLLESIGHTSPECLLPSQLNLNEPSPPPCGMNCDQEKEIIEVILRQSIQEDEYVQRCNSNSAVKVTSQGQPSPVEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILANERGSQAYEDFVAGLGWEVDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGIIPTAFGDVSIIIYPMKNHMFFITITKKPEVPFFGPLFDGAIVSGKLLPSLICATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPSPSYSLSGTD", "length": 1910, "header": "tr|A0A8C2N4S5-1|A0A8C2N4S5_CRIGR Isoform 1 of Ral GTPase-activating protein subunit alpha-2 isoform X5 OS=Cricetulus griseus OX=10029 GN=Ralgapa2 PE=4 SV=1 CANONICAL=A0A8C2N4S5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H441-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5/entry#A0A9J7H441-1", "sequence": { "sequence": "MFSRRSHGDVKKSTQKVLDPKKDVLTRLKHLRALLDNVDASDLKQFFETNYSQIYFIFYENFITLENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFFRWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFACLVPGFPAVLSSRGPCTLETLINPSPSVVDAKIYPEEITPLLPAISGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKFLFTLFRKYYLPHLFPSFTKLTNIYKPVLEIPHLRPKPVYVTITRDNETIYSTKIPYMAARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKIIQTVGGGAAQEKVPGLDGDGSTEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRTVYEMVQQILLSTRGYVNFVNEVFRQAFLLPSCEISVTRKVVQVYRKWILQNKPVFMEEPDKKDVAQEDADKLGISETDSKEASSESSGHKRSSSWGRTYSFTSAMSRGCVTEEDNTNVKAGAQAMLQVFLTNAANVFLLEPCAEVPMLLREQVDACKAVLIIFRRMIMELTMNQKTWEQMLQILLRITEAVMQKPKDKHVKDLFAQSLAGLLFRTLIVAWIRANLCVYISRELWDDFLGVLSSLTEWEELITEWSNIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCVLDSQKGTSVGRSFSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNIVRQKATEVEELQQAESTLAADSEYLVVGQQQVPRSSSTSDITEPFCSDSSQGQKVENSQNLSSSESKSVQESKGHVKREHEGITILVRRSSSPAELDLKDDLQQTQGRCRERQKSESTGSDTAVGSSNETELPMSQWQTCDEDPELSTPTDAVPDSDARHWLQLSPTDASNLTDSRECLADDCSIIAGGNLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHARVFGYLYKLWHKLAKIRDNLAVSLDNQSSPSPPLLIPPLRMFASWLFKATTLPNEYKEGKLQAYKLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDVLNTIIRNCSPRFFSLGLPGFSMLVGDFITAAARVLSADMLLVPRSEALTILGSLVCFPNTYRKIPLLQSVPEMSEVITGTEDVKHYLINILLKNATEEPNECARCIAICSLGVWICEELTQCASHPQVKDAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETALPRKMAEILVATIAFLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVNALLHPVSTAVLEELHPPRAPLLDYIYRVLHCCVCGSSTYTQQSHYTLTLADLSSTDYDPFLPLANVRNSEPVQYHSSADLGNLLTVEEEKKRRSVELIPLTARMVMAHLVNHLGHYPLSGGPAVLHSLVSENHDNAHVEGAELSSEVFRSPNLQLFVFNDSTLISYLQTPAEGPDGGTSGGSLSDVRVIVRDISGKYSWDGKVLYGPLEGRLTPSGRNPSFQISGWHQHMCGPQKDLSHSEEGDDALDKLLESIGHTSPECLLPSQLNLNEPSPPPCGMNCDQEKEIIEVILRQSIQEDEYVQRCNSNSAVKVTSQGQPSPVEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILANERGSQAYEDFVAGLGWEVDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKVPFFGPLFDGAIVSGKLLPSLICATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPSPSYSLSGTD", "length": 1819, "header": "tr|A0A9J7H441-1|A0A9J7H441_CRIGR Computationally mapped isoform of Ral GTPase-activating protein subunit alpha-2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Ralgapa2 PE=4 SV=1 CANONICAL=A0A8C2N4S5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H4I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5/entry#A0A9J7H4I6-1", "sequence": { "sequence": "MILPCRWELPLKDNAEEMCHVLRQMNCQEADSKAQEDLRGTDFHLNEANFQLMLETKLGVGHLGSRSEKILQFLPERIFFRWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFACLVPGFPAVLSSRGPCTLETLINPSPSVVDAKIYPEEITPLLPAISGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKFLFTLFRKYYLPHLFPSFTKLTNIYKPVLEIPHLRPKPVYVTITRDNETIYSTKIPYMAARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKIIQTVGGGAAQEKVPGLDGDGSTEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRTVYEMVQQILLSTRGYVNFVNEVFRQAFLLPSCEISVTRKVVQVYRKWILQNKPVFMEEPDKKDVAQEDADKLGISETDSKEASSESSGHKRSSSWGRTYSFTSAMSRGCVTEEDNTNVKAGAQAMLQVFLTNAANVFLLEPCAEVPMLLREQVDACKAVLIIFRRMIMELTMNQKTWEQMLQILLRITEAVMQKPKDKHVKDLFAQSLAGLLFRTLIVAWIRANLCVYISRELWDDFLGVLSSLTEWEELITEWSNIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCVLDSQKGTSVGRSFSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNIVRQKATEVEELQQAESTLAADSEYLVVGQQQVPRSSSTSDITEPFCSDSSQGQKVENSQNLSSSESKSVQESKGHVKREHEGITILVRRSSSPAELDLKDDLQQTQGRCRERQKSESTGSDTAVGSSNETELPMSQWQTCDEDPELSTPTDAVPDSDARHWLQLSPTDASNLTDSRECLADDCSIIAGGNLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHARVFGYLYKLWHKLAKIRDNLAVSLDNQSSPSPPLLIPPLRMFASWLFKATTLPNEYKEGKLQAYKLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDVLNTIIRNCSPRFFSLGLPGFSMLVGDFITAAARVLSADMLLVPRSEALTILGSLVCFPNTYRKIPLLQSVPEMSEVITGTEDVKHYLINILLKNATEEPNECARCIAICSLGVWICEELTQCASHPQVKDAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETALPRKMAEILVATIAFLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVNALLHPVSTAVLEELHPPRAPLLDYIYRVLHCCVCGSSTYTQQSHYTLTLADLSSTDYDPFLPLANVRNSEPVQYHSSADLGNLLTVEEEKKRRSVELIPLTARMVMAHLVNHLGHYPLSGGPAVLHSLVSENHDNAHVEGAELSSEVFRSPNLQLFVFNDSTLISYLQTPAEGPDGGTSGGSLSDVRVIVRDISGKYSWDGKVLYGPLEGRLTPSGRNPSFQISGWHQHMCGPQKDLSHSEEGDDALDKLLESIGHTSPECLLPSQLNLNEPSPPPCGMNCDQEKEIIEVILRQSIQEDEYVQRCNSNSAVKVTSQGQPSPVEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILANERGSQAYEDFVAGLGWEVDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGIIPTAFGDVSIIIYPMKNHMFFITITKKPEVPFFGPLFDGAIVSGKLLPSLICATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPSPSYSLSGTD", "length": 1850, "header": "tr|A0A9J7H4I6-1|A0A9J7H4I6_CRIGR Computationally mapped isoform of Ral GTPase-activating protein subunit alpha-2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ralgapa2 PE=4 SV=1 CANONICAL=A0A8C2N4S5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5/entry#A0A9J7KAU4-1", "sequence": { "sequence": "MCHVLRQMNCQEADSKAQEDLRGTDFHLNEANFQLMLETKLGVGHLGSRSEKILQFLPERIFFRWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFACLVPGFPAVLSSRGPCTLETLINPSPSVVDAKIYPEEITPLLPAISGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKFLFTLFRKYYLPHLFPSFTKLTNIYKPVLEIPHLRPKPVYVTITRDNETIYSTKIPYMAARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKIIQTVGGGAAQEKVPGLDGDGSTEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRTVYEMVQQILLSTRGYVNFVNEVFRQAFLLPSCEISVTRKVVQVYRKWILQNKPVFMEEPDKKDVAQEDADKLGISETDSKEASSESSGHKRSSSWGRTYSFTSAMSRGCVTEEDNTNVKAGAQAMLQVFLTNAANVFLLEPCAEVPMLLREQVDACKAVLIIFRRMIMELTMNQKTWEQMLQILLRITEAVMQKPKDKHVKDLFAQSLAGLLFRTLIVAWIRANLCVYISRELWDDFLGVLSSLTEWEELITEWSNIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCVLDSQKGTSVGRSFSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNIVRQKATEVEELQQAESTLAADSEYLVVGQQQVPRSSSTSDITEPFCSDSSQGQKVENSQNLSSSESKSVQESKGHVKREHEGITILVRRSSSPAELDLKDDLQQTQGRCRERQKSESTGSDTAVGSSNETELPMSQWQTCDEDPELSTPTDAVPDSDARHWLQLSPTDASNLTDSRECLADDCSIIAGGNLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHARVFGYLYKLWHKLAKIRDNLAVSLDNQSSPSPPLLIPPLRMFASWLFKATTLPNEYKEGKLQAYKLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDVLNTIIRNCSPRFFSLGLPGFSMLVGDFITAAARVLSADMLLVPRSEALTILGSLVCFPNTYRKIPLLQSVPEMSEVITGTEDVKHYLINILLKNATEEPNECARCIAICSLGVWICEELTQCASHPQVKDAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETALPRKMAEILVATIAFLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVNALLHPVSTAVLEELHPPRAPLLDYIYRVLHCCVCGSSTYTQQSHYTLTLADLSSTDYDPFLPLANVRNSEPVQYHSSADLGNLLTVEEEKKRRSVELIPLTARMVMAHLVNHLGHYPLSGGPAVLHSLVSENHDNAHVEGAELSSEVFRSPNLQLFVFNDSTLISYLQTPAEGPDGGTSGGSLSDVRVIVRDISGKYSWDGKVLYGPLEGRLTPSGRNPSFQISGWHQHMCGPQKDLSHSEEGDDALDKLLESIGHTSPECLLPSQLNLNEPSPPPCGMNCDQEKEIIEVILRQSIQEDEYVQRCNSNSAVKVTSQGQPSPVEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILANERGSQAYEDFVAGLGWEVDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGIIPTAFGDVSIIIYPMKNHMFFITITKKPEVPFFGPLFDGAIVSGKLLPSLICATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPSPSYSLSGTD", "length": 1833, "header": "tr|A0A9J7KAU4-1|A0A8C2N4S5_CRIGR Computationally mapped isoform of Ral GTPase-activating protein subunit alpha-2 isoform X5 OS=Cricetulus griseus OX=10029 GN=Ralgapa2 PE=4 SV=1 CANONICAL=A0A8C2N4S5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2U2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2U2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2U2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2U2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770884", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770884", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BN99-1", "protein_name": "Ral GTPase activating protein catalytic subunit alpha 2", "gene_name": "RALGAPA2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSRRSHGDVKKSTQKVLDPKKDVLTRLKHLRALLDNVDASDLKQFFETNYSQIYFIFYENFITLENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFFRWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFACLVPGFPAIMSSRGPCTLETLLSPSPGVADAKVYPEEITPLVPAMSGEKIAEDQTCFFLQLLLKYMVIQAASLEWKHKENQETGFKFLFTLFRKYYLPHLFPSFTKLTNIYKPVLDVPHLRPKPVYITTTRDNENIYSTKIPYMAARVVFIKWIVTFFLEKKYLSTAQNTKNGVDVLPKIIQTVGGGAAVQDRAPELDSGAAEPDRSHSNSSTLSDRRLSSSSLCSVEEEHRAVYEMVQRILLSTRGYVNFVNEVFRQAFLLPSCDIAVTRKVVQVYRKWILQEKPVFMEEPDIKEVAQEDAEKLGFSETDAKETSSESSGHKRSSSWGRTYSFTSAVSRGCVTEEENQNVKAGAQAMLQVFLTNAANVFLLEPCAEVPMLLKEQVDACKAVLIIFRRMIMELTMNKKTWEQMLQILLRITEAVMQKPKDKQVKDLFAQSLAGLLFRTLMVAWIRANLCVPISRELWDDFLGVLSSRTEWEELINEWASIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCVPDSQKGTTVGRSFSLSWRSHPEMTEPMRFRSATTSGAPGVEKARNIVRQKATEVEECPQQESAPAAEPGAQAADEQQRMVRSSSSPDVTEPLGADAPPGQNVGDTQSVSSSEPRPVQESKGHTKKEHEGITISVRRSSSPAELDLKDDLPQTQGKCRERQKSDSVGSDTGLGYGTDTELSLSPWQTYEEDPDLNTPTDAVTDSDARHWLQLSPTDASHVTDSSECLADDCSIIAGGTLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHARVFGYLYELWYKLAKIRDNLAISLDNQSSPSPPALIPPLRMFASWLFKATTLPNEYKEGKLQAYKLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDILNTIVRHCPPRFFSLGLPGFSMLMGDFITAAARVLSADMLAAPRSEALTILGSLVCFPNTYREVPLLQSLPDVTEVVTGTDDVKHYLISILLKNATEEPNEHARCIAICSLGVWICEELAQCMSHPQLKEAVNVIGVTLKFPNKVVAQVACDVLQLLVSYWEKLQIFEPSLPRKIAEILVATIAFLLPSAEYSSVETDKKLIVSLLLCLLDWCMALPLNALLHPVATAALEEQASSRAPLLDYVYRVLHCCVCGSSTYTQQSHYTLTLADLSSTDYDPFLPLANVKSSEPAQHHSSAELGNLLTVEEERRRRSLELIPLTARMVMAHLVNHLGHFPLCGGPAALHSLVSENHDNAHADAAELSPEVFRSPNLQLFVFNDSTLISCLQTPAQGPADGSPAGALSDVRVIVRDISGKYSWDGKVLYGPLAGCPAPQGRCPSSLVSGWPRPPSGPQKDLSQTDEGEDVLDKLLENIGHTSPECLLPSQLNLNEPSPPPCGMSRDQEKEIIQAILRQSAQEDAYVQRCHSDPALRVASQEQPFPVEPRGAFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKLLRELKHLDSRQCRETHKIAVFYIAEGQEDKCSILSNERGSQAYEDFVAGLGWEVDLSTHCGFMGGLQRNGTTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGIIPTAFGDVSIIIYPMKNHMFFIAITKKPEVPFFGPLFDGAIVSGKLLPSLICATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPSPSYSVTGTD", "length": 1873 }, "evidence": [ { "id": "A0A8C2N4S5", "url": "https://omabrowser.org/oma/group/A0A8C2N4S5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8QI48-1", "protein_name": "Ral GTPase-activating protein subunit alpha-2 isoform X1", "gene_name": "ralgapa2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFTRRVYGDVKKSTQKVLDPKKDVFTRLKHLRALLDIIDRNELKAFFETNCSQIYFIFYENFITLESNLKQKGNKSQREELDSILFIFEKILQLLPEKINSRWQYHSIGSILKKLLHTGNSFKIRCEGMRLFLLWLQALQNHCAEEQLLIFACLIPGFPAVPSSRGPCTLDTIIYNPFSNPPDAKIVPEEITPLVPAVPGEKVADDHTCSVLQIVLKVIVLQASSLDWKNKENQDTGFRFLFSLFKKYYLPHLFPTFSKHTNLYKPQLDLPIHRPKPLYVPVTRNNESTYCTRDQYLAPRVAFITWLVNFFLEKKYVNSTTSNSKNGGEVLPKLIQTVTAGSISQEKSTDLEPNGPVEQEKNHSNSSTLSDRRGSNSSLCSIEEEHRGVYDMVQAILLSTRDNVNFVNEVFHQAFLLPSCEASATRKVIKVYRKWILQEKPAFMAEPETTNQEEDTEEEQLVTETDNAHIQALETHGHKRSSSWGRTYSFSSAISRGCLTEELNLEVKAGIQSALQVFLTNSANVFLLEPCQDVPKLLENQLEVCRAVLSVYRHIIMEQNMNRQTWEQLLQVLLRITEAVMKRPQENQKKDTFAHSLASILFKTIFVAWVRANLTVFISRELWDELLAVLSSLSHWEELVFEWASIMDSLTAVLARHVYGLDLHNLPLDKLSEQKEKKQRGRGVMADSHKVSEAGRSFSLSWKNSGDQVGAQEPMRFRSATTTGTPAVEKARNNVRQKAKRSQSISNCVHLCEALPATKSVPMLLHTVSSFLPGISHNSHCSHRLSDVEECQLSECEMGDGDSPLPRSSSTSDITQQINDTFTGQRKDESMDLVRSSVSESSSAGTRESDAPVILIERSNSPADLDYPAEGAPAFLKMKLREKSESVSSETSNGYLNEAEVGLLSWHTLEEEPDSPSTQDVSMSMSVTADTVSQRSLLLSHTEALAGSPHFPPVSPALLVPHGCCEGPQLLEDAMNMPQHLDSSEFLADDISIIAGGSLTGWHADSAFVLWRRILGILGDVNSIRCARIHAKVFSYLYELWHKLAKIRDNLGIRVDSDTAMVKPLFIPPLRMLASWLFKATMLPSEFKAGKLQAYKLICEMMTKHQDVLPNSDFLVHLYHVMHKGFTSDDQDVLNTMIRWCSPRFFFLGLPGFTMLVGDFITAAARILNTDSFEAPRVEAQAVLGSLVCFPNLYQQIPSLQSVPGSEDILVGKEDMKDYLVNILLKTARSETCEGARCVAICGLGLWVCEELRQTETHHQVKDAINVLGVTLKFGNKVVANVACDIFQLLISHWQHLQRLEPSLPKRIIEIFVATVAFLLPSAEHSTVEADKKLMVSLLLCLLDWCMSVPLSILLEPITMPVLDDPTSQKAPLLDYIYRVLHTCVSGSNLHTQQSHYLLSLADLSTDYEPFLMLGNVKSFEPPAIHNAMGDFGNLLTVAEEKKRRSMELIPLTARMVMTHLVNHLGHHPLSGGPALLNSLISENHDNPYVESSELSSEVFKSPNLQLFVFNDSTLISYLQIPSDNSNTAPLSANPRDHSSEVRIIIRDISGKYSWDSGVLFRTLDGTGVTSSDSREQSSHEAARLEKRSSVRFSKCSSELDVEDGVDVLDQLLEDLGHSSPECLPEPQLRLTQPPSPPMGMNLEIEGLIMEAVHRQSKQEEEELMRRQIEDPSVRAERQKEPTHQEPKSPFYLCRLLLNDLGMNSWDRRKSFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIGEGQEDKYSILSNTQGSQVYEDFVSGLGWEVNLATHCGFMGGLQRNGSTGSTAPYYATSNVEVIFHVSTRMPSDSDDSITKKLRHLGNDEVHIVWSEHTRDYRRGIIPTDFGDVLVIIYPMKNHMFFVQIMKKPQVPFFGPLFDGAIVTGELLPSLVRATCINASRAVKSRLPLYQSFYEERALYLEAIIQNHKENMTFEDFAAQVFSPSPSYWPSGGAGSLSCSTSADLSVSVMTNDSGDQVSPTIPRATKNRVSGKLRRSASAISKSSN", "length": 2015 }, "evidence": [ { "id": "A0A8C2N4S5", "url": "https://omabrowser.org/oma/group/A0A8C2N4S5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A3KGS3-1", "protein_name": "Ral GTPase-activating protein subunit alpha-2", "gene_name": "Ralgapa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRRSHGDVKKSTQKVLDPKKDVLTRLKHLRALLDNVDASDLKQFFETNYSQIYFIFYENFITLENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFFRWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFACLVPGFPAVLSSRGPCTLETLINPSPSIVDAKIYPEEITPLLPAISGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKFLFTLFRKYYLPHLFPSFTKLTNIYKPVLEIPHLRPKPVYVTVTRDNETIYSTKIPYMAARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKIIQTVGGGAIQEKVPELDGAGSTEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRTVYEMVQRILLSTRGYVNFVNEVFRQAFLLPSCEISVTRKVVQVYRKWILQNKPVFMEEPDKKDVAQEDADKLGLSETDSKEASSESSGHKRSSSWGRTYSFTSAMSRGCVTEEDNTNVKAGAQAMLQVFLTNAANVFLLEPCAEVPMLLREQVDASKAVLIIFRRMIMELTMNQKTWEQMLQILLRITEAVMQKPKDKHVKDLFAQSLAGLLFRTLIVAWIRANLCVYISRELWDDFLRVLSSLTEWEELITEWSNIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCILEPQKGTAVGRSFSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNTVRQKATEVEEFQQAESTAAADCDYLVVGQQQVPRSSSTSDITERLYSDSSQGQKVEHSQNLSSSEPKSVQESKGHVTHEHEGITMLVRRSSSPAELELKDDLQQAHGRCRQRQTSESTGSDTVVGYSNEAELPVSPWQACEEDPDLSTPTDAVADSDARHWLQLSPTDASNLTDSRECLADDCSIIAGGNLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHAKVFGYLYELWYKLAKIRDNLAISLDNQSSPSPPLLIPPLRMFASWLFKATTLPNEYKEGKLQAYKLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDVLNTIIKNCSPRFFSLGLPGFSMLVGDFITAAARVLSTDMLAAPRSEALTLLGSLVCFPNTYQEIPLLQSVPEVSDVVTGAEDVKHYLINILLKNATEEPNECARCIAICSLGVWICEELAQSASHPQVKDAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETALPRKMAEILVATIAFLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVSALLHPVSTAVLEELHPSRAPLLDYIYRVLHCCVCGSSTYTQQSHYTLTLADLSSTDYDPFLPLANVRNSEPIQYHSSADLGNLLTVEEEKKRRSVELIPLTARMVMAHLVNHLGHYPLSGGPAVLHSLVSENHDNAHVEGTELSSEVFRSPNLQLFVFNDSTLISYLQTPAEGPAGGTSGGSLSDVRVIVRDISGKYSWDGKVLYGPLEGRLAPNGRNPSFQISGWHHHTCGPQKDLFNGEEGDDVLDKLLENIGHTSPECLLPSQLNLNEPSPTPCAMNWDQEKAIMEVILRQSAQEDEYVQRCNSDSSVTVTSQGQPSPVEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILANERGSQAYEDFVAGLGWEVDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGIIPTAFGDVSIIIYPMKNHMFFITITKKPEVPFFGPLFDGAIVSGKLLPSLICATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPSPSYSVSGTD", "length": 1872 }, "evidence": [ { "id": "A0A8C2N4S5", "url": "https://omabrowser.org/oma/group/A0A8C2N4S5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P86411-1", "protein_name": "Ral GTPase-activating protein subunit alpha-2", "gene_name": "Ralgapa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSRRSHGDVKKSTQKVLDPKKDVLTRLKHLRALLDNVDASDLKQFFETNYSQIYFIFYENFITLENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFFRWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFACLVPGFPAVLSSRGPCTLETLINPSPSVVDAKIYPEEITPLLPAVSGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKFLFTLFRKYYLPHLFPSFTKLTNIYKPVLEIPHLRPKPLYVTVTRDNETIYSTKIPYMAARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKIIQTVGGGAIQEKVPELDGAGATEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRTVYEMVQRILLSTRGYVNFVNEVFRQAFLLPSCEISITRKVVQVYRKWILQNKPVFMEEPDKKDVAEEDADKLGLSETDSKEVSSESSGHKRSSSWGRTYSFTSAMSRGCVTEEDNTNVKAGAQAMLQVFLTNAANVFLLEPCVEVPMLLREQVDACKAVLIIFRRMIMELTMNQKTWEQMLQILLRITEAVMQKPKDKLVQDSFARSLAGLLFRTLIVAWIRANLCVYISRELWDDFLRVLSSLTEWEELITEWSNIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCVLEPQKGTAVGRSFSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNTVRQKATEVEEFQQAESTAAADCDYLVVGQQPVPRSSSTSDITERLYSDSSQGQKVENSQNLSSSEPKSVQESKGHVTHEHEGVTILVRRSSSPAELDLKEESQQTHGRCRERQKSESTGSDMAVGYSNEAELPVSPWQTCEEDPELSTPTDAVADSDARHWLQLSPTDASNLTESRECLADDCSIIAGGNLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHAKVFSYLYELWYKLAKIRDNLAISLDNQSSPSPPLLIPPLRMFASWLFKATTLPNEYKEGKLQAYKLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDVLNTIIKNCSPRFFSLGLPGFSMLVGDFITAAARVLSTDMLAAPRSEALTLLGSLVCFPNTYQEIPLLQSVPEVSDVVTGAEDVKHYLINILLKNATEEPNECARCIAICSLGVWICEELAQCASHPQVKDAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETALPRKMAEILVATIAFLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVSALLHPVSTAVIEELHPSRAPLLDYIYRVLHCCVCGSSTYTQQSHYTLTLADLSSTDYDPFLPLANVRNSEPVQYHSSADLGNLLTVEEEKKRRSVELIPLTARMVMAHLVNHLGHYPLSGGPAVLHSLVSENHDNAHVEGTELSSEVFRSPNLQLFVFNDSTLISYLQTPAEGPAGGTSGGSLSDVRVIVRDISGKYSWDGKVLYGPLEGRLAPSGRNPSFQISGWHHHTCGPQSNLFHGEEGDDVLDKLLENIGHTSPECLLPSQLNLNEPSPTPSAMNCDQEKEIIEVILRQSTQEDEYVQRCHSNSAVKVTSQGQPSPVEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILANERGSQAYEDFVAGLGWEVDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGIIPTAFGDVSIIIYPMKNHMFFITITKKPEVPFFGPLFDGAIVSGKLLPSLICATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPSPSYSLSGTD", "length": 1872 }, "evidence": [ { "id": "A0A8C2N4S5", "url": "https://omabrowser.org/oma/group/A0A8C2N4S5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2PPJ7-1", "protein_name": "Ral GTPase-activating protein subunit alpha-2", "gene_name": "RALGAPA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSRRSHGDVKKSTQKVLDPKKDVLTRLKHLRALLDNVDANDLKQFFETNYSQIYFIFYENFIALENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFFRWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFACLVPGFPAVMSSRGPCTLETLINPSPSVADVKIYPEEITPLLPAISGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKFLFTLFRKYYLPHLFPSFTKLTNIYKPVLDIPHLRPKPVYITTTRDNENIYSTKIPYMAARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKIIQTVGGGAVQERAPELDGGGPTEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRMVYEMVQRILLSTRGYVNFVNEVFHQAFLLPSCEIAVTRKVVQVYRKWILQDKPVFMEEPDRKDVAQEDAEKLGFSETDSKEASSESSGHKRSSSWGRTYSFTSAMSRGCVTEEENTNVKAGVQALLQVFLTNSANIFLLEPCAEVPVLLKEQVDACKAVLIIFRRMIMELTMNKKTWEQMLQILLRITEAVMQKPKDKQIKDLFAQSLAGLLFRTLMVAWIRANLCVYISRELWDDFLGVLSSLTEWEELINEWANIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCVLDPQKGTTVGRSFSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNIVRQKATEVEECQQSENAPAAGSGHLTVGQQQQVLRSSSTSDIPEPLCSDSSQGQKAENTQNSSSSEPQPIQENKGHVKREHEGITILVRRSSSPAELDLKDDLQQTQGKCRERQKSESTNSDTTLGCTNEAELSMGPWQTCEEDPELNTPTDVVADADARHWLQLSPTDASNLTDSSECLTDDCSIIAGGSLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHARVFCYLYELWYKLAKIRDNLAISLDNQSSPSPPVLIPPLRMFASWLFKAATLPNEYKEGKLQAYRLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDILNTIIRHCPPRFFSLGFPGFSMLVGDFITAAARVLSTDILTAPRSEAVTVLGSLVCFPNTYQEIPLLQSVPEVNEAITGTEDVKHYLINILLKNATEEPNEYARCIAVCSLGVWICEELAQCTSHPQVKEAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETSLPRKMAEILVATVAFLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVSVLLHPVSTAVLEEQHSARAPLLDYIYRVLHCCVCGSSTYTQQSHYILTLADLSSTDYDPFLPLANVKSSEPVQYHSSAELGNLLTVEEEKKRRSLELIPLTARMVMAHLVNHLGHYPLSGGPAILHSLVSENHDNAHVEGSELSFEVFRSPNLQLFVFNDSTLISYLQTPTEGPVGGSPVGSLSDVRVIVRDISGKYSWDGKVLYGPLEGCLAPNGRNPSFLISSWHRDTFGPQKDSSQVEEGDDVLDKLLENIGHTSPECLLPSQLNLNEPSLTPCGMNYDQEKEIIEVILRQNAQEDEYIQSHNFDSAMKVTSQGQPSPVEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILSNERGSQAYEDFVAGLGWEVDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGIIPTAFGDVSIIIYPMKNHMFFIAITKKPEVPFFGPLFDGAIVSGKLLPSLVCATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSPSPSYSLSGTD", "length": 1873 }, "evidence": [ { "id": "A0A8C2N4S5", "url": "https://omabrowser.org/oma/group/A0A8C2N4S5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4S5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4S5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4S5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4S5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4S5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1015, "end_pos": 1017, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1098, "end_pos": 1100, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1185, "end_pos": 1187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1469, "end_pos": 1471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1737, "end_pos": 1739, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1854, "end_pos": 1856, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 826, "end_pos": 828, "annotation": "n_glycosylation_sequon" }, { "start_pos": 894, "end_pos": 896, "annotation": "n_glycosylation_sequon" }, { "start_pos": 937, "end_pos": 939, "annotation": "n_glycosylation_sequon" }, { "start_pos": 956, "end_pos": 958, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N4S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4S5" }, { "id": "PS50085", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50085" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rap-GAP", "eco_id": "ECO_0000259", "start_pos": 1672, "end_pos": 1880, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1015, "end_pos": 1017 }, { "start_pos": 1098, "end_pos": 1100 }, { "start_pos": 1185, "end_pos": 1187 }, { "start_pos": 1469, "end_pos": 1471 }, { "start_pos": 1737, "end_pos": 1739 }, { "start_pos": 1854, "end_pos": 1856 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 374, "end_pos": 376 }, { "start_pos": 50, "end_pos": 52 }, { "start_pos": 75, "end_pos": 77 }, { "start_pos": 826, "end_pos": 828 }, { "start_pos": 894, "end_pos": 896 }, { "start_pos": 937, "end_pos": 939 }, { "start_pos": 956, "end_pos": 958 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N2Y4-1", "uniprot_ac": "A0A8C2N2Y4", "uniprot_id": "A0A8C2N2Y4_CRIGR", "mass": { "chemical_mass": 91028.0, "monoisotopic_mass": 91028.0 }, "refseq": { "ac": "XP_027255150", "name": "polyhomeotic-like protein 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255150" }, "gene_names": [ { "name": "Phc2", "type": "recommended", "evidence": [ { "id": "A0A8C2N2Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2Y4" } ] }, { "name": "Phc2", "type": "synonym", "evidence": [ { "id": "XP_027255150", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255150" } ] } ], "protein_names": [ { "name": "Polyhomeotic-like protein 2 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A8C2N2Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2Y4/entry#names_and_taxonomy" } ] }, { "name": "polyhomeotic-like protein 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027255150", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255150" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027255150", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255150" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2Y4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Phc2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2Y4", "locus": {} } ], "crossref": [ { "id": "cd09577", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09577", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756136", "url": "https://www.ncbi.nlm.nih.gov/gene/100756136", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756136", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756136", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N2Y4", "url": "https://www.orthodb.org/?gene=A0A8C2N2Y4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247:SF86", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247:SF86", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16616", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16616", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21319", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21319", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027255150", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255150", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N2Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FCP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FCP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GQ50", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GQ50-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8J0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8J0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8J0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8J0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JDY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JDY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JE33", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JE33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JE33-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JE33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENELPVPHTSSRASVTSNTSGTSSSSGCNSSSNSGGGSGRPTAPQISVYSGIPDRQTVQVIQQALHRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHHLSSAQLQSLAAVQQASLVANRQGSTSGSSVSSQAPTQSPSLNLAAAPATAQLINRAQSVNSATASGLTQQAVLLGNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELSTGSPARPPTPAQVQNLTLRTQQTPPAAASGPTPTQPVLPSLALKPTAGSSQPLPAPPQGRNTAQGPSAGAKPGITDSVTEPLKKGDGGGSLPGNMEGRPGLGRTVPAVATHPLVAPAYAQLQPHQLLPQPSSKHPQPQFVIQQQPQSQQPQPPRPAPQVQSQPQLAPVSPSLALQSSPEDNAMPLGPVTPALPLQCPTAHLHKPGSSQQCHLPTPDTGSQNGHPEGMSHTPQRRFQHTSAVILQLQPASPVSQQCAPDDWKEVVPGEKGVPVTRPGPPLHQQAIITAMPGGLPVPKSPNIQQCPAHETGQGIVHALTDLSTPGMTSGNGNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS", "length": 858, "header": "tr|A0A8C2N2Y4-1|A0A8C2N2Y4_CRIGR Isoform 1 of Polyhomeotic-like protein 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Phc2 PE=4 SV=1 CANONICAL=A0A8C2N2Y4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N2Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2Y4/entry#A0A8C2N2Y4-1", "sequence": { "sequence": "MENELPVPHTSSRASVTSNTSGTSSSSGCNSSSNSGGGSGRPTAPQISVYSGIPDRQTVQVIQQALHRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHHLSSAQLQSLAAVQQASLVANRQGSTSGSSVSSQAPTQSPSLNLAAAPATAQLINRAQSVNSATASGLTQQAVLLGNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELSTGSPARPPTPAQVQNLTLRTQQTPPAAASGPTPTQPVLPSLALKPTAGSSQPLPAPPQGRNTAQGPSAGAKPGITDSVTEPLKKGDGGGSLPGNMEGRPGLGRTVPAVATHPLVAPAYAQLQPHQLLPQPSSKHPQPQFVIQQQPQSQQPQPPRPAPQVQSQPQLAPVSPSLALQSSPEDNAMPLGPVTPALPLQCPTAHLHKPGSSQQCHLPTPDTGSQNGHPEGMSHTPQRRFQHTSAVILQLQPASPVSQQCAPDDWKEVVPGEKGVPVTRPGPPLHQQAIITAMPGGLPVPKSPNIQQCPAHETGQGIVHALTDLSTPGMTSGNGNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS", "length": 858, "header": "tr|A0A8C2N2Y4-1|A0A8C2N2Y4_CRIGR Isoform 1 of Polyhomeotic-like protein 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Phc2 PE=4 SV=1 CANONICAL=A0A8C2N2Y4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FCP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2Y4/entry#A0A9J7FCP6-1", "sequence": { "sequence": "MENELPVPHTSSRASVTSNTSGTSSSSGCNSSSNSGGGSGRPTAPQISVYSGIPDRQTVQVIQQALHRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHHLSSAQLQSLAAVQQASLVANRQGSTSGSSVSSQAPTQSPSLNLAAAPATAQLINRAQSVNSATASGLTQQAVLLGNTSSPALTASQAQMYLRAQMVQNLTLRTQQTPPAAASGPTPTQPVLPSLALKPTAGSSQPLPAPPQGRNTAQGPSAGAKPGITDSVTEPLKKGDGGGSLPGNMEGRPGLGRTVPAVATHPLVAPAYAQLQPHQLLPQPSSKHPQPQFVIQQQPQSQQPQPPRPAPQVQSQPQLAPVSPSLALQSSPEDNAMPLGPVTPALPLQCPTAHLHKPGSSQQCHLPTPDTGSQNGHPEGMSHTPQRRFQHTSAVILQLQPASPVSQQCAPDDWKEVVPGEKGVPVTRPGPPLHQQAIITAMPGGLPVPKSPNIQQCPAHETGQGIVHALTDLSTPGMTSGNGNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS", "length": 829, "header": "tr|A0A9J7FCP6-1|A0A8C2N2Y4_CRIGR Computationally mapped isoform of Polyhomeotic-like protein 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Phc2 PE=4 SV=1 CANONICAL=A0A8C2N2Y4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GQ50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2Y4/entry#A0A9J7GQ50-1", "sequence": { "sequence": "MENELPVPHTSSRASVTSNTSGTSSSSGCNSSSNSGGGSGRPTAPQISVYSGIPDRQTVQVIQQALHRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHHLSSAQLQSLAAVQQLNLAAAPATAQLINRAQSVNSATASGLTQQAVLLGNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELSTGSPARPPTPAQVQNLTLRTQQTPPAAASGPTPTQPVLPSLALKPTAGSSQPLPAPPQGRNTAQGPSAGAKPGITDSVTEPLKKGDGGGSLPGNMEGRPGLGRTVPAVATHPLVAPAYAQLQPHQLLPQPSSKHPQPQFVIQQQPQSQQPQPPRPAPQVQSQPQLAPVSPSLALQSSPEDNAMPLGPVTPALPLQCPTAHLHKPGSSQQCHLPTPDTGSQNGHPEGMSHTPQRRFQHTSAVILQLQPASPVSQQCAPDDWKEVVPGEKGVPVTRPGPPLHQQAIITAMPGGLPVPKSPNIQQCPAHETGQGIVHALTDLSTPGMTSGNGNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS", "length": 832, "header": "tr|A0A9J7GQ50-1|A0A9J7GQ50_CRIGR Computationally mapped isoform of Polyhomeotic-like protein 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Phc2 PE=4 SV=1 CANONICAL=A0A8C2N2Y4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J8J0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2Y4/entry#A0A9J7J8J0-1", "sequence": { "sequence": "MLPETMKTFPGTDRILWEVIQQALHRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHHLSSAQLQSLAAVQQASLVANRQGSTSGSSVSSQAPTQSPSLNLAAAPATAQLINRAQSVNSATASGLTQQAVLLGNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELSTGSPARPPTPAQVQNLTLRTQQTPPAAASGPTPTQPVLPSLALKPTAGSSQPLPAPPQGRNTAQGPSAGAKPGITDSVTEPLKKGDGGGSLPGNMEGRPGLGRTVPAVATHPLVAPAYAQLQPHQLLPQPSSKHPQPQFVIQQQPQSQQPQPPRPAPQVQSQPQLAPVSPSLALQSSPEDNAMPLGPVTPALPLQCPTAHLHKPGSSQQCHLPTPDTGSQNGHPEGMSHTPQRRFQHTSAVILQLQPASPVSQQCAPDDWKEVVPGEKGVPVTRPGPPLHQQAIITAMPGGLPVPKSPNIQQCPAHETGQGIVHALTDLSTPGMTSGNGNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS", "length": 816, "header": "tr|A0A9J7J8J0-1|A0A9J7J8J0_CRIGR Computationally mapped isoform of Polyhomeotic-like protein 2 isoform X6 OS=Cricetulus griseus OX=10029 GN=Phc2 PE=4 SV=1 CANONICAL=A0A8C2N2Y4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JDY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2Y4/entry#A0A9J7JDY0-1", "sequence": { "sequence": "MTSGNGNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS", "length": 323, "header": "tr|A0A9J7JDY0-1|A0A9J7JDY0_CRIGR Computationally mapped isoform of Polyhomeotic-like protein 2 isoform X8 OS=Cricetulus griseus OX=10029 GN=Phc2 PE=4 SV=1 CANONICAL=A0A8C2N2Y4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JE33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2Y4/entry#A0A9J7JE33-1", "sequence": { "sequence": "MGKGKLFCGSSSIFRRAFSHPPVPNEETGQGIVHALTDLSTPGMTSGNGNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS", "length": 366, "header": "tr|A0A9J7JE33-1|A0A9J7JE33_CRIGR Computationally mapped isoform of Polyhomeotic-like protein 2 isoform X7 OS=Cricetulus griseus OX=10029 GN=Phc2 PE=4 SV=1 CANONICAL=A0A8C2N2Y4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 221, "start_aa": "Thr", "end_pos": 221, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr221", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 244, "start_aa": "Thr", "end_pos": 244, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr244", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 246, "start_aa": "Thr", "end_pos": 246, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr246", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 401, "start_aa": "Thr", "end_pos": 401, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr401", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FCP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCP6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FCP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCP6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756136", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756136", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2Y4" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N2Y4", "url": 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Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035300822", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300822" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N310", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rps6kl1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310", "locus": {} } ], "crossref": [ { "id": "cd02677", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02677", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05576", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05576", "database": "CDD", 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"categories": [ "Protein Classification", "Other" ] }, { "id": "PF04212", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04212", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035300822", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300822", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N310", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N310-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5S0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLVACECPPGPGLELEPCSRARSQACMYLGQIRNRVATGTSDMAKRDYLVDAATQIRLALERDVSEDYEAAFNHYQNGVDVLLRGVHVDPNKERCEAVKLKITKYLRRAEEIFNCHLQRTLGSGAGPSTGFSSLRLRPIRTLSSALEQLRGCRVVGIIEKVQLVQDPATGGTFIVKSLPRCHMVSQERLTVIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLSQARFQYSGLKSGSAQDKSKFRLNTSFCLMTPAKLSPGHTLGQDRVPVEPPWTSQSLPPAKEMPPHQLQEEADSEPSARTSPFCSSNLTEAPCGRLRSQVRRAGQNSNLAPNRKLHWVREGADRVLGAYGRGRGQNPPSANRASLGCGRAVWSLREEQVKQWAAELLVALEALHEQGVLCRDLNPRNLLLDQAGHIRLTYFGQWSEVEPRCSQEAVDCLYCAPEVGGISEVTEACDWWSYGSLLYELLTGMALSQSHPSGFQAHTQLQLPEWLSGPAASLLTELLQFDPQRRLGAGGGGTSKLKSHPFFSTIQWSRLTG", "length": 549, "header": "tr|A0A8C2N310-1|A0A8C2N310_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Rps6kl1 PE=4 SV=1 CANONICAL=A0A8C2N310-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N310-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310/entry#A0A8C2N310-1", "sequence": { "sequence": "MSLVACECPPGPGLELEPCSRARSQACMYLGQIRNRVATGTSDMAKRDYLVDAATQIRLALERDVSEDYEAAFNHYQNGVDVLLRGVHVDPNKERCEAVKLKITKYLRRAEEIFNCHLQRTLGSGAGPSTGFSSLRLRPIRTLSSALEQLRGCRVVGIIEKVQLVQDPATGGTFIVKSLPRCHMVSQERLTVIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLSQARFQYSGLKSGSAQDKSKFRLNTSFCLMTPAKLSPGHTLGQDRVPVEPPWTSQSLPPAKEMPPHQLQEEADSEPSARTSPFCSSNLTEAPCGRLRSQVRRAGQNSNLAPNRKLHWVREGADRVLGAYGRGRGQNPPSANRASLGCGRAVWSLREEQVKQWAAELLVALEALHEQGVLCRDLNPRNLLLDQAGHIRLTYFGQWSEVEPRCSQEAVDCLYCAPEVGGISEVTEACDWWSYGSLLYELLTGMALSQSHPSGFQAHTQLQLPEWLSGPAASLLTELLQFDPQRRLGAGGGGTSKLKSHPFFSTIQWSRLTG", "length": 549, "header": "tr|A0A8C2N310-1|A0A8C2N310_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Rps6kl1 PE=4 SV=1 CANONICAL=A0A8C2N310-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310/entry#A0A9J7GZJ9-1", "sequence": { "sequence": "MSLVACECPPGPGLELEPCSRARSQACMYLGQIRNRVATGTSDMAKRDYLVDAATQIRLALERDVSEDYEAAFNHYQNVDPNKERCEAVKLKITKYLRRAEEIFNCHLQRTLGSGAGPSTGFSSLRLRPIRTLSSALEQLRGCRVVGIIEKVQLVQDPATGGTFIVKSLPRCHMVSQERLTVIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLSQARFQYSGLKSGSAQDKSKFRLNTSFCLMTPAKLSPGHTLGQDRVPVEPPWTSQSLPPAKEMPPHQLQEEADSEPSARTSPFCSSNLTEAPCGRLRSQVRRAGQNSNLAPNRKLHWVREGADRVLGAYGRGRGQNPPSANRASLGCGRAVWSLREEQVKQWAAELLVALEALHEQGVLCRDLNPRNLLLDQAGHIRLTYFGQWSEVEPRCSQEAVDCLYCAPEVGGISEVTEACDWWSYGSLLYELLTGMALSQSHPSGFQAHTQLQLPEWLSGPAASLLTELLQFDPQRRLGAGGGGTSKLKSHPFFSTIQWSRLTG", "length": 539, "header": "tr|A0A9J7GZJ9-1|A0A9J7GZJ9_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Rps6kl1 PE=4 SV=1 CANONICAL=A0A8C2N310-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JYE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310/entry#A0A9J7JYE1-1", "sequence": { "sequence": "MSLVACECPPGPGLELEPCSRARSQACMYLGQIRNRVATGTSDMAKRDYLVDAATQIRLALERDVSEDYEAAFNHYQNGVDVLLRGVHVDPNKERCEAVKLKITKYLRRAEEIFNCHLQRTLGSGAGPSTGFSSLRLRPIRTLSSALEQLRGCRVVGIIEKVQLVQDPATGGTFIVKSLPRCHMVSQERLTVIPHGVPYMTKLLRYFVSEDSIFLHLEHVQEVGGISEVTEACDWWSYGSLLYELLTGMALSQSHPSGFQAHTQLQLPEWLSGPAASLLTELLQFDPQRRLGAGGGGTSKLKSHPFFSTIQWSRLTG", "length": 317, "header": "tr|A0A9J7JYE1-1|A0A8C2N310_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Rps6kl1 PE=4 SV=1 CANONICAL=A0A8C2N310-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K5S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310/entry#A0A9J7K5S0-1", "sequence": { "sequence": "MSLVACECPPGPGLELEPCSRARSQACMYLGQIRNRVATGTSDMAKRDYLVDAATQIRLALERDVSEDYEAAFNHYQNGVDVLLRGVHVDPNKERCEAVKLKITKYLRRAEEIFNCHLQRTLGSGAGPSTGFSSLRLRPIRTLSSALEQLRGCRVVGIIEKSLPRCHMVSQERLTVIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLSQARFQYSGLKSGSAQDKSKFRLNTSFCLMTPAKLSPGHTLGQDRVPVEPPWTSQSLPPAKEMPPHQLQEEADSEPSARTSPFCSSNLTEAPCGRLRSQVRRAGQNSNLAPNRKLHWVREGADRVLGAYGRGRGQNPPSANRASLGCGRAVWSLREEQVKQWAAELLVALEALHEQGVLCRDLNPRNLLLDQAGHIRLTYFGQWSEVEPRCSQEAVDCLYCAPEVGGISEVTEACDWWSYGSLLYELLTGMALSQSHPSGFQAHTQLQLPEWLSGPAASLLTELLQFDPQRRLGAGGGGTSKLKSHPFFSTIQWSRLTG", "length": 533, "header": "tr|A0A9J7K5S0-1|A0A8C2N310_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Rps6kl1 PE=4 SV=1 CANONICAL=A0A8C2N310-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K5S0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K5S0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758757", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758757", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1N860-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "RPS6KL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLVACECPPGPGPEPEPCSRARSQARVYLEQIRNRVAPGAPDMTKHDYLVDAASQIRLALERDVSEDYEAAFNHYQNGVDVLLRGMHVDPNKERCEAVKLKITKYLRRAEEIFNCHLQRTLGSGASPDEGFSSLRLRPIRTLSSALEQLRGCKVVGVIEKVQLVQDLATGGTFVVKGLSRCHMTSRERLTIIPHGVPYMTQLLRYFVTEDSIFLHLEHVKGGTLWSHLLSQPCPQQSGTGSGSSLERMKAPLNSHLSLGTSSVPLGYTRLQDGIPLEPPWTSQSLTPARGVASVKAQREAGGEASARTSTARFWDLPKAPGGCLHSHAGRGPSQSSEPAPPWGLPWVRAGAGRVLGGCCRGTGPSRPSASGGASPVSGGGAWSLKEEQVRQWAAETLLALEALHQQGVLCRDLNPRNLLLDQAGHIRLTYFGQWSEVEPQCCREASHNLYSAPEVGGISELTDACDWWSFGSLLYELLTGTALSQSHPSGIQPHTQLQLPEWLSGPAASLLTELLQFDPARRLGAGGGGVHELKAHPFFSSIQWSKLGG", "length": 550 }, "evidence": [ { "id": "A0A8C2N310", "url": "https://omabrowser.org/oma/group/A0A8C2N310/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8I6AKT7-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Rps6kl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLVACECPPGPGLEPEPCSRARSQACMYLEQIRHWVAAGTADMTKRDYLVDAATQIHLALERDVSEDYEAAFNYYQNGVDVLLRGVHVDPNKERCEAVKLKITKYLRRAEEIFNCHLQRTLGSGTSPNTGFSSLRLRPIRTLSSALEQLKGCRVVGIIKKSLPRCHMVSRERLTIIPHGVPFMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLSQDHFQHSGLKSGSAQEKCKVQLSTGHNLTTPAKLPPGHTLRQDRTPVEPPWTSQSLPPALQLQKEADGEPAPRTSIVYSSDLTEAPCGHLHSQVRRAGQSSNPAPSQRLHWVREGADRVLGAYGRGRAQNPPSANRASLGSGRAAWSLWEGQVKQWAAEMLLALEALHEQGVLCRDLNPQNLLLDQAGHIQLTYFGQWSEVEPQCSQEAVDCLYSAPEVGGISELTEACDWWSYGSLLYELLTGMALSQSHPSGFQAHTQLQLPEWLSRPAASLLTELLQFDPQRRLGAGGGGTSKLKSHPFFSSIQWSRLTG", "length": 528 }, "evidence": [ { "id": "A0A8C2N310", "url": "https://omabrowser.org/oma/group/A0A8C2N310/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S2R9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "RPS6KL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVACECPPGPGPEPEPCSRARSQARLYLEQIRSRVAPGAPDVTKPDYLVDAATQIRLALERDVSEDYEAAFNHYQNGVDVLLRGVHVDPNKERREAVKLKITKYLRRAEEIFNCHLQRTLGSGASSGTGFSSLRLRPIRTLSSALEQLRGCRVVAVIEKVQLVQDPATGGTFVVKSLSRCHVASRERLTIIPHGVPYMTKLLRYFVSEDSIFLQLEHVQGGTLWSHLLSQPHTHQPGTGSGSSLEKKKAQLNARLNPGTPVLFPPGHTHLQDGIPLEPPRTSQSLTPAREPASIRPQREAEGRPSARSSTSCSLDLPKALRGRLHPQARQGPGQGSDSWALPWVRAGAGRVLGGCGQGRGQSRPSADGASPVSGRGAWSVQEEQVRQWAAEMLVALEALHEQGVLCRDLNPQNLLLDQAGHVRLTYFGQWSEVEPQCCREALDNLYGAPEVGGISELTEACDWWSFGSLLYELLTGTALSQSHPSGIQPHTRLQLPEWLSRPAASLLTELLQFEPTLRLGTGTGGVDKLKSHPFFSSIQWSKLVG", "length": 547 }, "evidence": [ { "id": "A0A8C2N310", "url": "https://omabrowser.org/oma/group/A0A8C2N310/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8R2S1-1", "protein_name": "Ribosomal protein S6 kinase-like 1", "gene_name": "Rps6kl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLVACECPPGPGLEPEPCSRARSQACMYLEQIRNRVATGTADVTKRDYLVDAATQIHLALERDVSEDYEAAFNHYQNGVDVLLRGVHVDPNKERREAVKLKITKYLRRAEEIFNCHLQRTLGSGASPNTGFSSLRLRPIRTLSSALEQLKGCRVVGIIKKVQVVQDPATGGTFIVKSLPRCHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLSQDHFQYSGLNSGSVQEKSQAQLSTRLSLMTPAELTPGHTLRQNRIPMEPPRTSQSLPPALQLQKEADAEPSSRPSAVFSSDPTEAPCGHSHSQVRRAGQSSNPAPTQRLHWVREGADRVLGAYGRGRGRNPPSANRASLGSGRAAWSLREGQVKQWAAEMLLALEALHQQGVLCRDLNPQNLLLDQAGHIQLTYFGQWSEVEPRCSQEAVDCLYSAPEVGGISELTEACDWWSYGSLLYELLTGMALSQSHPSGFQAHTQLQLPEWLSHPAASLLTELLQFEPQRRLGAGGGGTSRLKSHPFFSTIQWSRLMG", "length": 544 }, "evidence": [ { "id": "A0A8C2N310", "url": "https://omabrowser.org/oma/group/A0A8C2N310/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VEA9-1", "protein_name": "Ribosomal protein S6 kinase delta-1", "gene_name": "Dmel\\CG7156", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTLNLGGWIHSFTVTDTQEHKGGYTIYKITSIVFPRSVPQALTCLVVWKRFHDVKRLHRELSRRHKSLQLPGKLPVPTDSTYFKRFDAAVIQRRKEYILQLLDFAAQHPALYKCSTFTQFFQETPSPNGSPLKKLYVERSLRLQTEDNGCGSGGSETGTCAGAIADICDKLDLPYDPHDAGGITPLDPRCDKEQTNNESQAKETEIELETKQEPKTDVALTKRDYLRLLTPMASIESDDSDYIYEAALEFSHAVQAEVNLEYAEAHERYKHGVDLLLNGAKQDSSEERRFIAKAKIAKYLARAEEIHANFLANDCPTKKLQFQLSLDTTDGGSVSHLECPWNQLARYKVLQILQDRVMQVQCVTKSQQPAAIMKGVEKPASHSLTQSIFLPQQVPYMVQLLAYFQSEQKIFLLLRQAEGGMLYDYLQSYTPTSSKSVNYGELFPSDQEPEEKEAEEPPLTSDSDVSDLVRSSQQLLKSVTNTLSNLQAGVVTPKRNKKVDQNRIRSKPIPEQCLRQWACELAIAIHSLHGKGVILRDLHMGNILLGAKGQLLLTYFYQNEGLTSDDNYVHKALNLEAVANHFVAPERPLTFRSDWWSYGVVLYQLLLGVPYKVTHPGQLDLYGCVQYPSESLEISDHAKDLLEQLLQLSPELRLDYDQLQAHPFFKGIDWQAVLEQGTESM", "length": 681 }, "evidence": [ { "id": "A0A8C2N310", "url": "https://omabrowser.org/oma/group/A0A8C2N310/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y6S9-1", "protein_name": "Ribosomal protein S6 kinase-like 1", "gene_name": "RPS6KL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLVACECLPSPGLEPEPCSRARSQAHVYLEQIRNRVALGVPDMTKRDYLVDAATQIRLALERDVSEDYEAAFNHYQNGVDVLLRGIHVDPNKERREAVKLKITKYLRRAEEIFNCHLQRPLSSGASPSAGFSSLRLRPIRTLSSAVEQLRGCRVVGVIEKVQLVQDPATGGTFVVKSLPRCHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLSQAHSRHSGLSSGSTQERMKAQLNPHLNLLTPARLPSGHAPGQDRIALEPPRTSPNLLLAGEAPSTRPQREAEGEPTARTSTSGSSDLPKAPGGHLHLQARRAGQNSDAGPPRGLTWVPEGAGPVLGGCGRGMDQSCLSADGAGRGCGRATWSVREEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQCCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQLPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLVG", "length": 549 }, "evidence": [ { "id": "A0A8C2N310", "url": "https://omabrowser.org/oma/group/A0A8C2N310/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N310", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N310", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N310", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", "A0A8C2QND0-1", "G3HXQ8-1", "G3I724-1", "A0A8C2M0A2-1", "A0A9J7K2S5-1", "A0A8C2MMZ5-1", "A0A8C2QH69-1", "A0A8C2QL63-1", "A0A9J7K953-1", "A0A9J7G3C1-1", "A0A9J7GFS3-1", "A0A9J7JBH0-1", "A0A9J7FGD3-1", 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"database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3HX91-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", "A0A8C2QND0-1", "G3HXQ8-1", 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"A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7H540-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H949-1", "A0A9J7GQY0-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] } ] }, { "uniprot_ac": "A0A8C2M497", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] } ] }, { "uniprot_ac": "A0A8C2N185", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] } ] }, { "uniprot_ac": "A0A8C2N210", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] }, { "ec_number": "2.7.11.1", "activity": "", 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"url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] } ] }, { "uniprot_ac": "A0A8C2N457", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] } ] }, { "uniprot_ac": "A0A8C2N4W2", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] } ] 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"id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F821", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] } ] }, { "uniprot_ac": "A0A9J7F8T0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] } ] }, { "uniprot_ac": "A0A9J7G5N9", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": 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"https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] } ] }, { "uniprot_ac": "A0A9J7G9D1", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] } ] }, { "uniprot_ac": "A0A9J7GAB0", "gene_name": "Pkn3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] } ] }, { "uniprot_ac": "A0A9J7GAF4", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] } ] }, { "uniprot_ac": "A0A9J7GD76", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] } ] }, { "uniprot_ac": "A0A9J7GES8", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] } ] }, { "uniprot_ac": "A0A9J7GF59", "gene_name": "LOC103160391", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A9J7GLT3", "gene_name": "LOC113838166", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] } ] }, { "uniprot_ac": "A0A9J7GMF3", "gene_name": "LOC103158537", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] } ] }, { "uniprot_ac": "A0A9J7GMK5", "gene_name": "Sbk3", 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] } ] }, { "uniprot_ac": "A0A9J7H3M5", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] } ] }, { "uniprot_ac": "A0A9J7H3N1", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H4T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4T9" } ] } ] }, { "uniprot_ac": "A0A9J7H503", "gene_name": "LOC100752185", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H503", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H503" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H503", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H503" } ] } ] }, { "uniprot_ac": "A0A9J7H540", "gene_name": "LOC113837157", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ] } ] }, { "uniprot_ac": "A0A9J7J1N3", "gene_name": "Limk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J1N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J1N3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7J1N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J1N3" } ] } ] }, { "uniprot_ac": "A0A9J7J5Z8", "gene_name": "Camk2g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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{ "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP 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"ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JQZ1", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] } ] }, { "uniprot_ac": "A0A9J7JRI3", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] } ] }, { "uniprot_ac": "G3IN30", "gene_name": "Plk1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] } ] }, { "uniprot_ac": "O55076", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] } ] }, { "uniprot_ac": "P25321", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P25321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25321" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P25321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25321" } ] } ] }, { "uniprot_ac": "P50310", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "P50310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50310" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P50310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50310" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "P50310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P50310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50310" } ] } ] }, { "uniprot_ac": "P68180", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68180" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P68180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68180" } ] } ] }, { "uniprot_ac": "Q63980", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q63980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q63980" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q63980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q63980" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 145, "end_pos": 539, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 254, "end_pos": 256 }, { "start_pos": 317, "end_pos": 319 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"A0A8C2N339_CRIGR", "mass": { "chemical_mass": 23905.0, "monoisotopic_mass": 23905.0 }, "refseq": { "ac": "XP_007638417", "name": "meiotic nuclear division protein 1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638417" }, "gene_names": [ { "name": "Mnd1", "type": "recommended", "evidence": [ { "id": "A0A8C2N339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N339" } ] }, { "name": "Mnd1", "type": "synonym", "evidence": [ { "id": "XP_007638417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638417" } ] } ], "protein_names": [ { "name": "Meiotic nuclear division protein 1 homolog", "type": "recommended", "evidence": [ { "id": "A0A8C2N339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N339/entry#names_and_taxonomy" } ] }, { "name": "meiotic nuclear division protein 1 homolog", "type": "synonym", "evidence": [ { "id": "XP_007638417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638417" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613739.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007638417", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638417" } ] }, { "annotation": "Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N339", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N339#function" }, { "database": "UniProtKB", "id": "PIRNR026991", "url": "https://www.uniprot.org/uniprotkb/PIRNR026991#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N339", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N339" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mnd1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N339", "locus": {} } ], "crossref": [ { "id": "100772049", "url": "https://www.ncbi.nlm.nih.gov/gene/100772049", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772049", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772049", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VCYWAFP", "url": "https://omabrowser.org/oma/group/VCYWAFP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N339", "url": "https://www.orthodb.org/?gene=A0A8C2N339", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31398", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31398", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31398:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31398:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03962", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03962", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007638417", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638417", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N339", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N339", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N339-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N339-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKKKGLSAEEKRTRMMEIFFETKDVFQLKDLEKLAPKEKGITAMSVKEVLQSLVDDGMVDCERIGTSNYYWAFPSKALHARKRKLEALTSQLSEGNQRHANLQKSIEKARIGRQETEERAMLTKELSSFRDQREQLKAEVEKYRECDPQVVEEIRKANIVAKEAANRWTDNIFAIKSWAKRKFGFEESKIDKNFGIPEDFDYID", "length": 205, "header": "tr|A0A8C2N339-1|A0A8C2N339_CRIGR Isoform 1 of Meiotic nuclear division protein 1 homolog OS=Cricetulus griseus OX=10029 GN=Mnd1 PE=3 SV=1 CANONICAL=A0A8C2N339-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N339-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N339/entry#A0A8C2N339-1", "sequence": { "sequence": "MSKKKGLSAEEKRTRMMEIFFETKDVFQLKDLEKLAPKEKGITAMSVKEVLQSLVDDGMVDCERIGTSNYYWAFPSKALHARKRKLEALTSQLSEGNQRHANLQKSIEKARIGRQETEERAMLTKELSSFRDQREQLKAEVEKYRECDPQVVEEIRKANIVAKEAANRWTDNIFAIKSWAKRKFGFEESKIDKNFGIPEDFDYID", "length": 205, "header": "tr|A0A8C2N339-1|A0A8C2N339_CRIGR Isoform 1 of Meiotic nuclear division protein 1 homolog OS=Cricetulus griseus OX=10029 GN=Mnd1 PE=3 SV=1 CANONICAL=A0A8C2N339-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N339", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N339" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N339", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N339" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772049", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772049", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LWN6-1", "protein_name": "Meiotic nuclear division protein 1 homolog", "gene_name": "Mnd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKKRGLSGEEKRTRMMEIFFETKDVFQLKDLEKLAPKEKGITAMSVKEVLQSLVDDGMVDCERIGTSNYYWAFPSKALHARKRKLEALNSQLSEGSQKHADLQKSIEKARVGRQETEERAMLAKELSSFQDQRKKLKAEVEKYRECDPQVVEEIRQANKVAKEAANRWTDNIFAIKSWAKRKYGFEETKIDKNFGIPEDFDYVD", "length": 205 }, "evidence": [ { "id": "A0A8C2N339", "url": "https://omabrowser.org/oma/group/A0A8C2N339/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MGT0-1", "protein_name": "Meiotic nuclear division protein 1 homolog", "gene_name": "MND1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSKKKGLSAEEKRTRMMEIFYETKDVFQLKDMEKIAPKEKGITAMSVKEVLQSLVDDGMVDCERIGTSNYYWAFPSKALHARKRKLEVLDSQLSEGNQKYANLQKSIEKAKVGRHETEERTMLAKELSSLRDQREQLKAEVEKYRECDPQVVEEIRQANQVAKEAANRWTDNIFAIKSWAKRKFGFEENKIDKNFGIPEDFDYID", "length": 205 }, "evidence": [ { "id": "A0A8C2N339", "url": "https://omabrowser.org/oma/group/A0A8C2N339/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P53102-1", "protein_name": "Meiotic nuclear division protein 1", "gene_name": "MND1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGPKRQTVSLQEKKNRILNFFQETYTFYNIKELEKSIPKKCGISPMIVKDLVQQMIDEDGVISVEKCGNINIYWCFKNQTLQKLYDSSELIKKKIQEVKCDIATYKQELDKTLATGRRKKFTVGQKSYNREALLEKRKKIQDEIKKKSNSLQKIESIRWDAAKIQENKQQIRLKKVHLEKTTDNIEILIDYLYKKFFLKPEQIRKEFGIPEEFKEFTEV", "length": 219 }, "evidence": [ { "id": "A0A8C2N339", "url": "https://omabrowser.org/oma/group/A0A8C2N339/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54E86-1", "protein_name": "Meiotic nuclear division protein 1 homolog", "gene_name": "mnd1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRRKGMSPEEKKEKLKEFFHSNSTIYSSKDVESEASKYTGMTQVQCKETLQMLIDDGVVNTDKMGSSNFYWSFPSFEFDSKKDKIIEQTKLLSETKERIQSETKKIEQLKSERVESETRTKNLEKLQTLKDDNKSFKEELLLYADSSLIDDKKRDIKIAIAAVNRYTDNISSLRQFCDSKYNIRPSDFDTSFGIKPDMDYLEEYNFNDTPQPVNKKKRK", "length": 221 }, "evidence": [ { "id": "A0A8C2N339", "url": "https://omabrowser.org/oma/group/A0A8C2N339/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6DC61-1", "protein_name": "Meiotic nuclear division protein 1 homolog", "gene_name": "mnd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSKKKGLSLEEKRSRMMEIFFETKDVFQLKDIEKIAPKSKGITPMSVKEVLQSLVDDNMVDTERVGTSNYYWAFPSKALHARKRRLEELEKQLEDGSQRKKALQQAVDKAKVGREVNEEREDLLKELTALKGQRDQMKVEIEKYQECDPAVVEEIRNANIAAKEAVARWTGGTFGNYLISYLLTCSLTRQEPWAHHLSPSSGFSPGTACQTCYYYQQAIS", "length": 220 }, "evidence": [ { "id": "A0A8C2N339", "url": "https://omabrowser.org/oma/group/A0A8C2N339/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8GYD2-1", "protein_name": "Meiotic nuclear division protein 1 homolog", "gene_name": "MND1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSKKRGLSLEEKREKMLQIFYESQDFFLLKELEKMGPKKGVISQSVKDVIQSLVDDDLVAKDKIGISIYFWSLPSCAGNQLRSVRQKLESDLQGSNKRLAELVDQCEALKKGREESEERTEALTQLKDIEKKHKDLKNEMVQFADNDPATLEAKRNAIEVAHQSANRWTDNIFTLRQWCSNNFPQAKEQLEHLYTEAGITEDFDYIELSSFPLSSSHEADTAKQLVQDEA", "length": 230 }, "evidence": [ { "id": "A0A8C2N339", "url": "https://omabrowser.org/oma/group/A0A8C2N339/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8K396-1", "protein_name": "Meiotic nuclear division protein 1 homolog", "gene_name": "Mnd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKKRGLSGEEKRTRMMEIFFETKDVFQLKDLEKLAPKEKGITAMSVKEVLQSLVDDGMVDCERIGTSNYYWAFPSKALHARKRKLEALNSQLSEGSQKHADLQKSIEKARVGRQETEERAMLAKELSSFRDQRQQLKAEVEKYRECDPQVVEEIREANKVAKEAANRWTDNIFAIKSWAKRKFGFEESKIDKNFGIPEDFDYID", "length": 205 }, "evidence": [ { "id": "A0A8C2N339", "url": "https://omabrowser.org/oma/group/A0A8C2N339/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BWT6-1", "protein_name": "Meiotic nuclear division protein 1 homolog", "gene_name": "MND1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKKKGLSAEEKRTRMMEIFSETKDVFQLKDLEKIAPKEKGITAMSVKEVLQSLVDDGMVDCERIGTSNYYWAFPSKALHARKHKLEVLESQLSEGSQKHASLQKSIEKAKIGRCETEERTRLAKELSSLRDQREQLKAEVEKYKDCDPQVVEEIRQANKVAKEAANRWTDNIFAIKSWAKRKFGFEENKIDRTFGIPEDFDYID", "length": 205 }, "evidence": [ { "id": "A0A8C2N339", "url": "https://omabrowser.org/oma/group/A0A8C2N339/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N339", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N339" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { 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This record is derived from a genomic sequence (NW_003615835.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003513333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513333" } ] }, { "annotation": "Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N369", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N369#function" }, { "database": "UniProtKB", "id": "RU365071", "url": "https://www.uniprot.org/uniprotkb/RU365071#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N369", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N369" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nsmce4a", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N369", "locus": {} } ], "crossref": [ { "id": "100774921", "url": "https://www.ncbi.nlm.nih.gov/gene/100774921", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774921", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774921", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FMGINRT", "url": "https://omabrowser.org/oma/group/FMGINRT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N369", "url": "https://www.orthodb.org/?gene=A0A8C2N369", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16140", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16140", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16140:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16140:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08743", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08743", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003513333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513333", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N369", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N369", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N369-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N369-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGDSSGRRPEGRGRGHDPHRDRTRSRSRSRSPLARRGAAPERREAAERPSLEDSEPSDSGDELMDPACLEAEYDQGLCRQIRHQYRALINSVQQNREDILNAGDKLTEVLEEANTLFNEVSRAREAVLDAQFLVLASDLGKEKAKQLRSDLSSFDMLRYVETLLTHMGVNPLEAEEFIRDEDRNDIELIVYDSWKISGKTAENTFNKTHTFHFLLGSIHGEFPVPKPRTDRPRQPRMIEEQRAMPAQLKCMEESHQEATEKEVERILGLLQTYFREDPDTPMSFFDFVVDPHSFPRTVENIFHVSFIIRDGFARIRLDQDRLPVIEPVINEESDGIEQNTQIRSQGIIALSYRDWEEIVKTFEISEPVISMSQSQQRLSA", "length": 381, "header": "tr|A0A8C2N369-1|A0A8C2N369_CRIGR Isoform 1 of Non-structural maintenance of chromosomes element 4 OS=Cricetulus griseus OX=10029 GN=Nsmce4a PE=3 SV=1 CANONICAL=A0A8C2N369-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N369-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N369/entry#A0A8C2N369-1", "sequence": { "sequence": "MSGDSSGRRPEGRGRGHDPHRDRTRSRSRSRSPLARRGAAPERREAAERPSLEDSEPSDSGDELMDPACLEAEYDQGLCRQIRHQYRALINSVQQNREDILNAGDKLTEVLEEANTLFNEVSRAREAVLDAQFLVLASDLGKEKAKQLRSDLSSFDMLRYVETLLTHMGVNPLEAEEFIRDEDRNDIELIVYDSWKISGKTAENTFNKTHTFHFLLGSIHGEFPVPKPRTDRPRQPRMIEEQRAMPAQLKCMEESHQEATEKEVERILGLLQTYFREDPDTPMSFFDFVVDPHSFPRTVENIFHVSFIIRDGFARIRLDQDRLPVIEPVINEESDGIEQNTQIRSQGIIALSYRDWEEIVKTFEISEPVISMSQSQQRLSA", "length": 381, "header": "tr|A0A8C2N369-1|A0A8C2N369_CRIGR Isoform 1 of Non-structural maintenance of chromosomes element 4 OS=Cricetulus griseus OX=10029 GN=Nsmce4a PE=3 SV=1 CANONICAL=A0A8C2N369-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N369", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N369" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N369", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N369" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774921", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774921", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z9K8-1", "protein_name": "Non-structural maintenance of chromosomes element 4", "gene_name": "Nsmce4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDSSGRRSEGRGRGRDPHRDRTRSRSRSRSPLARRGAAPERREAAERPSLEDTEPSDSGDELMDPACLEAEYDQGLCRQIRHQYRALINSVQQNREDILNAGDKLTEVLEEANTLFNEVSRAREAVLDAQFLVLASDLGKEKAKQLRSDLSSFDMLRYVETLLTHMGVNPLEAEEFIRDEDRTDIELIVYDSWKISGKTAENTFNKTHTFHFLLGSIHGEFPVPKPRTDRPRQPRMIEEQRAMPAQLKCMEESHQEATEKEVERILGLLQTYFREDPDTPMSFFDFVVDPHSFPRTVENIFHVSFIIRDGFARIRLDQDRLPIIEPVINEESEGIDQNIQFRSQGIIALSYHDWEEIVKTFEISEPVISLSQSQQRLSA", "length": 381 }, "evidence": [ { "id": "A0A8C2N369", "url": "https://omabrowser.org/oma/group/A0A8C2N369/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3XA30-1", "protein_name": "Non-structural maintenance of chromosomes element 4", "gene_name": "Nsmce4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGDSSGRRSEGRGRGRDPHRDRTRSRSRSRSPLARRGAAPERREAAERPSLEDSDLSDSGDELMDPACLEAEYDQGLCRQIRHQYRALINSVQQNREDILNAGDKLTEVLEEANTLFNEVSRAREAVLDAQFLVLASDLGKEKAKQLRSDLSSFDMLRYVETLLTHMGVNPLEAQEVIRDEDRADIELIVYDSWKISGKTAENTFNKTHTFHFLLGSIHGEFPVPKPRSDRPRQPRMIEEQRAMPAQLKCMEESHQEATEKEVERILGLLQTYFREDPDTPMSFFDFVVDPHSFPRTVENIFHVSFIIRDGFARIRLDQDRLPIIEPVINEESEGIDHNIQIRSQGIIALSYHDWEEIVKTFEISEPVIPLSQSQQRLSA", "length": 381 }, "evidence": [ { "id": "A0A8C2N369", "url": "https://omabrowser.org/oma/group/A0A8C2N369/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q2TBI1-1", "protein_name": "Non-structural maintenance of chromosomes element 4 homolog A", "gene_name": "NSMCE4A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGDSSGRRPEGRGRGRDPHRDRTRSRSRSRSPLSPGSRRGAAPERREAPERPGLEDTEPSDSGDEMIDPASLEEETDPSLCRQIRHQYRALINSVQQNREDILNASDKLTEVLEEANTLFNGVSRAREAVLDAHFLVLASDLGKEKAKQLRSDLNSFDMLRYVETLLTHMGVNPLEAEELIRDEDSSDLEFIVYDSWKISGKTAENTFNKTHTFHFLLGSIQGECPVPKPRIERPRKVRMIEEQQAMPAQLKRMEESHQEATEKEVERILGLLQTYFQEDPDTPMSFFDFVVDPHSFPRTVENIFHVSFIIRDGFARIRLDRDRLPVIEPVNINEESGGNTQIRNQAIIALSYRDWEEIVRTFEISEPVITSSQSQQRLSA", "length": 382 }, "evidence": [ { "id": "A0A8C2N369", "url": "https://omabrowser.org/oma/group/A0A8C2N369/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54T56-1", "protein_name": "Non-structural maintenance of chromosomes element 4", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNRNNSNGVGSSTGAGSSQSGIDNNNNNNNNSNNNNNRQQDESPNSKKVVKKQQQTIGERRELRKKYRTLIQDVSGNKSELILPSSDGLLRSLKKADNLYNNVLQAREAVLDSELLALASQFGVEQAQKFKVSLNGFDSFGLVNRYKERLTFYTDENNNNNSTINKTGWEKLSQLYHTHFHTVPDFDFMYGPINFEPEEKKVRAPRKLTQKDQPVGAAKHAEKITDTSNQVESETTSSRVQVMKQYIEKNPGKSFIDLVVDETSFAQTVENIFYFSFLLKDGHVKIAKDNEEMIIQTTLPPEEKDYQSKNAQLTHSVVKLDFNTWNDLKDISDLSFHMEEELQQFKNRRGGGGGGGSSTQTHTSTRK", "length": 367 }, "evidence": [ { "id": "A0A8C2N369", "url": "https://omabrowser.org/oma/group/A0A8C2N369/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9NXX6-1", "protein_name": "Non-structural maintenance of chromosomes element 4 homolog A", "gene_name": "NSMCE4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"site_annotation": [ { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N369", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N369" }, { "id": "PF08743", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08743" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Non-structural maintenance of chromosome element 4 C-terminal", "eco_id": "ECO_0000259", "start_pos": 282, "end_pos": 370, "start_aa": "Pro", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N369", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N369" }, { "id": "PF15412", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15412" } ], "ann_type": 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:: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614359.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007646098", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646098" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N378", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N378" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rhobtb1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N378", "locus": {} } ], "crossref": [ { "id": "cd01873", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01873", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18358", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18358", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767011", "url": "https://www.ncbi.nlm.nih.gov/gene/100767011", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767011", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767011", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YLDETQC", "url": "https://omabrowser.org/oma/group/YLDETQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N378", "url": "https://www.orthodb.org/?gene=A0A8C2N378", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24072", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24072", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007646098", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646098", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N378", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N378", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N378-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N378-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTDMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDEVSISLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKTMWYQEIKHFCPRTPVVLVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGIPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKVPECPSAGTSDAACLLDNPLCADVLFVLQGQEHIFAHRIYLATSSSKFYDLFLMECEESPGWGGGAGEEMPCRDFQGRTQSIGPAEEGKKSSQRTLQAAGPGASSVQDLLESLALQTEASGSEAQALTGWSKGFVSMHREARVNPISKRVGPVTVVRLDSSMQSGPFRTLLRFLYTGQLDEKEKDLLGLAQMAEVLEMFDLRMMVENIMNKEAFMNQEITKAFHVRKANRIKECLSKGTFSDVTFTLDDGAISAHKPLLICSCEWMAAMFGGSFVESANSEVHLPSINKMSMQAVLEYLYTKQLSPNLDLDPLELIALANRFCLPHLVALVEQHAVQELTKAAMSGVGIDGEVLSYLELAQFHNANQLAAWCLHHICTNYNSVCSKFRKEIKSKSTDNQEYFERHRWPPVWYLKEEDHYQRVKREREKEDLALKKHYSRRKWCFWHSSPAVA", "length": 696, "header": "tr|A0A8C2N378-1|A0A8C2N378_CRIGR Isoform 1 of Rho-related BTB domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Rhobtb1 PE=3 SV=1 CANONICAL=A0A8C2N378-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N378-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N378/entry#A0A8C2N378-1", "sequence": { "sequence": "MDTDMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDEVSISLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKTMWYQEIKHFCPRTPVVLVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGIPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKVPECPSAGTSDAACLLDNPLCADVLFVLQGQEHIFAHRIYLATSSSKFYDLFLMECEESPGWGGGAGEEMPCRDFQGRTQSIGPAEEGKKSSQRTLQAAGPGASSVQDLLESLALQTEASGSEAQALTGWSKGFVSMHREARVNPISKRVGPVTVVRLDSSMQSGPFRTLLRFLYTGQLDEKEKDLLGLAQMAEVLEMFDLRMMVENIMNKEAFMNQEITKAFHVRKANRIKECLSKGTFSDVTFTLDDGAISAHKPLLICSCEWMAAMFGGSFVESANSEVHLPSINKMSMQAVLEYLYTKQLSPNLDLDPLELIALANRFCLPHLVALVEQHAVQELTKAAMSGVGIDGEVLSYLELAQFHNANQLAAWCLHHICTNYNSVCSKFRKEIKSKSTDNQEYFERHRWPPVWYLKEEDHYQRVKREREKEDLALKKHYSRRKWCFWHSSPAVA", "length": 696, "header": "tr|A0A8C2N378-1|A0A8C2N378_CRIGR Isoform 1 of Rho-related BTB domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Rhobtb1 PE=3 SV=1 CANONICAL=A0A8C2N378-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N378", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N378" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N378", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N378" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767011", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767011", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AL07-1", "protein_name": "Rho-related BTB domain-containing protein 1", "gene_name": "RHOBTB1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDTDMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKTMWYQEIKHFCPRTPVVLVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGIPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKVPECPSMGTKEAACLLDNPLCADVLFVLQGQEQIFAHRIYLATSSSKFYDLFLMECEETPNWSEGACEREKPSLDFQAQELSLDLNEEREEGSPRTPQADQRTSPSQNVLQPEGPGLEAEGTVVETQSLSGWSKGFLGMHREMQVNPISKRVGPVTVVRMDASVQPGPFRTLLQFLYTGQLDEKEKDLMGLAQIAEVLEMFDLRMMVENIMNKEAFMNQEITKAFHVRKANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCKWMAAMFGGSFVESANSEVYLPNINKMSMQAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQELTKAAMSGVGIDGEVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQAYFERHRWPPVWYLKEEDHYQRVKREREKEDIALNKHHSRRKWCFWNSSPAVA", "length": 698 }, "evidence": [ { "id": "A0A8C2N378", "url": "https://omabrowser.org/oma/group/A0A8C2N378/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M1RSW5-1", "protein_name": "Rho-related BTB domain-containing protein 1", "gene_name": "rhobtb1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYLEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLSRPIKPGDILPPESGREVAKELGIPYYETSVFDQFGIKDIFDNAIRAALISRRHLQFWKSHLRRVQKPLLQAPFLPPKAPPPLIKIPECPAKNRDGPKQLLETPLCADVMFIVQEHVHLYAHRIYLSTSSSKFFDLFQMDFSDESQCLVVTERHGRDQLMRTLSLDTEEDVMVLPNLSPCSLRASKSDGTLKMLSFSGMHRRTRLSLASWSKAFYSIHKENVINPVTGTPALMTIVKMDHSIHHGPFSAVLRFLYTGELDEKEKDLMKIAQIAEILEVFDLRMMVENIMNNEGFMNQEITKAFHVRKANRIKECLAKNNFTDVVFRLDDGTINAHKPLLISSCDWMAALFGGSFMESANDEVSFPNTSRVCMQAVLEYLYTNQLSPMADLDPMELIALANRLCLPRLIALTEQYAVSELLKASKDGQDIDGEVLTYLELAQFHNANQLAAWCLHHICTHYNRICANYRKEIKSKSPENQEYFEKHRWPPVWYLKEEDHYQRVKKEREKEDVVLNKHHSRRRWCFWSTSPAVA", "length": 687 }, "evidence": [ { "id": "A0A8C2N378", "url": "https://omabrowser.org/oma/group/A0A8C2N378/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZD37-1", "protein_name": "Rho-related BTB domain-containing protein 1", "gene_name": "Rhobtb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDEVSISLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKTMWYQEIKHFCPRTPVVLVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGIPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKVPECPSTGTSDAACLLDNPLCADVLFILHDQEHIFAHRIYLATSSSKFYDLFLMECEDSPGWSGGAGEEVPCRDFQGRTQSLGAAEEGQEGSQRTPQADPGASSGQDLLESLASQTDASVSEAHALTGWSKGFVSMHREVRVNPISKRVGPVTVVRLDSSMQSGPFRTLLRFLYSGQLDEKEKDLLGLAQMAEVLEMFDLRMMVENIMNKEAFMNQEITKAFHVRKANRIKECLSKGTFSDVTFTLDDGAISAHKPLLICSCEWMAAMFGGSFVESTNSEVHLPNINKMSMQAVLEYLYTKQLSPNLDLDPLELIALANRFCLTHLVALVEQHAVQELTKAAVSGVSIDGEVLSYLELAQFHNANQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVWYLKEEDHYQRVKREREKEDLALNKHHSRRKWCFWHPSPAVA", "length": 695 }, "evidence": [ { "id": "A0A8C2N378", "url": "https://omabrowser.org/oma/group/A0A8C2N378/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MIH7-1", "protein_name": "Rho-related BTB domain-containing protein 1", "gene_name": "RHOBTB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKTMWYQEIKHFCPRTPVVLVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGIPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKVPECPSTGTNEAACLLDNPLCADVLFILQDQEQIFAHRIYLATSSSKFYDLFLMECEETPHWSEGACEREKQSRDSQEWAQSLDPDEEREEGTPRTPQADQWTPSSQNLSQQETLGLDAEDLVAETQTLLGWSKGFIGMHKEMQVNPVSKRLGPVTVVRMDASVQPGPFRTLLQFLYTGQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQEITKAFHVRKANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCKWMAAMFGGSFVESANSEVYLPNINKMSMQAVLDYLYTKHLPPNLDLDPLELIALANRFCLPHLVALAEQHAVQELTKAAMSGVGIDGEVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVWYLKEEDHYQRVKREREKEDIALNKHHSRRKWCFWNSSPAVA", "length": 698 }, "evidence": [ { "id": "A0A8C2N378", "url": "https://omabrowser.org/oma/group/A0A8C2N378/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O94844-1", "protein_name": "Rho-related BTB domain-containing protein 1", "gene_name": "RHOBTB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMECEESPNGSEGACEKEKQSRDFQGRILSVDPEEEREEGPPRIPQADQWKSSNKSLVEALGLEAEGAVPETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVRMDASVQPGPFRTLLQFLYTGQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQEITKAFHVRKANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVESANSEVYLPNINKISMQAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQELTKAATSGVGIDGEVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVWYLKEEDHYQRVKREREKEDIALNKHRSRRKWCFWNSSPAVA", "length": 696 }, "evidence": [ { "id": "A0A8C2N378", "url": "https://omabrowser.org/oma/group/A0A8C2N378/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DAK3-1", "protein_name": "Rho-related BTB domain-containing protein 1", "gene_name": "Rhobtb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDEVSISLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKTMWYQEIKHFCPRTPVVLVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGIPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKVPECPSAGTSDAACLLDNPLCADVLFVLHDEEHIFAHRIYLATSSSKFYDLFLMECEESPCWGGGAGEEVPCRDFQGRTQSLGSAEEGKEGPQRTPQADPGASSGQDLPESLALQMEASGSEGHALSGWSKGFVSMHREVRVNPISKRVGPVTVVRLDPSMQSGPFRTLLRFLYSGQLDEKEKDLLGLAQMAEVLEMFDLRMMVENIMNKEAFMNQEITKAFHVRKANRIKECLSKGTFSDVTFTLDDGAISAHKPLLICSCEWMAAMFGGSFVESANREVHLPNINKMSMQAVLEYLYTKQLSPNLDLDPLELIALANRFCLTHLVALVEQHAVQELTKAAVSGVSIDGEVLSYLELAQFHNANQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVWYLKEEDHYQRVKREREKEDLALNKHHSRRKWCFWHSSPAVA", "length": 695 }, "evidence": [ { "id": "A0A8C2N378", "url": "https://omabrowser.org/oma/group/A0A8C2N378/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N378", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N378" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N378", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N378" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N378", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N378" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N378", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N378" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N378", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N378" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 266, "end_pos": 427, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 37, "end_pos": 39 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FGD9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FGD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GN04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GN04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GN04-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GN04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GNE2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GNE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JAD6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JAD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JE18", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JE18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JE18-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JE18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGD1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGD1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATASPAADGGRGRPWEGGLVSWPPAPPLTLPWTWMGPSWGQHPGHWGFPALTDPSASPAASLGIFEVRRVLDASGCSMLAPLQTGAARFSSYLLSRARKVLGSHLFSPCGVPEFCSISTRKLAAHGFGASMAAMVPFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPRLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCHYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSKPF", "length": 337, "header": "tr|A0A8C2N3C1-1|A0A8C2N3C1_CRIGR Isoform 1 of ERI1 exoribonuclease 3 OS=Cricetulus griseus OX=10029 GN=Eri3 PE=4 SV=1 CANONICAL=A0A8C2N3C1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N3C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C1/entry#A0A8C2N3C1-1", "sequence": { "sequence": "MATASPAADGGRGRPWEGGLVSWPPAPPLTLPWTWMGPSWGQHPGHWGFPALTDPSASPAASLGIFEVRRVLDASGCSMLAPLQTGAARFSSYLLSRARKVLGSHLFSPCGVPEFCSISTRKLAAHGFGASMAAMVPFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPRLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCHYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSKPF", "length": 337, "header": "tr|A0A8C2N3C1-1|A0A8C2N3C1_CRIGR Isoform 1 of ERI1 exoribonuclease 3 OS=Cricetulus griseus OX=10029 GN=Eri3 PE=4 SV=1 CANONICAL=A0A8C2N3C1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FGD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C1/entry#A0A9J7FGD9-1", "sequence": { "sequence": "MATASPAADGGRGRPWEGGLVSWPPAPPLTLPWTWMGPSWGQHPGHWGFPALTDPSASPAASLGIFEVRRVLDASGCSMLAPLQTGAARFSSYLLSRARKVLGSHLFSPCGVPEFCSISTRKLAAHGFGASMAAMVPFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPRLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCHYLGLPVADYFKQWINLKKMTARTLPTS", "length": 286, "header": "tr|A0A9J7FGD9-1|A0A8C2N3C1_CRIGR Computationally mapped isoform of ERI1 exoribonuclease 3 OS=Cricetulus griseus OX=10029 GN=Eri3 PE=4 SV=1 CANONICAL=A0A8C2N3C1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GN04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C1/entry#A0A9J7GN04-1", "sequence": { "sequence": "MLAPLQTGAARFSSYLLSRARKVLGSHLFSPCGVPEFCSISTRKLAAHGFGASMAAMVPFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPRLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCHYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSKPF", "length": 259, "header": "tr|A0A9J7GN04-1|A0A9J7GN04_CRIGR Computationally mapped isoform of ERI1 exoribonuclease 3 OS=Cricetulus griseus OX=10029 GN=Eri3 PE=4 SV=1 CANONICAL=A0A8C2N3C1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GNE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C1/entry#A0A9J7GNE2-1", "sequence": { "sequence": "MATASPAADGGRGRPWEGGLVSWPPAPPLTLPWTWMGPSWGQHPGHWGFPALTDPSASPAASLGIFEVRRVLDASGCSMLAPLQTGAARFSSYLLSRARKVLGSHLFSPCGVPEFCSISTRKLAAHGFGASMAAMVPFPPQRYHYFLVLDFEATCDKPQIHPQLTGIIQAMVDGQPRLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCHYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSKPF", "length": 298, "header": "tr|A0A9J7GNE2-1|A0A9J7GNE2_CRIGR Computationally mapped isoform of ERI1 exoribonuclease 3 isoform X7 OS=Cricetulus griseus OX=10029 GN=Eri3 PE=4 SV=1 CANONICAL=A0A8C2N3C1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JAD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C1/entry#A0A9J7JAD6-1", "sequence": { "sequence": "MATASPAADGGRGRPWEGGLVSWPPAPPLTLPWTWMGPSWGQHPGHWGFPALTDPSASPAASLGIFEVRRVLDASGCSMLAPLQTGAARFSSYLLSRARKVLGSHLFSPCGVPEFCSISTRKLAAHGFGASMAAMVPFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPRLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCHYLGLPVADYFKQWINLKKMS", "length": 279, "header": "tr|A0A9J7JAD6-1|A0A9J7JAD6_CRIGR Computationally mapped isoform of ERI1 exoribonuclease 3 isoform X9 OS=Cricetulus griseus OX=10029 GN=Eri3 PE=4 SV=1 CANONICAL=A0A8C2N3C1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JE18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C1/entry#A0A9J7JE18-1", "sequence": { "sequence": "MATASPAADGGRGRPWEGGLVSWPPAPPLTLPWTWMGPSWGQHPGHWGFPALTDPSASPAASLGIFEVRRDASGCSMLAPLQTGAARFSSYLLSRARKVLGSHLFSPCGVPEFCSISTRKLAAHGFGASMAAMVPFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPRLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCHYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSKPF", "length": 335, "header": "tr|A0A9J7JE18-1|A0A9J7JE18_CRIGR Computationally mapped isoform of ERI1 exoribonuclease 3 OS=Cricetulus griseus OX=10029 GN=Eri3 PE=4 SV=1 CANONICAL=A0A8C2N3C1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JGD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C1/entry#A0A9J7JGD1-1", "sequence": { "sequence": "MEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPRLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCHYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSKPF", "length": 160, "header": "tr|A0A9J7JGD1-1|A0A9J7JGD1_CRIGR Computationally mapped isoform of ERI1 exoribonuclease 3 isoform X4 OS=Cricetulus griseus OX=10029 GN=Eri3 PE=4 SV=1 CANONICAL=A0A8C2N3C1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FGD9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FGD9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756117", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756117", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3C1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C1" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3C1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C1" } ], "pmid": "" }, { "name": "3'-5'-RNA exonuclease activity", "id": "GO:0000175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3C1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C1" }, { "id": "SM00479", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00479" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exonuclease", "eco_id": "ECO_0000259", "start_pos": 145, "end_pos": 329, "start_aa": "Tyr", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N3C6-1", "uniprot_ac": "A0A8C2N3C6", "uniprot_id": "A0A8C2N3C6_CRIGR", "mass": { "chemical_mass": 117788.0, "monoisotopic_mass": 117788.0 }, "refseq": { "ac": "XP_027282568", "name": "small G protein signaling modulator 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282568" }, "gene_names": [ { "name": "Sgsm2", "type": "recommended", "evidence": [ { "id": "A0A8C2N3C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C6" } ] }, { "name": "Sgsm2", "type": "synonym", "evidence": [ { "id": "XP_027282568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282568" } ] } ], "protein_names": [ { "name": "Small G protein signaling modulator 2 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A8C2N3C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C6/entry#names_and_taxonomy" } ] }, { "name": "small G protein signaling modulator 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027282568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282568" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282568" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3C6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sgsm2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C6", "locus": {} } ], "crossref": [ { "id": "cd15784", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15784", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17704", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17704", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767108", "url": "https://www.ncbi.nlm.nih.gov/gene/100767108", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021935", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021935", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037745", "url": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12068", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12068", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027282568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282568", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N3C6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N3C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N6C1-1", "url": 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"length": 1046, "header": "tr|A0A8C2N3C6-1|A0A8C2N3C6_CRIGR Isoform 1 of Small G protein signaling modulator 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Sgsm2 PE=3 SV=1 CANONICAL=A0A8C2N3C6-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N6C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C6/entry#A0A8C2N6C1-1", "sequence": { "sequence": "MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAAGFLRSDKMAALFTKVGKTCPVAGEVCHKVQELQQQAEGRKPSGSSQEALRKQGSTSGKAPALSPQALKHIWVRTALMEKVLDRVVQYLAENCSKYYEKEALLADPVFGPVLACLLVGPCALEYTKLKTADHYWTDPSADELVQRHRIRGPPNRQDSPAKRPALGIRKRHSSGSASEDRLAACAREYVESLHQNSRTRLLYGKNNVLVQPKEDMEAVPGYLSLHQSAENLTLKWTPNQLMNGTLGDSELEKSVYWDYALVVPFSQIVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHLLSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDVEELGVGRATDYVFRIIYPGHRHEHNAGDMIEMQGFGPNLTAWHLEPLCSQGSSCLSCSSSSSPYATPSHCSCIPDRLPLRLLCESMKRQIVSRAFYGWLAYCRHLSTVRTHLSALVHHNIIPPDRPPGASGGLTKDVWSKYQKDKKNYKELELLRQVYCGGVEHEIRKDVWPFLLGHYKFGMSKKEMEQVDTAVAVRYQQVLAEWKACEVVVRQREAHPATLTKFSSGSSIDSHVQRLVHRDSTISNDVFISVDDLEPPGPQDPEDSRPKQEQEPATGTPGMAEQQSVEFDSPDSGLPSSRNYSVASGIQSSLDEAQSVGFEEDGGGEEGSSEGPTTAAHTVSEPHEPGQKLAPASELEAGEELAAVCAAAYTIELLDTVALNLHRIDKDVQRCDRNYWYFTTPNLERLRDIMCSYVWEHLEVGYVQGMCDLLAPLLVILDDDQLAYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIKFFNERAERHDAQEILRIARDLVHKVQMLIDTK", "length": 1001, "header": "tr|A0A8C2N6C1-1|A0A8C2N3C6_CRIGR Computationally mapped isoform of Small G protein signaling modulator 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Sgsm2 PE=3 SV=1 CANONICAL=A0A8C2N3C6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 516, "start_aa": "Thr", "end_pos": 516, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr516", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 729, "start_aa": "Thr", "end_pos": 729, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr729", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 786, "start_aa": "Thr", "end_pos": 786, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr786", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6C1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6C1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767108", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767108", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3C6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C6" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3C6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3C6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C6" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3C6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "late endosome to Golgi transport", "id": "GO:0034499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034499", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3C6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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[ "Protein Classification" ] }, { "id": "PTHR11731", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11731", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11731:SF98", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11731:SF98", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00930", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00930", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027267147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267147", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N3F3", 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"MKIQSGKCNMAAAMETEQLGVEIFETAECEEGTIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRTDPDSPHSDRVYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIAAYDYHPGSGTFLFQAGSGIYHIKDGGPHGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNLVTREERRITYVHNELANMEEDPRSAGVATFVLQEEFDRYSGYWWCPQAERTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEILVDAEGGIIDVIDKELVQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTHLQIVLISPELFIPVEDDAMDRQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQTHEDEIEFIFASECKTGFRHLYKIISILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIWIDEVRKLVYFEGTKDSPLEHHLYVTSYANPGEVVRLTDRGYSHSCCLSQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPVHKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASQYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI", "length": 892, "header": "tr|A0A8C2N3F3-1|A0A8C2N3F3_CRIGR Isoform 1 of dipeptidyl-peptidase IV OS=Cricetulus griseus OX=10029 GN=Dpp8 PE=3 SV=1 CANONICAL=A0A8C2N3F3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N3F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F3/entry#A0A8C2N3F3-1", "sequence": { "sequence": "MKIQSGKCNMAAAMETEQLGVEIFETAECEEGTIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRTDPDSPHSDRVYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIAAYDYHPGSGTFLFQAGSGIYHIKDGGPHGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNLVTREERRITYVHNELANMEEDPRSAGVATFVLQEEFDRYSGYWWCPQAERTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEILVDAEGGIIDVIDKELVQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTHLQIVLISPELFIPVEDDAMDRQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQTHEDEIEFIFASECKTGFRHLYKIISILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIWIDEVRKLVYFEGTKDSPLEHHLYVTSYANPGEVVRLTDRGYSHSCCLSQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPVHKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASQYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI", "length": 892, "header": "tr|A0A8C2N3F3-1|A0A8C2N3F3_CRIGR Isoform 1 of dipeptidyl-peptidase IV OS=Cricetulus griseus OX=10029 GN=Dpp8 PE=3 SV=1 CANONICAL=A0A8C2N3F3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GXF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F3/entry#A0A9J7GXF5-1", "sequence": { "sequence": "MKIQSGKCNMAAAMETEQLGVEIFETAECEEGTIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRTDPDSPHSDRVYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIAAYDYHPGSGTFLFQAGSGIYHIKDGGPHGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNLVTREERRITYVHNELANMEEDPRSAGVATFVLQEEFDRYSGYWWCPQAERTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEILVDAEGGIIDVIDKELVQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTHLQIVLISPELFIPVEDDAMDRQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQTHEDEIEFIFASECKTGFRHLYKIISILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIWIDEVRKLVYFEGTKDSPLEHHLYVTSYANPGEVVRLTDRGYSHSCCLSQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPVHKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMEALNATF", "length": 723, "header": "tr|A0A9J7GXF5-1|A0A9J7GXF5_CRIGR Computationally mapped isoform of dipeptidyl-peptidase IV OS=Cricetulus griseus OX=10029 GN=Dpp8 PE=3 SV=1 CANONICAL=A0A8C2N3F3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3F3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3F3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773914", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773914", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5P801-1", "protein_name": "dipeptidyl-peptidase IV", "gene_name": "DPP8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAMETEQPGLEVFETAGCEEQVQREEQPKPEPFYVERHSWSQLRKLLTDTRKYHGYMMAKAPHDFTFVKKNDPEGPHSDRIYYLAMSGENRENTLFYSEIPKTVNKAAVLLLSWKPLLDLFPAILDYGMYSREEELLRERKRIGTVGIASYDYHRESGTFLFQAGSGIYHVKDGGPHGFTQQPLRPILVETSCPNIRMDPKLCPADPNWIAFIHSNDIWISNIETREERRLTFVHNELANVEEDPKSAGVATFVLQEEFDRYTGYWWSPKAEPTLNGGKVLRILYEENDESEVEIIHVTSPMLETRRTDSFRYPKTGTANPKVTFKISEVVINEEGRIADVVDKELVQPFEILFEGVEYIARAGWTPEGKYVWSILLDRSQTRLQIVLIPPALFIPVEDDAMERQKLIDAVPDSVTPLIIYEETTDIWINIHDIFHVFPQTHEDEIEFIFASECKTGFRHLYKIVSVLKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIYVDEAKKLVYFQGTKDSPLEHHLYVVNYKNPGEVKRLTERGYSHACCVSQDCDMFISKYSNQKNPHCVSLYRLTGHEDDAAQRTKEFWATILDSAGPLPDYIPPEVFSFESSTGFTLYGMMYKPHNLQPGKKYPTVIFIYGGPQVQLVNNRFKGLKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLHYLASQYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPEHNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLYYLQENLGSRIAALKAM", "length": 882 }, "evidence": [ { "id": "A0A8C2N3F3", "url": "https://omabrowser.org/oma/group/A0A8C2N3F3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1N1L4-1", "protein_name": "dipeptidyl-peptidase IV", "gene_name": "DPP8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWKRSEQMKIQSGKCNMAAAMETEQLGVEIFETAECEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDPRSAGVATFVLQEEFDRYSGYWWCPEAETTPSGSRILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEILIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWAILLDRSQTRLQIVLISPELFIPVEDDAMERQRFIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEDEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRKLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISRHCDFFISKYSNQKSPHCVSLYKLSSPDDDPTCKTKEFWATLLDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASQYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI", "length": 898 }, "evidence": [ { "id": "A0A8C2N3F3", "url": "https://omabrowser.org/oma/group/A0A8C2N3F3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6V1X1-1", "protein_name": "Dipeptidyl peptidase 8", "gene_name": "DPP8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI", "length": 898 }, "evidence": [ { "id": "A0A8C2N3F3", "url": "https://omabrowser.org/oma/group/A0A8C2N3F3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80YA7-1", "protein_name": "Dipeptidyl peptidase 8", "gene_name": "Dpp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIPSGRCNMAAAMETEQLGVEIFETAECEEGNGESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRTDPDGPHSDRVYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIAAYDYHPGSGTFLFQAGSGIYHIKDGGPHGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNLVTREERRITYVHNELANMEEDPRSAGVATFVLQEEFDRYSGYWWCPQAERTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIVVDAAGGIIDVIDKELVQPFEILFEGVEYIARAGWTPEGKHAWSILLDRSQTHLQIVLISPELFIPVEDDAMDRQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQTHEDEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEITITSGEWEVLGRHGSNIWVDEARKLVYFEGTKDSPLEHHLYVTSYANPGEVVRLTDRGYSHSCCLSRHCDFFISKYSNQKNPHCVSLYKLSSPEDDPVHKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASQYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI", "length": 892 }, "evidence": [ { "id": "A0A8C2N3F3", "url": "https://omabrowser.org/oma/group/A0A8C2N3F3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "dipeptidyl-peptidase activity", "id": "GO:0008239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008239", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3F3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F3" } ], "pmid": "" }, { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3F3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F3" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3F3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3F3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N3F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F3" }, { "id": "PF19520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dipeptidyl peptidase 8 /9 ,N-terminal", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 156, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N3F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F3" }, { "id": "PF00930", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00930" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dipeptidylpeptidase IV N-terminal", "eco_id": "ECO_0000259", "start_pos": 170, "end_pos": 588, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N3F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F3" }, { "id": "PF00326", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00326" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S9 prolyl oligopeptidase catalytic", "eco_id": "ECO_0000259", "start_pos": 681, "end_pos": 884, "start_aa": "Phe", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.14.5", "ec_name": "Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.", "evidence": [ { "id": "3.4.14.5", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.14.5" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N3F8-1", "uniprot_ac": "A0A8C2N3F8", "uniprot_id": "A0A8C2N3F8_CRIGR", "mass": { "chemical_mass": 52504.0, "monoisotopic_mass": 52504.0 }, "refseq": { "ac": "XP_003495056", "name": "orexin receptor type 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495056" }, "gene_names": [ { "name": "Hcrtr2", "type": "recommended", "evidence": [ { "id": "A0A8C2N3F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F8" } ] }, { "name": "Hcrtr2", "type": "synonym", "evidence": [ { "id": "XP_003495056", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495056" } ] } ], "protein_names": [ { "name": "Orexin receptor type 2", "type": "recommended", "evidence": [ { "id": "A0A8C2N3F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F8/entry#names_and_taxonomy" } ] }, { "name": "Hypocretin receptor type 2", "type": "synonym", "evidence": [ { "id": "A0A8C2N3F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F8/entry#names_and_taxonomy" } ] }, { "name": "orexin receptor type 2", "type": "synonym", "evidence": [ { "id": "XP_003495056", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495056" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613582.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003495056.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003495056", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495056" } ] }, { "annotation": "G-protein coupled receptor that binds neuropeptides orexin-A and orexin-B, two neuropeptides derived from a common precursor, prepro-orexin. Upon neuropeptide ligand binding, HCRTR2 can couple with both G(q)/11 and G(i)/o heterotrimeric G-proteins thereby initiating distinct downstream signaling cascades. Involved in regulating the sleep-wake cycle. Contributes to central regulation of glucose homeostasis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3F8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F8#function" }, { "database": "UniProtKB", "id": "ARBA00094467", "url": "https://www.uniprot.org/uniprotkb/ARBA00094467#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3F8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Hcrtr2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F8", "locus": {} } ], "crossref": [ { "id": "cd15208", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15208", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762569", "url": "https://www.ncbi.nlm.nih.gov/gene/100762569", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762569", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762569", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LHIPGMN", "url": "https://omabrowser.org/oma/group/LHIPGMN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N3F8", "url": "https://www.orthodb.org/?gene=A0A8C2N3F8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03827", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03827", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003495056", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495056", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N3F8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N3F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSTKLEDSLPRRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQAIVMECSSMLPGLANKTTLFTVCDEHWGGDVYPKMYHICFFLVTYMAPLCLMILAYLQIFRKLWCRQIPGTSSVVQRKWKQPQMVSQPRGSGQQSKARISAVAAEIKQIRARRKTARMLMVVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCLGVHHRQGDRLARGRTSTESRKSLTTQISNFDNVSKLSEHVVLTSLSTLPTANGTGPLQNWYLQQGVPSSLLSTWLEV", "length": 460, "header": "tr|A0A8C2N3F8-1|A0A8C2N3F8_CRIGR Isoform 1 of Orexin receptor type 2 OS=Cricetulus griseus OX=10029 GN=Hcrtr2 PE=3 SV=1 CANONICAL=A0A8C2N3F8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N3F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F8/entry#A0A8C2N3F8-1", "sequence": { "sequence": "MSSTKLEDSLPRRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQAIVMECSSMLPGLANKTTLFTVCDEHWGGDVYPKMYHICFFLVTYMAPLCLMILAYLQIFRKLWCRQIPGTSSVVQRKWKQPQMVSQPRGSGQQSKARISAVAAEIKQIRARRKTARMLMVVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCLGVHHRQGDRLARGRTSTESRKSLTTQISNFDNVSKLSEHVVLTSLSTLPTANGTGPLQNWYLQQGVPSSLLSTWLEV", "length": 460, "header": "tr|A0A8C2N3F8-1|A0A8C2N3F8_CRIGR Isoform 1 of Orexin receptor type 2 OS=Cricetulus griseus OX=10029 GN=Hcrtr2 PE=3 SV=1 CANONICAL=A0A8C2N3F8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3F8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3F8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762569", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762569", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MG23-1", "protein_name": "Orexin receptor type 2", "gene_name": "HCRTR2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGTKLEDSPPCRNWSSAPELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCVIMIPQAIVMECSTMLPGLANKTALFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKALQPLSQPRGPGQQTKSRISAVAAEIKQIRARRKTARMLMVVLLVFAICYLPISILNVLKRVFGMFTHTEDRETVYAWFTFAHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLARGRTSTESRKSLTTQISNFDNVSKLSEQVVLTSISTLPAANGAGPLQNW", "length": 444 }, "evidence": [ { "id": "A0A8C2N3F8", "url": "https://omabrowser.org/oma/group/A0A8C2N3F8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O43614-1", "protein_name": "Orexin receptor type 2", "gene_name": "HCRTR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKLSEQVVLTSISTLPAANGAGPLQNW", "length": 444 }, "evidence": [ { "id": "A0A8C2N3F8", "url": "https://omabrowser.org/oma/group/A0A8C2N3F8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O62809-1", "protein_name": "Orexin receptor type 2", "gene_name": "HCRTR2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGTKLEDSPPCRNWSSAPELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQAIVMECSTMLPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQQTKSRISAVAAEIKQIRARRKTARMLMVVLLVFAICYLPISILNVLKRVFGMFTHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLARGRTSTESRKSLTTQISNFDNISKLSEQVLLTSMSTLPAANGAGQLQNW", "length": 444 }, "evidence": [ { "id": "A0A8C2N3F8", "url": "https://omabrowser.org/oma/group/A0A8C2N3F8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P56719-1", "protein_name": "Orexin receptor type 2", "gene_name": "Hcrtr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTKLEDSLPRRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVVIWIVSCIIMIPQAIVMERSSMLPGLANKTTLFTVCDERWGGEVYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKQPQPVSQPRGSGQQSKARISAVAAEIKQIRARRKTARMLMVVLLVFAICYLPISILNVLKRVFGMFTHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCLGVHRRQGDRLARGRTSTESRKSLTTQISNFDNVSKLSEHVALTSISTLPAANGAGPLQNWYLQQGVPSSLLSTWLEV", "length": 460 }, "evidence": [ { "id": "A0A8C2N3F8", "url": "https://omabrowser.org/oma/group/A0A8C2N3F8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P58308-1", "protein_name": "Orexin receptor type 2", "gene_name": "Hcrtr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTKLEDSLSRRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVVIWIVSCIIMIPQAIVMECSSMLPGLANKTTLFTVCDEHWGGEVYPKMYHICFFLVTYMAPLCLMILAYLQIFRKLWCRQIPGTSSVVQRKWKQQQPVSQPRGSGQQSKARISAVAAEIKQIRARRKTARMLMVVLLVFAICYLPISILNVLKRVFGMFTHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCLGVHHRQGDRLARGRTSTESRKSLTTQISNFDNVSKLSEHVVLTSISTLPAANGAGPLQNWYLQQGVPSSLLSTWLEV", "length": 460 }, "evidence": [ { "id": "A0A8C2N3F8", "url": "https://omabrowser.org/oma/group/A0A8C2N3F8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3F8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3F8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F8" } ], "pmid": "" }, { "name": "regulation of cytosolic calcium ion concentration", "id": "GO:0051480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051480", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3F8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F8" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3F8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3F8" } ], "pmid": "" }, { "name": "feeding behavior", "id": "GO:0007631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007631", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3F8", "url": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N3I1-1", "uniprot_ac": "A0A8C2N3I1", "uniprot_id": "A0A8C2N3I1_CRIGR", "mass": { "chemical_mass": 69840.0, "monoisotopic_mass": 69840.0 }, "refseq": { "ac": "XP_003501250", "name": "NUAK family SNF1-like kinase 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501250" }, "gene_names": [ { "name": "Nuak2", "type": "recommended", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] }, { "name": "Nuak2", "type": "synonym", "evidence": [ { "id": "XP_003501250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501250" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1/entry#names_and_taxonomy" } ] }, { "name": "NUAK family SNF1-like kinase 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003501250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501250" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613838.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003501250", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501250" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3I1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nuak2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1", "locus": {} } ], "crossref": [ { "id": "cd14161", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14161", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754593", "url": "https://www.ncbi.nlm.nih.gov/gene/100754593", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754593", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754593", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RPLMKKQ", "url": "https://omabrowser.org/oma/group/RPLMKKQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N3I1", "url": "https://www.orthodb.org/?gene=A0A8C2N3I1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346:SF93", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346:SF93", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003501250", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501250", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N3I1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N3I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1E8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1E8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1E8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1E8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESVAFPRRAGQAPSASALATERARALADGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERPRLSERDARHFFRQIVSALHYCHQNGVVHRDLKLENILLDANGNIKIADFGLSNLYHKGKFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKTLVKQISSGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASHWWVNWGYTTRVGEQEALRESGHLGGDSGRASMADWLRRSSRPLLENGAKVCSFFKQHVPGGGSTVPGLERQHSLKKSRKENDMAQTLQGDPAEDTAPRPGKSSLKLPKSILKKKASTSSGVVQEDPQELSPVPDTPGQPVPAVALLPRKGILKKSRQRESGYYSSPEPSESGELLDAAGDVFVNGDPVEQKSSQAAGHLLHRKGILKLNGKFSSTALESTTPSTFGSLDQLASPHPVTRASRPSGAVSEDSILSSESFDQLDLPDRLPETPLRGCVSVDNLRGLEQPPSEGLRRWWQEPLGDSCFSLTDCQEVTAAYRQALGICSKLS", "length": 632, "header": "tr|A0A8C2N3I1-1|A0A8C2N3I1_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Nuak2 PE=3 SV=1 CANONICAL=A0A8C2N3I1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N3I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1/entry#A0A8C2N3I1-1", "sequence": { "sequence": "MESVAFPRRAGQAPSASALATERARALADGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERPRLSERDARHFFRQIVSALHYCHQNGVVHRDLKLENILLDANGNIKIADFGLSNLYHKGKFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKTLVKQISSGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASHWWVNWGYTTRVGEQEALRESGHLGGDSGRASMADWLRRSSRPLLENGAKVCSFFKQHVPGGGSTVPGLERQHSLKKSRKENDMAQTLQGDPAEDTAPRPGKSSLKLPKSILKKKASTSSGVVQEDPQELSPVPDTPGQPVPAVALLPRKGILKKSRQRESGYYSSPEPSESGELLDAAGDVFVNGDPVEQKSSQAAGHLLHRKGILKLNGKFSSTALESTTPSTFGSLDQLASPHPVTRASRPSGAVSEDSILSSESFDQLDLPDRLPETPLRGCVSVDNLRGLEQPPSEGLRRWWQEPLGDSCFSLTDCQEVTAAYRQALGICSKLS", "length": 632, "header": "tr|A0A8C2N3I1-1|A0A8C2N3I1_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Nuak2 PE=3 SV=1 CANONICAL=A0A8C2N3I1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1E8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1/entry#A0A9J7G1E8-1", "sequence": { "sequence": "MSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERPRLSERDARHFFRQIVSALHYCHQNGVVHRDLKLENILLDANGNIKIADFGLSNLYHKGKFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKTLVKQISSGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASHWWVNWGYTTRVGEQEALRESGHLGGDSGRASMADWLRRSSRPLLENGAKVCSFFKQHVPGGGSTVPGLERQHSLKKSRKENDMAQTLQGDPAEDTAPRPGKSSLKLPKSILKKKASTSSGVVQEDPQELSPVPDTPGQPVPAVALLPRKGILKKSRQRESGYYSSPEPSESGELLDAAGDVFVNGDPVEQKSSQAAGHLLHRKGILKLNGKFSSTALESTTPSTFGSLDQLASPHPVTRASRPSGAVSEDSILSSESFDQLDLPDRLPETPLRGCVSVDNLRGLEQPPSEGLRRWWQEPLGDSCFSLTDCQEVTAAYRQALGICSKLS", "length": 525, "header": "tr|A0A9J7G1E8-1|A0A8C2N3I1_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Nuak2 PE=3 SV=1 CANONICAL=A0A8C2N3I1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1E8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1E8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1E8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1E8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754593", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754593", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A9S5-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "NUAK2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MERAAVGFGGTSLVEGFIKSPRPLMKKQAVKRHHHKHNLKHRYEFLETLGKGTYGKVKKARERSGKLVAIKSIRKDRIKDEQDLIHIRREIEIMSSLNHPHIIAVHEGRAQTSSALSIPPNAPVASPCSHPVFENSSKIVIVMEYASKGDLYDYISERQRLSEQEARHFFRQVVSAVYYCHKNGIVHRDLKLENILLDANGNIKIADFGLSNVYQQDKFLQTYCGSPLYASPEIINGRPYKGPEVDSWSLGVLLYILIHGTMPFDGHDYKTLVKQITSGDYREPTKLSDACGLIRWMLMVNPERRATIEDIATHWWVNWGYRVPVGEQELLRESSESPLATVAEWLRRSSRPLFENGSKVRCFLKQHIPGVALERQRSLKKSKKENDVSHALQEGAAAPENPSKSILKRPKGILKKRNSCEQKVPIPPPTAPGGEAKSEDGDVTAVGLSPVLPSAVLGGSEGSGVVSVAVPKKGILKKPPKRESGYYSSLECCESGDVLDAGSLDLEGNVFADSPTAERGSPVLPSSRKGILKHSSKYTSGAEPHSPPRQSFGCFDEVSLPKAPLAPRPRPPSAVSEDSILSTESFEQLDLPPRVPPGRSGAMRGCVSADSLLLLEEEEEVDEGRRLRRWTVTHCPTALGESRFSLESCDNVTEVHRRAVAISMKLS", "length": 667 }, "evidence": [ { "id": "A0A8C2N3I1", "url": "https://omabrowser.org/oma/group/A0A8C2N3I1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4FQG1-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "NUAK2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESLAFPRRLGPGPSATAALAAELVRPLADGLLKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKARESSGRLVAIKSIRKDRIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYIIERQRLSEREARHFFRQIVSAVHYCHQNGVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYMGPEVDSWSLGVLLYILVHGSMPFDGQDHKTLVKQISNGAYRQPPKPSDACGLIRWLLMVNPTRRATLEDVASHWWVNWGYATRVGEQEALHEGGHPSSDSGRASMADWLRRSSRPLLENGAKVCSFFKQHAPGAGSLTPGLERQHSLKKSRKENDMAQTLQGDPAADASPRPGRGNLKLPKGILKKKASTSSEGAREGPELSPVPAGPGQAAPLLPKKGILKKSRQRESGYYSSPEPSESGELLDAGDVFVSGDAVEHKPPEASGLLLHRKGILKHNGKFSRAALELTAPAFGSLDQLASPGPPARASRPSGAVSEDSILSSESFDQLDLPERLPEPPLRGCVSVDNLMGLEEPSEGPGSRGLRRWRQDPRGESCFSLMDCQEVTEAHQQALGVCTRFS", "length": 631 }, "evidence": [ { "id": "A0A8C2N3I1", "url": "https://omabrowser.org/oma/group/A0A8C2N3I1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q66HE5-1", "protein_name": "NUAK family SNF1-like kinase 2", "gene_name": "Nuak2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESVALHRRGNLAPSASALATESARPLADRLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERPRLNERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDASGNIKIADFGLSNLYHKGKFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKTLVKQISSGAYREPCKPSDACGLIRWLLMVNPIRRATLEDVASHWWVNWGYSTRIGEQEALREGGHPSGDSGRASMADWLRRSSRPLLENGAKVCSFFKQHVPGGGSTGPGLERQHSLKKSRKENDMAQTLQNDPAEDTSSRPGKNSLKLPKGILKKKASPSSGEVQEGPQELRPVSNTPGQPVPAIPLLPRKGILKKSRQRESGYYSSPEPSESGELLDAGDVFVSGDPMEQKSPQASGRLHRKGILKLNGKFSRTALEGTAPSTFGSLDQLASPHPTARASRPSGAVSEDSILSSESFDQLDLPERLPETPLRGCVSVDNLRRLEQPPSEGLKRWWQESLGDSCFSLTDCQEVTAAYRQALGICSKLS", "length": 630 }, "evidence": [ { "id": "A0A8C2N3I1", "url": "https://omabrowser.org/oma/group/A0A8C2N3I1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BZN4-1", "protein_name": "NUAK family SNF1-like kinase 2", "gene_name": "Nuak2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESVALLQRPSQAPSASALASESARPLADGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVGRSRLVTVFENSSKIVIVMEYASRGDLYDYISERPRLSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNLYHKGKFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKTLVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASHWWVNWGYTTGVGEQEALREGGHPSGDFGRASMADWLRRSSRPLLENGAKVCSFFKQHVPGGGSTVPGLERQHSLKKSRKENDMAQNLQGDPAEDTSSRPGKSSLKLPKGILKKKSSTSSGEVQEDPQELRPVPDTPGQPVPAVSLLPRKGILKKSRQRESGYYSSPEPSESGELLDASDVFVSGDPVEQKSPQASGLLLHRKGILKLNGKFSRTALEGTTPSTFGSLDQLASSHPAARPSRPSGAVSEDSILSSESFDQLDLPERLPETPLRGCVSVDNLRGLEQPPSEGLKRWWQESLGDSCFSLTDCQEVTAAYRQALGICSKLS", "length": 639 }, "evidence": [ { "id": "A0A8C2N3I1", "url": "https://omabrowser.org/oma/group/A0A8C2N3I1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H093-1", "protein_name": "NUAK family SNF1-like kinase 2", "gene_name": "NUAK2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESLVFARRSGPTPSAAELARPLAEGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASHWWVNWGYATRVGEQEAPHEGGHPGSDSARASMADWLRRSSRPLLENGAKVCSFFKQHAPGGGSTTPGLERQHSLKKSRKENDMAQSLHSDTADDTAHRPGKSNLKLPKGILKKKVSASAEGVQEDPPELSPIPASPGQAAPLLPKKGILKKPRQRESGYYSSPEPSESGELLDAGDVFVSGDPKEQKPPQASGLLLHRKGILKLNGKFSQTALELAAPTTFGSLDELAPPRPLARASRPSGAVSEDSILSSESFDQLDLPERLPEPPLRGCVSVDNLTGLEEPPSEGPGSCLRRWRQDPLGDSCFSLTDCQEVTATYRQALRVCSKLT", "length": 628 }, "evidence": [ { "id": "A0A8C2N3I1", "url": "https://omabrowser.org/oma/group/A0A8C2N3I1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3I1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ], "pmid": "" }, { "name": "tau-protein kinase activity", "id": "GO:0050321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050321", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3I1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3I1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3I1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3I1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", 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"A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] } ] }, { "uniprot_ac": "A0A8C2M3Y9", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] } ] }, { "uniprot_ac": "A0A8C2M497", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] } ] }, { "uniprot_ac": "A0A8C2QHS8", "gene_name": "Ripk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] } ] }, { "uniprot_ac": "A0A8C2QI80", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] } ] }, { "uniprot_ac": "A0A9J7EXX8", "gene_name": "LOC113832238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] } ] }, { "uniprot_ac": "A0A9J7F0J6", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] } ] }, { "uniprot_ac": "A0A9J7F1D2", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1D2" } ] } ] }, { "uniprot_ac": "A0A9J7F2F1", "gene_name": "Prkcd", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { 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"2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] } ] }, { "uniprot_ac": "A0A9J7F8T0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": 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H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] } ] }, { "uniprot_ac": "A0A9J7G8N4", "gene_name": "Sgk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N4", "database": 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"https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] } ] }, { "uniprot_ac": "A0A9J7GAB0", "gene_name": "Pkn3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] } ] }, { "uniprot_ac": "A0A9J7GAF4", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBI2", "gene_name": "LOC100771767", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": 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"A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] } ] }, { "uniprot_ac": "A0A9J7GJE4", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] } ] }, { "uniprot_ac": "A0A9J7GK55", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] } ] }, { "uniprot_ac": "A0A9J7GLT3", "gene_name": "LOC113838166", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] } ] }, { 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] } ] }, { "uniprot_ac": "A0A9J7GQY0", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] } ] }, { "uniprot_ac": "A0A9J7GR05", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] } ] }, { "uniprot_ac": "A0A9J7GR29", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] } ] }, { "uniprot_ac": "A0A9J7GRB5", "gene_name": "LOC113838167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRB5", "database": 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] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] } ] }, { "uniprot_ac": "A0A9J7GTU0", "gene_name": "LOC100757707", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTU0" } ] } ] }, { "uniprot_ac": "A0A9J7GVC9", "gene_name": "LOC100759146", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVC9" } ] } ] }, { "uniprot_ac": "A0A9J7GX76", "gene_name": "Dapk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GX76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GX76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX76" } ] } ] }, { "uniprot_ac": "A0A9J7GY39", "gene_name": "Akt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A9J7JGG9", "gene_name": "Riok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JGG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGG9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JGG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGG9" } ] } ] }, { "uniprot_ac": "A0A9J7JGQ1", "gene_name": "Trpm6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGQ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGQ1" } ] } ] }, { "uniprot_ac": "A0A9J7JGR2", "gene_name": "Rock1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JGR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A9J7JGR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR2" } ] } ] }, { "uniprot_ac": "A0A9J7JHJ2", "gene_name": "Mast2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JQZ1", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] } ] }, { "uniprot_ac": "A0A9J7JRI3", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N3I2-1", "uniprot_ac": "A0A8C2N3I2", "uniprot_id": "A0A8C2N3I2_CRIGR", "mass": { "chemical_mass": 12691.0, "monoisotopic_mass": 12691.0 }, "refseq": { "ac": "XP_003497274", "name": "vesicle-associated membrane protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497274" }, "gene_names": [ { "name": "Vamp2", "type": "recommended", "evidence": [ { "id": "A0A8C2N3I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I2" } ] }, { "name": "Vamp2", "type": "synonym", 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##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 85 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613643.1) and transcript sequence (IACG01041346.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003497274.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497274" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3I2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Vamp2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I2", "locus": {} } ], "crossref": [ { "id": "cd15870", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15870", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753583", "url": "https://www.ncbi.nlm.nih.gov/gene/100753583", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016444", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016444", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753583", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753583", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N3I2", "url": "https://www.orthodb.org/?gene=A0A8C2N3I2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45701", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45701", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00957", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00957", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003497274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497274", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N3I2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N3I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2X8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2X8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSATAATVPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYFST", "length": 116, "header": "tr|A0A8C2N3I2-1|A0A8C2N3I2_CRIGR Isoform 1 of Vesicle-associated membrane protein 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Vamp2 PE=3 SV=1 CANONICAL=A0A8C2N3I2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N3I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I2/entry#A0A8C2N3I2-1", "sequence": { "sequence": "MSATAATVPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYFST", "length": 116, "header": "tr|A0A8C2N3I2-1|A0A8C2N3I2_CRIGR Isoform 1 of Vesicle-associated membrane protein 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Vamp2 PE=3 SV=1 CANONICAL=A0A8C2N3I2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I2/entry#A0A9J7H2X8-1", "sequence": { "sequence": "MSATAATVPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIAGV", "length": 114, "header": "tr|A0A9J7H2X8-1|A0A9J7H2X8_CRIGR Computationally mapped isoform of Vesicle-associated membrane protein 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Vamp2 PE=3 SV=1 CANONICAL=A0A8C2N3I2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3I2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N3L4-1", "uniprot_ac": "A0A8C2N3L4", "uniprot_id": "A0A8C2N3L4_CRIGR", "mass": { "chemical_mass": 45912.0, "monoisotopic_mass": 45912.0 }, "refseq": { "ac": "XP_003497688", "name": "phakinin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497688" }, "gene_names": [ { "name": "Bfsp2", "type": "recommended", "evidence": [ { "id": "A0A8C2N3L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3L4" } ] }, { "name": "Bfsp2", "type": "synonym", "evidence": [ { "id": "XP_003497688", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497688" } ] } ], "protein_names": [ { "name": "Phakinin", "type": "synonym", "evidence": [ { "id": "A0A8C2N3L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3L4/entry#names_and_taxonomy" } ] }, { "name": "phakinin", "type": "synonym", "evidence": [ { "id": "XP_003497688", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497688" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613657.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003497688.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497688", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497688" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3L4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Bfsp2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3L4", "locus": {} } ], "crossref": [ { "id": "100767821", "url": "https://www.ncbi.nlm.nih.gov/gene/100767821", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767821", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767821", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETIRIQW", "url": "https://omabrowser.org/oma/group/ETIRIQW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N3L4", "url": "https://www.orthodb.org/?gene=A0A8C2N3L4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003497688", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497688", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N3L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3L4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSERRVAADLPPGANSSMPLQRHRVSLRGTRSPSSLESPPASRTSALGSLIRAPGVYVGVAPSGCIGGLSARVTRRALGISSVFLQGLRSSGLTTVPAPGPERDHTAVEDLGSCLVEYMTKVHALEQVSQELETQLRAHLESKAKRSGGWDALRASWASSYQQVGEAVLENARLMLQMETIQAGADDFKERYENEQPFRKAAEEEISSLYKVIDEANLTKTDLEHQIESLKEEMGFLKRSYEEDVKILYKQLAGSELEQTDVPMGTGLDDVLETIRIQWERDVEKNRAEAGALLQAKQQTEVAHVSQTQEEKLAAALSVELHDASCQVQSLQAEMESLRALKRGLENTLHDSKHWHDMELQNLGAVVGRLEAELAEIRSETEQQQQERAHLLACKSQLQKDVASYHALLDREEGN", "length": 415, "header": "tr|A0A8C2N3L4-1|A0A8C2N3L4_CRIGR Isoform 1 of Phakinin OS=Cricetulus griseus OX=10029 GN=Bfsp2 PE=4 SV=1 CANONICAL=A0A8C2N3L4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N3L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3L4/entry#A0A8C2N3L4-1", "sequence": { "sequence": "MSERRVAADLPPGANSSMPLQRHRVSLRGTRSPSSLESPPASRTSALGSLIRAPGVYVGVAPSGCIGGLSARVTRRALGISSVFLQGLRSSGLTTVPAPGPERDHTAVEDLGSCLVEYMTKVHALEQVSQELETQLRAHLESKAKRSGGWDALRASWASSYQQVGEAVLENARLMLQMETIQAGADDFKERYENEQPFRKAAEEEISSLYKVIDEANLTKTDLEHQIESLKEEMGFLKRSYEEDVKILYKQLAGSELEQTDVPMGTGLDDVLETIRIQWERDVEKNRAEAGALLQAKQQTEVAHVSQTQEEKLAAALSVELHDASCQVQSLQAEMESLRALKRGLENTLHDSKHWHDMELQNLGAVVGRLEAELAEIRSETEQQQQERAHLLACKSQLQKDVASYHALLDREEGN", "length": 415, "header": "tr|A0A8C2N3L4-1|A0A8C2N3L4_CRIGR Isoform 1 of Phakinin OS=Cricetulus griseus OX=10029 GN=Bfsp2 PE=4 SV=1 CANONICAL=A0A8C2N3L4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3L4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3L4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767821", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767821", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286YA92-1", "protein_name": "Phakinin isoform X1", "gene_name": "bfsp2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPLPRRRSSFLGQGAAERPGSVGRMSAAATSAPRGVFVGNAPTGGGSSLGTRVSRRALGISSVFLQGLRCSSVPVVAQPGEQGHPFGVDSLNTCLLEYRDKVHALEQLNKQLEEQIRHCLDRKAVSAGTWTGLKQDWEDVYIQVSEAILYNARLMLQTENVQANAEDFKERYENEQPFRKAVEEEINSLYKVIDDANLTRMDLENEIESMKTELINVEQSHMEDVKMLYKQMSGREVDEPDAPTETSLDQILSFIRSHWERVVEKNRAETYAYFECKQAGSLNSKLSQEEEEMECLKTECNDAGCKIQNLQAETESIRALKRGLENALNDAKHWHDIELQNLGSVIGKLEAELTDIRGDIEQQRRDYETLLNNKMKVEMEIGTYHGILDGEESRFYTSTFPAGSSVPEGPTDPTPSTSGQQSCAQTDGSSAPEAPEEKNKF", "length": 441 }, "evidence": [ { "id": "A0A8C2N3L4", "url": "https://omabrowser.org/oma/group/A0A8C2N3L4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZER2-1", "protein_name": "Phakinin", "gene_name": "Bfsp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSERRVAMDLPSGSNASMPLQRHRVSSLRGTRSPSSLDSPPASRTSAVGSLVRAPGVYVGVAPSGGIGGLGARVTRRALGISSVFLQGLRSSGLATAPAPGPERNHATAEDLGGCLVEYMTKVHALEQVSQELETQLRAHLESKAKRSGGWDALRASWASSYQQVGEAVLENARLMLQMETIQAGADDFKERYENEQPFRKAAEEEVSSLYKVIDEANLTKTDLEHQIESLKEELGSLSRSYEEDVKVLYKQLAGSELEQTDVPMGTGLDDVLETIRVQWERDVEKNRAEAGAVLQAKQQTEVVHVSQTQEEKLAAALSVELHDTSRQVQSLQAETESLRALKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELAEIHSETEQQQQERAHLLACKGQLQKDVASYHALLDREESN", "length": 416 }, "evidence": [ { "id": "A0A8C2N3L4", "url": "https://omabrowser.org/oma/group/A0A8C2N3L4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q13515-1", "protein_name": "Phakinin", "gene_name": "BFSP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSERRVVVDLPTSASSSMPLQRRRASFRGPRSSSSLESPPASRTNAMSGLVRAPGVYVGTAPSGCIGGLGARVTRRALGISSVFLQGLRSSGLATVPAPGLERDHGAVEDLGGCLVEYMAKVHALEQVSQELETQLRMHLESKATRSGNWGALRASWASSCQQVGEAVLENARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESLKEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEAGALLQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHALLDREESG", "length": 415 }, "evidence": [ { "id": "A0A8C2N3L4", "url": "https://omabrowser.org/oma/group/A0A8C2N3L4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q28177-1", "protein_name": "Phakinin", "gene_name": "BFSP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSTRRVVVDAPAGASSSMPLQRHKASFRAAQSPSSLDGLPASRTVAVSGLVRTPRVYVGMAPSGPTGGLGARVTRRALGISSVFLQGLRSSGLATAPAPSLERDLGAVEDLGGCLVEYMAKVHALEKVSQELEAQLRMHLESKATRSENWGALRASWASSCQQVGEAVLENARLMLQTENIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANSSKMDLESQIESLKEELGFLSRSYEEDVKMLYKQLAGSELEQLNVPIGTGLDDILETIRIHWERDVEKNRLQAGALLQAKQQAELARRAQTQEEKLAAALRVELHNTSCQIQSLQAETESLRALKRGLENTLHDAKHWHDIELQNLGAVVSRLEAELREMRAEAEQQLQAREHLLSHKCQLQRDVASYHALLDREESS", "length": 415 }, "evidence": [ { "id": "A0A8C2N3L4", "url": "https://omabrowser.org/oma/group/A0A8C2N3L4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6NVD9-1", "protein_name": "Phakinin", "gene_name": "Bfsp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKRRVAADLPSGTNSSMPVQRHRVSSLRGTHSPSSLDSPPASRTSAVGSLVRAPGVYVGVAPSGGIGGLGARVTRRALGISSVFLQGLRSSGLANVPAPGPERDHTTVEDLGGCLVEYMTKVHALEQVSQELETQLRAHLESKAKSSGGWDALRASWASSYQQVGEAVLENARLLLQMETIQAGADDFKERYENEQPFRKAAEEEVSSLYKVIDEANLTKTDLEHQIESLKEELGFLSRSYEEDVKVLYKQLAGSELEQADVPMGTGLDDVLETIRVQWERDVEKNRAEAGALLQAKQQTEVVHVSQTQEEKLAAALSVELHDTSRQVQSLQAETESLRALKRGLENSLHDAQHWHDMELQNLGAVVGRLEAELAEIRSETEQQQQERAHLLACKSQLQKDVASYHALLDREENN", "length": 416 }, "evidence": [ { "id": "A0A8C2N3L4", "url": "https://omabrowser.org/oma/group/A0A8C2N3L4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3L4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3L4" } ], "pmid": "" }, { "name": "intermediate filament", "id": "GO:0005882", "url": 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N3P3-1", "uniprot_ac": "A0A8C2N3P3", "uniprot_id": "A0A8C2N3P3_CRIGR", "mass": { "chemical_mass": 75026.0, "monoisotopic_mass": 75026.0 }, "refseq": { "ac": "XP_027281066", "name": "RING finger protein 145", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281066" }, "gene_names": [ { "name": "Rnf145", "type": "recommended", "evidence": [ { "id": "A0A8C2N3P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3P3" } ] }, { "name": "Rnf145", "type": "synonym", "evidence": [ { "id": "XP_027281066", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281066" } ] } ], "protein_names": [ { "name": "RING finger protein 145", "type": "recommended", "evidence": [ { "id": "A0A8C2N3P3", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027281066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281066" } ] }, { "annotation": "E3 ubiquitin ligase that catalyzes the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. In response to bacterial infection, negatively regulates the phagocyte oxidative burst by controlling the turnover of the NADPH oxidase complex subunits. Promotes monoubiquitination of CYBA and 'Lys-48'-linked polyubiquitination and degradation of CYBB NADPH oxidase catalytic subunits, both essential for the generation of antimicrobial reactive oxygen species. Involved in the maintenance of cholesterol homeostasis. In response to high sterol concentrations ubiquitinates HMGCR, a rate-limiting enzyme in cholesterol biosynthesis, and targets it for degradation. The interaction with INSIG1 is required for this function. In addition, triggers ubiquitination of SCAP, likely inhibiting its transport to the Golgi apparatus and the subsequent processing/maturation of SREBPF2, ultimately down-regulating cholesterol biosynthesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3P3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3P3#function" }, { "database": "UniProtKB", "id": "ARBA00058477", "url": "https://www.uniprot.org/uniprotkb/ARBA00058477#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3P3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3P3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rnf145", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3P3", "locus": {} } ], "crossref": [ { "id": "cd16684", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16684", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762228", "url": "https://www.ncbi.nlm.nih.gov/gene/100762228", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762228", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762228", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N3P3", "url": "https://www.orthodb.org/?gene=A0A8C2N3P3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22763", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22763", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22763:SF167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22763:SF167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13705", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13705", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281066", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N3P3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N3P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3P3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAKEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLSNNPLFQYKYLALNMHYVGYILSVVLLTLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELESAYEGPMYLEPLSLNRFTTALIGQLVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRLLEFLVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPVATKEQLEKHNDICAICYQDMKSAVITPCSHFFHAGCLKKWLYVQDTCPLCHCHLKNSSQLPGLGTEPAPQPPAGAEQNIVLQEGPEPPDHEHPPGTGTQEGSRDSSEHIRRSSASQEGAADPREDLQSAKGETCPVESA", "length": 663, "header": "tr|A0A8C2N3P3-1|A0A8C2N3P3_CRIGR Isoform 1 of RING finger protein 145 OS=Cricetulus griseus OX=10029 GN=Rnf145 PE=4 SV=1 CANONICAL=A0A8C2N3P3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N3P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3P3/entry#A0A8C2N3P3-1", "sequence": { "sequence": "MAAKEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLSNNPLFQYKYLALNMHYVGYILSVVLLTLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELESAYEGPMYLEPLSLNRFTTALIGQLVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRLLEFLVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPVATKEQLEKHNDICAICYQDMKSAVITPCSHFFHAGCLKKWLYVQDTCPLCHCHLKNSSQLPGLGTEPAPQPPAGAEQNIVLQEGPEPPDHEHPPGTGTQEGSRDSSEHIRRSSASQEGAADPREDLQSAKGETCPVESA", "length": 663, "header": "tr|A0A8C2N3P3-1|A0A8C2N3P3_CRIGR Isoform 1 of RING finger protein 145 OS=Cricetulus griseus OX=10029 GN=Rnf145 PE=4 SV=1 CANONICAL=A0A8C2N3P3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3P3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3P3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3P3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3P3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762228", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762228", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3P3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3P3" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3P3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3P3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3P3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3P3" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3P3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3P3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3P3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3P3" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3P3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3P3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 580, "end_pos": 582, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N3P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3P3" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 537, "end_pos": 575, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 455, "end_pos": 457 }, { "start_pos": 580, "end_pos": 582 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N3T0-1", "uniprot_ac": "A0A8C2N3T0", "uniprot_id": "A0A8C2N3T0_CRIGR", "mass": { "chemical_mass": 22199.0, "monoisotopic_mass": 22199.0 }, "refseq": { "ac": "XP_016836137", "name": "density-regulated protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836137" }, "gene_names": [ { "name": "Denr", "type": "recommended", "evidence": [ { "id": "A0A8C2N3T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0" } ] }, { "name": "Denr", "type": "synonym", "evidence": [ { "id": "XP_016836137", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836137" } ] } ], "protein_names": [ { "name": "Density-regulated protein", "type": "recommended", "evidence": [ { "id": "A0A8C2N3T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0/entry#names_and_taxonomy" } ] }, { "name": "density-regulated protein", "type": "synonym", "evidence": [ { "id": "XP_016836137", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836137" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615455.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016836137", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836137" } ] }, { "annotation": "Translation regulator forming a complex with MCTS1 to promote translation reinitiation. Translation reinitiation is the process where the small ribosomal subunit remains attached to the mRNA following termination of translation of a regulatory upstream ORF (uORF), and resume scanning on the same mRNA molecule to initiate translation of a downstream ORF, usually the main ORF (mORF). The MCTS1/DENR complex is pivotal to two linked mechanisms essential for translation reinitiation. Firstly, the dissociation of deacylated tRNAs from post-termination 40S ribosomal complexes during ribosome recycling. Secondly, the recruitment in an EIF2-independent manner of aminoacylated initiator tRNA to P site of 40S ribosomes for a new round of translation. This regulatory mechanism governs the translation of more than 150 genes which translation reinitiation is MCTS1/DENR complex-dependent.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3T0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0#function" }, { "database": "UniProtKB", "id": "ARBA00055205", "url": "https://www.uniprot.org/uniprotkb/ARBA00055205#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3T0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Denr", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0", "locus": {} } ], "crossref": [ { "id": "cd11607", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11607", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765761", "url": "https://www.ncbi.nlm.nih.gov/gene/100765761", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001950", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001950", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046447", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046447", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050318", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050318", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765761", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765761", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EVFEIDM", "url": "https://omabrowser.org/oma/group/EVFEIDM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N3T0", "url": "https://www.orthodb.org/?gene=A0A8C2N3T0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12789", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12789", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12789:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12789:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01253", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01253", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016836137", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836137", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N3T0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N3T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATDVSESSGADCKGDTRNSAKLDSEYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKPETGVSESQGTLGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 198, "header": "tr|A0A8C2N3T0-1|A0A8C2N3T0_CRIGR Isoform 1 of Density-regulated protein OS=Cricetulus griseus OX=10029 GN=Denr PE=3 SV=1 CANONICAL=A0A8C2N3T0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N3T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0/entry#A0A8C2N3T0-1", "sequence": { "sequence": "MATDVSESSGADCKGDTRNSAKLDSEYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKPETGVSESQGTLGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 198, "header": "tr|A0A8C2N3T0-1|A0A8C2N3T0_CRIGR Isoform 1 of Density-regulated protein OS=Cricetulus griseus OX=10029 GN=Denr PE=3 SV=1 CANONICAL=A0A8C2N3T0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3T0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3T0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765761", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765761", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UG52-1", "protein_name": "Density-regulated protein", "gene_name": "DENR", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAADISESGGHDCKGDLKSNTKLDADYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQEAGITEGQGTAGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 198 }, "evidence": [ { "id": "A0A8C2N3T0", "url": "https://omabrowser.org/oma/group/A0A8C2N3T0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZU54-1", "protein_name": "Density-regulated protein", "gene_name": "Denr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATDISESSGADTKNSAKLDADYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQETGISEGQGPVGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 194 }, "evidence": [ { "id": "A0A8C2N3T0", "url": "https://omabrowser.org/oma/group/A0A8C2N3T0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43583-1", "protein_name": "Density-regulated protein", "gene_name": "DENR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAADISESSGADCKGDPRNSAKLDADYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQEAGISEGQGTAGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 198 }, "evidence": [ { "id": "A0A8C2N3T0", "url": "https://omabrowser.org/oma/group/A0A8C2N3T0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P47089-1", "protein_name": "Translation machinery-associated protein 22", "gene_name": "TMA22", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLREVIYCGICSYPPEYCEFSGKLKRCKVWLSENHADLYAKLYGTDDNTQEVEAVTNKLAESSIGEAREEKLEKDLLKIQKKQENREQRELAKKLSSKVIIKREARTKRKFIVAISGLEVFDIDMKKLAKTFASRFATGCSVSKNAEKKEEVVIQGDVMDEVETYIHSLLEEKGLKDVKVETIDAKKKKKPAAEGAAK", "length": 198 }, "evidence": [ { "id": "A0A8C2N3T0", "url": "https://omabrowser.org/oma/group/A0A8C2N3T0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q2HJ47-1", "protein_name": "Density-regulated protein", "gene_name": "DENR", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAADISESGGHDCRGDQRSNTKLDADYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQEAGISEGQGTAGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 198 }, "evidence": [ { "id": "A0A8C2N3T0", "url": "https://omabrowser.org/oma/group/A0A8C2N3T0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54WG0-1", "protein_name": "Density-regulated protein homolog", "gene_name": "denr", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDTESSTPSQPIVVVEYCKICSLPTEYCEYGPSAKQCLKENGPHPNNNKNTASGKDSSNTTATTTTTDTTTTTTTSTENTEEKLKDLKIVDDSKEVSHVDAGKSESKEATGEEKEKEKVSKKKKEVKPQIIIEVNQRNKRKHVTKITGLELYGIKLSDAAKVMAKKFSCGCSVVKSISNPNSEDIDIQGDFGEELVDLIEEKYPTVPLSEIYFLEDKKKVKAR", "length": 224 }, "evidence": [ { "id": "A0A8C2N3T0", "url": "https://omabrowser.org/oma/group/A0A8C2N3T0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5ZJ39-1", "protein_name": "Density-regulated protein", "gene_name": "DENR", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MATDVAEPVVPDCRGDIRSGARSDADYPLRVLYCGVCSLPTEYCEYMPDVTKCRQWLEKNFPDEFAKLTVENSPKQEAGVGEGQGTAGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 198 }, "evidence": [ { "id": "A0A8C2N3T0", "url": "https://omabrowser.org/oma/group/A0A8C2N3T0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9CQJ6-1", "protein_name": "Density-regulated protein", "gene_name": "Denr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATDISESSGADCKGDTKNSAKLDADYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQETGITEGQGPVGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK", "length": 198 }, "evidence": [ { "id": "A0A8C2N3T0", "url": "https://omabrowser.org/oma/group/A0A8C2N3T0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "translation reinitiation", "id": "GO:0002188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002188", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3T0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0" } ], "pmid": "" }, { "name": "ribosome disassembly", "id": "GO:0032790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032790", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3T0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0" } ], "pmid": "" }, { "name": "IRES-dependent viral translational initiation", "id": "GO:0075522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075522", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3T0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0" } ], "pmid": "" }, { "name": "formation of translation preinitiation complex", "id": "GO:0001731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001731", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3T0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3T0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3T0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3T0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N3T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3T0" }, { "id": "PS50296", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50296" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUI1", "eco_id": "ECO_0000259", "start_pos": 115, "end_pos": 182, "start_aa": "Val", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N3U7-1", "uniprot_ac": "A0A8C2N3U7", "uniprot_id": "A0A8C2N3U7_CRIGR", "mass": { "chemical_mass": 24378.0, "monoisotopic_mass": 24378.0 }, "refseq": { "ac": "XP_007646069", "name": "beta-crystallin B3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646069" }, "gene_names": [ { "name": "Crybb3", "type": "recommended", "evidence": [ { "id": "A0A8C2N3U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U7" } ] }, { "name": "Crybb3", "type": "synonym", "evidence": [ { "id": "XP_007646069", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646069" } ] } ], "protein_names": [ { "name": "Beta-crystallin B3", "type": "recommended", "evidence": [ { "id": "A0A8C2N3U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U7/entry#names_and_taxonomy" } ] }, { "name": "Beta-B3 crystallin", "type": "synonym", "evidence": [ { "id": "A0A8C2N3U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U7/entry#names_and_taxonomy" } ] }, { "name": "beta-crystallin B3", "type": "synonym", "evidence": [ { "id": "XP_007646069", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646069" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614356.1) annotated using gene prediction method: Gnomon. 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"https://www.uniprot.org/uniprotkb/A0A8C2N3W2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKSRTKRFKRPQFSPTGSCQAAVAAAANGTEDDEDDGPAAELLEKLQHPSAEVRECACAGLARLVQQRPALPDLARRDAVRRLGPLLLDSSLAVRETAAGALRNLSACGGFEVCDDMVAKDIMTPLVALLRECSTGLDSNEMSPQEKADKNRNSIESIANEAVNVLWNVCECSSRAVSIFNKEGCLEIVLKYLHTFPTSIDLAVSAAYCLQTVTEDNPELLKYFDGTALRVLESALLCPVTSMEYILLKTLVAGTIWNLKDIIPSKSQAEIINAILKILSEVLEMNAADTVIQMKEAETQRLKTASETEDVIANANGDDLVEDDEMEEIPRKKKLRRKTFISDLLPSTDKELRETMALLTAQQTALEVIVNMCCSEDPSDDEWEELSSSDESEAFMENSFNECSGQLLSPLCLSHEIHTALTNFLIPKKVFEKTSSPNSMAIDICSRNPTWKPLIKKLNTIQCRALMCLQSLVSLLDMDHLGGAPALQTLAQHLSQLLFSQPDFAKHADFLEAISSALRALLQAMAAKNIPQCMTPEQLMTLCKAGIHSSSIGVRVNVVSILGITGSVLAKEDGTLETLKTIGCFLLEVATKDPSLVVTGEALDALFDVFADGEEAEKASVQIKLLSTLKEFQPVFKMKIRKEGRGKYSPDQLCVLDNVKMNLRRFVAYQEAVEKRLTS", "length": 680, "header": "tr|A0A8C2N3W2-1|A0A8C2N3W2_CRIGR Isoform 1 of HEAT repeat-containing protein 3 OS=Cricetulus griseus OX=10029 GN=Heatr3 PE=3 SV=1 CANONICAL=A0A8C2N3W2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N3W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3W2/entry#A0A8C2N3W2-1", "sequence": { "sequence": "MGKSRTKRFKRPQFSPTGSCQAAVAAAANGTEDDEDDGPAAELLEKLQHPSAEVRECACAGLARLVQQRPALPDLARRDAVRRLGPLLLDSSLAVRETAAGALRNLSACGGFEVCDDMVAKDIMTPLVALLRECSTGLDSNEMSPQEKADKNRNSIESIANEAVNVLWNVCECSSRAVSIFNKEGCLEIVLKYLHTFPTSIDLAVSAAYCLQTVTEDNPELLKYFDGTALRVLESALLCPVTSMEYILLKTLVAGTIWNLKDIIPSKSQAEIINAILKILSEVLEMNAADTVIQMKEAETQRLKTASETEDVIANANGDDLVEDDEMEEIPRKKKLRRKTFISDLLPSTDKELRETMALLTAQQTALEVIVNMCCSEDPSDDEWEELSSSDESEAFMENSFNECSGQLLSPLCLSHEIHTALTNFLIPKKVFEKTSSPNSMAIDICSRNPTWKPLIKKLNTIQCRALMCLQSLVSLLDMDHLGGAPALQTLAQHLSQLLFSQPDFAKHADFLEAISSALRALLQAMAAKNIPQCMTPEQLMTLCKAGIHSSSIGVRVNVVSILGITGSVLAKEDGTLETLKTIGCFLLEVATKDPSLVVTGEALDALFDVFADGEEAEKASVQIKLLSTLKEFQPVFKMKIRKEGRGKYSPDQLCVLDNVKMNLRRFVAYQEAVEKRLTS", "length": 680, "header": "tr|A0A8C2N3W2-1|A0A8C2N3W2_CRIGR Isoform 1 of HEAT repeat-containing protein 3 OS=Cricetulus griseus OX=10029 GN=Heatr3 PE=3 SV=1 CANONICAL=A0A8C2N3W2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"id": "A0A8C2N3W2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3W2" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3W2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3W2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3W2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3W2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N3W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3W2" }, { "id": "PF25567", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25567" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SYO1-like TPR repeats", "eco_id": "ECO_0000259", "start_pos": 417, "end_pos": 673, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 29, "end_pos": 31 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027251650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251650" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pdlim5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8", "locus": {} } ], "crossref": [ { "id": "cd06753", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06753", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09453", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09453", "database": "CDD", 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"A0A9J7KDR6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KER2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KER2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KER2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KER2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNYTVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQAHVRIGDVVLSIDGISAQGMTHLEAQNKIKGCTGSLNMTLQRASTAAKPEPVAVQKGEPKEVVKPVPITSPAVSKVSSTTNMAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASPSPVAAVTPPPFSASGLHANTNLSTDQCSSAPNTGKSAVNVPRQPTVTSVCSEPAQELAEGQRRGSQGDIKQQNGPPRKHIVERNTEFYHIPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESENDNTKKANSSEEPSQQSASPLSKSEGQESPGSSRPGVAGLRTAAAFKPAGSTSAIKSPSWQRPSHAAPSTGRITNSATSSGTRVPANSAVGAPQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICRGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "length": 592, "header": "tr|A0A8C2N3Z8-1|A0A8C2N3Z8_CRIGR Isoform 1 of PDZ and LIM domain protein 5 isoform X4 OS=Cricetulus griseus OX=10029 GN=Pdlim5 PE=4 SV=1 CANONICAL=A0A8C2N3Z8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N3Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8/entry#A0A8C2N3Z8-1", "sequence": { "sequence": "MSNYTVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQAHVRIGDVVLSIDGISAQGMTHLEAQNKIKGCTGSLNMTLQRASTAAKPEPVAVQKGEPKEVVKPVPITSPAVSKVSSTTNMAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASPSPVAAVTPPPFSASGLHANTNLSTDQCSSAPNTGKSAVNVPRQPTVTSVCSEPAQELAEGQRRGSQGDIKQQNGPPRKHIVERNTEFYHIPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESENDNTKKANSSEEPSQQSASPLSKSEGQESPGSSRPGVAGLRTAAAFKPAGSTSAIKSPSWQRPSHAAPSTGRITNSATSSGTRVPANSAVGAPQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICRGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "length": 592, "header": "tr|A0A8C2N3Z8-1|A0A8C2N3Z8_CRIGR Isoform 1 of PDZ and LIM domain protein 5 isoform X4 OS=Cricetulus griseus OX=10029 GN=Pdlim5 PE=4 SV=1 CANONICAL=A0A8C2N3Z8-1" }, "locus": {} }, { "isoform_ac": "A0A8C2QQ84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8/entry#A0A8C2QQ84-1", "sequence": { "sequence": "MSNYTVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQAHVRIGDVVLSIDGISAQGMTHLEAQNKIKGCTGSLNMTLQRASTAAKPEPVAVQKGEPKEVVKPVPITSPAVSKVSSTTNMAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASPSPVAAVTPPPFSASGLHANTNLSTDQCSSAPNTGKSAVNVPRQPTVTSVCSEPAQELAEGQRRGSQGDIKQQNGPPRKHIVERNTEFYHIPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESENDNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ", "length": 337, "header": "tr|A0A8C2QQ84-1|A0A8C2N3Z8_CRIGR Computationally mapped isoform of PDZ and LIM domain protein 5 isoform X4 OS=Cricetulus griseus OX=10029 GN=Pdlim5 PE=4 SV=1 CANONICAL=A0A8C2N3Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F8R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8/entry#A0A9J7F8R7-1", "sequence": { "sequence": "MSNYTVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQAHVRIGDVVLSIDGISAQGMTHLEAQNKIKGCTGSLNMTLQRASTAAKPEPVAVQKPTVTSVCSEPAQELAEGQRRGSQGDIKQQNGPPRKHIVERNTEFYHIPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESENDNTKKANSSEEPSQQSASPLSKSEGQESPGSSRPGVAGLRTAAAFKPAGSTSAIKSPSWQRPSHAAPSTGRITNSATSSGTRVPANSAVGAPQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICRGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "length": 483, "header": "tr|A0A9J7F8R7-1|A0A8C2N3Z8_CRIGR Computationally mapped isoform of PDZ and LIM domain protein 5 isoform X4 OS=Cricetulus griseus OX=10029 GN=Pdlim5 PE=4 SV=1 CANONICAL=A0A8C2N3Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K3M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8/entry#A0A9J7K3M4-1", "sequence": { "sequence": "MSNYTVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQAHVRIGDVVLSIDGISAQGMTHLEAQNKIKGCTGSLNMTLQRASTAAKPEPVAVQKGEPKEVVKPVPITSPAVSKVSSTTNMAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASPSPVAAVTPPPFSASGLHANTNLSTDQCSSAPNTGKSAVNVPRQPTVTSVCSEPAQELAEGQRRGSQGDIKQQNGPPRKHIVERNTEFYHIPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESENDNTKKANSEEPSQQSASPLSKSEGQESPGSSRPGVAGLRTAAAFKPAGSTSAIKSPSWQRPSHAAPSTGRITNSATSSGTRVPANSAVGAPQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICRGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "length": 591, "header": "tr|A0A9J7K3M4-1|A0A8C2N3Z8_CRIGR Computationally mapped isoform of PDZ and LIM domain protein 5 isoform X4 OS=Cricetulus griseus OX=10029 GN=Pdlim5 PE=4 SV=1 CANONICAL=A0A8C2N3Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KDR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8/entry#A0A9J7KDR6-1", "sequence": { "sequence": "MSNYTVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQAHVRIGDVVLSIDGISAQGMTHLEAQNKIKGCTGSLNMTLQRASTAAKPEPVAVQKPTVTSVCSEPAQELAEGQRRGSQGDIKQQNGPPRKHIVERNTEFYHIPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESENDNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ", "length": 228, "header": "tr|A0A9J7KDR6-1|A0A8C2N3Z8_CRIGR Computationally mapped isoform of PDZ and LIM domain protein 5 isoform X4 OS=Cricetulus griseus OX=10029 GN=Pdlim5 PE=4 SV=1 CANONICAL=A0A8C2N3Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KER2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8/entry#A0A9J7KER2-1", "sequence": { "sequence": "MAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASPSPVAAVTPPPFSASGLHANTNLSTDQCSSAPNTGKSAVNVPRQPTVTSVCSEPAQELAEGQRRGSQGDIKQQNGPPRKHIVERNTEFYHIPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESENDNTKKANSSEEPSQQSASPLSKSEGQESPGSSRPGVAGLRTAAAFKPAGSTSAIKSPSWQRPSHAAPSTGRITNSATSSGTRVPANSAVGAPQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICRGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "length": 470, "header": "tr|A0A9J7KER2-1|A0A8C2N3Z8_CRIGR Computationally mapped isoform of PDZ and LIM domain protein 5 isoform X4 OS=Cricetulus griseus OX=10029 GN=Pdlim5 PE=4 SV=1 CANONICAL=A0A8C2N3Z8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 170, "start_aa": "Thr", "end_pos": 170, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr170", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QQ84", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QQ84" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QQ84", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QQ84" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770600", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770600", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "muscle alpha-actinin binding", "id": "GO:0051371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051371", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8" } ], "pmid": "" }, { "name": "filamentous actin", "id": "GO:0031941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031941", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8" } ], "pmid": "" }, { "name": "muscle structure development", "id": "GO:0061061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061061", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N3Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 414, "end_pos": 472, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3Z8" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 85, "start_aa": "Gly", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 170 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N410-1", "uniprot_ac": "A0A8C2N410", "uniprot_id": "A0A8C2N410_CRIGR", "mass": { "chemical_mass": 62258.0, "monoisotopic_mass": 62258.0 }, "refseq": { "ac": "XP_035297320", "name": "liver carboxylesterase isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297320" }, "gene_names": [ { "name": "LOC100766249", "type": "recommended", "evidence": [ { "id": "A0A8C2N410", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N410" } ] }, { "name": "LOC100766249", "type": "synonym", "evidence": [ { "id": "XP_035297320", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297320" } ] } ], "protein_names": [ { "name": "Carboxylic ester hydrolase", "type": "recommended", "evidence": [ { "id": "A0A8C2N410", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N410/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.-", "type": "synonym", "evidence": [ { "id": "A0A8C2N410", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N410/entry#names_and_taxonomy" } ] }, { "name": "liver carboxylesterase isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035297320", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297320" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035297320", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297320" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N410", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N410" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100766249", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N410", "locus": {} } ], "crossref": [ { "id": "cd00312", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00312", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766249", "url": "https://www.ncbi.nlm.nih.gov/gene/100766249", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "INEYGYQ", "url": "https://omabrowser.org/oma/group/INEYGYQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N410", "url": "https://www.orthodb.org/?gene=A0A8C2N410", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11559", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11559", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00135", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00135", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035297320", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297320", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N410", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N410", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N410-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N410-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLDRFPAWLNTVSCGLLLFLLHVHGQDSVSPIRNTHTGQVRGSLVYVKDGELGVYTFLGIPFAKPPVGPLRFAPPEPSEPWSGVRNGTSEPAMCPQTDMMTSQVSKERKMIVPPISMSEDCLYLNIYTPAHAHEGSNLPVMVWIHGGALVAGMASMNDGSILAATEDIVIVSIQYRLGILGFFSTGDKHARGNWGYLDQVAALHWVQQNIASFGGNPGQVTIFGASAGGTSVSSLVVSPMSKGLFHRAIMQSGVALLPDLISEKSEVVYTVMTNLSGCEAKDSEALVHCLREKTEAEILAINQVFTMIPAVVDGTFLPRHPRELLASVDFHPVPSIIGIDSDECGWGIPLYMGLDHVIKNITRETLPAFLKSRAAHMMLPPECSDLLMEEYMGDVEDPQTLQAQFRELMEDFMFVIPALQVAHFQRSHAPVYFYEFQHQPSFIKHKDVRPSHVRADHGDHGAFVFGSDFWGLKLDLTEEEKLLNRRMMKYWANFARHGNPNSEGLPYWPELVHDDQYLKLDIQPAVGRALKARKLQFWTKILPQKIQDIKGAQDKHAEL", "length": 560, "header": "tr|A0A8C2N410-1|A0A8C2N410_CRIGR Isoform 1 of Carboxylic ester hydrolase OS=Cricetulus griseus OX=10029 GN=LOC100766249 PE=3 SV=1 CANONICAL=A0A8C2N410-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N410-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N410/entry#A0A8C2N410-1", "sequence": { "sequence": "MPLDRFPAWLNTVSCGLLLFLLHVHGQDSVSPIRNTHTGQVRGSLVYVKDGELGVYTFLGIPFAKPPVGPLRFAPPEPSEPWSGVRNGTSEPAMCPQTDMMTSQVSKERKMIVPPISMSEDCLYLNIYTPAHAHEGSNLPVMVWIHGGALVAGMASMNDGSILAATEDIVIVSIQYRLGILGFFSTGDKHARGNWGYLDQVAALHWVQQNIASFGGNPGQVTIFGASAGGTSVSSLVVSPMSKGLFHRAIMQSGVALLPDLISEKSEVVYTVMTNLSGCEAKDSEALVHCLREKTEAEILAINQVFTMIPAVVDGTFLPRHPRELLASVDFHPVPSIIGIDSDECGWGIPLYMGLDHVIKNITRETLPAFLKSRAAHMMLPPECSDLLMEEYMGDVEDPQTLQAQFRELMEDFMFVIPALQVAHFQRSHAPVYFYEFQHQPSFIKHKDVRPSHVRADHGDHGAFVFGSDFWGLKLDLTEEEKLLNRRMMKYWANFARHGNPNSEGLPYWPELVHDDQYLKLDIQPAVGRALKARKLQFWTKILPQKIQDIKGAQDKHAEL", "length": 560, "header": "tr|A0A8C2N410-1|A0A8C2N410_CRIGR Isoform 1 of Carboxylic ester hydrolase OS=Cricetulus griseus OX=10029 GN=LOC100766249 PE=3 SV=1 CANONICAL=A0A8C2N410-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N410", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N410" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N410", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N410" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "O70631-1", "protein_name": "Acylcarnitine hydrolase", "gene_name": "Ces2c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARKQPHSWLNAVLFGLLLILIHVWGQDSPESSSIRTTHTGQVRGKLDHVRDTKAGVHTFLGIPFAKAPVGPLRFAPPEDPEPWSGVRDGTSHPAMCLQNIDMLDEVGLTDMKMILSSIPMSEDCLYLNIYTPAHAHEGSNLPVMVCIHGGALVIGMASMCDGSLLAVNEDLVVVAIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGVSAGGTSVSSHVISPMSQGLFHGAIMESGVALLPDLISETSETVSTTVAKLSGCEATDSETLVRCLRAKSGAEILVINKVFKMIPAVVDGEFLPRHPKELLASEDFHPVPSIIGVNTDEYCCTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLPPECGDLLMEEYMGNTDDPQTLQIQYAEMMGDFLFVIPALQVAHFQRSHAPVYFYEFQHAPSYFKNVRPPHVKADHADEVPFVFGSFFWGIKVDFTEEEKLLSRRMMKYWANFARHGNPNSEGLPYWPVLDHDEQYLQLDTQPAVDRALKARRLQFWTKTLPQKIQELNGAQKNHAEL", "length": 561 }, "evidence": [ { "id": "A0A8C2N410", "url": "https://omabrowser.org/oma/group/A0A8C2N410/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N410", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N410" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N410", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N410" }, { "id": "PF00135", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00135" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Carboxylesterase type B", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 539, "start_aa": "Ser", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 275, "end_pos": 277 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415" } ] }, { "name": "Arid3c", "type": "synonym", "evidence": [ { "id": "XP_027259117", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259117" } ] } ], "protein_names": [ { "name": "AT-rich interactive domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "A0A8C2N415", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415/entry#names_and_taxonomy" } ] }, { "name": "ARID domain-containing protein", "type": "synonym", "evidence": [ { "id": "A0A8C2N415", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415/entry#names_and_taxonomy" } ] }, { "name": "AT-rich interactive domain-containing protein 3C isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027259117", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259117" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027259117", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259117" } ] }, { "annotation": "Transcription factor involved in monocyte-to-macrophage differentiation. Forms a complex with NPM1 to translocate to the nucleus, acting as a transcription factor that promotes the expression of the genes involved in macrophage differentiation, such as STAT3, STAT1 and JUNB.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K395", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K395#function" }, { "database": "UniProtKB", "id": "ARBA00058617", "url": "https://www.uniprot.org/uniprotkb/ARBA00058617#function" }, { "database": "UniProtKB", "id": "A0A8C2N415", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415#function" }, { "database": "UniProtKB", "id": "A0A8C2N598", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N598#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N415", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Arid3c", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415", "locus": {} } ], "crossref": [ { "id": "cd16880", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16880", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753126", "url": "https://www.ncbi.nlm.nih.gov/gene/100753126", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023334", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023334", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753126", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753126", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N415", "url": "https://www.orthodb.org/?gene=A0A8C2N415", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15348", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15348", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15348:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15348:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027259117", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259117", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N415", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N415-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N598", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N598", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N598-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N598-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K395", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K395", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K395-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K395-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEALQRQQAARLAQGVGPLAPPRLPLPQPPLLGARTLQAEGALGVVRAEEEEDVEEDEEGEAPLAEQEAAEESHPGARCPNSPSNQPPGLQPHEWTYEEQFKQLYELDADPKRKEFLDDLFSFMQKRGTPVNRVPIMAKQVLDLYALFRLVTAKGGLVEVINRKVWREVTRGLSLPTTITSAAFTLRTQYMKYLYPYECETRALSSPGELQAAIDSNRREGRRQAYTTVPLFSLAGPTPRGAPGPASGHGPSPASTPSCPGPAQGSASGLPVHACAQLSPGPVKKEETGVPPPRLALPVGLALEAAREKLAPEEPPEKRAVLMGSMDPPRLGAPPSFLPRGKVPLREERLDGPLNLAGSGISSINMALEINGVVYTGILFARRQPVPASLGPTNPPPPSTGPPSSTLP", "length": 408, "header": "tr|A0A8C2N415-1|A0A8C2N415_CRIGR Isoform 1 of AT-rich interactive domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=Arid3c PE=4 SV=1 CANONICAL=A0A8C2N415-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N415-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415/entry#A0A8C2N415-1", "sequence": { "sequence": 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"MEALQRQQAARLAQGVGPLAPPRLPLPQPPLLGARTLQAEGALGVVRAEEEEDVEEDEEGEAPLAEQEAAEESHPGARCPNSPSNQPPGLQPHEWTYEEQFKQLYELDADPKRKEFLDDLFSFMQKRGTPVNRVPIMAKQVLDLYALFRLVTAKGGLVEVINRKVWREVTRGLSLPTTITSAAFTLRTQYMKYLYPYECETRALSSPGELQAAIDSNRREGRRQAYTTVPLFSLAGPTPRGAPGPASGHGPSPASTPSCPGPAQGSASGLPVHACAQLSPGPVKKEETGVPPPRLALPVGLALEAAREKLAPEEPPEKRAVLMGSMDPPRLGAPPSFLPRGKVPLRGILFARRQPVPASLGPTNPPPPSTGPPSSTLP", "length": 378, "header": "tr|A0A8C2N598-1|A0A8C2N598_CRIGR Computationally mapped isoform of AT-rich interactive domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=Arid3c PE=4 SV=1 CANONICAL=A0A8C2N415-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K395-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415/entry#A0A9J7K395-1", "sequence": { "sequence": "MEALQRQQAARLAQGVGPLAPPRLPLPQPPLLGARTLQAEGALGVVRAEEEEDVEEDEEGEAPLAEQEAAEESHPGARCPNSPSNQPPGLQPHEWTYEEQFKQLYELDADPKRKEFLDDLFSFMQKRGTPVNRVPIMAKQVLDLYALFRLVTAKGGLVEVINRKVWREVTRGLSLPTTITSAAFTLRTQYMKYLYPYECETRALSSPGELQAAIDSNRREGRRQAYTTVPLFSLAGPTPRGAPGPASGHGPSPASTPSCPGPAQGSASGLPVHACAQLSPGPVKKEERLDGPLNLAGSGISSINMALEINGVVYTGILFARRQPVPASLGPTNPPPPSTGPPSSTLP", "length": 347, "header": "tr|A0A9J7K395-1|A0A8C2N415_CRIGR Computationally mapped isoform of AT-rich interactive domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=Arid3c PE=4 SV=1 CANONICAL=A0A8C2N415-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 238, "start_aa": "Thr", "end_pos": 238, "end_aa": "Thr", "residue": "Thr", 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K395", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K395" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K395", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K395" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753126", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753126", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N415", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N415", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N415", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N415", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N415", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N415", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N415", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415" } ], "pmid": "" }, { "name": "macrophage differentiation", "id": "GO:0030225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030225", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N415", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N415", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N415" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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"uniprot_canonical_ac": "A0A8C2N427-1", "uniprot_ac": "A0A8C2N427", "uniprot_id": "A0A8C2N427_CRIGR", "mass": { "chemical_mass": 17911.0, "monoisotopic_mass": 17911.0 }, "refseq": { "ac": "XP_003510106", "name": "vesicle transport protein SFT2A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510106" }, "gene_names": [ { "name": "Sft2d1", "type": "recommended", "evidence": [ { "id": "A0A8C2N427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N427" } ] }, { "name": "Sft2d1", "type": "synonym", "evidence": [ { "id": "XP_003510106", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510106" } ] } ], "protein_names": [ { "name": "Vesicle transport protein", "type": "recommended", "evidence": [ { "id": "A0A8C2N427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N427/entry#names_and_taxonomy" } ] }, { "name": "vesicle transport protein SFT2A", "type": "synonym", "evidence": [ { "id": "XP_003510106", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510106" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614821.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510106", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510106" } ] }, { "annotation": "May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N427", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N427#function" }, { "database": "UniProtKB", "id": "RU363111", "url": "https://www.uniprot.org/uniprotkb/RU363111#function" }, { "database": "UniProtKB", "id": "ARBA00003566", "url": "https://www.uniprot.org/uniprotkb/ARBA00003566#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N427", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N427" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sft2d1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N427", "locus": {} } ], "crossref": [ { "id": "100754831", "url": "https://www.ncbi.nlm.nih.gov/gene/100754831", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754831", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754831", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IAAIVWK", "url": "https://omabrowser.org/oma/group/IAAIVWK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N427", "url": "https://www.orthodb.org/?gene=A0A8C2N427", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23137", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23137", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23137:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23137:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510106", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510106", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N427", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N427", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N427-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N427-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKLRRVLSGQDDEEQGLTAQVLDASSLSFNTRLKWFIICFVAGVFCSILGTGLLWLPNGIKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFETTRLLATVIMLLCFVFTLCAALWWRKKGLALLFCILQFLSMTWYSLSYIPYARDAVLKCCSSLFS", "length": 159, "header": "tr|A0A8C2N427-1|A0A8C2N427_CRIGR Isoform 1 of Vesicle transport protein OS=Cricetulus griseus OX=10029 GN=Sft2d1 PE=3 SV=1 CANONICAL=A0A8C2N427-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N427-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N427/entry#A0A8C2N427-1", "sequence": { "sequence": "MEKLRRVLSGQDDEEQGLTAQVLDASSLSFNTRLKWFIICFVAGVFCSILGTGLLWLPNGIKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFETTRLLATVIMLLCFVFTLCAALWWRKKGLALLFCILQFLSMTWYSLSYIPYARDAVLKCCSSLFS", "length": 159, "header": "tr|A0A8C2N427-1|A0A8C2N427_CRIGR Isoform 1 of Vesicle transport protein OS=Cricetulus griseus OX=10029 GN=Sft2d1 PE=3 SV=1 CANONICAL=A0A8C2N427-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N427", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N427" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N427", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N427" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754831", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754831", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XTJ6-1", "protein_name": "Vesicle transport protein", "gene_name": "SFT2D1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "LSSSGAEITLGKWEAKLPLSAIHCLVLDASTLSFGTRVKWFAICFIAGVACSILGTALLWLPKGIKLFAVFYTLGNIAALASTCFLMGPLKQLKTMFEPKRLIATVVMLLFLVLTLCAVFWWNKKGLALIFCILQFLAMTWYSLSYIPYARDAVIKCFTSCLE", "length": 163 }, "evidence": [ { "id": "A0A8C2N427", "url": "https://omabrowser.org/oma/group/A0A8C2N427/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SBY3-1", "protein_name": "Vesicle transport protein", "gene_name": "SFT2D1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEKLRRVLSGQDDEEQGLTAQVLDASTLSFNTRLKWFVICFVSGIFFSFLGTGLLWLPGGIKLFAVFYTFGNIAALASTCFLMGPVKQLKKMFETTRLLATIVMILCLVLTLCAALWWRKKGLALLFCILQFLSLTWYSLSYIPYARDAVIKCCSSLLS", "length": 159 }, "evidence": [ { "id": "A0A8C2N427", "url": "https://omabrowser.org/oma/group/A0A8C2N427/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6RFZ0-1", "protein_name": "Vesicle transport protein", "gene_name": "SFT2D1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRTPLGRPPGAEPARRKLETGTSGQPEESRLPGFLRGRERGGPGGAAAAMEKLRRVLSGQDDEEQGLTAQVLDASTLSFNTRLKWFAICFVSGIFFSILGTGLLWLPGGIKLFAVFYTFGNIAALASTCFLMGPVKQLKKMFETTRLLATVIMLLCFVLTLCAALWWHKKGLAVLFCILQFLSMTWYSLSYIPYARDAVIKCCSSLLS", "length": 208 }, "evidence": [ { "id": "A0A8C2N427", "url": "https://omabrowser.org/oma/group/A0A8C2N427/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5SSN7-1", "protein_name": "Vesicle transport protein SFT2A", "gene_name": "Sft2d1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKLRRVLSGQDDEEQGLTAQVLDASSLSFNTRLKWFVICFVAGIFFSFLGTGLLWLPNGMKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFETTRLLATIIMLLCLVFTLCAALWWRKKGLALLFCILQFLSMTWYSLSYIPYARDAVLKCCSSLLG", "length": 159 }, "evidence": [ { "id": "A0A8C2N427", "url": "https://omabrowser.org/oma/group/A0A8C2N427/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WV19-1", "protein_name": "Vesicle transport protein SFT2A", "gene_name": "SFT2D1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKLRRVLSGQDDEEQGLTAQVLDASSLSFNTRLKWFAICFVCGVFFSILGTGLLWLPGGIKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFEATRLLATIVMLLCFIFTLCAALWWHKKGLAVLFCILQFLSMTWYSLSYIPYARDAVIKCCSSLLS", "length": 159 }, "evidence": [ { "id": "A0A8C2N427", "url": "https://omabrowser.org/oma/group/A0A8C2N427/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9LT07-1", "protein_name": "Vesicle transport protein", "gene_name": "MQM1.18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKMNQAIEKMKMLVGMEVEDEQQAADEESSLSFMEDLNRNCALTTKQRFYGFAICLSAGLTCTLLSMLVFFNPVKFGITFTLGNLMALGSTAFLIGPQRQVTMMLDPARIYATALYLASIIIALFCALYVRNKLLTLLAIILEFTGLIWYSLSYIPFARTMVSKIFMTCFDTEF", "length": 175 }, "evidence": [ { "id": "A0A8C2N427", "url": "https://omabrowser.org/oma/group/A0A8C2N427/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VPD4-1", "protein_name": "Vesicle transport protein", "gene_name": "Dmel\\CG5104", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDKLRRVLSGDEPTPEEESSIITQINDMSTLSWSTRIKGFVICFALGILLSLLGSVALFLHRGIVVFAVFYTLGNVISMASTCFLMGPFKQIKKMFAETRLIATIIVLVMMVLTFIAAIVWKKAGLTLIFIIIQSLAMTWYSLSYIPYARDAVKKTMSAILEV", "length": 163 }, "evidence": [ { "id": "A0A8C2N427", "url": "https://omabrowser.org/oma/group/A0A8C2N427/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N427", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N427" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N427", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N427" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N427", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N427" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N427", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N427" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N427", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N427" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N468-1", "uniprot_ac": "A0A8C2N468", "uniprot_id": "A0A8C2N468_CRIGR", "mass": { "chemical_mass": 31376.0, "monoisotopic_mass": 31376.0 }, "refseq": { "ac": "XP_035303920", "name": "intercellular adhesion molecule 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303920" }, "gene_names": [ { "name": "Icam2", "type": "recommended", "evidence": [ { "id": "A0A8C2N468", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N468" } ] }, { "name": "Icam2", "type": "synonym", "evidence": [ { "id": "XP_035303920", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303920" } ] } ], "protein_names": [ { "name": "Intercellular adhesion molecule 2", "type": "synonym", "evidence": [ { "id": "A0A8C2N468", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N468/entry#names_and_taxonomy" } ] }, { "name": "intercellular adhesion molecule 2", "type": "synonym", "evidence": [ { "id": "XP_035303920", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303920" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303920", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303920" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N468", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N468" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Icam2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N468", "locus": {} } ], "crossref": [ { "id": "100750973", "url": "https://www.ncbi.nlm.nih.gov/gene/100750973", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750973", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750973", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QVYEPVQ", "url": "https://omabrowser.org/oma/group/QVYEPVQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N468", "url": "https://www.orthodb.org/?gene=A0A8C2N468", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13771", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13771", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13771:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13771:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303920", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303920", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N468", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N468", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N468-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N468-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSFACRSLPITLLALLCCLGSGEKAFEVYIWSEKHVVEAWESWKVNCSTSCDNPKVGGLETTMSKMMLEEHPQGKWKQFLVSNASHDMKLICHFTCAEQQRSEDLNITVFQPPAQVTLRLQPPRVIVGETFTIECTTLAVKPLESLTLTLLRGRETLQNQTFEGTELEATVRFNSTALTKDDLNFSCQAELDLRPHGGYIIRSISESQILEVFEPIQDNQMVIIIVVVSLLLFLFVTSVLLCFILGQHWHRRRTGTYGVLAAWRRLPRAFRQRAM", "length": 276, "header": "tr|A0A8C2N468-1|A0A8C2N468_CRIGR Isoform 1 of Intercellular adhesion molecule 2 OS=Cricetulus griseus OX=10029 GN=Icam2 PE=3 SV=1 CANONICAL=A0A8C2N468-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N468-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N468/entry#A0A8C2N468-1", "sequence": { "sequence": "MPSFACRSLPITLLALLCCLGSGEKAFEVYIWSEKHVVEAWESWKVNCSTSCDNPKVGGLETTMSKMMLEEHPQGKWKQFLVSNASHDMKLICHFTCAEQQRSEDLNITVFQPPAQVTLRLQPPRVIVGETFTIECTTLAVKPLESLTLTLLRGRETLQNQTFEGTELEATVRFNSTALTKDDLNFSCQAELDLRPHGGYIIRSISESQILEVFEPIQDNQMVIIIVVVSLLLFLFVTSVLLCFILGQHWHRRRTGTYGVLAAWRRLPRAFRQRAM", "length": 276, "header": "tr|A0A8C2N468-1|A0A8C2N468_CRIGR Isoform 1 of Intercellular adhesion molecule 2 OS=Cricetulus griseus OX=10029 GN=Icam2 PE=3 SV=1 CANONICAL=A0A8C2N468-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N468", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N468" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"MSSFACWNLSLTLLVLFCSPGSGEKAFEVYIRSEKQIVKATEAWRVNCSTSCAAPEIGGLETPTNKLMLEEDPHGKWIEFLVSNATVDTVLLCHFTCSGKQQAESFNIRVYEPPAQVTLKLQPPRVFMGEAFTIECKVPSVKPLESLTLSLLCGRETLKNQTFGGAETVPEEVIAIFNSTALKKDGLNFSCQAELDLRPHGGSLYRRISEYQSLEVYEIRQDNQMVIIIVVVSILLFLFVTSVLLCFILGQHWHRRRTGTYGVLAAWRRLPRALRGR", "length": 277 }, "evidence": [ { "id": "A0A8C2N468", "url": "https://omabrowser.org/oma/group/A0A8C2N468/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N468", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N468" } ], "pmid": "" }, { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N468", "url": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N480-1", "uniprot_ac": "A0A8C2N480", "uniprot_id": "A0A8C2N480_CRIGR", "mass": { "chemical_mass": 32574.0, "monoisotopic_mass": 32574.0 }, "refseq": { "ac": "XP_027280989", "name": "endoplasmic reticulum-Golgi intermediate compartment protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280989" }, "gene_names": [ { "name": "Ergic1", "type": "recommended", "evidence": [ { "id": "A0A8C2N480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480" } ] }, { "name": 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Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027280989.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280989" } ] }, { "annotation": "Plays a role in transport between endoplasmic reticulum and Golgi.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JUC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUC3#function" }, { "database": "UniProtKB", "id": "RU369013", "url": "https://www.uniprot.org/uniprotkb/RU369013#function" }, { "database": "UniProtKB", "id": "A0A8C2N480", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N480", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ergic1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480", "locus": {} } ], "crossref": [ { "id": "100774570", "url": "https://www.ncbi.nlm.nih.gov/gene/100774570", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045888", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045888", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774570", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774570", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N480", "url": "https://www.orthodb.org/?gene=A0A8C2N480", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10984", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10984", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10984:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10984:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07970", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07970", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13850", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13850", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280989", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N480", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N480-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUC3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFDFRRFDIYRKVPKDLTQPTYTGAIISICCCLFILFLFLSELTGFITTEVVNELYVDDPDKDSGGKIDVSLNISLPNLHCELVGLDIQDEMGRHEVGHIDNSMKIPLNNGAGCRFEGQFSINKVPGNFHVSTHSATAQPQNPDMTHIIHKLSFGDTLQVQNVHGAFNALGGADRLTSNPLASHDYILKIVPTVYEDKSGKQRYSYQYTVANKEYVAYSHTGRIIPAIWFRYDLSPITVKYTERRQPLYRFITTICAIIGGTFTVAGILDSCIFTASEAWKKIQLGKIH", "length": 290, "header": "tr|A0A8C2N480-1|A0A8C2N480_CRIGR Isoform 1 of Endoplasmic reticulum-Golgi intermediate compartment protein OS=Cricetulus griseus OX=10029 GN=Ergic1 PE=3 SV=1 CANONICAL=A0A8C2N480-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N480-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480/entry#A0A8C2N480-1", "sequence": { "sequence": "MPFDFRRFDIYRKVPKDLTQPTYTGAIISICCCLFILFLFLSELTGFITTEVVNELYVDDPDKDSGGKIDVSLNISLPNLHCELVGLDIQDEMGRHEVGHIDNSMKIPLNNGAGCRFEGQFSINKVPGNFHVSTHSATAQPQNPDMTHIIHKLSFGDTLQVQNVHGAFNALGGADRLTSNPLASHDYILKIVPTVYEDKSGKQRYSYQYTVANKEYVAYSHTGRIIPAIWFRYDLSPITVKYTERRQPLYRFITTICAIIGGTFTVAGILDSCIFTASEAWKKIQLGKIH", "length": 290, "header": "tr|A0A8C2N480-1|A0A8C2N480_CRIGR Isoform 1 of Endoplasmic reticulum-Golgi intermediate compartment protein OS=Cricetulus griseus OX=10029 GN=Ergic1 PE=3 SV=1 CANONICAL=A0A8C2N480-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JUC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480/entry#A0A9J7JUC3-1", "sequence": { "sequence": "MASTLLRFDIYRKVPKDLTQPTYTGAIISICCCLFILFLFLSELTGFITTEVVNELYVDDPDKDSGGKIDVSLNISLPNLHCELVGLDIQDEMGRHEVGHIDNSMKIPLNNGAGCRFEGQFSINKVPGNFHVSTHSATAQPQNPDMTHIIHKLSFGDTLQVQNVHGAFNALGGADRLTSNPLASHDYILKIVPTVYEDKSGKQRYSYQYTVANKEYVAYSHTGRIIPAIWFRYDLSPITVKYTERRQPLYRFITTICAIIGGTFTVAGILDSCIFTASEAWKKIQLGKIH", "length": 290, "header": "tr|A0A9J7JUC3-1|A0A8C2N480_CRIGR Computationally mapped isoform of Endoplasmic reticulum-Golgi intermediate compartment protein OS=Cricetulus griseus OX=10029 GN=Ergic1 PE=3 SV=1 CANONICAL=A0A8C2N480-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JUC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUC3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JUC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUC3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774570", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774570", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N480", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N480", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N480", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N480", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment membrane", "id": "GO:0033116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033116", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N480", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N480", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N480", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480" }, { "id": "PF07970", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07970" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endoplasmic reticulum vesicle transporter C-terminal", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 271, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2N480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N480" }, { "id": "PF13850", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endoplasmic reticulum vesicle transporter N-terminal", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 97, "start_aa": "Phe", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N481-1", "uniprot_ac": "A0A8C2N481", "uniprot_id": "A0A8C2N481_CRIGR", "mass": { "chemical_mass": 35853.0, "monoisotopic_mass": 35853.0 }, "refseq": { "ac": "XP_035294865", "name": "phospholipid phosphatase-related protein type 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294865" }, "gene_names": [ { "name": "Plppr1", "type": "recommended", "evidence": [ { "id": "A0A8C2N481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N481" } ] }, { "name": "Plppr1", "type": "synonym", "evidence": [ { "id": "XP_035294865", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294865" } ] } ], "protein_names": [ { "name": "Phospholipid phosphatase-related protein type 1", "type": "recommended", "evidence": [ { "id": "A0A8C2N481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N481/entry#names_and_taxonomy" } ] }, { "name": "Inactive 2-lysophosphatidate phosphatase PLPPR1", "type": "synonym", "evidence": [ { "id": "A0A8C2N481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N481/entry#names_and_taxonomy" } ] }, { "name": "Lipid phosphate phosphatase-related protein type 1", "type": "synonym", "evidence": [ { "id": "A0A8C2N481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N481/entry#names_and_taxonomy" } ] }, { "name": "Plasticity-related gene 3 protein", "type": "synonym", "evidence": [ { "id": "A0A8C2N481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N481/entry#names_and_taxonomy" } ] }, { "name": "phospholipid phosphatase-related protein type 1", "type": "synonym", "evidence": [ { "id": "XP_035294865", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294865" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035294865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294865" } ] }, { "annotation": "May play a role in neurite outgrowth and neurogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N481", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N481#function" }, { "database": "UniProtKB", "id": "ARBA00029385", "url": "https://www.uniprot.org/uniprotkb/ARBA00029385#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N481", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N481" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Plppr1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N481", "locus": {} } ], "crossref": [ { "id": "cd03384", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03384", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756834", "url": "https://www.ncbi.nlm.nih.gov/gene/100756834", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756834", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756834", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CRAHHEF", "url": "https://omabrowser.org/oma/group/CRAHHEF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N481", "url": "https://www.orthodb.org/?gene=A0A8C2N481", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10165", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10165", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10165:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10165:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035294865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294865", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N481", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N481", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N481-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N481-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVGNNTQRSYSIIPCFIFVELVIMAGTVLLAYYFECTDTFQVHIQGFFCQDGDLMKPYPGTEEESFITPLVLYCVLAATPTAIIFIGEISMYFIKSTRESLIAEEKTILTGECCYLNPLLRRIIRFIGVFAFGLFATDIFVNAGQVVTGHLTPYFLTVCQPNYTSTDCRAHHQFITNGNICTGDLEVIEQARRSFPSKHAALSIYSALYATMYITSTIKTKSSRLAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLGMCVVHNFKGTQGSPSKPKPEDPRGVPLMAFPRIESPLETLSAQNHSASMTEVT", "length": 325, "header": "tr|A0A8C2N481-1|A0A8C2N481_CRIGR Isoform 1 of Phospholipid phosphatase-related protein type 1 OS=Cricetulus griseus OX=10029 GN=Plppr1 PE=3 SV=1 CANONICAL=A0A8C2N481-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N481-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N481/entry#A0A8C2N481-1", "sequence": { "sequence": "MAVGNNTQRSYSIIPCFIFVELVIMAGTVLLAYYFECTDTFQVHIQGFFCQDGDLMKPYPGTEEESFITPLVLYCVLAATPTAIIFIGEISMYFIKSTRESLIAEEKTILTGECCYLNPLLRRIIRFIGVFAFGLFATDIFVNAGQVVTGHLTPYFLTVCQPNYTSTDCRAHHQFITNGNICTGDLEVIEQARRSFPSKHAALSIYSALYATMYITSTIKTKSSRLAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLGMCVVHNFKGTQGSPSKPKPEDPRGVPLMAFPRIESPLETLSAQNHSASMTEVT", "length": 325, "header": "tr|A0A8C2N481-1|A0A8C2N481_CRIGR Isoform 1 of Phospholipid phosphatase-related protein type 1 OS=Cricetulus griseus OX=10029 GN=Plppr1 PE=3 SV=1 CANONICAL=A0A8C2N481-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N481", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N481" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N481", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N481" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756834", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756834", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BJF3-1", "protein_name": "Phospholipid phosphatase-related protein type 1", "gene_name": "PLPPR1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027256934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256934" } ] }, { "annotation": "Mediates the uptake of pyruvate into mitochondria.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N499", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N499#function" }, { "database": "UniProtKB", "id": "RU363100", "url": "https://www.uniprot.org/uniprotkb/RU363100#function" }, { "database": "UniProtKB", "id": "A0A8C2N5L4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5L4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5L4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5L4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mpc1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5L4", "locus": {} } ], "crossref": [ { "id": "100756279", "url": "https://www.ncbi.nlm.nih.gov/gene/100756279", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756279", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756279", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FLQHFWG", "url": "https://omabrowser.org/oma/group/FLQHFWG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N499", "url": "https://www.orthodb.org/?gene=A0A8C2N499", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N5L4", "url": "https://www.orthodb.org/?gene=A0A8C2N5L4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14154", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14154", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03650", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03650", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027256934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256934", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "64720", "url": "https://www.rhea-db.org/rhea/64720", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N499", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N499", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N499-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N499-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N5L4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N5L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5L4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGALVRKAADYVRSKDFRDYLMSTHFWGPVANWGLPIAAINDMKKSPEIISGRMTFALCCYSLTFMRFAYKVQPRNWLLFACHVTNEVAQLIQGGRLINYEMSKKASS", "length": 109, "header": "tr|A0A8C2N5L4-1|A0A8C2N5L4_CRIGR Isoform 1 of Mitochondrial pyruvate carrier OS=Cricetulus griseus OX=10029 GN=Mpc1 PE=3 SV=1 CANONICAL=A0A8C2N5L4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N499-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5L4/entry#A0A8C2N499-1", "sequence": { "sequence": "MHFWGPVANWGLPIAAINDMKKSPEIISGRMTFALCCYSLTFMRFAYKVQPRNWLLFACHVTNEVAQLIQGGRLINYEMSKKASS", "length": 85, "header": "tr|A0A8C2N499-1|A0A8C2N5L4_CRIGR Computationally mapped isoform of Mitochondrial pyruvate carrier OS=Cricetulus griseus OX=10029 GN=Mpc1 PE=3 SV=1 CANONICAL=A0A8C2N5L4-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N5L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5L4/entry#A0A8C2N5L4-1", "sequence": { "sequence": "MAGALVRKAADYVRSKDFRDYLMSTHFWGPVANWGLPIAAINDMKKSPEIISGRMTFALCCYSLTFMRFAYKVQPRNWLLFACHVTNEVAQLIQGGRLINYEMSKKASS", "length": 109, "header": "tr|A0A8C2N5L4-1|A0A8C2N5L4_CRIGR Isoform 1 of Mitochondrial pyruvate carrier OS=Cricetulus griseus OX=10029 GN=Mpc1 PE=3 SV=1 CANONICAL=A0A8C2N5L4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"uniprot_canonical_ac": "Q949R9-1", "protein_name": "Mitochondrial pyruvate carrier 1", "gene_name": "MPC1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATSRFQAFLNSPIGPKTTHFWGPIANWGFVAAGLVDMQKPPEMISGNMSSAMCVYSALFMRFAWMVQPRNYLLLACHASNETVQLYQLSRWARAQGYLSSKKEEEKPSQ", "length": 110 }, "evidence": [ { "id": "A0A8C2N5L4", "url": "https://omabrowser.org/oma/group/A0A8C2N5L4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5L4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5L4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "pyruvate import into mitochondria", "id": "GO:0006850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006850", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5L4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5L4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "64720", "name": "", "equation": "pyruvate(out) + H(+)(out) = pyruvate(in) + H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "64720", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64720" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N583-1", "uniprot_ac": "A0A8C2N583", "uniprot_id": "A0A8C2N583_CRIGR", "mass": { "chemical_mass": 62949.0, "monoisotopic_mass": 62949.0 }, "refseq": { "ac": "XP_003494984", "name": "6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003494984" }, "gene_names": [ { "name": "Pfkfb3", "type": "recommended", "evidence": [ { "id": "A0A8C2N583", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N583" } ] }, { "name": "Pfkfb3", "type": "synonym", "evidence": [ { "id": "XP_003494984", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003494984" } ] } ], "protein_names": [ { "name": "6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003494984", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003494984" }, { "id": "A0A8C2N583", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N583/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613580.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003494984", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003494984" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N583", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N583" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pfkfb3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N583", "locus": {} } ], "crossref": [ { "id": "cd07067", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07067", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762756", "url": "https://www.ncbi.nlm.nih.gov/gene/100762756", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762756", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762756", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RCLMGYF", "url": "https://omabrowser.org/oma/group/RCLMGYF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N4A2", "url": "https://www.orthodb.org/?gene=A0A8C2N4A2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N583", "url": "https://www.orthodb.org/?gene=A0A8C2N583", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JI71", "url": "https://www.orthodb.org/?gene=A0A9J7JI71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10606", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10606", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10606:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10606:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00300", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00300", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01591", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01591", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003494984", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003494984", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N4A2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N4A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N583", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N583", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N583-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N583-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JI71", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JI71-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLELTQSRVQKIWVPVDHRPSLPRTCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMRVRKQCALAALRDVKSYLTKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRINCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEYNLQGKIGGDSGLSSRGKKFANALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVSTHRERSDAVKIQHFASVVRPSSYTELDFLSVESAKQDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQNMKSPRSGTESSQKH", "length": 549, "header": "tr|A0A8C2N583-1|A0A8C2N583_CRIGR Isoform 1 of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pfkfb3 PE=3 SV=1 CANONICAL=A0A8C2N583-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N4A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N583/entry#A0A8C2N4A2-1", "sequence": { "sequence": "MPLELTQSRVQKIWVPVDHRPSLPRTCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMRVRKQCALAALRDVKSYLTKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRINCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEYNLQGKIGGDSGLSSRGKKFANALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVSTHRERSDNMKSPRSGTESSQKH", "length": 462, "header": "tr|A0A8C2N4A2-1|A0A8C2N583_CRIGR Computationally mapped isoform of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pfkfb3 PE=3 SV=1 CANONICAL=A0A8C2N583-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N583-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N583/entry#A0A8C2N583-1", "sequence": { "sequence": "MPLELTQSRVQKIWVPVDHRPSLPRTCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMRVRKQCALAALRDVKSYLTKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRINCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEYNLQGKIGGDSGLSSRGKKFANALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVSTHRERSDAVKIQHFASVVRPSSYTELDFLSVESAKQDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQNMKSPRSGTESSQKH", "length": 549, "header": "tr|A0A8C2N583-1|A0A8C2N583_CRIGR Isoform 1 of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pfkfb3 PE=3 SV=1 CANONICAL=A0A8C2N583-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JI71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N583/entry#A0A9J7JI71-1", "sequence": { "sequence": "MPFRKACGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMRVRKQCALAALRDVKSYLTKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRINCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEYNLQGKIGGDSGLSSRGKKFANALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVSTHRERSDAVKIQHFASVVRPSSYTELDFLSVESAKQDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQNMKSPRSGTESSQKH", "length": 529, "header": "tr|A0A9J7JI71-1|A0A8C2N583_CRIGR Computationally mapped isoform of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pfkfb3 PE=3 SV=1 CANONICAL=A0A8C2N583-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI71", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI71" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI71", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI71" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762756", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762756", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2AUP5-1", "protein_name": "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3", "gene_name": "Pfkfb3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMRVRKQCALAALRDVKSYLTKEGGQIAVFDATNTTRERRHMILNFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRINCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEYNLQGKIGGDSGLSSRGKKFANALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVSTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFEERVASTSAALPSCLPPEVPTQLPGQPLLGKACLT", "length": 514 }, "evidence": [ { "id": "A0A8C2N583", "url": "https://omabrowser.org/oma/group/A0A8C2N583/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O35552-1", "protein_name": "6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3", "gene_name": "Pfkfb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMRVRKQCALAALRDVKSYLTKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRINCYEASYQPLDPDKCDRDLSFIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEYNVQGKIGGDSGLSSRGKKFANALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVSTHRERSEAVKIQHFASVVRPSSYTELDFLSVESAKQDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQPLLGKACLRTVCHIFSKFSPY", "length": 555 }, "evidence": [ { "id": "A0A8C2N583", "url": "https://omabrowser.org/oma/group/A0A8C2N583/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q16875-1", "protein_name": "6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3", "gene_name": "PFKFB3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH", "length": 520 }, "evidence": [ { "id": "A0A8C2N583", "url": "https://omabrowser.org/oma/group/A0A8C2N583/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "fructose-2,6-bisphosphate 2-phosphatase activity", "id": "GO:0004331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004331", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N583", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N583" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N583", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N583" } ], "pmid": "" }, { "name": "6-phosphofructo-2-kinase activity", "id": "GO:0003873", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003873", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N583", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N583" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N583", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N583" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fructose metabolic process", "id": "GO:0006000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006000", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N583", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N583" } ], "pmid": "" }, { "name": "fructose 2,6-bisphosphate metabolic process", "id": "GO:0006003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006003", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N583", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N583" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N583", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N583" }, { "id": "PF01591", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01591" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "6-phosphofructo-2-kinase", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 246, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N4B1-1", "uniprot_ac": "A0A8C2N4B1", "uniprot_id": "A0A8C2N4B1_CRIGR", "mass": { "chemical_mass": 143925.0, "monoisotopic_mass": 143925.0 }, "refseq": { "ac": "XP_003497654", "name": "VWFA and cache domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497654" }, "gene_names": [ { "name": "Cachd1", "type": "recommended", "evidence": [ { "id": "A0A8C2N4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B1" } ] }, { "name": "Cachd1", "type": "synonym", "evidence": [ { "id": "XP_003497654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497654" } ] } ], "protein_names": [ { "name": "VWFA and cache domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8C2N4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B1/entry#names_and_taxonomy" } ] }, { "name": "VWFA and cache domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003497654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497654" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 178 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613655.1) and transcript sequence (IACG01040459.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003497654.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497654", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497654" } ] }, { "annotation": "May regulate voltage-dependent calcium channels.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B1#function" }, { "database": "UniProtKB", "id": "ARBA00053598", "url": "https://www.uniprot.org/uniprotkb/ARBA00053598#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cachd1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B1", "locus": {} } ], "crossref": [ { "id": "100756408", "url": "https://www.ncbi.nlm.nih.gov/gene/100756408", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756408", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756408", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N4B1", "url": "https://www.orthodb.org/?gene=A0A8C2N4B1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10166:SF68", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10166:SF68", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003497654", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497654", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N4B1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N4B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAREPKEEETVRPTALVRRCPRCPGWPGAPRPPLWLLCLVACWILGAVADADVSILDEAQVLASQMRRLAAEELGVVTMQRIFNSLVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTVSCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQLQIAKDAAQVILRAIDEHDKISVLTVADAVRTCSLDQCYKTYLSPATSETKRKMSTFVSSVKPSDSPTQHAVGFHRAFQLIRSTSNNTRFQANTDMVIIYLSAGITSKDSSEEDKKATLRVINEENGFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGIPDRTALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSRIITVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLVDPKGHAPLEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRSYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCNQRLESGDCFGVLDCEWCVVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVMERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFYHYRSHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1288, "header": "tr|A0A8C2N4B1-1|A0A8C2N4B1_CRIGR Isoform 1 of VWFA and cache domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Cachd1 PE=3 SV=1 CANONICAL=A0A8C2N4B1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N4B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B1/entry#A0A8C2N4B1-1", "sequence": { "sequence": "MAREPKEEETVRPTALVRRCPRCPGWPGAPRPPLWLLCLVACWILGAVADADVSILDEAQVLASQMRRLAAEELGVVTMQRIFNSLVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTVSCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQLQIAKDAAQVILRAIDEHDKISVLTVADAVRTCSLDQCYKTYLSPATSETKRKMSTFVSSVKPSDSPTQHAVGFHRAFQLIRSTSNNTRFQANTDMVIIYLSAGITSKDSSEEDKKATLRVINEENGFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGIPDRTALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSRIITVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLVDPKGHAPLEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRSYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCNQRLESGDCFGVLDCEWCVVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVMERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFYHYRSHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1288, "header": "tr|A0A8C2N4B1-1|A0A8C2N4B1_CRIGR Isoform 1 of VWFA and cache domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Cachd1 PE=3 SV=1 CANONICAL=A0A8C2N4B1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756408", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756408", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "voltage-gated calcium channel activity", "id": "GO:0005245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "voltage-gated calcium channel complex", "id": "GO:0005891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005891", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 919, "end_pos": 921, "annotation": "n_glycosylation_sequon" }, { "start_pos": 954, "end_pos": 956, "annotation": "n_glycosylation_sequon" }, { "start_pos": 999, "end_pos": 1001, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B1" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 242, "end_pos": 457, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 387, "end_pos": 389 }, { "start_pos": 582, "end_pos": 584 }, { "start_pos": 601, "end_pos": 603 }, { "start_pos": 919, "end_pos": 921 }, { "start_pos": 954, "end_pos": 956 }, { "start_pos": 999, "end_pos": 1001 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N4B2-1", "uniprot_ac": "A0A8C2N4B2", "uniprot_id": "A0A8C2N4B2_CRIGR", "mass": { "chemical_mass": 58200.0, "monoisotopic_mass": 58200.0 }, "refseq": { "ac": "XP_007612784", "name": "dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007612784" }, "gene_names": [ { "name": "Alg6", "type": "recommended", "evidence": [ { "id": "A0A8C2N4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B2" } ] }, { "name": "Alg6", "type": "synonym", "evidence": [ { "id": "XP_007612784", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007612784" } ] } ], "protein_names": [ { "name": "Alpha-1,3-glucosyltransferase", "type": "recommended", "evidence": [ { "id": "A0A8C2N4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B2/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "A0A8C2N4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B2/entry#names_and_taxonomy" } ] }, { "name": "dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "type": "synonym", "evidence": [ { "id": "XP_007612784", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007612784" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613655.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007612784", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007612784" } ] }, { "annotation": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the first glucose residue from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide intermediate Man(9)GlcNAc(2)-PP-Dol to produce Glc(1)Man(9)GlcNAc(2)-PP-Dol. Glc(1)Man(9)GlcNAc(2)-PP-Dol is a substrate for ALG8, the following enzyme in the biosynthetic pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B2#function" }, { "database": "UniProtKB", "id": "ARBA00044720", "url": "https://www.uniprot.org/uniprotkb/ARBA00044720#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Alg6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B2", "locus": {} } ], "crossref": [ { "id": "100753783", "url": "https://www.ncbi.nlm.nih.gov/gene/100753783", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753783", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753783", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FQVPPMH", "url": "https://omabrowser.org/oma/group/FQVPPMH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N4B2", "url": "https://www.orthodb.org/?gene=A0A8C2N4B2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12413", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12413", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12413:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12413:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03155", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03155", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007612784", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007612784", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "30635", "url": "https://www.rhea-db.org/rhea/30635", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N4B2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N4B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENWYWMTLVVLIGLTVRWTVSLNPYSGAGKPPMFGDYEAQRHWQEITFNLPVKDWYFNSSDNNLQYWGLDYPPLTAYHSLLCAYVAEFINPDWVALHTSRGYESQAHKLFMRTTVLVADLFIYIPAVLLYCYSLKEISPKRKMAVALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGVSYDWDLLGSLAFCLALNYKQMELYHSLPFFCFLLGKCFKKGLKGKGFVLLMKIACTVLASFLLCWLPFFTEREHALQVLRRLFPVDRGLFEDKVANIWCSVNVFLKIKEILPRHIQLAISFCLTFLSLLPACIKLTLQPSSKGFRFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLNEIPFMSTWFLLVSTFSMLPLLLKDELLMPSVVTVMAFLVVCVTSFPLCESTSEEQLQLTPFAVSVRRRLPGFTFLPRIIQYLFLSSVITMVLLTILSVTLNPPQKLPDLFSVLVCSVSCINFIFFLVYFNIVIVWDSKNGRNRKKIK", "length": 507, "header": "tr|A0A8C2N4B2-1|A0A8C2N4B2_CRIGR Isoform 1 of Alpha-1,3-glucosyltransferase OS=Cricetulus griseus OX=10029 GN=Alg6 PE=3 SV=1 CANONICAL=A0A8C2N4B2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N4B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B2/entry#A0A8C2N4B2-1", "sequence": { "sequence": "MENWYWMTLVVLIGLTVRWTVSLNPYSGAGKPPMFGDYEAQRHWQEITFNLPVKDWYFNSSDNNLQYWGLDYPPLTAYHSLLCAYVAEFINPDWVALHTSRGYESQAHKLFMRTTVLVADLFIYIPAVLLYCYSLKEISPKRKMAVALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGVSYDWDLLGSLAFCLALNYKQMELYHSLPFFCFLLGKCFKKGLKGKGFVLLMKIACTVLASFLLCWLPFFTEREHALQVLRRLFPVDRGLFEDKVANIWCSVNVFLKIKEILPRHIQLAISFCLTFLSLLPACIKLTLQPSSKGFRFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLNEIPFMSTWFLLVSTFSMLPLLLKDELLMPSVVTVMAFLVVCVTSFPLCESTSEEQLQLTPFAVSVRRRLPGFTFLPRIIQYLFLSSVITMVLLTILSVTLNPPQKLPDLFSVLVCSVSCINFIFFLVYFNIVIVWDSKNGRNRKKIK", "length": 507, "header": "tr|A0A8C2N4B2-1|A0A8C2N4B2_CRIGR Isoform 1 of Alpha-1,3-glucosyltransferase OS=Cricetulus griseus OX=10029 GN=Alg6 PE=3 SV=1 CANONICAL=A0A8C2N4B2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753783", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753783", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D1M5U4-1", "protein_name": "Alpha-1,3-glucosyltransferase", "gene_name": "ALG6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEKWYLMTVVVLIGLTVRWTVSLNSYSGAGKPPMFGDYEAQRHWQEITFNLPINQWYFNSSDNNLQYWGLDYPPLTAYHSLLCAYVAKFINPDWIALHTSRGYESQAHKLFMRATVLIADLLIYIPAVVLYCCCLKEISTKKKIANALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGVSYDWDLLGSLAFCLAINYKQMELYHSLPFFCFLLGKCFKKGLKGKGFVLLIKLACTVVASFILCWLPFFTEREQTLQVLRRLFPVDRGLFEDKVANVWCSFSVFLKIKDILPHHIQIMISFCFTFLSLLPACMKLTLHPSPKGFKFTLVSCALSFFLFSFQVHEKSILLVSVPVCLVLSEIPFMSTWFLLVSTFSMLPLLLKDELVMPSVVTAMAFFIACTTSFSIFEKTSEEELQLKSFSISVRKYFPCFTFLPRIIRYLFLTSVITMVLLTLMTVTLDPPQKLPDLFSVLVCFVSCLNFLFFLVYFNIIIMWDSKNERNQKKIN", "length": 507 }, "evidence": [ { "id": "A0A8C2N4B2", "url": "https://omabrowser.org/oma/group/A0A8C2N4B2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6QF86-1", "protein_name": "Alpha-1,3-glucosyltransferase", "gene_name": "ALG6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEKWYLMTAAVLLGLTVRWTVSLNSYSGAGKPPMFGDYEAQRHWQEITFNLPIKQWYFNSSDNNLQYWGLDYPPLTAYHSFLCAYVAKFINPDWIALHSSRGYESQAHKLFMRATVLIADLLIYIPAVVLYCCCLKEISTKKKIATALCILLYPGLILIDYGHFQYNSVSLGFALWGILGVSYDWDLLGSLAFCLAINYKQMELYHSLPFFCFLLGKCFKKGLKGKGLVLLIKLACTVVASFILCWLPFFTEREQTLQVLRRLFPVDRGLFEDKVANIWCSFSVFFKIRDILPHHIQIMISFCFTFLSLLPACIKLTLHPSPKGFRFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLSEIPFMSTWFLLVSTFSMLPLLLKDELLMPSVVTVMAFFIACATSFSIFEKTSEEELQLKCFSTSVRKYFTCFTFLPRIIQHLFLMSVITMILLTTMTVTLDPPQKLPDLFAVLVCFVSCLHFLFFLVYFTIIIMWDSKTGRSQKKIS", "length": 507 }, "evidence": [ { "id": "A0A8C2N4B2", "url": "https://omabrowser.org/oma/group/A0A8C2N4B2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q12001-1", "protein_name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "gene_name": "ALG6", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAIGKRLLVNKPAEESFYASPMYDFLYPFRPVGNQWLPEYIIFVCAVILRCTIGLGPYSGKGSPPLYGDFEAQRHWMEITQHLPLSKWYWYDLQYWGLDYPPLTAFHSYLLGLIGSFFNPSWFALEKSRGFESPDNGLKTYMRSTVIISDILFYFPAVIYFTKWLGRYRNQSPIGQSIAASAILFQPSLMLIDHGHFQYNSVMLGLTAYAINNLLDEYYAMAAVCFVLSICFKQMALYYAPIFFAYLLSRSLLFPKFNIARLTVIAFATLATFAIIFAPLYFLGGGLKNIHQCIHRIFPFARGIFEDKVANFWCVTNVFVKYKERFTIQQLQLYSLIATVIGFLPAMIMTLLHPKKHLLPYVLIACSMSFFLFSFQVHEKTILIPLLPITLLYSSTDWNVLSLVSWINNVALFTLWPLLKKDGLHLQYAVSFLLSNWLIGNFSFITPRFLPKSLTPGPSISSINSDYRRRSLLPYNVVWKSFIIGTYIAMGFYHFLDQFVAPPSKYPDLWVLLNCAVGFICFSIFWLWSYYKIFTSGSKSMKDL", "length": 544 }, "evidence": [ { "id": "A0A8C2N4B2", "url": "https://omabrowser.org/oma/group/A0A8C2N4B2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3T1L5-1", "protein_name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "gene_name": "Alg6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESWTWMTVVVLLGLTVRWTVSLNSYSGAGKPPMFGDYEAQRHWQEITLNLPVKQWYFNSSDNNLQYWGLDYPPLTAYHSLLCAYVAKFINPDWVALHTSRGYESQAHKLFMRTTVLAADLLIYIPAVLLYCYSLKEISPKRKIASALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGVSCDWDLLGSLAFCLALNYKQMELYHSLPFFCFLLGKCFKKGLRGKGSALFIRIACTVVASFLLCWLPFLTEREHALQVVRRLFPVDRGLFEDKVANIWCSLNVFLKIKDILPRHIQIAISFCFTFLSLLPACIKLTVQPSAKGFRFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLTEIPFMSTWFLLVSTFSMLPLLLKDQLLLPSVVTVMAFLIACSTFFPMFENTSEEQLQLKSFAVSVRRHLPGFTFLPRIIQCLFLSSVITMILLTILSVTLDPPQKLPDLFSVLICFVSCVNFVFFLVYFNIVIMWDSKNGRNRKKID", "length": 507 }, "evidence": [ { "id": "A0A8C2N4B2", "url": "https://omabrowser.org/oma/group/A0A8C2N4B2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3TAE8-1", "protein_name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "gene_name": "Alg6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWPWMAVVVLLGLTVRWTVSLSSYSGAGKPPMFGDYEAQRHWQEITLNLPVKQWYFNSSDNNLLYWGLDYPPLTAYHSLLCAYVAKFINPDWVALHTSRGYESQAHKLFMRATVLAADLLIYVPAVLLYCYSLKEISPKRKIASALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGVSWDWDLLGSLAFCLALNYKQMELYHSLPFFCFLLGKCFKKGLKGKGLALFIRIACTVLASFLLCWLPFLTEREHALQVVRRLFPVDRGLFEDKVANIWCSVNVFLKIKDTLPRHIQIAISFCFTLLSLLPACIKLTVRPSCKGFRFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLTEIPFMSTWFLLVSTFSMLPLLLKDELLLPSVVTVMAFVIACGTFFPMLENTSEEQLQLKSFAVSVRRHLPGFTFLPRIMQCLFLSSVITMVLLTILSVTLDPPQKLPDLFPVLICFVSCVNFVFFLVYFNIVIMWDSKNGRNRKKIE", "length": 507 }, "evidence": [ { "id": "A0A8C2N4B2", "url": "https://omabrowser.org/oma/group/A0A8C2N4B2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54QG6-1", "protein_name": "Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "gene_name": "alg6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSLNNKVGFSSLNISIVLLILMISLLARYLVSLNGYSGQSKPPMFGDYEAQRHWMEITTNLDIHQWYFNSTDNDLMYWGLDYPPLTAYLSWVFGKIGEFIEPKSMELFTSRGYETDSGKLFMRMTVIVSDLFIWLPSVWFFVKTFYKQRNISQQISAFLFISLQPGLLLIDHGHFQYNGVSLGLGLFAITFIIRDQQLLASFFFVLSLNYKQMCLYYSPAFFFYLLLSNFEFTLKFSKIFSSIFKILKIGIVVIFTFILCWIPFLSIEQASQVLFRLFPFARGLYEDKVANFWCFISIIINVKNLFTTDQLIKICLILTLVTMLPLVYGIKRIPKNKFVFIHSLINSSFSFFLFSFQVHEKTILLVSLPISLLILHHPNMVWWFILISTFSMFPLLFKDGLVIPYFAIMILYIVIGYQFKNSITRSNNQFKHQNSQENLLASSDKSFYSIYLNYWFYLNIIGMVVCHLLYQFAPHPPHLPSLWLLLVCNFSFIHFILTFFYFIKEMTTFSPIKIKSN", "length": 518 }, "evidence": [ { "id": "A0A8C2N4B2", "url": "https://omabrowser.org/oma/group/A0A8C2N4B2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q802T2-1", "protein_name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "gene_name": "ALG6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEKWSLMTITVLLALTVRWTVSLGSYSGAGKPPMYGDYEAQRHWQEVTYNLPIRQWYFNTSDNNLLYWGLDYPPLTAYHSFLCAYVAKLINPDWIALHTSRGYESQSHKLFMRTTVFVADLLIYIPAVILYCCSLKETSTKKKVSSALCILLYPGLILIDHGHFQYNSVSLGFALWGVLCLSYDWDLLGSAAFCLALNYKQMELYHSLPFFCYLLGKCFKKGLKGKGLLLLIKLAGTVVASFAVCWLPFCTDVEQIMQVLRRLFPIDRGLFEDKVANIWCSLSVLIKIKNVVSPQTQLKLSFAVTFLSLLPTCIKLTVQPSLRGFKLTLVSCALSFFLFSFQVHEKSILLVSVPVCLIINEVPFMATWFLLVSTFSMLPLLLKDGLLLPYAVTTLAFLSACVASFAIFEKTSAKDLQLKPFSQSLRGYVSWFKLFPKIVRSLFLLSVTLMGVLSVMSAAVHPPQRFPDLFPVSVSSISCLHFLFFLVYFNVIILWDSKNSRNQKKVS", "length": 507 }, "evidence": [ { "id": "A0A8C2N4B2", "url": "https://omabrowser.org/oma/group/A0A8C2N4B2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9FF17-1", "protein_name": "Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MPKKKPAKHSGEDDITIPVSPQTGSSIDTWWWLTHKGTTTSFLCISLFALLIRSAVTMYPYSGAGIPPKFGDFEAQRHWMEITTNLPVIDWYRNGTYNDLTYWGLDYPPLTAYQSYIHGIFLRFFNPESVALLSSRGHESYLGKLLMRWTVLSSDAFIFFPAALFFVLVYHRNRTRGGKSEVAWHIAMILLNPCLILIDHGHFQYNCISLGLTVGAIAAVLCESEVLTCVLFSLALSHKQMSAYFAPAFFSHLLGKCLRRKSPILSVIKLGIAVIVTFVIFWWPYVHSLDDFLMVLSRLAPFERGIYEDYVANFWCTTSILIKWKNLFTTQSLKSISLAATILASLPSMVQQILSPSNEGFLYGLLNSSMAFYLFSFQVHEKSILMPFLSATLLALKLPDHFSHLTYYALFSMFPLLCRDKLLIPYLTLSFLFTVIYHSPGNHHAIQKTDVSFFSFKNFPGYVFLLRTHFFISVVLHVLYLTIKPPQKYPFLFEALIMILCFSYFIMFAFYTNYTQWTLSSHFGSSDKEKKQI", "length": 533 }, "evidence": [ { "id": "A0A8C2N4B2", "url": "https://omabrowser.org/oma/group/A0A8C2N4B2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VKX7-1", "protein_name": "Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "gene_name": "gny", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRSEILASAFLGLAVRSIISLYSYSGFDSPPMHGDYEAQRHWQEITVNLAVGEWYTNSSNNDLQYWGLDYPPLTAYHSYLVGRIGASIDPRFVELHKSRGFESKEHKRFMRATVVSADVLIYLPAMLLLAYSLDKAFRSDDKLFLFTLVAAYPGQTLIDNGHFQYNNISLGFAAVAIAAILRRRFYAAAFFFTLALNYKQMELYHSLPFFAFLLGECVSQKSFASFIAEISRIAAVVLGTFAILWVPWLGSLQAVLQVLHRLFPVARGVFEDKVANVWCAVNVVWKLKKHISNDQMALVCIACTLIASLPTNVLLFRRRTNVGFLLALFNTSLAFFLFSFQVHEKTILLTALPALFLLKCWPDEMILFLEVTVFSMLPLLARDELLVPAVVATVAFHLIFKCFDSKSKLSNEYPLKYIANISQILMISVVVASLTVPAPTKYPDLWPLIISVTSCGHFFLFFLWGNVQQFSSKLS", "length": 475 }, "evidence": [ { "id": "A0A8C2N4B2", "url": "https://omabrowser.org/oma/group/A0A8C2N4B2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y672-1", "protein_name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "gene_name": "ALG6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKWYLMTVVVLIGLTVRWTVSLNSYSGAGKPPMFGDYEAQRHWQEITFNLPVKQWYFNSSDNNLQYWGLDYPPLTAYHSLLCAYVAKFINPDWIALHTSRGYESQAHKLFMRTTVLIADLLIYIPAVVLYCCCLKEISTKKKIANALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGISCDCDLLGSLAFCLAINYKQMELYHALPFFCFLLGKCFKKGLKGKGFVLLVKLACIVVASFVLCWLPFFTEREQTLQVLRRLFPVDRGLFEDKVANIWCSFNVFLKIKDILPRHIQLIMSFCSTFLSLLPACIKLILQPSSKGFKFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLSEIPFMSTWFLLVSTFSMLPLLLKDELLMPSVVTTMAFFIACVTSFSIFEKTSEEELQLKSFSISVRKYLPCFTFLSRIIQYLFLISVITMVLLTLMTVTLDPPQKLPDLFSVLVCFVSCLNFLFFLVYFNIIIMWDSKSGRNQKKIS", "length": 507 }, "evidence": [ { "id": "A0A8C2N4B2", "url": "https://omabrowser.org/oma/group/A0A8C2N4B2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity", "id": "GO:0042281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042281", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "30635", "name": "", "equation": "an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate = an alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8C2N4B2-1" ], "evidence": [ { "id": "30635", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30635" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8C2N4B2", "gene_name": "Alg6", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A8C2N4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N4B4-1", "uniprot_ac": "A0A8C2N4B4", "uniprot_id": "A0A8C2N4B4_CRIGR", "mass": { "chemical_mass": 29262.0, "monoisotopic_mass": 29262.0 }, "refseq": { "ac": "XP_003499714", "name": "palmitoyltransferase ZDHHC22", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499714" }, "gene_names": [ { "name": "Zdhhc22", "type": "recommended", "evidence": [ { "id": "A0A8C2N4B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4" } ] }, { "name": "Zdhhc22", "type": "synonym", "evidence": [ { "id": "XP_003499714", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499714" } ] } ], "protein_names": [ { "name": "Palmitoyltransferase", "type": "recommended", "evidence": [ { "id": "A0A8C2N4B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.225", "type": "synonym", "evidence": [ { "id": "A0A8C2N4B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4/entry#names_and_taxonomy" } ] }, { "name": "palmitoyltransferase ZDHHC22", "type": "synonym", "evidence": [ { "id": "XP_003499714", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499714" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613749.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003499714", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499714" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zdhhc22", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4", "locus": {} } ], "crossref": [ { "id": "100761833", "url": "https://www.ncbi.nlm.nih.gov/gene/100761833", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761833", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761833", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GQTWCQL", "url": "https://omabrowser.org/oma/group/GQTWCQL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N4B4", "url": "https://www.orthodb.org/?gene=A0A8C2N4B4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12246", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12246", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003499714", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499714", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36683", "url": "https://www.rhea-db.org/rhea/36683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N4B4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N4B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLALRLLNVVAPAYFLCISLVTFVLQLFLFLPSMREDPTATPLFSPALLHGALFLFLSANALGNYVLVIQNSPDDLGTCQATSSQRSQCPPPSTHFCRVCSRVTLRHDHHCFFTGNCIGSRNMRNFVLFCLYTSLACLYSMVAGVAYISAVLSISFSHPLAFLTLLPTSISQFFSGAVLGSDMFVILMLYLWFAVGLACAGFCCHQLLLILRGQTRYQVRKGVAVRARPWRKNLQEVFGKRWLLGLLVPMFNVGTESSKQQDK", "length": 263, "header": "tr|A0A8C2N4B4-1|A0A8C2N4B4_CRIGR Isoform 1 of Palmitoyltransferase OS=Cricetulus griseus OX=10029 GN=Zdhhc22 PE=3 SV=1 CANONICAL=A0A8C2N4B4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N4B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4/entry#A0A8C2N4B4-1", "sequence": { "sequence": "MLALRLLNVVAPAYFLCISLVTFVLQLFLFLPSMREDPTATPLFSPALLHGALFLFLSANALGNYVLVIQNSPDDLGTCQATSSQRSQCPPPSTHFCRVCSRVTLRHDHHCFFTGNCIGSRNMRNFVLFCLYTSLACLYSMVAGVAYISAVLSISFSHPLAFLTLLPTSISQFFSGAVLGSDMFVILMLYLWFAVGLACAGFCCHQLLLILRGQTRYQVRKGVAVRARPWRKNLQEVFGKRWLLGLLVPMFNVGTESSKQQDK", "length": 263, "header": "tr|A0A8C2N4B4-1|A0A8C2N4B4_CRIGR Isoform 1 of Palmitoyltransferase OS=Cricetulus griseus OX=10029 GN=Zdhhc22 PE=3 SV=1 CANONICAL=A0A8C2N4B4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761833", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761833", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XMA1-1", "protein_name": "Palmitoyltransferase", "gene_name": "ZDHHC22", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLVLRLLNVVAPAYFLCISLVTFVLQIFLFIPSMFRDPSTTPLFSPALLHGALFLFLSANALGNYILVIQSSPEELGKGLNLGEGAEMVADWLDGSRSPGSALPSTHYCRLCARVTQRHDHHCFFTGNCIGSRNMRNFIMFCLYTSLACLDSLVAGMAYISASLSMSFANPLAFLTLLPHSISQFFSGALLSSEMFVILMLYLWLGIGLACAGFCCHQLLLILRGQTRYQVRKGMVVRARPWRENLREVFGKRWLLGLLIPMLNVGSDCRRQKVK", "length": 275 }, "evidence": [ { "id": "A0A8C2N4B4", "url": "https://omabrowser.org/oma/group/A0A8C2N4B4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0PK84-1", "protein_name": "Palmitoyltransferase ZDHHC22", "gene_name": "Zdhhc22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRLLNVVAPAYFLCISLVTFVLQLFLFLPSMREDPTATPLFSPAVLHGALFLFLSANALGNYVLVIQNSPDDLGTCQGTMSQRPQCPPPSTHFCRVCSRVTLRHDHHCFFTGNCIGSRNMRNFILFCLYTSLACLYSMVAGVAYISAVLSISFAHPLAFLTLLPTSISQFFSGAVLGSDMFVILMLYLWFAVGLACAGFCCHQLLLILRGQTRYQVRKGMAVRARPWRKNLQEVFGKRWLLGLLVPMFNVGTESSKQQDK", "length": 263 }, "evidence": [ { "id": "A0A8C2N4B4", "url": "https://omabrowser.org/oma/group/A0A8C2N4B4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B987-1", "protein_name": "Palmitoyltransferase", "gene_name": "ZDHHC22", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLALRLLNVVAPAYFLCIALVTLVLQLFLFLPRMREDPTAARLFSPALLHGALFLFLSANALGNYVLVIQNSPDDLDACQGAEARRALCPPPSTHFCRVCARVTLRHDHHCFFTGNCIGSRNMRNFILFCLYTSLACLYSMVAGVAYISAVLSISFAHPLAFLTLLPTSISQFFSGAVLGSEMFVILMLYLWFAIGLACAGFCCHQLLLILRGQTRHQVRKGVAVRARPWRKNLQEVFGKRWLLGLLVPMFNVGSESCKQRDK", "length": 263 }, "evidence": [ { "id": "A0A8C2N4B4", "url": "https://omabrowser.org/oma/group/A0A8C2N4B4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q2TGI8-1", "protein_name": "Palmitoyltransferase ZDHHC22", "gene_name": "Zdhhc22", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLALRLLNVVAPAYFLCISLVTFVLQLFLFLPSMREDPTATPLFSPAVLHGALFLFLSANALGNYILVVQNSPDDLGACQGTSSQRPQRPPPSTHFCRVCARVTLRHDHHCFFTGNCIGSRNMRNFILFCLYTSLACLYSMVAGVAYISAVLSISFAHPLAFLTLLPTSISQFFSGAVLGSDMFVILMLYLWFAVGLACAGFCCHQLLLILRGQTRYQVRKGVAVRARPWRKNLQEVFGKRWLLGLLVPMFNVGTESSKQQDK", "length": 263 }, "evidence": [ { "id": "A0A8C2N4B4", "url": "https://omabrowser.org/oma/group/A0A8C2N4B4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N966-1", "protein_name": "Palmitoyltransferase ZDHHC22", "gene_name": "ZDHHC22", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLALRLLNVVAPAYFLCISLVTFVLQLFLFLPSMREDPAAARLFSPALLHGALFLFLSANALGNYVLVIQNSPDDLGACQGASARKTPCPSPSTHFCRVCARVTLRHDHHCFFTGNCIGSRNMRNFVLFCLYTSLACLYSMVAGVAYISAVLSISFAHPLAFLTLLPTSISQFFSGAVLGSEMFVILMLYLWFAIGLACAGFCCHQLLLILRGQTRHQVRKGVAVRARPWRKNLQEVFGKRWLLGLLVPMFNVGSESSKQQDK", "length": 263 }, "evidence": [ { "id": "A0A8C2N4B4", "url": "https://omabrowser.org/oma/group/A0A8C2N4B4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "X1WBB5-1", "protein_name": "Palmitoyltransferase ZDHHC22", "gene_name": "zdhhc22", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGKLKLLNTIAPAYFYAATVVTFALHFLLFTPTIFQSSDVTINPAMLAHISIFLFLMGNALGNYIMTIRNPSESANETVIPVCSPDCPDRIDAHYLLNGRHFCKVCKKVILKRDHHCFFTGNCIGNRNMRYFIMFSIYTSSSCLYSLVIGVAYLTIEYSISFENPLTFLTLLPLSTGYFFLGLISGLQFFLVIMLYIWLGIGLVSVGFCCQQLLLVARGQTWCELQKGQLSECRGTWRANLTDVFGSHWVLGLFVPVPTVETVPGNWQVYHDHKHD", "length": 276 }, "evidence": [ { "id": "A0A8C2N4B4", "url": "https://omabrowser.org/oma/group/A0A8C2N4B4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4B4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7FW69-1", "A0A9J7K4V8-1", "A0A061IAW6-1", "G3IC21-1", "G3HT13-1", "G3HRH7-1", "A0A9J7JWN6-1", "A0A9J7FYH6-1", "A0A9J7F608-1", "A0A9J7JS16-1", "A0A9J7FKQ2-1", "A0A8C2M959-1", "A0A9J7FES5-1", "A0A9J7FGJ2-1", "A0A8C2M019-1", "A0A8C2N4B4-1", "A0A061HVX4-1", "A0A061IE10-1", "A0A3L7HQY8-1", "A0A8C2LCM5-1", "A0A9J7JJ84-1", "A0A9J7H2R9-1", "A0A9J7GKL6-1", "A0A9J7GX65-1", "A0A9J7H176-1", "A0A9J7KAZ1-1", "A0A9J7JED5-1", "P04773-1" ], "evidence": [ { "id": "36683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36683" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HVX4", "gene_name": "Zdhhc15", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A061HVX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVX4" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A061HVX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVX4" } ] } ] }, { "uniprot_ac": "A0A061IAW6", "gene_name": "Zdhhc4", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A061IAW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAW6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A061IAW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAW6" } ] } ] }, { "uniprot_ac": "A0A061IE10", "gene_name": "Zdhhc24", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A061IE10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IE10" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A061IE10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IE10" } ] } ] }, { "uniprot_ac": "A0A3L7HQY8", "gene_name": "Zdhhc23", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3L7HQY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQY8" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A3L7HQY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQY8" } ] } ] }, { "uniprot_ac": "A0A8C2LCM5", "gene_name": "Zdhhc13", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8C2LCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCM5" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8C2LCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCM5" } ] } ] }, { "uniprot_ac": "A0A8C2M019", "gene_name": "Zdhhc2", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8C2M019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M019" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8C2M019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M019" } ] } ] }, { "uniprot_ac": "A0A8C2M959", "gene_name": "Zdhhc20", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8C2M959", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M959" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8C2M959", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M959" } ] } ] }, { "uniprot_ac": "A0A8C2N4B4", "gene_name": "Zdhhc22", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A8C2N4B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8C2N4B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4B4" } ] } ] }, { "uniprot_ac": "A0A9J7F608", "gene_name": "Zdhhc17", "activity": [ { "ec_number": "2.3.1.225", "activity": 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266187" } ] }, { "annotation": "Protein disulfide isomerase of the endoplasmic reticulum lumen involved in the formation of disulfide bonds in proteins. 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPRPGRLLPSLAGLPALAALLLLLGSRRGARAQEAAADGGAEQDPHAKHLYTADMFTHGIQSAAHFVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTANSDVCSAQGVRGYPTLKFFKPGQEAVKYQGPRDFETLENWMLQTLKEEPPTPEPEAEPPKAPELKQGLYELSANNFELHVSQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYGLCSENQVRGYPTLLWFRDGKKVDQYKGKRDLESLRDYVESQMQDPEVAPETVEPSEAPVLAAEPTGDKGTVLALTEKNFEDTIAQGITFVKFYAPWCGHCKNLAPTWEELSKKEFPGLAEVTVAKVDCTAERNVCTKYSVRGYPTLLLFRGGEKVGEHNGGRDLDSLHSFVLRQAKDEL", "length": 417, "header": "tr|A0A8C2N4D5-1|A0A8C2N4D5_CRIGR Isoform 1 of Thioredoxin domain-containing protein 5 OS=Cricetulus griseus OX=10029 GN=Txndc5 PE=3 SV=1 CANONICAL=A0A8C2N4D5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N4D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4D5/entry#A0A8C2N4D5-1", "sequence": { "sequence": 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4D5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4D5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766506", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766506", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4D5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4D5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4D5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4D5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4D5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4D5" } ], "pmid": "" }, { "name": "protein disulfide isomerase activity", "id": "GO:0003756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003756", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4D5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4D5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": 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"url": "https://www.uniprot.org/uniprotkb/A0A8C2N4J5" } ] }, { "name": "Fmnl2", "type": "synonym", "evidence": [ { "id": "XP_027276216", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276216" } ] } ], "protein_names": [ { "name": "Formin-like protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2N4J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4J5/entry#names_and_taxonomy" } ] }, { "name": "formin-like protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027276216", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276216" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 222 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) and transcript sequence (IACG01125821.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276216", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276216" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4J5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4J5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fmnl2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4J5", "locus": {} } ], "crossref": [ { "id": "100773842", "url": "https://www.ncbi.nlm.nih.gov/gene/100773842", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010472", "database": "InterPro", "categories": [ "Protein Classification" ] 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"length": 1090, "header": "tr|A0A8C2N4J5-1|A0A8C2N4J5_CRIGR Isoform 1 of Formin-like protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Fmnl2 PE=3 SV=1 CANONICAL=A0A8C2N4J5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4J5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4J5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773842", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773842", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4J5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4J5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4J5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4J5" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4J5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4J5" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4J5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4J5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4J5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4J5" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": 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Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 312 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615541.1) and transcript sequence (IACG01047235.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007651290.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007651290", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651290" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5U4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5U4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Atg16l1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5U4", "locus": {} } ], "crossref": [ { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22887", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22887", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": 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Classification" ] }, { "id": "IPR045160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771530", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771530", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N5U4", "url": "https://www.orthodb.org/?gene=A0A8C2N5U4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19878", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19878", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19878:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19878:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08614", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08614", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007651290", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651290", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N4N2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N4N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N5U4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N5U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5U4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSGLRAADFPRWKRHIAEELRRRDRLQRQAFEEIILQYTKLLEKSDLHSVLAQKLQAEKHDIPNRHEISPGHDGAWNDSQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQQKDREMQMNEAKIAECLQTISNLETECLDLRTKLQDLELANQTLKDEYDALQITFTALEEKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAVSRAATKRLSQPAGGLLDSITNIFGRRSVSSIPVPQDNVDTHPASGKDVRVPTTALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGDKCEFKSSLAGSNAGITSIEFDSAGAYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSECVVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYVWSVLTGKVEKVLSKQHSSSINAVAWAPSGMHVVSVDKGSKAVLWTQP", "length": 607, "header": "tr|A0A8C2N5U4-1|A0A8C2N5U4_CRIGR Isoform 1 of Autophagy-related protein 16-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Atg16l1 PE=3 SV=1 CANONICAL=A0A8C2N5U4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N4N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5U4/entry#A0A8C2N4N2-1", "sequence": { "sequence": "MSSGLRAADFPRWKRHIAEELRRRDRLQRQAFEEIILQYTKLLEKSDLHSVLAQKLQAEKHDIPNRHEISPGHDGAWNDSQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQQKDREMQMNEAKIAECLQTISNLETECLDLRTKLQDLELANQTLKDEYDALQITFTALEEKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAVSRAATRRSVSSIPVPQDNVDTHPASGKDVRVPTTALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGDKCEFKSSLAGSNAGITSIEFDSAGAYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSECVVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYVWSVLTGKVEKVLSKQHSSSINAVAWAPSGMHVVSVDKGSKAVLWTQP", "length": 588, "header": "tr|A0A8C2N4N2-1|A0A8C2N5U4_CRIGR Computationally mapped isoform of Autophagy-related protein 16-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Atg16l1 PE=3 SV=1 CANONICAL=A0A8C2N5U4-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N5U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5U4/entry#A0A8C2N5U4-1", "sequence": { "sequence": "MSSGLRAADFPRWKRHIAEELRRRDRLQRQAFEEIILQYTKLLEKSDLHSVLAQKLQAEKHDIPNRHEISPGHDGAWNDSQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQQKDREMQMNEAKIAECLQTISNLETECLDLRTKLQDLELANQTLKDEYDALQITFTALEEKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAVSRAATKRLSQPAGGLLDSITNIFGRRSVSSIPVPQDNVDTHPASGKDVRVPTTALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGDKCEFKSSLAGSNAGITSIEFDSAGAYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSECVVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYVWSVLTGKVEKVLSKQHSSSINAVAWAPSGMHVVSVDKGSKAVLWTQP", "length": 607, "header": "tr|A0A8C2N5U4-1|A0A8C2N5U4_CRIGR Isoform 1 of Autophagy-related protein 16-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Atg16l1 PE=3 SV=1 CANONICAL=A0A8C2N5U4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771530", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771530", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5U4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5U4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5U4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5U4" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5U4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5U4" } ], "pmid": "" }, { "name": "Atg12-Atg5-Atg16 complex", "id": "GO:0034274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034274", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5U4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5U4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5U4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5U4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N5U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5U4" }, { "id": "PF08614", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08614" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Autophagy-related protein 16", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 206, "start_aa": "His", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N4N7-1", "uniprot_ac": "A0A8C2N4N7", "uniprot_id": "A0A8C2N4N7_CRIGR", "mass": { "chemical_mass": 81572.0, "monoisotopic_mass": 81572.0 }, "refseq": { "ac": "XP_027254103", "name": "proton-associated sugar transporter A isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254103" }, "gene_names": [ { "name": "LOC100750542", "type": "recommended", "evidence": [ { "id": "A0A8C2N4N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N7" } ] }, { "name": "LOC100750542", "type": "synonym", "evidence": [ { "id": "XP_027254103", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254103" } ] } ], "protein_names": [ { "name": "Proton-associated sugar transporter A", "type": "recommended", "evidence": [ { "id": "A0A8C2N4N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N7/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 45 member 1", "type": "synonym", "evidence": [ { "id": "A0A8C2N4N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N7/entry#names_and_taxonomy" } ] }, { "name": "proton-associated sugar transporter A isoform X4", "type": "synonym", "evidence": [ { "id": "XP_027254103", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254103" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027254103", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254103" } ] }, { "annotation": "Proton-associated glucose transporter in the brain.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N7#function" }, { "database": "UniProtKB", "id": "ARBA00057104", "url": "https://www.uniprot.org/uniprotkb/ARBA00057104#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100750542", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N7", "locus": {} } ], "crossref": [ { "id": "cd17313", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17313", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100750542", "url": "https://www.ncbi.nlm.nih.gov/gene/100750542", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750542", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750542", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N4N7", "url": "https://www.orthodb.org/?gene=A0A8C2N4N7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19432", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19432", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19432:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19432:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027254103", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254103", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29019", "url": "https://www.rhea-db.org/rhea/29019", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69556", "url": "https://www.rhea-db.org/rhea/69556", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N4N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N4N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FD51", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FD51-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FD80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FD80-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIPPAGSTPPGEAAFPSAAAQDLWRSPASSYSGSVTRHISHRANNFKRHPKRRKCIRPSPPPPPNTPCPLELVDFGDLHPQRSFWELVFNGCILFGVEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGMALADTATDHKWGILLTVCGVVLMDFSADSADNPSHAYMMDVCGPVDQDRGLNIHALMAGLGGGFGYVVGGIHWDKTGFGRALGGQLRVIYIFTAITLSVTTVLTLISIPERPLRPLAEKRTAMKSPSLPLPPSPPVLLEEGAGDTLPSTTATSLYTSFSSPISPPSPLTPKYGSFISRDSSLTGLNEFASSFGTSNIDSVLIDCFTAGHDNYLALPSSAPRQAISVSFPRAPDGFYCQERGLLERREGALTSGSDGDVLRVGSLDTSKPRASGILKRPQTLALPDVARGNGPETSRRRNVTFSQQVANILLNGVKYESELTGSSEQSEQPLSLRRLCSTIYNMPKALRNLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEDCLSVRTLYFIAYLSFGLGTGLATLSRNLYVVLSLCTTYGILFSTLCTLPYSLLCDYYQSKKFAGSSADGTRRGMGMDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGCLYSSLCVTYEIPTGETADEEHQPLLLNV", "length": 752, "header": "tr|A0A8C2N4N7-1|A0A8C2N4N7_CRIGR Isoform 1 of Proton-associated sugar transporter A OS=Cricetulus griseus OX=10029 GN=LOC100750542 PE=3 SV=1 CANONICAL=A0A8C2N4N7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N4N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N7/entry#A0A8C2N4N7-1", "sequence": { "sequence": "MIPPAGSTPPGEAAFPSAAAQDLWRSPASSYSGSVTRHISHRANNFKRHPKRRKCIRPSPPPPPNTPCPLELVDFGDLHPQRSFWELVFNGCILFGVEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGMALADTATDHKWGILLTVCGVVLMDFSADSADNPSHAYMMDVCGPVDQDRGLNIHALMAGLGGGFGYVVGGIHWDKTGFGRALGGQLRVIYIFTAITLSVTTVLTLISIPERPLRPLAEKRTAMKSPSLPLPPSPPVLLEEGAGDTLPSTTATSLYTSFSSPISPPSPLTPKYGSFISRDSSLTGLNEFASSFGTSNIDSVLIDCFTAGHDNYLALPSSAPRQAISVSFPRAPDGFYCQERGLLERREGALTSGSDGDVLRVGSLDTSKPRASGILKRPQTLALPDVARGNGPETSRRRNVTFSQQVANILLNGVKYESELTGSSEQSEQPLSLRRLCSTIYNMPKALRNLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEDCLSVRTLYFIAYLSFGLGTGLATLSRNLYVVLSLCTTYGILFSTLCTLPYSLLCDYYQSKKFAGSSADGTRRGMGMDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGCLYSSLCVTYEIPTGETADEEHQPLLLNV", "length": 752, "header": "tr|A0A8C2N4N7-1|A0A8C2N4N7_CRIGR Isoform 1 of Proton-associated sugar transporter A OS=Cricetulus griseus OX=10029 GN=LOC100750542 PE=3 SV=1 CANONICAL=A0A8C2N4N7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FD51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N7/entry#A0A9J7FD51-1", "sequence": { "sequence": "MALADTATDHKWGILLTVCGVVLMDFSADSADNPSHAYMMDVCGPVDQDRGLNIHALMAGLGGGFGYVVGGIHWDKTGFGRALGGQLRVIYIFTAITLSVTTVLTLISIPERPLRPLAEKRTAMKSPSLPLPPSPPVLLEEGAGDTLPSTTATSLYTSFSSPISPPSPLTPKYGSFISRDSSLTGLNEFASSFGTSNIDSVLIDCFTAGHDNYLALPSSAPRQAISVSFPRAPDGFYCQERGLLERREGALTSGSDGDVLRVGSLDTSKPRASGILKRPQTLALPDVARGNGPETSRRRNVTFSQQVANILLNGVKYESELTGSSEQSEQPLSLRRLCSTIYNMPKALRNLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEDCLSVRTLYFIAYLSFGLGTGLATLSRNLYVVLSLCTTYGILFSTLCTLPYSLLCDYYQSKKFAGSSADGTRRGMGMDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGCLYSSLCVTYEIPTGETADEEHQPLLLNV", "length": 573, "header": "tr|A0A9J7FD51-1|A0A8C2N4N7_CRIGR Computationally mapped isoform of Proton-associated sugar transporter A OS=Cricetulus griseus OX=10029 GN=LOC100750542 PE=3 SV=1 CANONICAL=A0A8C2N4N7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FD80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N7/entry#A0A9J7FD80-1", "sequence": { "sequence": "MIPPAGSTPPGEAAFPSAAAQDLWRSPASSYSGSVTRHISHRANNFKRHPKRRKCIRPSPPPPPNTPCPLELVDFGDLHPQRSFWELVFNGCILFGVEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGMALADTATDHKWGILLTVCGVVLMDFSADSADNPSHAYMMDVCGPVDQDRGLNIHALMAGLGGGFGYVVGGIHWDKTGFGRALGGQLRVIYIFTAITLSVTTVLTLISIPERPLRPLAEKRTAMKSPSLPLPPSPPVLLEEGAGDTLPSTTATSLYTSFSSPISPPSPLTPKYGSFISRDSSLTGLNEFASSFGTSNIDSVLIDCFTAGHDNYLALPSSAPRQAISVSFPRAPDGFYCQERGLLERREGALTSGSDGDVLRVGSLDTSKPRASGILKRPQTLALPDVARGNGPETSRRRNVTFSQQVANILLNGVKYESELTGSSEQSEQPLSLRRLCSTIYNMPKALRNLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSVCRVQRRRHSAWHGNGHLAT", "length": 615, "header": "tr|A0A9J7FD80-1|A0A8C2N4N7_CRIGR Computationally mapped isoform of Proton-associated sugar transporter A OS=Cricetulus griseus OX=10029 GN=LOC100750542 PE=3 SV=1 CANONICAL=A0A8C2N4N7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 109, "start_aa": "Thr", "end_pos": 109, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr109", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 8, "start_aa": "Thr", "end_pos": 8, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr8", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FD51", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD51" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FD51", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD51" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750542", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750542", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "D-glucose transmembrane transport", "id": "GO:1904659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904659", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "sucrose:proton symporter activity", "id": "GO:0008506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008506", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N7" } ], "pmid": "" }, { "name": "D-glucose:proton symporter activity", "id": "GO:0005356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005356", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 479, "end_pos": 481, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29019", "name": "", "equation": "D-galactose(in) + H(+)(in) = D-galactose(out) + H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29019", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29019" } ] }, { "id": "69556", "name": "", "equation": "D-glucose(out) + H(+)(out) = D-glucose(in) + H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "69556", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69556" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 8, 109 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 479, "end_pos": 481 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N4N8-1", "uniprot_ac": "A0A8C2N4N8", "uniprot_id": "A0A8C2N4N8_CRIGR", "mass": { "chemical_mass": 42213.0, "monoisotopic_mass": 42213.0 }, "refseq": { "ac": "XP_035295088", "name": "membrane protein MLC1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295088" }, "gene_names": [ { "name": "Mlc1", "type": "recommended", "evidence": [ { "id": "A0A8C2N4N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ] }, { "name": "Mlc1", "type": "synonym", "evidence": [ { "id": "XP_035295088", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295088" } ] } ], "protein_names": [ { "name": "Membrane protein MLC1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2N4N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8/entry#names_and_taxonomy" } ] }, { "name": "membrane protein MLC1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035295088", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295088" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035295088", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295088" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mlc1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8", "locus": {} } ], "crossref": [ { "id": "100758882", "url": "https://www.ncbi.nlm.nih.gov/gene/100758882", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758882", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758882", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KAWRAVM", "url": "https://omabrowser.org/oma/group/KAWRAVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N4N8", "url": "https://www.orthodb.org/?gene=A0A8C2N4N8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17597", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17597", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17597:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17597:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27925", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27925", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035295088", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295088", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N4N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GQP9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GQP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVSSAMTREGQFREELGYDRMPTLERGRQDTGRQDAGSYTPDSKPKDLQLSKRLPPCFSYKTWVFSVLMGSCLLVTSGFSLYLGNVFPSEMDYLRCAAGSCIPSAIVSFAVGKRNVSAIPNFQILFVSTFAVTTTCLIWFGCKLILNPSAININFNLILLLLLELLMAATVIISARSSEESCKKKKVSISDGTNILDEVTFPARVLKSYSVVEVIAGVSAVLGGVIALNVDEAVSGPHLSVTFFWILVACFPSAIASHVTAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSVMRIVEIFKDYPPAIKSYDVLLLLLLLVLLLQGGLNTGTAIQCVSFKVSTQQQAASWDTQTCPQERPAGEVARSPLKEFDKEKAWRAVVVQMAQ", "length": 388, "header": "tr|A0A8C2N4N8-1|A0A8C2N4N8_CRIGR Isoform 1 of Membrane protein MLC1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mlc1 PE=4 SV=1 CANONICAL=A0A8C2N4N8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N4N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8/entry#A0A8C2N4N8-1", "sequence": { "sequence": "MPVSSAMTREGQFREELGYDRMPTLERGRQDTGRQDAGSYTPDSKPKDLQLSKRLPPCFSYKTWVFSVLMGSCLLVTSGFSLYLGNVFPSEMDYLRCAAGSCIPSAIVSFAVGKRNVSAIPNFQILFVSTFAVTTTCLIWFGCKLILNPSAININFNLILLLLLELLMAATVIISARSSEESCKKKKVSISDGTNILDEVTFPARVLKSYSVVEVIAGVSAVLGGVIALNVDEAVSGPHLSVTFFWILVACFPSAIASHVTAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSVMRIVEIFKDYPPAIKSYDVLLLLLLLVLLLQGGLNTGTAIQCVSFKVSTQQQAASWDTQTCPQERPAGEVARSPLKEFDKEKAWRAVVVQMAQ", "length": 388, "header": "tr|A0A8C2N4N8-1|A0A8C2N4N8_CRIGR Isoform 1 of Membrane protein MLC1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mlc1 PE=4 SV=1 CANONICAL=A0A8C2N4N8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GQP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8/entry#A0A9J7GQP9-1", "sequence": { "sequence": "MPVSSAMTREGQFREELGYDRMPTLERGRQDTGRQDAGSYTPDSKPKDLQLSKRLPPCFSYKTWVFSVLMGSCLLVTSGFSLYLGNVFPSEMDYLRCAAGSCIPSAIVSFAVGKRNVSAIPNFQILFVSTFAVTTTCLIWFGCKLILNPSAININFNLILLLLLELLMAATVIISARSSEESCKKKKVSISDGTNILDEVTFPARVLKSYSVVEVIAGVSAVLGGVIALNVDEAVSGPHLSVTFFWILVACFPSAIASHVTAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSVMRIVEIFKDYPPAIKVARSPLKEFDKEKAWRAVVVQMAQ", "length": 334, "header": "tr|A0A9J7GQP9-1|A0A9J7GQP9_CRIGR Computationally mapped isoform of Membrane protein MLC1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Mlc1 PE=4 SV=1 CANONICAL=A0A8C2N4N8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758882", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758882", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PIT5-1", "protein_name": "Modulator of VRAC current 1", "gene_name": "MLC1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTREEGYREEFSYDRMPTLERGKQENGNYIPDIKSSDLQLSKRLHPCFIYRTWIFSLLMGSCLLITSGFSLYLGNIFPSEMDYLRCAAGSCIPSAVVSFAIARNKINVIPNFQILFVSTFAVTTTCLIWFGCKLVLNPSAININFNLILLILLEIFMATTVIISARSTEDCCMRKKNTTYDSAVVLSNVSFPARILKSYSVIEVIIGISSVFGGIIALNMDVLVSGPYLSVTFFWILVACFPSAIASHVAAEYPSKCLVEVLIAISSVTSPLLFTASGYLSFSIMQVVDIFKNYPPPVKQSYDVLLLLLMLMLLIQACLTIGTVIQCVNYKTKMKLQDSSWTESQVKKQEYRTTEVSNNTLKDFDKDKAWKAVVVQMAQ", "length": 379 }, "evidence": [ { "id": "A0A8C2N4N8", "url": "https://omabrowser.org/oma/group/A0A8C2N4N8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ABB2-1", "protein_name": "Modulator of VRAC current 1", "gene_name": "Mlc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNTSCWKSITQRPALPTAGPQQSAMTREGQFREELGYDRMPTLERGRQDAGRQDTGSYTPDTKPKDLQLTKRLPPCFSYKTWVFSVLMGSCLLVTSGFSLYLGNVFPSEMDYLRCAAGSCIPSAIVSFAVGRRNVSAIPNFQILFVSTFAVTTTCLIWFGCKLILNPSAININFNLILLLLLELLMAATVIISARSSEEPCKKKKVGLPQLPPHAPEGSISDGTNILDEVTFPARVLKSYSVVEVIAGVSAVLGGVIALNVEEAVSGPHLSVTFFWILVACFPSAIASHVTAECPSKCLVEVLITISSLTSPLLFTASGYLSFSVMRIVEIFKDYPPDIKSYDVLLLLLLLLLLLQGGLNTGTAIQCVSFKVSARLQAASWDSQSCPQERPAGEVVRSPLKEFDKEKAWRAVVVQMAQ", "length": 418 }, "evidence": [ { "id": "A0A8C2N4N8", "url": "https://omabrowser.org/oma/group/A0A8C2N4N8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RXR5-1", "protein_name": "Modulator of VRAC current 1", "gene_name": "MLC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAREEQCREELGYDRAPTLERGRPDARSYTPDAKPSDLQLSSRLPPCFSHKTWVLSVLMGSCLLVTSGFSLYLGNVFPSEMDYLRCAAGSCIPSAIVSFAVSRRNVSAIPNFQILFVSSFAVTTTCLIWFGCKLVLNPSAVDINFNLILLLLLELLVAATVIMSARSGEARCRRKGSVSESTNILYEVAFPGRVLKSYSVIEVMAGISAVLGGVIALNVDDAVSGPHFSVAFFWILVACFPSAIASHVTAECPSRCLVEVLAAICSLAAPLLFTASGYLSVSVLRVTELFKDYPPAFKQSHDVLLLLLMLELLLQAGLNTATVIQCVNFKVGAAWDAAQTGQQERPAGEVARSPLKEFDKEKAWRAVVVQMAQ", "length": 373 }, "evidence": [ { "id": "A0A8C2N4N8", "url": "https://omabrowser.org/oma/group/A0A8C2N4N8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q15049-1", "protein_name": "Membrane protein MLC1", "gene_name": "MLC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTQEPFREELAYDRMPTLERGRQDPASYAPDAKPSDLQLSKRLPPCFSHKTWVFSVLMGSCLLVTSGFSLYLGNVFPAEMDYLRCAAGSCIPSAIVSFTVSRRNANVIPNFQILFVSTFAVTTTCLIWFGCKLVLNPSAININFNLILLLLLELLMAATVIIAARSSEEDCKKKKGSMSDSANILDEVPFPARVLKSYSVVEVIAGISAVLGGIIALNVDDSVSGPHLSVTFFWILVACFPSAIASHVAAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSIMRIVEMFKDYPPAIKPSYDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLKEFDKEKAWRAVVVQMAQ", "length": 377 }, "evidence": [ { "id": "A0A8C2N4N8", "url": "https://omabrowser.org/oma/group/A0A8C2N4N8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VHK5-1", "protein_name": "Membrane protein MLC1", "gene_name": "Mlc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTREGQFREELGYDRMPTLERGRQDAGRQDPGSYTPDSKPKDLQLSKRLPPCFSYKTWVFSVLMGSCLLVTSGFSLYLGNVFPSEMDYLRCAAGSCIPSAIVSFAVGRRNVSAIPNFQILFVSTFAVTTTCLIWFGCKLILNPSAININFNLILLLLLELLMAATVIISARSSEEPCKKKKGSISDGSNILDEVTFPARVLKSYSVVEVIAGVSAVLGGVIALNVEEAVSGPHLSVTFFWILVACFPSAIASHVTAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSVMRVVEIFKDYPPAIKSYDVLLLLLLLLLLLQGGLNTGTAIQCVSFKVSARLQAASWDPQSCPQERPAGEVVRGPLKEFDKEKAWRAVVVQMAQ", "length": 382 }, "evidence": [ { "id": "A0A8C2N4N8", "url": "https://omabrowser.org/oma/group/A0A8C2N4N8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "pmid": "" }, { "name": "astrocyte end-foot", "id": "GO:0097450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097450", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of intracellular transport", "id": "GO:0032388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032388", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "pmid": "" }, { "name": "regulation of response to osmotic stress", "id": "GO:0047484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047484", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4N8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N4T4-1", "uniprot_ac": "A0A8C2N4T4", "uniprot_id": "A0A8C2N4T4_CRIGR", "mass": { "chemical_mass": 29713.0, "monoisotopic_mass": 29713.0 }, "refseq": { "ac": "XP_035306255", "name": "myozenin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306255" }, "gene_names": [ { "name": "Myoz2", "type": "recommended", "evidence": [ { "id": "A0A8C2N4T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4T4" } ] }, { "name": "Myoz2", "type": "synonym", "evidence": [ { "id": "XP_035306255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306255" } ] } ], "protein_names": [ { "name": "Myozenin-2", "type": "synonym", "evidence": [ { "id": "A0A8C2N4T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4T4/entry#names_and_taxonomy" } ] }, { "name": "myozenin-2", "type": "synonym", "evidence": [ { "id": "XP_035306255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306255" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. 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RNA-binding protein Nova-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Nova1 PE=4 SV=1 CANONICAL=A0A8C2N4U8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N4U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4U8/entry#A0A8C2N4U8-1", "sequence": { "sequence": "MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAIMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQKVG", "length": 507, "header": "tr|A0A8C2N4U8-1|A0A8C2N4U8_CRIGR Isoform 1 of RNA-binding protein Nova-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Nova1 PE=4 SV=1 CANONICAL=A0A8C2N4U8-1" }, "locus": {} }, { "isoform_ac": 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"MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQMVKGERKGPRQCLHVTEEKPFLKTSIV", "length": 200, "header": "tr|A0A9J7JSG4-1|A0A8C2N4U8_CRIGR Computationally mapped isoform of RNA-binding protein Nova-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Nova1 PE=4 SV=1 CANONICAL=A0A8C2N4U8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JTS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4U8/entry#A0A9J7JTS4-1", "sequence": { "sequence": "MPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAIMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQKVG", "length": 385, "header": "tr|A0A9J7JTS4-1|A0A8C2N4U8_CRIGR Computationally mapped isoform of RNA-binding protein Nova-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Nova1 PE=4 SV=1 CANONICAL=A0A8C2N4U8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K5X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4U8/entry#A0A9J7K5X2-1", "sequence": { "sequence": "MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQCFISQQKLHG", "length": 183, "header": "tr|A0A9J7K5X2-1|A0A8C2N4U8_CRIGR Computationally mapped isoform of RNA-binding protein Nova-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Nova1 PE=4 SV=1 CANONICAL=A0A8C2N4U8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"A0A8C2N4U8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4U8" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4U8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4U8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4U8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4U8" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4U8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4U8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": 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"protein_names": [ { "name": "WD repeat and FYVE domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8C2N4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4V2/entry#names_and_taxonomy" } ] }, { "name": "WD repeat and FYVE domain-containing protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027253149", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253149" } ] }, { "name": "WD40- and FYVE domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A8C2N4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4V2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version 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"length": 1107, "header": "tr|A0A8C2N4W8-1|A0A8C2N4W8_CRIGR Isoform 1 of Transmembrane protein 132C isoform X2 OS=Cricetulus griseus OX=10029 GN=Tmem132c PE=3 SV=1 CANONICAL=A0A8C2N4W8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4W8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N4Z3-1", "uniprot_ac": "A0A8C2N4Z3", "uniprot_id": "A0A8C2N4Z3_CRIGR", "mass": { "chemical_mass": 48828.0, "monoisotopic_mass": 48828.0 }, "refseq": { "ac": "XP_027265112", "name": "transcription factor E2F3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265112" }, "gene_names": [ { "name": "E2f3", "type": "recommended", "evidence": [ { "id": "A0A8C2N4Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3" } ] }, { "name": "E2f3", "type": "synonym", "evidence": [ { 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This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265112", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265112" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "E2f3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3", "locus": {} } ], "crossref": [ { "id": "cd14660", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14660", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754647", "url": "https://www.ncbi.nlm.nih.gov/gene/100754647", "database": "GeneID", "categories": [ "Genome 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"https://www.uniprot.org/uniprotkb/A0A9J7FU80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAPGTYIQILTTNPSTTSCATSLQSSTLAAGPLLPSVPGAEPTAGSLLYSTPQGPSSRAGLLQQPPAPGRGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHRPMKTNNQDHNGNIPKPTSKDLASNNSGHSDCSVSTANLSPLASPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS", "length": 458, "header": "tr|A0A8C2N4Z3-1|A0A8C2N4Z3_CRIGR Isoform 1 of Transcription factor E2F3 isoform X1 OS=Cricetulus griseus OX=10029 GN=E2f3 PE=3 SV=1 CANONICAL=A0A8C2N4Z3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N4Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3/entry#A0A8C2N4Z3-1", "sequence": { "sequence": "MRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAPGTYIQILTTNPSTTSCATSLQSSTLAAGPLLPSVPGAEPTAGSLLYSTPQGPSSRAGLLQQPPAPGRGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHRPMKTNNQDHNGNIPKPTSKDLASNNSGHSDCSVSTANLSPLASPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS", "length": 458, "header": "tr|A0A8C2N4Z3-1|A0A8C2N4Z3_CRIGR Isoform 1 of Transcription factor E2F3 isoform X1 OS=Cricetulus griseus OX=10029 GN=E2f3 PE=3 SV=1 CANONICAL=A0A8C2N4Z3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FQD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3/entry#A0A9J7FQD1-1", "sequence": { "sequence": "MPLQQQAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKKKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHRPMKTNNQDHNGNIPKPTSKDLASNNSGHSDCSVSTANLSPLASPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS", "length": 334, "header": "tr|A0A9J7FQD1-1|A0A8C2N4Z3_CRIGR Computationally mapped isoform of Transcription factor E2F3 isoform X1 OS=Cricetulus griseus OX=10029 GN=E2f3 PE=3 SV=1 CANONICAL=A0A8C2N4Z3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FSE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3/entry#A0A9J7FSE6-1", "sequence": { "sequence": "MRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAPGTYIQILTTNPSTTSCATSLQSSTLAAGPLLPSVPGAEPTAGSLLYSTPQGPSSRAGLLQQPPAPGRGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKKKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHRPMKTNNQDHNGNIPKPTSKDLASNNSGHSDCSVSTANLSPLASPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS", "length": 452, "header": "tr|A0A9J7FSE6-1|A0A8C2N4Z3_CRIGR Computationally mapped isoform of Transcription factor E2F3 isoform X1 OS=Cricetulus griseus OX=10029 GN=E2f3 PE=3 SV=1 CANONICAL=A0A8C2N4Z3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FU80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3/entry#A0A9J7FU80-1", "sequence": { "sequence": "MPLQQQAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHRPMKTNNQDHNGNIPKPTSKDLASNNSGHSDCSVSTANLSPLASPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS", "length": 340, "header": "tr|A0A9J7FU80-1|A0A8C2N4Z3_CRIGR Computationally mapped isoform of Transcription factor E2F3 isoform X1 OS=Cricetulus griseus OX=10029 GN=E2f3 PE=3 SV=1 CANONICAL=A0A8C2N4Z3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 90, "start_aa": "Thr", "end_pos": 90, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr90", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQD1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQD1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQD1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQD1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754647", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754647", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of fat cell proliferation", "id": "GO:0070345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070345", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3" } ], "pmid": "" }, { "name": "positive regulation of vascular associated smooth muscle cell apoptotic process", "id": "GO:1905461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905461", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N4Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N4Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4Z3" }, { "id": "SM01372", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01372" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "E2F/DP family winged-helix DNA-binding", "eco_id": "ECO_0000259", "start_pos": 171, "end_pos": 236, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 90 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 376, "end_pos": 378 }, { "start_pos": 389, "end_pos": 391 } ] }, "class_list": [], "section_stats": [ { 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"sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N555-1", "uniprot_ac": "A0A8C2N555", "uniprot_id": "A0A8C2N555_CRIGR", "mass": { "chemical_mass": 84448.0, "monoisotopic_mass": 84448.0 }, "refseq": { "ac": "XP_027270625", "name": "transducin-like enhancer protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270625" }, "gene_names": [ { "name": "Tle3", "type": "recommended", "evidence": [ { "id": "A0A8C2N555", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555" } ] }, { "name": "Tle3", "type": "synonym", "evidence": [ { "id": "XP_027270625", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270625" } ] } ], "protein_names": [ { "name": "Transducin-like enhancer protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2N555", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555/entry#names_and_taxonomy" } ] }, { "name": "transducin-like enhancer protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027270625", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270625" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027270625", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270625" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N555", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tle3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555", "locus": {} } ], "crossref": [ { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754091", "url": "https://www.ncbi.nlm.nih.gov/gene/100754091", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754091", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754091", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N555", "url": "https://www.orthodb.org/?gene=A0A8C2N555", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FZI8", "url": "https://www.orthodb.org/?gene=A0A9J7FZI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10814", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10814", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10814:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10814:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027270625", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270625", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N555", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N555-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWJ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FX50", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FX50-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FY92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FY92-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZI8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0N1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JP84", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JP84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JP84-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JP84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQ99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQ99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQ99-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQ99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQU7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGVRGLPNLPLTQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAVKDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAPTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIGIMASALRTPISLTSSYAAPFAMMSHHEMNGSLTSPSAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY", "length": 782, "header": "tr|A0A8C2N555-1|A0A8C2N555_CRIGR Isoform 1 of Transducin-like enhancer protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tle3 PE=3 SV=1 CANONICAL=A0A8C2N555-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N555-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555/entry#A0A8C2N555-1", "sequence": { "sequence": "MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGVRGLPNLPLTQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAVKDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAPTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIGIMASALRTPISLTSSYAAPFAMMSHHEMNGSLTSPSAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY", "length": 782, "header": "tr|A0A8C2N555-1|A0A8C2N555_CRIGR Isoform 1 of Transducin-like enhancer protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tle3 PE=3 SV=1 CANONICAL=A0A8C2N555-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FWJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555/entry#A0A9J7FWJ1-1", "sequence": { "sequence": "MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAVKDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAPTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIGIMASALRTPISLTSSYAAPFAMMSHHEMNGSLTSPSAYAGLHNIPPQMSAAAAAAAAAYGRSPMVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY", "length": 767, "header": "tr|A0A9J7FWJ1-1|A0A8C2N555_CRIGR Computationally mapped isoform of Transducin-like enhancer protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tle3 PE=3 SV=1 CANONICAL=A0A8C2N555-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FX50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555/entry#A0A9J7FX50-1", "sequence": { "sequence": "MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAVKDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAPTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIGIMASALRTPISLTSSYAAPFAMMSHHEMNGSLTSPSAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY", "length": 771, "header": "tr|A0A9J7FX50-1|A0A8C2N555_CRIGR Computationally mapped isoform of Transducin-like enhancer protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tle3 PE=3 SV=1 CANONICAL=A0A8C2N555-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FXH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555/entry#A0A9J7FXH7-1", "sequence": { "sequence": "MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGVRGLPNLPLTQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAVKDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAPTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIASALRTPISLTSSYAAPFAMMSHHEMNGSLTSPSAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY", "length": 779, "header": "tr|A0A9J7FXH7-1|A0A8C2N555_CRIGR Computationally mapped isoform of Transducin-like enhancer protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tle3 PE=3 SV=1 CANONICAL=A0A8C2N555-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FY92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555/entry#A0A9J7FY92-1", "sequence": { "sequence": "MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAVKDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAPTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIASALRTPISLTSSYAAPFAMMSHHEMNGSLTSPSAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY", "length": 769, "header": "tr|A0A9J7FY92-1|A0A8C2N555_CRIGR Computationally mapped isoform of Transducin-like enhancer protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tle3 PE=3 SV=1 CANONICAL=A0A8C2N555-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555/entry#A0A9J7FZI8-1", "sequence": { "sequence": "MPFLSQEHQQQVAQAVERAKQVTMTELNAIIGVRGLPNLPLTQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAVKDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAPTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIGIMASALRTPISLTSSYAAPFAMMSHHEMNGSLTSPSAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY", "length": 690, "header": "tr|A0A9J7FZI8-1|A0A8C2N555_CRIGR Computationally mapped isoform of Transducin-like enhancer protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tle3 PE=3 SV=1 CANONICAL=A0A8C2N555-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555/entry#A0A9J7FZK3-1", "sequence": { "sequence": "MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAVKDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAPTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIASALRTPISLTSSYAAPFAMMSHHEMNGSLTSPSAYAGLHNIPPQMSAAAAAAAAAYGRSPMVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY", "length": 763, "header": "tr|A0A9J7FZK3-1|A0A8C2N555_CRIGR Computationally mapped isoform of Transducin-like enhancer protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tle3 PE=3 SV=1 CANONICAL=A0A8C2N555-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G0N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555/entry#A0A9J7G0N1-1", "sequence": { "sequence": "MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAVKDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAPTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIGIMASALRTPISLTSSYAAPFAMMSHHEMNGSLTSPSAYAGLHNIPPQMSAAAAAAAAAYGRSPMVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY", "length": 766, "header": "tr|A0A9J7G0N1-1|A0A8C2N555_CRIGR Computationally mapped isoform of Transducin-like enhancer protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tle3 PE=3 SV=1 CANONICAL=A0A8C2N555-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555/entry#A0A9J7JHM3-1", "sequence": { "sequence": "MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGVRGLPNLPLTQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAVKDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAPTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIGIMASALRTPISLTSSYAAPFAMMSHHEMNGSLTSPSAYAGLHNIPPQMSAAAAAAAAAYGRSPMVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY", "length": 777, "header": "tr|A0A9J7JHM3-1|A0A8C2N555_CRIGR Computationally mapped isoform of Transducin-like enhancer protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tle3 PE=3 SV=1 CANONICAL=A0A8C2N555-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JMC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555/entry#A0A9J7JMC9-1", "sequence": { "sequence": "MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGVRGLPNLPLTQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAVKDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAPTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIGIMASALRTPISLTSSYAAPFAMMSHHEMNGSLTSPSAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY", "length": 781, "header": "tr|A0A9J7JMC9-1|A0A8C2N555_CRIGR Computationally mapped isoform of Transducin-like enhancer protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tle3 PE=3 SV=1 CANONICAL=A0A8C2N555-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JP84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555/entry#A0A9J7JP84-1", "sequence": { "sequence": "MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAVKDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAPTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIGIMASALRTPISLTSSYAAPFAMMSHHEMNGSLTSPSAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY", "length": 772, "header": "tr|A0A9J7JP84-1|A0A8C2N555_CRIGR Computationally mapped isoform of Transducin-like enhancer protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tle3 PE=3 SV=1 CANONICAL=A0A8C2N555-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQ99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555/entry#A0A9J7JQ99-1", "sequence": { "sequence": "MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGVRGLPNLPLTQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAVKDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAPTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIASALRTPISLTSSYAAPFAMMSHHEMNGSLTSPSAYAGLHNIPPQMSAAAAAAAAAYGRSPMVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY", "length": 774, "header": "tr|A0A9J7JQ99-1|A0A8C2N555_CRIGR Computationally mapped isoform of Transducin-like enhancer protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tle3 PE=3 SV=1 CANONICAL=A0A8C2N555-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555/entry#A0A9J7JQU7-1", "sequence": { "sequence": "MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAVKDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAPTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIASALRTPISLTSSYAAPFAMMSHHEMNGSLTSPSAYAGLHNIPPQMSAAAAAAAAAYGRSPMVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY", "length": 764, "header": "tr|A0A9J7JQU7-1|A0A8C2N555_CRIGR Computationally mapped isoform of Transducin-like enhancer protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tle3 PE=3 SV=1 CANONICAL=A0A8C2N555-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 306, "start_aa": "Thr", "end_pos": 306, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr306", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 338, "start_aa": "Thr", "end_pos": 338, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr338", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWJ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWJ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754091", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754091", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N555", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N555", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N555", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N555", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N555", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N555", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N555" }, { "id": "PF03920", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03920" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Groucho/TLE N-terminal Q-rich", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 143, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 306, 338 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 209, "end_pos": 211 }, { "start_pos": 390, "end_pos": 392 }, { "start_pos": 617, "end_pos": 619 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N588-1", "uniprot_ac": "A0A8C2N588", "uniprot_id": "A0A8C2N588_CRIGR", "mass": { "chemical_mass": 44405.0, "monoisotopic_mass": 44405.0 }, "refseq": { "ac": "XP_003503660", "name": "homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503660" }, "gene_names": [ { "name": "Herpud1", "type": "recommended", "evidence": [ { "id": "A0A8C2N588", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ] }, { "name": "Herpud1", "type": "synonym", "evidence": [ { "id": "XP_003503660", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503660" } ] } ], "protein_names": [ { "name": "Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2N588", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588/entry#names_and_taxonomy" } ] }, { "name": "homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003503660", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503660" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613984.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003503660", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503660" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Herpud1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588", "locus": {} } ], "crossref": [ { "id": "cd17118", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17118", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758367", "url": "https://www.ncbi.nlm.nih.gov/gene/100758367", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758367", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758367", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MSTAWVF", "url": "https://omabrowser.org/oma/group/MSTAWVF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N588", "url": "https://www.orthodb.org/?gene=A0A8C2N588", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FMI4", "url": "https://www.orthodb.org/?gene=A0A9J7FMI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12943", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12943", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12943:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12943:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003503660", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503660", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N588-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FMI4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FMI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPEPQPEQVTLLVKSPNQRHRDLELSGDRSWSVSRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLPKQEKRHVLHLVCNVKNPSKMLEAKTKGAESTEQPANTDQAQHPQAQHPGDSSGDGLRQREVLRNLSPSGWENISRPEAVQQAFQGLGPGFSGYTTYGWLQLSWFQQIYARQYYMQYLAATAASGAFVPTPSAQEIPVVSTPTPAPIHNQFPAENQPANQNAAAQVVVNPGANQNLRMNAQGGPLVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPDDGPPQEAANQDPNNNLQEGTDPETEDPNSLPPDHEVLDPEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN", "length": 396, "header": "tr|A0A8C2N588-1|A0A8C2N588_CRIGR Isoform 1 of Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Herpud1 PE=4 SV=1 CANONICAL=A0A8C2N588-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N588-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588/entry#A0A8C2N588-1", "sequence": { "sequence": "MEPEPQPEQVTLLVKSPNQRHRDLELSGDRSWSVSRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLPKQEKRHVLHLVCNVKNPSKMLEAKTKGAESTEQPANTDQAQHPQAQHPGDSSGDGLRQREVLRNLSPSGWENISRPEAVQQAFQGLGPGFSGYTTYGWLQLSWFQQIYARQYYMQYLAATAASGAFVPTPSAQEIPVVSTPTPAPIHNQFPAENQPANQNAAAQVVVNPGANQNLRMNAQGGPLVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPDDGPPQEAANQDPNNNLQEGTDPETEDPNSLPPDHEVLDPEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN", "length": 396, "header": "tr|A0A8C2N588-1|A0A8C2N588_CRIGR Isoform 1 of Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Herpud1 PE=4 SV=1 CANONICAL=A0A8C2N588-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FMI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588/entry#A0A9J7FMI4-1", "sequence": { "sequence": "MEPEPQPEQVTLLVKSPNQRHRDLELSGDRSWSVSRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLPKEKRHVLHLVCNVKNPSKMLEAKTKGAESTEQPANTDQAQHPQAQHPGDSSGDGLRQREVLRNLSPSGWENISRPEAVQQAFQGLGPGFSGYTTYGWLQLSWFQQIYARQYYMQYLAATAASGAFVPTPSAQEIPVVSTPTPAPIHNQFPAENQPANQNAAAQVVVNPGANQNLRMNAQGGPLVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPDDGPPQEAANQDPNNNLQEGTDPETEDPNSLPPDHEVLDPEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN", "length": 395, "header": "tr|A0A9J7FMI4-1|A0A8C2N588_CRIGR Computationally mapped isoform of Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Herpud1 PE=4 SV=1 CANONICAL=A0A8C2N588-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 203, "start_aa": "Thr", "end_pos": 203, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr203", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 216, "start_aa": "Thr", "end_pos": 216, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr216", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FMI4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMI4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FMI4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMI4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758367", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758367", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BJ02-1", "protein_name": "Homocysteine inducible ER protein with ubiquitin like domain 1", "gene_name": "HERPUD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPEPEPVTLLVKSPNQRHRDLELSGDRSWSVGRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLPKQEKRHVLHLVCSVKSPSKIPEASTKVAESREQPAGLNQGPSPGDSSSDGLRQREVVRNPSPSGWENISRSDAAQLAFQGLGPGFSGYTTYGWLQLSWFQQMYARQYYMQYLAATAASGAFVPSPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGANQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLCILYFYSSLSRFLMVMGATIVMYLHHVGWFPFRQRPVQNLPNDGPPQEAVNQDPNNNFQEGPDPEIEDPNHLPPDRDVLDEEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN", "length": 389 }, "evidence": [ { "id": "A0A8C2N588", "url": "https://omabrowser.org/oma/group/A0A8C2N588/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6B3C5-1", "protein_name": "Homocysteine inducible ER protein with ubiquitin like domain 1", "gene_name": "Herpud1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQPRRVASARTLALSPPLRRLSPGADWATLGTDLCLSQWTAATESAICGILARGAHKRYPRRGRVSQRHQVSLWGRRRLRRRPFGIPERSRASSAADMEPEPQPEPVTLLVKSPNQRHRDLELSGDRGWSVSRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLQDLLPKQEKRHVLHLVCNVRSPSKKPEASTKGAESTEQPDNTSQAQYPGDSSSDGLREREVLRNLPPSGWENVSRPEAVQQTFQGLGPGFSGYTTYGWLQLSWFQQIYARQYYMQYLAATAASGAFGPTPSAQEIPVVSTPAPAPIHNQFPAENQPANQNAAAQAVVNPGANQNLRMNAQGGPLVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPDDGPPQEAANQDPNNNLQGGLDPEMEDPNRLPVGREVLDPEHTSPSFMSTAWLVFKTFFASLLPEGPPALAN", "length": 489 }, "evidence": [ { "id": "A0A8C2N588", "url": "https://omabrowser.org/oma/group/A0A8C2N588/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1A4S3-1", "protein_name": "Homocysteine inducible ER protein with ubiquitin like domain 1", "gene_name": "HERPUD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAEDLSLSLLVRSPARRHPDLRLRAAPAWSVRRLKAELRRRAPGAPAEEDQKLIYCGKLLLDHQLLREFLPGQEELHALHLVYNMRTPTDVPESSTEVKAAQPKHVTEASQEPAAASSGGGRLRCSPGGQAAAEADARPETPRHPFQAVPPGFSVYTTYSMLQMSWLQQIYARQYYMQYLASTAASADPSSTRRSSEIPVTPPAPLPDPFPAQNQPGDQNAAPQANVANQNLRMNAQGGPLMGEEEEGGNRDWLDWLYSATLFYVFVNIVYFYSSVSRFLLVMGGTVLMYLHHVGWFPFRQRRAQPFPDNVPPQAAVNQDQNNNLQQGGNAGRAEEPEALPDVGQVLPELPQVNPSLMSTAWLFFKTFFASLLPEGPRLTRN", "length": 382 }, "evidence": [ { "id": "A0A8C2N588", "url": "https://omabrowser.org/oma/group/A0A8C2N588/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q15011-1", "protein_name": "Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein", "gene_name": "HERPUD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESETEPEPVTLLVKSPNQRHRDLELSGDRGWSVGHLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLPKQEKRHVLHLVCNVKSPSKMPEINAKVAESTEEPAGSNRGQYPEDSSSDGLRQREVLRNLSSPGWENISRPEAAQQAFQGLGPGFSGYTPYGWLQLSWFQQIYARQYYMQYLAATAASGAFVPPPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGANQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRPRPVQNFPNDGPPPDVVNQDPNNNLQEGTDPETEDPNHLPPDRDVLDGEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN", "length": 391 }, "evidence": [ { "id": "A0A8C2N588", "url": "https://omabrowser.org/oma/group/A0A8C2N588/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JJK5-1", "protein_name": "Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein", "gene_name": "Herpud1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPEPQPEPVTLLVKSPNQRHRDLELSGDRSWSVSRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLQDLLPKQEKRHVLHLVCNVKNPSKMPETSTKGAESTEQPDNSNQTQHPGDSSSDGLRQREVLRNLSPSGWENISRPEAVQQTFQGLGPGFSGYTTYGWLQLSWFQQIYARQYYMQYLAATAASGTFVPTPSAQEIPVVSTPAPAPIHNQFPAENQPANQNAAAQAVVNPGANQNLRMNAQGGPLVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPDDGGPRDAANQDPNNNLQGGMDPEMEDPNRLPPDREVLDPEHTSPSFMSTAWLVFKTFFASLLPEGPPALAN", "length": 391 }, "evidence": [ { "id": "A0A8C2N588", "url": "https://omabrowser.org/oma/group/A0A8C2N588/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ], "pmid": "" }, { "name": "endoplasmic reticulum calcium ion homeostasis", "id": "GO:0032469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032469", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ], "pmid": "" }, { "name": "positive regulation of ERAD pathway", "id": "GO:1904294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904294", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ], "pmid": "" }, { "name": "protein targeting to ER", "id": "GO:0045047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045047", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ], "pmid": "" }, { "name": "negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway", "id": "GO:1902236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902236", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ], "pmid": "" }, { "name": "retrograde protein transport, ER to cytosol", "id": "GO:0030970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030970", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ], "pmid": "" }, { "name": "positive regulation of ubiquitin-dependent protein catabolic process", "id": "GO:2000060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000060", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ], "pmid": "" }, { "name": "regulation of ERAD pathway", "id": "GO:1904292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904292", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum quality control compartment", "id": "GO:0044322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044322", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ], "pmid": "" }, { "name": "Lewy body core", "id": "GO:1990037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990037", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ], "pmid": "" }, { "name": "Hrd1p ubiquitin ligase complex", "id": "GO:0000836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000836", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N588", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N588", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N588" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 72, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 203, 216 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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This record is derived from a genomic sequence (NW_003613936.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003503096.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003503096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503096" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5B7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rdh14", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B7", "locus": {} } ], "crossref": [ { "id": "100757118", "url": "https://www.ncbi.nlm.nih.gov/gene/100757118", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757118", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757118", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NTTWCAT", "url": "https://omabrowser.org/oma/group/NTTWCAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N5B7", "url": "https://www.orthodb.org/?gene=A0A8C2N5B7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43157", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43157", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43157:SF72", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43157:SF72", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003503096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503096", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "25033", "url": "https://www.rhea-db.org/rhea/25033", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54912", "url": "https://www.rhea-db.org/rhea/54912", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54916", "url": "https://www.rhea-db.org/rhea/54916", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N5B7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N5B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVATVAAALLAALGGALWLATRRFSGARGQRMQGGGDRSLMHGKTVLITGANSGLGRATASELLRLGARVIMGCRDRARAEEAAGQLRQELGRAAGQEPNATEGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYNKSFSYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLARPLFNLVSWAFFKTPQEGAQTSIYLASSPEVEGVSGRYFGDCKEEDLLPKAMDESVARKLWDISEVMVGILK", "length": 334, "header": "tr|A0A8C2N5B7-1|A0A8C2N5B7_CRIGR Isoform 1 of Retinol dehydrogenase 14 OS=Cricetulus griseus OX=10029 GN=Rdh14 PE=3 SV=1 CANONICAL=A0A8C2N5B7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N5B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B7/entry#A0A8C2N5B7-1", "sequence": { "sequence": "MAVATVAAALLAALGGALWLATRRFSGARGQRMQGGGDRSLMHGKTVLITGANSGLGRATASELLRLGARVIMGCRDRARAEEAAGQLRQELGRAAGQEPNATEGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYNKSFSYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLARPLFNLVSWAFFKTPQEGAQTSIYLASSPEVEGVSGRYFGDCKEEDLLPKAMDESVARKLWDISEVMVGILK", "length": 334, "header": "tr|A0A8C2N5B7-1|A0A8C2N5B7_CRIGR Isoform 1 of Retinol dehydrogenase 14 OS=Cricetulus griseus OX=10029 GN=Rdh14 PE=3 SV=1 CANONICAL=A0A8C2N5B7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5B7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5B7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757118", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757118", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZUY0-1", "protein_name": "Retinol dehydrogenase 14", "gene_name": "Rdh14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVASVAAALLAALGGALWLAARRFSGSSGQRRQGGGDPGLMHGKTVLITGANSGLGRATAGELLRLGARVIMGCRDRARAEEAAGQLRQELGQAGGLGPDATDGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGVFQCPYTKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYNKSFCYSRSKLANILFTRELAHRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLARPLFNLVSWAFFKTPLEGAQTSIYLASSPDVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGILK", "length": 334 }, "evidence": [ { "id": "A0A8C2N5B7", "url": "https://omabrowser.org/oma/group/A0A8C2N5B7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SCT9-1", "protein_name": "Retinol dehydrogenase 14", "gene_name": "RDH14", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVATVAAFLAALGGALWLAARRFVGPSVQRLHRGGDSGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQTEGPEEGPNSGGAGELVVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFAVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVRPLFNLVSWAFFKTPAEGAQTSVYLASSPEVEGVSGKYFGDCKEEELLPKAMDDSVARKLWDISEVMVGILK", "length": 336 }, "evidence": [ { "id": "A0A8C2N5B7", "url": "https://omabrowser.org/oma/group/A0A8C2N5B7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q17QW3-1", "protein_name": "Retinol dehydrogenase 14", "gene_name": "RDH14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAVGTAAALLAALGGILWLAARRFVGSSVQRLHQGRDSGLMRGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRERAEEAAGQLRREVCPAGGPDSGPNSGGAGELVVKELDLASLSSVRSFCQEMLQEEPRLDVLINNAGVFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTSVTVNVLHPGIVRTNLGRHIHIPLLVRPLFNLVSWAFFKTPEEGAQTAVYLASSPEVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGILK", "length": 336 }, "evidence": [ { "id": "A0A8C2N5B7", "url": "https://omabrowser.org/oma/group/A0A8C2N5B7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9ERI6-1", "protein_name": "Retinol dehydrogenase 14", "gene_name": "Rdh14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"UniProtKB", "id": "A0A8C2N5B7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5B7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "all-trans-retinol dehydrogenase (NADP+) activity", "id": "GO:0052650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052650", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5B7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "25033", "name": "", "equation": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8C2MVF9-1", "A0A9J7J7W0-1", "A0A8C2MM31-1", "A0A9J7EXN2-1", "A0A9J7F2T0-1", "A0A8C2N5B7-1", "A0A9J7GZC5-1", "A0A9J7G286-1", "A0A9J7GK21-1" ], "evidence": [ { "id": "25033", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25033" } ] }, { "id": "54912", "name": "", "equation": "11-cis-retinol + NADP(+) = 11-cis-retinal + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8C2N5B7-1" ], "evidence": [ { "id": "54912", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54912" } ] }, { "id": "54916", "name": "", "equation": "9-cis-retinol + NADP(+) = 9-cis-retinal + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8C2N5B7-1" ], "evidence": [ { "id": "54916", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54916" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8C2MM31", "gene_name": "LOC100771290", "activity": [ { "ec_number": "1.1.1.300", "activity": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+).", "evidence": [ { "id": "A0A8C2MM31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MM31" } ] }, { "ec_number": "1.1.1.184", "activity": "a secondary alcohol + NADP(+) = a ketone + NADPH + H(+).", "evidence": [ { "id": "A0A8C2MM31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MM31" } ] }, { "ec_number": "1.1.1.300", "activity": "", "evidence": [ { "id": "A0A8C2MM31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MM31" } ] }, { "ec_number": "1.1.1.184", "activity": "", "evidence": [ { "id": "A0A8C2MM31", 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Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5B9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770769", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770769", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5B9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B9" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5B9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B9" } ], "pmid": "" }, { "name": "cytoskeleton of presynaptic active zone", "id": "GO:0048788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048788", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5B9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of presynaptic active zone", "id": "GO:0098882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098882", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5B9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "neuromuscular synaptic transmission", "id": "GO:0007274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007274", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5B9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B9" } ], "pmid": "" }, { "name": "regulation of synaptic plasticity", "id": "GO:0048167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048167", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5B9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B9" } ], "pmid": "" }, { "name": "regulation of presynaptic cytosolic calcium ion concentration", "id": "GO:0099509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099509", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5B9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B9" } ], "pmid": "" }, { "name": "synaptic vesicle priming", "id": "GO:0016082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016082", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5B9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B9" } ], "pmid": "" }, { "name": "regulation of calcium-dependent activation of synaptic vesicle fusion", "id": "GO:0150037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150037", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5B9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5B9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N5E5-1", "uniprot_ac": "A0A8C2N5E5", "uniprot_id": "A0A8C2N5E5_CRIGR", "mass": { "chemical_mass": 63974.0, "monoisotopic_mass": 63974.0 }, "refseq": { "ac": "XP_003508272", "name": "TBCC domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508272" }, "gene_names": [ { "name": "Tbccd1", "type": "recommended", "evidence": [ { "id": "A0A8C2N5E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5E5" } ] }, { "name": "Tbccd1", "type": "synonym", "evidence": [ { "id": "XP_003508272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508272" } ] } ], "protein_names": [ { "name": "TBCC domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8C2N5E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5E5/entry#names_and_taxonomy" } ] }, { "name": "TBCC domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_003508272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508272" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614504.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003508272", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508272" } ] }, { "annotation": "Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5E5#function" }, { "database": "UniProtKB", "id": "ARBA00058452", "url": "https://www.uniprot.org/uniprotkb/ARBA00058452#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5E5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tbccd1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5E5", "locus": {} } ], "crossref": [ { "id": "100766911", "url": "https://www.ncbi.nlm.nih.gov/gene/100766911", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012945", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012945", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766911", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766911", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VPNAWDQ", "url": "https://omabrowser.org/oma/group/VPNAWDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N5E5", "url": "https://www.orthodb.org/?gene=A0A8C2N5E5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16052", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16052", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16052:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16052:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07986", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07986", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003508272", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508272", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N5E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N5E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5E5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQSRVFLWVKAEPFIVGALQVPPPSKFSLHYLRKIATYVRTRATEGAYPRLYWSTWRHIACGKLQLAKELAWLYFEIFDNLSVRTPEERLEWSEILSNCMTEDEVEKQRNQLSVDTLQFLLFLYIQQLNKISLRTSLIGEEWPSPRSRPQSPSLTERPSCHNKNWNDYSHQAFVCDHLLDLLELLLEPEQLTASFHSTHSSVVSREAVLALSFLIEGTVSRTRKVYPLHELAMWQPLHADSGFSKISKTFSFYKLEAWLRTCLTANPFGPSACLKSGKKLAWAHQVEGATKRAKIACNTHVAPQMHRMVVMSQVYKQTLAKSSDTLVGAHIRVHRCNESFIYLLSPLRSVTIEKCRNTTFVLGPVETALHLQDCENLKIIAVCHRLSISSTTDCTFHVMTPSRPLILSGNQSVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMVVCRESSDTRVFRLLPPCEFYIFIIPFEMEGDTAEIPGGLPSAYQKVLAQRERKIQIWQKTVKEARLTKEQRKQFQVLVENKFYEWLINTGHRQQLDSLVPHAAASKQEPG", "length": 557, "header": "tr|A0A8C2N5E5-1|A0A8C2N5E5_CRIGR Isoform 1 of TBCC domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Tbccd1 PE=3 SV=1 CANONICAL=A0A8C2N5E5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N5E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5E5/entry#A0A8C2N5E5-1", "sequence": { "sequence": "MDQSRVFLWVKAEPFIVGALQVPPPSKFSLHYLRKIATYVRTRATEGAYPRLYWSTWRHIACGKLQLAKELAWLYFEIFDNLSVRTPEERLEWSEILSNCMTEDEVEKQRNQLSVDTLQFLLFLYIQQLNKISLRTSLIGEEWPSPRSRPQSPSLTERPSCHNKNWNDYSHQAFVCDHLLDLLELLLEPEQLTASFHSTHSSVVSREAVLALSFLIEGTVSRTRKVYPLHELAMWQPLHADSGFSKISKTFSFYKLEAWLRTCLTANPFGPSACLKSGKKLAWAHQVEGATKRAKIACNTHVAPQMHRMVVMSQVYKQTLAKSSDTLVGAHIRVHRCNESFIYLLSPLRSVTIEKCRNTTFVLGPVETALHLQDCENLKIIAVCHRLSISSTTDCTFHVMTPSRPLILSGNQSVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMVVCRESSDTRVFRLLPPCEFYIFIIPFEMEGDTAEIPGGLPSAYQKVLAQRERKIQIWQKTVKEARLTKEQRKQFQVLVENKFYEWLINTGHRQQLDSLVPHAAASKQEPG", "length": 557, "header": "tr|A0A8C2N5E5-1|A0A8C2N5E5_CRIGR Isoform 1 of TBCC domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Tbccd1 PE=3 SV=1 CANONICAL=A0A8C2N5E5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5E5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5E5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766911", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766911", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480MDB5-1", "protein_name": "TBCC domain-containing protein 1", "gene_name": "TBCCD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQSGVLLWVKAEPFIVGALQVPPPSKFSLHYLRKISSYVRTRATEGGYPRLSWSTWRHIACGKLQLAKDLAWLYFEIFDSLTVKTPEERLEWSEILSNCMSGDEVEKQRNQLSVDTLQFLLFLYIQQLNKVSLRTSLIGEEWPSPRHRSQSPDLTEKSSCHNKNWNDYSHQAFVCDHLSDLLELLLDPEQLTASFHSTHSSLVSREAVVALSFLIEGTVSGARKIYPLYELALWQPLHAETGFSKTSKAFSFYKLEAWLRASLTGNPFGTSACLKSGKKLAWAHQVEGTTKRAKIACNTHVAPRMYRMVVMSQVYKQTLAKSSDTLVGAHVKIHRCNESFIYLLSPLRSVTVEKCRNSTFVLGPVQTALHLHSCDNVKVIAVCHRLSISSTTDCIFHILTPTRPLILSGNQRVTFAPFHTHYPMLEDHMARTGLAAVPNYWDNPMIVCRENSNTSVFRLLPPCDFYVFIIPFEMEGDTTEIPGGLPSAYQRALGQREKKIQIWQKTVKEARLTKDQRKQFQVLVENKFYEWLINTGHRQQLDSLVPPTVGSKQAAG", "length": 557 }, "evidence": [ { "id": "A0A8C2N5E5", "url": "https://omabrowser.org/oma/group/A0A8C2N5E5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A4QP31-1", "protein_name": "TBCC domain-containing protein 1", "gene_name": "tbccd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDKYTAYVWPRLEPFLVGVLPATPPSKFSMHYLRKMASYVRTRDGCFPRLGWQMWRHIACGKLQLAEDLAWLYFETFDLLMPRSAEQRLEWAEALSQCHTQKELDRQRCKLSVDTLQFLLFLYLQQLNRISLRTSLIGEEWPSPRSRSPSSSSSERDAKISSQNKNWDVQAHLTFIQTHLPELLELLVEPGQLSSSGQVLRDSHLTSEAVESLSLLLEGSVSHSRTVHPVHKLLSRSQLQSQAGFSKLSCSYSLQQFQDFLRQALCLNPFGISNCSQSGKKLSWALQVEGTLKKAKIFRNTHAAPPGSRLVLMSQVCKQTLAKDSEKLNDVNIKLHRCSEAFIYLLSPLWSVTLDKCRNSTLVLGPVRTSVHIQSCENVRVVCVAGRLTIGGSFNCTIHSLTPTRPLLLPGNASLTLGPFHTQYPTLEDHMASAGLAVVPNLWNQPLLFGVEGSAPDTGCYRIQPPSEFYPLVIPFQMDGDNCEIPCSLPEDFQKALESREKTIEEWQKTVKDAHLNKAQRRQFQALVEQKFHEWLLETGQRQELDSLLPPTITPSSSAEHWSSNQNTLKEQTHEQPTGTVC", "length": 582 }, "evidence": [ { "id": "A0A8C2N5E5", "url": "https://omabrowser.org/oma/group/A0A8C2N5E5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5FVR8-1", "protein_name": "TBCC domain-containing protein 1", "gene_name": "Tbccd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQSGVLLWVKAEPFIVGALQEPPPSKLSLHYLKKVAAYVRTRATERAYPRLYWPTWRHIACGKLQLAKDLAWLYFEIFDNLSERTPEERLEWSEILSNCTTKDEVEKQRNQLSVDTLQFLLFLYIQQLNKISLRTSFIGEEWPSPRNRPKSPSPAERSSCHNKNWNDYNHQAFVCDHLSELLELLLDPEQLTESFHSTQSSLLSREAVTALSFLIEGTVSRTKKVYPLHELALWQPLHAANGFSKISKTFSLYKLEAWLRACLTTNPFGLSACLQSGKKLAWAHKVEGATKRAKIACNAHMAPRSHRIVVMSQVCNQTLAKSSETLVGAHVRAHRCNESFIYLLSPLRSMTIEKCRNSTFVLGPVETALHLHGCENLKVIAVCHRLSVSSTIGCTFHIMTPSRPLILSGNQTVTFAPFHTHYPMLEDHMARTGLATVPNYWDDPMVLGGEGTDTRVFQLLPPSEFYVFVTPFEMEGDTAEIPGGLPPAYQKALAHREQRIHNWQKTVKEARLTKEQRKQFQVLVENKFYEWLVSTGHRQQLDSLVPPPAASNQVAKKDLTWSHGALET", "length": 569 }, "evidence": [ { "id": "A0A8C2N5E5", "url": "https://omabrowser.org/oma/group/A0A8C2N5E5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5ZKT1-1", "protein_name": "TBCC domain-containing protein 1", "gene_name": "TBCCD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAVSLWPRTEPLLLGALPVPPPARLGPHYLRKMAAYARARAAEGCYPRLSWPRWRHIACGKLQLGRGLAWLYFERFHDLLPPPDPPRRLQRAEAEAACGSAEELERERGKLSVDTLRFLLFLYLQQLNKASLRTSLIGEEWPSHRARAAGLPGRAAGQSKNWNDQDHLAFLLTHLSDMLELLLEPEQLGASSHATHNSLVSYEAVCALSFLIEGTVNNSRTIHPLHELALWQPCHGQNGYSKISKTFSFPKLENWLRSCLIINPFGMTACLRSGKKLAWAQQVEGTTRRAKIACNTRVVPEVSPMVIMSQVYKQTLAKSSDTLVGAHVRIHRCNESFIYLLSPLCSVTIEKCRNSTFVLGPVEASVHVHSCDNIKVITVCHCLSLSSTTGCTFHILTPTQPLILAGNQAISFAPFHTHYPMLEDHMAQVGLATVPNYWDSPMMVCKEGSDASVFRLLSPLDFYTFVIPFEMEGDTTETPGGLPHAYQKALNQREQKVQIWQKMVKEACLTKDQRKQFQMLVESKFYEWLIQTGNRQQLDSLVPPAVGSKQAAG", "length": 555 }, "evidence": [ { "id": "A0A8C2N5E5", "url": "https://omabrowser.org/oma/group/A0A8C2N5E5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q640P7-1", "protein_name": "TBCC domain-containing protein 1", "gene_name": "Tbccd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQSGVLLWVKAEPFLVGALQEPPPSKFSLHYLRKIATYVRTRATEGAYPHLYWPTWRHIACGKLQLAKDLAWLYFEMFDNLSVRTPEERLEWSEILSNCATEEEVEKQRSQLYVDTLQFLLFLYIQQLNRISLRTSLIGEEWPSRRSRPQSPSPAERPSCHNKNWNDYSHQAFVCNHLSELLELLLDPEQLTASFHSTHSSLLSRDAVTALSFLIEGTVSRAKKVYPLHQLALWQPLHVASGFSKSSKTFSLYKLEAWLRASLTTNPFGPSACLKSGKKLAWAHQVEGSTKRAKIACNAHMAPRLHRIVVMSQVYKQTLAKSSETLVGAHVRAHRCSESFIYLLSPLRSMTIEKCRNSTFVLGPVETTLHLHDCENLKVIAVCHRLSISSTTSCTFHIMTPSRPLILSGNQTVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMVVCKEGSVTSLFRLLPPSEFYIFVIPFEMEGDTAEIPGGLPSAYQKALAQREESIHIWQKTVKEARLTKEQRKQFQALVENKFYEWLVSTGHRQQLDSLVPTPAAS", "length": 552 }, "evidence": [ { "id": "A0A8C2N5E5", "url": "https://omabrowser.org/oma/group/A0A8C2N5E5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVR7-1", "protein_name": "TBCC domain-containing protein 1", "gene_name": "TBCCD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDQSRVLLWVKAEPFIVGALQVPPPSKFSLHYLRKISTYVQIRATEGAYPRLYWSTWRHIACGKLQLAKDLAWLYFEIFDSLSMKTPEERLEWSEVLSNCMSEEEVEKQRNQLSVDTLQFLLFLYIQQLNKVSLRTSLIGEEWPSPRNKSQSPDLTEKSNCHNKNWNDYSHQAFVYDHLSDLLELLLDPKQLTASFHSTHSSLVSREAVVALSFLIEGTISRARKIYPLHELALWQPLHADSGFSKISKTFSFYKLETWLRSCLTGNPFGTSACLKSGKKLAWAHQVEGTTKRAKIACNTHVAPRMHRLVVMSQVYKQTLAKSSDTLAGAHVKIHRCNESFIYLLSPLRSVTIEKCRNSIFVLGPVGTTLHLHSCDNVKVIAVCHRLSISSTTGCIFHVLTPTRPLILSGNQTVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMVVCRENSDTRVFQLLPPCEFYVFIIPFEMEGDTTEIPGGLPSVYQKALGQREQKIQIWQKTVKEAHLTKDQRKQFQVLVENKFYEWLINTGHRQQLDSLVPPAAGSKQAAG", "length": 557 }, "evidence": [ { "id": "A0A8C2N5E5", "url": "https://omabrowser.org/oma/group/A0A8C2N5E5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "maintenance of Golgi location", "id": "GO:0051684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051684", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5E5" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5E5" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5E5" } ], "pmid": "" }, { "name": "maintenance of centrosome location", "id": "GO:0051661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051661", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5E5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "spindle pole centrosome", "id": "GO:0031616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031616", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5E5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5E5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N5E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5E5" }, { "id": "PS51329", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51329" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-CAP/cofactor C-like", "eco_id": "ECO_0000259", "start_pos": 303, "end_pos": 435, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 338, "end_pos": 340 }, { "start_pos": 358, "end_pos": 360 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N5J5-1", "uniprot_ac": "A0A8C2N5J5", "uniprot_id": "A0A8C2N5J5_CRIGR", "mass": { "chemical_mass": 61433.0, "monoisotopic_mass": 61433.0 }, "refseq": { "ac": "XP_027277936", "name": "EH domain-containing protein 4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277936" }, "gene_names": [ { "name": "Ehd4", "type": "recommended", "evidence": [ { "id": "A0A8C2N5J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5J5" } ] }, { "name": "Ehd4", "type": "synonym", "evidence": [ { "id": "XP_027277936", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277936" } ] } ], "protein_names": [ { "name": "EH domain-containing protein 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027277936", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277936" }, { "id": "A0A8C2N5J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5J5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027277936", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277936" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5J5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5J5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ehd4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5J5", "locus": {} } ], "crossref": [ { "id": "cd00052", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00052", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09913", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09913", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771177", "url": "https://www.ncbi.nlm.nih.gov/gene/100771177", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031692", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031692", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771177", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771177", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N5J5", "url": "https://www.orthodb.org/?gene=A0A8C2N5J5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11216", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11216", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11216:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11216:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00350", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00350", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16880", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16880", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18150", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18150", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027277936", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277936", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N5J5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N5J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5J5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSWMGRQAGGRERSGGMDAVQTVTGGLRSLYQRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPNVFGKENKKRELIFRLPEIYVQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKIASLMSLISQEEMNMPTQMVQGGAFDGTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPNSLPPHLVPPSHRKSLPKAD", "length": 541, "header": "tr|A0A8C2N5J5-1|A0A8C2N5J5_CRIGR Isoform 1 of EH domain-containing protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ehd4 PE=4 SV=1 CANONICAL=A0A8C2N5J5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N5J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5J5/entry#A0A8C2N5J5-1", "sequence": { "sequence": "MFSWMGRQAGGRERSGGMDAVQTVTGGLRSLYQRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPNVFGKENKKRELIFRLPEIYVQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKIASLMSLISQEEMNMPTQMVQGGAFDGTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPNSLPPHLVPPSHRKSLPKAD", "length": 541, "header": "tr|A0A8C2N5J5-1|A0A8C2N5J5_CRIGR Isoform 1 of EH domain-containing protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ehd4 PE=4 SV=1 CANONICAL=A0A8C2N5J5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5J5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5J5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"https://www.uniprot.org/uniprotkb/A0A8C2N5J5" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5J5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5J5" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5J5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5J5" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5J5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5J5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { 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}, { "name": "tripartite motif-containing protein 44 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007610758", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007610758" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 772 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280487", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280487" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N5Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5Z5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Grhl1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N5Z5", "locus": {} } ], "crossref": [ { "id": "100753443", "url": "https://www.ncbi.nlm.nih.gov/gene/100753443", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007604", "database": "InterPro", "categories": [ "Protein Classification" ] 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Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614112.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003505074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505074" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N686", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ptp4a1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686", "locus": {} } ], "crossref": [ { "id": "cd18537", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18537", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100763215", "url": "https://www.ncbi.nlm.nih.gov/gene/100763215", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763215", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763215", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IQVHGWT", "url": "https://omabrowser.org/oma/group/IQVHGWT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N686", "url": "https://www.orthodb.org/?gene=A0A8C2N686", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22785", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22785", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003505074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505074", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N686", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N686-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIRVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ", "length": 173, "header": "tr|A0A8C2N686-1|A0A8C2N686_CRIGR Isoform 1 of protein-tyrosine-phosphatase OS=Cricetulus griseus OX=10029 GN=Ptp4a1 PE=3 SV=1 CANONICAL=A0A8C2N686-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N686-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686/entry#A0A8C2N686-1", "sequence": { "sequence": "MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIRVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ", "length": 173, "header": "tr|A0A8C2N686-1|A0A8C2N686_CRIGR Isoform 1 of protein-tyrosine-phosphatase OS=Cricetulus griseus OX=10029 GN=Ptp4a1 PE=3 SV=1 CANONICAL=A0A8C2N686-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3H060-1", "G3H622-1", "G3H9Q0-1", "A0A8C2LH05-1", "G3HKY7-1", "G3GWQ6-1", "G3HBF6-1", "G3GRD1-1", "G3H8H2-1", "A0A9J7FG56-1", "A0A061IAM9-1", "A0A9J7GE78-1", "A0A9J7GZK0-1", "A0A061HX98-1", "A0A061HZS8-1", "A0A3L7HEJ5-1", "A0A8C2LYZ8-1", "A0A9J7JC04-1", "A0A8C2MQ28-1", "A0A3L7I231-1", "A0A9J7EY47-1", "A0A8C2LVB9-1", "A0A8C2MZ43-1", "A0A9J7G003-1", "A0A8C2QC02-1", "A0A9J7JD11-1", "A0A8C2QH88-1", "A0A9J7EXY7-1", "A0A9J7JC62-1", "A0A9J7FEN1-1", "A0A9J7FB56-1", "A0A9J7FEZ5-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FWX7-1", "A0A9J7G1A0-1", "A0A9J7JTT7-1", "A0A9J7G7L1-1", "A0A9J7G7K2-1", "A0A9J7GNR2-1", "A0A9J7JU39-1", "A0A9J7KAX8-1", "A0A9J7GQG9-1", "A0A9J7GX92-1", "A0A9J7F2A0-1", "A0A9J7EZC9-1", "A0A9J7EZL1-1", "A0A9J7FIV0-1", "A0A8C2MFV5-1", "A0A8C2N2E5-1", "A0A8C2N686-1", "A0A8C2QCP2-1", "A0A3L7IA07-1", "A0A9J7FYL8-1", "A0A9J7G168-1", "A0A9J7GBQ5-1", "A0A9J7H7L7-1", "A0A9J7HBK7-1", "A0A9J7GQC8-1", "A0A9J7H152-1", "A0A9J7KDA7-1", "A0A9J7KDM0-1", "A0A9J7J766-1", "A0A9J7FKB3-1", "A0A3L7HAL2-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HX98", "gene_name": "Dusp9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] } ] }, { "uniprot_ac": "A0A061HZS8", "gene_name": "Ptpn14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HZS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZS8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HZS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZS8" } ] } ] }, { "uniprot_ac": "A0A061IAM9", "gene_name": "LOC100766206", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] } ] }, { "uniprot_ac": "A0A3L7HAL2", "gene_name": "Pgp", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] } ] }, { "uniprot_ac": "A0A3L7HEJ5", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] } ] }, { "uniprot_ac": "A0A3L7I231", "gene_name": "Ptp4a3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] } ] }, { "uniprot_ac": "A0A3L7IA07", "gene_name": "Ptp4a2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] } ] }, { "uniprot_ac": "A0A8C2LH05", "gene_name": "Acp1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] } ] }, { "uniprot_ac": "A0A8C2LVB9", "gene_name": "Dusp22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] } ] }, { "uniprot_ac": "A0A8C2LYZ8", "gene_name": "Ptprf", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] } ] }, { "uniprot_ac": "A0A8C2MFV5", "gene_name": "LOC100758361", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] } ] }, { "uniprot_ac": "A0A8C2MQ28", "gene_name": "Ptprz1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] } ] }, { "uniprot_ac": "A0A8C2MZ43", "gene_name": "Ptprg", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] } ] }, { "uniprot_ac": "A0A8C2N2E5", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] } ] }, { "uniprot_ac": "A0A8C2N686", "gene_name": "Ptp4a1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ] } ] }, { "uniprot_ac": "A0A8C2QC02", "gene_name": "Ptpn6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] } ] }, { "uniprot_ac": "A0A8C2QCP2", "gene_name": "Dusp28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] } ] }, { "uniprot_ac": "A0A8C2QH88", "gene_name": "Dusp12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] } ] }, { "uniprot_ac": "A0A9J7EXY7", "gene_name": "Ptpn13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] } ] }, { "uniprot_ac": "A0A9J7EY47", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] } ] }, { "uniprot_ac": "A0A9J7EZC9", "gene_name": "Ptpn18", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] } ] }, { "uniprot_ac": "A0A9J7EZL1", "gene_name": "LOC113830718", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] } ] }, { "uniprot_ac": "A0A9J7F2A0", "gene_name": "Ptpn12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7F2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2A0" } ] } ] }, { "uniprot_ac": "A0A9J7FB56", "gene_name": "Ptpru", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FB56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FB56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB56" } ] } ] }, { "uniprot_ac": "A0A9J7FEN1", "gene_name": "Eya1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] } ] }, { "uniprot_ac": "A0A9J7FEZ5", "gene_name": "Ptpn2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] } ] }, { "uniprot_ac": "A0A9J7FG56", "gene_name": "Cdc25c", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] } ] }, { "uniprot_ac": "A0A9J7FIV0", "gene_name": "LOC100763249", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] } ] }, { "uniprot_ac": "A0A9J7FKB3", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] } ] }, { "uniprot_ac": "A0A9J7FMB0", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] } ] }, { "uniprot_ac": "A0A9J7FWJ6", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FWX7", "gene_name": "LOC103158664", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] } ] }, { "uniprot_ac": "A0A9J7FYL8", "gene_name": "Ptpn11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] } ] }, { "uniprot_ac": "A0A9J7G003", "gene_name": "Ptprs", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G003" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G003" } ] } ] }, { "uniprot_ac": "A0A9J7G168", "gene_name": "LOC100762307", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ] } ] }, { "uniprot_ac": "A0A9J7G1A0", "gene_name": "Ptpn4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] } ] }, { "uniprot_ac": "A0A9J7G7K2", "gene_name": "Ptpn1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] } ] }, { "uniprot_ac": "A0A9J7G7L1", "gene_name": "Ptprj", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] } ] }, { "uniprot_ac": "A0A9J7GBQ5", "gene_name": "LOC100764354", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ5" } ] } ] }, { "uniprot_ac": "A0A9J7GE78", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] } ] }, { "uniprot_ac": "A0A9J7GNR2", "gene_name": "Ptpn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNR2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNR2" } ] } ] }, { "uniprot_ac": "A0A9J7GQC8", "gene_name": "LOC100757114", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GQC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQC8" } ] } ] }, { "uniprot_ac": "A0A9J7GQG9", "gene_name": "Ptprd", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] } ] }, { "uniprot_ac": "A0A9J7GX92", "gene_name": "Ptpre", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX92" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX92" } ] } ] }, { "uniprot_ac": "A0A9J7GZK0", "gene_name": "Ptprc", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZK0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZK0" } ] } ] }, { "uniprot_ac": "A0A9J7H152", "gene_name": "Ptprt", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H152" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7H152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H152" } ] } ] }, { "uniprot_ac": "A0A9J7H7L7", "gene_name": "Ptprh", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + 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"A0A9J7JZ39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZ39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZ39-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZ39-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAPSALPLLLLLACSWAPGGANLSQDGYWQEQELELGTLAPLDEALSSTVWSSPDMLASQDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVSSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKETATLNCQSSGSKPAAQLTWRKGDQELHGDQTRVQEDPNGKTFTVSSSVSFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTALIRPEPAHPREGQKLLLHCEGHGNPVPQQYLWVKEGSEPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYTAYFTLNVNDPSPVPSSSSTYHAIIGGIVAFIVFLLLILLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI", "length": 430, "header": "tr|A0A8C2N8B7-1|A0A8C2N8B7_CRIGR Isoform 1 of Cell adhesion molecule 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Cadm3 PE=3 SV=1 CANONICAL=A0A8C2N8B7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N687-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N8B7/entry#A0A8C2N687-1", "sequence": { "sequence": "MGAPSALPLLLLLACSWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVSSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKETATLNCQSSGSKPAAQLTWRKGDQELHGDQTRVQEDPNGKTFTVSSSVSFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTALIRPEPAHPREGQKLLLHCEGHGNPVPQQYLWVKEGSEPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYTAYFTLNVNDPSPVPSSSSTYHAIIGGIVAFIVFLLLILLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI", "length": 396, "header": "tr|A0A8C2N687-1|A0A8C2N8B7_CRIGR Computationally mapped isoform of Cell adhesion molecule 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Cadm3 PE=3 SV=1 CANONICAL=A0A8C2N8B7-1" }, "locus": {} }, { "isoform_ac": "A0A8C2N8B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N8B7/entry#A0A8C2N8B7-1", "sequence": { "sequence": "MGAPSALPLLLLLACSWAPGGANLSQDGYWQEQELELGTLAPLDEALSSTVWSSPDMLASQDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVSSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKETATLNCQSSGSKPAAQLTWRKGDQELHGDQTRVQEDPNGKTFTVSSSVSFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTALIRPEPAHPREGQKLLLHCEGHGNPVPQQYLWVKEGSEPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYTAYFTLNVNDPSPVPSSSSTYHAIIGGIVAFIVFLLLILLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI", "length": 430, "header": "tr|A0A8C2N8B7-1|A0A8C2N8B7_CRIGR Isoform 1 of Cell adhesion molecule 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Cadm3 PE=3 SV=1 CANONICAL=A0A8C2N8B7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JZ39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N8B7/entry#A0A9J7JZ39-1", "sequence": { "sequence": "MGAPSALPLLLLLACSWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVSSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKETATLNCQSSGSKPAAQLTWRKGDQELHGDQTRVQEDPNDTPTALIRPEPAHPREGQKLLLHCEGHGNPVPQQYLWVKEGSEPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYTAYFTLNVNDPSPVPSSSSTYHAIIGGIVAFIVFLLLILLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI", "length": 350, "header": "tr|A0A9J7JZ39-1|A0A8C2N8B7_CRIGR Computationally mapped isoform of Cell adhesion molecule 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Cadm3 PE=3 SV=1 CANONICAL=A0A8C2N8B7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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[], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 23, "end_pos": 25 }, { "start_pos": 322, "end_pos": 324 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N699-1", "uniprot_ac": "A0A8C2N699", "uniprot_id": "A0A8C2N699_CRIGR", "mass": { "chemical_mass": 23919.0, "monoisotopic_mass": 23919.0 }, "refseq": { "ac": "XP_035300573", "name": "ropporin-1A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300573" }, "gene_names": [ { "name": "Ropn1", "type": "recommended", "evidence": [ { "id": "A0A8C2N699", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N699" } ] }, { "name": "Ropn1", "type": "synonym", "evidence": [ { "id": "XP_035300573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300573" } ] } ], "protein_names": [ { "name": "Ropporin-1A", "type": "synonym", "evidence": [ { "id": "A0A8C2N699", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N699/entry#names_and_taxonomy" } ] }, { "name": "ropporin-1A", "type": "synonym", "evidence": [ { "id": "XP_035300573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300573" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035300573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300573" } ] }, { "annotation": "Important for male fertility. 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"database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4KLL5-1", "protein_name": "Ropporin-1", "gene_name": "Ropn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQTDKQVCIPPELPELLKQFTKAAIRTQPPDLIQWAAEYFGAMSRGEIPPVRERSEQVPLSNWAELTPELLKVLHSRVGGRLIIHADELAQMWKVLNLPTDLFNSVMNVGRFTEEIEWLKFLALACSSLGVTIAKTLKIVCEVLSCDHDGGPPRIPFSTFQFLYTYIAEVDGEISSSHVTRMLNYIEQEVIGPDGLIKVNDFTQNPRVRLE", "length": 212 }, "evidence": [ { "id": "A0A8C2N699", "url": "https://omabrowser.org/oma/group/A0A8C2N699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BZX4-1", "protein_name": "Ropporin-1B", "gene_name": "ROPN1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQTDKPTCIPPELPKMLKEFAKAAIRAQPQDLIQWGADYFEALSRGETPPVRERSERVALCNWAELTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRFTEEIEWLKFLALACSALGVTITKTLKIVCEVLSCDHNGGLPRIPFSTFQFLYTYIAEVDGEICASHVSRMLNYIEQEVIGPDGLITVNDFTQNPRVWLE", "length": 212 }, "evidence": [ { "id": "A0A8C2N699", "url": "https://omabrowser.org/oma/group/A0A8C2N699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ESG2-1", "protein_name": "Ropporin-1", "gene_name": "Ropn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPQTDKQVCIPPELPELLKQFTKDAIRTQPPDLIQWAAEYFGAMSRGEIPPVRERSEQIPLSNWAELTPELLKVLHSRVAGRLIIHADELAQMWKVLNLPTDLFNSVMNVGRFTEEIEWLKFLALACSSLGVTIAKTLKIVCEVLSSDHDGGPPRIPFSTFQFLYTYIAEVDGEISSSHVSRMLNYIEQEVIGPDGLIKVNDFTQNPRVRLE", "length": 212 }, "evidence": [ { "id": "A0A8C2N699", "url": "https://omabrowser.org/oma/group/A0A8C2N699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { 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"UniProtKB", "id": "A0A8C2N699", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N699" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N6A1-1", "uniprot_ac": "A0A8C2N6A1", "uniprot_id": "A0A8C2N6A1_CRIGR", "mass": { "chemical_mass": 27764.0, "monoisotopic_mass": 27764.0 }, "refseq": { "ac": "XP_027280493", "name": "14-3-3 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Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280493" } ] }, { "annotation": "Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6A1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6A1#function" }, { "database": "UniProtKB", "id": "ARBA00025150", "url": "https://www.uniprot.org/uniprotkb/ARBA00025150#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6A1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6A1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ywhaq", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6A1", "locus": {} } ], "crossref": [ { "id": "cd10023", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10023", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751694", "url": "https://www.ncbi.nlm.nih.gov/gene/100751694", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000308", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000308", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751694", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751694", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N6A1", "url": "https://www.orthodb.org/?gene=A0A8C2N6A1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280493", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N6A1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N6A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6A1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN", "length": 245, "header": "tr|A0A8C2N6A1-1|A0A8C2N6A1_CRIGR Isoform 1 of 14-3-3 protein theta OS=Cricetulus griseus OX=10029 GN=Ywhaq PE=3 SV=1 CANONICAL=A0A8C2N6A1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N6A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6A1/entry#A0A8C2N6A1-1", "sequence": { "sequence": "MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN", "length": 245, "header": "tr|A0A8C2N6A1-1|A0A8C2N6A1_CRIGR Isoform 1 of 14-3-3 protein theta OS=Cricetulus griseus OX=10029 GN=Ywhaq PE=3 SV=1 CANONICAL=A0A8C2N6A1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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] }, { "uniprot_canonical_ac": "A0A8C2N6F2-1", "uniprot_ac": "A0A8C2N6F2", "uniprot_id": "A0A8C2N6F2_CRIGR", "mass": { "chemical_mass": 18336.0, "monoisotopic_mass": 18336.0 }, "refseq": { "ac": "XP_003502353", "name": "beta-defensin 129", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502353" }, "gene_names": [ { "name": "Defb129", "type": "recommended", "evidence": [ { "id": "A0A8C2N6F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6F2" } ] }, { "name": "Defb129", "type": "synonym", "evidence": [ { "id": "XP_003502353", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502353" } ] } ], "protein_names": [ { "name": "Beta-defensin", "type": "recommended", "evidence": [ { "id": "A0A8C2N6F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6F2/entry#names_and_taxonomy" } ] }, { "name": "beta-defensin 129", "type": "synonym", "evidence": [ { "id": "XP_003502353", "database": "RefSeq", "url": 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This record is derived from a genomic sequence (NW_003613890.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502353", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502353" } ] }, { "annotation": "Has antibacterial activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6F2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6F2#function" }, { "database": "UniProtKB", "id": "RU231113", "url": "https://www.uniprot.org/uniprotkb/RU231113#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6F2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6F2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Defb129", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6F2", "locus": {} } ], "crossref": [ { "id": "100750561", "url": "https://www.ncbi.nlm.nih.gov/gene/100750561", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750561", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750561", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RRCLMGF", "url": "https://omabrowser.org/oma/group/RRCLMGF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N6F2", "url": "https://www.orthodb.org/?gene=A0A8C2N6F2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF13841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502353", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502353", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N6F2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6F2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N6F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6F2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLLFPLIASLMLQYQVKPAFVGMKKCILGFGKCKDSCLAKEIEVQNCKSKKCCIGPKVTELIKSYLRHEIPHIPDKDIVEMLKNEKNFREEMQRKHTLAALFQPQDASPSHGINSAIVPNTSPVKFVTSRTRRHGLDGTVSTKRHMKPIRSSASAAPQPGPGPS", "length": 165, "header": "tr|A0A8C2N6F2-1|A0A8C2N6F2_CRIGR Isoform 1 of Beta-defensin OS=Cricetulus griseus OX=10029 GN=Defb129 PE=3 SV=1 CANONICAL=A0A8C2N6F2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N6F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6F2/entry#A0A8C2N6F2-1", "sequence": { "sequence": "MKLLFPLIASLMLQYQVKPAFVGMKKCILGFGKCKDSCLAKEIEVQNCKSKKCCIGPKVTELIKSYLRHEIPHIPDKDIVEMLKNEKNFREEMQRKHTLAALFQPQDASPSHGINSAIVPNTSPVKFVTSRTRRHGLDGTVSTKRHMKPIRSSASAAPQPGPGPS", "length": 165, "header": "tr|A0A8C2N6F2-1|A0A8C2N6F2_CRIGR Isoform 1 of Beta-defensin OS=Cricetulus griseus OX=10029 GN=Defb129 PE=3 SV=1 CANONICAL=A0A8C2N6F2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027246041", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246041" } ] }, { "annotation": "Regulator of cell proliferation and apoptosis. It likely functions as a substrate-adapter that recruits key substrates, e.g. MSI2, to CUL3-based ubiquitin ligase complexes for degradation. Required for MSI2 ubiquitination and degradation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3#function" }, { "database": "UniProtKB", "id": "ARBA00093283", "url": "https://www.uniprot.org/uniprotkb/ARBA00093283#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rhobtb2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3", "locus": {} } ], "crossref": [ { "id": "cd01873", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01873", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18359", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18359", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18531", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18531", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770205", "url": "https://www.ncbi.nlm.nih.gov/gene/100770205", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770205", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770205", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TIDKDCN", "url": "https://omabrowser.org/oma/group/TIDKDCN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N6K3", "url": "https://www.orthodb.org/?gene=A0A8C2N6K3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24072", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24072", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027246041", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246041", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N6K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N6K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEEELGGPSGPGGPRPEDHRSHPEQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTFKSRLMVVVKMDNSIQPGPFRAVLKYLYTGELGENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIVLANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLRRQPKRRWLFWNSPSSPSSSAAGSASPSSSSAVV", "length": 727, "header": "tr|A0A8C2N6K3-1|A0A8C2N6K3_CRIGR Isoform 1 of Rho-related BTB domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Rhobtb2 PE=3 SV=1 CANONICAL=A0A8C2N6K3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N6K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3/entry#A0A8C2N6K3-1", "sequence": { "sequence": "MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEEELGGPSGPGGPRPEDHRSHPEQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTFKSRLMVVVKMDNSIQPGPFRAVLKYLYTGELGENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIVLANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLRRQPKRRWLFWNSPSSPSSSAAGSASPSSSSAVV", "length": 727, "header": "tr|A0A8C2N6K3-1|A0A8C2N6K3_CRIGR Isoform 1 of Rho-related BTB domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Rhobtb2 PE=3 SV=1 CANONICAL=A0A8C2N6K3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770205", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770205", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "M9PG08-1", "protein_name": "Rho-related BTB domain containing, isoform B", "gene_name": "RhoBTB", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPKMDNEQPHQELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVSLRLWDTFGDHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGCKNDLRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKELGVAYYETSVFTYFGVNEVFENAIRSALIARRQQRFWMTNLKKVQKPLLQAPFRPPKPPPPEVTVMVGNYRQDIYNMFLSQAYTDLVLVGAGGTKFAVHRFMLAAASSIFQRLLSTELTDMGGRSSSESSMVSSTFGEATIADFNDDTEALIRYESRTQRMWEHLKRRSSYQALPLMESKRSNDLYRELHHPVLQSIRLVHVENHRGVNGLQTIVTLSKLISPQALHQCLRFIYTGTIDKDCDNIEEIREAADLLELPQLTQLLSRPQTVMENSSDEPNPHICLRIKESMERHCIGDGCFSDVTFELDDGLMKAHRAVLVGRCDVMRAMLLGDFREAHSNVIVFPGVTIYTFHKLLCYLYTDQIPPISAVKCLNLLELANRLCLPRLLNLVECRVIEDLTLISQNETNETVDHCLKLLEPVKLHNAHQLAEWCMSYLCVNYNLICKFSLKGLKALHQDNQEYLREHRWPPVWYLKDYDYYQRCLNELNKELKLKTSRRESPSDDEGCLCFTGVFSCWLLGKSKRSADVSGTTDNSNADNQIFNSAGNSLNHIDLEADMDLNLXHPALGQGRSLRFIVILPVLICFICTILSILILFQIHT", "length": 783 }, "evidence": [ { "id": "A0A8C2N6K3", "url": "https://omabrowser.org/oma/group/A0A8C2N6K3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P34147-1", "protein_name": "Rho-related protein racA", "gene_name": "racA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MQAIKLVVVGDGAVGKSCLLIAYTTNAFPGEYVPTVFDNYSANVMIDGKPFNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSIVSRASFENIRAKWYPEILHHAPNIPIVLVGTKNDLRGHHDLKRPEVSAAEANNLVRELGFSGYVETSALLQTNLRELFSLAIRTATSPKSASAKKKGGFFSSSSSSSSSSSSKSSEKSVPIPPVMPPAGKAPWIDIITSSYDKEMRETLNSESFSDVKFTFFEERPVYAHRVILCSASEFFRRVFGYTLSSDQAEFKLDDLNEGKVKNIRSVTIKPNEKNDDGTKSSGEFVEISIDSSINRRVFNRFIEFLYTGVLNYLDKNDQLQETIALAESVGFKYLASACKNVLGGNEDLNPSIGTFLNDQLGETSKELFFTKKILSDIQFIVEGRSIFAHKALIFSRSNVVNALIGRNFIEREGKVEMSDDVTFDSFMAILEYLYTAHAPIEEGDSVGILVLGNRFDLRRLVSLCELYISKEIERATTIGIFRSELDIIGLLICAQRHNAPQLEKFCLHFISSNYQPMRRRKEFALLDDKTKKHIEDNQWPPIHYLRAVEDYEKEMEKLKSSSKGWFKK", "length": 598 }, "evidence": [ { "id": "A0A8C2N6K3", "url": "https://omabrowser.org/oma/group/A0A8C2N6K3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q91V93-1", "protein_name": "Rho-related BTB domain-containing protein 2", "gene_name": "Rhobtb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSGSGGPRPEDHRSHPEQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTFKSRLMVVVKMDNSIQPGPFRAVLKYLYTGELGENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIVLANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLRRQPKRRWLFWNSPSSPSSSAAGSASPSSSSSAVV", "length": 728 }, "evidence": [ { "id": "A0A8C2N6K3", "url": "https://omabrowser.org/oma/group/A0A8C2N6K3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BYZ6-1", "protein_name": "Rho-related BTB domain-containing protein 2", "gene_name": "RHOBTB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSPSSSSAVV", "length": 727 }, "evidence": [ { "id": "A0A8C2N6K3", "url": "https://omabrowser.org/oma/group/A0A8C2N6K3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2N6K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6K3" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 266, "end_pos": 442, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 374, "end_pos": 376 }, { "start_pos": 37, "end_pos": 39 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2N6L6-1", "uniprot_ac": "A0A8C2N6L6", "uniprot_id": "A0A8C2N6L6_CRIGR", "mass": { "chemical_mass": 90954.0, "monoisotopic_mass": 90954.0 }, "refseq": { "ac": "XP_027276264", "name": "enhancer of polycomb homolog 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276264" }, "gene_names": [ { "name": "Epc2", "type": "recommended", "evidence": [ { "id": "A0A8C2N6L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L6" } ] 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CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276264", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276264" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6L6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Epc2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L6", "locus": {} } ], "crossref": [ { "id": "100773541", "url": "https://www.ncbi.nlm.nih.gov/gene/100773541", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009607", "database": "InterPro", "categories": [ "Protein Classification" ] 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6Z4" } ] }, { "name": "Ap4s1", "type": "synonym", "evidence": [ { "id": "XP_003499220", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499220" } ] } ], "protein_names": [ { "name": "AP complex subunit sigma", "type": "recommended", "evidence": [ { "id": "A0A8C2N6Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6Z4/entry#names_and_taxonomy" } ] }, { "name": "AP-4 complex subunit sigma-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003499220", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499220" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 446 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613718.1) and transcript sequence (IACG01086745.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003499220", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499220" } ] }, { "annotation": "Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6Z4#function" }, { "database": "UniProtKB", "id": "ARBA00053594", "url": "https://www.uniprot.org/uniprotkb/ARBA00053594#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6Z4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ap4s1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6Z4", "locus": {} } ], "crossref": [ { "id": "cd14832", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14832", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100763289", "url": "https://www.ncbi.nlm.nih.gov/gene/100763289", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763289", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763289", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GHVVETN", "url": "https://omabrowser.org/oma/group/GHVVETN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N6Z4", "url": "https://www.orthodb.org/?gene=A0A8C2N6Z4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11753", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11753", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01217", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003499220", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499220", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N6Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIKFFLMVNKQGQTRLSKYYEHVEINKRTVLETEVIKSCLSRSSEQCSFIEYKDFKLIYRQYAALFIVVGVNDTENEMAVYEFIHNFVEVLDEYFSRVSELDIMFNLDKVHIILDEMLLNGCIVETNRARILAPLLILDKMSES", "length": 144, "header": "tr|A0A8C2N6Z4-1|A0A8C2N6Z4_CRIGR Isoform 1 of AP complex subunit sigma OS=Cricetulus griseus OX=10029 GN=Ap4s1 PE=3 SV=1 CANONICAL=A0A8C2N6Z4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N6Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6Z4/entry#A0A8C2N6Z4-1", "sequence": { "sequence": "MIKFFLMVNKQGQTRLSKYYEHVEINKRTVLETEVIKSCLSRSSEQCSFIEYKDFKLIYRQYAALFIVVGVNDTENEMAVYEFIHNFVEVLDEYFSRVSELDIMFNLDKVHIILDEMLLNGCIVETNRARILAPLLILDKMSES", "length": 144, "header": "tr|A0A8C2N6Z4-1|A0A8C2N6Z4_CRIGR Isoform 1 of AP complex subunit sigma OS=Cricetulus griseus OX=10029 GN=Ap4s1 PE=3 SV=1 CANONICAL=A0A8C2N6Z4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6Z4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6Z4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763289", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763289", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XPJ4-1", "protein_name": "AP complex subunit sigma", "gene_name": "AP4S1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MIKFFLMVNKQGQTRLSRYYEHIEIHKRTMLEAEVIKHCLSRSKDQCSFIEYKDFKLVYRQYAALFVVVGINETENEMAVYELIHNFVEVLDKYFSRVSELDIMFNLDRVHIILDEMVLNGCIVETNPNRILAPLFVLDKVAES", "length": 144 }, "evidence": [ { "id": "A0A8C2N6Z4", "url": "https://omabrowser.org/oma/group/A0A8C2N6Z4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O82201-1", "protein_name": "AP-4 complex subunit sigma", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGIRFILMVNKQGQTRLAQYYEWLTLEERRALEGEIVRKCLARNDQQCSFVEHRNYKIVYRRYASLFFMVGVDDDENELAILEFIHLLVETMDKHFGNVCELDIMFHLEKAHFMLEEMVMNGCIVETSKANILSPIQLMDKAH", "length": 143 }, "evidence": [ { "id": "A0A8C2N6Z4", "url": "https://omabrowser.org/oma/group/A0A8C2N6Z4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q3ZBB6-1", "protein_name": "AP-4 complex subunit sigma-1", "gene_name": "AP4S1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MIKFFLMVNKQGQTRLSKYYEHVEINKRTLLETEVIKSCLSRSNEQCSFIEYKDFKLIYRQYAALFIVVGVNDTENEMAIYEFIHNFVEVLDDYFSRVSELDIMFNLDKVHIILDEMVLNGCIVETNRARILAPLLILDKMSDS", "length": 144 }, "evidence": [ { "id": "A0A8C2N6Z4", "url": "https://omabrowser.org/oma/group/A0A8C2N6Z4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54NZ4-1", "protein_name": "AP-4 complex subunit sigma", "gene_name": "ap4s1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAIKYFLLVNIRGKTRLSQYYESIPFEERPAMESEIIRKCLSRTEIQCSFVEYKDYKVIYRKYATLFFIVGVDTTENELAILELIHNYVEILDSCFDNVIMFNLDKAHFILDEMVSNGDIVEISKQHILEFVNLLYKQE", "length": 139 }, "evidence": [ { "id": "A0A8C2N6Z4", "url": "https://omabrowser.org/oma/group/A0A8C2N6Z4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9WVL1-1", "protein_name": "AP-4 complex subunit sigma-1", "gene_name": "Ap4s1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIKFFLMVNKQGQTRLSKYYEHVDINKRALLETEVSKSCLSRSSEQCSFIEYKDFKLIYRQYAALFVVVGVNDTENEMAIYEFIHNFVEVLDGYFSRVSELDIMFNLDKVHIILDEMVLNGCIVETNRARILAPLLILDKLSES", "length": 144 }, "evidence": [ { "id": "A0A8C2N6Z4", "url": "https://omabrowser.org/oma/group/A0A8C2N6Z4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y587-1", "protein_name": "AP-4 complex subunit sigma-1", "gene_name": "AP4S1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIKFFLMVNKQGQTRLSKYYEHVDINKRTLLETEVIKSCLSRSNEQCSFIEYKDFKLIYRQYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDIMFNLDKVHIILDEMVLNGCIVETNRARILAPLLILDKMSES", "length": 144 }, "evidence": [ { "id": "A0A8C2N6Z4", "url": "https://omabrowser.org/oma/group/A0A8C2N6Z4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6Z4" } ], "pmid": "" } ] }, { "name": 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"Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP complex mu/sigma subunit", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 141, "start_aa": "Met", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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CCHC-type and RNA-binding motif-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_003513550", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513550" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615971.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003513550", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513550" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N728", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N728" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zcrb1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N728", "locus": {} } ], "crossref": [ { "id": "cd12393", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12393", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769243", "url": "https://www.ncbi.nlm.nih.gov/gene/100769243", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769243", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769243", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AHYFNDE", "url": "https://omabrowser.org/oma/group/AHYFNDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N728", "url": "https://www.orthodb.org/?gene=A0A8C2N728", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46259", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46259", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46259:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46259:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003513550", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513550", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N728", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N728", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N728-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N728-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRRSKGVAFILFLDKDSALNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKVPEPEEVEEVEVSEEEGEDPALDSLSQAIAFQQAKIEEEQNKWRPSPGGPSTSDDSRRPRIKKSAYFSDEEELSD", "length": 216, "header": "tr|A0A8C2N728-1|A0A8C2N728_CRIGR Isoform 1 of Zinc finger CCHC-type and RNA-binding motif-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Zcrb1 PE=4 SV=1 CANONICAL=A0A8C2N728-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N728-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N728/entry#A0A8C2N728-1", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRRSKGVAFILFLDKDSALNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKVPEPEEVEEVEVSEEEGEDPALDSLSQAIAFQQAKIEEEQNKWRPSPGGPSTSDDSRRPRIKKSAYFSDEEELSD", "length": 216, "header": "tr|A0A8C2N728-1|A0A8C2N728_CRIGR Isoform 1 of Zinc finger CCHC-type and RNA-binding motif-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Zcrb1 PE=4 SV=1 CANONICAL=A0A8C2N728-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N728", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N728" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"https://omabrowser.org/oma/group/A0A8C2N728/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BTK3-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "ZCRB1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFALTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKESAQNCSRALNNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGEAGHLSYACPKNMLGEREPPKKKEKKKRKKVVEPEEIEEEEESEEEGEDPALDSLSQAIAVQQAKIEEEQQRWTQTAGESSVSDDSKRPRIKKSAYFSDEEELSD", "length": 216 }, "evidence": [ { "id": "A0A8C2N728", "url": "https://omabrowser.org/oma/group/A0A8C2N728/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q499V6-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "Zcrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDSALNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKVPEPEEEIEEVEVSEEEGEDPALDSLSQAIAFQQAKIEEEQNKWRPSTGGPSTSDDSRRPRIKKSAYFSDEEELSD", "length": 217 }, "evidence": [ { "id": "A0A8C2N728", "url": "https://omabrowser.org/oma/group/A0A8C2N728/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q56JZ7-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "ZCRB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRRSKGVAFILFLDKDSAQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKIPEPEEEIEEVEESEDEGEDPALDSLSQAIAFQQAKIEEEQKKWKPSSGGPSTSDDSRRPRIKKSTYFSDEEELSD", "length": 217 }, "evidence": [ { "id": "A0A8C2N728", "url": "https://omabrowser.org/oma/group/A0A8C2N728/", "database": "OMA" } ], "glygen_name": "Bovine", 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Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. 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"MLLTMLLLLLLLSPDSQTAHGHPLYMRLSPSTLQVLSAQGTQALQAAQRRAQWAIKRVLMEIQHRLHECQGPGRHRPQATPLQDPPELGPCGERHQGVANVTRAHSRIVGGNTAPSGAWPWLVRLQLGGQPLCGGVLVATSWVLTAAHCFSGASNELLWTVTLAEGPQGEQAEEVQVNRILPHPKFDPQTFHNDLALVQLWTPVSPGGPARPICLPQGSREPPAGTPCAIAGWGALFEDGPESEAVREARVPLLSADTCQKALGPGLRPSTMLCAGYLAGGIDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAAPSTREPSCRELLTWEPPEEERVPDAAGLCAFYARLCPGSELSCAHLALQQCLQRRRRCELRSLAHTLLGLLRGAQELLGPGPGLRRGVPAPARSAPSLREPPGHNVREQQLYSGSRVAGTWFQKPKPERRAETKGCPGLEPLQQKLAAIQRAHAWILQIPAEHLAMNFHEVLADLGSKALTGLFRAWVRASLGDQRVVFSGLVGLEPSTLARSTPRLLVQALKAFRSVFQTEESQEPWMRVGQGQRLGKEHHRQLQHLVP", "length": 602, "header": "tr|A0A8C2N7F5-1|A0A8C2N7F5_CRIGR Isoform 1 of Serine protease 56 OS=Cricetulus griseus OX=10029 GN=Prss56 PE=4 SV=1 CANONICAL=A0A8C2N7F5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N7F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N7F5/entry#A0A8C2N7F5-1", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304155", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304155" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N7N7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N7N7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Alox15", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N7N7", "locus": {} } ], "crossref": [ { "id": "100764916", "url": "https://www.ncbi.nlm.nih.gov/gene/100764916", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000907", "database": "InterPro", "categories": [ "Protein Classification" ] 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This record is derived from a genomic sequence (NW_003613773.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003500141", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500141" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N8U5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N8U5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nans", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N8U5", "locus": {} } ], "crossref": [ { "id": "cd11615", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11615", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767837", "url": "https://www.ncbi.nlm.nih.gov/gene/100767837", "database": "GeneID", "categories": [ "Genome 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"MPLELELCPGRWVGGQHPCFIIAEIGQNHQGDLDIAKRMIRTAKECGADCAKFQKSELEFKFNRKALERPYTSKHSWGTTYGEHKRHLEFSHAQYKELQRYAQEIGIFFTASGMDEMAVEFLHELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNFCFLQCTSAYPLQPEDANLRVISEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHITLDKTWKGSDHSASLEPGELAELVRSVRLVERALGSPTKQLLPCEMACNEKLGKSVVAKVRIPEGTVLTLDMLTVKVGEPKGYPPEDIFNLVGKKMLVTVEEDDTILEDSVENHSKKIKS", "length": 359, "header": "tr|A0A8C2N8U5-1|A0A8C2N8U5_CRIGR Isoform 1 of N-acetylneuraminate-9-phosphate synthase OS=Cricetulus griseus OX=10029 GN=Nans PE=4 SV=1 CANONICAL=A0A8C2N8U5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N8U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N8U5/entry#A0A8C2N8U5-1", "sequence": { "sequence": 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N8U5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N8U5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767837", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767837", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B1WC26-1", "protein_name": "N-acetylneuraminate-9-phosphate synthase", "gene_name": "Nans", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613890.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003613652.1) and transcript sequence (IACG01088914.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007611536.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007611536", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007611536" } ] }, { "annotation": "GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2NC96", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96#function" }, { "database": "UniProtKB", "id": "RU369003", "url": "https://www.uniprot.org/uniprotkb/RU369003#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2NC96", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Arf5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96", "locus": {} } ], "crossref": [ { "id": "cd04150", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04150", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759676", "url": "https://www.ncbi.nlm.nih.gov/gene/100759676", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759676", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759676", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2NC96", "url": "https://www.orthodb.org/?gene=A0A8C2NC96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007611536", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007611536", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2NC96", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2NC96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR", "length": 180, "header": "tr|A0A8C2NC96-1|A0A8C2NC96_CRIGR Isoform 1 of ADP-ribosylation factor OS=Cricetulus griseus OX=10029 GN=Arf5 PE=3 SV=1 CANONICAL=A0A8C2NC96-1" }, "isoforms": [ { "isoform_ac": "A0A8C2NC96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96/entry#A0A8C2NC96-1", "sequence": { "sequence": "MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR", "length": 180, "header": "tr|A0A8C2NC96-1|A0A8C2NC96_CRIGR Isoform 1 of ADP-ribosylation factor OS=Cricetulus griseus OX=10029 GN=Arf5 PE=3 SV=1 CANONICAL=A0A8C2NC96-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2NC96", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2NC96", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759676", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759676", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2NC96", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2NC96", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2NC96", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2NC96", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2NC96", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2NC96", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2NC96", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A8C2NC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96#function" }, { "id": "A0A8C2NC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96" }, { "id": "PIRSR606689-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR606689-2" } ], "binding_site_uniprot": 31, "amino_acid": "Thr", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 31, "end_pos": 31, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2NC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96#function" }, { "id": "A0A8C2NC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NC96" }, { "id": "PIRSR606689-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR606689-2" } ], "binding_site_uniprot": 48, "amino_acid": "Thr", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 48, "end_pos": 48, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QBJ9-1", "uniprot_ac": "A0A8C2QBJ9", "uniprot_id": "A0A8C2QBJ9_CRIGR", "mass": { "chemical_mass": 22019.0, "monoisotopic_mass": 22019.0 }, "refseq": { "ac": "XP_027264024", "name": "AP-3 complex subunit sigma-2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264024" }, "gene_names": [ { "name": "LOC100754298", "type": "recommended", "evidence": [ { "id": "A0A8C2QBJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9" } ] }, { "name": "LOC100754298", "type": "synonym", "evidence": [ { "id": "XP_027264024", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264024" } ] } ], "protein_names": [ { "name": "AP-3 complex subunit sigma-2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027264024", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264024" }, { "id": "A0A8C2QBJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027264024", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264024" } ] }, { "annotation": "Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKG9#function" }, { "database": "UniProtKB", "id": "ARBA00025605", "url": "https://www.uniprot.org/uniprotkb/ARBA00025605#function" }, { "database": "UniProtKB", "id": "A0A8C2QBJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100754298", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9", "locus": {} } ], "crossref": [ { "id": "cd14834", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14834", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754298", "url": "https://www.ncbi.nlm.nih.gov/gene/100754298", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754298", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754298", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QBJ9", "url": "https://www.orthodb.org/?gene=A0A8C2QBJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11753", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11753", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01217", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027264024", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264024", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QBJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QBJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JDN5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JDN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGADYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNMNLPEIPRNINIGDLNIKVPNLSQFV", "length": 193, "header": "tr|A0A8C2QBJ9-1|A0A8C2QBJ9_CRIGR Isoform 1 of AP-3 complex subunit sigma-2 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100754298 PE=3 SV=1 CANONICAL=A0A8C2QBJ9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QBJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9/entry#A0A8C2QBJ9-1", "sequence": { "sequence": "MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGADYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNMNLPEIPRNINIGDLNIKVPNLSQFV", "length": 193, "header": "tr|A0A8C2QBJ9-1|A0A8C2QBJ9_CRIGR Isoform 1 of AP-3 complex subunit sigma-2 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100754298 PE=3 SV=1 CANONICAL=A0A8C2QBJ9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JDN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9/entry#A0A9J7JDN5-1", "sequence": { "sequence": "MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGADYKLIYRHYATLYFVFCVDSSESELGILDLIQVHYILQEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNMNLPEIPRNINIGDLNIKVPNLSQFV", "length": 169, "header": "tr|A0A9J7JDN5-1|A0A9J7JDN5_CRIGR Computationally mapped isoform of AP-3 complex subunit sigma-2 isoform X4 OS=Cricetulus griseus OX=10029 GN=LOC100754298 PE=3 SV=1 CANONICAL=A0A8C2QBJ9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9/entry#A0A9J7JKG9-1", "sequence": { "sequence": "MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGADYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKGGLSAAPARAVSAVKNMNLPEIPRNINIGDLNIKVPNLSQFV", "length": 157, "header": "tr|A0A9J7JKG9-1|A0A8C2QBJ9_CRIGR Computationally mapped isoform of AP-3 complex subunit sigma-2 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100754298 PE=3 SV=1 CANONICAL=A0A8C2QBJ9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKG9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754298", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754298", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9" } ], "pmid": "" }, { "name": "AP-3 adaptor complex", "id": "GO:0030123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030123", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9" } ], "pmid": "" }, { "name": "membrane coat", "id": "GO:0030117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030117", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9" } ], "pmid": "" }, { "name": "anterograde synaptic vesicle transport", "id": "GO:0048490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048490", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QBJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBJ9" }, { "id": "PF01217", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP complex mu/sigma subunit", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 147, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QBP3-1", "uniprot_ac": "A0A8C2QBP3", "uniprot_id": "A0A8C2QBP3_CRIGR", "mass": { "chemical_mass": 59134.0, "monoisotopic_mass": 59134.0 }, "refseq": { "ac": "XP_027284244", "name": "acid-sensing ion channel 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284244" }, "gene_names": [ { "name": "Asic3", "type": "recommended", "evidence": [ { "id": "A0A8C2QBP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBP3" } ] }, { "name": "Asic3", "type": "synonym", "evidence": [ 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REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027284244", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284244" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBP3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Asic3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBP3", "locus": {} } ], "crossref": [ { "id": "100763386", "url": "https://www.ncbi.nlm.nih.gov/gene/100763386", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001873", "database": "InterPro", "categories": [ "Protein Classification" ] 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"MKPPSGLEEARQRQRQASDIRVFASSCTMHGLGHVFGPGGLTLRRGLWATAVLLSLAAFLYQVAERVRYYGEFHHKTTLDERESHQLTFPAVTLCNINPLRRSRLTPNDLHWAGTALLGLDPAEHAAYLRALGQPPAPPGFMPSPTFDMAQLYARAGHSLEDMLLDCRYRGQPCGPENFTVIFTRMGQCYTFNSGAYGAELLTTPKGGAGNGLEIMLDVQQEEYLPIWKDMEETPFEVGIRVQIHSQEEPPAIDQLGFGAAPGHQTFVSCQQQQLSFLPPPWGDCNTASVDPDFDTEPSDPLGSPNLSPSPPYSLIGCRLACETRYVARKCGCRMMHMPGNSPVCSPQQYKDCASPALDAMLRKDTCVCPNPCATTRYAKELSMVRIPSRASARYLAQKYNRSETYIAENVLVLDIFFEALNYEAVEQKAAYEVSELLGDIGGQMGLFIGASLLTILEILDYLCEVFQDRVLGYFWNRRSSQRHSGSTLLQEGLDGHRTHVPHLSLGPRPPTPPSAVTKTLSASHRTCYLVTRL", "length": 534, "header": "tr|A0A8C2QBP3-1|A0A8C2QBP3_CRIGR Isoform 1 of Acid-sensing ion channel 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Asic3 PE=4 SV=1 CANONICAL=A0A8C2QBP3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QBP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBP3/entry#A0A8C2QBP3-1", "sequence": { "sequence": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035299153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299153" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBU2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBU2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Srrm4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBU2", "locus": {} } ], "crossref": [ { "id": "100754359", "url": "https://www.ncbi.nlm.nih.gov/gene/100754359", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754359", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754359", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QBU2", "url": "https://www.orthodb.org/?gene=A0A8C2QBU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34755", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34755", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34755:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34755:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15230", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15230", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035299153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299153", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QBU2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QBU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLQQGEKQLFEKFWKGTFKAVATPRPESIIVASITARKPLPRTEPQSNLLVPAQGGPSEKLSHRLTTETFGTNSWEREKPCRELDPARAHSASQDRDLTPPPSSRGKKKKKKSTRKKRRRSPSYSPSPVKKKKKKSSKKHKRHRSFSKKRRHSSCSPKSKRREEKKHKKQSRSRKSHRHRHHRCPSRSQSSELRSSSCESRHRGRSPEEGRKSRRTHSRRCSKNHCKVSPEARSSHLPSQPLQRLGFLPARGVISGSGSAADLFSKSTSPLTASRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPGGGLSKSRDLNCGNTSDSGNSFTTSSPQNKGAVLENVSPTCRSSESRGFQSPCLQCAEVKKSSLVPSTARSSPIKECSRSSSYTSTRSSSPSSRSPNHRASPRYTRSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRDPKYGEKELQPRERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSSSLSSASSWYSSSSSRSASRSYSRSRSPSRSRSRSRSQTRSRTRTSRSSSSRSLSLGSRSRSRSRSLSYSSAESYASTRR", "length": 601, "header": "tr|A0A8C2QBU2-1|A0A8C2QBU2_CRIGR Isoform 1 of Serine/arginine repetitive matrix protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Srrm4 PE=4 SV=1 CANONICAL=A0A8C2QBU2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QBU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBU2/entry#A0A8C2QBU2-1", "sequence": { "sequence": "MASLQQGEKQLFEKFWKGTFKAVATPRPESIIVASITARKPLPRTEPQSNLLVPAQGGPSEKLSHRLTTETFGTNSWEREKPCRELDPARAHSASQDRDLTPPPSSRGKKKKKKSTRKKRRRSPSYSPSPVKKKKKKSSKKHKRHRSFSKKRRHSSCSPKSKRREEKKHKKQSRSRKSHRHRHHRCPSRSQSSELRSSSCESRHRGRSPEEGRKSRRTHSRRCSKNHCKVSPEARSSHLPSQPLQRLGFLPARGVISGSGSAADLFSKSTSPLTASRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPGGGLSKSRDLNCGNTSDSGNSFTTSSPQNKGAVLENVSPTCRSSESRGFQSPCLQCAEVKKSSLVPSTARSSPIKECSRSSSYTSTRSSSPSSRSPNHRASPRYTRSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRDPKYGEKELQPRERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSSSLSSASSWYSSSSSRSASRSYSRSRSPSRSRSRSRSQTRSRTRTSRSSSSRSLSLGSRSRSRSRSLSYSSAESYASTRR", "length": 601, "header": "tr|A0A8C2QBU2-1|A0A8C2QBU2_CRIGR Isoform 1 of Serine/arginine repetitive matrix protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Srrm4 PE=4 SV=1 CANONICAL=A0A8C2QBU2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"url": "https://www.uniprot.org/uniprotkb/A0A8C2QBU2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBU2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBU2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBU2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBU2" } ], "pmid": "" }, { "name": "neuron maturation", "id": "GO:0042551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042551", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBU2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBU2" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBU2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QBU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBU2" }, { "id": "PF15230", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15230" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serine/arginine repetitive matrix protein 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307168", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307168" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBW5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBW5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fstl5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBW5", "locus": {} } ], "crossref": [ { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00104", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00104", "database": "CDD", 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"header": "tr|A0A8C2QBW5-1|A0A8C2QBW5_CRIGR Isoform 1 of Follistatin-related protein 5 OS=Cricetulus griseus OX=10029 GN=Fstl5 PE=4 SV=1 CANONICAL=A0A8C2QBW5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QBW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBW5/entry#A0A8C2QBW5-1", "sequence": { "sequence": "MFKSWSAVFILGFIFLESEGRPTKESGYGIKSYQPLTRLRHKQEKTQESSRIKGFLIQDSPFGSCENKFCGLGRHCVISRETRHAECACMDVCKQHYKPVCGSDGEFYENHCEVHRAACLKKQKITIVHNEDCFFKGDNCLATEYSKMKSMLLDLQNQKYITQENENSNGDDISRKKLLVDQMFKHFDADSNGLVDINELTQVIKQEELNKDFSDCTLYDLLKYDDFNADKHLALEEFYRTFQVIQLSLPEDQRVSITAATVGQSAVLSCAIVGALRPPIIWKRNNIVLNNLDLEDINDFGDDGSLYITKVTTVHMGNYTCYADGYEHVHQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPDPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIARNEAGVDEDISSLFVEDSARKTLANILWREEGLGIGNMFYVFYEDGIKVIQPTECEFQRHIKPSEKLLGFQDEVCPKDEEDEVQRCVWASAVNVKDKFIYVAQPTLDRILIVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVLSWGSMEKTSPTLQVITLASGNMPHHTIHTQPVGKQFDRVDDFFIPTTTLIITHMRFGFILHKDEAALHKIDLETMSYIKTINLKDSKCIPLSLAYTHLGGYYFISCKPDVTGALPPQLVVDSVTDSVIGFNSDVTGTPYISPDGHYLVSVNDVKGLVRVQYITIRGEILDAFDIHTNLHISDLAFQPSFTEAHQYNIYGSSGQQTDVLFVELSSGKVKMIKSLKEPLKTEDWPWSRKNRHIQGSGLFGQYLMTPSKDSLFILDGRLNKLNCEITEVQKGNTVVWVGDA", "length": 847, "header": "tr|A0A8C2QBW5-1|A0A8C2QBW5_CRIGR Isoform 1 of Follistatin-related protein 5 OS=Cricetulus griseus OX=10029 GN=Fstl5 PE=4 SV=1 CANONICAL=A0A8C2QBW5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBW5/entry#A0A9J7HAN2-1", "sequence": { "sequence": "MFKSWSAVFILGFIFLESEGRPTKESGYGIKSYQPLTRLRHKEKTQESSRIKGFLIQDSPFGSCENKFCGLGRHCVISRETRHAECACMDVCKQHYKPVCGSDGEFYENHCEVHRAACLKKQKITIVHNEDCFFKGDNCLATEYSKMKSMLLDLQNQKYITQENENSNGDDISRKKLLVDQMFKHFDADSNGLVDINELTQVIKQEELNKDFSDCTLYDLLKYDDFNADKHLALEEFYRTFQVIQLSLPEDQRVSITAATVGQSAVLSCAIVGALRPPIIWKRNNIVLNNLDLEDINDFGDDGSLYITKVTTVHMGNYTCYADGYEHVHQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPDPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIARNEAGVDEDISSLFVEDSARKTRLGIGNMFYVFYEDGIKVIQPTECEFQRHIKPSEKLLGFQDEVCPKDEEDEVQRCVWASAVNVKDKFIYVAQPTLDRILIVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVLSWGSMEKTSPTLQVITLASGNMPHHTIHTQPVGKQFDRVDDFFIPTTTLIITHMRFGFILHKDEAALHKIDLETMSYIKTINLKDSKCIPLSLAYTHLGGYYFISCKPDVTGALPPQLVVDSVTDSVIGFNSDVTGTPYISPDGHYLVSVNDVKGLVRVQYITIRGEILDAFDIHTNLHISDLAFQPSFTEAHQYNIYGSSGQQTDVLFVELSSGKVKMIKSLKEPLKTEDWPWSRKNRHIQGSGLFGQYLMTPSKDSLFILDGRLNKLNCEITEVQKGNTVVWVGDA", "length": 837, "header": "tr|A0A9J7HAN2-1|A0A9J7HAN2_CRIGR Computationally mapped isoform of Follistatin-related protein 5 OS=Cricetulus griseus OX=10029 GN=Fstl5 PE=4 SV=1 CANONICAL=A0A8C2QBW5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBW5/entry#A0A9J7KAX9-1", "sequence": { "sequence": "MFKSWSAVFILGFIFLESEGRPTKESGYGIKSYQPLTRLRHKEKTQESSRIKGFLIQDSPFGSCENKFCGLGRHCVISRETRHAECACMDVCKQHYKPVCGSDGEFYENHCEVHRAACLKKQKITIVHNEDCFFKGDNCLATEYSKMKSMLLDLQNQKYITQENENSNGDDISRKKLLVDQMFKHFDADSNGLVDINELTQVIKQEELNKDFSDCTLYDLLKYDDFNADKHLALEEFYRTFQVIQLSLPEDQRVSITAATVGQSAVLSCAIVGALRPPIIWKRNNIVLNNLDLEDINDFGDDGSLYITKVTTVHMGNYTCYADGYEHVHQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPDPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIARNEAGVDEDISSLFVEDSARKTLANILWREEGLGIGNMFYVFYEDGIKVIQPTECEFQRHIKPSEKLLGFQDEVCPKDEEDEVQRCVWASAVNVKDKFIYVAQPTLDRILIVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVLSWGSMEKTSPTLQVITLASGNMPHHTIHTQPVGKQFDRVDDFFIPTTTLIITHMRFGFILHKDEAALHKIDLETMSYIKTINLKDSKCIPLSLAYTHLGGYYFISCKPDVTGALPPQLVVDSVTDSVIGFNSDVTGTPYISPDGHYLVSVNDVKGLVRVQYITIRGEILDAFDIHTNLHISDLAFQPSFTEAHQYNIYGSSGQQTDVLFVELSSGKVKMIKSLKEPLKTEDWPWSRKNRHIQGSGLFGQYLMTPSKDSLFILDGRLNKLNCEITEVQKGNTVVWVGDA", "length": 846, "header": "tr|A0A9J7KAX9-1|A0A8C2QBW5_CRIGR Computationally mapped isoform of Follistatin-related protein 5 OS=Cricetulus griseus OX=10029 GN=Fstl5 PE=4 SV=1 CANONICAL=A0A8C2QBW5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAX9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAX9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752648", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752648", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBW5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBW5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBW5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBW5" } ], "pmid": "" }, { "name": "regulation of BMP signaling pathway", "id": "GO:0030510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030510", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBW5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBW5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBW5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QBW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBW5" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 175, "end_pos": 210, "start_aa": "Arg", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2QBW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBW5" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 250, "end_pos": 323, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2QBW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBW5" }, { "id": "PS51465", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000259", "start_pos": 81, "end_pos": 135, "start_aa": "Glu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 318, "end_pos": 320 }, { "start_pos": 394, "end_pos": 396 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QBZ1-1", "uniprot_ac": "A0A8C2QBZ1", "uniprot_id": "A0A8C2QBZ1_CRIGR", "mass": { "chemical_mass": 31056.0, "monoisotopic_mass": 31056.0 }, "refseq": { "ac": "XP_027271147", "name": "CTD small phosphatase-like protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271147" }, "gene_names": [ { "name": "Ctdspl", "type": "recommended", "evidence": [ { "id": "A0A8C2QBZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ] }, { "name": "Ctdspl", "type": "synonym", "evidence": [ { "id": "XP_027271147", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271147" } ] } ], "protein_names": [ { "name": "protein-serine/threonine phosphatase", "type": "recommended", "evidence": [ { "id": "A0A8C2QBZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "A0A8C2QBZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1/entry#names_and_taxonomy" } ] }, { "name": "CTD small phosphatase-like protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027271147", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271147" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271147" } ] }, { "annotation": "Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GWP5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWP5#function" }, { "database": "UniProtKB", "id": "RU365079", "url": "https://www.uniprot.org/uniprotkb/RU365079#function" } ] }, { "annotation": "Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1#function" }, { "database": "UniProtKB", "id": "ARBA00057890", "url": "https://www.uniprot.org/uniprotkb/ARBA00057890#function" }, { "database": "UniProtKB", "id": "A0A8C2LAT4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAT4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ctdspl", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1", "locus": {} } ], "crossref": [ { "id": "cd07521", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07521", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754751", "url": "https://www.ncbi.nlm.nih.gov/gene/100754751", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004274", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004274", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011948", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011948", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754751", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754751", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QBZ1", "url": "https://www.orthodb.org/?gene=A0A8C2QBZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JMS1", "url": "https://www.orthodb.org/?gene=A0A9J7JMS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12210", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12210", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271147", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LAT4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LAT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QBZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QBZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWP5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMS1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGPAIITQVTNPKEDEARSPGAGEKASQRSLSLKKQRGRSILSSFFCCFRDYNVEAPLPSSPSVLPPLVEENSGLQKGDQRQVIPVPSPPAKSLLPEVTVLDYGKKCVVIDLDETLVHSSFKPISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLFECVLFTASLAKYADPVADLLDRWGVFRARLFRESCVFHRGNYVKDLSRLGRELSKVIIVDNSPASYIFHPENAVPVQSWFDDMTDTELLDLIPFFEGLSREDDVYSMLHRLCSR", "length": 276, "header": "tr|A0A8C2QBZ1-1|A0A8C2QBZ1_CRIGR Isoform 1 of protein-serine/threonine phosphatase OS=Cricetulus griseus OX=10029 GN=Ctdspl PE=4 SV=1 CANONICAL=A0A8C2QBZ1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LAT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1/entry#A0A8C2LAT4-1", "sequence": { "sequence": "MDGPAIITQVTNPKEDEARSPGAGEKASQRSLSLKKQRGRSILSSFFCCFRDYNVEAPLPSSPSVLPPLVEENSGLQKPPAKSLLPEVTVLDYGKKCVVIDLDETLVHSSFKPISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLFECVLFTASLAKYADPVADLLDRWGVFRARLFRESCVFHRGNYVKDLSRLGRELSKVIIVDNSPASYIFHPENAVPVQSWFDDMTDTELLDLIPFFEGLSREDDVYSMLHRLCSR", "length": 265, "header": "tr|A0A8C2LAT4-1|A0A8C2LAT4_CRIGR Computationally mapped isoform of protein-serine/threonine phosphatase OS=Cricetulus griseus OX=10029 GN=Ctdspl PE=4 SV=1 CANONICAL=A0A8C2QBZ1-1" }, "locus": {} }, { "isoform_ac": "A0A8C2QBZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1/entry#A0A8C2QBZ1-1", "sequence": { "sequence": "MDGPAIITQVTNPKEDEARSPGAGEKASQRSLSLKKQRGRSILSSFFCCFRDYNVEAPLPSSPSVLPPLVEENSGLQKGDQRQVIPVPSPPAKSLLPEVTVLDYGKKCVVIDLDETLVHSSFKPISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLFECVLFTASLAKYADPVADLLDRWGVFRARLFRESCVFHRGNYVKDLSRLGRELSKVIIVDNSPASYIFHPENAVPVQSWFDDMTDTELLDLIPFFEGLSREDDVYSMLHRLCSR", "length": 276, "header": "tr|A0A8C2QBZ1-1|A0A8C2QBZ1_CRIGR Isoform 1 of protein-serine/threonine phosphatase OS=Cricetulus griseus OX=10029 GN=Ctdspl PE=4 SV=1 CANONICAL=A0A8C2QBZ1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GWP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1/entry#A0A9J7GWP5-1", "sequence": { "sequence": "MDGPAIITQVTNPKEDEARSPGAGEKASQRSLSLKKQRGRSILSSFFCCFRDYNVEAPLPSSPSVLPPLVEENSGLQKGDQRQVIPVPSPPAKSLLPEVTVLDYGKKCVVIDLDETLVHSSFKPISNADFIVPVEIDGTIHQYADPVADLLDRWGVFRARLFRESCVFHRGNYVKDLSRLGRELSKVIIVDNSPASYIFHPENAVPVQSWFDDMTDTELLDLIPFFEGLSREDDVYSMLHRLCSR", "length": 245, "header": "tr|A0A9J7GWP5-1|A0A9J7GWP5_CRIGR Computationally mapped isoform of Mitochondrial import inner membrane translocase subunit TIM50 OS=Cricetulus griseus OX=10029 GN=Ctdspl PE=3 SV=1 CANONICAL=A0A8C2QBZ1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JMS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1/entry#A0A9J7JMS1-1", "sequence": { "sequence": "MGQLFECVLFTASLAKYADPVADLLDRWGVFRARLFRESCVFHRGNYVKDLSRLGRELSKVIIVDNSPASYIFHPENAVPVQSWFDDMTDTELLDLIPFFEGLSREDDVYSMLHRLCSR", "length": 119, "header": "tr|A0A9J7JMS1-1|A0A8C2QBZ1_CRIGR Computationally mapped isoform of protein-serine/threonine phosphatase OS=Cricetulus griseus OX=10029 GN=Ctdspl PE=4 SV=1 CANONICAL=A0A8C2QBZ1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JMS1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMS1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JMS1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMS1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754751", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754751", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000134", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II CTD heptapeptide repeat phosphatase activity", "id": "GO:0008420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008420", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "TIM23 mitochondrial import inner membrane translocase complex", "id": "GO:0005744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005744", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GV48-1", "G3GWQ6-1", "G3H060-1", "G3H9Q0-1", "G3H7Z6-1", "G3I157-1", "G3HCQ6-1", "A0A8C2MA30-1", "G3HMJ7-1", "G3I434-1", "G3H622-1", "G3HKY7-1", "G3GRD1-1", "G3I4H5-1", "G3H8H2-1", "A0A9J7F890-1", "A0A8C2MW37-1", "A0A061I6V7-1", "A0A9J7GBP5-1", "A0A9J7JFN8-1", "A0A9J7G7W0-1", "A0A9J7GE78-1", "A0A061HVT3-1", "A0A061HX98-1", "A0A3L7HX32-1", "A0A8C2LYQ8-1", "A0A8C2M5N0-1", "A0A9J7JBH1-1", "A0A9J7EY47-1", "A0A8C2LGL9-1", "A0A8C2LVB9-1", "A0A8C2QH88-1", "A0A9J7F130-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FXD0-1", "A0A9J7G243-1", "A0A9J7GEM4-1", "A0A9J7G1B8-1", "A0A9J7K1J8-1", "A0A9J7K5S1-1", "A0A9J7EZL1-1", "A0A8C2QCP2-1", "A0A8C2LTP5-1", "A0A8C2N2E5-1", "A0A8C2QBZ1-1", "A0A3L7HBF4-1", "A0A9J7GK96-1", "A0A8C2LI03-1", "A0A9J7G0U7-1", "A0A9J7GD33-1", "A0A9J7H9S5-1", "A0A9J7HCJ8-1", "A0A9J7GJY7-1", "A0A9J7JYW1-1", "A0A3L7I513-1", "A0A9J7FKB3-1", "A0A8C2LGY1-1", "A0A3L7HEM4-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GV48-1", "G3GWQ6-1", "G3H060-1", "G3H9Q0-1", "G3H622-1", "G3HKY7-1", "G3H7Z6-1", "G3I157-1", "G3HCQ6-1", "A0A8C2MA30-1", "G3HMJ7-1", "A0A8C2MF90-1", "A0A9J7GX39-1", "G3I434-1", "G3GRD1-1", "G3I4H5-1", "G3H8H2-1", "A0A9J7F890-1", "A0A8C2MW37-1", "A0A061I6V7-1", "A0A9J7GBP5-1", "A0A9J7JFN8-1", "A0A9J7G7W0-1", "A0A9J7GE78-1", "A0A061HX98-1", "A0A3L7HEJ5-1", "A0A3L7HX32-1", "A0A8C2LYQ8-1", "A0A8C2M5N0-1", "A0A9J7JBH1-1", "A0A8C2ME51-1", "A0A8C2MTQ0-1", "A0A3L7IJ01-1", "A0A9J7EY47-1", "A0A8C2LGL9-1", "A0A8C2LVB9-1", "A0A8C2QH88-1", "A0A9J7F130-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FXD0-1", "A0A9J7G243-1", "A0A9J7GEM4-1", "A0A9J7G1B8-1", "A0A9J7K1J8-1", "A0A9J7K5S1-1", "A0A9J7EZL1-1", "A0A9J7F6Q7-1", "A0A8C2N2E5-1", "A0A8C2LTP5-1", "A0A8C2QBZ1-1", "A0A8C2QCP2-1", "A0A3L7HBF4-1", "A0A3L7HC66-1", "A0A9J7GK96-1", "A0A8C2LI03-1", "A0A9J7G0U7-1", "A0A9J7GD33-1", "A0A9J7H9S5-1", "A0A9J7HCJ8-1", "A0A9J7GJY7-1", "A0A9J7JXQ8-1", "A0A9J7JYW1-1", "A0A9J7FKB3-1", "A0A8C2LGY1-1", "A0A3L7HEM4-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HVT3", "gene_name": "Ppm1k", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.52", "activity": "O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + H2O = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.52", "activity": "", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] } ] }, { "uniprot_ac": "A0A061HX98", "gene_name": "Dusp9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] } ] }, { "uniprot_ac": "A0A061I6V7", "gene_name": "Pgam5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061I6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6V7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061I6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6V7" } ] } ] }, { "uniprot_ac": "A0A3L7HBF4", "gene_name": "Cpped1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBF4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBF4" } ] } ] }, { "uniprot_ac": "A0A3L7HC66", "gene_name": "Ppp6c", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HC66" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HC66" } ] } ] }, { "uniprot_ac": "A0A3L7HEJ5", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] } ] }, { "uniprot_ac": "A0A3L7HEM4", "gene_name": "Ctdspl2", "activity": [ { 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"id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] } ] }, { "uniprot_ac": "A0A3L7I513", "gene_name": "Pdxp", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] } ] }, { "uniprot_ac": "A0A3L7IJ01", "gene_name": "Ppp2cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7IJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJ01" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7IJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJ01" } ] } ] }, { "uniprot_ac": "A0A8C2LGL9", "gene_name": "Ppp1cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LGL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGL9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LGL9", "database": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] } ] }, { "uniprot_ac": "A0A8C2LYQ8", "gene_name": "Ppm1l", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYQ8" } ] } ] }, { "uniprot_ac": "A0A8C2M5N0", "gene_name": "Ppp1cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2M5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5N0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2M5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5N0" } ] } ] }, { "uniprot_ac": "A0A8C2MA30", "gene_name": "Phlpp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MA30" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MA30" } ] } ] }, { "uniprot_ac": "A0A8C2ME51", "gene_name": "Ppm1g", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2ME51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ME51" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2ME51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ME51" } ] } ] }, { "uniprot_ac": "A0A8C2MF90", "gene_name": "Ssh2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MF90" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MF90" } ] } ] }, { "uniprot_ac": "A0A8C2MTQ0", "gene_name": "Ssh1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTQ0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTQ0" } ] } ] }, { "uniprot_ac": "A0A8C2MW37", "gene_name": "Ppp3cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ] } ] }, { "uniprot_ac": "A0A8C2N2E5", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": 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"A0A8C2QH88", "gene_name": "Dusp12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] } ] }, { "uniprot_ac": "A0A9J7EY47", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] } ] }, { "uniprot_ac": "A0A9J7EZL1", "gene_name": "LOC113830718", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] } ] }, { "uniprot_ac": "A0A9J7FMB0", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] } ] }, { "uniprot_ac": "A0A9J7FWJ6", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FXD0", "gene_name": "Ppm1f", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXD0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXD0" } ] } ] }, { "uniprot_ac": "A0A9J7G0U7", "gene_name": "Pptc7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ] } ] }, { "uniprot_ac": "A0A9J7G1B8", "gene_name": "Phlpp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B8" } ] } ] }, { "uniprot_ac": "A0A9J7G243", "gene_name": "Ppm1a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G243" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G243" } ] } ] }, { "uniprot_ac": "A0A9J7G7W0", "gene_name": "Ptpmt1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.27", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] } ] }, { 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"evidence": [ { "id": "A0A9J7GEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEM4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEM4" } ] } ] }, { "uniprot_ac": "A0A9J7GJY7", "gene_name": "Ppef1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJY7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJY7" } ] } ] }, { "uniprot_ac": "A0A9J7GK96", "gene_name": "Ppm1n", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GK96", "database": 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{ "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] } ] }, { "uniprot_ac": "A0A9J7JFN8", "gene_name": "Epm2a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] } ] }, { "uniprot_ac": "A0A9J7JXQ8", "gene_name": "Ppp2ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXQ8" } ] } ] }, { "uniprot_ac": "A0A9J7JYW1", "gene_name": "Ctdnep1", "activity": [ { "ec_number": 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"database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QBZ3", "url": "https://www.orthodb.org/?gene=A0A8C2QBZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FMT9", "url": "https://www.orthodb.org/?gene=A0A9J7FMT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11732", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11732", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003495005", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495005", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QBZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QBZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FMT9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FMT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMT9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSKIQCMKLNDGHFIPVLGFGTAVPEKFSKSKIKEPIKIAIEAGIYHFDCASIYKTEEYVGESIRTKIADGTLRREDIFYTSKVWCNCLRPELVRSSLEQSLKKVQLDYVDLYIMHFPMALKPGEEEFPVDEHGKLIFDTVDLCVTWEAMEKCKDAGLTKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYLNQMKLLDFCKSNDIALVAYGVLGTQRYTGWVDQNSPVLLDEPVLHCMAKKYNRTPALIALRYQLQRGIVALNSTFNEEHIKENIQVFEFQLSSEDMKVLDGLNRNQRYVTALIFDGHPNFPFSDEY", "length": 323, "header": "tr|A0A8C2QBZ3-1|A0A8C2QBZ3_CRIGR Isoform 1 of Aldo-keto reductase family 1 member C21-like isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100770388 PE=3 SV=1 CANONICAL=A0A8C2QBZ3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QBZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ3/entry#A0A8C2QBZ3-1", "sequence": { "sequence": "MNSKIQCMKLNDGHFIPVLGFGTAVPEKFSKSKIKEPIKIAIEAGIYHFDCASIYKTEEYVGESIRTKIADGTLRREDIFYTSKVWCNCLRPELVRSSLEQSLKKVQLDYVDLYIMHFPMALKPGEEEFPVDEHGKLIFDTVDLCVTWEAMEKCKDAGLTKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYLNQMKLLDFCKSNDIALVAYGVLGTQRYTGWVDQNSPVLLDEPVLHCMAKKYNRTPALIALRYQLQRGIVALNSTFNEEHIKENIQVFEFQLSSEDMKVLDGLNRNQRYVTALIFDGHPNFPFSDEY", "length": 323, "header": "tr|A0A8C2QBZ3-1|A0A8C2QBZ3_CRIGR Isoform 1 of Aldo-keto reductase family 1 member C21-like isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100770388 PE=3 SV=1 CANONICAL=A0A8C2QBZ3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FMT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ3/entry#A0A9J7FMT9-1", "sequence": { "sequence": "MNSKIQCMKLNDGHFIPVLGFGTAVPEKFSKSKIKEPIKIAIEAGIYHFDCASIYKTEEYVGESIRTKIADGTLRREDIFYTSKVWCNCLRPELVRSSLEQSLKKVQLDYVDLYIMHFPMALKAMEKCKDAGLTKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYLNQMKLLDFCKSNDIALVAYGVLGTQRYTGWVDQNSPVLLDEPVLHCMAKKYNRTPALIALRYQLQRGIVALNSTFNEEHIKENIQVFEFQLSSEDMKVLDGLNRNQRYVTALIFDGHPNFPFSDEY", "length": 297, "header": "tr|A0A9J7FMT9-1|A0A8C2QBZ3_CRIGR Computationally mapped isoform of Aldo-keto reductase family 1 member C21-like isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100770388 PE=3 SV=1 CANONICAL=A0A8C2QBZ3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FMT9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMT9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FMT9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMT9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770388", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770388", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6AYQ2-1", "protein_name": "Aldo-keto reductase family 1 member C21", "gene_name": "Akr1c21", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSKCHCVKLNDGHFIPVLGFGTAMPSELPKSKAKEVTKIAIDAGFHHFDSAFVYNTEDHVGEAIREKIANGTTRREDIFYTSKLWCTSLHPELVRSSLECSLKKLQLDYVDLYLIHFPMALKPGDENFPVDEHGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKYKPVCNQVECHLYLNQMKLLDFCKTNGIILVAYGVLGTQRYNGWVDQNSPVLLNEPVLSSMAKKYNQTPALIALRHQLQRGIVVLNTSLKEERIKENMKLSPEDMKVLDDLNRNLRYIAGGIFEGHPNFPFLDEY", "length": 318 }, "evidence": [ { "id": "A0A8C2QBZ3", "url": "https://omabrowser.org/oma/group/A0A8C2QBZ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91WR5-1", "protein_name": "Aldo-keto reductase family 1 member C21", "gene_name": "Akr1c21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSKCHCVILNDGNFIPVLGFGTALPLECPKSKAKELTKIAIDAGFHHFDSASVYNTEDHVGEAIRSKIADGTVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALKPGEENFPVDEHGKLIFDRVDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQMKLLDFCKSKDIVLVAYGVLGTQRYGGWVDQNSPVLLDEPVLGSMAKKYNRTPALIALRYQLQRGIVVLNTSLKEERIKENMQVFEFQLSSEDMKVLDGLNRNMRYIPAAIFKGHPNWPFLDEY", "length": 323 }, "evidence": [ { "id": "A0A8C2QBZ3", "url": "https://omabrowser.org/oma/group/A0A8C2QBZ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "17-beta-hydroxysteroid dehydrogenase (NADP+) activity", "id": "GO:0072582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072582", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ3" } ], "pmid": "" }, { "name": "androsterone dehydrogenase [NAD(P)+] activity", "id": "GO:0047023", "url": 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MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613664.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497800", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497800" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Exosc1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ4", "locus": {} } ], "crossref": [ { "id": "cd05791", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05791", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757484", "url": "https://www.ncbi.nlm.nih.gov/gene/100757484", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039771", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039771", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757484", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757484", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PMVPVGW", "url": "https://omabrowser.org/oma/group/PMVPVGW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QBZ4", "url": "https://www.orthodb.org/?gene=A0A8C2QBZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12686", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12686", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12686:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12686:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14382", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14382", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003497800", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497800", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QBZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QBZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLTKTSENGALPVVSVMRETESQLLPDVGAVVTCKVSSINSRFAKVHILYVGSTPLKNAFRGTIRKEDIRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGVQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT", "length": 195, "header": "tr|A0A8C2QBZ4-1|A0A8C2QBZ4_CRIGR Isoform 1 of Exosome complex component CSL4 OS=Cricetulus griseus OX=10029 GN=Exosc1 PE=3 SV=1 CANONICAL=A0A8C2QBZ4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QBZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ4/entry#A0A8C2QBZ4-1", "sequence": { "sequence": "MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLTKTSENGALPVVSVMRETESQLLPDVGAVVTCKVSSINSRFAKVHILYVGSTPLKNAFRGTIRKEDIRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGVQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT", "length": 195, "header": "tr|A0A8C2QBZ4-1|A0A8C2QBZ4_CRIGR Isoform 1 of Exosome complex component CSL4 OS=Cricetulus griseus OX=10029 GN=Exosc1 PE=3 SV=1 CANONICAL=A0A8C2QBZ4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757484", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757484", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B8A4H5-1", "protein_name": "Exosome complex component CSL4", "gene_name": "exosc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSPMKLCVPGERLCSTEDCIPGTGTYLRHGYIFASLAGYVLRKNEGEELPVISVVRETEAQLLPDVGAIVTCKVTSINPRFAKVHILYVGSTPLKDRFRGTIRREDVRATEKDKVETYKSFRPGDIVLAKVISLGDVQSNYLLTTAENELGVVVAHSEAGAQMVPVSWCEMQCPRTHSKEFRKVARVQPEYLQA", "length": 194 }, "evidence": [ { "id": "A0A8C2QBZ4", "url": "https://omabrowser.org/oma/group/A0A8C2QBZ4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0RDC9-1", "protein_name": "Exosome complex component CSL4", "gene_name": "Exosc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLTKTSENGALPVVSVMRETESQLLPDVGAVVTCKVSSINSRFAKVHILYVGSTPLKNAFRGTIRKEDIRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGVQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT", "length": 195 }, "evidence": [ { "id": "A0A8C2QBZ4", "url": "https://omabrowser.org/oma/group/A0A8C2QBZ4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54N99-1", "protein_name": "Exosome complex component CSL4", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQSSSNDIITPGQRLCKESDFISSEGTYVHKGYIYSSVLGFKHVIKRNIDTTNENNVNNSNNSNEIENNKDYIVVLKEKEPSVVPEIGSIVTVQVLRINPKLASVAILCVGTKALKETFNGIIRIQDVRATEIDKVEIYKSFRPGDIVLAQIVCL", "length": 156 }, "evidence": [ { "id": "A0A8C2QBZ4", "url": "https://omabrowser.org/oma/group/A0A8C2QBZ4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9DAA6-1", "protein_name": "Exosome complex component CSL4", "gene_name": "Exosc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKTSENGAVPVVSVMRETESQLLPDVGAVVTCKVSSINSRFAKVHILYVGSTPLKNAFRGTIRKEDIRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGVQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT", "length": 195 }, "evidence": [ { "id": "A0A8C2QBZ4", "url": "https://omabrowser.org/oma/group/A0A8C2QBZ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VKJ4-1", "protein_name": "Csl4", "gene_name": "Csl4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSEQQDETVVCLPGERLCRTEDSIVLGIGTYEQNGYIYASKSGIVNIEDSGDKCQVVSVHKPGFHLTIPATGDVVTARVLVTTPKFAKCAIFCVRNVLLESSYRGLLRKEDVRETEKDRVDIYKSFRPGDVILARVINQLEQSFLLTTAENELGVVIAYASDYRKTRVPMVPVGWSEMQCPQTTIKEPRKVAKVLPESSINAVK", "length": 204 }, "evidence": [ { "id": "A0A8C2QBZ4", "url": "https://omabrowser.org/oma/group/A0A8C2QBZ4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y3B2-1", "protein_name": "Exosome complex component CSL4", "gene_name": "EXOSC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETESQLLPDVGAIVTCKVSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT", "length": 195 }, "evidence": [ { "id": "A0A8C2QBZ4", "url": "https://omabrowser.org/oma/group/A0A8C2QBZ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ4" } ], "pmid": "" }, { "name": "nuclear exosome (RNase complex)", "id": "GO:0000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000176", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ4" } ], "pmid": "" }, { "name": "RNA catabolic process", "id": "GO:0006401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QBZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QBZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ4" }, { "id": "SM00316", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00316" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "S1 motif", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 147, "start_aa": "Asp", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QC03-1", "uniprot_ac": "A0A8C2QC03", "uniprot_id": "A0A8C2QC03_CRIGR", "mass": { "chemical_mass": 74491.0, "monoisotopic_mass": 74491.0 }, "refseq": { "ac": "XP_035305952", "name": "calpain-6 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305952" }, "gene_names": [ { "name": "Capn6", "type": "recommended", "evidence": [ { "id": "A0A8C2QC03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC03" } ] }, { "name": "Capn6", "type": "synonym", "evidence": [ { "id": "XP_035305952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305952" } ] } ], "protein_names": [ { "name": "Calpain-6", "type": "recommended", "evidence": [ { "id": "A0A8C2QC03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC03/entry#names_and_taxonomy" } ] }, { "name": "calpain-6 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305952" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305952", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305952" } ] }, { "annotation": "Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC03", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC03#function" }, { "database": "UniProtKB", "id": "ARBA00058712", "url": "https://www.uniprot.org/uniprotkb/ARBA00058712#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC03", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC03" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Capn6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC03", "locus": {} } ], "crossref": [ { "id": "cd00044", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00044", "database": "CDD", "categories": [ "Protein Classification" ] }, 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773921", "url": 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RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027287053", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287053" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC05" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lin37", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC05", "locus": {} } ], "crossref": [ { "id": "100754605", "url": "https://www.ncbi.nlm.nih.gov/gene/100754605", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028226", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028226", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754605", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754605", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SNVARWK", "url": "https://omabrowser.org/oma/group/SNVARWK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QC05", "url": "https://www.orthodb.org/?gene=A0A8C2QC05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7KCX8", "url": "https://www.orthodb.org/?gene=A0A9J7KCX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31336:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31336:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15306", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15306", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027287053", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287053", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QC05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QC05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCX8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFPVKVKVEKSEMEMAKARSQLDAVLQCLLDKSHMDRERLDEDAGKTPSDTHNKDCSIAASGKRPSARFPHQRRKKRREMDDGLAEGGPQRSNTYVIKLFDRSVDLAQFSENTPLYPICRAWMRNSPSVRERERERSPSSPLPPLPEDEEGSEVINSKSRDVYKLPPPTAPGPLGDACRSRIPSPLQPETQGTPDDEPSEPEPSPSTLIYRNMQRWKRIRQRWKEASHRNQLRYSESMKILREMYDRQ", "length": 248, "header": "tr|A0A8C2QC05-1|A0A8C2QC05_CRIGR Isoform 1 of Protein lin-37 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=Lin37 PE=4 SV=1 CANONICAL=A0A8C2QC05-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QC05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC05/entry#A0A8C2QC05-1", "sequence": { "sequence": "MFPVKVKVEKSEMEMAKARSQLDAVLQCLLDKSHMDRERLDEDAGKTPSDTHNKDCSIAASGKRPSARFPHQRRKKRREMDDGLAEGGPQRSNTYVIKLFDRSVDLAQFSENTPLYPICRAWMRNSPSVRERERERSPSSPLPPLPEDEEGSEVINSKSRDVYKLPPPTAPGPLGDACRSRIPSPLQPETQGTPDDEPSEPEPSPSTLIYRNMQRWKRIRQRWKEASHRNQLRYSESMKILREMYDRQ", "length": 248, "header": "tr|A0A8C2QC05-1|A0A8C2QC05_CRIGR Isoform 1 of Protein lin-37 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=Lin37 PE=4 SV=1 CANONICAL=A0A8C2QC05-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KCX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC05/entry#A0A9J7KCX8-1", "sequence": { "sequence": "MEMAKARSQLDAVLQCLLDKSHMDRERLDEDAGKTPSDTHNKDCSIAASGKRPSARFPHQRRKKRREMDDGLAEGGPQRSNTYVIKLFDRSVDLAQFSENTPLYPICRAWMRNSPSVRERERERSPSSPLPPLPEDEEGSEVINSKSRDVYKLPPPTAPGPLGDACRSRIPSPLQPETQGTPDDEPSEPEPSPSTLIYRNMQRWKRIRQRWKEASHRNQLRYSESMKILREMYDRQ", "length": 236, "header": "tr|A0A9J7KCX8-1|A0A8C2QC05_CRIGR Computationally mapped isoform of Protein lin-37 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=Lin37 PE=4 SV=1 CANONICAL=A0A8C2QC05-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754605", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754605", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A503-1", "protein_name": "Lin-37 DREAM MuvB core complex component", "gene_name": "Lin37", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFPVKVKVEKSEMEMAKARNQLDAVLQCLLEKSHMDRERLDEEAGKTLSDTHNKDCSIAATGKRPSARFPHQRRKKRREMDDGLAEGGPQRSNTYVIKLFDRSVDLAQFSENTPLYPICRAWMRNSPTVRERERSPGSPLPPLPEDGEGSEVINSKNRDVYKLPPPTAPAALGDACRSRIPSPLQPETQGTTDDEPSEPEPSPSTLIYRNMQRWKRIRQRWKEASHRNQLRYSESMKILREMYDRQ", "length": 246 }, "evidence": [ { "id": "A0A8C2QC05", "url": "https://omabrowser.org/oma/group/A0A8C2QC05/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RM63-1", "protein_name": "Lin-37 DREAM MuvB core complex component", "gene_name": "LIN37", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFPVKVKVEKSELEMAKARNQLDAVLQCLLEKSHMDRERLDEEARKTPSDAHNKDCSIAATGKRPSARFPHQRRKKRREMDDGLAEGGPQRSNAYVIKLFDRSVDLAQFSENTPLYPICRAWMRNSPSVRERERSPSSPLPPLPEDEEGSEVTNSKSRDVYKLPPPTAPGPPGDTCRSRIPSPLQPETQGAPDDEPSEPEPSPSTLIYRNMQRWKRIRQRWKEASHRNQLRYSESMKILREMYERQ", "length": 246 }, "evidence": [ { "id": "A0A8C2QC05", "url": "https://omabrowser.org/oma/group/A0A8C2QC05/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q1RMQ5-1", "protein_name": "Protein lin-37 homolog", "gene_name": "LIN37", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFPVKVKVEKSELEMAKARNQLDAVLQCLLEKSHMDRERLDEEPGKTSLDTHNKDCSITATGKRPSARFPHQRRKKRREMDEGLAEGGPQRSNTYVIKLFDRSVDLAQFSENTPLYPICRAWMRNSPTVRERERSPSSPLPPLPEDEEGSEVTNSKSRDVYKLPPPTAPGPPGDACRSRIPSPLQPETQGTPDDEPSEPEPSPSTLIYRNMQRWKRIRQRWKEASHRNQLRYSESMKILREMYERQ", "length": 246 }, "evidence": [ { "id": "A0A8C2QC05", "url": "https://omabrowser.org/oma/group/A0A8C2QC05/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96GY3-1", "protein_name": "Protein lin-37 homolog", "gene_name": "LIN37", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFPVKVKVEKSELEMAKARNQLDAVLQCLLEKSHMDRERLDEEAGKTPSDTHNKDCSIAATGKRPSARFPHQRRKKRREMDDGLAEGGPQRSNTYVIKLFDRSVDLAQFSENTPLYPICRAWMRNSPSVRERECSPSSPLPPLPEDEEGSEVTNSKSRDVYKLPPPTPPGPPGDACRSRIPSPLQPEMQGTPDDEPSEPEPSPSTLIYRNMQRWKRIRQRWKEASHRNQLRYSESMKILREMYERQ", "length": 246 }, "evidence": [ { "id": "A0A8C2QC05", "url": "https://omabrowser.org/oma/group/A0A8C2QC05/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D8N6-1", "protein_name": "Protein lin-37 homolog", "gene_name": "Lin37", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFPVKVKVEKSEMEMAKARNQLDAVLQCLLEKSHMDRERLDEEAGKTPLDTHNKDCSIAATGKRPSARFPHQRRKKRREMDDGLAEGGPQRSNTYVIKLFDRSVDLAQFSENTPLYPICRAWMRNSPTVRERERSPGSPLPPLPEDGEGSEVINSKNRDVYKLPPPTAPGPLGDACRSRIPSPLQPETEGTPDDEPSEPEPSPSTLIYRNMQRWKRIRQRWKEASHRNQLRYSESMKILREMYDRQ", "length": 246 }, "evidence": [ { "id": "A0A8C2QC05", "url": "https://omabrowser.org/oma/group/A0A8C2QC05/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC05" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC05" } ], "pmid": "" }, { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC05" } ], "pmid": "" }, { "name": "Myb complex", "id": "GO:0031523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031523", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC05" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC05", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC05" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QC06-1", "uniprot_ac": "A0A8C2QC06", "uniprot_id": "A0A8C2QC06_CRIGR", "mass": { "chemical_mass": 24538.0, "monoisotopic_mass": 24538.0 }, "refseq": { "ac": "XP_003500185", "name": "ropporin-1-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500185" }, "gene_names": [ { "name": "Ropn1l", "type": "recommended", "evidence": [ { "id": "A0A8C2QC06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC06" } ] }, { "name": "Ropn1l", "type": "synonym", "evidence": [ { "id": "XP_003500185", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500185" } ] } ], "protein_names": [ { "name": "Ropporin-1-like protein", "type": "recommended", "evidence": [ { "id": "A0A8C2QC06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC06/entry#names_and_taxonomy" } ] }, { "name": "ropporin-1-like protein", "type": "synonym", "evidence": [ { "id": "XP_003500185", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500185" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613775.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003500185", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500185" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC06" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ropn1l", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC06", "locus": {} } ], "crossref": [ { "id": "cd23019", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23019", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759891", "url": "https://www.ncbi.nlm.nih.gov/gene/100759891", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR047844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759891", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759891", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QWSSAYF", "url": "https://omabrowser.org/oma/group/QWSSAYF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QC06", "url": "https://www.orthodb.org/?gene=A0A8C2QC06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14952", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14952", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14952:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14952:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_003500185", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500185", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QC06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QC06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPVDVLQWSAGYFSALSRGDPLPVKDRIEMPVATQKTDTGLTQGLLKVLHKQCSHKQYVELKDLEKKWKNLCLPIEKFRAILELDPCDEKIEWIKFLALGCSSLGGSLKAAMKNVCEILTEDPEGGPARIPFDTFSYIYQYLSGLDPDHPPGERELFLATLREKSESRKNNMIGLSDFYLGKKT", "length": 217, "header": "tr|A0A8C2QC06-1|A0A8C2QC06_CRIGR Isoform 1 of Ropporin-1-like protein OS=Cricetulus griseus OX=10029 GN=Ropn1l PE=3 SV=1 CANONICAL=A0A8C2QC06-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QC06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC06/entry#A0A8C2QC06-1", "sequence": { "sequence": "MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPVDVLQWSAGYFSALSRGDPLPVKDRIEMPVATQKTDTGLTQGLLKVLHKQCSHKQYVELKDLEKKWKNLCLPIEKFRAILELDPCDEKIEWIKFLALGCSSLGGSLKAAMKNVCEILTEDPEGGPARIPFDTFSYIYQYLSGLDPDHPPGERELFLATLREKSESRKNNMIGLSDFYLGKKT", "length": 217, "header": "tr|A0A8C2QC06-1|A0A8C2QC06_CRIGR Isoform 1 of Ropporin-1-like protein OS=Cricetulus griseus OX=10029 GN=Ropn1l PE=3 SV=1 CANONICAL=A0A8C2QC06-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC06" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC06" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759891", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759891", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K0B7-1", "protein_name": "Ropporin-1-like protein", "gene_name": "Ropn1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPADVLQWSAGYFSALSRGDPLPVKDRIEMPVATQKTDTGLTQGLLKVLHKQCSHKQYVELADLEKKWKNLCLPVEKFRAIVDLDPSEDKMEWIKFLALGCSSLGGTLNTAMKNVCEILTSDPEGGPARIPFETFAYIYQYLSALDPEFSAVETETYLANLRDTSESRKNGMIGLSDFVIGKKPV", "length": 218 }, "evidence": [ { "id": "A0A8C2QC06", "url": "https://omabrowser.org/oma/group/A0A8C2QC06/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1MDV9-1", "protein_name": "Ropporin-1-like protein", "gene_name": "ROPN1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPADVLQWSAGYFSALSRGDPLPVKDRIEMPMATQKTDTGLTQGLLKVLHKQCSHKEYVDLADLEQKWKNLCLPVEKFRALLQLDPCEDKIEWIKFLALGCSMLGGSLNTAMKHLCEILTTDPEGGPARIPFGTFSYVYRYLSGLDSDIPESDTEAYLSSLKENARPIGPLTGGKEHTPSPQPRGVRCGLVV", "length": 225 }, "evidence": [ { "id": "A0A8C2QC06", "url": "https://omabrowser.org/oma/group/A0A8C2QC06/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BXU3-1", "protein_name": "Ropporin-1-like protein", "gene_name": "ROPN1L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPLPDTLFCAQQIKIPPELPDIMKQFTKAAIRTQPRDVLQWSAAYFTALSKGELLPVKERIETPSAKQKMDAGLTPGLLKVLHKQLSAKGTVSVAELKKKWKDLCLPEEQLEAILQLDIFDEEVEWMKILALGCSMLGESLLSSMKHACEILTQDPEGGAARIPYETFSFLYCYLASIDGDIPDEKIKAFLQKIKDDADRQSGMVLLRNFQSQPSTQF", "length": 218 }, "evidence": [ { "id": "A0A8C2QC06", "url": "https://omabrowser.org/oma/group/A0A8C2QC06/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LDE6-1", "protein_name": "Ropporin-1-like protein", "gene_name": "ROPN1L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPADVLQWSAGYFSALSRGDPLPVKDRIEMPMATQKTDTGLTQGLLKVLHKQCSHKEYVELADLEQKWKNLCLPIEKFKVLLQLDPCENKIEWIKFLALGCSMLGGSLNTAMKHLCEILTSDPEGGPARIPFEIFSYVYRYLSGLDKEIPASDTESYLSSLKDKVDSRKNGMVGLSDFFTLKKKI", "length": 218 }, "evidence": [ { "id": "A0A8C2QC06", "url": "https://omabrowser.org/oma/group/A0A8C2QC06/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q66IC9-1", "protein_name": "Ropporin-1-like protein", "gene_name": "ropn1l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPLSETMYCAQQINIPPALPNMLKQFTKAAIRTQPRDVLQWAADYFSALSKGQDLPVKKRLELPVATQKTDTGLTPGLLKILHQQLTSKETVTKDELLPKWKALHLPVEQLDTILALGNFSENINWMQFFALACSALGGSITSALKHACEILTEDPEGGPAQIPFHMFRSLYTYLAHLDGEIPEEQIDSFLHSLEGQAQSQGGMVQPSNFTSLHTAEK", "length": 218 }, "evidence": [ { "id": "A0A8C2QC06", "url": "https://omabrowser.org/oma/group/A0A8C2QC06/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q96C74-1", "protein_name": "Ropporin-1-like protein", "gene_name": "ROPN1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPADVLRWSAGYFSALSRGDPLPVKDRMEMPTATQKTDTGLTQGLLKVLHKQCHHKRYVELTDLEQKWKNLCLPKEKFKALLQLDPCENKIKWINFLALGCSMLGGSLNTALKHLCEILTDDPEGGPARIPFKTFSYVYRYLARLDSDVSPLETESYLASLKENIDARKNGMIGLSDFFFPKRKLLESIENSEDVGH", "length": 230 }, "evidence": [ { "id": "A0A8C2QC06", "url": "https://omabrowser.org/oma/group/A0A8C2QC06/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EQ00-1", "protein_name": "Ropporin-1-like protein", "gene_name": "Ropn1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPADVLQWSAGYFSALSRGDPLPVKDRIEMPVATQKTDTGLTQGLLKVLHKQCSHKQYVELADLEKKWKNLCLPVEKLRTILELDPCEDKIEWIKFLALGCSSLGRTLNTAMKNVCEILTSDPEGGPARIPFETFAYVYQYLSGLDPELPAVETENYLTSLRLMSESRKNGMIGLSDFFVGKKII", "length": 218 }, "evidence": [ { "id": "A0A8C2QC06", "url": "https://omabrowser.org/oma/group/A0A8C2QC06/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "radial spoke", "id": "GO:0001534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001534", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC06" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC06" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC06" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC06" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC06" } ], "pmid": "" }, { "name": "sperm capacitation", "id": "GO:0048240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048240", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC06" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QC10-1", "uniprot_ac": "A0A8C2QC10", "uniprot_id": "A0A8C2QC10_CRIGR", "mass": { "chemical_mass": 21094.0, "monoisotopic_mass": 21094.0 }, "refseq": { "ac": "XP_027284554", "name": "protease-associated domain-containing protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284554" }, "gene_names": [ { "name": "Pradc1", "type": "recommended", "evidence": [ { "id": "A0A8C2QC10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC10" } ] }, { "name": "Pradc1", "type": "synonym", "evidence": [ { "id": "XP_027284554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284554" } ] } ], "protein_names": [ { "name": "Protease-associated domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8C2QC10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC10/entry#names_and_taxonomy" } ] }, { "name": "Protease-associated domain-containing protein of 21 kDa", "type": "synonym", "evidence": [ { "id": "A0A8C2QC10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC10/entry#names_and_taxonomy" } ] }, { "name": "protease-associated domain-containing protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027284554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284554" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027284554", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284554" } ] }, { "annotation": "Plays a role in the modulation of physical activity and adiposity.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JWS6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JWS6#function" }, { "database": "UniProtKB", "id": "ARBA00059667", "url": "https://www.uniprot.org/uniprotkb/ARBA00059667#function" }, { "database": "UniProtKB", "id": "A0A8C2QC10", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC10#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC10", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC10" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", 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This record is derived from a genomic sequence (NW_003614134.1) and transcript sequence (JP063378.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007643996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643996" } ] }, { "annotation": "Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003615056.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003511254", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511254" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC49", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC49" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100761400", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC49", "locus": {} } ], "crossref": [ { "id": "cd15226", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15226", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761400", "url": "https://www.ncbi.nlm.nih.gov/gene/100761400", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761400", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761400", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LFYMSSM", "url": "https://omabrowser.org/oma/group/LFYMSSM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QC49", "url": "https://www.orthodb.org/?gene=A0A8C2QC49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003511254", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511254", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QC49", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QC49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC49-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMRTNHSAVSEFVLLGLSNSREIQIFLFFFFCLFYVSSLTGNFIIVVTVTSDPYLHSPMYFLLANLSVIDLIFCSIAAPKMICDLFRKQKVISFGGCISQIFFSHAVGGTEMVLLIAMAFDRYVAICKPLHYLTIMSPRMCLLILVAAWIVGLIHSSAQLAFVVNLPFCGPNILDSFYCDIPRLLKLACTDTYKLEFMVTANSGIISLVAFFLLIISYIFLLITVQKHSLGHSSKALSTLLAHIMVVVLFFGPLIFFYVCPAPSTHVDKFLAIFDAVLTPFLNPLIYTFRNRDMKIAIRKGFYQLLGFRKSL", "length": 312, "header": "tr|A0A8C2QC49-1|A0A8C2QC49_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100761400 PE=3 SV=1 CANONICAL=A0A8C2QC49-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QC49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC49/entry#A0A8C2QC49-1", "sequence": { "sequence": "MMRTNHSAVSEFVLLGLSNSREIQIFLFFFFCLFYVSSLTGNFIIVVTVTSDPYLHSPMYFLLANLSVIDLIFCSIAAPKMICDLFRKQKVISFGGCISQIFFSHAVGGTEMVLLIAMAFDRYVAICKPLHYLTIMSPRMCLLILVAAWIVGLIHSSAQLAFVVNLPFCGPNILDSFYCDIPRLLKLACTDTYKLEFMVTANSGIISLVAFFLLIISYIFLLITVQKHSLGHSSKALSTLLAHIMVVVLFFGPLIFFYVCPAPSTHVDKFLAIFDAVLTPFLNPLIYTFRNRDMKIAIRKGFYQLLGFRKSL", "length": 312, "header": "tr|A0A8C2QC49-1|A0A8C2QC49_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100761400 PE=3 SV=1 CANONICAL=A0A8C2QC49-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"evidence": [ { "id": "A0A8C2QC49", "url": "https://omabrowser.org/oma/group/A0A8C2QC49/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZII6-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f56", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFGANHSAVSEFVLLGLSNSWEAQIFLFFFSCLFYVSSLTGNFIIVVTVTSDPYLHSPMYFLLANLSVIDLIFCSIAAPKMICDLFRKQKVISFGGCISQVFFSHAVGGTEMVLLIAMAFDRYVAICKPLHYLSIMSPRMCLLILVAAWIIGLIHSSTQLAFVINLPFCGPNILDSFYCDIPRLIKLACTDTYKLEFMIAANSGFISLIAFFLLIISYVFLLNTVQKQSSGCSSKALSTLLAHIIVVVLFFGPLIFFYVWPAPSTHVDKFLAIFDAVLTPFLNPVIYTLRNRDMKIAIRKVFCQRLAL", "length": 308 }, "evidence": [ { "id": "A0A8C2QC49", "url": "https://omabrowser.org/oma/group/A0A8C2QC49/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC49", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC49" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC49", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC49" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC49", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC49" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QC63-1", "uniprot_ac": "A0A8C2QC63", "uniprot_id": "A0A8C2QC63_CRIGR", "mass": { "chemical_mass": 41407.0, "monoisotopic_mass": 41407.0 }, "refseq": { "ac": "XP_007639151", "name": "transmembrane protein adipocyte-associated 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639151" }, "gene_names": [ { "name": "Tpra1", "type": "recommended", "evidence": [ { "id": "A0A8C2QC63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC63" } ] }, { "name": "Tpra1", "type": "synonym", "evidence": [ { "id": "XP_007639151", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639151" } ] } ], "protein_names": [ { "name": "Integral membrane protein GPR175", "type": "recommended", "evidence": [ { "id": "A0A8C2QC63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC63/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein adipocyte-associated 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007639151", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639151" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 180 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613782.1) and transcript sequence (IACG01035070.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007639151", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639151" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC63", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC63" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tpra1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC63", "locus": {} } ], "crossref": [ { "id": "100768331", "url": "https://www.ncbi.nlm.nih.gov/gene/100768331", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768331", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768331", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DRWKSIN", "url": "https://omabrowser.org/oma/group/DRWKSIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QC63", "url": "https://www.orthodb.org/?gene=A0A8C2QC63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15876", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15876", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15876:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15876:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007639151", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639151", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QC63", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QC63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K042", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K042", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K042-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K042-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSLQEANGSTAWPPPTASNRPPTASNISEPHQCLLLLYEDIGSSRVRYWDLLLLIPNVLFFIFLLWKLPLARAKIRVTSSPIFITFYILVFVVALVGIARAVVSMTVSASDAATIADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDSHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERVSLPSRRSFYVYAGILATLNLLQGLGSALLCANIIEGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDEAEEPDMHLPQPYAVARREGIESTGPAGVSAASYSSTQFDSAGMAYLDDIASMPCHTGSINSTDSERWKAINA", "length": 376, "header": "tr|A0A8C2QC63-1|A0A8C2QC63_CRIGR Isoform 1 of Integral membrane protein GPR175 OS=Cricetulus griseus OX=10029 GN=Tpra1 PE=3 SV=1 CANONICAL=A0A8C2QC63-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QC63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC63/entry#A0A8C2QC63-1", "sequence": { "sequence": "MDSLQEANGSTAWPPPTASNRPPTASNISEPHQCLLLLYEDIGSSRVRYWDLLLLIPNVLFFIFLLWKLPLARAKIRVTSSPIFITFYILVFVVALVGIARAVVSMTVSASDAATIADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDSHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERVSLPSRRSFYVYAGILATLNLLQGLGSALLCANIIEGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDEAEEPDMHLPQPYAVARREGIESTGPAGVSAASYSSTQFDSAGMAYLDDIASMPCHTGSINSTDSERWKAINA", "length": 376, "header": "tr|A0A8C2QC63-1|A0A8C2QC63_CRIGR Isoform 1 of Integral membrane protein GPR175 OS=Cricetulus griseus OX=10029 GN=Tpra1 PE=3 SV=1 CANONICAL=A0A8C2QC63-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GJA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC63/entry#A0A9J7GJA0-1", "sequence": { "sequence": "MDSLQEANGSTAWPPPTASNRPPTASNISEPHQCLLLLYEDIGSSRVRYWDLLLLIPNVLFFIFLLWKLPLARAKIRVTSSPIFITFYILVFVVALVGIARAVVSMTVSASDAATIADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDSHLSAEDFNIYGHGGRQFWLVYSLVVILPKTPLKERVSLPSRRSFYVYAGILATLNLLQGLGSALLCANIIEGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDEAEEPDMHLPQPYAVARREGIESTGPAGVSAASYSSTQFDSAGMAYLDDIASMPCHTGSINSTDSERWKAINA", "length": 368, "header": "tr|A0A9J7GJA0-1|A0A9J7GJA0_CRIGR Computationally mapped isoform of Integral membrane protein GPR175 OS=Cricetulus griseus OX=10029 GN=Tpra1 PE=3 SV=1 CANONICAL=A0A8C2QC63-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K042-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC63/entry#A0A9J7K042-1", "sequence": { "sequence": "MDSLQEANGSTAWPPPTASNRPPTASNISEPHQCLLLLYEDIGSSRVRYWDLLLLIPNVLFFIFLLWKLPLARAKIRVTSSPIFITFYILVFVVALVGIARAVVSMTVSASDAATIADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDSHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERVSLPSRRSFYVYAGILATLNLLQGLGSALLCANIIEGLWASGQGRAAGPGRADLLPTTAVWMPLPSYTSASLHRSSMWPSSVASLAQSPRSFSPTNVKWMRLKSQTCTCHNPTQWLGVRA", "length": 343, "header": "tr|A0A9J7K042-1|A0A8C2QC63_CRIGR Computationally mapped isoform of Integral membrane protein GPR175 OS=Cricetulus griseus OX=10029 GN=Tpra1 PE=3 SV=1 CANONICAL=A0A8C2QC63-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 17, "start_aa": "Thr", "end_pos": 17, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr17", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K042", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K042" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K042", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K042" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768331", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768331", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AFL9-1", "protein_name": "Integral membrane protein GPR175", "gene_name": "TPRA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKHEEFNGEQFLFIFSRRQDIPVMMSMMRFSMSDNITRSTALVTALDNVTTLSPTTTQAINDTNITVPHKCLLLLYEDIGKSRVRYWDLLLLVPNVLFFMFLLWKLPSARAKIRVTSSPIFTTFYILVFVVALVGIARAVVSMTVSASDAATVADKILWEITRFFLLAIELSVVILGLAFGHLESKSSVKRVLAITTVLSLAYSVTQGTLEILYPDAHLSAEDFNIYGHGGRHFWLASSCFFFLVYSFVVILPKTPLKDRISLPSRKSFYVYAGILAVLNLVQGLGSALLCVDIIEGLCCVDATTFLYFSFFAPLIYVAFLKGFFGSEPKILFSYKCQVDEPEDVDVHLPHAYAVAKKEGMDSGFYSSTQIDTTAYLDDVASMPYHVGSINSIDSDRWKAINA", "length": 403 }, "evidence": [ { "id": "A0A8C2QC63", "url": "https://omabrowser.org/oma/group/A0A8C2QC63/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SPF4-1", "protein_name": "Integral membrane protein GPR175", "gene_name": "TPRA1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGGRGLRTGCWRDGHPGGGDLGQQSMALPPPLAPNISVPHRCLLLLYEDIGTSRVRYWDLLLLIPNVLFFIFLLWKLPFARAKIRVTSSPIFITFYILVFVVALVGIARAVVSMTVSTSDAATVADKILWEITRFFLLAIELSVVILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDAHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVVLPKTPLKERISLPSRRSFYVYAGILALLNLLQGLGSALLCADIIEGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDEAEEPDMHLPQPYAVARREGLEAAGAASTQFDSASGVAYLDDVASMPCHAGSINSTDSERWKAINA", "length": 377 }, "evidence": [ { "id": "A0A8C2QC63", "url": "https://omabrowser.org/oma/group/A0A8C2QC63/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q4V8X0-1", "protein_name": "Transmembrane protein adipocyte-associated 1 homolog", "gene_name": "tpra1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLETVTDVASFVHYGNTSVFPTADNSSEIIPDGESNISKPHRCLQVLYDDIGTSRVRYWDVMLLIPNVAFLVFLMWKLPSARAKIRLTSSPIFVAFYILVFVVAAVGITRAIVSMTVSTSSAATLIDKVLWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITAVLSLAYSITQGTLEIRFPDKHLSAKDFNIYGHGGRHFWLASSCFFFLVYSLIVILPKTPIRERISLPSKRSFYVYSGILALLNLVQGLGSALLCADIIEGLCCVDVTTFLYFSVFAPLIYVTFLKGFFGSEPKILFSYKSQIDEPEDSDVHLPHTSSSGLGRKDLDRGSYSSTQIDGSGAYLDDVVSGPFGGAHSINSVDSDRWRSINT", "length": 378 }, "evidence": [ { "id": "A0A8C2QC63", "url": "https://omabrowser.org/oma/group/A0A8C2QC63/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q791F6-1", "protein_name": "Transmembrane protein adipocyte-associated 1", "gene_name": "Tpra1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASLQEANGSTAWPPPTASNISEPHQCLLLLYEDIGSSRVRYWDLLLLIPNVLFFIFLLWKLPLARAKIRVTSSPIFITFYILVFVVALVGIARAVVSMTVSASDAATVADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDSHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERVSLPSRRSFYVYAGILATLNLLQGLGSALLCANIIVGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDEAEEPDMHLPQPYAVARREGIESAGPACASAANYSSTQFDSAGVAYLDDIASMPCHTGSINSTDSERWKAINA", "length": 369 }, "evidence": [ { "id": "A0A8C2QC63", "url": "https://omabrowser.org/oma/group/A0A8C2QC63/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86W33-1", "protein_name": "Transmembrane protein adipocyte-associated 1", "gene_name": "TPRA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTLEEVTWANGSTALPPPLAPNISVPHRCLLLLYEDIGTSRVRYWDLLLLIPNVLFLIFLLWKLPSARAKIRITSSPIFITFYILVFVVALVGIARAVVSMTVSTSNAATVADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDAHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERISLPSRRSFYVYAGILALLNLLQGLGSVLLCFDIIEGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDETEEPDVHLPQPYAVARREGLEAAGAAGASAASYSSTQFDSAGGVAYLDDIASMPCHTGSINSTDSERWKAINA", "length": 373 }, "evidence": [ { "id": "A0A8C2QC63", "url": "https://omabrowser.org/oma/group/A0A8C2QC63/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q94AH1-1", "protein_name": "Protein CANDIDATE G PROTEIN-COUPLED RECEPTOR 2", "gene_name": "CAND2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRVLSEIAESPFVISRLSPDSTATGGFIGGWVGKCHGFLHNTVLVLASILFVAYLAYEAKKSLSKLSNRRSYIMIAYYGFLWLVSLLNLAWCCLQAWECTPGKEVIWNLLTLFTTSGMLFLEVSLVAFLFQGNYASGAEALTRTFLISGLVIGLDLLLKAIYLFGFGVPLFIDNNEHIHKFKWGLWVIHKLLLAGIYGMIFFMYNSKWRERLPARPAFYKYITVMLALNGLSLFACALTANGAHFGLWLYGITSVCYHAFYLPLLYVTFLADFFQEEDLNLENVYYSEMKDAGFFDADWE", "length": 300 }, "evidence": [ { "id": "A0A8C2QC63", "url": "https://omabrowser.org/oma/group/A0A8C2QC63/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q99MU1-1", "protein_name": "Transmembrane protein adipocyte-associated 1", "gene_name": "Tpra1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLQEANGSTAWPPPTASNISEPHQCLLLLYEDIGSSRVRYWDLLLLIPNVLFFIFLLWKLPLARAKIRVTSSPIFITFYILVFVVALVGIARAVVSMTVSASDAATVADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDSHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERVSLPSRRSFYVYAGILATLNLLQGLGSALLCANIIVGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDEAEEPDMHLPQPYAVARREGIESAGPACASAANYSSTQFDSAGVAYLDDIASMPCHTGSINSTDSERWKAINA", "length": 369 }, "evidence": [ { "id": "A0A8C2QC63", "url": "https://omabrowser.org/oma/group/A0A8C2QC63/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC63", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC63" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC63", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC63" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 17 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 27, "end_pos": 29 }, { "start_pos": 364, "end_pos": 366 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QC75-1", "uniprot_ac": "A0A8C2QC75", "uniprot_id": "A0A8C2QC75_CRIGR", "mass": { "chemical_mass": 197114.0, "monoisotopic_mass": 197114.0 }, "refseq": { "ac": "XP_007645511", "name": "signal-induced proliferation-associated 1-like protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645511" }, "gene_names": [ { "name": "Sipa1l1", "type": "recommended", "evidence": [ { "id": "A0A8C2QC75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75" } ] }, { "name": "Sipa1l1", "type": "synonym", "evidence": [ { "id": "XP_007645511", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645511" } ] } ], "protein_names": [ { "name": "Signal-induced proliferation-associated 1-like protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2QC75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75/entry#names_and_taxonomy" } ] }, { "name": "signal-induced proliferation-associated 1-like protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_007645511", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645511" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614290.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007645511", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645511" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC75", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sipa1l1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75", "locus": {} } ], "crossref": [ { "id": "cd06745", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06745", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762052", "url": "https://www.ncbi.nlm.nih.gov/gene/100762052", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VWAIRAK", "url": "https://omabrowser.org/oma/group/VWAIRAK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QC75", "url": "https://www.orthodb.org/?gene=A0A8C2QC75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15711:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15711:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11881", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11881", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007645511", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645511", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QC75", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QC75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSLKRSQTERPVTADRASVVSTDGTPKVHTDDFYMRRFRSQNGSLGSSVMAAVGPPRSEGPHHITSTPGVPKMGVRARIADWPPRKENVKESSRSSQEIETSSCLESLSSKGSPVSQGSSVSLNSNDSAMLKSIQNTLKNKTGPAENMDSRFLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKSGPSLHREYGSTSSIDKQGTSGESFFDLLKGYKDDRSDRGPTPTKLSDFLITGGGKGSGFSLDVIDGPISQRENLRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEELGKSSDLEDNRSEDSVRPWTCPKCFAHYDVQSILFDLNEAVVNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFSSPMGSTEDLNSKGSLGMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFESTLSSHCTNAGVAVLEVPKESLMLHLDRVKRYTVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPEEMKENGSPYNYRIIFRTSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHAIPELNVQCLRLAFNTPKVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRAHNPCTESVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAELSSMGAIVWAVRAKDYNKAMEFDCLLGISNEFIVLIDQETRSVAFNCSCRDVIGWTSSDTSLKIFYERGECVSVESFISSEDIKEIVKRLQFVSKGCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEYKMNEGVSYEFKFPFRNNNKWQRNANKGAHSPQVPSQLQSPMTSRLNAGKGDGKMPPPERAGNIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCRNSPSNLSSSSETGSGGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDSIADQMEPTCHLPAVSKVLPAFRDSPSGRLIRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQGTSADSGIDTTSYGLSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVLSLADRTLETEGHGLDRKTESSLSLDLHSKSQGGSSPLTRENSTFSINDAGSHTSTMSSRHSASPVVFSSARSSPKEELHPTTTSQLAPSFSSASSSSSGPRTFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEMAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQKNFKFHALSSPQSPFPPTPTSRRALHRTLSDESIYSGQREHFFASRASLLDQALPNDVLFSSTYPSLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQETRRQPIPDPGLMPLPDTAADLDWSNLVDAAKAYEVQRASFFAASDENHRPLSAASNSDQLEEQALVQMKSYSSKESSPTLASKVDQLEGMLKMLREDLKKEKEDKAHLQAEVQHLREDNLRLQEESQNASDKLKKFTEWVFNTIDMS", "length": 1782, "header": "tr|A0A8C2QC75-1|A0A8C2QC75_CRIGR Isoform 1 of Signal-induced proliferation-associated 1-like protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Sipa1l1 PE=4 SV=1 CANONICAL=A0A8C2QC75-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QC75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75/entry#A0A8C2QC75-1", "sequence": { "sequence": "MTSLKRSQTERPVTADRASVVSTDGTPKVHTDDFYMRRFRSQNGSLGSSVMAAVGPPRSEGPHHITSTPGVPKMGVRARIADWPPRKENVKESSRSSQEIETSSCLESLSSKGSPVSQGSSVSLNSNDSAMLKSIQNTLKNKTGPAENMDSRFLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKSGPSLHREYGSTSSIDKQGTSGESFFDLLKGYKDDRSDRGPTPTKLSDFLITGGGKGSGFSLDVIDGPISQRENLRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEELGKSSDLEDNRSEDSVRPWTCPKCFAHYDVQSILFDLNEAVVNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFSSPMGSTEDLNSKGSLGMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFESTLSSHCTNAGVAVLEVPKESLMLHLDRVKRYTVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPEEMKENGSPYNYRIIFRTSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHAIPELNVQCLRLAFNTPKVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRAHNPCTESVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAELSSMGAIVWAVRAKDYNKAMEFDCLLGISNEFIVLIDQETRSVAFNCSCRDVIGWTSSDTSLKIFYERGECVSVESFISSEDIKEIVKRLQFVSKGCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEYKMNEGVSYEFKFPFRNNNKWQRNANKGAHSPQVPSQLQSPMTSRLNAGKGDGKMPPPERAGNIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCRNSPSNLSSSSETGSGGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDSIADQMEPTCHLPAVSKVLPAFRDSPSGRLIRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQGTSADSGIDTTSYGLSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVLSLADRTLETEGHGLDRKTESSLSLDLHSKSQGGSSPLTRENSTFSINDAGSHTSTMSSRHSASPVVFSSARSSPKEELHPTTTSQLAPSFSSASSSSSGPRTFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEMAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQKNFKFHALSSPQSPFPPTPTSRRALHRTLSDESIYSGQREHFFASRASLLDQALPNDVLFSSTYPSLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQETRRQPIPDPGLMPLPDTAADLDWSNLVDAAKAYEVQRASFFAASDENHRPLSAASNSDQLEEQALVQMKSYSSKESSPTLASKVDQLEGMLKMLREDLKKEKEDKAHLQAEVQHLREDNLRLQEESQNASDKLKKFTEWVFNTIDMS", "length": 1782, "header": "tr|A0A8C2QC75-1|A0A8C2QC75_CRIGR Isoform 1 of Signal-induced proliferation-associated 1-like protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Sipa1l1 PE=4 SV=1 CANONICAL=A0A8C2QC75-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1530, "start_aa": "Thr", "end_pos": 1530, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1530", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1552, "start_aa": "Thr", "end_pos": 1552, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1552", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 239, "start_aa": "Thr", "end_pos": 239, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr239", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 756, "start_aa": "Thr", "end_pos": 756, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr756", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC75", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC75", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M3G5-1", "protein_name": "Signal induced proliferation associated 1 like 1", "gene_name": "SIPA1L1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTSLKRSQTERPVATERASIVGADGTPKVHTDDFYMRRFRSQNGSLGSSVMAPVGPPRSEGSHHITSTPGVPKMGVRARIADWPPRKENVKESSRSSQEIETSSCLESMSSKSSPVSQGSSVSLNSSDSAMLKSIQNTLKSKTRPSENMDSRFLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKTGPSLHREYGSTSSIDKQGTSGESFFDLLKGYKDDKSDRGPSPTKLSDFLIAGGGKGSGFSLDVIDGPISQRENLRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEELGKSSDLEDNRSEDSVRPWTCPKCFAHYDVQSILFDLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFSSPMGSTEDLNSKGSLSMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFESTLSSHCTNAGVAVLEVPKENLVLHLDRVKRYIVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPEETKENGSPYNYRIIFRTSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHVIPELNVQCLRLAFNTPKVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYRDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRVHNPCTDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAELSSMGAIVWAVRAKDYNKAMEIDCLLGVSSEFIVLIEQETKSVVFNCSCRDVIGWTSTDASLKIFYERGECVSVESFVNNDDIKEIVKRLQFVSKGCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEYKMNEGVSYEFKFPFRNNNKWQRNANKGPHSPQVPSQVQSPMTSRLNAGKADGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQPCRNSPSSLSSSSETGSGGGTYRQKSMPEGFGISRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDSIADQMEPTCHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTEAELNSYNFLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLEAESHGLDRKTESSLSLDIHTKSQAGSSPLTRENPTFSINDAASHTSTMSSRHSASPVVFTSARSSPKEELHPATPPQLAPSFSSSSSSSSGPRTFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHPRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPDSQKNFKFHALSSPQSPFPTTPTSRRALHRTLSDESIYSGQREHFFTSRASLLDQALPNDVLFSSTYPSLPTSLPLRRPSYTLGMKSLHGEFSASDSSLTDVQETRRPPMPDPGLMPLPDAAADLDWSNLVDAAKAYEVQRASFFAASDENHRPLSAAASSDQLEDQALVQMKSYSSSKDSSPTLASKVDQLEGMLKMLREDLKKEKEDKAHLQAEVQHLREDNLRLQEESQNASDKLKKFTEWVFNTIDMS", "length": 1784 }, "evidence": [ { "id": "A0A8C2QC75", "url": "https://omabrowser.org/oma/group/A0A8C2QC75/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0ZPU5-1", "protein_name": "Signal induced proliferation associated 1 like 1", "gene_name": "SIPA1L1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTSLKRSQTERAVATGVSVGTDGTTKVHSDDFYMRRFRSQNGSLGSAVMAPVGPPRNESSHHVTSTPGVPKMGVRARIADWPPRKENIKETSRSSQDIETASCLDSMSSKSSPGSQGSSVNLNASDSVMLKSIQNTLKSKTRQSENLDSRFLTPDGYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTFKSGPSLHREYGSTSSIDKQGTSGESFFDLLKGYKDEKSDQRSPGTTKLSELLIASGSKGSGFSLDVIDGPITQRENLRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEGELGKSSDLEDNRSEDSVKPWTCPKCFAHYDVQSILFDLNEAAINRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFNSPMGSTEDLNSKGSLNMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFESTLSSHCTNAGVAVLEVPKENLILHLDRVKRYIVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPEEIKENGPQYNYRIIFRTSELMTLRGSVLEDAIPSTAKHCTARGLPLKEVLEYVVPELNIHCLRLAFNTPKVTEQLMKLDEQGLSYQLKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRVHGPCTDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAEIYSSGAIVWSVHAKDYSKGMEIDCLLGVSNEFVVLIEQDTKSVVFNCSCRDVIGWTSTDTNIKIFYERGECVSLESFISNIDDIKEIVKRLELVTKGCETVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIVPPYEDCTPRRSCSENYRMPVMEYKVNEGMSYEFKFPFRNNNKWQRNANKGQGPHVAQVPSQVQSPVPSRIGSGKGEGKMPPPERAANIPRSISSDGRPLESRRLSPGSDVYVTVSSIALARSQQCRNSPSNLSTSSETGSAGSTYRQKSMPEGFGISRRSPASIDRQSTQSDTGGSGKSTPSWQRSEDSIADQMEPTCHLPAVSKVLPSFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDSGERTEAELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSPRTGLTKEKVTPLWHSSSEVVSIADRTLEKESHIDRKAESSLSLDIHSKSQPASNPLTRENSAYSLSDAVSHTSTMSSRHSASPVVFTSARSSPKEELHSATSPQLAPSFSSSSSSSSGPRTFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEMAHPRLRASARDLRASPKRASKSTVEEDLKKLIDLDSPTPESQKNFKSHTLSCQSPFPSTPTTRRALQRTLSDESIYSGQRDHFFASRASLLDQAMPNDVLFTSTYPSLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQEQRRQPMPDPGLMPLPDSASDLDWSNLVDAAKAFEVQRASFFAVADENHRPVSAASSGDQAEDQLTAQIKPYTGKESPPTLASKVDQLEGLLKMLQEDLRKEKEDKANLQAEVQHLREDNLRLQEESQNATEKLKKFTEWVFNTIDMN", "length": 1785 }, "evidence": [ { "id": "A0A8C2QC75", "url": "https://omabrowser.org/oma/group/A0A8C2QC75/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O35412-1", "protein_name": "Signal-induced proliferation-associated 1-like protein 1", "gene_name": "Sipa1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSLKRSQTERPVTADRASVVSTDGTPKVHTDDFYMRRFRSQNGSLGSSVMAAVGPPRSEGPHHITSTPGVPKMGVRARIADWPPRKENVKESSRSSQEIETSSCLESLSSKGSPVSQGSSVSLNSNDSAMLKSIQNTLKNKTGPAESMDSRFLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKSGPSLHREYGSTSSIDKQGTSGESFFGLLKGYKDDRADRGPTPTKLSDFLITGGGKGSGFSLDVIDGPISQRENLRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEELGKSSDLEDNRSEDSVRPWTCPKCFAHYDVQSILFDLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSHSTSFSSPMGSTEDFNSKGSLGMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESTSFESALSSHCTNAGVAVLEVPKESLMLHLDRVRRYTVEHVDLGAYYYRKCFYQKEHWNYFGADENLGPVAVSIRREKPEDMKENGSPYNYRIIFRTSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHVIPELNVQCLRLAFNTPKVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNTPKVTEQFMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRAHNPCTESVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAELSSMGAIVWAVRAKDYNKAMEFDCLLGISNEFIVLIEQETKSVVFNCSCRDVIGWTSSDSSLKIFYERGECISVESFMSSEDIKEIVKRLQFVSKGCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLKQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEYKMNEGVSYEYKFPFRSNNKWQRNAGKGAHSPQVPLQLQSPMISRVNAGKGDGKMPLPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCRNSPSNLSSSSETGSGGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDSLADQMEPTCHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESDLNSYNYLQGTSADSGIDTASYGLSHGSTASLGASTSSPRSGPGKEKVAPLWHSSSEVLSLADRTLETEGHGMDRKTESSLSLDIHSKSQGGSSPLTRENSTFSINDATSHTSTMSSRHSASPVVFSSARSSPKEELHPTTSSQLAPSFSSSSSSSSGPRTFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQKNFKFHGLSSPQSPFPSTPTSRRALHRTLSDESIYSSQREHFFTSRASLLDQALPNDVFFSSTYPSLPKSLPLRRPSYTLGMKSLHGEFFASDSSLTDIQETRRQPIPDPGLMPLPDTASDLDWSNLVDAAKAYEVQRASFFAASDENHRPLSAASNSDQLEEQALVQMKSYSSSKDSSPTLASKVDQLEGMLKMLREDLKKEKEDKAHLQAEVEHLREDNLRLQEESQNASDKLKKFTEWVFNTIDMS", "length": 1822 }, "evidence": [ { "id": "A0A8C2QC75", "url": "https://omabrowser.org/oma/group/A0A8C2QC75/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43166-1", "protein_name": "Signal-induced proliferation-associated 1-like protein 1", "gene_name": "SIPA1L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSLKRSQTERPLATDRASVVGTDGTPKVHTDDFYMRRFRSQNGSLGSSVMAPVGPPRSEGSHHITSTPGVPKMGVRARIADWPPRKENIKESSRSSQEIETSSCLDSLSSKSSPVSQGSSVSLNSNDSAMLKSIQNTLKNKTRPSENMDSRFLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKTGPSLHREYGSTSSIDKQGTSGESFFDLLKGYKDDKSDRGPTPTKLSDFLITGGGKGSGFSLDVIDGPISQRENLRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEELGKSSDLEDNRSEDSVRPWTCPKCFAHYDVQSILFDLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFSSPMGSTEDLNSKGSLSMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFESTLSSHCTNAGVAVLEVPKENLVLHLDRVKRYIVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPDEMKENGSPYNYRIIFRTSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHVVPELNVQCLRLAFNTPKVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAELSSMGAIVWAVRAEDYNKAMELDCLLGISNEFIVLIEQETKSVVFNCSCRDVIGWTSTDTSLKIFYERGECVSVGSFINIEEIKEIVKRLQFVSKGCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEYKMNEGVSYEFKFPFRNNNKWQRNASKGPHSPQVPSQVQSPMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQKSFKFHALSSPQSPFPSTPTSRRALHRTLSDESIYNSQREHFFTSRASLLDQALPNDVLFSSTYPSLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQETRRQPMPDPGLMPLPDTAADLDWSNLVDAAKAYEVQRASFFAASDENHRPLSAASNSDQLEDQALAQMKPYSSSKDSSPTLASKVDQLEGMLKMLREDLKKEKEDKAHLQAEVQHLREDNLRLQEESQNASDKLKKFTEWVFNTIDMS", "length": 1804 }, "evidence": [ { "id": "A0A8C2QC75", "url": "https://omabrowser.org/oma/group/A0A8C2QC75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5TYS4-1", "protein_name": "Signal-induced proliferation-associated 1-like protein 1", "gene_name": "sipa1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSLKRSQTERSVGGSVPASDEFYTRRLRLPNGGAPPPRSESTHLTGTPGVPKMGVRARVADWPPRKDGGSGGSGGSGGSSGSGGGGGGGGGGGGNGGGVWHITVETDSPSTTTGSAQSNLSSKLGHLISPQDSSMLRNIHNTLKNKMQSKGKDNRFLSPDGYLGSPRKGMRRIRQRSNSDITISELDGDGSEGWSFSGWTPMHREYGSTSSIDKHGVSGESFFDMLKGYTTDAPDQRSPAPEKLSELLTVAHKQTALDLPDGPLGPPRGSPASRLKEREKQMKRRSKSETGGESIFRKLRSVKAEGDSSRAGSDAEDGKSDDLGPPPKPWVCQKGFAHFDVQSILFDLNEVVQSRQSAAKRKNTTTGASAAAAASASNTSSLSSTQSGAYGSPCGSQEELSVKDGPSLDSGDDKSNDLVLSCPCFRNEIGGEGERNISPSKQGSIGSGASSSSRDEEGSPERAPNTHFSNAGVAVLEAPKDGKSLHHDRGKSNILEHVDLGAYYYRKNFYLREHWNYLGVDETLGPVAVSIRREKLEDHKEHGQQYNYRIIFRTSELTTIRGSILEDAVPSTSKHGLARGLPLKEVLDYLVPELNAHCLRLALNTPKVTEQLMKLDEQGLSFQLKVGVMYCQAGQSSEEEMYNNETAGPALEEFLQLLGERVRLKGFSKYRAQLDTKTDSTGTHSLYTTFKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAKPFSPKNIRSHFQHVFVVVRALNPCTENACYRVAVARSRDVPAFGPPIPEDATFPKSTVFRDFLLAKVINAENAAHKSDKFRAMATRTRQEYLRDLAERHVTSTPIDPSGKFPFISLAHKRKEKTRPYLGAELRSPGAITWPVYAEDHGAGGELEALLAISNDFLVLVDPEAKAVVFNCAVRDVIGWTLGSPASMKIYYERGENISLRSMNNNTEDFREVVKRLEHLTKGCETSEMTLRRNGLGQLGFHVNYEGIVAEVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIIPPHEDATPRRGCSELHRMPVVEYKGSNESGSFEYKFPFRSNNNKWQRTSSSPQQSLTASPQSHSGTPNRAVSLGASMGKTLSAERPERAAAIPRSVSSDGRPLDSKRMSPGSENYALTSSLMLGRSQHNRSSPSNLSCSSDTGSGSSAHWRQKSMPEGFAHNRHSPLPPERQMAAEGGSSGKSTPSWPRVEDSSDRPPSDAPVTKSSSSYSGGPRIQRQEQVIHLSPKKGSQSEGPYSHSSSNTLSSTTSSGGHSDDKWYDLGSGGMGDQPESEPNGLGGGGYLQGASADSGIDTTSYGPTTHGSSSSLLAVGSAGARERAPSPWHSPTDGGRRVLERSPPAAESPVSPADGPPTTRSPPTHLLVRDGSTYSLSDMASYSSNRHSVSPAVMSSSHSSPREESSSATSPSSSSSQSSVSPGPKSFYPRQGATSKYLIGWRKPGSTINSVDFGDTRKRPQGEGTDLGSSQSRPSLRDLHSPQAMCKSTVDDDMKKLIITPESPPSIKHKEKLSSSGPSSSGRRSLHRTLSDESIYRGQRLPSLGDSVLEQALASDVLFSCSTLPRSPTTRGAPLRRPSYKMGIKMHGDLSASDTSLADLHDRQRLPPPELGLMPLPDTDTDSGLDWTHLVDVANAFEGERRPQRMQRGFMFSSQDVSHRGETSLSLQHLDLQPVPHTRLSPSEGPSSYGGKVSQLEALVKMLQEDLKKEREEKLKLQAQIKRLWEDNQRLQEESQSSAAKLKKFTEWVFNTIDLN", "length": 1794 }, "evidence": [ { "id": "A0A8C2QC75", "url": "https://omabrowser.org/oma/group/A0A8C2QC75/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8C0T5-1", "protein_name": "Signal-induced proliferation-associated 1-like protein 1", "gene_name": "Sipa1l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKRSQTERPVTADRASVVSTDGAPKVHTDDFYMRRFRSQNGSLGSSVMAAVGPPRSEGPHHITSTPGVPKMGVRARIADWPPRKENVKESSRSSQEIETSSCLESLSSKGSPVSQGSSVSLNSNDSAMLKSIQNTLKNKTGPAESMDSRFLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKSGPSLHREYGSTSSIDKQGTSGDSFFDLLKGYKDDRSDRGPTPTKLSDFLITGGGKGSGFSLDVIDGPISQRENLRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEELGKSSDLEDNRSEDSVRPWTCPKCFAHYDVQSILFDLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFSSPMGSTEDLNSKGSLGMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESTSFESALSSHCTNAGVAVLEVPKESLMLHLDRVKRYTVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPEDMKENGSPYNYRIIFRTSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHVIPELNVQCLRLAFNTPKVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRAHNPCTESVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAELSSMGAIVWAVRAKDYNKAMEFDCLLGISSEFIVLIEQETKSVAFNCSCRDVIGWTSSDTSLKIFYERGECVSVESFISGEDIKEIVRRLQFVSKGCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEYQMNEGISYEFKFPFRNNNKWQRNASKGAHSPQVPSQLQSPMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCRNSPSNLSSSSETGSGGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDISGSGKSTPSWQRSEDSLADQMEPTCHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESDLNSYNYLQGTSADSGIDTASYGPSHGSTASLGASTSSPRSGPGKEKVAPLWHSSSEVLSLADRTLETEGHGMDRKAESSLSLDIHSKSQGGSSPLSRENSTFSINDAASHTSTMSSRHSASPVVFSSARSSPKEELHPTASSQLAPSFSSSSSSSSGPRTFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLQASPKPTSKSTIEEDLKKLIDLESPTPESQKNFKFHALSSPQSPFPTTPTSRRALHRTLSDESIYSSQREHFFTSRASLLDQALPNDVLFSSTYPSLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQETRRQPIPDPGLMPLPDAASDLDWSNLVDAAKAYEVQRASFFAASDENHRPLSAASNSDQLEEQALVQMKSYSSKDPSPTLASKVDQLEGMLKMLREDLKKEKEDKAQLQAEVEHLREDNLRLQEESQNASDKLKKFTEWVFNTIDMS", "length": 1782 }, "evidence": [ { "id": "A0A8C2QC75", "url": "https://omabrowser.org/oma/group/A0A8C2QC75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of axonogenesis", "id": "GO:0050770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050770", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC75", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75" } ], "pmid": "" }, { "name": "ephrin receptor signaling pathway", "id": "GO:0048013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048013", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC75", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75" } ], "pmid": "" }, { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC75", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC75", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75" } ], "pmid": "" }, { "name": "ephrin receptor binding", "id": "GO:0046875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046875", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC75", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC75", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC75", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QC75", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1152, "end_pos": 1154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1272, "end_pos": 1274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1390, "end_pos": 1392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1763, "end_pos": 1765, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 820, "end_pos": 822, "annotation": "n_glycosylation_sequon" }, { "start_pos": 898, "end_pos": 900, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QC75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 953, "end_pos": 1017, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2QC75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC75" }, { "id": "PS50085", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50085" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rap-GAP", "eco_id": "ECO_0000259", "start_pos": 599, "end_pos": 816, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 239, 756, 1530, 1552 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1152, "end_pos": 1154 }, { "start_pos": 1272, "end_pos": 1274 }, { "start_pos": 127, "end_pos": 129 }, { "start_pos": 1390, "end_pos": 1392 }, { "start_pos": 141, "end_pos": 143 }, { "start_pos": 1763, "end_pos": 1765 }, { "start_pos": 316, "end_pos": 318 }, { "start_pos": 358, "end_pos": 360 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 529, "end_pos": 531 }, { "start_pos": 631, "end_pos": 633 }, { "start_pos": 820, "end_pos": 822 }, { "start_pos": 898, "end_pos": 900 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "A0A8C2QCA0", "uniprot_id": "A0A8C2QCA0_CRIGR", "mass": { "chemical_mass": 59758.0, "monoisotopic_mass": 59758.0 }, "refseq": { "ac": "XP_027256633", "name": "glycerol kinase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256633" }, "gene_names": [ { "name": "LOC100764600", "type": "recommended", "evidence": [ { "id": "A0A8C2QCA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA0" } ] }, { "name": "LOC100764600", "type": "synonym", "evidence": [ { "id": "XP_027256633", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256633" } ] } ], "protein_names": [ { "name": "glycerol kinase", "type": "recommended", "evidence": [ { "id": "A0A8C2QCA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA0/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.30", "type": "synonym", "evidence": [ { "id": "A0A8C2QCA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA0/entry#names_and_taxonomy" } ] }, { "name": "glycerol kinase", "type": "synonym", "evidence": [ { "id": "XP_027256633", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256633" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027256633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256633" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCA0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100764600", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA0", "locus": {} } ], "crossref": [ { "id": "cd07792", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07792", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764600", "url": "https://www.ncbi.nlm.nih.gov/gene/100764600", "database": "GeneID", "categories": [ 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"MADAEKAVLGPLVGAIDQGTSSTRFLVFNPKTADLLNYHQVQIKQEFPKEGWVEEDPKEILESVYDCIEKTCEKLGQQSIDVSNIKAIGVTNQRETTIVWDKVTGEPLYNAVVWLDLRTQSTVESLNKSISVSNNFVKTKTGLPISTYFSAVKLHWLINNVRKVQKAIEDGRALFGTVDSWLIWNMTGGVQGGVHCTDVTNASRTMLFNIHSLQWDEELCNFFGIPMSILPRIRSSSEIYGLMKTGALEGVPISGCLGDQSAALVGQLCLQDGQAKNTYGTGCFLLCNTGQKCVTSEHGLLTTVAYKLGREEPVYYALEGSVAIAGAVVSWLKDNIQIIKASKEIENLAEKVGTSYGCYFVPAFSGLYAPYWDPSARGIICGLTQFTNKCHIAFAALEAVCFQAREILDAMNRDCGIPLTHLQVDGGMTENKILMQLQADILCIPVVKPAMPETTALGAAMAAGAAEGVSVWSLDPKDLSLVQMEKFEPQINAEESEVRYSTWKQAVMKSMGWVMTETVEPSIFSSLSLGIYVVSSMVILIGARYI", "length": 546, "header": "tr|A0A8C2QCA0-1|A0A8C2QCA0_CRIGR Isoform 1 of glycerol kinase OS=Cricetulus griseus OX=10029 GN=LOC100764600 PE=3 SV=1 CANONICAL=A0A8C2QCA0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QCA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA0/entry#A0A8C2QCA0-1", "sequence": { "sequence": "MADAEKAVLGPLVGAIDQGTSSTRFLVFNPKTADLLNYHQVQIKQEFPKEGWVEEDPKEILESVYDCIEKTCEKLGQQSIDVSNIKAIGVTNQRETTIVWDKVTGEPLYNAVVWLDLRTQSTVESLNKSISVSNNFVKTKTGLPISTYFSAVKLHWLINNVRKVQKAIEDGRALFGTVDSWLIWNMTGGVQGGVHCTDVTNASRTMLFNIHSLQWDEELCNFFGIPMSILPRIRSSSEIYGLMKTGALEGVPISGCLGDQSAALVGQLCLQDGQAKNTYGTGCFLLCNTGQKCVTSEHGLLTTVAYKLGREEPVYYALEGSVAIAGAVVSWLKDNIQIIKASKEIENLAEKVGTSYGCYFVPAFSGLYAPYWDPSARGIICGLTQFTNKCHIAFAALEAVCFQAREILDAMNRDCGIPLTHLQVDGGMTENKILMQLQADILCIPVVKPAMPETTALGAAMAAGAAEGVSVWSLDPKDLSLVQMEKFEPQINAEESEVRYSTWKQAVMKSMGWVMTETVEPSIFSSLSLGIYVVSSMVILIGARYI", "length": 546, "header": "tr|A0A8C2QCA0-1|A0A8C2QCA0_CRIGR Isoform 1 of glycerol kinase OS=Cricetulus griseus OX=10029 GN=LOC100764600 PE=3 SV=1 CANONICAL=A0A8C2QCA0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "glycerol catabolic process", "id": "GO:0019563", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019563", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCA0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA0" } ], "pmid": "" }, { "name": "glycerol-3-phosphate biosynthetic process", "id": "GO:0046167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046167", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCA0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA0" } ], "pmid": "" }, { "name": "triglyceride metabolic process", "id": "GO:0006641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006641", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCA0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial outer 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0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QCA3-1", "uniprot_ac": "A0A8C2QCA3", "uniprot_id": "A0A8C2QCA3_CRIGR", "mass": { "chemical_mass": 26856.0, "monoisotopic_mass": 26856.0 }, "refseq": { "ac": "XP_003496288", "name": "STARD3 N-terminal-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496288" }, "gene_names": [ { "name": "Stard3nl", "type": "recommended", "evidence": [ { "id": "A0A8C2QCA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA3" } ] }, { "name": "Stard3nl", "type": "synonym", "evidence": [ { "id": "XP_003496288", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496288" } ] } ], "protein_names": [ { "name": "STARD3 N-terminal-like protein", "type": "synonym", "evidence": [ { "id": "XP_003496288", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496288" }, { "id": "A0A8C2QCA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613616.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003496288", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496288" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCA3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Stard3nl", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA3", "locus": {} } ], "crossref": [ { "id": "100767628", "url": "https://www.ncbi.nlm.nih.gov/gene/100767628", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019498", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019498", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767628", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767628", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HWWAVAI", "url": "https://omabrowser.org/oma/group/HWWAVAI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QCA3", "url": "https://www.orthodb.org/?gene=A0A8C2QCA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46121:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46121:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10457", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10457", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003496288", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496288", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QCA3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QCA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNHQPEDMENTLTGSQSSHASLRDIHPINPAQLMARIESYEGREKKGISDVRRTFCLFVTFDLLFVTLLWIIELNVNGGIENTLKREVIHYDYYSSYFDIFLLAVFRFKVLILGYAVCRLRHWWAIALTTAVTSAFLLAKVILSKLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRLLLVQDASERAVLIPAGLSDGQFYSPPESEAGSEEEAEEKQDSEKPLLEL", "length": 235, "header": "tr|A0A8C2QCA3-1|A0A8C2QCA3_CRIGR Isoform 1 of STARD3 N-terminal-like protein OS=Cricetulus griseus OX=10029 GN=Stard3nl PE=3 SV=1 CANONICAL=A0A8C2QCA3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QCA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA3/entry#A0A8C2QCA3-1", "sequence": { "sequence": "MNHQPEDMENTLTGSQSSHASLRDIHPINPAQLMARIESYEGREKKGISDVRRTFCLFVTFDLLFVTLLWIIELNVNGGIENTLKREVIHYDYYSSYFDIFLLAVFRFKVLILGYAVCRLRHWWAIALTTAVTSAFLLAKVILSKLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRLLLVQDASERAVLIPAGLSDGQFYSPPESEAGSEEEAEEKQDSEKPLLEL", "length": 235, "header": "tr|A0A8C2QCA3-1|A0A8C2QCA3_CRIGR Isoform 1 of STARD3 N-terminal-like protein OS=Cricetulus griseus OX=10029 GN=Stard3nl PE=3 SV=1 CANONICAL=A0A8C2QCA3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCA3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCA3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767628", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767628", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JT75-1", "protein_name": "STARD3 N-terminal like", "gene_name": "Stard3nl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNHLPEDMENTLTGSQSSHASLRDIHSINPGQLMARIESYEGREKKGISDVRRTFCLFVTFDLLFVTLLWIIELNVNGGIENTLKKEVAHYDYYSSYFDIFLLAVFRFKVLILGYAVCRLRHWWAIALTTAVTSAFLLAKVILSKLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRLLLVQDASERAALIPAGLSDGQFYSPPESEAGSEEEAEEKQDSEKPLLEL", "length": 235 }, "evidence": [ { "id": "A0A8C2QCA3", "url": "https://omabrowser.org/oma/group/A0A8C2QCA3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A1L1RKF5-1", "protein_name": "STARD3 N-terminal like", "gene_name": "STARD3NL", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNRVPNDAENAHSSSVESCPSLRDVHSINPTHLMARIESYDVREKKGISDVRRTFCLFVTFDLLFITLLWIIELNVKGGIETTLKKEVLHYDYSSSYFDIFLLAVFRFKVLILAYAMCRLRHWWAIAFTTAVTSAFLLAKVIISQLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRFLIAQGASERAALLHPGVLSDGQFYSPPESVAGSDEDSEEKQDSEKPVV", "length": 234 }, "evidence": [ { "id": "A0A8C2QCA3", "url": "https://omabrowser.org/oma/group/A0A8C2QCA3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O95772-1", "protein_name": "STARD3 N-terminal-like protein", "gene_name": "STARD3NL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNHLPEDMENALTGSQSSHASLRNIHSINPTQLMARIESYEGREKKGISDVRRTFCLFVTFDLLFVTLLWIIELNVNGGIENTLEKEVMQYDYYSSYFDIFLLAVFRFKVLILAYAVCRLRHWWAIALTTAVTSAFLLAKVILSKLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRLLIVQDASERAALIPGGLSDGQFYSPPESEAGSEEAEEKQDSEKPLLEL", "length": 234 }, "evidence": [ { "id": "A0A8C2QCA3", "url": "https://omabrowser.org/oma/group/A0A8C2QCA3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DCI3-1", "protein_name": "STARD3 N-terminal-like protein", "gene_name": "Stard3nl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNHLPEHMENTLTGSQSSHASLRDIHSINPAQLMARIESYEGREKKGISDVRRTFCLFVTFDLLFVTLLWIIELNVNGGIENTLKKEVIHYDYYSSYFDIFLLAVFRFKVLILGYAVCRLRHWWAIALTTAVTSAFLLAKVILSKLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRLLLVQDASERAALIPAGLSDGQFYSPPESEAGSEEEAEEKQESEKPLLEL", "length": 235 }, "evidence": [ { "id": "A0A8C2QCA3", "url": "https://omabrowser.org/oma/group/A0A8C2QCA3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCA3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA3" } ], "pmid": "" }, { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCA3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCA3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": 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"pmid": "" }, { "name": "vesicle tethering to endoplasmic reticulum", "id": "GO:0099044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099044", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCA3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QCA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCA3" }, { "id": "PS51439", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51439" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MENTAL", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 218, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QCD3-1", "uniprot_ac": "A0A8C2QCD3", "uniprot_id": "A0A8C2QCD3_CRIGR", "mass": { "chemical_mass": 48272.0, "monoisotopic_mass": 48272.0 }, "refseq": { "ac": "XP_035305430", "name": "carbohydrate sulfotransferase 8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305430" }, "gene_names": [ { "name": "LOC113837179", "type": "recommended", "evidence": [ { "id": "A0A8C2QCD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCD3" } ] }, { "name": "LOC113837179", "type": "synonym", "evidence": [ { "id": "XP_035305430", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305430" } ] } ], "protein_names": [ { "name": "Carbohydrate sulfotransferase", "type": "recommended", "evidence": [ { "id": "A0A8C2QCD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCD3/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "A0A8C2QCD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCD3/entry#names_and_taxonomy" } ] }, { "name": "carbohydrate sulfotransferase 8", "type": "synonym", "evidence": [ { "id": "XP_035305430", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305430" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305430", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305430" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCD3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCD3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113837179", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCD3", "locus": {} } ], "crossref": [ { "id": "113837179", "url": "https://www.ncbi.nlm.nih.gov/gene/113837179", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113837179", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837179", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QCD3", "url": "https://www.orthodb.org/?gene=A0A8C2QCD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12137", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12137", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12137:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12137:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305430", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305430", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QCD3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QCD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPRLGTMRLACMFSSILLFGAAGLLLFISLQDPVELSPEQVPGMKFSIRPQHDGHLRTPTERVTRDSPSGSPRGLQLQAPAQPGLPAKAKAAGSPVRLRQRRRRLLIKKMPAAAGPVRGNHSSETLVQPRAHTAADARWASLQRSQQERKRVMREACAKYRASSSGGSSSRKAVTARHVSRVFVEDRHRVLYCEVPKAGCSNWKRVLMVLAGLASSTADIQHNTVHYGSALKRLDTFDRQGIAHRLSTYTKMLFVREPFERLVSAFRDKFEHPNSYYHPVFGKAILARYRANASREALRTGSGVRFPEFIQYLLDVHRPVGMDIHWDHVSRLCSPCLIDYDFVGKFESMEDDANFFLHLIRAPGNLTFPRFKDRHSQEARTTSRITRDYFAQLSSLQRQRTYDFYYMDYLMFNYSKPFSDLY", "length": 423, "header": "tr|A0A8C2QCD3-1|A0A8C2QCD3_CRIGR Isoform 1 of Carbohydrate sulfotransferase OS=Cricetulus griseus OX=10029 GN=LOC113837179 PE=3 SV=1 CANONICAL=A0A8C2QCD3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QCD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCD3/entry#A0A8C2QCD3-1", "sequence": { "sequence": "MTPRLGTMRLACMFSSILLFGAAGLLLFISLQDPVELSPEQVPGMKFSIRPQHDGHLRTPTERVTRDSPSGSPRGLQLQAPAQPGLPAKAKAAGSPVRLRQRRRRLLIKKMPAAAGPVRGNHSSETLVQPRAHTAADARWASLQRSQQERKRVMREACAKYRASSSGGSSSRKAVTARHVSRVFVEDRHRVLYCEVPKAGCSNWKRVLMVLAGLASSTADIQHNTVHYGSALKRLDTFDRQGIAHRLSTYTKMLFVREPFERLVSAFRDKFEHPNSYYHPVFGKAILARYRANASREALRTGSGVRFPEFIQYLLDVHRPVGMDIHWDHVSRLCSPCLIDYDFVGKFESMEDDANFFLHLIRAPGNLTFPRFKDRHSQEARTTSRITRDYFAQLSSLQRQRTYDFYYMDYLMFNYSKPFSDLY", "length": 423, "header": "tr|A0A8C2QCD3-1|A0A8C2QCD3_CRIGR Isoform 1 of Carbohydrate sulfotransferase OS=Cricetulus griseus OX=10029 GN=LOC113837179 PE=3 SV=1 CANONICAL=A0A8C2QCD3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035299081", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299081" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCH0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100764921", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCH0", "locus": {} } ], "crossref": [ { "id": "cd05846", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05846", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764921", "url": "https://www.ncbi.nlm.nih.gov/gene/100764921", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764921", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764921", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QCH0", "url": "https://www.orthodb.org/?gene=A0A8C2QCH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46841", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46841", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46841:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46841:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035299081", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299081", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QCH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QCH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSLVFRRPFCHLSIYSLIWGMAAVALVTAQVEVVTQDERKLLHTPASLRCSLKQSQEPLIVTWQKKKAVSPENMVTYSKTHGVVVQPAYRDRVNITELGLWNTSITFWNTTLDDEGCYMCLFNTFVSGKISGTACLTLYVQPIVFLHYNYFEDHLNITCSATARPAPAIAWKGTGTGIENSTESHFHSNGTTSVTSILRVKDPKSQIGKEVICQVIYLGTVIDYKQSLDKGFWFSVPLLLSIVSLVILLVLISILLYWKRHRNQERGESSQGMQRMK", "length": 278, "header": "tr|A0A8C2QCH0-1|A0A8C2QCH0_CRIGR Isoform 1 of OX-2 membrane glycoprotein OS=Cricetulus griseus OX=10029 GN=LOC100764921 PE=4 SV=1 CANONICAL=A0A8C2QCH0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QCH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCH0/entry#A0A8C2QCH0-1", "sequence": { "sequence": "MGSLVFRRPFCHLSIYSLIWGMAAVALVTAQVEVVTQDERKLLHTPASLRCSLKQSQEPLIVTWQKKKAVSPENMVTYSKTHGVVVQPAYRDRVNITELGLWNTSITFWNTTLDDEGCYMCLFNTFVSGKISGTACLTLYVQPIVFLHYNYFEDHLNITCSATARPAPAIAWKGTGTGIENSTESHFHSNGTTSVTSILRVKDPKSQIGKEVICQVIYLGTVIDYKQSLDKGFWFSVPLLLSIVSLVILLVLISILLYWKRHRNQERGESSQGMQRMK", "length": 278, "header": "tr|A0A8C2QCH0-1|A0A8C2QCH0_CRIGR Isoform 1 of OX-2 membrane glycoprotein OS=Cricetulus griseus OX=10029 GN=LOC100764921 PE=4 SV=1 CANONICAL=A0A8C2QCH0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027287065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287065" } ] }, { "annotation": "Converts proline to delta-1-pyrroline-5-carboxylate.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCL8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCL8#function" }, { "database": "UniProtKB", "id": "RU364054", "url": "https://www.uniprot.org/uniprotkb/RU364054#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCL8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCL8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Prodh2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCL8", "locus": {} } ], "crossref": [ { "id": "100773901", "url": "https://www.ncbi.nlm.nih.gov/gene/100773901", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773901", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773901", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QCL8", "url": "https://www.orthodb.org/?gene=A0A8C2QCL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13914", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13914", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13914:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13914:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027287065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287065", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "23784", "url": "https://www.rhea-db.org/rhea/23784", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "52512", "url": "https://www.rhea-db.org/rhea/52512", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QCL8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QCL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLWAPLPLYCHSRPSTGGWQPLRFDGGAFHLKGTAELARALLVLRLCAWPPLVTHGLAFQAWSQRLLGSRLSRTLLRGSIYGQFVAGETAAEVKDCVQQLQALGLQHLLAVPTEEEPDSAAKTSEAWYEGNLSAMLRCVDLSRALVDTRGPARNSLMQLKMTALTSTQLCKELSAWIQRPAGSSELSPERLADAMDSGQNLRLSCLSADQNQHLQASLSRLHRVAQHARAQHVRLLVDAEYTFINPALSLLVAALALRWNRPEEGGPWVWNTYQAYLKETHKRLERDAEAAHKAGLAFGVKLVRGAYLDKERAMTQLQGKEDCTQPDYEATSRSYSRCLELMLRRVSRHGPLCHLMVASHNEESVLQATKRMWELGIPPDGPVCFGQLLGMCDHVSLALGQAGYVVYKSIPYGCLEEVIPYLIRRAQENRSVLQGARREQALLSQELWRRLLGRKV", "length": 456, "header": "tr|A0A8C2QCL8-1|A0A8C2QCL8_CRIGR Isoform 1 of Proline dehydrogenase OS=Cricetulus griseus OX=10029 GN=Prodh2 PE=3 SV=1 CANONICAL=A0A8C2QCL8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QCL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCL8/entry#A0A8C2QCL8-1", "sequence": { "sequence": "MLWAPLPLYCHSRPSTGGWQPLRFDGGAFHLKGTAELARALLVLRLCAWPPLVTHGLAFQAWSQRLLGSRLSRTLLRGSIYGQFVAGETAAEVKDCVQQLQALGLQHLLAVPTEEEPDSAAKTSEAWYEGNLSAMLRCVDLSRALVDTRGPARNSLMQLKMTALTSTQLCKELSAWIQRPAGSSELSPERLADAMDSGQNLRLSCLSADQNQHLQASLSRLHRVAQHARAQHVRLLVDAEYTFINPALSLLVAALALRWNRPEEGGPWVWNTYQAYLKETHKRLERDAEAAHKAGLAFGVKLVRGAYLDKERAMTQLQGKEDCTQPDYEATSRSYSRCLELMLRRVSRHGPLCHLMVASHNEESVLQATKRMWELGIPPDGPVCFGQLLGMCDHVSLALGQAGYVVYKSIPYGCLEEVIPYLIRRAQENRSVLQGARREQALLSQELWRRLLGRKV", "length": 456, "header": "tr|A0A8C2QCL8-1|A0A8C2QCL8_CRIGR Isoform 1 of Proline dehydrogenase OS=Cricetulus griseus OX=10029 GN=Prodh2 PE=3 SV=1 CANONICAL=A0A8C2QCL8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCL8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCL8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCL8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCL8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773901", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773901", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCL8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCL8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCL8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCL8" } ], "pmid": "" }, { "name": "proline dehydrogenase activity", "id": "GO:0004657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004657", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCL8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCL8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "L-proline catabolic process to L-glutamate", "id": "GO:0010133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010133", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCL8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23784", "name": "", "equation": "L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7FUS7-1", "A0A8C2QCL8-1" ], "evidence": [ { "id": "23784", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23784" } ] }, { "id": "52512", "name": "", "equation": "trans-4-hydroxy-L-proline + a quinone = (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + a quinol + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8C2QCL8-1" ], "evidence": [ { "id": "52512", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/52512" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8C2QCL8", "gene_name": "Prodh2", "activity": [ { "ec_number": "1.5.5.2", "activity": "L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+).", "evidence": [ { "id": "A0A8C2QCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCL8" } ] }, { "ec_number": "1.5.5.2", "activity": "", "evidence": [ { "id": "A0A8C2QCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCL8" } ] } ] }, { "uniprot_ac": "A0A9J7FUS7", "gene_name": "Prodh", "activity": [ { "ec_number": "1.5.5.2", "activity": "L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+).", "evidence": [ { "id": "A0A9J7FUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUS7" } ] }, { "ec_number": "1.5.5.2", "activity": "", "evidence": [ { "id": "A0A9J7FUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUS7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCL8" }, { "id": "PF01619", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01619" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Proline dehydrogenase", "eco_id": "ECO_0000259", "start_pos": 162, "end_pos": 434, "start_aa": "Thr", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.5.5.2", "ec_name": "L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+).", "evidence": [ { "id": "1.5.5.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.5.2" }, { "id": "1.5.5.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.5.5.2" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 429, "end_pos": 431 } ] }, "class_list": [], "section_stats": [ { 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QCP2-1", "uniprot_ac": "A0A8C2QCP2", "uniprot_id": "A0A8C2QCP2_CRIGR", "mass": { "chemical_mass": 17183.0, "monoisotopic_mass": 17183.0 }, "refseq": { "ac": "XP_027253437", "name": "dual specificity phosphatase 28 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253437" }, "gene_names": [ { "name": "Dusp28", "type": "recommended", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "name": "Dusp28", "type": "synonym", "evidence": [ { "id": "XP_027253437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253437" } ] } ], "protein_names": [ { "name": "Dual specificity phosphatase 28", "type": "recommended", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2/entry#names_and_taxonomy" } ] }, { "name": "dual specificity phosphatase 28 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027253437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253437" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027253437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253437" } ] }, { "annotation": "Has phosphatase activity with the synthetic substrate 6,8-difluoro-4-methylumbelliferyl phosphate (in vitro). Has almost no detectable activity with phosphotyrosine, even less activity with phosphothreonine and displays complete lack of activity with phosphoserine. The poor activity with phosphotyrosine may be due to steric hindrance by bulky amino acid sidechains that obstruct access to the active site.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2#function" }, { "database": "UniProtKB", "id": "ARBA00053960", "url": "https://www.uniprot.org/uniprotkb/ARBA00053960#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dusp28", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2", "locus": {} } ], "crossref": [ { "id": "113833604", "url": "https://www.ncbi.nlm.nih.gov/gene/113833604", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113833604", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113833604", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QCP2", "url": "https://www.orthodb.org/?gene=A0A8C2QCP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45961", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45961", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45961:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45961:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027253437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253437", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QCP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QCP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTPEAAPPPLARVAPALFIGNARAASATELLARAGITLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLLTHLEPTCAAMEAAVRGGGACLVYCKNGRSRSAAVCTAYLMRHGGHSLERAFQMVKSARPVAEPNLGFWAQLQKYEQTLQAQALLPGDPAEPE", "length": 163, "header": "tr|A0A8C2QCP2-1|A0A8C2QCP2_CRIGR Isoform 1 of Dual specificity phosphatase 28 OS=Cricetulus griseus OX=10029 GN=Dusp28 PE=3 SV=1 CANONICAL=A0A8C2QCP2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QCP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2/entry#A0A8C2QCP2-1", "sequence": { "sequence": "MGTPEAAPPPLARVAPALFIGNARAASATELLARAGITLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLLTHLEPTCAAMEAAVRGGGACLVYCKNGRSRSAAVCTAYLMRHGGHSLERAFQMVKSARPVAEPNLGFWAQLQKYEQTLQAQALLPGDPAEPE", "length": 163, "header": "tr|A0A8C2QCP2-1|A0A8C2QCP2_CRIGR Isoform 1 of Dual specificity phosphatase 28 OS=Cricetulus griseus OX=10029 GN=Dusp28 PE=3 SV=1 CANONICAL=A0A8C2QCP2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113833604", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113833604", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3H060-1", "G3H622-1", "G3H9Q0-1", "A0A8C2LH05-1", "G3HKY7-1", "G3GWQ6-1", "G3HBF6-1", "G3GRD1-1", "G3H8H2-1", "A0A9J7FG56-1", "A0A061IAM9-1", "A0A9J7GE78-1", "A0A9J7GZK0-1", "A0A061HX98-1", "A0A061HZS8-1", "A0A3L7HEJ5-1", "A0A8C2LYZ8-1", "A0A9J7JC04-1", "A0A8C2MQ28-1", "A0A3L7I231-1", "A0A9J7EY47-1", "A0A8C2LVB9-1", "A0A8C2MZ43-1", "A0A9J7G003-1", "A0A8C2QC02-1", "A0A9J7JD11-1", "A0A8C2QH88-1", "A0A9J7EXY7-1", "A0A9J7JC62-1", "A0A9J7FEN1-1", "A0A9J7FB56-1", "A0A9J7FEZ5-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FWX7-1", "A0A9J7G1A0-1", "A0A9J7JTT7-1", "A0A9J7G7L1-1", "A0A9J7G7K2-1", "A0A9J7GNR2-1", "A0A9J7JU39-1", "A0A9J7KAX8-1", "A0A9J7GQG9-1", "A0A9J7GX92-1", "A0A9J7F2A0-1", "A0A9J7EZC9-1", "A0A9J7EZL1-1", "A0A9J7FIV0-1", "A0A8C2MFV5-1", "A0A8C2N2E5-1", "A0A8C2N686-1", "A0A8C2QCP2-1", "A0A3L7IA07-1", "A0A9J7FYL8-1", "A0A9J7G168-1", "A0A9J7GBQ5-1", "A0A9J7H7L7-1", "A0A9J7HBK7-1", "A0A9J7GQC8-1", "A0A9J7H152-1", "A0A9J7KDA7-1", "A0A9J7KDM0-1", "A0A9J7J766-1", "A0A9J7FKB3-1", "A0A3L7HAL2-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GV48-1", "G3GWQ6-1", "G3H060-1", "G3H9Q0-1", "G3H7Z6-1", "G3I157-1", "G3HCQ6-1", "A0A8C2MA30-1", "G3HMJ7-1", "G3I434-1", "G3H622-1", "G3HKY7-1", "G3GRD1-1", "G3I4H5-1", "G3H8H2-1", "A0A9J7F890-1", "A0A8C2MW37-1", "A0A061I6V7-1", "A0A9J7GBP5-1", "A0A9J7JFN8-1", "A0A9J7G7W0-1", "A0A9J7GE78-1", "A0A061HVT3-1", "A0A061HX98-1", "A0A3L7HX32-1", "A0A8C2LYQ8-1", "A0A8C2M5N0-1", "A0A9J7JBH1-1", "A0A9J7EY47-1", "A0A8C2LGL9-1", "A0A8C2LVB9-1", "A0A8C2QH88-1", "A0A9J7F130-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FXD0-1", "A0A9J7G243-1", "A0A9J7GEM4-1", "A0A9J7G1B8-1", "A0A9J7K1J8-1", "A0A9J7K5S1-1", "A0A9J7EZL1-1", "A0A8C2QCP2-1", "A0A8C2LTP5-1", "A0A8C2N2E5-1", "A0A8C2QBZ1-1", "A0A3L7HBF4-1", "A0A9J7GK96-1", "A0A8C2LI03-1", "A0A9J7G0U7-1", "A0A9J7GD33-1", "A0A9J7H9S5-1", "A0A9J7HCJ8-1", "A0A9J7GJY7-1", "A0A9J7JYW1-1", "A0A3L7I513-1", "A0A9J7FKB3-1", "A0A8C2LGY1-1", "A0A3L7HEM4-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GV48-1", "G3GWQ6-1", "G3H060-1", "G3H9Q0-1", "G3H622-1", "G3HKY7-1", "G3H7Z6-1", "G3I157-1", "G3HCQ6-1", "A0A8C2MA30-1", "G3HMJ7-1", "A0A8C2MF90-1", "A0A9J7GX39-1", "G3I434-1", "G3GRD1-1", "G3I4H5-1", "G3H8H2-1", "A0A9J7F890-1", "A0A8C2MW37-1", "A0A061I6V7-1", "A0A9J7GBP5-1", "A0A9J7JFN8-1", "A0A9J7G7W0-1", "A0A9J7GE78-1", "A0A061HX98-1", "A0A3L7HEJ5-1", "A0A3L7HX32-1", "A0A8C2LYQ8-1", "A0A8C2M5N0-1", "A0A9J7JBH1-1", "A0A8C2ME51-1", "A0A8C2MTQ0-1", "A0A3L7IJ01-1", "A0A9J7EY47-1", "A0A8C2LGL9-1", "A0A8C2LVB9-1", "A0A8C2QH88-1", "A0A9J7F130-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FXD0-1", "A0A9J7G243-1", "A0A9J7GEM4-1", "A0A9J7G1B8-1", "A0A9J7K1J8-1", "A0A9J7K5S1-1", "A0A9J7EZL1-1", "A0A9J7F6Q7-1", "A0A8C2N2E5-1", "A0A8C2LTP5-1", "A0A8C2QBZ1-1", "A0A8C2QCP2-1", "A0A3L7HBF4-1", "A0A3L7HC66-1", "A0A9J7GK96-1", "A0A8C2LI03-1", "A0A9J7G0U7-1", "A0A9J7GD33-1", "A0A9J7H9S5-1", "A0A9J7HCJ8-1", "A0A9J7GJY7-1", "A0A9J7JXQ8-1", "A0A9J7JYW1-1", "A0A9J7FKB3-1", "A0A8C2LGY1-1", "A0A3L7HEM4-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HVT3", "gene_name": "Ppm1k", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.52", "activity": "O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + H2O = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.52", "activity": "", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] } ] }, { "uniprot_ac": "A0A061HX98", "gene_name": "Dusp9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] } ] }, { "uniprot_ac": "A0A061HZS8", "gene_name": "Ptpn14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HZS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZS8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HZS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZS8" } ] } ] }, { "uniprot_ac": "A0A061I6V7", "gene_name": "Pgam5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061I6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6V7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061I6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6V7" } ] } ] }, { "uniprot_ac": "A0A061IAM9", "gene_name": "LOC100766206", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] } ] }, { "uniprot_ac": "A0A3L7HAL2", "gene_name": "Pgp", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] } ] }, { "uniprot_ac": "A0A3L7HBF4", "gene_name": "Cpped1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBF4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBF4" } ] } ] }, { "uniprot_ac": "A0A3L7HC66", "gene_name": "Ppp6c", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HC66" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HC66" } ] } ] }, { "uniprot_ac": "A0A3L7HEJ5", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] } ] }, { "uniprot_ac": "A0A3L7HEM4", "gene_name": "Ctdspl2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEM4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEM4" } ] } ] }, { "uniprot_ac": "A0A3L7HX32", "gene_name": "Dusp8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] } ] }, { "uniprot_ac": "A0A3L7I231", "gene_name": "Ptp4a3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] } ] }, { "uniprot_ac": "A0A3L7I513", "gene_name": "Pdxp", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] } ] }, { "uniprot_ac": "A0A3L7IA07", "gene_name": "Ptp4a2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] } ] }, { "uniprot_ac": "A0A3L7IJ01", "gene_name": "Ppp2cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7IJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJ01" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7IJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJ01" } ] } ] }, { "uniprot_ac": "A0A8C2LGL9", "gene_name": "Ppp1cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LGL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGL9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LGL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGL9" } ] } ] }, { "uniprot_ac": "A0A8C2LGY1", "gene_name": "Ppp1ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LGY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGY1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LGY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGY1" } ] } ] }, { "uniprot_ac": "A0A8C2LH05", "gene_name": "Acp1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] } ] }, { "uniprot_ac": "A0A8C2LI03", "gene_name": "Ctdsp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI03" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI03" } ] } ] }, { "uniprot_ac": "A0A8C2LTP5", "gene_name": "LOC100752571", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LTP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTP5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LTP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTP5" } ] } ] }, { "uniprot_ac": "A0A8C2LVB9", "gene_name": "Dusp22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] } ] }, { "uniprot_ac": "A0A8C2LYQ8", "gene_name": "Ppm1l", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LYZ8", "gene_name": "Ptprf", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] } ] }, { "uniprot_ac": "A0A8C2M5N0", "gene_name": "Ppp1cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2M5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5N0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2M5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5N0" } ] } ] }, { "uniprot_ac": "A0A8C2MA30", "gene_name": "Phlpp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MA30" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MA30" } ] } ] }, { "uniprot_ac": "A0A8C2ME51", "gene_name": "Ppm1g", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2ME51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ME51" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2ME51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ME51" } ] } ] }, { "uniprot_ac": "A0A8C2MF90", "gene_name": "Ssh2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MF90" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MF90" } ] } ] }, { "uniprot_ac": "A0A8C2MFV5", "gene_name": "LOC100758361", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] } ] }, { "uniprot_ac": "A0A8C2MQ28", "gene_name": "Ptprz1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] } ] }, { "uniprot_ac": "A0A8C2MTQ0", "gene_name": "Ssh1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTQ0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTQ0" } ] } ] }, { "uniprot_ac": "A0A8C2MW37", "gene_name": "Ppp3cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ] } ] }, { "uniprot_ac": "A0A8C2MZ43", "gene_name": "Ptprg", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] } ] }, { "uniprot_ac": "A0A8C2N2E5", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] } ] }, { "uniprot_ac": "A0A8C2N686", "gene_name": "Ptp4a1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ] } ] }, { "uniprot_ac": "A0A8C2QBZ1", "gene_name": "Ctdspl", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QBZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QBZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ] } ] }, { "uniprot_ac": "A0A8C2QC02", "gene_name": "Ptpn6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] } ] }, { "uniprot_ac": "A0A8C2QCP2", "gene_name": "Dusp28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] } ] }, { "uniprot_ac": "A0A8C2QH88", "gene_name": "Dusp12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] } ] }, { "uniprot_ac": "A0A9J7EXY7", "gene_name": "Ptpn13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] } ] }, { "uniprot_ac": "A0A9J7EY47", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] } ] }, { "uniprot_ac": "A0A9J7EZC9", "gene_name": "Ptpn18", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] } ] }, { "uniprot_ac": "A0A9J7EZL1", "gene_name": "LOC113830718", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] } ] }, { "uniprot_ac": "A0A9J7F130", "gene_name": "LOC100769947", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F130" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F130" } ] } ] }, { "uniprot_ac": "A0A9J7F2A0", "gene_name": "Ptpn12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7F2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2A0" } ] } ] }, { "uniprot_ac": "A0A9J7F6Q7", "gene_name": "LOC103164195", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F6Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6Q7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F6Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6Q7" } ] } ] }, { "uniprot_ac": "A0A9J7F890", "gene_name": "Ctdsp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F890" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F890" } ] } ] }, { "uniprot_ac": "A0A9J7FB56", "gene_name": "Ptpru", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FB56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FB56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB56" } ] } ] }, { "uniprot_ac": "A0A9J7FEN1", "gene_name": "Eya1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] } ] }, { "uniprot_ac": "A0A9J7FEZ5", "gene_name": "Ptpn2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] } ] }, { "uniprot_ac": "A0A9J7FG56", "gene_name": "Cdc25c", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] } ] }, { "uniprot_ac": "A0A9J7FIV0", "gene_name": "LOC100763249", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] } ] }, { "uniprot_ac": "A0A9J7FKB3", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] } ] }, { "uniprot_ac": "A0A9J7FMB0", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] } ] }, { "uniprot_ac": "A0A9J7FWJ6", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FWX7", "gene_name": "LOC103158664", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] } ] }, { "uniprot_ac": "A0A9J7FXD0", "gene_name": "Ppm1f", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXD0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXD0" } ] } ] }, { "uniprot_ac": "A0A9J7FYL8", "gene_name": "Ptpn11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] } ] }, { "uniprot_ac": "A0A9J7G003", "gene_name": "Ptprs", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G003" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G003" } ] } ] }, { "uniprot_ac": "A0A9J7G0U7", "gene_name": "Pptc7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ] } ] }, { "uniprot_ac": "A0A9J7G168", "gene_name": "LOC100762307", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ] } ] }, { "uniprot_ac": "A0A9J7G1A0", "gene_name": "Ptpn4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] } ] }, { "uniprot_ac": "A0A9J7G1B8", "gene_name": "Phlpp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B8" } ] } ] }, { "uniprot_ac": "A0A9J7G243", "gene_name": "Ppm1a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G243" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G243" } ] } ] }, { "uniprot_ac": "A0A9J7G7K2", "gene_name": "Ptpn1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] } ] }, { "uniprot_ac": "A0A9J7G7L1", "gene_name": "Ptprj", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] } ] }, { "uniprot_ac": "A0A9J7G7W0", "gene_name": "Ptpmt1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.27", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] } ] }, { "uniprot_ac": "A0A9J7GBP5", "gene_name": "Rpap2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GBP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GBP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP5" } ] } ] }, { "uniprot_ac": "A0A9J7GBQ5", "gene_name": "LOC100764354", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ5" } ] } ] }, { "uniprot_ac": "A0A9J7GD33", "gene_name": "Ublcp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GD33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GD33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ] } ] }, { "uniprot_ac": "A0A9J7GE78", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] } ] }, { "uniprot_ac": "A0A9J7GEM4", "gene_name": "Ppm1e", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEM4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEM4" } ] } ] }, { "uniprot_ac": "A0A9J7GJY7", "gene_name": "Ppef1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJY7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJY7" } ] } ] }, { "uniprot_ac": "A0A9J7GK96", "gene_name": "Ppm1n", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK96" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK96" } ] } ] }, { "uniprot_ac": "A0A9J7GNR2", "gene_name": "Ptpn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNR2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNR2" } ] } ] }, { "uniprot_ac": "A0A9J7GQC8", "gene_name": "LOC100757114", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GQC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQC8" } ] } ] }, { "uniprot_ac": "A0A9J7GQG9", "gene_name": "Ptprd", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] } ] }, { "uniprot_ac": "A0A9J7GX39", "gene_name": "Ssh3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GX39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX39" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GX39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX39" } ] } ] }, { "uniprot_ac": "A0A9J7GX92", "gene_name": "Ptpre", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX92" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX92" } ] } ] }, { "uniprot_ac": "A0A9J7GZK0", "gene_name": "Ptprc", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZK0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZK0" } ] } ] }, { "uniprot_ac": "A0A9J7H152", "gene_name": "Ptprt", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H152" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7H152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H152" } ] } ] }, { "uniprot_ac": "A0A9J7H7L7", "gene_name": "Ptprh", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H7L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7L7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7H7L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7L7" } ] } ] }, { "uniprot_ac": "A0A9J7H9S5", "gene_name": "LOC100752571", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7H9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5" } ] } ] }, { "uniprot_ac": "A0A9J7HBK7", "gene_name": "Ptpn22", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7HBK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7HBK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ] } ] }, { "uniprot_ac": "A0A9J7HCJ8", "gene_name": "Ppp3cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7HCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7HCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" } ] } ] }, { "uniprot_ac": "A0A9J7J766", "gene_name": "Ptpn20", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7J766", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J766" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7J766", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J766" } ] } ] }, { "uniprot_ac": "A0A9J7JBH1", "gene_name": "Cdc14a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] } ] }, { "uniprot_ac": "A0A9J7JC04", "gene_name": "Eya3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JC04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC04" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JC04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC04" } ] } ] }, { "uniprot_ac": "A0A9J7JC62", "gene_name": "Tns2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC62" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC62" } ] } ] }, { "uniprot_ac": "A0A9J7JD11", "gene_name": "Ptprm", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JD11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD11" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JD11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD11" } ] } ] }, { "uniprot_ac": "A0A9J7JFN8", "gene_name": "Epm2a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] } ] }, { "uniprot_ac": "A0A9J7JTT7", "gene_name": "Ptpra", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JTT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTT7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JTT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTT7" } ] } ] }, { "uniprot_ac": "A0A9J7JU39", "gene_name": "Eya4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JU39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU39" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JU39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU39" } ] } ] }, { "uniprot_ac": "A0A9J7JXQ8", "gene_name": "Ppp2ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXQ8" } ] } ] }, { "uniprot_ac": "A0A9J7JYW1", "gene_name": "Ctdnep1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JYW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYW1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JYW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYW1" } ] } ] }, { "uniprot_ac": "A0A9J7K1J8", "gene_name": "LOC100761879", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7K1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1J8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7K1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1J8" } ] } ] }, { "uniprot_ac": "A0A9J7K5S1", "gene_name": "Ilkap", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7K5S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7K5S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S1" } ] } ] }, { "uniprot_ac": "A0A9J7KAX8", "gene_name": "Eya2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7KAX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAX8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7KAX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAX8" } ] } ] }, { "uniprot_ac": "A0A9J7KDA7", "gene_name": "Ptprb", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7KDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7KDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ] } ] }, { "uniprot_ac": "A0A9J7KDM0", "gene_name": "LOC100769324", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7KDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7KDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ] } ] }, { "uniprot_ac": "G3GRD1", "gene_name": "Dusp10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] } ] }, { "uniprot_ac": "G3GV48", "gene_name": "Ppm1b", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3GV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GV48" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3GV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GV48" } ] } ] }, { "uniprot_ac": "G3GWQ6", "gene_name": "Dusp29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] } ] }, { "uniprot_ac": "G3H060", "gene_name": "Dusp26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3H060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H060" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3H060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H060" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3H060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H060" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3H060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H060" } ] } ] }, { "uniprot_ac": "G3H622", "gene_name": "Dusp4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3H622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H622" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3H622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H622" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3H622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H622" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3H622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H622" } ] } ] }, { "uniprot_ac": "G3H7Z6", "gene_name": "Dusp23", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3H7Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H7Z6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3H7Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H7Z6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3H7Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H7Z6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3H7Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H7Z6" } ] } ] }, { "uniprot_ac": "G3H8H2", "gene_name": "Dusp19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3H8H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8H2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3H8H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8H2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3H8H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8H2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3H8H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8H2" } ] } ] }, { "uniprot_ac": "G3H9Q0", "gene_name": "Dusp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3H9Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H9Q0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3H9Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H9Q0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3H9Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H9Q0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3H9Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H9Q0" } ] } ] }, { "uniprot_ac": "G3HBF6", "gene_name": "Ptpn21", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3HBF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBF6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3HBF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBF6" } ] } ] }, { "uniprot_ac": "G3HCQ6", "gene_name": "Ctdp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3HCQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCQ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3HCQ6", "database": "UniProtKB", "url": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QCQ5-1", "uniprot_ac": "A0A8C2QCQ5", "uniprot_id": "A0A8C2QCQ5_CRIGR", "mass": { "chemical_mass": 34471.0, "monoisotopic_mass": 34471.0 }, "refseq": { "ac": "XP_003500773", "name": "rRNA methyltransferase 1, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500773" }, "gene_names": [ { "name": "Mrm1", "type": "recommended", "evidence": [ { "id": "A0A8C2QCQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCQ5" } ] }, { "name": "Mrm1", "type": "synonym", "evidence": [ { "id": "XP_003500773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500773" } ] } ], "protein_names": [ { "name": "rRNA methyltransferase 1, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8C2QCQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCQ5/entry#names_and_taxonomy" } ] }, { "name": "16S rRNA (guanosine(1145)-2'-O)-methyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8C2QCQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCQ5/entry#names_and_taxonomy" } ] }, { "name": "16S rRNA [Gm1145] 2'-O-methyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8C2QCQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCQ5/entry#names_and_taxonomy" } ] }, { "name": "rRNA methyltransferase 1, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_003500773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500773" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003500773.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003500773", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500773" } ] }, { "annotation": "S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1145 (Gm1145) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCQ5#function" }, { "database": "UniProtKB", "id": "ARBA00055894", "url": "https://www.uniprot.org/uniprotkb/ARBA00055894#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCQ5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mrm1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCQ5", "locus": {} } ], "crossref": [ { "id": "cd18105", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18105", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758744", "url": "https://www.ncbi.nlm.nih.gov/gene/100758744", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001537", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001537", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029026", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029026", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758744", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758744", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QVPPYEY", "url": "https://omabrowser.org/oma/group/QVPPYEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QCQ5", "url": "https://www.orthodb.org/?gene=A0A8C2QCQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46103:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46103:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08032", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08032", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003500773", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500773", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "47776", "url": "https://www.rhea-db.org/rhea/47776", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QCQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QCQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLLWTVGCFGILTARHFSPVARPGGEELSRLLLDDLPPTQRLERLFGLSPCLLALRAARRRVARLLLQAGKAGLQGERAELLRVAEARGIPVLRPRRQKLDALCGHQVHQGVCMEVSPLRPRLCDDEAAEASPGDDPQQLWLVLEGLQDPRNLGAVLRSAHFLGVDRVITSRRNSCPLTPVVSKASAGAVEVMDVFATSDLAGFLKAKAQQGWLVVGTVGCPGPEISHSTKVPITSCLEFIWDRPTLLVLGNEGSGLSQEVLASCQLLLTILPRRHLPPGLESLNVSVATGILLHSICSQKKSFPVQTEKGQLLQDT", "length": 318, "header": "tr|A0A8C2QCQ5-1|A0A8C2QCQ5_CRIGR Isoform 1 of rRNA methyltransferase 1, mitochondrial OS=Cricetulus griseus OX=10029 GN=Mrm1 PE=3 SV=1 CANONICAL=A0A8C2QCQ5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QCQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCQ5/entry#A0A8C2QCQ5-1", "sequence": { "sequence": "MRLLWTVGCFGILTARHFSPVARPGGEELSRLLLDDLPPTQRLERLFGLSPCLLALRAARRRVARLLLQAGKAGLQGERAELLRVAEARGIPVLRPRRQKLDALCGHQVHQGVCMEVSPLRPRLCDDEAAEASPGDDPQQLWLVLEGLQDPRNLGAVLRSAHFLGVDRVITSRRNSCPLTPVVSKASAGAVEVMDVFATSDLAGFLKAKAQQGWLVVGTVGCPGPEISHSTKVPITSCLEFIWDRPTLLVLGNEGSGLSQEVLASCQLLLTILPRRHLPPGLESLNVSVATGILLHSICSQKKSFPVQTEKGQLLQDT", "length": 318, "header": "tr|A0A8C2QCQ5-1|A0A8C2QCQ5_CRIGR Isoform 1 of rRNA methyltransferase 1, mitochondrial OS=Cricetulus griseus OX=10029 GN=Mrm1 PE=3 SV=1 CANONICAL=A0A8C2QCQ5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCQ5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCQ5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758744", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758744", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R9B5-1", "protein_name": "rRNA methyltransferase 1, mitochondrial", "gene_name": "MRM1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELLSAARGATWRCCGRLLTRPFSQAARRGDRPGGEELSRLLLDDLALPPRSAGGLELLFGLSPCLLALRAARRRVARLLLQAGRSGLQGERAELLRVAEARDIPVLRPRRRKLDVLCRYQVHQGVCMEVSPLRPQPWAEAGESRPGDDPQQLWLVLEGLQDPRNLGAVLRSAHFLGVEKVITSRKNSCPLTPVVSKASAGAMEVMDVFSTDDLAGFLQAKARQGWLVAGTVGCPGPEISPSSEVPITSCLDFLWDQPTLLVLGNEGSGLSREVQASCQLLLTILPGRQLPPGLESLNVSVAAGILLHSICSQRKGFPVEQKREQHLLQDPQEPWPLSEGPSLTQHPGLCSGSAKQRQDGD", "length": 361 }, "evidence": [ { "id": "A0A8C2QCQ5", "url": "https://omabrowser.org/oma/group/A0A8C2QCQ5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V1AB93-1", "protein_name": "rRNA methyltransferase 1, mitochondrial", "gene_name": "MRM1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MERALRSLARRALGLPSTARSRCFGEGPTRDQQPSRLCTAAARGGDGARTFRGGLHAAREGWGSAGREASKGRRRPEGRALPIERTRGSEILFGVAPCSMALSQARRDLFRLFLKRSGGPQRLVTSEFVLQAAARGVPVLHVGRRELDTLCGGRVHQGVCLEATPLRFKRLEEAEEPGLGDGESPNRQLLWLALEQIQDPMNLGALLRSAYFLGVDRVVTSQRNSCPLTPTVSKASSGAMEVFDVYSTDDLRSFLKAKAAEGWEVVGTVSQSETVENVPVISCLEFRWNKPIILVIGSEGDGLSLETQLLCHQMLVIPSGRALHPGIESLNVSVATGILLHSICSQKLRNSD", "length": 352 }, "evidence": [ { "id": "A0A8C2QCQ5", "url": "https://omabrowser.org/oma/group/A0A8C2QCQ5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZK81-1", "protein_name": "rRNA methyltransferase 1, mitochondrial", "gene_name": "Mrm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLLWTVGCFNRLVARHFSSVARPGERPGGEELSRLLLDDLAPAQRLERLFGVSPCLLALRAARRHVARLLLQAGKAGLQGERAELLRVAEARGIPVLRPRRQKLDALCGYQVHQGVCMEVSRLRPRPCDEAADTSSGDDPQQLWLVLEGIQDPRNLGAVMRSAYFLGVDRVITSRRNSCPLTPVVSKASAGAMEVMDVFASPDLASFLQAKAQQGWLVVGTVGCPGPEISQSSKVPVTSCLEFIWDRPTLLVLGNEGSGLSQGVFATCQLLLTILPGRHLPPGLESLNVSVATGILLHSICSQKKGFPVQERGQRLQDS", "length": 320 }, "evidence": [ { "id": "A0A8C2QCQ5", "url": "https://omabrowser.org/oma/group/A0A8C2QCQ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IN84-1", "protein_name": "rRNA methyltransferase 1, mitochondrial", "gene_name": "MRM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALLSTVRGATWGRLVTRHFSHAARHGERPGGEELSRLLLDDLVPTSRLELLFGMTPCLLALQAARRSVARLLLQAGKAGLQGKRAELLRMAEARDIPVLRPRRQKLDTMCRYQVHQGVCMEVSPLRPRPWREAGEASPGDDPQQLWLVLDGIQDPRNFGAVLRSAHFLGVDKVITSRRNSCPLTPVVSKSSAGAMEVMDVFSTDDLTGFLQTKAQQGWLVAGTVGCPSTEDPQSSEIPIMSCLEFLWERPTLLVLGNEGSGLSQEVQASCQLLLTILPRRQLPPGLESLNVSVAAGILLHSICSQRKGFPTEGERRQLLQDPQEPSARSEGLSMAQHPGLSSGPEKERQNEG", "length": 353 }, "evidence": [ { "id": "A0A8C2QCQ5", "url": "https://omabrowser.org/oma/group/A0A8C2QCQ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99J25-1", "protein_name": "rRNA methyltransferase 1, mitochondrial", "gene_name": "Mrm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRLWTVGCFSRLIARHFSSVARRGERPGGEELSRLLLDDLAPAQRLERLFGLSPCLLALRAARRRVARLLLQAGKAGLQGERAELLRVAEARGIPVLRPRRQKLDALCGYQVHQGVCMEVSPLRPRPCDEAADTSSGDDPQQLWLVLEGLQDPRNLGAVMRSAHFLGVDRVITSQRNSCPLTPVVSKASAGAMEVMDVFATPDLPGFLQAKAQQGWLVVGTVGCPGPEISQSSKVPITSCLEFVWDRPTLLVLGSEGSGLSQEVFASCQLLLTILPRRHLPPGLESLNVSVATGILLHSICSQKKGFPVQERGQLLQDS", "length": 320 }, "evidence": [ { "id": "A0A8C2QCQ5", "url": "https://omabrowser.org/oma/group/A0A8C2QCQ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCQ5" } ], "pmid": "" }, { "name": "rRNA (guanosine-2'-O-)-methyltransferase activity", "id": "GO:0070039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070039", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCQ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "47776", "name": "", "equation": "guanosine(1145) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(1145) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "47776", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47776" 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Splicing factor U2AF subunit OS=Cricetulus griseus OX=10029 GN=U2af2 PE=3 SV=1 CANONICAL=A0A8C2QCT9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LGF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCT9/entry#A0A8C2LGF1-1", "sequence": { "sequence": "MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW", "length": 456, "header": "tr|A0A8C2LGF1-1|A0A8C2LGF1_CRIGR Computationally mapped isoform of Splicing factor U2AF subunit OS=Cricetulus griseus OX=10029 GN=U2af2 PE=3 SV=1 CANONICAL=A0A8C2QCT9-1" }, "locus": {} }, { "isoform_ac": "A0A8C2QCT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCT9/entry#A0A8C2QCT9-1", "sequence": { "sequence": "MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSLPSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW", "length": 475, "header": "tr|A0A8C2QCT9-1|A0A8C2QCT9_CRIGR Isoform 1 of Splicing factor U2AF subunit OS=Cricetulus griseus OX=10029 GN=U2af2 PE=3 SV=1 CANONICAL=A0A8C2QCT9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GIC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCT9/entry#A0A9J7GIC8-1", "sequence": { "sequence": "MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW", "length": 471, "header": "tr|A0A9J7GIC8-1|A0A9J7GIC8_CRIGR Computationally mapped isoform of Splicing factor U2AF subunit OS=Cricetulus griseus OX=10029 GN=U2af2 PE=3 SV=1 CANONICAL=A0A8C2QCT9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JRQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCT9/entry#A0A9J7JRQ1-1", "sequence": { "sequence": "MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSLPSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW", "length": 460, "header": "tr|A0A9J7JRQ1-1|A0A8C2QCT9_CRIGR Computationally mapped isoform of Splicing factor U2AF subunit OS=Cricetulus griseus OX=10029 GN=U2af2 PE=3 SV=1 CANONICAL=A0A8C2QCT9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 133, "start_aa": "Thr", "end_pos": 133, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr133", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 135, "start_aa": "Thr", "end_pos": 135, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr135", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JRQ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRQ1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JRQ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRQ1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769215", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769215", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCT9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCT9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCT9" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QCT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCT9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QCT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCT9" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 149, "end_pos": 231, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 133, 135 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 311, "end_pos": 313 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 352, "end_pos": 354 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QCV8-1", "uniprot_ac": "A0A8C2QCV8", "uniprot_id": "A0A8C2QCV8_CRIGR", "mass": { "chemical_mass": 35228.0, "monoisotopic_mass": 35228.0 }, "refseq": { "ac": "XP_007643911", "name": "olfactory receptor 5W2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643911" }, "gene_names": [ { "name": "LOC100752029", "type": "recommended", "evidence": [ { "id": "A0A8C2QCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCV8" } ] }, { "name": "LOC100752029", "type": "synonym", "evidence": [ { "id": "XP_007643911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643911" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A8C2QCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCV8/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5W2", "type": "synonym", "evidence": [ { "id": "XP_007643911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643911" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614125.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027256353", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256353" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QD59", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QD59" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Asxl3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QD59", "locus": {} } ], "crossref": [ { "id": "100759073", "url": "https://www.ncbi.nlm.nih.gov/gene/100759073", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024811", "database": "InterPro", "categories": [ "Protein Classification" ] 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"length": 2204, "header": "tr|A0A8C2QD59-1|A0A8C2QD59_CRIGR Isoform 1 of Polycomb group protein ASXL3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Asxl3 PE=3 SV=1 CANONICAL=A0A8C2QD59-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1290, "start_aa": "Thr", "end_pos": 1290, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1290", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2141, "start_aa": "Thr", "end_pos": 2141, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2141", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"Defb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTHYFLLVMLFFLFSQMELGAGILTSLGRRTDQYRCLQNGGFCLRSSCPSHTKLQGTCKPDKPNCCRS", "length": 69 }, "evidence": [ { "id": "A0A8C2QDC2", "url": "https://omabrowser.org/oma/group/A0A8C2QDC2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56386-1", "protein_name": "Beta-defensin 1", "gene_name": "Defb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTHYFLLVMICFLFSQMEPGVGILTSLGRRTDQYKCLQHGGFCLRSSCPSNTKLQGTCKPDKPNCCKS", "length": 69 }, "evidence": [ { "id": "A0A8C2QDC2", "url": "https://omabrowser.org/oma/group/A0A8C2QDC2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P60022-1", "protein_name": "Beta-defensin 1", "gene_name": "DEFB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK", "length": 68 }, "evidence": [ { "id": "A0A8C2QDC2", "url": "https://omabrowser.org/oma/group/A0A8C2QDC2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDC2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "defense response to Gram-negative bacterium", "id": "GO:0050829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDC2" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDC2" } ], "pmid": "" }, { "name": "innate immune response in mucosa", "id": "GO:0002227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002227", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDC2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "CCR6 chemokine receptor binding", "id": "GO:0031731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031731", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QDC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDC2" }, { "id": "PF00711", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00711" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-defensin-like", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 67, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QDF7-1", "uniprot_ac": "A0A8C2QDF7", "uniprot_id": "A0A8C2QDF7_CRIGR", "mass": { "chemical_mass": 60369.0, "monoisotopic_mass": 60369.0 }, "refseq": { "ac": "XP_003496165", "name": "protein RFT1 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496165" }, "gene_names": [ { "name": "Rft1", "type": "recommended", "evidence": [ { "id": "A0A8C2QDF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDF7" } ] }, { "name": "Rft1", "type": "synonym", "evidence": [ { "id": "XP_003496165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496165" } ] } ], "protein_names": [ { "name": "Protein RFT1 homolog", "type": "recommended", "evidence": [ { "id": "A0A8C2QDF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDF7/entry#names_and_taxonomy" } ] }, { "name": "protein RFT1 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003496165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496165" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613611.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003496165", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496165" } ] }, { "annotation": "Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues. However, the intramembrane lipid transporter activity could not be confirmed in vitro.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDF7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDF7#function" }, { "database": "UniProtKB", "id": "ARBA00045912", "url": "https://www.uniprot.org/uniprotkb/ARBA00045912#function" }, { "database": "UniProtKB", "id": "RU365067", "url": "https://www.uniprot.org/uniprotkb/RU365067#function" }, { "database": "UniProtKB", "id": "A0A9J7H9S0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDF7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDF7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rft1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDF7", "locus": {} } ], "crossref": [ { "id": "100774638", "url": "https://www.ncbi.nlm.nih.gov/gene/100774638", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774638", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774638", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WPGKLFG", "url": "https://omabrowser.org/oma/group/WPGKLFG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QDF7", "url": "https://www.orthodb.org/?gene=A0A8C2QDF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13117:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13117:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04506", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04506", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003496165", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496165", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QDF7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QDF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9S0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSQEALGQAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGIVNVRLTLLYSTTIFLAREAFRKACLSGGAQRDWSQTLNLLWLTVPLGVFWSLLLGWVWLQLLEVPDPDVVPYYGAGVVLFGLSAVVELLGEPFWVLAQAHMFVKLKVLAESVSVILRSILTAFLVLWLPHWGLYIFSLAQLFYTTVLVLCYVIYLIKLLRSPESAKQLTLPVSRITQLLPSITRSRAFVNWKEAKLTWSFFKQSFLKQILTEGERYVMTFFNVLNFGDQGVYDIVNNLGSLVARLIFQPIEESFYIFFAKVLEREKDATHQKQEDIAVAAAVLESLLKLALLTGLTITVFGFAYSQLALDIYGGAMLSSGSGPVLMCSYCFYVLLLAINGVTECFTFAAMSKEEVDRYNFTMLALSSSFLVLSYLLTSWCGSVGFILANCFNMCIRITQSLSFIHHYFQRSPHKPLAGLNLSPFLLGVFALSGGITSVSETLLCCEQGWPARLAHIAVGTICLGVTLGTAFFTETKLINFLRTQLGRSRLSDKMT", "length": 541, "header": "tr|A0A8C2QDF7-1|A0A8C2QDF7_CRIGR Isoform 1 of Protein RFT1 homolog OS=Cricetulus griseus OX=10029 GN=Rft1 PE=3 SV=1 CANONICAL=A0A8C2QDF7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QDF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDF7/entry#A0A8C2QDF7-1", "sequence": { "sequence": "MGSQEALGQAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGIVNVRLTLLYSTTIFLAREAFRKACLSGGAQRDWSQTLNLLWLTVPLGVFWSLLLGWVWLQLLEVPDPDVVPYYGAGVVLFGLSAVVELLGEPFWVLAQAHMFVKLKVLAESVSVILRSILTAFLVLWLPHWGLYIFSLAQLFYTTVLVLCYVIYLIKLLRSPESAKQLTLPVSRITQLLPSITRSRAFVNWKEAKLTWSFFKQSFLKQILTEGERYVMTFFNVLNFGDQGVYDIVNNLGSLVARLIFQPIEESFYIFFAKVLEREKDATHQKQEDIAVAAAVLESLLKLALLTGLTITVFGFAYSQLALDIYGGAMLSSGSGPVLMCSYCFYVLLLAINGVTECFTFAAMSKEEVDRYNFTMLALSSSFLVLSYLLTSWCGSVGFILANCFNMCIRITQSLSFIHHYFQRSPHKPLAGLNLSPFLLGVFALSGGITSVSETLLCCEQGWPARLAHIAVGTICLGVTLGTAFFTETKLINFLRTQLGRSRLSDKMT", "length": 541, "header": "tr|A0A8C2QDF7-1|A0A8C2QDF7_CRIGR Isoform 1 of Protein RFT1 homolog OS=Cricetulus griseus OX=10029 GN=Rft1 PE=3 SV=1 CANONICAL=A0A8C2QDF7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDF7/entry#A0A9J7H9S0-1", "sequence": { "sequence": "MGSQEALGQAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGIVNVRLTLLYSTTIFLAREAFRKACLSGGAQRDWSQTLNLLWLTVPLGVFWSLLLGWVWLQLLEVPDPDVVPYYGAGVVLFGLSAVVELLGEPFWVLAQAHMFVKLKVLAESVSVILRSILTAFLVLWLPHWGLYIFSLAQLFYTTVLVLCYVIYLIKLLRSPESAKQLTLPVSRITQLLPSITRSRAFVNWKEAKLTWSFFKQSFLKQILTEGVYDIVNNLGSLVARLIFQPIEESFYIFFAKVLEREKDATHQKQEDIAVAAAVLESLLKLALLTGLTITVFGFAYSQLALDIYGGAMLSSGSGPVLMCSYCFYVLLLAINGVTECFTFAAMSKEEVDRYNFTMLALSSSFLVLSYLLTSWCGSVGFILANCFNMCIRITQSLSFIHHYFQRSPHKPLAGLNLSPFLLGVFALSGGITSVSETLLCCEQGWPARLAHIAVGTICLGVTLGTAFFTETKLINFLRTQLGRSRLSDKMT", "length": 524, "header": "tr|A0A9J7H9S0-1|A0A9J7H9S0_CRIGR Computationally mapped isoform of Protein RFT1 homolog OS=Cricetulus griseus OX=10029 GN=Rft1 PE=3 SV=1 CANONICAL=A0A8C2QDF7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDF7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDF7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDF7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDF7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774638", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774638", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AQX7-1", "protein_name": "Protein RFT1 homolog", "gene_name": "RFT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSREVLGQAARLASSGLLLQVLFRVITFVLNAFILRFLSKEIVGVVNVRLTLLYSTTIFLAREAFRRACLSGGTQRHWSQTLNLLWLTVPLGVFWSLFLGWVWLQLLEVPDPNVVPHYGTGVAAFGLSAVVELLGEPLWVLAQAHMFVRLKVIAESLSVILKSILTALLVLWLPHWGLYIFSLAQLFFTAVLVLCYVIYFTKLLGSPESSKGQVLPVSRMTDLLPSITRSRAFVNWEEAKLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLIFQPIEESFYIFFAKVLEREKDATLQKQEDVAVAAAVLESLLKLALLTGLTITVFGFAYSQLALDIYGGAMLSSGSGPVLLRAYCLYVLLLAINGVTECFTFAAMSKEEVDRYNFTMLALSSSFLGLSYLLTHWCGSVGFILANCFNMGIRITQSLRFIHRYYQKSPHRPLASLYLSPVLLGAFALSGGITAVSEVFLCCERGWPARLAHITVGALCLGATLRTVFLTETKLIHFLRTQLAVSRLADKTT", "length": 541 }, "evidence": [ { "id": "A0A8C2QDF7", "url": "https://omabrowser.org/oma/group/A0A8C2QDF7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V1AJA2-1", "protein_name": "Protein RFT1 homolog", "gene_name": "RFT1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAARAALRQTARLASSSALLQVLFRAVTFGLNALTLRYLSRELLGVVSVRLTLLYSTAVFLAREAFRRACLSGGAERSWAATINLLWLTVPLGVFWSAFLGFVWLHLLEVPDPSVVPHYRAGVVAFGLSAVVELLGEPCWVLAQAHLFVRLKVIAESLSIVSKCILTVVLVVLYPQWGLYIFSLAQLFYTSVLVTCYVVYFAKFLGSPEATKKSFPITRMKALLPNLMADKTFLNWKEARLTWSFFKQSFLKQILTEGERYVMTFLNVINFGDQGVYDAVNNLGSLVARFIFLPIEESFYVFFAQVLERGKNVKDQKQDDVAMAANVLELLLKLVLLIGLTIAVFGYAFSQLALDIYGGSMLSSGTGPDLLRCYSLYVLFLAVNGVTECFTFASMCKEEVDRYNFVMLALSFTFLCISYFLTRWHGSVGFILANCFNMGIRIAHSIHYIYGYFKESSYRPLTGLLPSPFLVLAYIISGGITVYSEAFFCCDKGWTARLIHISIGALCFAATTVTMLCTETKLVRFVRSQFLSQYMKKGT", "length": 539 }, "evidence": [ { "id": "A0A8C2QDF7", "url": "https://omabrowser.org/oma/group/A0A8C2QDF7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A6W4-1", "protein_name": "Protein RFT1 homolog", "gene_name": "Rft1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSQEVLGQAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGVVNVRLTLLYSTTIFLAREAFRRACLSGGTQRDWTQTLNLLWLTVPLGIFWSLCLGWVWLQLLEVPDPNVVPYYGTGVLLFGLSAVVELLGEPFWVLAQAHMFVKLKVLAESMSVILRSVLTALLVLWLPHWGLYIFSLAQLLYTAVLVLCYMLYLIKLLRSPESSKQLTLPISKVTQLLPSISRRKAFVNWNEARLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGIYDIVNNLGSLVARLIFQPVEESFYIFFAKVLEREKDASLQKQDDVAVAAAVLESLLKLALLTGLTVTVFGFAYSQLALDIYGGAMLSSGSGPVLMRCYCLYVLLLAVNGVTECFTFAAMSKEDVDRYNFTMLALSSSFLVLSYLLTSWCGSVGFIMANCFNMGIRITQSLSFIHHYFQESPHRPLAGLLLSPVLLGVFVLSAGITSVSEAFLCCERGWPARLAHIAVGTICLGVTLGTAFLTETKLIHFLRTQLGRSRLGDKMT", "length": 541 }, "evidence": [ { "id": "A0A8C2QDF7", "url": "https://omabrowser.org/oma/group/A0A8C2QDF7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BNC6-1", "protein_name": "Protein RFT1 homolog", "gene_name": "RFT1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSREVLGQAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGIVNVRLTLLYSTTIFLAREAFRRACLSGAAQRDWSQTLNLLWLTVPLGVFWSLFLGWVWLQLLEVPDPHVVPHYGTGVVVFGFSAVVELLGEPFWVLAQAHMFVKLKVIAESLSVILKSVLTALLVLWLPHWGLYIFSLAQLFYTTLLVLCYVIYFAKVLGSPESAKQQALPVSRMTDLLPSMTRSRAFVNWEEAKLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLLFQPIEESFYIFFAKVLEREKDATLQKQEDVAVAAVVLESLLKLALLTGLTITVFGFAYSQLVLDIYGGAMLSSGSGPVLLRAYCLYVLLLAINGVTECFTFAAMSKAEVDRYNFTMLALSSSFLMLSYVLTRWCGSVGFILANCFNMGIRIMQSLYFIYRYYRKSPHRPLDGLFLSPVLLGTFALSGGITAVSEVFLCCERGWLARLAHIAVGALCLGVTLGTAFLTETKLIHFLRTQLGVPRLADKMT", "length": 541 }, "evidence": [ { "id": "A0A8C2QDF7", "url": "https://omabrowser.org/oma/group/A0A8C2QDF7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7EXE6-1", "protein_name": "Protein RFT1 homolog", "gene_name": "rft1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSEDVLKSASTLASYNVLLQVMFRVLTFLLNAFTLRFVSKELIGVVNVRLMLLYSTLVFLSREAFRRACLSGEGAGRNWRQVINLLWLTFPLGCVWGVLLVCVWWWVLQAPDPDSIPHYVPAVGLFCVAALTELLAEPLWVLAHAHMFVRLKVIAESLAMIAKCLVTVVLVVSAPQWGLFIFSAAQCVYTGFLLTCYVVYFIHFLGSEEAEKKSFPVYRMTDLLPSKVDHEPLLNWKLTTLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIINNLGSMVARFLFLPIEESFYVFFAKVLERGRDVQHQKQEEVSMAAEVLECLLKLVLLIGLIITVFGYAYSHLALDIYGGELLSNGAGPALLRCYSCYVLLLAINGVTECFVFAAMSKEEVDRYNLVMLGLSASFLLLSYWLTWMFGGVGFILANCCNMALRITHSIVYIRQYFLQSEHRPLWGLRPHSAVLVALGVSAVITAFSESVFCCDGGWLLRLFHVAVGAVCLLTVVITVFLTETRLVQFVKTQLLPKYNKKLT", "length": 540 }, "evidence": [ { "id": "A0A8C2QDF7", "url": "https://omabrowser.org/oma/group/A0A8C2QDF7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P38206-1", "protein_name": "Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1", "gene_name": "RFT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAKKNSQLPSTSEQILERSTTGATFLMMGQLFTKLVTFILNNLLIRFLSPRIFGITAFLEFIQGTVLFFSRDAIRLSTLRISDSGNGIIDDDDEEEYQETHYKSKVLQTAVNFAYIPFWIGFPLSIGLIAWQYRNINAYFITLPFFRWSIFLIWLSIIVELLSEPFFIVNQFMLNYAARSRFESIAVTTGCIVNFIVVYAVQQSRYPMGVVTSDIDKEGIAILAFALGKLAHSITLLACYYWDYLKNFKPKKLFSTRLTKIKTRENNELKKGYPKSTSYFFQNDILQHFKKVYFQLCFKHLLTEGDKLIINSLCTVEEQGIYALLSNYGSLLTRLLFAPIEESLRLFLARLLSSHNPKNLKLSIEVLVNLTRFYIYLSLMIIVFGPANSSFLLQFLIGSKWSTTSVLDTIRVYCFYIPFLSLNGIFEAFFQSVATGDQILKHSYFMMAFSGIFLLNSWLLIEKLKLSIEGLILSNIINMVLRILYCGVFLNKFHRELFTDSSFFFNFKDFKTVIIAGSTICLLDWWFIGYVKNLQQFVVNVLFAMGLLALILVKERQTIQSFINKRAVSNSKDV", "length": 574 }, "evidence": [ { "id": "A0A8C2QDF7", "url": "https://omabrowser.org/oma/group/A0A8C2QDF7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54IV7-1", "protein_name": "Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1", "gene_name": "rft1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQPQTESNVLKNGLVGAFYLIGLQIISRLFTFIINTLVIVGVDDSIFGVSAIQYQLLSSIILFLSREAIRRACTRVNITDKLNNDNNLKSVINLSWLVLPIGIGLSIIFENFFLYTSTKETLEILNYHYGLRLFTISSILELLSEPMYILAQNLLLFKIRTTVEGFALFFKTFSTYYFIVILNMGLIGFGYAQILYSLTLVIGYFGYFLINIINNNKNKDNKEFSNCFKSIDQLFPKFSTRIDRNLIKLSLLYTWQSIYKLLLQEGEKFVLFFSETNQGQAIFAIVSNLGSLIVRFLFLPIEETCFLMFPKLFPTINNNNNNNNNNNNNNNNNNKNQENNNNNDDFKNGANVLIVIMKFLILVSLVFTCFGPGFSHLLLNLLYNNKFRDTNAGVLLGFYCIYVGFLAINGVSESFVHSVAKEDQLKTVNWVLIIIGFIYLLFTLIFCKLFQNIGIILANCLNIKLSNMIPNKMVLLSFIISFIITNLSNKYIYNAVSFKSTCIHLLIGIICFIQTCTFIYLKEWVSIKEFKKILSNKNK", "length": 540 }, "evidence": [ { "id": "A0A8C2QDF7", "url": "https://omabrowser.org/oma/group/A0A8C2QDF7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8C3B8-1", "protein_name": "Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1", "gene_name": "Rft1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQEVLGQAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGIVNVRLTLLYSTTTFLAREAFRRACLSGGAQRDWSQTLNLLWLTVPLGIFWSSCLGWVWLQLLEVPDPDVVPYYGTGVLFFGLSAVVELLGEPFWVLAQAHMFVKLKVLAESMSVILRSVLTALLVLWLPHWGLYIFSLAQLLYTTVLVLCYAIYLIQLLRSPESAKQLTLPVSRVTQLLPSISRSRAFVNWKEAGLAWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLIFQPVEESFYLFFAKVLEREKDASLQKQDDVAVAAAVLESLLKLALLTGLTMTVFGFAYSQLALDIYGGAMLSSGSGPVLMRCYCLYVLLLAINGVTECFMFAAMSKEEVDRYNFTMLALSSSFLVLSYLLTSWCGSVGFIMANCFNMGIRITQSLSFIHHYFRESPHRPLAGLRLSPVLLGVFILSAGITSVSEAFLCCERGWPARLAHIAVGTICLGVTLGTAFLTETKLIHFLRTQLGRSRLSDKMT", "length": 541 }, "evidence": [ { "id": "A0A8C2QDF7", "url": "https://omabrowser.org/oma/group/A0A8C2QDF7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96AA3-1", "protein_name": "Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1", "gene_name": "RFT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSQEVLGHAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGVVNVRLTLLYSTTLFLAREAFRRACLSGGTQRDWSQTLNLLWLTVPLGVFWSLFLGWIWLQLLEVPDPNVVPHYATGVVLFGLSAVVELLGEPFWVLAQAHMFVKLKVIAESLSVILKSVLTAFLVLWLPHWGLYIFSLAQLFYTTVLVLCYVIYFTKLLGSPESTKLQTLPVSRITDLLPNITRNGAFINWKEAKLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLIFQPIEESFYIFFAKVLERGKDATLQKQEDVAVAAAVLESLLKLALLAGLTITVFGFAYSQLALDIYGGTMLSSGSGPVLLRSYCLYVLLLAINGVTECFTFAAMSKEEVDRYNFVMLALSSSFLVLSYLLTRWCGSVGFILANCFNMGIRITQSLCFIHRYYRRSPHRPLAGLHLSPVLLGTFALSGGVTAVSEVFLCCEQGWPARLAHIAVGAFCLGATLGTAFLTETKLIHFLRTQLGVPRRTDKMT", "length": 541 }, "evidence": [ { "id": "A0A8C2QDF7", "url": "https://omabrowser.org/oma/group/A0A8C2QDF7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Y123-1", "protein_name": "Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MARNVLESSLLGAGFSIIFQILCRILTFGINAYIVRHVGREVLGIMNVRLLLLESTLLFLSREAINRAALSANAQQGDRCSWAQLINQMWLTVPICAVLCAPCLYIWLNWLSAVDAIYASQYEFACYAVAFSCVLELMAESAVFVAQVFCFVKLKILLNTLHILVRSAIFLWIVTGDRSAAINAFAIAQLSSAVTIVLGQYGFFYFYLKGFKDFVTQQAKKKPVAPKAWQVSLYEHMDDFPFKQLSDFLPGVMFNPNGKHFNRELQTLTLSFVKQGVLKQILTEGEKYVMSVSPVLSFGEQATYDVVNNLGSMAARFIFRPIEDSSYFYFTQTLSRDIKLAKQPQERVRQASSVLNNLLLGVSSIGLIAFTFGQSYSYPVLLLYGGPDFVAGGLPQSLLQWHCLAIYLLAVNGISEGYMFATNTSRDIDKYNYLMAIFSVSFLVLSYILTGIFGPVGFIFANCINMLSRILYSTYYIRHQYRPLSLDPLLGLWPGKLFGCTLFLAGIVCYWYQSSDLATHLGVGVLAGLACLLSWALAHRDLVRLAWRYGRRIKIE", "length": 556 }, "evidence": [ { "id": "A0A8C2QDF7", "url": "https://omabrowser.org/oma/group/A0A8C2QDF7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDF7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDF7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "dolichol-linked oligosaccharide biosynthetic process", "id": "GO:0006488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006488", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDF7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDF7" } ], "pmid": "" }, { "name": "glycolipid translocation", "id": "GO:0034203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034203", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDF7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDF7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glycolipid floppase activity", "id": "GO:0034202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034202", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDF7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDF7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 405, "end_pos": 407 }, { "start_pos": 466, "end_pos": 468 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QDH0-1", "uniprot_ac": "A0A8C2QDH0", "uniprot_id": "A0A8C2QDH0_CRIGR", "mass": { "chemical_mass": 65813.0, "monoisotopic_mass": 65813.0 }, "refseq": { "ac": "XP_027260657", "name": "TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260657" }, "gene_names": [ { "name": "Taf5l", "type": "recommended", "evidence": [ { "id": "A0A8C2QDH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDH0" } ] }, { "name": "Taf5l", "type": "synonym", "evidence": [ { "id": "XP_027260657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260657" } ] } ], "protein_names": [ { "name": "TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L", "type": "recommended", "evidence": [ { "id": "A0A8C2QDH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDH0/entry#names_and_taxonomy" } ] }, { "name": "PCAF-associated factor 65 beta", "type": "synonym", "evidence": [ { "id": "A0A8C2QDH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDH0/entry#names_and_taxonomy" } ] }, { "name": "TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L", "type": "synonym", "evidence": [ { "id": "XP_027260657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260657" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260657", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260657" } ] }, { "annotation": "Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. With TAF6L, acts as an epigenetic regulator essential for somatic reprogramming. Regulates target genes through H3K9ac deposition and MYC recruitment which trigger MYC regulatory network to orchestrate gene expression programs to control embryonic stem cell state.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDH0#function" }, { "database": "UniProtKB", "id": "ARBA00056767", "url": "https://www.uniprot.org/uniprotkb/ARBA00056767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDH0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Taf5l", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDH0", "locus": {} } ], "crossref": [ { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08044", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08044", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768389", "url": "https://www.ncbi.nlm.nih.gov/gene/100768389", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ 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"MKRVRTEQVQVAVSCYLKRRQYVDSDGPLKQGLRLSQTPEEMAANLTVQSESGCANAVSAAPCQAEPQQYEVQFGRLRSFLTDSDSQHSHEVMPLLYPLFVYLHLNLVQSGPKSTVESFYSRFHGMFLQNASQKDIIEQLQTTQTIQDILSNFQLRAFLDNKYVVRLQEDSYNYLIRYLQSDNNTALCKVLAVHIHLDVQPAKRTDYQLYASGSSSRSESSGLEPPDVPNPILQNEAALEVLQESIKRVKDGPPSLTTICFYAFYNTEQLLNTAEISSDSKLLAAGFDNSCIKLWSLRSKKLKSEPHHVDTSRIRLACDTLEEEESEEDNTGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDVDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLSFSPNGKYLASAGEDQRLKLWDLASGTLFKELRGHTDSITSLAFSPDSGLVASASMDNSVRVWDIRSTCCNTPADGSSGELVGVYTGQMSNVLSVQFMACNLLLVTGITQENQEH", "length": 589, "header": "tr|A0A8C2QDH0-1|A0A8C2QDH0_CRIGR Isoform 1 of TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L OS=Cricetulus griseus OX=10029 GN=Taf5l PE=3 SV=1 CANONICAL=A0A8C2QDH0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QDH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDH0/entry#A0A8C2QDH0-1", "sequence": { "sequence": 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based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265640", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265640", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LJX1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LJX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QDI1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QDI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVRPGLWPAILGIVLAAWLRGSGAQQSATVASPVPGASPDLLPHFLVEPEDVYIVKNKPVLLVCKAVPATQIFFKCNGEWVRQVDHVTERSTDGSSGLPTMEVRINVSRQQVEKVFGLEEYWCQCVAWSSSGTTKSQKAYIRIAYLRKNFEQEPLAKEVSLEQGIVLPCRPPEGIPPAEVEWLRNEDLVDPSLDPNVYITREHSLVVRQARLADTANYTCVAKNIVARRRSASAAVIVYVNGGWSTWTEWSVCSASCGRGWQKRSRSCTNPAPLNGGAFCEGQNVQKTACATLCPVDGSWGSWSKWSACGLDCTHWRSRECSDPAPRNGGEECRGADLDTRNCTSDLCLHTASGPEDVALYIGLVAVAVCLILLLLVLILIYCRKKEGLDSDVADSSILTSGFQPVSIKPNKADNPHLLTIQPDLSTTTTTYQGSLCPRQDGPSPKFQLSNGHLLSPLGGGRHTLHHSSPTSEAEDFVSRLSTQNYFRTLPRGTSNMAYGTFNFLGGRLMIPNTGISLLIPPDAIPRGKIYEIYLTLHKPEDVRLPLAGCQTLLSPIVSCGPPGVLLTRPVILAMDHCGEPSPDSWSLHLKKQSCEGSWEDVLHLGEESPSHLYYCQLEAGACYVFTEQLGRFALVGEALSVAATKRLKLLLFAPVACTSLEYNIRVYCLHDTHDALKEVLQLEKQLGGQLIQEPRVLHFKDSYHSLRLSIHDVPSSLWKSKVLVSYQEIPFYHIWNGTQQHLHCTFTLERVNPSTSDLACKVWVWQVEGDGQSFNINFNITKDTRFAELLALESEGGVPALVGPSAFKIPFLIRQKIITSLDPPCSRGADWRTLAQKLHLDSHLSFFASKPSPTAMLLNLWEARHFPNGNLGQLAAAVAGLGQPDAGLFTVSEAEC", "length": 898, "header": "tr|A0A8C2QDI1-1|A0A8C2QDI1_CRIGR Isoform 1 of Netrin receptor UNC5 OS=Cricetulus griseus OX=10029 GN=Unc5a PE=3 SV=1 CANONICAL=A0A8C2QDI1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LJX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDI1/entry#A0A8C2LJX1-1", "sequence": { "sequence": "MAVRPGLWPAILGIVLAAWLRGSGAQQSATVASPVPGASPDLLPHFLVEPEDVYIVKNKPVLLVCKAVPATQIFFKCNGEWVRQVDHVTERSTDGSSGLPTMEVRINVSRQQVEKVFGLEEYWCQCVAWSSSGTTKSQKAYIRIAYLRKNFEQEPLAKEVSLEQGIVLPCRPPEGIPPAEVEWLRNEDLVDPSLDPNVYITREHSLVVRQARLADTANYTCVAKNIVARRRSASAAVIVYVDGSWGSWSKWSACGLDCTHWRSRECSDPAPRNGGEECRGADLDTRNCTSDLCLHTASGPEDVALYIGLVAVAVCLILLLLVLILIYCRKKEGLDSDVADSSILTSGFQPVSIKPNKADNPHLLTIQPDLSTTTTTYQGSLCPRQDGPSPKFQLSNGHLLSPLGGGRHTLHHSSPTSEAEDFVSRLSTQNYFRTLPRGTSNMAYGTFNFLGGRLMIPNTGISLLIPPDAIPRGKIYEIYLTLHKPEDVRLPLAGCQTLLSPIVSCGPPGVLLTRPVILAMDHCGEPSPDSWSLHLKKQSCEGSWEDVLHLGEESPSHLYYCQLEAGACYVFTEQLGRFALVGEALSVAATKRLKLLLFAPVACTSLEYNIRVYCLHDTHDALKEVLQLEKQLGGQLIQEPRVLHFKDSYHSLRLSIHDVPSSLWKSKVLVSYQEIPFYHIWNGTQQHLHCTFTLERVNPSTSDLACKVWVWQVEGDGQSFNINFNITKDTRFAELLALESEGGVPALVGPSAFKIPFLIRQKIITSLDPPCSRGADWRTLAQKLHLDSHLSFFASKPSPTAMLLNLWEARHFPNGNLGQLAAAVAGLGQPDAGLFTVSEAEC", "length": 842, "header": "tr|A0A8C2LJX1-1|A0A8C2LJX1_CRIGR Computationally mapped isoform of Netrin receptor UNC5 OS=Cricetulus griseus OX=10029 GN=Unc5a PE=3 SV=1 CANONICAL=A0A8C2QDI1-1" }, "locus": {} }, { "isoform_ac": "A0A8C2QDI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDI1/entry#A0A8C2QDI1-1", "sequence": { "sequence": "MAVRPGLWPAILGIVLAAWLRGSGAQQSATVASPVPGASPDLLPHFLVEPEDVYIVKNKPVLLVCKAVPATQIFFKCNGEWVRQVDHVTERSTDGSSGLPTMEVRINVSRQQVEKVFGLEEYWCQCVAWSSSGTTKSQKAYIRIAYLRKNFEQEPLAKEVSLEQGIVLPCRPPEGIPPAEVEWLRNEDLVDPSLDPNVYITREHSLVVRQARLADTANYTCVAKNIVARRRSASAAVIVYVNGGWSTWTEWSVCSASCGRGWQKRSRSCTNPAPLNGGAFCEGQNVQKTACATLCPVDGSWGSWSKWSACGLDCTHWRSRECSDPAPRNGGEECRGADLDTRNCTSDLCLHTASGPEDVALYIGLVAVAVCLILLLLVLILIYCRKKEGLDSDVADSSILTSGFQPVSIKPNKADNPHLLTIQPDLSTTTTTYQGSLCPRQDGPSPKFQLSNGHLLSPLGGGRHTLHHSSPTSEAEDFVSRLSTQNYFRTLPRGTSNMAYGTFNFLGGRLMIPNTGISLLIPPDAIPRGKIYEIYLTLHKPEDVRLPLAGCQTLLSPIVSCGPPGVLLTRPVILAMDHCGEPSPDSWSLHLKKQSCEGSWEDVLHLGEESPSHLYYCQLEAGACYVFTEQLGRFALVGEALSVAATKRLKLLLFAPVACTSLEYNIRVYCLHDTHDALKEVLQLEKQLGGQLIQEPRVLHFKDSYHSLRLSIHDVPSSLWKSKVLVSYQEIPFYHIWNGTQQHLHCTFTLERVNPSTSDLACKVWVWQVEGDGQSFNINFNITKDTRFAELLALESEGGVPALVGPSAFKIPFLIRQKIITSLDPPCSRGADWRTLAQKLHLDSHLSFFASKPSPTAMLLNLWEARHFPNGNLGQLAAAVAGLGQPDAGLFTVSEAEC", "length": 898, "header": "tr|A0A8C2QDI1-1|A0A8C2QDI1_CRIGR Isoform 1 of Netrin receptor UNC5 OS=Cricetulus griseus OX=10029 GN=Unc5a PE=3 SV=1 CANONICAL=A0A8C2QDI1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDI1/entry#A0A9J7JKX6-1", "sequence": { "sequence": "MAVRPGLWPAILGIVLAAWLRGSGAQQSATVASPVPGASPDLLPHFLVEPEDVYIVKNKPVLLVCKAVPATQIFFKCNGEWVRQVDHVTERSTDGSSAGLPTMEVRINVSRQQVEKVFGLEEYWCQCVAWSSSGTTKSQKAYIRIAYLRKNFEQEPLAKEVSLEQGIVLPCRPPEGIPPAEVEWLRNEDLVDPSLDPNVYITREHSLVVRQARLADTANYTCVAKNIVARRRSASAAVIVYVDGSWGSWSKWSACGLDCTHWRSRECSDPAPRNGGEECRGADLDTRNCTSDLCLHTASGPEDVALYIGLVAVAVCLILLLLVLILIYCRKKEGLDSDVADSSILTSGFQPVSIKPNKADNPHLLTIQPDLSTTTTTYQGSLCPRQDGPSPKFQLSNGHLLSPLGGGRHTLHHSSPTSEAEDFVSRLSTQNYFRTLPRGTSNMAYGTFNFLGGRLMIPNTGISLLIPPDAIPRGKIYEIYLTLHKPEDVRLPLAGCQTLLSPIVSCGPPGVLLTRPVILAMDHCGEPSPDSWSLHLKKQSCEGSWEDVLHLGEESPSHLYYCQLEAGACYVFTEQLGRFALVGEALSVAATKRLKLLLFAPVACTSLEYNIRVYCLHDTHDALKEVLQLEKQLGGQLIQEPRVLHFKDSYHSLRLSIHDVPSSLWKSKVLVSYQEIPFYHIWNGTQQHLHCTFTLERVNPSTSDLACKVWVWQVEGDGQSFNINFNITKDTRFAELLALESEGGVPALVGPSAFKIPFLIRQKIITSLDPPCSRGADWRTLAQKLHLDSHLSFFASKPSPTAMLLNLWEARHFPNGNLGQLAAAVAGLGQPDAGLFTVSEAEC", "length": 843, "header": "tr|A0A9J7JKX6-1|A0A8C2QDI1_CRIGR Computationally mapped isoform of Netrin receptor UNC5 OS=Cricetulus griseus OX=10029 GN=Unc5a PE=3 SV=1 CANONICAL=A0A8C2QDI1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKX6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKX6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766199", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766199", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDI1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDI1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDI1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDI1" } ], "pmid": "" }, { "name": "anterior/posterior axon guidance", "id": "GO:0033564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033564", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDI1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDI1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "netrin receptor activity", "id": "GO:0005042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005042", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDI1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 738, "end_pos": 740, "annotation": "n_glycosylation_sequon" }, { "start_pos": 781, "end_pos": 783, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QDI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDI1" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 155, "end_pos": 234, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2QDI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDI1" }, { "id": "PS51145", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51145" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZU5", "eco_id": "ECO_0000259", "start_pos": 497, "end_pos": 640, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 218, "end_pos": 220 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 738, "end_pos": 740 }, { "start_pos": 781, "end_pos": 783 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QDI3-1", "uniprot_ac": "A0A8C2QDI3", "uniprot_id": "A0A8C2QDI3_CRIGR", "mass": { "chemical_mass": 35056.0, "monoisotopic_mass": 35056.0 }, "refseq": { "ac": "XP_027281975", "name": "olfactory receptor 1468", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281975" }, "gene_names": [ { "name": "LOC100770564", "type": "recommended", "evidence": [ { "id": "A0A8C2QDI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDI3" } ] }, { "name": "LOC100770564", "type": "synonym", "evidence": [ { "id": "XP_027281975", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281975" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A8C2QDI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDI3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1468", "type": "synonym", "evidence": [ { "id": "XP_027281975", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281975" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. 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"https://www.uniprot.org/uniprotkb/A0A8C2QDJ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ8" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ8" } ], "pmid": "" }, { "name": "bleb assembly", "id": "GO:0032060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032060", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ8" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QDJ9-1", "uniprot_ac": "A0A8C2QDJ9", "uniprot_id": "A0A8C2QDJ9_CRIGR", "mass": { "chemical_mass": 96318.0, "monoisotopic_mass": 96318.0 }, "refseq": { "ac": "XP_027272026", "name": "solute carrier family 12 member 9 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272026" }, "gene_names": [ { "name": "Slc12a9", "type": "recommended", "evidence": [ { "id": "A0A8C2QDJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ9" } ] }, { "name": "Slc12a9", "type": "synonym", "evidence": [ { "id": "XP_027272026", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272026" } ] } ], "protein_names": [ { "name": "Solute carrier family 12 member 9", "type": "recommended", "evidence": [ { "id": "A0A8C2QDJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ9/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 12 member 9 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027272026", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272026" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027272026", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272026" } ] }, { "annotation": "May be an inhibitor of SLC12A1. Seems to correspond to a subunit of a multimeric transport system and thus, additional subunits may be required for its function. May play a role in lysosomal ion flux and osmoregulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JNB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNB1#function" }, { "database": "UniProtKB", "id": "ARBA00055457", "url": "https://www.uniprot.org/uniprotkb/ARBA00055457#function" }, { "database": "UniProtKB", "id": "A0A8C2QDJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc12a9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ9", "locus": {} } ], "crossref": [ { "id": "100769820", "url": "https://www.ncbi.nlm.nih.gov/gene/100769820", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004842", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004842", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769820", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769820", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QDJ9", "url": "https://www.orthodb.org/?gene=A0A8C2QDJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11827", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11827", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11827:SF98", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11827:SF98", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03522", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03522", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027272026", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272026", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QDJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QDJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNB1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASESSPLLAYRLLGEEGAAFPPNGAGGSGVASARKLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYIILALTVLSVCAIATNGAVRGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVESVLDVFGADVTGSSGIRVLPQGYGWNLLYGSLLLSLVGVVCTLGAGLYARASFLTFLLVSGSLASVLISFVAVGPRDIRLAPRPGSNASSVPPRYGHFTGFNSSTLKDNLGAGYAEDYTTGAMMTFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYILLFFLSSFTCDRTLLQEDYGFFRGISLWPPLVLIGIYATALSASMSSLIGASRILHALAQDDLFGIILAPAKVVSGGGNPWGAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHSCLLGVASCLLMMFLISPGAAGGSLLLMGLLSALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKEHVKFWRPQLLLLVGNPRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDLAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDPAFSEPAEGTREGGSPALSTLFPPPRAPGSPRALSPQDYVATVADALKMNKNVVLARACGALPPERLSRGSSSSAQLHHVDVWPLNLLRPRGGPGYVDVCGLFLLQMATILSMVPAWHSARLRIFLCLGPREAPGAAEGRLRALLSQLRIRAEVQEVVWGEGAETGEHEEEEGDFVNGGRGDEEAEALACSANALVRAQQGRGAAGGPGGPEGRDGEEGPATALTFLYLPRPPADPARYPRYLALLETLSRDLGPTLLVHGVTPVTCTDL", "length": 914, "header": "tr|A0A8C2QDJ9-1|A0A8C2QDJ9_CRIGR Isoform 1 of Solute carrier family 12 member 9 OS=Cricetulus griseus OX=10029 GN=Slc12a9 PE=3 SV=1 CANONICAL=A0A8C2QDJ9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QDJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ9/entry#A0A8C2QDJ9-1", "sequence": { "sequence": "MASESSPLLAYRLLGEEGAAFPPNGAGGSGVASARKLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYIILALTVLSVCAIATNGAVRGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVESVLDVFGADVTGSSGIRVLPQGYGWNLLYGSLLLSLVGVVCTLGAGLYARASFLTFLLVSGSLASVLISFVAVGPRDIRLAPRPGSNASSVPPRYGHFTGFNSSTLKDNLGAGYAEDYTTGAMMTFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYILLFFLSSFTCDRTLLQEDYGFFRGISLWPPLVLIGIYATALSASMSSLIGASRILHALAQDDLFGIILAPAKVVSGGGNPWGAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHSCLLGVASCLLMMFLISPGAAGGSLLLMGLLSALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKEHVKFWRPQLLLLVGNPRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDLAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDPAFSEPAEGTREGGSPALSTLFPPPRAPGSPRALSPQDYVATVADALKMNKNVVLARACGALPPERLSRGSSSSAQLHHVDVWPLNLLRPRGGPGYVDVCGLFLLQMATILSMVPAWHSARLRIFLCLGPREAPGAAEGRLRALLSQLRIRAEVQEVVWGEGAETGEHEEEEGDFVNGGRGDEEAEALACSANALVRAQQGRGAAGGPGGPEGRDGEEGPATALTFLYLPRPPADPARYPRYLALLETLSRDLGPTLLVHGVTPVTCTDL", "length": 914, "header": "tr|A0A8C2QDJ9-1|A0A8C2QDJ9_CRIGR Isoform 1 of Solute carrier family 12 member 9 OS=Cricetulus griseus OX=10029 GN=Slc12a9 PE=3 SV=1 CANONICAL=A0A8C2QDJ9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JNB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ9/entry#A0A9J7JNB1-1", "sequence": { "sequence": "MISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVESVLDVFGADVTGSSGIRVLPQGYGWNLLYGSLLLSLVGVVCTLGAGLYARASFLTFLLVSGSLASVLISFVAVGPRDIRLAPRPGSNASSVPPRYGHFTGFNSSTLKDNLGAGYAEDYTTGAMMTFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYILLFFLSSFTCDRTLLQEDYGFFRGISLWPPLVLIGIYATALSASMSSLIGASRILHALAQDDLFGIILAPAKVVSGGGNPWGAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHSCLLGVASCLLMMFLISPGAAGGSLLLMGLLSALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKEHVKFWRPQLLLLVGNPRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDLAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDPAFSEPAEGTREGGSPALSTLFPPPRAPGSPRALSPQDYVATVADALKMNKNVVLARACGALPPERLSRGSSSSAQLHHVDVWPLNLLRPRGGPGYVDVCGLFLLQMATILSMVPAWHSARLRIFLCLGPREAPGAAEGRLRALLSQLRIRAEVQEVVWGEGAETGEHEEEEGDFVNGGRGDEEAEALACSANALVRAQQGRGAAGGPGGPEGRDGEEGPATALTFLYLPRPPADPARYPRYLALLETLSRDLGPTLLVHGVTPVTCTDL", "length": 808, "header": "tr|A0A9J7JNB1-1|A0A8C2QDJ9_CRIGR Computationally mapped isoform of Solute carrier family 12 member 9 OS=Cricetulus griseus OX=10029 GN=Slc12a9 PE=3 SV=1 CANONICAL=A0A8C2QDJ9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JNB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNB1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JNB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNB1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769820", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769820", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ9" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell volume homeostasis", "id": "GO:0006884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006884", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ9" } ], "pmid": "" }, { "name": "potassium ion homeostasis", "id": "GO:0055075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055075", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ9" } ], "pmid": "" }, { "name": "chloride ion homeostasis", "id": "GO:0055064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055064", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "potassium:chloride symporter activity", "id": "GO:0015379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015379", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QDJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDJ9" }, { "id": "PF00324", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00324" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amino acid permease/ SLC12A", 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027262599", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262599" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDM3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDM3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100758317", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDM3", "locus": {} } ], "crossref": [ { "id": "cd15407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758317", "url": "https://www.ncbi.nlm.nih.gov/gene/100758317", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758317", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758317", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QDM3", "url": "https://www.orthodb.org/?gene=A0A8C2QDM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027262599", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262599", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QDM3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QDM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMFMANSSSRLSSFILLGLTNNPKLEVPLFITFTLIYLITLIGNLGMIVLIWLDSRLHTPMYLFLSNLSLADCVYSSAVTPKVMAGLLTGDKVISYGGCVAQMFFFVSFASVDCFLLAAMAFDRHAAVCKPLHYATTMTASVCTYMVIGCYVFSLAESSIYIGFIFDLSFCHSNVIHHFFCDIPPILDLSCSDIYMNEVVLFIITSFNVFFALIVILTSYAFIFIAILRMRSAEGRKKAFSTCASHLTAVTIFYGTIIFMYLQPSSSHSLDNDQMASVFYTTVVPMLNPVVYSLRNKEVHNALKKATEKMKSVQHLALVTDLCSLHN", "length": 327, "header": "tr|A0A8C2QDM3-1|A0A8C2QDM3_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100758317 PE=3 SV=1 CANONICAL=A0A8C2QDM3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QDM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDM3/entry#A0A8C2QDM3-1", "sequence": { "sequence": "MMFMANSSSRLSSFILLGLTNNPKLEVPLFITFTLIYLITLIGNLGMIVLIWLDSRLHTPMYLFLSNLSLADCVYSSAVTPKVMAGLLTGDKVISYGGCVAQMFFFVSFASVDCFLLAAMAFDRHAAVCKPLHYATTMTASVCTYMVIGCYVFSLAESSIYIGFIFDLSFCHSNVIHHFFCDIPPILDLSCSDIYMNEVVLFIITSFNVFFALIVILTSYAFIFIAILRMRSAEGRKKAFSTCASHLTAVTIFYGTIIFMYLQPSSSHSLDNDQMASVFYTTVVPMLNPVVYSLRNKEVHNALKKATEKMKSVQHLALVTDLCSLHN", "length": 327, "header": "tr|A0A8C2QDM3-1|A0A8C2QDM3_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100758317 PE=3 SV=1 CANONICAL=A0A8C2QDM3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDM3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDM3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDM3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDM3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758317", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758317", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDM3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDM3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDM3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDM3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDM3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QDM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDM3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 292, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 67, "end_pos": 69 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QDN5-1", "uniprot_ac": "A0A8C2QDN5", "uniprot_id": "A0A8C2QDN5_CRIGR", "mass": { "chemical_mass": 35081.0, "monoisotopic_mass": 35081.0 }, "refseq": { "ac": "XP_003507909", "name": "sulfotransferase 6B1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507909" }, "gene_names": [ { "name": "Sult6b1", "type": "recommended", "evidence": [ { "id": "A0A8C2QDN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDN5" } ] }, { "name": "Sult6b1", "type": "synonym", "evidence": [ { "id": "XP_003507909", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507909" } ] } ], "protein_names": [ { "name": "Sulfotransferase", "type": "recommended", "evidence": [ { "id": "A0A8C2QDN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDN5/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "A0A8C2QDN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDN5/entry#names_and_taxonomy" } ] }, { "name": "sulfotransferase 6B1", "type": "synonym", "evidence": [ { "id": "XP_003507909", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507909" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614440.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003507909", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507909" } ] }, { "annotation": "Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of thyroxine. Involved in the metabolism of thyroxine.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDN5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDN5#function" }, { "database": "UniProtKB", "id": "ARBA00059518", "url": "https://www.uniprot.org/uniprotkb/ARBA00059518#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDN5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDN5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sult6b1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDN5", "locus": {} } ], "crossref": [ { "id": "100757336", "url": "https://www.ncbi.nlm.nih.gov/gene/100757336", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757336", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757336", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EFPILEC", "url": "https://omabrowser.org/oma/group/EFPILEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QDN5", "url": "https://www.orthodb.org/?gene=A0A8C2QDN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11783", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11783", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003507909", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507909", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "26422", "url": "https://www.rhea-db.org/rhea/26422", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QDN5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QDN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADKSKFIEYIHDALEKSKETALSHLFFTYQGIPYPVTMCTSETFQALDAFEARSDDIVIASYPKCGSNWILHIVSELIFAVSKKKYTCPEFPVLECGDTEKYQRMKLFPSPRILTTHLHYDKLPQSVFKNKAKILVIFRNPKDTAASFFHFHNDVPDIPSYASWDEFFRQFIQGQVSWGSYFDFAINWNKHIDDENVKFMLYEDLKENLLAGIKQISEFLGFSLTDEQIRAVSDQSTFQAMRENSQETHGAIGPFLFRKGEVGDWKNLFNETQNQEMDERFKECLAGTSLGVKLKYESHCLA", "length": 303, "header": "tr|A0A8C2QDN5-1|A0A8C2QDN5_CRIGR Isoform 1 of Sulfotransferase OS=Cricetulus griseus OX=10029 GN=Sult6b1 PE=3 SV=1 CANONICAL=A0A8C2QDN5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QDN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDN5/entry#A0A8C2QDN5-1", "sequence": { "sequence": "MADKSKFIEYIHDALEKSKETALSHLFFTYQGIPYPVTMCTSETFQALDAFEARSDDIVIASYPKCGSNWILHIVSELIFAVSKKKYTCPEFPVLECGDTEKYQRMKLFPSPRILTTHLHYDKLPQSVFKNKAKILVIFRNPKDTAASFFHFHNDVPDIPSYASWDEFFRQFIQGQVSWGSYFDFAINWNKHIDDENVKFMLYEDLKENLLAGIKQISEFLGFSLTDEQIRAVSDQSTFQAMRENSQETHGAIGPFLFRKGEVGDWKNLFNETQNQEMDERFKECLAGTSLGVKLKYESHCLA", "length": 303, "header": "tr|A0A8C2QDN5-1|A0A8C2QDN5_CRIGR Isoform 1 of Sulfotransferase OS=Cricetulus griseus OX=10029 GN=Sult6b1 PE=3 SV=1 CANONICAL=A0A8C2QDN5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDN5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDN5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDN5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDN5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757336", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757336", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BHE6-1", "protein_name": "Sulfotransferase", "gene_name": "SULT6B1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATNSKFIDYIDEALEKSKETALSHLLFTYQGIPYPVTMCTSKTFQALDTFEARSDDIVLASYPKCGSNWILHIISELIFADSKKKFEYPEFPVLECGDPEKYKRMSQFPSPRILTTHLHYDKLPGSIFKNKAKILVIFRNPKDTAVSFFHFHNDVPDIPSYGSWDEFFRQFMKGQVSWGSYFDFAINWNKHLNDENVKLILYEDLKEDLAAGIKQIAEFFGFFPSGEQIQTISAQSTFQAMRAQSQETHGAVGPFLFRKGEVGDWRKLFSETQNQEMDEKFKECLAGTALGTKLKYDLYCQA", "length": 303 }, "evidence": [ { "id": "A0A8C2QDN5", "url": "https://omabrowser.org/oma/group/A0A8C2QDN5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0XZJ5-1", "protein_name": "Sulfotransferase", "gene_name": "SULT6B1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSQQKLVSMAEENKAFADEMNKALAKSEGFTLKDLLFSYRGTPYPVTVCSAETFQALENLEARRDDMVLVSYPKCGVNWLIQILNDLIFTTIQSKPVSAELPFIECGDPDKYQRMKQIPSPRILATHLNYDFLPKSIFKSKAKILVLFRNPKDTAVSFFHFHKNVPSVPSYNSWDEFFSEFMNGKVGWGSYFDHAVTWNKHIEDENTMIVIYEDLKENLTSGVKQIAEFFGFSPTAEQIQSIADRATFQAVKNKAQETHGAVGTVLFRKGVVGDWKNLFTEAQNQEMDAKFKACLEGTKLGAKLKYDVYCKA", "length": 312 }, "evidence": [ { "id": "A0A8C2QDN5", "url": "https://omabrowser.org/oma/group/A0A8C2QDN5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MZX9-1", "protein_name": "Sulfotransferase", "gene_name": "SULT6B1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTANSKFIDYIDEALEKSKETVLSHLFFTYQGIPYPVTMCTSETFKALDAFEARSDDIVLASYPKCGSNWILHIISELMFADSKQKYDYPEFPVLECGDPEKYQRMKQFPSPRILATHLHYDKLPGSIFKNKAKILVIFRNPKDTAVSFFHFHNDVPDIPSYGSWDDFFRQFMKGQVSWGSYFDFAINWNKHLDDENVMFILYEDLRENLATGIKRIAEFFGFSPSGEQIQTISARSTFHAMRAKSQETHGAVGPFLFRKGEVGDWKNLFSETQNQEMDEKFKECLAGTALGTKLKYNSYCQP", "length": 303 }, "evidence": [ { "id": "A0A8C2QDN5", "url": "https://omabrowser.org/oma/group/A0A8C2QDN5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "M0R952-1", "protein_name": "Sulfotransferase", "gene_name": "Sult6b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEKSKFIEYIDDALEKSKETALSQLFLTHQGIPYPVTMCTLETFRALDAFEARSDDILLASYPKCGSNWILHIVSELIFAVSKKKYACPEFPVLECGDAEKYQRMKRLPSPRILTTHLHCDKLPQSVFKSKAKILVMFRNPKDTAVSFFHFHNDVPDIPSYASWDEFFRQFIKGQVSWGSYFDFAINWNKHIDEENVKFILYEDLKENLVVGIKQISEFLGFSLTDAQIKTISAQSTFQAMRAKSQETHGAIGPFLFRKGEVGDWKSLFNETQNQEMDERFKESLAGISLGDKLKYDSYCLA", "length": 303 }, "evidence": 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"MADKSKFIEYIDEALEKSKETALSHLFFTYQGIPYPITMCTSETFQALDTFEARHDDIVLASYPKCGSNWILHIVSELIYAVSKKKYKYPEFPVLECGDSEKYQRMKGFPSPRILATHLHYDKLPGSIFENKAKILVIFRNPKDTAVSFLHFHNDVPDIPSYGSWDEFFRQFMKGQVSWGRYFDFAINWNKHLDGDNVKFILYEDLKENLAAGIKQIAEFLGFFLTGEQIQTISVQSTFQAMRAKSQDTHGAVGPFLFRKGEVGDWKNLFSEIQNQEMDEKFKECLAGTSLGAKLKYESYCQG", "length": 303 }, "evidence": [ { "id": "A0A8C2QDN5", "url": "https://omabrowser.org/oma/group/A0A8C2QDN5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8L5A7-1", "protein_name": "Cytosolic sulfotransferase 15", "gene_name": "SOT15", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATSSMKSIPMAIPSFSMCHKLELLKEGKTRDVPKAEEDEGLSCEFQEMLDSLPKERGWRTRYLYLFQGFWCQAKEIQAIMSFQKHFQSLENDVVLATIPKSGTTWLKALTFTILNRHRFDPVASSTNHPLFTSNPHDLVPFFEYKLYANGDVPDLSGLASPRTFATHLPFGSLKETIEKPGVKVVYLCRNPFDTFISSWHYTNNIKSESVSPVLLDQAFDLYCRGVIGFGPFWEHMLGYWRESLKRPEKVFFLRYEDLKDDIETNLKRLATFLELPFTEEEERKGVVKAIAELCSFENLKKLEVNKSNKSIKNFENRFLFRKGEVSDWVNYLSPSQVERLSALVDDKLGGSGLTFRLS", "length": 359 }, "evidence": [ { "id": "A0A8C2QDN5", "url": "https://omabrowser.org/oma/group/A0A8C2QDN5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "sulfotransferase activity", "id": "GO:0008146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008146", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDN5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDN5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDN5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "26422", "name": "", "equation": "thyroxine + 3'-phosphoadenylyl sulfate = thyroxine sulfate + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8C2QDN5-1" ], "evidence": [ { "id": "26422", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/26422" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8C2QDN5", "gene_name": "Sult6b1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0A8C2QDN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDN5" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QDN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDN5" }, { "id": "PF00685", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfotransferase", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 289, "start_aa": "Asp", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 271, "end_pos": 273 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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"title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QDP0-1", "uniprot_ac": "A0A8C2QDP0", "uniprot_id": "A0A8C2QDP0_CRIGR", "mass": { "chemical_mass": 35064.0, "monoisotopic_mass": 35064.0 }, "refseq": { "ac": "XP_027268043", "name": "olfactory receptor 145", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268043" }, "gene_names": [ { "name": "LOC100760648", "type": "recommended", "evidence": [ { "id": "A0A8C2QDP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDP0" } ] }, { "name": "LOC100760648", "type": "synonym", "evidence": [ { "id": "XP_027268043", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268043" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A8C2QDP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDP0/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 145", "type": "synonym", "evidence": [ { "id": "XP_027268043", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268043" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268043", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268043" } ] }, { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDP0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDP0#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDP0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDP0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100760648", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDP0", "locus": {} } ], "crossref": [ { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760648", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760648", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WYVLTSM", "url": "https://omabrowser.org/oma/group/WYVLTSM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QDP0", "url": "https://www.orthodb.org/?gene=A0A8C2QDP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268043", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268043", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QDP0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QDP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLTNSSLVTEFILLGLTDNPDLQIPLFLVFLVMYMITALGNLTLILLIVLNSHLHTPMYFFLFNLSFIDLCYSSVVTPKMLMNFVLEKNIIGFAGCMTQLYFFCFFVISECYVLTAMAYDRYVAICNPLMYNVVMSPKVCSYLMLGSYLMGFFDAMIHTGCILRLIFCDGNIINHYFCDLLPLMKLSCTSTYVNEIEIFIVGGKDITVPSIVIFISYGFILSSILQIRSTTGRSKAFSTCSSHIIAVSLFFGSCAFMYLKPSSVGTLNEGKVSSVFYNIVVPMMNPLIYSLRNKDVKIALRKTLKRRKF", "length": 310, "header": "tr|A0A8C2QDP0-1|A0A8C2QDP0_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100760648 PE=3 SV=1 CANONICAL=A0A8C2QDP0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QDP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDP0/entry#A0A8C2QDP0-1", "sequence": { "sequence": "MVLTNSSLVTEFILLGLTDNPDLQIPLFLVFLVMYMITALGNLTLILLIVLNSHLHTPMYFFLFNLSFIDLCYSSVVTPKMLMNFVLEKNIIGFAGCMTQLYFFCFFVISECYVLTAMAYDRYVAICNPLMYNVVMSPKVCSYLMLGSYLMGFFDAMIHTGCILRLIFCDGNIINHYFCDLLPLMKLSCTSTYVNEIEIFIVGGKDITVPSIVIFISYGFILSSILQIRSTTGRSKAFSTCSSHIIAVSLFFGSCAFMYLKPSSVGTLNEGKVSSVFYNIVVPMMNPLIYSLRNKDVKIALRKTLKRRKF", "length": 310, "header": "tr|A0A8C2QDP0-1|A0A8C2QDP0_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100760648 PE=3 SV=1 CANONICAL=A0A8C2QDP0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDP0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDP0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035299289", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299289" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDP2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Col26a1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDP2", "locus": {} } ], "crossref": [ { "id": "100768133", "url": "https://www.ncbi.nlm.nih.gov/gene/100768133", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" 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"tr|A0A8C2QDT7-1|A0A8C2QDT7_CRIGR Isoform 1 of Protein Jade-3 isoform X4 OS=Cricetulus griseus OX=10029 GN=Jade3 PE=3 SV=1 CANONICAL=A0A8C2QDT7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 92, "start_aa": "Thr", "end_pos": 92, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr92", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271113", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271113" } ] }, { "annotation": "Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P. Plays a role in negative regulation of lipid biosynthesis. Negatively regulates APOB secretion from hepatocytes. Binds cholesterol and acidic phospholipids. Also binds 25-hydroxycholesterol. Binds phosphatidylserine.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JQL7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQL7#function" }, { "database": "UniProtKB", "id": "ARBA00060258", "url": "https://www.uniprot.org/uniprotkb/ARBA00060258#function" }, { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Osbpl10", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9", "locus": {} } ], "crossref": [ { "id": "cd13291", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13291", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751799", "url": "https://www.ncbi.nlm.nih.gov/gene/100751799", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751799", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751799", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QDT9", "url": "https://www.orthodb.org/?gene=A0A8C2QDT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271113", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271113", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QDT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQL7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERATQSADSGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVAGRSAAVGLGGGGSRSSPGSVAASPSGGGGRRREPALEGVLSKYTNLLQGWQNRYFVLDFEAGLLQYFVNEQSKHQKPRGVLALSGAIVSLSDEAPHMLVVYSANGEMYKLRAADAKERQFWVTQLRACAKYHMEINSKTAPSSRSRSLTLLPHGTPNSASPCSQRHLSAGAPGVVSVTHHKSPAAARRAKSQYSGQLHEVREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLGECLTLLQQSVRQAGPPSHKPGSSETILGWHGPTSHSTDQLKNGTLGSLPSASANITWAILPNSSEEEHGSQPEPEPNSGPELVLSEEEQSDNEDKEETELGAMDDQRSVILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVISFVEYYLTAFHEGRKGTLAKKPYNPIIGETFHCSWEVPKDRVKSKRTSPHSISCHEHPMTEDPCKSYKLRFVAEQVSHHPPISCFYCECKEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLDHGEDYVFTLPSAYARSILTVPWVELGGKVNINCAKTGYSATVTFHTKPFYGGKVHRVTAEVKHNPTNTIICKAHGEWNGTLEFTYSNGETKVIDTTALPVYPKKLRPLEKQGPMESRNLWQEVTHYLRLGDIDAATEHKRRLEEKQRMEERKRETLRTPWQPKYFIPEGDGWVYFNPLWKTH", "length": 764, "header": "tr|A0A8C2QDT9-1|A0A8C2QDT9_CRIGR Isoform 1 of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbpl10 PE=3 SV=1 CANONICAL=A0A8C2QDT9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QDT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9/entry#A0A8C2QDT9-1", "sequence": { "sequence": "MERATQSADSGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVAGRSAAVGLGGGGSRSSPGSVAASPSGGGGRRREPALEGVLSKYTNLLQGWQNRYFVLDFEAGLLQYFVNEQSKHQKPRGVLALSGAIVSLSDEAPHMLVVYSANGEMYKLRAADAKERQFWVTQLRACAKYHMEINSKTAPSSRSRSLTLLPHGTPNSASPCSQRHLSAGAPGVVSVTHHKSPAAARRAKSQYSGQLHEVREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLGECLTLLQQSVRQAGPPSHKPGSSETILGWHGPTSHSTDQLKNGTLGSLPSASANITWAILPNSSEEEHGSQPEPEPNSGPELVLSEEEQSDNEDKEETELGAMDDQRSVILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVISFVEYYLTAFHEGRKGTLAKKPYNPIIGETFHCSWEVPKDRVKSKRTSPHSISCHEHPMTEDPCKSYKLRFVAEQVSHHPPISCFYCECKEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLDHGEDYVFTLPSAYARSILTVPWVELGGKVNINCAKTGYSATVTFHTKPFYGGKVHRVTAEVKHNPTNTIICKAHGEWNGTLEFTYSNGETKVIDTTALPVYPKKLRPLEKQGPMESRNLWQEVTHYLRLGDIDAATEHKRRLEEKQRMEERKRETLRTPWQPKYFIPEGDGWVYFNPLWKTH", "length": 764, "header": "tr|A0A8C2QDT9-1|A0A8C2QDT9_CRIGR Isoform 1 of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbpl10 PE=3 SV=1 CANONICAL=A0A8C2QDT9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9/entry#A0A9J7JQL7-1", "sequence": { "sequence": "MERATQSADSGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVAGRSAAVGLGGGGSRSSPGSVAASPSGGGGRRREPALEGVLSKYTNLLQGWQNRYFVLDFEAGLLQYFVNEQSKHQKPRGVLALSGAIVSLSDEAPHMLVVYSANGEMYKLRAADAKERQFWVTQLRACAKYHMEINSKMMNQVEGQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLGECLTLLQQSVRQAGPPSHKPGSSETILGWHGPTSHSTDQLKNGTLGSLPSASANITWAILPNSSEEEHGSQPEPEPNSGPELVLSEEEQSDNEDKEETELGAMDDQRSVILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVISFVEYYLTAFHEGRKGTLAKKPYNPIIGETFHCSWEVPKDRVKSKRTSPHSISCHEHPMTEDPCKSYKLRFVAEQVSHHPPISCFYCECKEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLDHGEDYVFTLPSAYARSILTVPWVELGGKVNINCAKTGYSATVTFHTKPFYGGKVHRVTAEVKHNPTNTIICKAHGEWNGTLEFTYSNGETKVIDTTALPVYPKKLRPLEKQGPMESRNLWQEVTHYLRLGDIDAATEHKRRLEEKQRMEERKRETLRTPWQPKYFIPEGDGWVYFNPLWKTH", "length": 700, "header": "tr|A0A9J7JQL7-1|A0A8C2QDT9_CRIGR Computationally mapped isoform of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbpl10 PE=3 SV=1 CANONICAL=A0A8C2QDT9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JQL7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQL7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JQL7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQL7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751799", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751799", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" } ], "pmid": "" }, { "name": "endoplasmic reticulum-endosome membrane contact site", "id": "GO:0140284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140284", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" } ], "pmid": "" }, { "name": "endoplasmic reticulum-trans-Golgi network membrane contact site", "id": "GO:0160258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160258", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" } ], "pmid": "" }, { "name": "phospholipid transfer to membrane", "id": "GO:0006649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006649", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" } ], "pmid": "" }, { "name": "phospholipid homeostasis", "id": "GO:0055091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055091", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" } ], "pmid": "" }, { "name": "lysosomal membrane organization", "id": "GO:0097212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097212", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" } ], "pmid": "" }, { "name": "phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity", "id": "GO:0160270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160270", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 660, "end_pos": 662, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QDT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDT9" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 172, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 16, "end_pos": 18 }, { "start_pos": 333, "end_pos": 335 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 353, "end_pos": 355 }, { "start_pos": 660, "end_pos": 662 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QDW6-1", "uniprot_ac": "A0A8C2QDW6", "uniprot_id": "A0A8C2QDW6_CRIGR", "mass": { "chemical_mass": 109940.0, "monoisotopic_mass": 109940.0 }, "refseq": { "ac": "XP_003511202", "name": "PHD finger protein 12 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511202" }, "gene_names": [ { "name": "Phf12", "type": "recommended", "evidence": [ { "id": "A0A8C2QDW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6" } ] }, { "name": "Phf12", "type": "synonym", "evidence": [ { "id": "XP_003511202", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511202" } ] } ], "protein_names": [ { "name": "PHD finger protein 12", "type": "recommended", "evidence": [ { "id": "A0A8C2QDW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6/entry#names_and_taxonomy" } ] }, { "name": "PHD factor 1", "type": "synonym", "evidence": [ { "id": "A0A8C2QDW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6/entry#names_and_taxonomy" } ] }, { "name": "PHD finger protein 12 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003511202", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511202" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases assembly gap :: added 513 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615038.1) and transcript sequence (IACG01029534.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003511202.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003511202", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511202" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDW6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Phf12", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6", "locus": {} } ], "crossref": [ { "id": "cd15533", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15533", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15534", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15534", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22703", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22703", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767411", "url": "https://www.ncbi.nlm.nih.gov/gene/100767411", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031966", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031966", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767411", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767411", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QDW6", "url": "https://www.orthodb.org/?gene=A0A8C2QDW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46309", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46309", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46309:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46309:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16737", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16737", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003511202", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511202", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QDW6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QDW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWEKMETKTIVYDLDTSGGLMEQIQALLAPPKTDETEKRSRKPEKESRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQKKELGHVNGLVDKSSKRTTSPSSDTDLLDRSASKTELKAIAHARILERRASRPGTPTSNASTETPTSEHNDVDEDIIDVDEEPVATEPDYVQPQLRRPFELLIAAAMERNPTQFQLPNELTCTTALPGSSKRRRKEETTGKNVKRTQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNLTLSNRCQVFDRFQDTISQHVVKVDFLNRIHKKHPPNRRVLQSVKRRSLKVPDAIKSQYQFPPPLIAPAAIRDGELICNGIPEESQMHLLNSEHLATQAEQQEWLCSVVALQCSILKHLSAKQMPSHWDSEQTEKADIKPVIVTDSSITTSLQTADKAPLPSHYPLSCPSAVSTQNSLGCSPPHQPPALEDISCSSCVEKSKKTPCGTANGPVNTEVKANGPHLYNSPTDSTDPRRLPGANTPLPSLSHRQGWPRPLTPPSAGGLQNHTVGIIVKTENATGPSSCPQRSLVPVPSLPPSVPSSCASIENTSTLHRKTVQSQIGPSLTDSRSLGSPPNATRVLTPPQAAGDSILATGPNQRFCSPAPSSDGKVSPGTLSIGSALTVPSFPANSTAMVDLTNSLRAFMDVNGEIEINMLDEKLIKFLALQRIHQLFPSRVQASPGSVGTHPLTSGGHHTEVQRKEVQARAVFYPLLGLGGAVNMCYRTLYIGTGADMDVCLTNYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSEKTPPTPPSSIVAKVQSVIRRRRHQKQDEEPSEEAAMMSSQAQGPQRRPCNCKASSSSLIGGSGAGWEGTALLHHGSYIKLGCLQFVFSITEFATKQPKGDASLLQDGVLTEKLSLKPHQGPVLRSNSVP", "length": 1004, "header": "tr|A0A8C2QDW6-1|A0A8C2QDW6_CRIGR Isoform 1 of PHD finger protein 12 OS=Cricetulus griseus OX=10029 GN=Phf12 PE=4 SV=1 CANONICAL=A0A8C2QDW6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QDW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6/entry#A0A8C2QDW6-1", "sequence": { "sequence": "MWEKMETKTIVYDLDTSGGLMEQIQALLAPPKTDETEKRSRKPEKESRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQKKELGHVNGLVDKSSKRTTSPSSDTDLLDRSASKTELKAIAHARILERRASRPGTPTSNASTETPTSEHNDVDEDIIDVDEEPVATEPDYVQPQLRRPFELLIAAAMERNPTQFQLPNELTCTTALPGSSKRRRKEETTGKNVKRTQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNLTLSNRCQVFDRFQDTISQHVVKVDFLNRIHKKHPPNRRVLQSVKRRSLKVPDAIKSQYQFPPPLIAPAAIRDGELICNGIPEESQMHLLNSEHLATQAEQQEWLCSVVALQCSILKHLSAKQMPSHWDSEQTEKADIKPVIVTDSSITTSLQTADKAPLPSHYPLSCPSAVSTQNSLGCSPPHQPPALEDISCSSCVEKSKKTPCGTANGPVNTEVKANGPHLYNSPTDSTDPRRLPGANTPLPSLSHRQGWPRPLTPPSAGGLQNHTVGIIVKTENATGPSSCPQRSLVPVPSLPPSVPSSCASIENTSTLHRKTVQSQIGPSLTDSRSLGSPPNATRVLTPPQAAGDSILATGPNQRFCSPAPSSDGKVSPGTLSIGSALTVPSFPANSTAMVDLTNSLRAFMDVNGEIEINMLDEKLIKFLALQRIHQLFPSRVQASPGSVGTHPLTSGGHHTEVQRKEVQARAVFYPLLGLGGAVNMCYRTLYIGTGADMDVCLTNYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSEKTPPTPPSSIVAKVQSVIRRRRHQKQDEEPSEEAAMMSSQAQGPQRRPCNCKASSSSLIGGSGAGWEGTALLHHGSYIKLGCLQFVFSITEFATKQPKGDASLLQDGVLTEKLSLKPHQGPVLRSNSVP", "length": 1004, "header": "tr|A0A8C2QDW6-1|A0A8C2QDW6_CRIGR Isoform 1 of PHD finger protein 12 OS=Cricetulus griseus OX=10029 GN=Phf12 PE=4 SV=1 CANONICAL=A0A8C2QDW6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 880, "start_aa": "Thr", "end_pos": 880, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr880", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDW6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDW6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767411", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767411", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDW6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDW6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDW6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDW6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDW6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDW6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6" } ], "pmid": "" }, { "name": "Sin3-type complex", "id": "GO:0070822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070822", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDW6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" }, { "start_pos": 606, "end_pos": 608, "annotation": "n_glycosylation_sequon" }, { "start_pos": 637, "end_pos": 639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" }, { "start_pos": 719, "end_pos": 721, "annotation": "n_glycosylation_sequon" }, { "start_pos": 856, "end_pos": 858, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QDW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6" }, { "id": "PS50006", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50006" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FHA", "eco_id": "ECO_0000259", "start_pos": 815, "end_pos": 869, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2QDW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW6" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 105, "start_aa": "His", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 880 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 170, "end_pos": 172 }, { "start_pos": 278, "end_pos": 280 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 595, "end_pos": 597 }, { "start_pos": 606, "end_pos": 608 }, { "start_pos": 637, "end_pos": 639 }, { "start_pos": 665, "end_pos": 667 }, { "start_pos": 719, "end_pos": 721 }, { "start_pos": 856, "end_pos": 858 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QDX9-1", "uniprot_ac": "A0A8C2QDX9", "uniprot_id": "A0A8C2QDX9_CRIGR", "mass": { "chemical_mass": 52682.0, "monoisotopic_mass": 52682.0 }, "refseq": { "ac": "XP_027267112", "name": "casein kinase I isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267112" }, "gene_names": [ { "name": "Csnk1g1", "type": "recommended", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] }, { "name": "Csnk1g1", "type": "synonym", "evidence": [ { "id": "XP_027267112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267112" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9/entry#names_and_taxonomy" } ] }, { "name": "casein kinase I isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027267112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267112" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267112", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267112" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDX9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Csnk1g1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9", "locus": {} } ], "crossref": [ { "id": "cd14126", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14126", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774663", "url": "https://www.ncbi.nlm.nih.gov/gene/100774663", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774663", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774663", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QDX9", "url": "https://www.orthodb.org/?gene=A0A8C2QDX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FW68", "url": "https://www.orthodb.org/?gene=A0A9J7FW68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11909", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11909", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027267112", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267112", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QDX9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QDX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRS3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FW68", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FW68-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GUG2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GUG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GUG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GUG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K865", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K865", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K865-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K865-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDHSNREKDDRQRSTKTMAQRNTHCSRPSGTSASSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSTGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFERKGYTFDYAYDWVGRPIPTPVGAVHVDSGASAITRESHTHRDRPSQQQPLRNQTASSERRGEWEIQPSRQTNTSFLTSHLAADRHGGSVQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKKTAQRHK", "length": 459, "header": "tr|A0A8C2QDX9-1|A0A8C2QDX9_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Csnk1g1 PE=3 SV=1 CANONICAL=A0A8C2QDX9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QDX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9/entry#A0A8C2QDX9-1", "sequence": { "sequence": "MDHSNREKDDRQRSTKTMAQRNTHCSRPSGTSASSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSTGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFERKGYTFDYAYDWVGRPIPTPVGAVHVDSGASAITRESHTHRDRPSQQQPLRNQTASSERRGEWEIQPSRQTNTSFLTSHLAADRHGGSVQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKKTAQRHK", "length": 459, "header": "tr|A0A8C2QDX9-1|A0A8C2QDX9_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Csnk1g1 PE=3 SV=1 CANONICAL=A0A8C2QDX9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FRS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9/entry#A0A9J7FRS3-1", "sequence": { "sequence": "MDHSNREKDDRQRSTKTMAQRNTHCSRPSGTSASSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSTGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFERKGYTFDYAYDWVGRPIPTPVGAVHVDSGASAITRESHTHRDRPSQQQPLRNQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKKTAQRHK", "length": 422, "header": "tr|A0A9J7FRS3-1|A0A8C2QDX9_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Csnk1g1 PE=3 SV=1 CANONICAL=A0A8C2QDX9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FW68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9/entry#A0A9J7FW68-1", "sequence": { "sequence": "MDHSNREKDDRQRSTKTMAQRNTHCSRPSGTSASSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSTEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFERKGYTFDYAYDWVGRPIPTPVGAVHVDSGASAITRESHTHRDRPSQQQPLRNQTASSERRGEWEIQPSRQTNTSFLTSHLAADRHGGSVQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKKTAQRHK", "length": 330, "header": "tr|A0A9J7FW68-1|A0A8C2QDX9_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Csnk1g1 PE=3 SV=1 CANONICAL=A0A8C2QDX9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GUG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9/entry#A0A9J7GUG2-1", "sequence": { "sequence": "MDHSNREKDDRQRSTKTMAQRNTHCSRPSGTSASSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSTGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFERKGYTFDYAYDWVGRPIPTPVGAVHVDSGASAITRESHTHRDRPSQQQPLRNQTASSERRGEWEIQPSRQTNTSFLTSHLAADRHGGSVQEVKTPLAL", "length": 414, "header": "tr|A0A9J7GUG2-1|A0A9J7GUG2_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Csnk1g1 PE=3 SV=1 CANONICAL=A0A8C2QDX9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GVG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9/entry#A0A9J7GVG9-1", "sequence": { "sequence": "MDHSNREKDDRQRSTKTMAQRNTHCSRPSGTSASSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSTGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFERKGYTFDYAYDWVGRPIPTPVGAVHVDSGASAITRESHTHRDRPSQQQPLRNQTASSERRGEWEIQPSRQTNTSFLTSHLAADRHGGSVQPRSLTADWFVRGPFSHSPAPT", "length": 427, "header": "tr|A0A9J7GVG9-1|A0A9J7GVG9_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Csnk1g1 PE=3 SV=1 CANONICAL=A0A8C2QDX9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K865-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9/entry#A0A9J7K865-1", "sequence": { "sequence": "MVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFERKGYTFDYAYDWVGRPIPTPVGAVHVDSGASAITRESHTHRDRPSQQQPLRNQTASSERRGEWEIQPSRQTNTSFLTSHLAADRHGGSVQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKKTAQRHK", "length": 344, "header": "tr|A0A9J7K865-1|A0A8C2QDX9_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Csnk1g1 PE=3 SV=1 CANONICAL=A0A8C2QDX9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRS3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRS3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRS3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRS3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774663", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774663", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDX9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDX9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDX9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QDX9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", "A0A8C2QND0-1", "G3HXQ8-1", "G3I724-1", "A0A8C2M0A2-1", "A0A9J7K2S5-1", "A0A8C2MMZ5-1", "A0A8C2QH69-1", "A0A8C2QL63-1", "A0A9J7K953-1", "A0A9J7G3C1-1", "A0A9J7GFS3-1", "A0A9J7JBH0-1", "A0A9J7FGD3-1", "A0A9J7FKM1-1", "A0A9J7JKJ1-1", "A0A9J7G180-1", "A0A9J7JTL3-1", "A0A9J7GQ42-1", "A0A9J7EZ53-1", "A0A9J7J5Z8-1", "A0A9J7EVK4-1", "A0A9J7F0G6-1", "A0A9J7FCC7-1", "A0A9J7K3S4-1", "A0A9J7GAF4-1", "A0A9J7GBF4-1", "A0A8C2MTI7-1", "A0A9J7J1N3-1", "A0A9J7F4P4-1", "A0A9J7JNU2-1", "A0A9J7FZY8-1", "A0A9J7H3M5-1", "A0A9J7JJV6-1", "A0A9J7GJE4-1", "A0A8C2LY52-1", "A0A9J7H8U3-1", "A0A9J7F821-1", "A0A8C2N185-1", "A0A9J7KFV8-1", "A0A8C2MQM0-1", "A0A8C2N310-1", "A0A9J7J6H1-1", "A0A9J7H2P9-1", "A0A9J7H4N5-1", "A0A3L7GPC7-1", "A0A9J7H6V8-1", "A0A3L7HV37-1", "A0A8C2LTZ7-1", "A0A9J7K7D8-1", "A0A8C2LDU9-1", "A0A8C2LTW4-1", "A0A9J7JAM4-1", "A0A9J7JXM2-1", "A0A9J7JRJ8-1", "A0A8C2QEB8-1", "A0A3L7HKC4-1", "A0A8C2LI14-1", "A0A8C2QDX9-1", "A0A9J7G1D9-1", "A0A9J7F985-1", "A0A8C2MCX3-1", "A0A8C2MEU5-1", "A0A8C2MFN1-1", "A0A8C2MMI4-1", "A0A9J7JAB2-1", "A0A9J7G969-1", "A0A8C2MQ42-1", "A0A8C2MR08-1", "A0A8C2MUQ5-1", "A0A9J7FZA7-1", "A0A8C2N3C9-1", "A0A8C2N6L4-1", "A0A8C2N9X1-1", 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"evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3HX91-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", 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"A0A9J7H8W5-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7H540-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H949-1", "A0A9J7GQY0-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] }, { "ec_number": "2.7.11.1", "activity": "", 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"activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] } ] }, { "uniprot_ac": "A0A9J7F0J6", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] } ] }, { "uniprot_ac": "A0A9J7F1D2", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1D2" } ] } ] }, { "uniprot_ac": "A0A9J7F2F1", "gene_name": "Prkcd", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F821", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] } ] }, { "uniprot_ac": "A0A9J7F8T0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] } ] }, { "uniprot_ac": "A0A9J7G5N9", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] } ] }, { "uniprot_ac": "A0A9J7G8N4", "gene_name": "Sgk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] } ] }, { "uniprot_ac": "A0A9J7G969", "gene_name": "LOC100754771", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] } ] }, { "uniprot_ac": "A0A9J7G9D1", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] } ] }, { "uniprot_ac": "A0A9J7GAB0", "gene_name": "Pkn3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] } ] }, { "uniprot_ac": "A0A9J7GAF4", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBI2", "gene_name": "LOC100771767", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] } ] }, { "uniprot_ac": "A0A9J7GBL6", "gene_name": "Ttbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] } ] }, { "uniprot_ac": "A0A9J7GD76", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] } ] }, { "uniprot_ac": "A0A9J7GES8", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] } ] }, { "uniprot_ac": "A0A9J7GF59", "gene_name": "LOC103160391", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": 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= O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JQZ1", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] } ] }, { "uniprot_ac": "A0A9J7JRI3", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003512945", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512945" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE02", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE02" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Aif1l", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE02", "locus": {} } ], "crossref": [ { "id": "100752261", "url": "https://www.ncbi.nlm.nih.gov/gene/100752261", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752261", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752261", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MDFGMSV", "url": "https://omabrowser.org/oma/group/MDFGMSV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QE02", "url": "https://www.orthodb.org/?gene=A0A8C2QE02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10356", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10356", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10356:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10356:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003512945", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512945", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QE02", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QE02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVAVGNRFQGGKAFGLLKARQEKRLEEINREFLCDQKFSDEENLPEKLAAFKEKYMEFDLNNEGEIDLMSLKRMMEKLGVPKTHLEMKKMISEVTGGVSDTISYRDFVNMMLGKRSAVLKLVMMFEGKAHESSSKPAGPPPERDIASLP", "length": 150, "header": "tr|A0A8C2QE02-1|A0A8C2QE02_CRIGR Isoform 1 of Allograft inflammatory factor 1-like OS=Cricetulus griseus OX=10029 GN=Aif1l PE=4 SV=1 CANONICAL=A0A8C2QE02-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QE02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE02/entry#A0A8C2QE02-1", "sequence": { "sequence": "MSVAVGNRFQGGKAFGLLKARQEKRLEEINREFLCDQKFSDEENLPEKLAAFKEKYMEFDLNNEGEIDLMSLKRMMEKLGVPKTHLEMKKMISEVTGGVSDTISYRDFVNMMLGKRSAVLKLVMMFEGKAHESSSKPAGPPPERDIASLP", "length": 150, "header": "tr|A0A8C2QE02-1|A0A8C2QE02_CRIGR Isoform 1 of Allograft inflammatory factor 1-like OS=Cricetulus griseus OX=10029 GN=Aif1l PE=4 SV=1 CANONICAL=A0A8C2QE02-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE02", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE02" } ], "pmid": "" }, { "name": "ruffle assembly", "id": "GO:0097178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097178", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE02", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QE02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE02" }, { "id": "PS50222", "database": "PROSITE", "url": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QE16-1", "uniprot_ac": "A0A8C2QE16", "uniprot_id": "A0A8C2QE16_CRIGR", "mass": { "chemical_mass": 12465.0, "monoisotopic_mass": 12465.0 }, "refseq": { "ac": "XP_035298562", "name": "elongin-C-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298562" }, "gene_names": [ { "name": "LOC100766274", "type": "recommended", "evidence": [ { "id": "A0A8C2QE16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE16" } ] }, { "name": "LOC100766274", "type": "synonym", "evidence": [ { "id": "XP_035298562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298562" } ] } ], "protein_names": [ { "name": "Elongin-C", "type": "recommended", "evidence": [ { "id": "A0A8C2QE16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE16/entry#names_and_taxonomy" } ] }, { "name": "Elongin 15 kDa subunit", "type": "synonym", "evidence": [ { "id": "A0A8C2QE16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE16/entry#names_and_taxonomy" } ] }, { "name": "RNA polymerase II transcription factor SIII subunit C", "type": "synonym", "evidence": [ { "id": "A0A8C2QE16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE16/entry#names_and_taxonomy" } ] }, { "name": "SIII p15", "type": "synonym", "evidence": [ { "id": "A0A8C2QE16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE16/entry#names_and_taxonomy" } ] }, { "name": "Stromal membrane-associated protein SMAP1B homolog", "type": "synonym", "evidence": [ { "id": "A0A8C2QE16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE16/entry#names_and_taxonomy" } ] }, { "name": "Transcription elongation factor B polypeptide 1", "type": "synonym", "evidence": [ { "id": "A0A8C2QE16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE16/entry#names_and_taxonomy" } ] }, { "name": "elongin-C-like", "type": "synonym", "evidence": [ { "id": "XP_035298562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298562" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613661.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035298562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298562" } ] }, { "annotation": "SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. 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"A0A8C2QE55-1", "uniprot_ac": "A0A8C2QE55", "uniprot_id": "A0A8C2QE55_CRIGR", "mass": { "chemical_mass": 58186.0, "monoisotopic_mass": 58186.0 }, "refseq": { "ac": "XP_003510909", "name": "mitochondrial-processing peptidase subunit alpha isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510909" }, "gene_names": [ { "name": "Pmpca", "type": "recommended", "evidence": [ { "id": "A0A8C2QE55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55" } ] }, { "name": "Pmpca", "type": "synonym", "evidence": [ { "id": "XP_003510909", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510909" } ] } ], "protein_names": [ { "name": "Mitochondrial-processing peptidase subunit alpha", "type": "recommended", "evidence": [ { "id": "A0A8C2QE55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55/entry#names_and_taxonomy" } ] }, { "name": "Alpha-MPP", "type": "synonym", "evidence": [ { "id": "A0A8C2QE55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55/entry#names_and_taxonomy" } ] }, { "name": "Inactive zinc metalloprotease alpha", "type": "synonym", "evidence": [ { "id": "A0A8C2QE55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial-processing peptidase subunit alpha isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003510909", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510909" } ] }, { "name": "p-55", "type": "synonym", "evidence": [ { "id": "A0A8C2QE55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 68 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614977.1) and transcript sequence (IACG01009489.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003510909.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510909", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510909" } ] }, { "annotation": "Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JW74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW74#function" }, { "database": "UniProtKB", "id": "ARBA00002123", "url": "https://www.uniprot.org/uniprotkb/ARBA00002123#function" }, { "database": "UniProtKB", "id": "A0A8C2QE55", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE55", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pmpca", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55", "locus": {} } ], "crossref": [ { "id": "100761595", "url": "https://www.ncbi.nlm.nih.gov/gene/100761595", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761595", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761595", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QE55", "url": "https://www.orthodb.org/?gene=A0A8C2QE55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11851", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11851", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11851:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11851:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00675", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00675", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510909", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510909", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QE55", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QE55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JW74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JW74-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW74-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATAVWAAARLLRGSAVRCARPRFGPPAHRRFSSGATYPNIPLSSPLPGVPKPVFATVDGQEKFETKVTTLDNGLRVASQNKFGQFCTVGILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVGLLADVVLHPCLTDEEIEMTRMTVQFELEDLNMRPDPEPLLTEMIHEAAFRENTVGLHRFCPAENIAKIDREVLHSYLKNYYTPDRMVLAGVGVEHEHLVECARKYLLGAQPAWGATGAVDVDRSVAQYTGGIVKVERDMSNVSLGPTPIPELTHIMVGLESCSFLEDDFIPFAVLNMMMGGGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGRTVDLVELERAKTQLMSMLMMNLESRPVIFEDVGRQVLATHSRKLPHELCTLIRNVKPEDIKRVASKMLRGKPAVAALGDLTDLPTYDHIQAALASRDGRLPRTYRLFR", "length": 524, "header": "tr|A0A8C2QE55-1|A0A8C2QE55_CRIGR Isoform 1 of Mitochondrial-processing peptidase subunit alpha OS=Cricetulus griseus OX=10029 GN=Pmpca PE=3 SV=1 CANONICAL=A0A8C2QE55-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QE55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55/entry#A0A8C2QE55-1", "sequence": { "sequence": "MATAVWAAARLLRGSAVRCARPRFGPPAHRRFSSGATYPNIPLSSPLPGVPKPVFATVDGQEKFETKVTTLDNGLRVASQNKFGQFCTVGILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVGLLADVVLHPCLTDEEIEMTRMTVQFELEDLNMRPDPEPLLTEMIHEAAFRENTVGLHRFCPAENIAKIDREVLHSYLKNYYTPDRMVLAGVGVEHEHLVECARKYLLGAQPAWGATGAVDVDRSVAQYTGGIVKVERDMSNVSLGPTPIPELTHIMVGLESCSFLEDDFIPFAVLNMMMGGGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGRTVDLVELERAKTQLMSMLMMNLESRPVIFEDVGRQVLATHSRKLPHELCTLIRNVKPEDIKRVASKMLRGKPAVAALGDLTDLPTYDHIQAALASRDGRLPRTYRLFR", "length": 524, "header": "tr|A0A8C2QE55-1|A0A8C2QE55_CRIGR Isoform 1 of Mitochondrial-processing peptidase subunit alpha OS=Cricetulus griseus OX=10029 GN=Pmpca PE=3 SV=1 CANONICAL=A0A8C2QE55-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JW74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55/entry#A0A9J7JW74-1", "sequence": { "sequence": "MKRNILVELLIFWKNWHFRLLLDLTAKMKFCLRWKSMVVSVTARPQDTTMYAVSADSKGLDTVVGLLADVVLHPCLTDEEIEMTRMTVQFELEDLNMRPDPEPLLTEMIHEAAFRENTVGLHRFCPAENIAKIDREVLHSYLKNYYTPDRMVLAGVGVEHEHLVECARKYLLGAQPAWGATGAVDVDRSVAQYTGGIVKVERDMSNVSLGPTPIPELTHIMVGLESCSFLEDDFIPFAVLNMMMGGGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGRTVDLVELERAKTQLMSMLMMNLESRPVIFEDVGRQVLATHSRKLPHELCTLIRNVKPEDIKRVASKMLRGKPAVAALGDLTDLPTYDHIQAALASRDGRLPRTYRLFR", "length": 425, "header": "tr|A0A9J7JW74-1|A0A8C2QE55_CRIGR Computationally mapped isoform of Mitochondrial-processing peptidase subunit alpha OS=Cricetulus griseus OX=10029 GN=Pmpca PE=3 SV=1 CANONICAL=A0A8C2QE55-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 311, "start_aa": "Thr", "end_pos": 311, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr311", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JW74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW74" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JW74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW74" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761595", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761595", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE55", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE55", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE55", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE55", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE55", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein processing involved in protein targeting to mitochondrion", "id": "GO:0006627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006627", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE55", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QE55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE55" }, { "id": "PF05193", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05193" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M16 C-terminal", "eco_id": "ECO_0000259", "start_pos": 231, "end_pos": 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Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027257889", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257889" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE63", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE63" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fam184a", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE63", "locus": {} } ], "crossref": [ { "id": "100767811", "url": "https://www.ncbi.nlm.nih.gov/gene/100767811", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767811", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767811", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QE63", "url": "https://www.orthodb.org/?gene=A0A8C2QE63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18870", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18870", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18870:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18870:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027257889", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257889", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QE63", "url": 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"length": 1143, "header": "tr|A0A8C2QE63-1|A0A8C2QE63_CRIGR Isoform 1 of Protein FAM184A isoform X2 OS=Cricetulus griseus OX=10029 GN=Fam184a PE=4 SV=1 CANONICAL=A0A8C2QE63-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QE63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE63/entry#A0A8C2QE63-1", "sequence": { "sequence": 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"length": 1143, "header": "tr|A0A8C2QE63-1|A0A8C2QE63_CRIGR Isoform 1 of Protein FAM184A isoform X2 OS=Cricetulus griseus OX=10029 GN=Fam184a PE=4 SV=1 CANONICAL=A0A8C2QE63-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GQQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE63/entry#A0A9J7GQQ3-1", "sequence": { "sequence": "MKQQALTEFEAYKHRVEDMQLCAEAQHVQRIVTMSREVEEIRRKFEERLQSFGQLQVQFEKDKQLALEELRTTHRREVQELLKSQQDHSASVNQGQEKMEQLHRMEVEALNSTLEELRLEKKKLIEEYEGKLSKAQSFYERELDNMKRSQLFTAESLQASRDKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEASSLLDKCQKLQGALATAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAAQERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKCRANERLCQLEKERAFLQSRTRSLDEEQKQQLLELEKRVNEAKRTQQEYYEMELKTLQNRLEGEVAQLNEAHSKTLKELAWKHHMAMEAVHNNASRDKKKLQMELEEQYKKEKLSLEEDKSQLQLELENLKQVLEDKLTSANQEIGRLQDLVRKSEQDLGSAEGLIASLQDSQEKLQSELDLTKGRLKDTKDVLLKVEAELQQERHQHEETLAAMKEEEKLRVGRMAHDLEIKWTENLRLECSKLRQELRLQHEEDKKSAMSQLLQLKEREKNAARDSWQKKVEDLLNQISLLKQNLELQLCQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRMEMEQELQTLRFELEDEGKAMLASLRSELNHQHAASIDLLRHNHHQELAAAKMELERSIDISRRQSKEHMCRISDLQEELRHREHHISDLDKEVQHLHENISTLTKELELKGKEILRIRSDSNQQMRLEEMEEKYLMRESKPEDIQMIAELKSLLSERDRVIKKLIQKKKNDKSPSNRFVSVPNLSALESCGVGNGHPTRLEPIPNSPIHDVEFNSNKPLPQPLPPKEPKTFLSPPQSEASPVASPDPQRQEWFARYFTF", "length": 936, "header": "tr|A0A9J7GQQ3-1|A0A9J7GQQ3_CRIGR Computationally mapped isoform of Protein FAM184A isoform X4 OS=Cricetulus griseus OX=10029 GN=Fam184a PE=4 SV=1 CANONICAL=A0A8C2QE63-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K470-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE63/entry#A0A9J7K470-1", "sequence": { "sequence": "MKQQALTEFEAYKHRVEDMQLCAEAQHVQRIVTMSREVEEIRRKFEERLQSFGQLQVQFEKDKQLALEELRTTHRREVQELLKSQQDHSASVNQGQEKMEQLHRMEVEALNSTLEELRLEKKKLIEEYEGKLSKAQSFYERELDNMKRSQLFTAESLQASRDKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEASSLLDKCQKLQGALATAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAAQERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKCRANERLCQLEKERAFLQSRTRSLDEEQKQQLLELEKRVNEAKRTQQEYYEMELKTLQNRLEGEVAQLNEAHSKTLKELAWKHHMAMEAVHNNASRDKKKLQMELEEQYKKEKLSLEEDKSQLQLELENLKQVLEDKLTSANQEIGRLQDLVRKSEQDLGSAEGLIASLQDSQEKLQSELDLTKGRLKDTKDVLLKVEAELQQERHQHEETLAAMKEEEKLRVGRMAHDLEIKWTENLRLECSKLRQELRLQHEEDKKSAMSQLLQLKEREKNAARDSWQKKVEDLLNQISLLKQNLELQLCQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRMEMEQELQTLRFELEDEGKAMLASLRSELNHQHAASIDLLRHNHHQELAAAKMELERSIDISRRQSKEHMCRISDLQEELRHREHHISDLDKEVQHLHENISTLTKELELKGKEILRIRSDSNQQMRLEEMEEKYLMRESKPEDIQMIAELKSLLSERDRVIKKLIEDNKFYQLELVNRETNFNKIFNTSPTVGVINPLAKQKKKNDKSPSNRFVSVPNLSALESCGVGNGHPTRLEPIPNSPIHDVEFNSNKPLPQPLPPKEPKTFLSPPQSEASPVASPDPQRQEWFARYFTF", "length": 971, "header": "tr|A0A9J7K470-1|A0A8C2QE63_CRIGR Computationally mapped isoform of Protein FAM184A isoform X2 OS=Cricetulus griseus OX=10029 GN=Fam184a PE=4 SV=1 CANONICAL=A0A8C2QE63-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1040, "start_aa": "Thr", "end_pos": 1040, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1040", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3, "start_aa": "Thr", "end_pos": 3, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K470", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K470" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K470", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K470" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767811", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767811", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE63", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE63" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE63", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE63" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE63", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE63" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE63", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE63" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1036, "end_pos": 1038, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1067, "end_pos": 1069, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 503, "end_pos": 505, "annotation": "n_glycosylation_sequon" }, { "start_pos": 899, "end_pos": 901, "annotation": "n_glycosylation_sequon" }, { 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}, { "name": "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_007640801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640801" } ] }, { "name": "HIBADH", "type": "synonym", "evidence": [ { "id": "A0A8C2QE64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE64/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613870.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007640801", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640801" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE64", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE64" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Hibadh", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE64", "locus": {} } ], "crossref": [ { "id": "100760581", "url": "https://www.ncbi.nlm.nih.gov/gene/100760581", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006115", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006115", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008927", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008927", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760581", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760581", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MGKKVWH", "url": "https://omabrowser.org/oma/group/MGKKVWH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QE64", "url": "https://www.orthodb.org/?gene=A0A8C2QE64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22981", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22981", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22981:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22981:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03446", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03446", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007640801", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640801", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17681", "url": "https://www.rhea-db.org/rhea/17681", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QE64", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QE64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASLGLRGAASGLRYWSGRPRPAASLAAVCSRSMASKTPVGFIGLGNMGNPMAKNLMKHGYPLILYDVFPDACKEFQEAGEQVASSPADVAEKADRIITMLPTSMNSVEVYSGANGILQKVKKGSLLIDSSTIDPSVSKQLAKEVEKMGAVFMDAPVSGGVGAAQSGNLTFMVGGVEDEFAAAQELLGCMGSNVIYCGAVGTGQAAKICNNMLLAISMIGTAEAMNLGIRSGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMDGVPSSNNYQGGFGTTLMAKDLGLAQDSATSTKSPILLGSLAHQIYRMMCAKGYSTKDFSSVFQYLREEETF", "length": 335, "header": "tr|A0A8C2QE64-1|A0A8C2QE64_CRIGR Isoform 1 of 3-hydroxyisobutyrate dehydrogenase OS=Cricetulus griseus OX=10029 GN=Hibadh PE=3 SV=1 CANONICAL=A0A8C2QE64-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QE64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE64/entry#A0A8C2QE64-1", "sequence": { "sequence": "MAASLGLRGAASGLRYWSGRPRPAASLAAVCSRSMASKTPVGFIGLGNMGNPMAKNLMKHGYPLILYDVFPDACKEFQEAGEQVASSPADVAEKADRIITMLPTSMNSVEVYSGANGILQKVKKGSLLIDSSTIDPSVSKQLAKEVEKMGAVFMDAPVSGGVGAAQSGNLTFMVGGVEDEFAAAQELLGCMGSNVIYCGAVGTGQAAKICNNMLLAISMIGTAEAMNLGIRSGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMDGVPSSNNYQGGFGTTLMAKDLGLAQDSATSTKSPILLGSLAHQIYRMMCAKGYSTKDFSSVFQYLREEETF", "length": 335, "header": "tr|A0A8C2QE64-1|A0A8C2QE64_CRIGR Isoform 1 of 3-hydroxyisobutyrate dehydrogenase OS=Cricetulus griseus OX=10029 GN=Hibadh PE=3 SV=1 CANONICAL=A0A8C2QE64-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE64", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE64" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE64", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE64" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760581", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760581", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PH80-1", "protein_name": "3-hydroxyisobutyrate dehydrogenase", "gene_name": "HIBADH", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAVVLGGPAGWWRWHRRVRAARAAMVCSRAMASKTPVGFIGLGNMGNPMAKNLIKHGYPVIAYDVFPEACKEFQDLGAQVTDSPADVAERADRIITMLPSSPNAIEVYTGANGILKKVKKGSLLIDSSTIDPSVSKELAKAVEKMGAVFMDAPVSGGVGAARAGNLTFMVGGMEQEFDAAKELLICMGSNVVYCGEVGTGQAAKICNNMLLAISMIGTAETMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMEGVPSANNYQGGFGTTLMAKDLGLAQISATNTKTPVPLGSQAHQIYRMMCAKGYALKDFSAVFQFLPHLRNMWV", "length": 335 }, "evidence": [ { "id": "A0A8C2QE64", "url": "https://omabrowser.org/oma/group/A0A8C2QE64/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SHU0-1", "protein_name": "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "gene_name": "HIBADH", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAASLRLRGAASGLLYWSRRQRPAAASLVAVCSRSMASKTPVGFIGVGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFLDAGEQVVSSPADVAEKADRIITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPMISKELAKEVEKMGAVFMDAPVSGGVGAARSGNLTFMVGGVEEEFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNLLLAISMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMDGVPSANNYQGGFGTTLMAKDLGLAQDSATSTKSPILLGSQAHQIYRLMCAKGYANKDFSSVFQFLREEETF", "length": 336 }, "evidence": [ { "id": "A0A8C2QE64", "url": "https://omabrowser.org/oma/group/A0A8C2QE64/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P29266-1", "protein_name": "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "gene_name": "Hibadh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASLGFRGAASGLRYWSGRRRPVGSLAAVCSRSMASKTPVGFIGLGNMGNPMAKNLIKHGYPLILYDVFPDVCKEFKEAGEQVASSPADVAEKADRIITMLPSSMNSIEVYSGANGILKKVKKGSLLIDSSTIDPSVSKELAKEVEKMGAVFMDAPVSGGVGAARSGNLTFMVGGVENEFAAAQELLGCMGSNVLYCGAVGSGQSAKICNNMLLAISMIGTAEAMNLGIRSGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMDGVPSSNNYQGGFGTTLMAKDLGLAQDSATSTKTPILLGSVAHQIYRMMCSKGYSKKDFSSVFQYLREEETF", "length": 335 }, "evidence": [ { "id": "A0A8C2QE64", "url": "https://omabrowser.org/oma/group/A0A8C2QE64/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P31937-1", "protein_name": "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "gene_name": "HIBADH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASLRLLGAASGLRYWSRRLRPAAGSFAAVCSRSVASKTPVGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSSPADVAEKADRIITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNMLLAISMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMDGVPSANNYQGGFGTTLMAKDLGLAQDSATSTKSPILLGSLAHQIYRMMCAKGYSKKDFSSVFQFLREEETF", "length": 336 }, "evidence": [ { "id": "A0A8C2QE64", "url": "https://omabrowser.org/oma/group/A0A8C2QE64/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2HJD7-1", "protein_name": "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "gene_name": "HIBADH", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAASLRLRGAASGLRYWSRRQPPAVASLAAVCSRSMASKTPVGFIGVGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFLDAGEQVVSSPADVAEKADRIITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPMVSKELAKEVEKMGAVFMDAPVSGGVGAARSGNLTFMVGGVEEEFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNLLLAISMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMDGVPSANNYQGGFGTTLMAKDLGLAQDSATSTKSPILLGSQAHQIYRMMCAKGYSKKDFSSVFQFLREEETF", "length": 336 }, "evidence": [ { "id": "A0A8C2QE64", "url": "https://omabrowser.org/oma/group/A0A8C2QE64/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54CX6-1", "protein_name": "Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial", "gene_name": "hibA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSSKKSLLLFKNVRYMSTSSSKTVGFIGLGNMGGHQAINLIKKGHNLIVFDMSKDNMNRLKEKGAKIANSPAEVAKEADVIVTMLPASAHVKNVYCGENGIFQTVRPGTLLLDSSTIDPATAREVASIAKKHQSTMLDCPVSGGTGGAEAGTLTFMVGGSEQDFNTAKTYLECMGKNIVHCGDVGTGQVAKVCNNLVLGISMIAVSEAMNLGVKQGMDPKKLAGIFNTSSARCWTSELYNPCPGVIETSPASRGYTGGFGSALMTKDLGLAVDSAKSIGEPLLLGNSAHQLYTLLVAKGDGQKDFSVVYDFLNKNFKNSN", "length": 321 }, "evidence": [ { "id": "A0A8C2QE64", "url": "https://omabrowser.org/oma/group/A0A8C2QE64/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q99L13-1", "protein_name": "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "gene_name": "Hibadh", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASLGFRGAASGLWYWSGRRRPVGSLAAVCSRSMASKTPVGFIGLGNMGNPMAKNLMKHGYPLILYDVFPDVCKEFKEAGEQVASSPAEVAEKADRIITMLPSSMNAVEVYSGANGILKKVKKGSLLIDSSTIDPSVSKELAKEVEKMGAVFMDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLECMGSNVVYCGAVGTGQSAKICNNMLLAISMIGTAEAMNLGIRSGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMHGVPSSNNYQGGFGTTLMAKDLGLAQDSATSTKTPILLGSLAHQIYRMMCSKGYSKKDFSSVFQYLREEEPF", "length": 335 }, "evidence": [ { "id": "A0A8C2QE64", "url": "https://omabrowser.org/oma/group/A0A8C2QE64/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SUC0-1", "protein_name": "Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAIRRAQTLLCLSKFKTNFVSGSLHRFSSSSQNSNQFQNVGFIGLGNMGFRMVNNLIRAGYKVTVHDINRDVMKMFTEMGVSSRETPYEVAQDSEVVITMLPSSSHVMDVYTGTNGLLLGENDIRPALFIDSSTIDPQTTRKISLAVSNCNLKEKRDNWEKPVMLDAPVSGGVLAAEAGTLTFMVGGPEDAYLAARPILQSMGRTSIYCGGSGNGSAAKICNNLAMAVSMLGTSEALALGQSLGISASTLTEVLNTSSGRCWSSDAYNPVPGVMKGVPSSRDYNGGFASKLMAKDLNLAAASAEEVGHKSPLISKAQEIYKKMCEEGHETKDFSCVFRHFYNGKDEV", "length": 347 }, "evidence": [ { "id": "A0A8C2QE64", "url": "https://omabrowser.org/oma/group/A0A8C2QE64/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9V8M5-1", "protein_name": "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "gene_name": "Hibadh", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17681", "name": "", "equation": "3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8C2QE64-1" ], "evidence": [ { "id": "17681", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17681" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8C2QE64", "gene_name": "Hibadh", "activity": [ { "ec_number": "1.1.1.31", "activity": "3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH + H(+).", "evidence": [ { "id": "A0A8C2QE64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE64" } ] }, { 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"title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QE95-1", "uniprot_ac": "A0A8C2QE95", "uniprot_id": "A0A8C2QE95_CRIGR", "mass": { "chemical_mass": 16320.0, "monoisotopic_mass": 16320.0 }, "refseq": { "ac": "XP_003502916", "name": "actin-related protein 2/3 complex subunit 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502916" }, "gene_names": [ { "name": "Arpc5", "type": "recommended", "evidence": [ { "id": "A0A8C2QE95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE95" } ] }, { "name": "Arpc5", "type": "synonym", "evidence": [ { "id": "XP_003502916", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502916" } ] } ], "protein_names": [ { "name": "Actin-related protein 2/3 complex subunit 5", "type": "recommended", "evidence": [ { "id": "A0A8C2QE95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE95/entry#names_and_taxonomy" } ] }, { "name": "actin-related protein 2/3 complex subunit 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003502916", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502916" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 394 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613921.1) and transcript sequence (IACG01090005.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003502916.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502916", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502916" } ] }, { "annotation": "Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE95", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE95#function" }, { "database": "UniProtKB", "id": "RU004301", "url": "https://www.uniprot.org/uniprotkb/RU004301#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE95", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE95" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Arpc5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE95", "locus": {} } ], "crossref": [ { "id": "100766799", "url": "https://www.ncbi.nlm.nih.gov/gene/100766799", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766799", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766799", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QE95", "url": "https://www.orthodb.org/?gene=A0A8C2QE95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12644", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12644", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502916", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502916", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QE95", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QE95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKNTVSSARFRKVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLRQGNMTAALQAALKNPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNGVDLLMKYIYKGFESPSDNSSAMLLQWHEKALAAGGVGSIVRVLTARKTV", "length": 151, "header": "tr|A0A8C2QE95-1|A0A8C2QE95_CRIGR Isoform 1 of Actin-related protein 2/3 complex subunit 5 OS=Cricetulus griseus OX=10029 GN=Arpc5 PE=3 SV=1 CANONICAL=A0A8C2QE95-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QE95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE95/entry#A0A8C2QE95-1", "sequence": { "sequence": "MSKNTVSSARFRKVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLRQGNMTAALQAALKNPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNGVDLLMKYIYKGFESPSDNSSAMLLQWHEKALAAGGVGSIVRVLTARKTV", "length": 151, "header": "tr|A0A8C2QE95-1|A0A8C2QE95_CRIGR Isoform 1 of Actin-related protein 2/3 complex subunit 5 OS=Cricetulus griseus OX=10029 GN=Arpc5 PE=3 SV=1 CANONICAL=A0A8C2QE95-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QE95", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QE95" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FNEMTQP", "url": "https://omabrowser.org/oma/group/FNEMTQP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QEE7", "url": "https://www.orthodb.org/?gene=A0A8C2QEE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15494", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15494", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027250198", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250198", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QEE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QEE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPEIVEVEPEANIRGAEIVTMGENDPPAAEAPFSFRSLFGLDDLKISPVAPDADAVAAQILSLLPLKFFPIIVIGIIALILALAIGLGIHFDCSGKYRCHSSFKCIELTARCDGVSDCKDGEDEYRCVRVSGQRAALQVFTAAAWRTMCSDDWKSHYAKVACAQLGFPSYVSSDHLRVDALEEQFQGDFVSINHLLPDDKVTTLHHSVYMREGCASGHVVTLKCLACGLRPGYSFRIVGGNMSSLAQWPWQVSLQFQGYHLCGGSVITPLWIVTAAHCVYDLYHPKSWTVQVGLVSLMDSPVPSHLVEKIIYHSKYKPKRLGNDIALMKLAEPLSFDGTIQPVCLPNSEENFPDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQLERDLKT", "length": 475, "header": "tr|A0A8C2QEE7-1|A0A8C2QEE7_CRIGR Isoform 1 of Transmembrane protease serine 3 OS=Cricetulus griseus OX=10029 GN=Tmprss3 PE=4 SV=1 CANONICAL=A0A8C2QEE7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QEE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEE7/entry#A0A8C2QEE7-1", "sequence": { "sequence": "MAAPEIVEVEPEANIRGAEIVTMGENDPPAAEAPFSFRSLFGLDDLKISPVAPDADAVAAQILSLLPLKFFPIIVIGIIALILALAIGLGIHFDCSGKYRCHSSFKCIELTARCDGVSDCKDGEDEYRCVRVSGQRAALQVFTAAAWRTMCSDDWKSHYAKVACAQLGFPSYVSSDHLRVDALEEQFQGDFVSINHLLPDDKVTTLHHSVYMREGCASGHVVTLKCLACGLRPGYSFRIVGGNMSSLAQWPWQVSLQFQGYHLCGGSVITPLWIVTAAHCVYDLYHPKSWTVQVGLVSLMDSPVPSHLVEKIIYHSKYKPKRLGNDIALMKLAEPLSFDGTIQPVCLPNSEENFPDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQLERDLKT", "length": 475, "header": "tr|A0A8C2QEE7-1|A0A8C2QEE7_CRIGR Isoform 1 of Transmembrane protease serine 3 OS=Cricetulus griseus OX=10029 GN=Tmprss3 PE=4 SV=1 CANONICAL=A0A8C2QEE7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEE7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEE7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760202", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760202", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZY65-1", "protein_name": "Transmembrane protease serine 3", "gene_name": "Tmprss3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPETVEVEPEPNIRGPEIVTMGENDPPAAEAPFSFRSLFGLDDLKISSVAPDGDAVAAQILSLLPLKFFPIIVIGIIALILALAIGLGIHFDCSGKYRCHSSFKCIELTARCDGVPNCKDGEDEYRCVRVSGQRAALQVFTAAAWRTMCSDDWKSHYAKIACAQLGFPSYVSSDHLRVDALEEQFQGDFVSINHLLPDDKVTALHHSVYMREGCTSGHVVTLKCSACGMRTGYSPRIVGGNVSSLTQWPWQVSLQFQGYHLCGGSVITPLWIVTAAHCVYDLYHPKSWTVQVGLVSLMDSPVPSHLVEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETIQPICLPNSEENFPDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLERDLKT", "length": 475 }, "evidence": [ { "id": "A0A8C2QEE7", "url": "https://omabrowser.org/oma/group/A0A8C2QEE7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P57727-1", "protein_name": "Transmembrane protease serine 3", "gene_name": "TMPRSS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGENDPPAVEAPFSFRSLFGLDDLKISPVAPDADAVAAQILSLLPLKFFPIIVIGIIALILALAIGLGIHFDCSGKYRCRSSFKCIELIARCDGVSDCKDGEDEYRCVRVGGQNAVLQVFTAASWKTMCSDDWKGHYANVACAQLGFPSYVSSDNLRVSSLEGQFREEFVSIDHLLPDDKVTALHHSVYVREGCASGHVVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVGLVSLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQMERDLKT", "length": 454 }, "evidence": [ { "id": "A0A8C2QEE7", "url": "https://omabrowser.org/oma/group/A0A8C2QEE7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K1T0-1", "protein_name": "Transmembrane protease serine 3", "gene_name": "Tmprss3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGENDPPAAEAPFSFRSLFGLDDLKISPVAPDGDAVAAQILSLLPLKFFPIIVIGIIALILALAIGLGIHFDCSGKYRCHSSFKCIELTARCDGVSDCKNAEDEYRCVRVSGQRAALQVFTAAAWRTMCSDDWKSHYAKIACAQLGFPSYVSSDHLRVDALEEQFQGDFVSINHLLSDDKVTALHHSVYMREGCTSGHVVTLKCSACGTRTGYSPRIVGGNMSSLTQWPWQVSLQFQGYHLCGGSIITPLWIVTAAHCVYDLYHPKSWTVQVGLVSLMDSPVPSHLVEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETIQPICLPNSEENFPDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLERDLKT", "length": 453 }, "evidence": [ { "id": "A0A8C2QEE7", "url": "https://omabrowser.org/oma/group/A0A8C2QEE7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEE7" } ], "pmid": "" }, { "name": "sodium channel regulator activity", "id": "GO:0017080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017080", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEE7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEE7" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEE7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEE7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEE7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QEE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEE7" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 239, "end_pos": 470, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2QEE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEE7" }, { "id": "PS50287", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50287" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SRCR", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 169, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 243, "end_pos": 245 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QEG5-1", "uniprot_ac": "A0A8C2QEG5", "uniprot_id": "A0A8C2QEG5_CRIGR", "mass": { "chemical_mass": 27858.0, "monoisotopic_mass": 27858.0 }, "refseq": { "ac": "XP_007641186", "name": "RNA-binding protein PNO1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641186" }, "gene_names": [ { "name": "Pno1", "type": "recommended", "evidence": [ { "id": "A0A8C2QEG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEG5" } ] }, { "name": "Pno1", "type": "synonym", "evidence": [ { "id": "XP_007641186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641186" } ] } ], "protein_names": [ { "name": "RNA-binding protein PNO1", "type": "recommended", "evidence": [ { "id": "A0A8C2QEG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEG5/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein PNO1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007641186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641186" } ] }, { "name": "RNA-binding protein pno1", "type": "synonym", "evidence": [ { "id": "A0A8C2QEG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEG5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 58 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613893.1) and transcript sequence (IACG01060172.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007641186", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641186" } ] }, { "annotation": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEG5#function" }, { "database": "UniProtKB", "id": "ARBA00053193", "url": "https://www.uniprot.org/uniprotkb/ARBA00053193#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEG5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pno1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEG5", "locus": {} } ], "crossref": [ { "id": "cd22391", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22391", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22392", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22392", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100750394", "url": "https://www.ncbi.nlm.nih.gov/gene/100750394", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750394", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750394", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QEG5", "url": "https://www.orthodb.org/?gene=A0A8C2QEG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12826", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12826", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12826:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12826:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22891", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22891", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007641186", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641186", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QEG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEMETQNTGAEDGFTPVTHRGGRRAKKRQAEQLSAAGQDGDASRMDTEEALPAKRPIFPPLSGERLLTGKEETRKIPVPANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTCKDTKDVSSLTKAADFVKAFVLGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF", "length": 251, "header": "tr|A0A8C2QEG5-1|A0A8C2QEG5_CRIGR Isoform 1 of RNA-binding protein PNO1 OS=Cricetulus griseus OX=10029 GN=Pno1 PE=3 SV=1 CANONICAL=A0A8C2QEG5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QEG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEG5/entry#A0A8C2QEG5-1", "sequence": { "sequence": "MAEMETQNTGAEDGFTPVTHRGGRRAKKRQAEQLSAAGQDGDASRMDTEEALPAKRPIFPPLSGERLLTGKEETRKIPVPANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTCKDTKDVSSLTKAADFVKAFVLGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF", "length": 251, "header": "tr|A0A8C2QEG5-1|A0A8C2QEG5_CRIGR Isoform 1 of RNA-binding protein PNO1 OS=Cricetulus griseus OX=10029 GN=Pno1 PE=3 SV=1 CANONICAL=A0A8C2QEG5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"database": "UniProtKB", "id": "A0A8C2QEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QEG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEG5" }, { "id": "SM00322", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "K Homology", "eco_id": "ECO_0000259", "start_pos": 156, "end_pos": 229, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306238" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC103159465", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH0", "locus": {} } ], "crossref": [ { "id": "103159465", "url": "https://www.ncbi.nlm.nih.gov/gene/103159465", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103159465", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103159465", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RYKFEAW", "url": "https://omabrowser.org/oma/group/RYKFEAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QEH0", "url": "https://www.orthodb.org/?gene=A0A8C2QEH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23310", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23310", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23310:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23310:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00887", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00887", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306238", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QEH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QEH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQAEFDKAAEEVKHLKTQPSDKEMLFIYSHSKQASVGDVNTDWPGLLDLKGKAKWDSWNKLKGTSKESAMKTYVEKVEELKKYRI", "length": 86, "header": "tr|A0A8C2QEH0-1|A0A8C2QEH0_CRIGR Isoform 1 of Acyl-CoA-binding protein OS=Cricetulus griseus OX=10029 GN=LOC103159465 PE=4 SV=1 CANONICAL=A0A8C2QEH0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QEH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH0/entry#A0A8C2QEH0-1", "sequence": { "sequence": "MSQAEFDKAAEEVKHLKTQPSDKEMLFIYSHSKQASVGDVNTDWPGLLDLKGKAKWDSWNKLKGTSKESAMKTYVEKVEELKKYRI", "length": 86, "header": "tr|A0A8C2QEH0-1|A0A8C2QEH0_CRIGR Isoform 1 of Acyl-CoA-binding protein OS=Cricetulus griseus OX=10029 GN=LOC103159465 PE=4 SV=1 CANONICAL=A0A8C2QEH0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103159465", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103159465", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZVX8-1", "protein_name": "Acyl-CoA-binding protein", "gene_name": "LOC102553848", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "IASQAEFDKAAEEVKCLKSQPTEEEMLLLYSHFKQATVGDVNTDRPGLLDLKGKAKWDALNELKGTSKKNTMKTYVEKAEELKKKYGI", "length": 88 }, "evidence": [ { "id": "A0A8C2QEH0", "url": "https://omabrowser.org/oma/group/A0A8C2QEH0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZFV1-1", "protein_name": "Acyl-CoA-binding protein", "gene_name": "DBI", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSEAAFQKAAEEVKQLKSQPTDQEMLDVYSHYKQATVGDVNTDRPGMLDFKGKAKWDAWNALKGMSKEDAMKAYVAKVEELKGKYGI", "length": 87 }, "evidence": [ { "id": "A0A8C2QEH0", "url": "https://omabrowser.org/oma/group/A0A8C2QEH0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P07108-1", "protein_name": "Acyl-CoA-binding protein", "gene_name": "DBI", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQAEFEKAAEEVRHLKTKPSDEEMLFIYGHYKQATVGDINTERPGMLDFTGKAKWDAWNELKGTSKEDAMKAYINKVEELKKKYGI", "length": 87 }, "evidence": [ { "id": "A0A8C2QEH0", "url": "https://omabrowser.org/oma/group/A0A8C2QEH0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P12026-1", "protein_name": "Acyl-CoA-binding protein", "gene_name": "DBI", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSQAEFEKAAEEVKNLKTKPADDEMLFIYSHYKQATVGDINTERPGILDLKGKAKWDAWNGLKGTSKEDAMKAYINKVEELKKKYGI", "length": 87 }, "evidence": [ { "id": "A0A8C2QEH0", "url": "https://omabrowser.org/oma/group/A0A8C2QEH0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P31787-1", "protein_name": "Acyl-CoA-binding protein", "gene_name": "ACB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVSQLFEEKAKAVNELPTKPSTDELLELYALYKQATVGDNDKEKPGIFNMKDRYKWEAWENLKGKSQEDAEKEYIALVDQLIAKYSS", "length": 87 }, "evidence": [ { "id": "A0A8C2QEH0", "url": "https://omabrowser.org/oma/group/A0A8C2QEH0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P57752-1", "protein_name": "Acyl-CoA-binding domain-containing protein 6", "gene_name": "ACBP6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGLKEEFEEHAEKVNTLTELPSNEDLLILYGLYKQAKFGPVDTSRPGMFSMKERAKWDAWKAVEGKSSEEAMNDYITKVKQLLEVAASKAST", "length": 92 }, "evidence": [ { "id": "A0A8C2QEH0", "url": "https://omabrowser.org/oma/group/A0A8C2QEH0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q5FXM5-1", "protein_name": "Acyl-CoA-binding protein", "gene_name": "acbA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTFEEAAQKVKEFTKKPSNDELLSLYGLYKQGTDGDCNISEPWAVQVEAKAKYNAWNALKGTSKEDAKAKYVALYEQLATKYA", "length": 84 }, "evidence": [ { "id": "A0A8C2QEH0", "url": "https://omabrowser.org/oma/group/A0A8C2QEH0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH0" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "fatty-acyl-CoA binding", "id": "GO:0000062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000062", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEH0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2QEH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH0" }, { "id": "PS51228", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51228" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ACB", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 86, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QEH9-1", "uniprot_ac": "A0A8C2QEH9", "uniprot_id": "A0A8C2QEH9_CRIGR", "mass": { "chemical_mass": 72848.0, "monoisotopic_mass": 72848.0 }, "refseq": { "ac": "XP_027260258", "name": "mini-chromosome maintenance complex-binding protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260258" }, "gene_names": [ { "name": "Mcmbp", "type": "recommended", "evidence": [ { "id": "A0A8C2QEH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH9" } ] }, { "name": "Mcmbp", "type": "synonym", "evidence": [ { "id": "XP_027260258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260258" } ] } ], "protein_names": [ { "name": "Mini-chromosome maintenance complex-binding protein", "type": "recommended", "evidence": [ { "id": "A0A8C2QEH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH9/entry#names_and_taxonomy" } ] }, { "name": "mini-chromosome maintenance complex-binding protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027260258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260258" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260258", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260258" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEH9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mcmbp", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH9", "locus": {} } ], "crossref": [ { "id": "100754052", "url": "https://www.ncbi.nlm.nih.gov/gene/100754052", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754052", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754052", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QEH9", "url": "https://www.orthodb.org/?gene=A0A8C2QEH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13489:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13489:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09739", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09739", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027260258", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260258", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QEH9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QEH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GTG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GTG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JH95", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JH95-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPCGEDWLSHPLGIVQGFFAQNGVNPDWEKKVIEYFKEKLKENNAPKWVPSLNEVPLHYLKPNSFVKFRCMIQDMFDPEFYMGVYETVNQTTKARVLHFGKYRDVAECGPQQELDLSSPRSTTAERQTFYCVPVPGESSWVKEAYVNANQARVSPSTSYTPSRHKRSYEDDEDMDLQPNKQKDQHAGAQQAGGLGGLHWCGEPKRLETEASSGQQLSSLNLSSPFDLNFPLPGEKGPACLVKVYEDWDCFKVNDVLELYGVLSVDPVLSILNNEEREASALLDPMECTDMAEEQRVHSPPASLVPRIHVILAQKLQHINPLLPTCLNKEESRTCKFVSSFMSELSPVRAELLGFLTHALLGDSLAAEYLILHLISTVYTRRDVLPLGKFTVNLSGCPQNSTFTEHLYRIIQHLVPASFRLQMTIENMNQLKFIPHKDYTANRLVSGLLQLPNNTSLVIDETLLEQGQLDTSGVHNVTALSNLITWQKVDYDFSYHQMEFPCSINVLVTSEGRSLLPADCQIHLQPQLIPPNMEEYMNSLLSTVLPSVLNKFRIYLTLLRFLDYNISDDITKAVEDDFVEMRKNDPQSITADDLHQLLVVARFLSLSAGQTTLSRERWLRAKQLESSRKNRLQQHKCVNGNEL", "length": 642, "header": "tr|A0A8C2QEH9-1|A0A8C2QEH9_CRIGR Isoform 1 of Mini-chromosome maintenance complex-binding protein OS=Cricetulus griseus OX=10029 GN=Mcmbp PE=3 SV=1 CANONICAL=A0A8C2QEH9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QEH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH9/entry#A0A8C2QEH9-1", "sequence": { "sequence": "MPCGEDWLSHPLGIVQGFFAQNGVNPDWEKKVIEYFKEKLKENNAPKWVPSLNEVPLHYLKPNSFVKFRCMIQDMFDPEFYMGVYETVNQTTKARVLHFGKYRDVAECGPQQELDLSSPRSTTAERQTFYCVPVPGESSWVKEAYVNANQARVSPSTSYTPSRHKRSYEDDEDMDLQPNKQKDQHAGAQQAGGLGGLHWCGEPKRLETEASSGQQLSSLNLSSPFDLNFPLPGEKGPACLVKVYEDWDCFKVNDVLELYGVLSVDPVLSILNNEEREASALLDPMECTDMAEEQRVHSPPASLVPRIHVILAQKLQHINPLLPTCLNKEESRTCKFVSSFMSELSPVRAELLGFLTHALLGDSLAAEYLILHLISTVYTRRDVLPLGKFTVNLSGCPQNSTFTEHLYRIIQHLVPASFRLQMTIENMNQLKFIPHKDYTANRLVSGLLQLPNNTSLVIDETLLEQGQLDTSGVHNVTALSNLITWQKVDYDFSYHQMEFPCSINVLVTSEGRSLLPADCQIHLQPQLIPPNMEEYMNSLLSTVLPSVLNKFRIYLTLLRFLDYNISDDITKAVEDDFVEMRKNDPQSITADDLHQLLVVARFLSLSAGQTTLSRERWLRAKQLESSRKNRLQQHKCVNGNEL", "length": 642, "header": "tr|A0A8C2QEH9-1|A0A8C2QEH9_CRIGR Isoform 1 of Mini-chromosome maintenance complex-binding protein OS=Cricetulus griseus OX=10029 GN=Mcmbp PE=3 SV=1 CANONICAL=A0A8C2QEH9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GTG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH9/entry#A0A9J7GTG6-1", "sequence": { "sequence": "MPCGEDWLSHPLGIVQGFFAQNGVNPDWEKKVIEYFKEKLKENNAPKWVPSLNEVPLHYLKPNSFVKFRCMIQDMFDPEFYMGVYETVNQTTKARVLHFGKYRDVAECGPQQELDLSSPRSTTAERQTFYCVPVPGESSWVKEAYVNANQARVSPSTSYTPSRHKRSYEDDEDMDLQPNKQKDQHAGAQQAGGLGGLHWCGEPKRLETEASSGQQLSSLNLSSPFDLNFPLPGEKGPACLVKVYEDWDCFKVNDVLELYGVLSVDPVLSILNNEEREASALLDPMECTDMAEEQRVHSPPASLVPRIHVILAQKLQHINPLLPTCLNKEESRTCKFVSSFMSELSPVRAELLGFLTHALLGDSLAAEYLILHLISTVYTRRDVLPLGKFTVNLSGCPQNSTFTEHLYRIIQHLVPASFRLQMTIENMNQLKFIPHKDYTANRLVSGLLQLPNNTSLVIDETLLEQGQLDTSGVHNVTALSNLITWQKVDYDFSYHQMEFPCSINVLVTSEGRSLLPADCQIHLQPQLIPPNMEEYMNSLLSTVLPSVLNKFRIYLTLLRFLDYNISDDITKAVEDDFVEMRKNDPQSITADDLHQLLVVARFPHGSPLWKRTHEGNPPDSAIST", "length": 624, "header": "tr|A0A9J7GTG6-1|A0A9J7GTG6_CRIGR Computationally mapped isoform of Mini-chromosome maintenance complex-binding protein OS=Cricetulus griseus OX=10029 GN=Mcmbp PE=3 SV=1 CANONICAL=A0A8C2QEH9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JH95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH9/entry#A0A9J7JH95-1", "sequence": { "sequence": "MPCGEDWLSHPLGIVQGFFAQNGVNPDWEKKVIEYFKEKLKENNAPKWVPSLNEVPLHYLKPNSFVKFRCMIQDMFDPEFYMGVYETVNQTTKARVLHFGKYRDVAECGPQQELDLSSPRSTTAERQTFYCVPVPGESSWVKEAYVNANQARVSPSTSYTPSRHKRSYEDDEDMDLQPNKQKDQHAGAQQAGGLGGLHWCGEPKRLETEASSGQQLSSLNLSSPFDLNFPLPGEKGPACLVKVYEDWDCFKVNDVLELYGVLSVDPVLSILNNEEREASALLDPMECTDMAEEQRVHSPPASLVPRIHVILAQKLQHINPLLPTCLNKEESRTFVSSFMSELSPVRAELLGFLTHALLGDSLAAEYLILHLISTVYTRRDVLPLGKFTVNLSGCPQNSTFTEHLYRIIQHLVPASFRLQMTIENMNQLKFIPHKDYTANRLVSGLLQLPNNTSLVIDETLLEQGQLDTSGVHNVTALSNLITWQKVDYDFSYHQMEFPCSINVLVTSEGRSLLPADCQIHLQPQLIPPNMEEYMNSLLSTVLPSVLNKFRIYLTLLRFLDYNISDDITKAVEDDFVEMRKNDPQSITADDLHQLLVVARFLSLSAGQTTLSRERWLRAKQLESSRKNRLQQHKCVNGNEL", "length": 640, "header": "tr|A0A9J7JH95-1|A0A8C2QEH9_CRIGR Computationally mapped isoform of Mini-chromosome maintenance complex-binding protein OS=Cricetulus griseus OX=10029 GN=Mcmbp PE=3 SV=1 CANONICAL=A0A8C2QEH9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH95", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH95" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH95", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH95" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754052", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754052", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEH9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEH9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", 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"structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEI2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": 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"title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8C2QEI8-1", "uniprot_ac": "A0A8C2QEI8", "uniprot_id": "A0A8C2QEI8_CRIGR", "mass": { "chemical_mass": 113349.0, "monoisotopic_mass": 113349.0 }, "refseq": { "ac": "XP_027256453", "name": "histone deacetylase complex subunit SAP130 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256453" }, "gene_names": [ { "name": "Sap130", "type": "recommended", "evidence": [ { "id": "A0A8C2QEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEI8" } ] }, { "name": "Sap130", "type": "synonym", "evidence": [ { "id": "XP_027256453", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256453" } ] } ], "protein_names": [ { "name": "Histone deacetylase complex subunit SAP130 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2QEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEI8/entry#names_and_taxonomy" } ] }, { "name": "histone deacetylase complex subunit SAP130 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027256453", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256453" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027256453", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256453" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEI8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEI8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sap130", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEI8", "locus": {} } ], "crossref": [ { "id": "100755025", "url": "https://www.ncbi.nlm.nih.gov/gene/100755025", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755025", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755025", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QEI8", "url": "https://www.orthodb.org/?gene=A0A8C2QEI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13497", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13497", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13497:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13497:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027256453", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256453", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QEI8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QEI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FGW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FGW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAFTEKRLRIPQASGLNVEMSSQQFPRLGTPSPGLSQAPSQVANSGSTGLINQVATVNDESGRDADVGAREHVGASSSLPPREEKQEPVVVRPYPQVQMLPAHHAVASATPVAVTAPPAHLTPAVPLFSEGIMKPSPKPTMPSRPIAPAPPSTMSLPQKVPGQVTVTMENSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHLIHQPIQSRPPVTTSSTIPPAVVATVSATRAQSPVITTTAAHAADSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTLPSATTAGSVSHTQAPTSTIVTMTMPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPSERSSLIPISGHRASPNPVAMETRNDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSTITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTSGIQPAPIGTQGIHSAAPINTQGLQPAPMGNQQPQPEGKTSVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNTPAQGSSPRPSILRKKPTTDGMAVRKTLLPPQPPDVASPRVESSMRSASGSPRPAGAKPKSEVHVSIASPVTVSLETISNQNAEQPTIAVPPTAQQPPPAIPSMIAAASPPSQPAIALSAIPGAVPVTPPITTIAAAPTTSTPVGGSLSAVLGPPVPEIKVKEEVEPMDITRPVSTVPPLATNTVSPSLALLASNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRKEKV", "length": 1075, "header": "tr|A0A8C2QEI8-1|A0A8C2QEI8_CRIGR Isoform 1 of Histone deacetylase complex subunit SAP130 isoform X1 OS=Cricetulus griseus OX=10029 GN=Sap130 PE=3 SV=1 CANONICAL=A0A8C2QEI8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QEI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEI8/entry#A0A8C2QEI8-1", "sequence": { "sequence": "MEAFTEKRLRIPQASGLNVEMSSQQFPRLGTPSPGLSQAPSQVANSGSTGLINQVATVNDESGRDADVGAREHVGASSSLPPREEKQEPVVVRPYPQVQMLPAHHAVASATPVAVTAPPAHLTPAVPLFSEGIMKPSPKPTMPSRPIAPAPPSTMSLPQKVPGQVTVTMENSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHLIHQPIQSRPPVTTSSTIPPAVVATVSATRAQSPVITTTAAHAADSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTLPSATTAGSVSHTQAPTSTIVTMTMPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPSERSSLIPISGHRASPNPVAMETRNDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSTITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTSGIQPAPIGTQGIHSAAPINTQGLQPAPMGNQQPQPEGKTSVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNTPAQGSSPRPSILRKKPTTDGMAVRKTLLPPQPPDVASPRVESSMRSASGSPRPAGAKPKSEVHVSIASPVTVSLETISNQNAEQPTIAVPPTAQQPPPAIPSMIAAASPPSQPAIALSAIPGAVPVTPPITTIAAAPTTSTPVGGSLSAVLGPPVPEIKVKEEVEPMDITRPVSTVPPLATNTVSPSLALLASNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRKEKV", "length": 1075, "header": "tr|A0A8C2QEI8-1|A0A8C2QEI8_CRIGR Isoform 1 of Histone deacetylase complex subunit SAP130 isoform X1 OS=Cricetulus griseus OX=10029 GN=Sap130 PE=3 SV=1 CANONICAL=A0A8C2QEI8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FGW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEI8/entry#A0A9J7FGW6-1", "sequence": { "sequence": "MSSQQFPRLGTPSPGLSQAPSQVANSGSTGLINQVATVNDESGRDADVGAREHVGASSSLPPREEKQEPVVVRPYPQVQMLPAHHAVASATPVAVTAPPAHLTPAVPLFSEGIMKPSPKPTMPSRPIAPAPPSTMSLPQKVPGQVTVTMENSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHLIHQPIQSRPPVTTSSTIPPAVVATVSATRAQSPVITTTAAHAADSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTLPSATTAGSVSHTQAPTSTIVTMTMPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPSERSSLIPISGHRASPNPVAMETRNDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSTITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTSGIQPAPIGTQGIHSAAPINTQGLQPAPMGNQQPQPEGKTSVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNTPAQGSSPRPSILRKKPTTDGMAVRKTLLPPQPPDVASPRVESSMRSASGSPRPAGAKPKSEVHVSIASPVTVSLETISNQNAEQPTIAVPPTAQQPPPAIPSMIAAASPPSQPAIALSAIPGAVPVTPPITTIAAAPTTSTPVGGSLSAVLGPPVPEIKVKEEVEPMDITRPVSTVPPLATNTVSPSLALLASNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRKEKV", "length": 1055, "header": "tr|A0A9J7FGW6-1|A0A8C2QEI8_CRIGR Computationally mapped isoform of Histone deacetylase complex subunit SAP130 isoform X1 OS=Cricetulus griseus OX=10029 GN=Sap130 PE=3 SV=1 CANONICAL=A0A8C2QEI8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 778, "start_aa": "Thr", "end_pos": 778, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr778", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FGW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGW6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FGW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGW6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755025", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755025", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEI8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEI8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEK9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEK9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774301", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774301", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEK9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ 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"https://www.ncbi.nlm.nih.gov/protein/XP_035303396" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303396", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303396" } ] }, { "annotation": "Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2D1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2D1#function" }, { "database": "UniProtKB", "id": "RU363059", "url": "https://www.uniprot.org/uniprotkb/RU363059#function" }, { "database": "UniProtKB", "id": "A0A9J7H4M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2#function" }, { "database": "UniProtKB", "id": "A0A9J7H6F3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6F3#function" }, { "database": "UniProtKB", "id": "A0A8C2LRV0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRV0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Derl2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2", "locus": {} } ], "crossref": [ { "id": "A0A9J7H4M2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H4M2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100755526", "url": "https://www.ncbi.nlm.nih.gov/gene/100755526", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755526", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755526", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FKSQYWR", "url": "https://omabrowser.org/oma/group/FKSQYWR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LRV0", "url": "https://www.orthodb.org/?gene=A0A8C2LRV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H4M2", "url": "https://www.orthodb.org/?gene=A0A9J7H4M2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11009", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11009", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04511", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04511", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303396", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303396", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LRV0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LRV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2D1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2D1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6F3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6F3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6F3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVVSSCGATSSFFQQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDIFPNQPGGIRILKTPSILRTIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG", "length": 251, "header": "tr|A0A9J7H4M2-1|A0A9J7H4M2_CRIGR Isoform 1 of Derlin OS=Cricetulus griseus OX=10029 GN=Derl2 PE=3 SV=1 CANONICAL=A0A9J7H4M2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LRV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2/entry#A0A8C2LRV0-1", "sequence": { "sequence": "MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDIFPNQPGGIRILKTPSILRTIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG", "length": 239, "header": "tr|A0A8C2LRV0-1|A0A8C2LRV0_CRIGR Computationally mapped isoform of Derlin OS=Cricetulus griseus OX=10029 GN=Derl2 PE=3 SV=1 CANONICAL=A0A9J7H4M2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GCE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2/entry#A0A9J7GCE9-1", "sequence": { "sequence": "MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQVLQLGTYIFSWKIYFPISLVE", "length": 74, "header": "tr|A0A9J7GCE9-1|A0A9J7H4M2_CRIGR Computationally mapped isoform of Derlin OS=Cricetulus griseus OX=10029 GN=Derl2 PE=3 SV=1 CANONICAL=A0A9J7H4M2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2/entry#A0A9J7H2D1-1", "sequence": { "sequence": "MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDIFPNQPGGIRILKTPSILRTIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG", "length": 238, "header": "tr|A0A9J7H2D1-1|A0A9J7H2D1_CRIGR Computationally mapped isoform of Derlin OS=Cricetulus griseus OX=10029 GN=Derl2 PE=3 SV=1 CANONICAL=A0A9J7H4M2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H4M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2/entry#A0A9J7H4M2-1", "sequence": { "sequence": "MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVVSSCGATSSFFQQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDIFPNQPGGIRILKTPSILRTIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG", "length": 251, "header": "tr|A0A9J7H4M2-1|A0A9J7H4M2_CRIGR Isoform 1 of Derlin OS=Cricetulus griseus OX=10029 GN=Derl2 PE=3 SV=1 CANONICAL=A0A9J7H4M2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H6F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2/entry#A0A9J7H6F3-1", "sequence": { "sequence": "MIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDIFPNQPGGIRILKTPSILRTIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG", "length": 165, "header": "tr|A0A9J7H6F3-1|A0A9J7H6F3_CRIGR Computationally mapped isoform of Derlin OS=Cricetulus griseus OX=10029 GN=Derl2 PE=3 SV=1 CANONICAL=A0A9J7H4M2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755526", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755526", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PW06-1", "protein_name": "Derlin", "gene_name": "DERL2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAYQTFRQEYLQVPPVTRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQVWRLITNYLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTIFGLFVNLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLIFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDVFPNQPGGGRLLRTPSVLKAIFDTPEDDPNYNPLPEERPGGFAWGEGQRLGG", "length": 239 }, "evidence": [ { "id": "A0A9J7H4M2", "url": "https://omabrowser.org/oma/group/A0A9J7H4M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A286ZJW9-1", "protein_name": "Derlin", "gene_name": "DERL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG", "length": 239 }, "evidence": [ { "id": "A0A9J7H4M2", "url": "https://omabrowser.org/oma/group/A0A9J7H4M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AMH0-1", "protein_name": "Derlin", "gene_name": "Derl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDIFPNQPGGIRILKTPSILRTIFDTPDEDPNYNPLPEERPGGFAWGWDKTDHD", "length": 239 }, "evidence": [ { "id": "A0A9J7H4M2", "url": "https://omabrowser.org/oma/group/A0A9J7H4M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54NN1-1", "protein_name": "Probable derlin-2 homolog", "gene_name": "derl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAQPFEDWYKNLPIVTKIYMTGCVVTSVSVYLGLVGPLRLYLNFPLVFGKYEFWRLFTNFFFYDEIGMNFFFHMYFLVRHSRLLEESSFRGRSADYLFMWIFGSFLLLIMDAFLFYTKIVTKVLFLAPSIAFMVIYVWSRRNPNMHISFLGLFTFSAPYLPWVILIMGYLFNHDLTTDLLGAVAGHAYYFLEDAYPLISNRRLLKTPGFLKNLMDGQEQPIVDAHQQQEVQQAQQQEVQQPVQNFLNEDDLDQQ", "length": 254 }, "evidence": [ { "id": "A0A9J7H4M2", "url": "https://omabrowser.org/oma/group/A0A9J7H4M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BNI4-1", "protein_name": "Derlin-2", "gene_name": "Derl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDIFPNQPGGIRILKTPSILRTIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG", "length": 239 }, "evidence": [ { "id": "A0A9J7H4M2", "url": "https://omabrowser.org/oma/group/A0A9J7H4M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9GZP9-1", "protein_name": "Derlin-2", "gene_name": "DERL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG", "length": 239 }, "evidence": [ { "id": "A0A9J7H4M2", "url": "https://omabrowser.org/oma/group/A0A9J7H4M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VEU2-1", "protein_name": "Derlin", "gene_name": "Der-2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNALRQFYLEIPVVTRAYTTVCVLTTLAVHLDLVSPLQLYFNPTLIVRKFQIWRLATTFLYFGTIGISFFFNMVFTYRYCRMLEDGSFRGRSSDFVMMFIFGGVLMTFFGIFVNLLFLGQAFTLMLVYVWSRRNPLVPMNFFGVLNFQAPYLPWVLLCCSMILGNTVWVDVIGMGVGHIYYVLEDVYPTLSNGYRLIKTPYFLKRLFNEHIERNFQAAAEDRPGGFPWGGEGQPLLPEEIAADGQDEEPANRAAPVAAAPQ", "length": 261 }, "evidence": [ { "id": "A0A9J7H4M2", "url": "https://omabrowser.org/oma/group/A0A9J7H4M2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9ZS88-1", "protein_name": "Derlin-2.2", "gene_name": "DER2.2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQAVEEWYKQMPIITRSYLTAAVITTVGCSLDIISPYNLYLNPTLVVKQYQYWRLVTNFLYFRKMDLDFMFHMFFLARYCKLLEENSFRGKTADFLYMLLFGASVLTGIVLIGGMIPYLSASFAKIIFLSNSLTFMMVYVWSKQNPYIHMSFLGLFTFTAAYLPWVLLGFSILVGASAWVDLLGMIAGHAYYFLAEVYPRMTNRRPLKTPSFLKALFADEPVVVARPEDVRFAAAPFDEIHQD", "length": 244 }, "evidence": [ { "id": "A0A9J7H4M2", "url": "https://omabrowser.org/oma/group/A0A9J7H4M2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "proteasomal protein catabolic process", "id": "GO:0010498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010498", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2" } ], "pmid": "" }, { "name": "cellular response to stress", "id": "GO:0033554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033554", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2" } ], "pmid": "" }, { "name": "retrograde protein transport, ER to cytosol", "id": "GO:0030970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030970", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2" } ], "pmid": "" }, { "name": "negative regulation of retrograde protein transport, ER to cytosol", "id": "GO:1904153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904153", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signal recognition particle binding", "id": "GO:0005047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005047", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M2", "url": 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ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027277672", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277672" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JTV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTV8#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A9J7JV99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JV99#function" }, { "database": "UniProtKB", "id": "A0A9J7H285", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H285#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H285", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H285" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100757091", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H285", "locus": {} } ], "crossref": [ { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757091", "url": "https://www.ncbi.nlm.nih.gov/gene/100757091", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757091", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757091", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H285", "url": "https://www.orthodb.org/?gene=A0A9J7H285", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14196", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14196", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14196:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14196:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027277672", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277672", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H285", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H285", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H285-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H285-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JV99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JV99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JV99-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JV99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCQANEGLQSKMTFSTLSLWPSQKLTEQTSVTFEDVAVTFTDEEWRHLVPVQRALYKTVMLETYETIISLGIPIPWSDVILQLEKRDKPWTQGLLGSKEKEWPESISLDQETKPENLAASEGTLGESHRQQSPLCPKPKVQTLAGGSGPEKERLEAETCKKPLSLDKSLKGRSAPSKKILTKRQDQECRDCGKTFFDHSSLIRHQRTHTGEKPYDCPECGKAFSHRSSLSRHLMSHTGESPYECSVCGKAFFDRSSLTVHLRIHTGEKPFKCSECGKAFFDRSSLTRHQRIHTGESPYECQQCGKAFSQKSILTRHQLIHTGRKQYVCSECGKAFYGVSSLNRHQKEHNGEPHHQCNECGKAFFDRSSLTQHQKIHTGDKPYECSVCGKAFSQRCRLTQHQRVHTGEKPFECSVCGKEFSFKSSVIQHQRRYAKQGTD", "length": 438, "header": "tr|A0A9J7H285-1|A0A9J7H285_CRIGR Isoform 1 of Zinc finger protein 661 OS=Cricetulus griseus OX=10029 GN=LOC100757091 PE=3 SV=1 CANONICAL=A0A9J7H285-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H285-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H285/entry#A0A9J7H285-1", "sequence": { "sequence": "MCQANEGLQSKMTFSTLSLWPSQKLTEQTSVTFEDVAVTFTDEEWRHLVPVQRALYKTVMLETYETIISLGIPIPWSDVILQLEKRDKPWTQGLLGSKEKEWPESISLDQETKPENLAASEGTLGESHRQQSPLCPKPKVQTLAGGSGPEKERLEAETCKKPLSLDKSLKGRSAPSKKILTKRQDQECRDCGKTFFDHSSLIRHQRTHTGEKPYDCPECGKAFSHRSSLSRHLMSHTGESPYECSVCGKAFFDRSSLTVHLRIHTGEKPFKCSECGKAFFDRSSLTRHQRIHTGESPYECQQCGKAFSQKSILTRHQLIHTGRKQYVCSECGKAFYGVSSLNRHQKEHNGEPHHQCNECGKAFFDRSSLTQHQKIHTGDKPYECSVCGKAFSQRCRLTQHQRVHTGEKPFECSVCGKEFSFKSSVIQHQRRYAKQGTD", "length": 438, "header": "tr|A0A9J7H285-1|A0A9J7H285_CRIGR Isoform 1 of Zinc finger protein 661 OS=Cricetulus griseus OX=10029 GN=LOC100757091 PE=3 SV=1 CANONICAL=A0A9J7H285-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JTV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H285/entry#A0A9J7JTV8-1", "sequence": { "sequence": "MLETYETIISLGIPIPWSDVILQLEKRDKPWTQGLLGSKEKEWPESISLDQETKPENLAASEGTLGESHRQQSPLCPKPKVQTLAGGSGPEKERLEAETCKKPLSLDKSLKGRSAPSKKILTKRQDQECRDCGKTFFDHSSLIRHQRTHTGEKPYDCPECGKAFSHRSSLSRHLMSHTGESPYECSVCGKAFFDRSSLTVHLRIHTGEKPFKCSECGKAFFDRSSLTRHQRIHTGESPYECQQCGKAFSQKSILTRHQLIHTGRKQYVCSECGKAFYGVSSLNRHQKEHNGEPHHQCNECGKAFFDRSSLTQHQKIHTGDKPYECSVCGKAFSQRCRLTQHQRVHTGEKPFECSVCGKEFSFKSSVIQHQRRYAKQGTD", "length": 379, "header": "tr|A0A9J7JTV8-1|A0A9J7H285_CRIGR Computationally mapped isoform of Zinc finger protein 661 OS=Cricetulus griseus OX=10029 GN=LOC100757091 PE=3 SV=1 CANONICAL=A0A9J7H285-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JV99-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H285/entry#A0A9J7JV99-1", "sequence": { "sequence": "MCQTSVTFEDVAVTFTDEEWRHLVPVQRALYKTVMLETYETIISLGIPIPWSDVILQLEKRDKPWTQGLLGSKEKEWPESISLDQETKPENLAASEGTLGESHRQQSPLCPKPKVQTLAGGSGPEKERLEAETCKKPLSLDKSLKGRSAPSKKILTKRQDQECRDCGKTFFDHSSLIRHQRTHTGEKPYDCPECGKAFSHRSSLSRHLMSHTGESPYECSVCGKAFFDRSSLTVHLRIHTGEKPFKCSECGKAFFDRSSLTRHQRIHTGESPYECQQCGKAFSQKSILTRHQLIHTGRKQYVCSECGKAFYGVSSLNRHQKEHNGEPHHQCNECGKAFFDRSSLTQHQKIHTGDKPYECSVCGKAFSQRCRLTQHQRVHTGEKPFECSVCGKEFSFKSSVIQHQRRYAKQGTD", "length": 413, "header": "tr|A0A9J7JV99-1|A0A9J7H285_CRIGR Computationally mapped isoform of Zinc finger protein 661 OS=Cricetulus griseus OX=10029 GN=LOC100757091 PE=3 SV=1 CANONICAL=A0A9J7H285-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JTV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTV8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JTV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTV8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757091", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757091", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H285", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H285" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H285", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H285" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H285", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H285" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H285", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H285" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H285", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H285" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H285" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 186, "end_pos": 213, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H285" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 102, "start_aa": "Val", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H384-1", "uniprot_ac": "A0A9J7H384", "uniprot_id": "A0A9J7H384_CRIGR", "mass": { "chemical_mass": 54244.0, "monoisotopic_mass": 54244.0 }, "refseq": { "ac": "XP_035303321", "name": "ETS translocation variant 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303321" }, "gene_names": [ { "name": "LOC103158999", "type": "recommended", "evidence": [ { "id": "A0A9J7H384", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384" } ] }, { "name": "LOC103158999", "type": "synonym", "evidence": [ { "id": "XP_035303321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303321" } ] } ], "protein_names": [ { "name": "ETS translocation variant 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035303321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303321" }, { "id": "A0A9J7H384", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303321", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303321" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H384", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC103158999", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384", "locus": {} } ], "crossref": [ { "id": "103158999", "url": "https://www.ncbi.nlm.nih.gov/gene/103158999", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103158999", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103158999", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H384", "url": "https://www.orthodb.org/?gene=A0A9J7H384", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849:SF181", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849:SF181", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303321", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303321", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H0L0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0L0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0L0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H295", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H295", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H295-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H295-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H384", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H384-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3X2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3X2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4J0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4J0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4J0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4J0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H584", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H584", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H584-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H584-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5K5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5K5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5K5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6B3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6B3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K7T7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7T7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K7T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7T7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBD1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERRMKGGYLDQRVPYTFCSQKSPGNGSLGEALMVPQGKLMDPGSLPPSDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTEPALSCSRKPPLPYHHGEQCLYSSAYDSPRQIAIKSPAPGAPGQSPLQPFPRAEQQQSLLRTSSSSQSHPGHGYLGEHSSVFQQPLDMCHSFTSPQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAATQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSGPSPGDGVIGYGYEKSLRPFPDDVCIVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFSHKGGYSY", "length": 487, "header": "tr|A0A9J7H384-1|A0A9J7H384_CRIGR Isoform 1 of ETS translocation variant 4 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC103158999 PE=3 SV=1 CANONICAL=A0A9J7H384-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H0L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384/entry#A0A9J7H0L0-1", "sequence": { "sequence": "MERRMKGGYLDQRVPYTFCSQKSPGNGSLGEALMVPQGKLMDPGSLPPSDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENSFHSPTTRIKKEPQSPRTEPALSCSRKPPLPYHHGEQCLYSSAYDSPRQIAIKSPAPGAPGQSPLQPFPRAEQQQSLLRTSSSSQSHPGHGYLGEHSSVFQQPLDMCHSFTSPQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAATQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSGPSPGDGVIGYGYEKSLRPFPDDVCIVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFSHKGGYSY", "length": 486, "header": "tr|A0A9J7H0L0-1|A0A9J7H0L0_CRIGR Computationally mapped isoform of ETS translocation variant 4 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC103158999 PE=3 SV=1 CANONICAL=A0A9J7H384-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H295-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384/entry#A0A9J7H295-1", "sequence": { "sequence": "MERRMKGGYLDQRVPYTFCSKSPGNGSLGEALMVPQGKLMDPGSLPPSDSEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTEPALSCSRKPPLPYHHGEQCLYSSAYDSPRQIAIKSPAPGAPGQSPLQPFPRAEQQQSLLRTSSSSQSHPGHGYLGEHSSVFQQPLDMCHSFTSPQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAATQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSGPSPGDGVIGYGYEKSLRPFPDDVCIVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFSHKGGYSY", "length": 470, "header": "tr|A0A9J7H295-1|A0A9J7H384_CRIGR Computationally mapped isoform of ETS translocation variant 4 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC103158999 PE=3 SV=1 CANONICAL=A0A9J7H384-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H384-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384/entry#A0A9J7H384-1", "sequence": { "sequence": "MERRMKGGYLDQRVPYTFCSQKSPGNGSLGEALMVPQGKLMDPGSLPPSDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTEPALSCSRKPPLPYHHGEQCLYSSAYDSPRQIAIKSPAPGAPGQSPLQPFPRAEQQQSLLRTSSSSQSHPGHGYLGEHSSVFQQPLDMCHSFTSPQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAATQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSGPSPGDGVIGYGYEKSLRPFPDDVCIVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFSHKGGYSY", "length": 487, "header": "tr|A0A9J7H384-1|A0A9J7H384_CRIGR Isoform 1 of ETS translocation variant 4 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC103158999 PE=3 SV=1 CANONICAL=A0A9J7H384-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H3X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384/entry#A0A9J7H3X2-1", "sequence": { "sequence": "MQLPGSCPPAPSQHHPSLLSCLFPPAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTEPALSCSRKPPLPYHHGEQCLYSSAYDSPRQIAIKSPAPGAPGQSPLQPFPRAEQQQSLLRTSSSSQSHPGHGYLGEHSSVFQQPLDMCHSFTSPQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAATQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSGPSPGDGVIGYGYEKSLRPFPDDVCIVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFSHKGGYSY", "length": 444, "header": "tr|A0A9J7H3X2-1|A0A9J7H3X2_CRIGR Computationally mapped isoform of ETS translocation variant 4 isoform X10 OS=Cricetulus griseus OX=10029 GN=LOC103158999 PE=3 SV=1 CANONICAL=A0A9J7H384-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H4J0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384/entry#A0A9J7H4J0-1", "sequence": { "sequence": "MERRMKGGYLDQRVPYTFCSQKSPGNGSLGEALMVPQGKLMDPGSLPPSDSEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTEPALSCSRKPPLPYHHGEQCLYSSAYDSPRQIAIKSPAPGAPGQSPLQPFPRAEQQQSLLRTSSSSQSHPGHGYLGEHSSVFQQPLDMCHSFTSPQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAATQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSGPSPGDGVIGYGYEKSLRPFPDDVCIVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFSHKGGYSY", "length": 471, "header": "tr|A0A9J7H4J0-1|A0A9J7H4J0_CRIGR Computationally mapped isoform of ETS translocation variant 4 isoform X7 OS=Cricetulus griseus OX=10029 GN=LOC103158999 PE=3 SV=1 CANONICAL=A0A9J7H384-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H584-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384/entry#A0A9J7H584-1", "sequence": { "sequence": "MERRMKGGYLDQRVPYTFCSKSPGNGSLGEALMVPQGKLMDPGSLPPSDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTEPALSCSRKPPLPYHHGEQCLYSRQIAIKSPAPGAPGQSPLQPFPRAEQQQSLLRTSSSSQSHPGHGYLGEHSSVFQQPLDMCHSFTSPQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAATQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSGPSPGDGVIGYGYEKSLRPFPDDVCIVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFSHKGGYSY", "length": 480, "header": "tr|A0A9J7H584-1|A0A9J7H584_CRIGR Computationally mapped isoform of ETS translocation variant 4 isoform X6 OS=Cricetulus griseus OX=10029 GN=LOC103158999 PE=3 SV=1 CANONICAL=A0A9J7H384-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H5K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384/entry#A0A9J7H5K5-1", "sequence": { "sequence": "MERRMKGGYLDQRVPYTFCSKSPGNGSLGEALMVPQGKLMDPGSLPPSDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENSFHSPTTRIKKEPQSPRTEPALSCSRKPPLPYHHGEQCLYSSAYDSPRQIAIKSPAPGAPGQSPLQPFPRAEQQQSLLRTSSSSQSHPGHGYLGEHSSVFQQPLDMCHSFTSPQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAATQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSGPSPGDGVIGYGYEKSLRPFPDDVCIVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFSHKGGYSY", "length": 485, "header": "tr|A0A9J7H5K5-1|A0A9J7H5K5_CRIGR Computationally mapped isoform of ETS translocation variant 4 isoform X4 OS=Cricetulus griseus OX=10029 GN=LOC103158999 PE=3 SV=1 CANONICAL=A0A9J7H384-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H6B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384/entry#A0A9J7H6B3-1", "sequence": { "sequence": "MERRMKGGYLDQRVPYTFCSQKSPGNGSLGEALMVPQGKLMDPGSLPPSDSEAQVPDSDEQFVPDFHSENSFHSPTTRIKKEPQSPRTEPALSCSRKPPLPYHHGEQCLYSSAYDSPRQIAIKSPAPGAPGQSPLQPFPRAEQQQSLLRTSSSSQSHPGHGYLGEHSSVFQQPLDMCHSFTSPQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAATQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSGPSPGDGVIGYGYEKSLRPFPDDVCIVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFSHKGGYSY", "length": 470, "header": "tr|A0A9J7H6B3-1|A0A9J7H6B3_CRIGR Computationally mapped isoform of ETS translocation variant 4 isoform X9 OS=Cricetulus griseus OX=10029 GN=LOC103158999 PE=3 SV=1 CANONICAL=A0A9J7H384-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K7T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384/entry#A0A9J7K7T7-1", "sequence": { "sequence": "MERRMKGGYLDQRVPYTFCSKSPGNGSLGEALMVPQGKLMDPGSLPPSDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTEPALSCSRKPPLPYHHGEQCLYSSAYDSPRQIAIKSPAPGAPGQSPLQPFPRAEQQQSLLRTSSSSQSHPGHGYLGEHSSVFQQPLDMCHSFTSPQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAATQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSGPSPGDGVIGYGYEKSLRPFPDDVCIVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFSHKGGYSY", "length": 486, "header": "tr|A0A9J7K7T7-1|A0A9J7H384_CRIGR Computationally mapped isoform of ETS translocation variant 4 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC103158999 PE=3 SV=1 CANONICAL=A0A9J7H384-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384/entry#A0A9J7KBD1-1", "sequence": { "sequence": "MERRMKGGYLDQRVPYTFCSQKSPGNGSLGEALMVPQGKLMDPGSLPPSDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTEPALSCSRKPPLPYHHGEQCLYSRQIAIKSPAPGAPGQSPLQPFPRAEQQQSLLRTSSSSQSHPGHGYLGEHSSVFQQPLDMCHSFTSPQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAATQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSGPSPGDGVIGYGYEKSLRPFPDDVCIVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFSHKGGYSY", "length": 481, "header": "tr|A0A9J7KBD1-1|A0A9J7H384_CRIGR Computationally mapped isoform of ETS translocation variant 4 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC103158999 PE=3 SV=1 CANONICAL=A0A9J7H384-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K7T7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7T7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K7T7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7T7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103158999", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103158999", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H384", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H384", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H384", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H384", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H384", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H384" } 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"comment": "", "icn3d_view": {}, "start_pos": 682, "start_aa": "Thr", "end_pos": 682, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr682", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8C2N386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N386" } ] } ] }, { "uniprot_ac": "A0A8C2QH91", "gene_name": "Ino80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8C2QH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH91" } ] } ] }, { "uniprot_ac": "A0A8C2QHV1", "gene_name": "Ddx20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] } ] }, { "uniprot_ac": "A0A8C2QLX9", "gene_name": "Ddx52", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QLX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLX9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QLX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLX9" } ] } ] }, { "uniprot_ac": "A0A8C2QM19", "gene_name": "Clpx", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QM19" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8C2QM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QM19" } ] } ] }, { "uniprot_ac": "A0A8C2QNE7", "gene_name": "Eif4a3", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNE7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNE7" } ] } ] }, { "uniprot_ac": "A0A9J7F1E5", "gene_name": "Hltf", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A9J7F1E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A9J7F1E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E5" } ] } ] }, { "uniprot_ac": "A0A9J7F876", "gene_name": "Ddx11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7F876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F876" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7F876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F876" } ] } ] }, { "uniprot_ac": "A0A9J7F9W3", "gene_name": "Zgrf1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7F9W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9W3" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7F9W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9W3" } ] } ] }, { "uniprot_ac": "A0A9J7FCH5", "gene_name": "Mov10l1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCH5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCH5" } ] } ] }, { "uniprot_ac": "A0A9J7FI19", "gene_name": "Xrcc6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] } ] }, { "uniprot_ac": "A0A9J7FI42", "gene_name": "Fbh1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI42" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI42" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FJ37", "gene_name": "Mcm9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ37" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ37" } ] } ] }, { "uniprot_ac": "A0A9J7FPD0", "gene_name": "Dhx32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FPD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FPD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPD0" } ] } ] }, { "uniprot_ac": "A0A9J7FPK3", "gene_name": "Twnk", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7FPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPK3" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7FPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPK3" } ] } ] }, { "uniprot_ac": "A0A9J7FTT2", "gene_name": "Mcm5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A9J7FTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT2" } ] } ] }, { "uniprot_ac": "A0A9J7FU33", "gene_name": "Eif4a2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FU33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU33" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FU33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU33" } ] } ] }, { "uniprot_ac": "A0A9J7FUH6", "gene_name": "Polq", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] } ] }, { "uniprot_ac": "A0A9J7FV95", "gene_name": "LOC100751095", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A9J7FV95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV95" } ] } ] }, { "uniprot_ac": "A0A9J7FXI2", "gene_name": "Ddx10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FXI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXI2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FXI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXI2" } ] } ] }, { "uniprot_ac": "A0A9J7FYM8", "gene_name": "Ddx54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYM8" } ] } ] }, { "uniprot_ac": "A0A9J7G1N4", "gene_name": "Fancm", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G1N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1N4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G1N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1N4" } ] } ] }, { "uniprot_ac": "A0A9J7G2T1", "gene_name": "Dhx9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G2T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G2T1", "database": "UniProtKB", "url": 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H(+).", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M1" } ] }, { "ec_number": "2.7.8.41", "activity": "", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M1" } ] } ] }, { "uniprot_ac": "A0A9J7G7R5", "gene_name": "Setx", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G7R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7R5" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G7R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7R5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": 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"activity": "", "evidence": [ { "id": "A0A9J7GCV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1" } ] } ] }, { "uniprot_ac": "A0A9J7GDX9", "gene_name": "Hfm1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7GDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9" } ] } ] }, { "uniprot_ac": "A0A9J7GF88", "gene_name": "Dhx33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GF88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF88" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7GF88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF88" } ] } ] }, { "uniprot_ac": "A0A9J7GHR4", "gene_name": "Ercc2", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7GHR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHR4" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7GHR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHR4" } ] } ] }, { "uniprot_ac": "A0A9J7GID0", "gene_name": "LOC103158905", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GID0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GID0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7GID0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GID0" } ] } ] }, { "uniprot_ac": "A0A9J7GN75", 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"ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A9J7GRQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRQ0" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A9J7GRQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRQ0" } ] } ] }, { "uniprot_ac": "A0A9J7H1K5", "gene_name": "LOC100755041", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7H1K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1K5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7H1K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1K5" } ] } ] }, { "uniprot_ac": "A0A9J7H2C5", "gene_name": "LOC100764541", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7H2C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2C5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7H2C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2C5" } ] } ] }, { "uniprot_ac": "A0A9J7H2D3", "gene_name": "Rnf213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A9J7H2D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2D3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A9J7H2D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2D3" } ] } ] }, { "uniprot_ac": "A0A9J7H2L4", "gene_name": "Rhot1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A9J7H2L4", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7H9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9J6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7H9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9J6" } ] } ] }, { "uniprot_ac": "A0A9J7HCU3", "gene_name": "LOC118237676", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7HCU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCU3" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7HCU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCU3" } ] } ] }, { "uniprot_ac": "A0A9J7JEW1", "gene_name": "Smpdl3a", "activity": [ { "ec_number": "3.6.1.15", "activity": 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"evidence": [ { "id": "A0A9J7JQ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQ85" } ] } ] }, { "uniprot_ac": "A0A9J7JQY5", "gene_name": "Ddx59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7JQY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQY5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7JQY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQY5" } ] } ] }, { "uniprot_ac": "A0A9J7JR19", "gene_name": "Ifih1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7JR19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JR19" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7JR19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JR19" } ] } ] }, { 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phosphate + H(+).", "evidence": [ { "id": "A0A9J7JVX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVX0" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7JVX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVX0" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A9J7JVX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVX0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7JVX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVX0" } ] } ] }, { "uniprot_ac": "A0A9J7K1D9", "gene_name": "Dhx34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7K1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1D9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7K1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1D9" } ] } ] }, { "uniprot_ac": "A0A9J7K2R5", "gene_name": "Atrx", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7K2R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2R5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A9J7K2R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2R5" } ] } ] }, { "uniprot_ac": "A0A9J7K381", "gene_name": "Cftr", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A9J7K381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K381" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A9J7K381", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3IEZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IEZ7" } ] } ] }, { "uniprot_ac": "G3IG24", "gene_name": "Ddx19b", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3IG24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IG24" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3IG24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IG24" } ] } ] }, { "uniprot_ac": "G3IJD1", "gene_name": "Ddx17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3IJD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IJD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3IJD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IJD1" } ] } ] }, { 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"isoforms": [ { "isoform_ac": "A0A9J7H2H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H0/entry#A0A9J7H2H0-1", "sequence": { "sequence": "MGDGKSLRAGYNSITFWKSKFKTLLARALYDNRPDCSDELAFFRGDILTIVEQNVPESEGWWKCLLHGRQGLAPANRLQVLKETPADRPCPQLLDTDLTGSEALYQVPSLFCPPPPGPVYEPMKSWVEGPTPATAQVYELPDSPSSARIICEKPLSFPKQTLYVLPRPTRASLPTLPSQVYDVPVQSKVSSTLKMPENRQFYDIPTSSQKAALHSSASQASGQSVVLTPTTAFRQDGGYRMSSSPQKSEWMNDAPVLLGKANIRNAPLTSFTRESGSSAVPGSTSAVPIGAVTHPPQLGSTGQKSRLPEEPSYAVPAPRGSLPSDSGSSYRVPSRFLIPRVEQQNTKPNIYDTPKTMHGVSQAGKELEKVKEVPENIPWISRHTNSLFPDSDQLSVASSDSRASVVSSCSSVSMDSSQGSSSEDSAKELWMDTEFAREMAMALQHKVASSVAGLLLFVSRTWRFKDSLEVNVHTIRRAADNIEEALREFLDFAQGVGETARNLTDSQLQARIRDQLQIISGSYQTLLDAKGSLDHCNWSLEVLVTDKVQSNLDDLETFVMVARMVPEDVKRFTSIVIANGRLLFKRNCEKGETELKCEKCSQPPQRETESYQKSSPFNKQLANERRLELVRKNRVHVCGQKPPNLQEKGEPILERRSDENKDFHATSPSSLSSPPPSRQDADRKIHLSEHCRLYFGALFKAISVFTSSLGNSQPPEVFITQSKLVITVGQKLVDTLCKETQDKDERNEILRGSSHLCGLLKDLALATKNAVIKYPSPSALGCLQTEVEKLEYQTRKFRETLE", "length": 802, "header": "tr|A0A9J7H2H0-1|A0A9J7H2H0_CRIGR Isoform 1 of Cas scaffolding protein family member 4 OS=Cricetulus griseus OX=10029 GN=Cass4 PE=3 SV=1 CANONICAL=A0A9J7H2H0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 131, "start_aa": "Thr", "end_pos": 131, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr131", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2H0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764252", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764252", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2H0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H0" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2H0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2H0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H0" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2H0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2H0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H0" } ], "pmid": "" }, { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", 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"MPSQGSNQDFRNLQAKFQASQQEPGEPSRKPPKPEFNKLLKKFPQTELSEQPKKASQTEFGIVSLKPLQMQFAELPKKPSQSEVLRKSPQPEFTELPKKSLQSELKDLPRKPLHLEFTGLKKPSQTQFTASKKPPEPQFASPPKAPQPEFINLPKMLPKHEFGELTKKSPPLEAPQEPIVPAQKPRKPEFSNPAKPPVELKPITVPKKFWQQESSEAPLKPLPPESSTFPKKSLQPQAAGFSRKSLTQSEPSEIPQTSLSKPGSSEFYPRSPQPDVSNFPKKSLQSEFSDKIPYPQAIGCPKSPQQSMSYEVPQTPPWKPESCNPPSHSPKPDFHVFPKKHPQLQVSDLTRTSSEPEVHRVPKKPQQPDLQALSKKPSQPELGHLPRTSSEPEFGLLPRKSLQPDFAKALPRKPKLPGSVSECSLPSAFASSSPQFSLSPGYGVPGTPGWRSEDFQIRHPPRRRPLPSVSSLGSPPAKPPLPPVPINIQSFRRASATATAVLKSGSSGTHFPAQQLQHISQNPDEIYELYDAVEATGDSSLSPRGRDEVQSTQRTTRLPLQDTELRKNASQPQQPLPTDPKLLKQIRKAEKAEREFRKKFKFEGEIVIHTKMMIDPNAKTRRGGGKHLGIRRGEILEVIEFTNKDEMLCRDPKGKYGYVPRTALLPL", "length": 667, "header": "tr|A0A9J7H2H1-1|A0A9J7H2H1_CRIGR Isoform 1 of PML-RARA-regulated adapter molecule 1 OS=Cricetulus griseus OX=10029 GN=Pram1 PE=4 SV=1 CANONICAL=A0A9J7H2H1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H2H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H1/entry#A0A9J7H2H1-1", "sequence": { 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755895", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755895", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H1" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H1" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H2H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H1" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 591, "end_pos": 667, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 447 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 568, "end_pos": 570 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H2H2-1", "uniprot_ac": "A0A9J7H2H2", "uniprot_id": "A0A9J7H2H2_CRIGR", "mass": { "chemical_mass": 20582.0, "monoisotopic_mass": 20582.0 }, "refseq": { "ac": "XP_035303700", "name": "tachykinin-4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303700" }, "gene_names": [ { "name": "Tac4", "type": "recommended", "evidence": [ { "id": "A0A9J7H2H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H2" } ] }, { "name": "Tac4", "type": "synonym", "evidence": [ { "id": "XP_035303700", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303700" } ] } ], "protein_names": [ { "name": "Tachykinin-4 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7H2H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H2/entry#names_and_taxonomy" } ] }, { "name": "tachykinin-4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035303700", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303700" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303700", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303700" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2H2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tac4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H2", "locus": {} } ], "crossref": [ { "id": "A0A9J7H2H2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H2H2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100761569", "url": "https://www.ncbi.nlm.nih.gov/gene/100761569", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761569", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761569", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EAESWVT", "url": "https://omabrowser.org/oma/group/EAESWVT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H2H2", "url": "https://www.orthodb.org/?gene=A0A9J7H2H2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JVH2", "url": "https://www.orthodb.org/?gene=A0A9J7JVH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11250", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11250", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11250:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11250:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_035303700", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303700", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H1A8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1A8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2H2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JVH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JVH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPLLALLLLIGPSVCTTTGDREQLTLGTAAESWVTVNLKGIPVASIELQLQEMKRSRTRQFYGLMGKRLEGIRPIQPKARMGYQLGRIMQDLLGERGLFVEVLYLTSGSFLFPDGTLATGKKDRMNCFSLEIFSGNLQTGDTPPECRAWSSGHRRPSESKRESRLSPSPATCSSLPGHRRGWPGF", "length": 186, "header": "tr|A0A9J7H2H2-1|A0A9J7H2H2_CRIGR Isoform 1 of Tachykinin-4 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tac4 PE=3 SV=1 CANONICAL=A0A9J7H2H2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H1A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H2/entry#A0A9J7H1A8-1", "sequence": { "sequence": "MLPLLALLLLIGPSVCTTTGDREQLTLGTAAESWVTVNLKGIPVASIELQLQEMKRSRTRQFYGLMGKRLEGIRPIQPKARMGYQLGRIMQDLLGERGLFVEGYHSPSCGG", "length": 111, "header": "tr|A0A9J7H1A8-1|A0A9J7H1A8_CRIGR Computationally mapped isoform of Tachykinin-4 isoform X3 OS=Cricetulus griseus OX=10029 GN=Tac4 PE=3 SV=1 CANONICAL=A0A9J7H2H2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H2/entry#A0A9J7H2H2-1", "sequence": { "sequence": "MLPLLALLLLIGPSVCTTTGDREQLTLGTAAESWVTVNLKGIPVASIELQLQEMKRSRTRQFYGLMGKRLEGIRPIQPKARMGYQLGRIMQDLLGERGLFVEVLYLTSGSFLFPDGTLATGKKDRMNCFSLEIFSGNLQTGDTPPECRAWSSGHRRPSESKRESRLSPSPATCSSLPGHRRGWPGF", "length": 186, "header": "tr|A0A9J7H2H2-1|A0A9J7H2H2_CRIGR Isoform 1 of Tachykinin-4 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tac4 PE=3 SV=1 CANONICAL=A0A9J7H2H2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JVH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2H2/entry#A0A9J7JVH2-1", "sequence": { "sequence": "MLPLLALLLLIGPSVCTTTGDREQLTLGTAAESWVTVNLKGIPVASIELQLQEMKRSRTRQFYGLMGKRLEGIRPIQPKARMGYQLGRIMQDLLGERGLFVEGTCRQETHHQSAGPGAVAIEGLQSQRGSPDSLHHQQRVALSLGTEEDGQGSE", "length": 154, "header": "tr|A0A9J7JVH2-1|A0A9J7H2H2_CRIGR Computationally mapped isoform of Tachykinin-4 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tac4 PE=3 SV=1 CANONICAL=A0A9J7H2H2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference 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OS=Cricetulus griseus OX=10029 GN=Lrfn5 PE=3 SV=1 CANONICAL=A0A9J7H2J2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 691, "start_aa": "Thr", "end_pos": 691, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr691", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2J2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2J2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 452, "end_pos": 454, "annotation": "n_glycosylation_sequon" }, { "start_pos": 671, "end_pos": 673, "annotation": "n_glycosylation_sequon" }, { "start_pos": 672, "end_pos": 674, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { 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eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303372", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303372" } ] }, { "annotation": "Component of the large ribosomal subunit. 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"sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H2L9-1", "uniprot_ac": "A0A9J7H2L9", "uniprot_id": "A0A9J7H2L9_CRIGR", "mass": { "chemical_mass": 109789.0, "monoisotopic_mass": 109789.0 }, "refseq": { "ac": "XP_035302542", "name": "oxysterol-binding protein-related protein 6 isoform X7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302542" }, "gene_names": [ { "name": "Osbpl6", "type": "recommended", "evidence": [ { "id": "A0A9J7H2L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9" } ] }, { "name": "Osbpl6", "type": "synonym", "evidence": [ { "id": "XP_035302542", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302542" } ] } ], "protein_names": [ { "name": "Oxysterol-binding protein", "type": "recommended", "evidence": [ { "id": "A0A9J7H2L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9/entry#names_and_taxonomy" } ] }, { "name": "oxysterol-binding protein-related protein 6 isoform X7", "type": "synonym", "evidence": [ { "id": "XP_035302542", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302542" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302542", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302542" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2L9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Osbpl6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9", "locus": {} } ], "crossref": [ { "id": "A0A9J7H2L9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H2L9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13287", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13287", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765045", "url": "https://www.ncbi.nlm.nih.gov/gene/100765045", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765045", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765045", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H2L9", "url": "https://www.orthodb.org/?gene=A0A9J7H2L9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972:SF76", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972:SF76", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302542", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302542", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H0F6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0F6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0F6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0F6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H195", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H195", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H195-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H195-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2L9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZQ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K936", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K936", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K936-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K936-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSDEKGISPAHKTSTPTHRSASSSTSSQRESRQSIHVLERTASSGTEPSVSRQLLEPEPIPLSKEADSWEIIEGLKIGQTNVQKPDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPATSTAESSPAANVSVVDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQEGPPAKGQFNTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHNKGHSTQMARLRQSLSQSEGASKSWALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEASEQIHVNLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "length": 967, "header": "tr|A0A9J7H2L9-1|A0A9J7H2L9_CRIGR Isoform 1 of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbpl6 PE=3 SV=1 CANONICAL=A0A9J7H2L9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H0F6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9/entry#A0A9J7H0F6-1", "sequence": { "sequence": "MSSDEKGISPAHKTSTPTHRSASSSTSSQRESRQSIHVLERTASSGTEPSVSRQLLEPEPIPLSKEADSWEIIEGLKIGQTNVQKPDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPATSTAESSPAANVSVVDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHNKGHSTQMARLRQSLSQASEQIHVNLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "length": 898, "header": "tr|A0A9J7H0F6-1|A0A9J7H0F6_CRIGR Computationally mapped isoform of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbpl6 PE=3 SV=1 CANONICAL=A0A9J7H2L9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H195-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9/entry#A0A9J7H195-1", "sequence": { "sequence": "MSSDEKGISPAHKTSTPTHRSASSSTSSQRESRQSIHVLERTASSGTEPSVSRQLLEPEPIPLSKEADSWEIIEGLKIGQTNVQKPDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPATSTAESSPAANVSVVDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHNKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEASEQIHVNLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "length": 903, "header": "tr|A0A9J7H195-1|A0A9J7H195_CRIGR Computationally mapped isoform of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbpl6 PE=3 SV=1 CANONICAL=A0A9J7H2L9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9/entry#A0A9J7H2L9-1", "sequence": { "sequence": "MSSDEKGISPAHKTSTPTHRSASSSTSSQRESRQSIHVLERTASSGTEPSVSRQLLEPEPIPLSKEADSWEIIEGLKIGQTNVQKPDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPATSTAESSPAANVSVVDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQEGPPAKGQFNTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHNKGHSTQMARLRQSLSQSEGASKSWALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEASEQIHVNLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "length": 967, "header": "tr|A0A9J7H2L9-1|A0A9J7H2L9_CRIGR Isoform 1 of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbpl6 PE=3 SV=1 CANONICAL=A0A9J7H2L9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JZQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9/entry#A0A9J7JZQ2-1", "sequence": { "sequence": "MSSDEKGISPAHKTSTPTHRSASSSTSSQRESRQSIHVLERTASSGTEPSVSRQLLEPEPIPLSKEADSWEIIEGLKIGQTNVQKPDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPATSTAESSPAANVSVVDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQEGPPAKGQFNTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHNKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEASEQIHVNLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "length": 959, "header": "tr|A0A9J7JZQ2-1|A0A9J7H2L9_CRIGR Computationally mapped isoform of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbpl6 PE=3 SV=1 CANONICAL=A0A9J7H2L9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K936-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9/entry#A0A9J7K936-1", "sequence": { "sequence": "MSSDEKGISPAHKTSTPTHRSASSSTSSQRESRQSIHVLERTASSGTEPSVSRQLLEPEPIPLSKEADSWEIIEGLKIGQTNVQKPDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPATSTAESSPAANVSVVDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQEGPPAKGQFNTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHNKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEASEQIHVNLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "length": 928, "header": "tr|A0A9J7K936-1|A0A9J7H2L9_CRIGR Computationally mapped isoform of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbpl6 PE=3 SV=1 CANONICAL=A0A9J7H2L9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9/entry#A0A9J7KAK2-1", "sequence": { "sequence": "MSSDEKGISPAHKTSTPTHRSASSSTSSQRESRQSIHVLERTASSGTEPSVSRQLLEPEPIPLSKEADSWEIIEGLKIGQTNVQKPDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPATSTAESSPAANVSVVDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHNKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEASEQIHVNLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "length": 934, "header": "tr|A0A9J7KAK2-1|A0A9J7H2L9_CRIGR Computationally mapped isoform of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbpl6 PE=3 SV=1 CANONICAL=A0A9J7H2L9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JZQ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZQ2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JZQ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZQ2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765045", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765045", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2L9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2L9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2L9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9" } ], "pmid": "" }, { "name": "perinuclear endoplasmic reticulum", "id": "GO:0097038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097038", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2L9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2L9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "bile acid biosynthetic process", "id": "GO:0006699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006699", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2L9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2L9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9" } ], "pmid": "" }, { "name": "sterol transfer activity", "id": "GO:0120015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120015", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2L9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" }, { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 563, "end_pos": 565, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 747, "end_pos": 749, "annotation": "n_glycosylation_sequon" }, { "start_pos": 946, "end_pos": 948, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H2L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2L9" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 181, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 212, "end_pos": 214 }, { "start_pos": 293, "end_pos": 295 }, { "start_pos": 339, "end_pos": 341 }, { "start_pos": 515, "end_pos": 517 }, { "start_pos": 558, "end_pos": 560 }, { "start_pos": 563, "end_pos": 565 }, { "start_pos": 569, "end_pos": 571 }, { "start_pos": 747, "end_pos": 749 }, { "start_pos": 946, "end_pos": 948 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H2P3-1", "uniprot_ac": "A0A9J7H2P3", "uniprot_id": "A0A9J7H2P3_CRIGR", "mass": { "chemical_mass": 69511.0, "monoisotopic_mass": 69511.0 }, "refseq": { "ac": "XP_035303006", "name": "potassium voltage-gated channel subfamily C member 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303006" }, "gene_names": [ { "name": "Kcnc1", "type": "recommended", "evidence": [ { "id": "A0A9J7H2P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P3" } ] }, { "name": "Kcnc1", "type": "synonym", "evidence": [ { "id": "XP_035303006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303006" } ] } ], "protein_names": [ { "name": "Potassium voltage-gated channel subfamily C member 1 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H2P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P3/entry#names_and_taxonomy" } ] }, { "name": "potassium voltage-gated channel subfamily C member 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035303006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303006" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303006", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303006" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Kcnc1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P3", "locus": {} } ], "crossref": [ { "id": "A0A9J7H2P3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H2P3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18414", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18414", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100763523", "url": "https://www.ncbi.nlm.nih.gov/gene/100763523", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763523", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763523", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H2P3", "url": "https://www.orthodb.org/?gene=A0A9J7H2P3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537:SF87", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537:SF87", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303006", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303006", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H2P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEALRLSLTATGCASLRIPGVLGTEAEPSPGLEAVNVGSHGGGGGGEGKIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRADSKLNGEVAKAALANEDCPHIDQALTPDEGLPFTRSGTRERYGPCFLLSTGEYACPPGGGMRKDLCKESPVIAKYMPTEAVRVT", "length": 625, "header": "tr|A0A9J7H2P3-1|A0A9J7H2P3_CRIGR Isoform 1 of Potassium voltage-gated channel subfamily C member 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Kcnc1 PE=4 SV=1 CANONICAL=A0A9J7H2P3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H2P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P3/entry#A0A9J7H2P3-1", "sequence": { "sequence": 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"A0A9J7F3R3-1", "A0A9J7F5B0-1", "A0A8C2LDE5-1", "A0A9J7JB60-1", "A0A9J7F927-1", "A0A9J7F8V5-1", "A0A9J7F8T0-1", "A0A9J7FBT0-1", "A0A9J7FD79-1", "A0A9J7FLY5-1", "A0A9J7K2Q7-1", "A0A3L7I1R2-1", "A0A9J7FYY3-1", "A0A9J7GBI2-1", "A0A9J7FN68-1", "A0A9J7FNF0-1", "A0A9J7FS53-1", "A0A9J7FUL0-1", "A0A9J7FVR6-1", "A0A9J7FZH7-1", "A0A9J7FZW1-1", "A0A9J7G1H0-1", "A0A9J7G5F3-1", "A0A9J7G5N9-1", "A0A8C2LFT9-1", "A0A9J7G9D1-1", "A0A8C2MB66-1", "A0A9J7GD76-1", "A0A8C2LQS5-1", "A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GT89-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JIF8-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7F9C4-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A8C2M7I3-1", "A0A8C2MBI9-1", "A0A9J7JQZ1-1", "A0A8C2N3I1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7GBL6-1", "A0A9J7H8W5-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7H540-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H949-1", "A0A9J7GQY0-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] } ] }, { "uniprot_ac": "A0A8C2M3Y9", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] } ] }, { "uniprot_ac": "A0A8C2M497", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] } ] }, { "uniprot_ac": "A0A8C2QPB0", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] } ] }, { "uniprot_ac": "A0A9J7EUQ5", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] } ] }, { "uniprot_ac": "A0A9J7EXX8", "gene_name": "LOC113832238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] } ] }, { "uniprot_ac": "A0A9J7F0J6", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] } ] }, { "uniprot_ac": "A0A9J7F1D2", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1D2" } ] } ] }, { "uniprot_ac": "A0A9J7F2F1", "gene_name": "Prkcd", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F821", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] } ] }, { "uniprot_ac": "A0A9J7F8T0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed 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}, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] } ] }, { "uniprot_ac": "A0A9J7G8N4", "gene_name": "Sgk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] } ] }, { "uniprot_ac": "A0A9J7G969", "gene_name": "LOC100754771", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] } ] }, { "uniprot_ac": "A0A9J7G9D1", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBI2", "gene_name": "LOC100771767", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] } ] }, { "uniprot_ac": "A0A9J7GBL6", "gene_name": "Ttbk2", 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP 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{ "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] } ] }, { "uniprot_ac": "A0A9J7GJE4", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] } ] }, { "uniprot_ac": "A0A9J7GK55", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] } ] }, { "uniprot_ac": "A0A9J7GLT3", "gene_name": "LOC113838166", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] } ] }, { "uniprot_ac": "A0A9J7GMF3", "gene_name": "LOC103158537", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] } ] }, { "uniprot_ac": "A0A9J7GMK5", "gene_name": "Sbk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] } ] }, { "uniprot_ac": "A0A9J7GP29", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] } ] }, { "uniprot_ac": "A0A9J7GQ42", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] } ] }, { "uniprot_ac": "A0A9J7GQY0", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] } ] }, { "uniprot_ac": "A0A9J7GR05", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] } ] }, { "uniprot_ac": "A0A9J7GR29", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] } ] }, { "uniprot_ac": "A0A9J7GRB5", "gene_name": "LOC113838167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRB5" } ] } ] }, { "uniprot_ac": "A0A9J7GRC1", "gene_name": "LOC100764806", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRC1" } ] } ] }, { "uniprot_ac": "A0A9J7GT89", "gene_name": "LOC100774420", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] } ] }, { "uniprot_ac": "A0A9J7GTU0", "gene_name": "LOC100757707", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTU0" } ] } ] }, { "uniprot_ac": "A0A9J7GVC9", "gene_name": "LOC100759146", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVC9" } ] } ] }, { "uniprot_ac": "A0A9J7GX76", "gene_name": "Dapk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GX76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GX76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX76" } ] } ] }, { "uniprot_ac": "A0A9J7GY39", "gene_name": "Akt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] } ] }, { "uniprot_ac": "A0A9J7GZH5", "gene_name": "Ripk4", "activity": [ { "ec_number": "2.7.11.1", "activity": 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"https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302196", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302196" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2R9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2R9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zdhhc12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2R9", "locus": {} } ], "crossref": [ { "id": "A0A9J7H2R9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H2R9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100769641", "url": "https://www.ncbi.nlm.nih.gov/gene/100769641", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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"MRSHQSPRCRSPSAPRPLLPRASSGWAGEGAKAMALWALLSPGVLVRTGHTVLTWGITLVLFLHDTELRQWEEQGELFLPLTFLLLVLGSLLLYLAVSLMDPGYVTAQPQSQEEPKEEQTAMVPQAIPLRRCRYCLVLVGDVHILLWKEPGPSSESLPWRPSTLALPLLQEGLPNLGPDCGLQSSQNALGEPALSLDSPLCPQQPLRARHCRDCRRCVRRYDHHCPWMENCVGERNHPLFVAYLALQLVVLLWGLYLAWSGLRFFQPWGLWLRSTGLLFATFLLLSFFSLVVSLLLASHLYLVASNTTTWEFISSHRIAYLRQRTSNPFDRGLTRNLAHFFCGWPSGPWETLWAEEEEEGSSQAV", "length": 365, "header": "tr|A0A9J7H2R9-1|A0A9J7H2R9_CRIGR Isoform 1 of Palmitoyltransferase OS=Cricetulus griseus OX=10029 GN=Zdhhc12 PE=3 SV=1 CANONICAL=A0A9J7H2R9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H2R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2R9/entry#A0A9J7H2R9-1", "sequence": { "sequence": 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"length": 300, "header": "tr|A0A9J7JSY9-1|A0A9J7H2R9_CRIGR Computationally mapped isoform of Palmitoyltransferase OS=Cricetulus griseus OX=10029 GN=Zdhhc12 PE=3 SV=1 CANONICAL=A0A9J7H2R9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JSY9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSY9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769641", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769641", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2R9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2R9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2R9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2R9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2R9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2R9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2R9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2R9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "L-cysteinyl-[protein] + hexadecanoyl-CoA = 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"MQLGLLVPILFWISGCSTAQDAITGPSMVRGQERGSLTVRCRYKSKWKDYKKYWCQGADWRTCETLVKTDASEKLVKKNRVSIRDNQTDLIFTVTLEDLRISDAGVYWCGIDRVGYDHMFKVNVNIDPVLTTLPTTSTTTMFTESGAVNGTSSFPPMSSPYSTLSDDGGDSDGGSGGSGLLDLSVLLPVISAVLLLLLLVASLFAWRMVRRQNKAAGPHSEQVSSLEGDVCYANLSLQQPRPSHGSSQKKGSSMSSSGKAHQEEVEYVTMAPFPREEISYAALTLAALGQEPIYNNTGSSLVTHIPSTTFEESTQYCSIKRP", "length": 322, "header": "tr|A0A9J7K7L3-1|A0A9J7H2W2_CRIGR Computationally mapped isoform of CMRF35-like molecule 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Cd300lf PE=3 SV=1 CANONICAL=A0A9J7H2W2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H2W6-1", "uniprot_ac": "A0A9J7H2W6", "uniprot_id": "A0A9J7H2W6_CRIGR", "mass": { "chemical_mass": 72779.0, "monoisotopic_mass": 72779.0 }, "refseq": { "ac": "XP_035302724", "name": "sodium/nucleoside cotransporter 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302724" }, "gene_names": [ { "name": "Slc28a2", "type": "recommended", "evidence": [ { "id": "A0A9J7H2W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2W6" } ] }, { "name": "Slc28a2", "type": "synonym", "evidence": [ { "id": "XP_035302724", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302724" } ] } ], "protein_names": [ { "name": "Sodium/nucleoside cotransporter", "type": "recommended", "evidence": [ { "id": "A0A9J7H2W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2W6/entry#names_and_taxonomy" } ] }, { "name": "sodium/nucleoside cotransporter 2", "type": "synonym", "evidence": [ { "id": "XP_035302724", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302724" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302724", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302724" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H2W6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2W6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc28a2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2W6", "locus": {} } ], "crossref": [ { "id": "A0A9J7H2W6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H2W6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100774101", "url": "https://www.ncbi.nlm.nih.gov/gene/100774101", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR10590", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10590", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10590:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10590:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302724", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302724", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": 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"tr|A0A9J7H2W6-1|A0A9J7H2W6_CRIGR Isoform 1 of Sodium/nucleoside cotransporter OS=Cricetulus griseus OX=10029 GN=Slc28a2 PE=3 SV=1 CANONICAL=A0A9J7H2W6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H2W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2W6/entry#A0A9J7H2W6-1", "sequence": { "sequence": "MEKEEGRESASQATVENGIENLGLELMERGDPERNKKIDSTQEHSLKDGQGPSSFWRRNLNPFIKARSFFKRHAVLFKKILLGLLCAAYAAYFLAACILNFQRALALFVITCLVIFILACHFLKKIVGKKLISCLKPFRNPRLIRWVKWVFAGASVVGLILWLALDTAQRPEQLISFAGICMFILILFVFSKHHSAVCWRTVFWGLGLQFVFGILVIRTEPGFNAFQWLGDQIQIFLAYTVDGSSFVFGDALVQNVFAFQSLPIIIFFGCVMSILYYLGLVQWVIQKIAWFLQITMGTTAAETLAVAGNIFVGMTEAPLLIRPYLADMTLSEIHAVMTGGFATIAGTVLGAFISFGIDASSLISASVMAAPCALALSKLVYPEVEESKFKSKEGVKLPDREERNILEAASNGATDAIALVANVAANLIAFLAVLAFVNSTLSWLGEMVDIHGLSFQVICSYVLRPMVFMMGVEWADCPLVAEIVGVKFFINEFVAYQQLSQYKNKRLSGVEEWINGEKQWISVKAEIIATFSLCGFANLTSIGITLGGLTSMMPQRKSDLCKLVVRALFTGACVSFISACMAGILYVPRGAEADCVSFLSTGFTNRTYETYVCCRELFHNTWLNGTNMPSFSGPWEDKEFSAMNLATCCDLYNSTVCV", "length": 658, "header": 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304031", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304031" } ] }, { "annotation": "Catalyzes the reversible hydration of carbon dioxide into bicarbonate and protons and thus is essential to maintaining intracellular and extracellular pH. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. 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} ] }, { "uniprot_ac": "A0A8C2QGQ6", "gene_name": "Ca3", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A8C2QGQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGQ6" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A8C2QGQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGQ6" } ] } ] }, { "uniprot_ac": "A0A9J7FFR7", "gene_name": "Ca9", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A9J7FFR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFR7" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A9J7FFR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFR7" } ] } ] }, { "uniprot_ac": "A0A9J7FIZ4", "gene_name": "Ca7", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) 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}, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A9J7GQZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQZ7" } ] } ] }, { "uniprot_ac": "A0A9J7H322", "gene_name": "Ca4", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A9J7H322", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H322" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A9J7H322", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H322" } ] } ] }, { "uniprot_ac": "A0A9J7JFI9", "gene_name": "Ca12", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A9J7JFI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFI9" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A9J7JFI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFI9" } ] } ] }, { "uniprot_ac": "A0A9J7JN17", "gene_name": "Ca5a", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A9J7JN17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JN17" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A9J7JN17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JN17" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H322", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H322" }, { "id": "PS51144", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51144" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-carbonic anhydrase", "eco_id": "ECO_0000259", "start_pos": 122, "end_pos": 382, "start_aa": "Ala", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.2.1.1", "ec_name": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "4.2.1.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.1" }, { "id": "4.2.1.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.2.1.1" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 293, "end_pos": 295 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H3T0-1", "uniprot_ac": "A0A9J7H3T0", "uniprot_id": "A0A9J7H3T0_CRIGR", "mass": { "chemical_mass": 133155.0, "monoisotopic_mass": 133155.0 }, "refseq": { "ac": "XP_035303661", "name": "myelin transcription factor 1-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303661" }, "gene_names": [ { "name": "Myt1l", "type": "recommended", "evidence": [ { "id": "A0A9J7H3T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0" } ] }, { "name": "Myt1l", "type": "synonym", "evidence": [ { "id": "XP_035303661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303661" } ] } ], "protein_names": [ { "name": "Myelin transcription factor 1-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7H3T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0/entry#names_and_taxonomy" } ] }, { "name": "myelin transcription factor 1-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035303661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303661" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303661" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3T0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Myt1l", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0", "locus": {} } ], "crossref": [ { "id": "A0A9J7H3T0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H3T0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100750480", "url": "https://www.ncbi.nlm.nih.gov/gene/100750480", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013681", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013681", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750480", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750480", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ECYESDA", "url": "https://omabrowser.org/oma/group/ECYESDA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H3T0", "url": "https://www.orthodb.org/?gene=A0A9J7H3T0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10816", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10816", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10816:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10816:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303661", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H325", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H325", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H325-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H325-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3T0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4H9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4H9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K0I3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K0I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0I3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K838", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K838", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K838-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K838-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KA05", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KA05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KA05-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KA05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVDAEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECFESDGTEDMDDKEEDEEEEFSEDNDDQGDEDDEDEEVDREDEEEIEEEDDDDDDDEDGDDVEEEEEEEEEEEEEEEEEEENEDHQMSCTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENISDRSYAEGMSQQDSRNMNYVMLGKPMNNGLMDKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQDRSQPPNMSVRQHVRQEDDFPGRTPDRSYSDMMNLMRLEEQLSPRSRTFSSCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMDAGRRDNLRSYEDQSPRQLAGEDRKSKSSDSHVKKPYYGKDPSRTEKRESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHENVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSNQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKNASPSSSTTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCTARNPDMEVDENGTLDLSMNKQRPRDSCCPVLTPLEPMSPQQQAVMSSRCFQLSEGDCWDLPVDYTKMKPRRVDEDDPKEITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQVTITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV", "length": 1189, "header": "tr|A0A9J7H3T0-1|A0A9J7H3T0_CRIGR Isoform 1 of Myelin transcription factor 1-like protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Myt1l PE=3 SV=1 CANONICAL=A0A9J7H3T0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H325-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0/entry#A0A9J7H325-1", "sequence": { "sequence": "MDVDAEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECFESDGTEDMDDKEEDEEEEFSEDNDDQGDEDDEDEEVDREDEEEIEEEDDDDDDDEDGDDVEEEEEEEEEEEEEEEEEEENEDHQMSCTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENISDRSYAEGMSQQDSRNMNYVMLGKPMNNGLMDKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQDRSQPPNMSVRQHVRQEDDFPGRTPDRSYSDMMNLMRLEEQLSPRSRTFSSCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMDAGRRDNLRSYEDQSPRQLAGEDRKSKSSDSHVKKPYYVLAMHENVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSNQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKNASPSSSTTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCTARNPDMEVDENGTLDLSMNKQRPRDSCCPVLTPLEPMSPQQQAVMSSRCFQLSEGDCWDLPVDYTKMKPRRVDEDDPKEITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV", "length": 1140, "header": "tr|A0A9J7H325-1|A0A9J7H3T0_CRIGR Computationally mapped isoform of Myelin transcription factor 1-like protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Myt1l PE=3 SV=1 CANONICAL=A0A9J7H3T0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H3T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0/entry#A0A9J7H3T0-1", "sequence": { "sequence": "MDVDAEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECFESDGTEDMDDKEEDEEEEFSEDNDDQGDEDDEDEEVDREDEEEIEEEDDDDDDDEDGDDVEEEEEEEEEEEEEEEEEEENEDHQMSCTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENISDRSYAEGMSQQDSRNMNYVMLGKPMNNGLMDKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQDRSQPPNMSVRQHVRQEDDFPGRTPDRSYSDMMNLMRLEEQLSPRSRTFSSCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMDAGRRDNLRSYEDQSPRQLAGEDRKSKSSDSHVKKPYYGKDPSRTEKRESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHENVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSNQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKNASPSSSTTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCTARNPDMEVDENGTLDLSMNKQRPRDSCCPVLTPLEPMSPQQQAVMSSRCFQLSEGDCWDLPVDYTKMKPRRVDEDDPKEITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQVTITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV", "length": 1189, "header": "tr|A0A9J7H3T0-1|A0A9J7H3T0_CRIGR Isoform 1 of Myelin transcription factor 1-like protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Myt1l PE=3 SV=1 CANONICAL=A0A9J7H3T0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H4H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0/entry#A0A9J7H4H9-1", "sequence": { "sequence": "MDVDAEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECFESDGTEDMDDKEEDEEEEFSEDNDDQGDEDDEDEEVDREDEEEIEEEDDDDDDDEDGDDVEEEEEEEEEEEEEEEEEEENEDHQMSCTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENISDRSYAEGMSQQDSRNMNYVMLGKPMNNGLMDKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQDRSQPPNMSVRQHVRQEDDFPGRTPDRSYSDMMNLMRLEEQLSPRSRTFSSCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMDAGRRDNLRSYEDQSPRQLAGEDRKSKSSDSHVKKPYYDPSRTEKRESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHENVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSNQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKNASPSSSTTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCTARNPDMEVDENGTLDLSMNKQRPRDSCCPVLTPLEPMSPQQQAVMSSRCFQLSEGDCWDLPVDYTKMKPRRVDEDDPKEITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV", "length": 1185, "header": "tr|A0A9J7H4H9-1|A0A9J7H4H9_CRIGR Computationally mapped isoform of Myelin transcription factor 1-like protein isoform X3 OS=Cricetulus griseus OX=10029 GN=Myt1l PE=3 SV=1 CANONICAL=A0A9J7H3T0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K0I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0/entry#A0A9J7K0I3-1", "sequence": { "sequence": "MDVDAEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECFESDGTEDMDDKEEDEEEEFSEDNDDQGDEDDEDEEVDREDEEEIEEEDDDDDDDEDGDDVEEEEEEEEEEEEEEEEEEENDHQMSCTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENISDRSYAEGMSQQDSRNMNYVMLGKPMNNGLMDKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQDRSQPPNMSVRQHVRQEDDFPGRTPDRSYSDMMNLMRLEEQLSPRSRTFSSCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMDAGRRDNLRSYEDQSPRQLAGEDRKSKSSDSHVKKPYYDPSRTEKRESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHENVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSNQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKNASPSSSTTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCTARNPDMEVDENGTLDLSMNKQRPRDSCCPVLTPLEPMSPQQQAVMSSRCFQLSEGDCWDLPVDYTKMKPRRVDEDDPKEITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV", "length": 1184, "header": "tr|A0A9J7K0I3-1|A0A9J7H3T0_CRIGR Computationally mapped isoform of Myelin transcription factor 1-like protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Myt1l PE=3 SV=1 CANONICAL=A0A9J7H3T0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K838-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0/entry#A0A9J7K838-1", "sequence": { "sequence": "MDVDAEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECFESDGTEDMDDKEEDEEEEFSEDNDDQGDEDDEDEEVDREDEEEIEEEDDDDDDDEDGDDVEEEEEEEEEEEEEEEEEEENEDHQMSCTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENISDRSYAEGMSQQDSRNMNYVMLGKPMNNGLMDKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQDRSQPPNMSVRQHVRQEDDFPGRTPDRSYSDMMNLMRLEEQLSPRSRTFSSCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMDAGRRDNLRSYEDQSPRQLAGEDRKSKSSDSHVKKPYYGKDPSRTEKRESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHENVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSNQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKNASPSSSTTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCTARNPDMEVDENGTLDLSMNKQRPRDSCCPVLTPLEPMSPQQQAVMSSRCFQLSEGDCWDLPVDYTKMKPRRVDEDDPKEITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV", "length": 1187, "header": "tr|A0A9J7K838-1|A0A9J7H3T0_CRIGR Computationally mapped isoform of Myelin transcription factor 1-like protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Myt1l PE=3 SV=1 CANONICAL=A0A9J7H3T0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KA05-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0/entry#A0A9J7KA05-1", "sequence": { "sequence": "MDVDAEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECFESDGTEDMDDKEEDEEEEFSEDNDDQGDEDDEDEEVDREDEEEIEEEDDDDDDDEDGDDVEEEEEEEEEEEEEEEEEEENEDHQMSCTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENISDRSYAEGMSQQDSRNMNYVMLGKPMNNGLMDKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQDRSQPPNMSVRQHVRQEDDFPGRTPDRSYSDMMNLMRLEEQLSPRSRTFSSCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMDAGRRDNLRSYEDQSPRQLAGEDRKSKSSDSHVKKPYYDPSRTEKRESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHENVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSNQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKNASPSSSTTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCTARNPDMEVDENGTLDLSMNKQRPRDSCCPVLTPLEPMSPQQQAVMSSRCFQLSEGDCWDLPVDYTKMKPRRVDEDDPKEITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMEDGVWWGQ", "length": 1147, "header": "tr|A0A9J7KA05-1|A0A9J7H3T0_CRIGR Computationally mapped isoform of Myelin transcription factor 1-like protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Myt1l PE=3 SV=1 CANONICAL=A0A9J7H3T0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0/entry#A0A9J7KBG9-1", "sequence": { "sequence": "MDVDAEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECFESDGTEDMDDKEEDEEEEFSEDNDDQGDEDDEDEEVDREDEEEIEEEDDDDDDDEDGDDVEEEEEEEEEEEEEEEEEEENEDHQMSCTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENISDRSYAEGMSQQDSRNMNYVMLGKPMNNGLMDKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQDRSQPPNMSVRQHVRQEDDFPGRTPDRSYSDMMNLMRLEEQLSPRSRTFSSCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMDAGRRDNLRSYEDQSPRQLAGEDRKSKSSDSHVKKPYYDPSRTEKRESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHENVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSNQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKNASPSSSTTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCTARNPDMEVDENGTLDLSMNKQRPRDSCCPVLTPLEPMSPQQQAVMSSRCFQLSEGDCWDLPVDYTKMKPRRVDEDDPKEITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQVTITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMEDGVWWGQ", "length": 1149, "header": "tr|A0A9J7KBG9-1|A0A9J7H3T0_CRIGR Computationally mapped isoform of Myelin transcription factor 1-like protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Myt1l PE=3 SV=1 CANONICAL=A0A9J7H3T0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1010, "start_aa": "Thr", "end_pos": 1010, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1010", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 33, "start_aa": "Thr", "end_pos": 33, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr33", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 509, "start_aa": "Thr", "end_pos": 509, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr509", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 553, "start_aa": "Thr", "end_pos": 553, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr553", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 908, "start_aa": "Thr", "end_pos": 908, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr908", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K0I3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0I3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K0I3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0I3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750480", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750480", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P70475-1", "protein_name": "Myelin transcription factor 1-like protein", "gene_name": "Myt1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVDAEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECYESDGTEDMDDKEEDDDEEFSEDNDEQGDDDDEDEVDREDEEEIEEEDDEDDEDDDDGDDVEEEEDDDDEEEEEEEEEEENEDHQMSCTRIMQDPEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENISDRSYAEGMSQQDSRNMNYVMLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQDRSQPPNMSVRQHVRQEDDFPGRTPDRSYSDMMNLMRLEEQLSPRSRTFSSCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMDAGRRDNLRSYEDQSPRQLAGEDRKSKSSDSHVKKPYYDPSRTEKRESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHENVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSNQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKNASPSSSTTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCTARNPDMEVDENGTLDLSMNKQRPRDSCCPVLTPLEPMSPQQQAVMSSRCFQLSEGDCWDLPVDYTKMKPRRVDEEDPKEITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQVTITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV", "length": 1187 }, "evidence": [ { "id": "A0A9J7H3T0", "url": "https://omabrowser.org/oma/group/A0A9J7H3T0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P97500-1", "protein_name": "Myelin transcription factor 1-like protein", "gene_name": "Myt1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDVDSEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECYESDGTEDMDDKEEDDDEEFSEDNDEQGDDDDEDEVDREDEEEIEEEDDEEDDDDEDGDDVEEEEEDDDEEEEEEEEEEENEDHQMSCTRIMQDTDKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENISDRSYAEGMSQQDSRNMNYVMLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQDRSQPPNMSVRQHVRQEDDFPGRTPDRSYSDMMNLMRLEEQLSPRSRTFSSCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMDAGRRDNLRSYEDQSPRQLAGEDRKSKSSDSHVKKPYYGKDPSRTEKRESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHENVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSNQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKNASPSSSTTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCTARNPDMEVDENGTLDLSMNKQRPRDSCCPVLTPLEPMSPQQQAVMSSRCFQLSEGDCWDLPVDYTKMKPRRVDEDEPKEITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV", "length": 1187 }, "evidence": [ { "id": "A0A9J7H3T0", "url": "https://omabrowser.org/oma/group/A0A9J7H3T0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UL68-1", "protein_name": "Myelin transcription factor 1-like protein", "gene_name": "MYT1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYVMLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQHVRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKPKSSDSHVKKPYYGKDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRPRDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV", "length": 1186 }, "evidence": [ { "id": "A0A9J7H3T0", "url": "https://omabrowser.org/oma/group/A0A9J7H3T0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3T0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3T0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3T0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3T0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3T0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1077, "end_pos": 1079, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1117, "end_pos": 1119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1126, "end_pos": 1128, "annotation": "n_glycosylation_sequon" }, { 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"structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H3T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T0" }, { "id": "PF08474", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08474" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myelin transcription factor 1", "eco_id": "ECO_0000259", "start_pos": 622, "end_pos": 873, "start_aa": "Tyr", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 33, 509, 553, 908, 1010 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1077, "end_pos": 1079 }, { "start_pos": 1117, "end_pos": 1119 }, { "start_pos": 1126, "end_pos": 1128 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 280, "end_pos": 282 }, { "start_pos": 355, "end_pos": 357 }, { "start_pos": 431, "end_pos": 433 }, { "start_pos": 654, "end_pos": 656 }, { "start_pos": 685, "end_pos": 687 }, { "start_pos": 703, "end_pos": 705 }, { "start_pos": 739, "end_pos": 741 }, { "start_pos": 750, "end_pos": 752 }, { "start_pos": 771, "end_pos": 773 }, { "start_pos": 992, "end_pos": 994 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H337-1", "uniprot_ac": "A0A9J7H337", "uniprot_id": "A0A9J7H337_CRIGR", "mass": { "chemical_mass": 50308.0, "monoisotopic_mass": 50308.0 }, "refseq": { "ac": "XP_035304047", "name": "RUN domain-containing protein 3A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304047" }, "gene_names": [ { "name": "Rundc3a", "type": "recommended", "evidence": [ { "id": "A0A9J7H337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H337" } ] }, { "name": "Rundc3a", "type": "synonym", "evidence": [ { "id": "XP_035304047", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304047" } ] } ], "protein_names": [ { "name": "RUN domain-containing protein 3A", "type": "recommended", "evidence": [ { "id": "A0A9J7H337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H337/entry#names_and_taxonomy" } ] }, { "name": "RUN domain-containing protein 3A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035304047", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304047" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304047", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304047" } ] }, { "annotation": "May act as an effector of RAP2A in neuronal cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H337", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H337#function" }, { "database": "UniProtKB", "id": "ARBA00056205", "url": "https://www.uniprot.org/uniprotkb/ARBA00056205#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H337", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H337" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rundc3a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H337", "locus": {} } ], "crossref": [ { "id": "A0A9J7H337", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H337", "database": "AlphaFoldDB", "categories": [] }, { "id": "100755469", "url": "https://www.ncbi.nlm.nih.gov/gene/100755469", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755469", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755469", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H337", "url": "https://www.orthodb.org/?gene=A0A9J7H337", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46251", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46251", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46251:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46251:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304047", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304047", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H337", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H337", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H337-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H337-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALGLPSKKASSRNVIVERRNLITVCSSSLLDPLSLPPPRFSVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHRFKACAPAGPASWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENISTARAKGRAWIRVALMEKRMSEYITTALRDNRTTRRFYDSGAIMLREEATVLTGMLIGLSAIDFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPLVTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQNQREKRELEGVILELQEQLTGLIPGDHAPLAQGSKEFTTPLVNQWPSLSTLNRPEGASNSKLYRRHSFMSTEPLSAEASLSSDSQRLGEGKRDEEPWGPIGKDPTPSMLGLCGSLASIPSCKSLASFKSNECLVSDSPEGSPALSPS", "length": 450, "header": "tr|A0A9J7H337-1|A0A9J7H337_CRIGR Isoform 1 of RUN domain-containing protein 3A OS=Cricetulus griseus OX=10029 GN=Rundc3a PE=3 SV=1 CANONICAL=A0A9J7H337-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H337-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H337/entry#A0A9J7H337-1", "sequence": { "sequence": "MALGLPSKKASSRNVIVERRNLITVCSSSLLDPLSLPPPRFSVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHRFKACAPAGPASWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENISTARAKGRAWIRVALMEKRMSEYITTALRDNRTTRRFYDSGAIMLREEATVLTGMLIGLSAIDFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPLVTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQNQREKRELEGVILELQEQLTGLIPGDHAPLAQGSKEFTTPLVNQWPSLSTLNRPEGASNSKLYRRHSFMSTEPLSAEASLSSDSQRLGEGKRDEEPWGPIGKDPTPSMLGLCGSLASIPSCKSLASFKSNECLVSDSPEGSPALSPS", "length": 450, "header": "tr|A0A9J7H337-1|A0A9J7H337_CRIGR Isoform 1 of RUN domain-containing protein 3A OS=Cricetulus griseus OX=10029 GN=Rundc3a PE=3 SV=1 CANONICAL=A0A9J7H337-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 408, "start_aa": "Thr", "end_pos": 408, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr408", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H337", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H337" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H337", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H337" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755469", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755469", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H337" }, { "id": "PS50826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 193, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 408 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 153, "end_pos": 155 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H350-1", "uniprot_ac": "A0A9J7H350", "uniprot_id": "A0A9J7H350_CRIGR", "mass": { "chemical_mass": 337558.0, "monoisotopic_mass": 337558.0 }, "refseq": { "ac": "XP_035304062", "name": "LOW QUALITY PROTEIN: myosin XVB isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304062" }, "gene_names": [ { "name": "Myo15b", "type": "recommended", "evidence": [ { "id": "A0A9J7H350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H350" } ] }, { "name": "Myo15b", "type": "synonym", "evidence": [ { "id": "XP_035304062", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304062" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: myosin XVB isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035304062", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304062" }, { "id": "A0A9J7H350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H350/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304062" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H350", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H350" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Myo15b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H350", "locus": {} } ], "crossref": [ { "id": "cd14473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14896", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14896", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755327", "url": "https://www.ncbi.nlm.nih.gov/gene/100755327", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755327", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755327", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H350", "url": "https://www.orthodb.org/?gene=A0A9J7H350", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22692", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22692", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22692:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22692:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00784", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00784", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26570", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26570", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304062", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H350", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H350", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H350-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H350-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGSKGKAPQRRAQPRRPASAEQESGSASADGAPSRDRRLARGKAHKARPAKEPDATEDEGTSGGRRKSTEETRERQGSSQRPRGRRPTESREPGDSRGELREEQRLPKRGRRRRGKERGPSAPGRDADTSGGDGGSSCLDSEHHEALDSSSQGGGASERPTKTEPGDTGSEGALIRSPGATGSSHQDNGGHALGLRSGEGPSGSGPRGAGDDSRTDADSSSGWAGHGRRPRKTPGASSSIPESQETELGGEAVASGSLGSSCANAPRGPLGPLGSKAIADVSDSDVGAQPKAELLGTEPETAEAPRAQRLQVGEAAGKVQVVKSDAGARGGAGAGDPAPLAALLVLRKLRARAPAGASPQPAGGLRVGLKARLQRVAQALGLLRWLRLRVQQHRGDARGESPREHKERGRERALEARGGLRGPPRWRAVRLACRAVLRAPPRAPPGGSPSLPQALKSPSSEGASAIEDAAPDPKFAVVFPRIHSAEKESGGGSSGASTDAPTGEGRVSSPAGAAEYREEQGAREEGVVRSHQPPSFSPSAPDGTPPDENRSEAEPDTLEVESRVHWAQGSTPCADPGVGTGTLLPQLTLETRLQQNSPCRSPREQWEPEDDAEAALERALELSLEMPPFPGAKTRSLPEALEDTEDLARLRLVCDSSVLLCLKKRFHLGRIYTFGGPLLLALNPHQPLPLFSPEILASYHPRKAANTTPHIFAVGAAAYRLSQSAGPAPCILLGGHSGSGKTEAAKKIVEFLSSLGQKQAEARGAQLEDILPVLSSFGHAKTILNANGSRFGQELCLCLHHGVNVGASVSHYLLETSRVVFQVRTCLLPTLPQLXKLEGGATALKPHPTLKPVSLPKAQAERSFHVFYELLAGLDPGDRELLSLQGPEAYYYLNQGQTCRLQGKEDAQDFKGLVKALQVLGLCAEELSEVWAVLATILHLGNICFSSSERESQEVAALSSWAEIHLAARLLRVPPERLEGAITKRVLDTPYGRVSRSLPVESAIDARDALAKTLYTRLFNWLLKQINVLLAPPREADSVATITVVDAFGFEALRVNGLEQLCSNLASERLQLFSSQRLLAQEEEECQREMLSWVPIPQPRRESCLDLLAGQPHSLLSILDSQTWLAQATDHTFLHKCHYHHGDHPSYAKPQLPLPIFTVQHYAGTVTYQVHKFINRNRDHLDSAMVEMLGQSQLQLVCSLFQEAEPQAGREEGKPTLASRFQQSLGGLLARLGRSHIYVIHCLNPTPGKLPGLFNVGHMAEQLLQAGILEVIGTRSAHFPVRVPFQLFLTRFRALGSGRQEALSDQERCGAILSQVLGAESPVYHLGNTQVLLQEQGWQQLEQLLGQQRSQALLTLHRGLRACITRQRLRLLPRMQARVRGLQARKRYLQRKSALGQLNTILLVARPLLQRRQRRQQMGSDVHSLETGLLGPGGDTELLSPGVGCWWCGGINSRWISLQFGQSRGPHSGEAWGKLSSMDLGRLEIPAQLAALLETAEGHQAILAGSITESLPPGVPVRPNLTLPPDIDQFPFSSFVSSSFRKPYLPRPGQLLDEPLTRMDGENPQQALEINRVMLRLLGEGSLQSWQEQTMGTYLIRKAQHRPGLRDELFSQLVAQLWHNPDEQQSQRGWALMAALLSSFPPTPALQKPLLKFVSDQGSRGMAALCQHKLLGALEQTQLAPMASRTHPPTQLEWKAGLRQGRMVLDVFTFNEESYFAEVESWTTGEQLAGRILHSRGLEAPPRGWSVSLHSGDAWQDLAGCDFVLDLIGRTEDLGDPAGSHNYPITPLGLAENIPPAPGVQAPSLPPGFPPGPAPTLPSSGPPGEARKPGNMDGFLDYIFEPVLSSGFSDLEHSRALSSRMKGGGSIGPTQPGYPMVYPGMVQAPSYQPAMMPAPVPMMPAMGTVPTIPAMMVPPQPQPLLPSLDSRQLAVQQQNFINQQAMILAQQMTTQAMSMSLEQQNQRRQNQAQASGAPSQTPPPAVAPPPAVAPPSATAPKPKKPPASQEKPESDPEPLDASSRGDTPEEATGRPQRPRSFQQKRDYFQKMGQEPIRVKTVKPPAKVQIPQEETDENEDEEEEEDTAESSPPPPPPVVKKPLKQTKPNSAKDGAEPAEEEKPTPGRAPKVKSSTPQSPPPSRAPTVSSSNSTPQRPQPSREIRNIIRMYQSRPGPVPVPVQPSRPVKPFQKKNDPKDEALAKLGISGTHLPPSAMSPNLGKNSPPAVAPRPKARPQLEPSLSIQEKQGPLRDLFGPCSPNPSTTPAPPSPPPLPLSLPEEPKAHSVGSHALTEPMEDLGISTKLLVPSGSVCFSYASAPWKLFLRKEVFYPRENFSHPYCLNLLCQQIIQDTFTESCIRISQSERQKMKDLLGDLEVGLDSLDSTEDSIKKRIVVAARDNWANYFSRIFPVSGESGSDIQMLGVSHRGLRLLKVTRDPSFHLDRLKTLCSYSFAEVLAVGCSSSSTLELSLKNEQLTLHTAQARAIKAMVEQFLNELKKDSGYVIALRSYITDDHSLLSFHRGDLIKLLPAGILEPGWQFGSVGGHSGLFPADVVQPAAAPDFSFSLGQRNSWHRKSKTGPAHERPTHPRSQEPSEDSEATSFAAYSLFSADSHNYTMQEFALRYFRKPQTLLAQAGRGANDKAEVSLVQYTKDPIQESLLSLSNEDINRKAVAGFKALMQFMGDQPKPRGKDELDLLYELLTLCREDLRDEMYCQVIKQVTGHPQPNHCVLGWNVLSLFTGFFAPSTTLMPYVTKFLQDSSPSQELARSSQENLQRTVKYGGRHKLPPPGEMQAFLKGQAVRSLLIHLPGGVDYRTNVQTFTVAGEVLEELCGQMGITDSQEVQEFALFLIKGEGELVRPLSPHEYLNSAVTDKDMSLHSRRLGWETPLHFDHPTYTETHYGQVLRDYLQGKLMISAQADAQLARLAALQHLRKASKSLPSEQELLVYIPKPLQQQVNIANIRSLVGQELRQMQGYSAQRAQIDFIESTTQLPLFGYTVYVVLRVSKLSLPGPILLGLNRQHLVLMDSSSQRLCCSIPLRDLQRLHLLSPLEDNGAPGLELNYGSADNPHTIWLELPQAQELKHTIVFLLEDSMSSTQWPGLS", "length": 3101, "header": "tr|A0A9J7H350-1|A0A9J7H350_CRIGR Isoform 1 of LOW QUALITY PROTEIN: myosin XVB isoform X2 OS=Cricetulus griseus OX=10029 GN=Myo15b PE=3 SV=1 CANONICAL=A0A9J7H350-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H350-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H350/entry#A0A9J7H350-1", "sequence": { "sequence": 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"length": 3101, "header": "tr|A0A9J7H350-1|A0A9J7H350_CRIGR Isoform 1 of LOW QUALITY PROTEIN: myosin XVB isoform X2 OS=Cricetulus griseus OX=10029 GN=Myo15b PE=3 SV=1 CANONICAL=A0A9J7H350-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1247, "start_aa": "Thr", "end_pos": 1247, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1247", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1644, "start_aa": "Thr", "end_pos": 1644, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1644", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1871, "start_aa": "Thr", "end_pos": 1871, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1871", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2120, "start_aa": "Thr", "end_pos": 2120, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2120", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H350", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H350" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H350", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H350" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755327", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755327", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H350", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H350" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H350", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H350" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H350", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H350" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H350", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H350" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H350", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H350" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1521, "end_pos": 1523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302537" } ] }, { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3A1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3A1#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3A1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3A1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100764870", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3A1", "locus": {} } ], "crossref": [ { "id": "A0A9J7H3A1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H3A1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100764870", "url": "https://www.ncbi.nlm.nih.gov/gene/100764870", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764870", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764870", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H3A1", "url": "https://www.orthodb.org/?gene=A0A9J7H3A1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302537", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H3A1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3A1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTQGNDTKVADFYLLGFGVQHDTQCVLFIVFLIIYVTSMVGNTGMILLINTNSRLQTPMYFFLQHLAFVDICYTSAITPKMLQNFIIEDKSITFKGCLIQLFIYAIFATSDCYLLAVMAVDRYVAICKPLRYPIIMSRQICIQLVAGSYLMGSINSSVHTGFTFSLSFCKSKINHFFCDIPPIVTLSCYNNDTNFMLILIFVGFNLTFTVLVVIFSYIYIMSAILKMSSTAGRKKTFSTCASHLTAVTIFYGTLAYMYLQPHSENSEENMKVASVFYGIVIPMLNPLIYSLRNKEVKDAIKATGKRLFKLDLNY", "length": 314, "header": "tr|A0A9J7H3A1-1|A0A9J7H3A1_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100764870 PE=3 SV=1 CANONICAL=A0A9J7H3A1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H3A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3A1/entry#A0A9J7H3A1-1", "sequence": { "sequence": "MTQGNDTKVADFYLLGFGVQHDTQCVLFIVFLIIYVTSMVGNTGMILLINTNSRLQTPMYFFLQHLAFVDICYTSAITPKMLQNFIIEDKSITFKGCLIQLFIYAIFATSDCYLLAVMAVDRYVAICKPLRYPIIMSRQICIQLVAGSYLMGSINSSVHTGFTFSLSFCKSKINHFFCDIPPIVTLSCYNNDTNFMLILIFVGFNLTFTVLVVIFSYIYIMSAILKMSSTAGRKKTFSTCASHLTAVTIFYGTLAYMYLQPHSENSEENMKVASVFYGIVIPMLNPLIYSLRNKEVKDAIKATGKRLFKLDLNY", "length": 314, "header": "tr|A0A9J7H3A1-1|A0A9J7H3A1_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100764870 PE=3 SV=1 CANONICAL=A0A9J7H3A1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"uniprot_id": "A0A9J7H3A2_CRIGR", "mass": { "chemical_mass": 131137.0, "monoisotopic_mass": 131137.0 }, "refseq": { "ac": "XP_035300156", "name": "neuronal cell adhesion molecule", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300156" }, "gene_names": [ { "name": "Nrcam", "type": "recommended", "evidence": [ { "id": "A0A9J7H3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3A2" } ] }, { "name": "Nrcam", "type": "synonym", "evidence": [ { "id": "XP_035300156", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300156" } ] } ], "protein_names": [ { "name": "Neuronal cell adhesion molecule", "type": "recommended", "evidence": [ { "id": "A0A9J7H3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3A2/entry#names_and_taxonomy" } ] }, { "name": "Neuronal surface protein Bravo", "type": "synonym", "evidence": [ { "id": "A0A9J7H3A2", "database": "UniProtKB", "url": 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analysis. This record is derived from a genomic sequence (NW_003613674.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035300156", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300156" } ] }, { "annotation": "Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters. Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3A2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3A2#function" }, { "database": "UniProtKB", "id": "ARBA00056038", "url": "https://www.uniprot.org/uniprotkb/ARBA00056038#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3A2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3A2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nrcam", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3A2", "locus": {} } ], "crossref": [ { "id": "A0A9J7H3A2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H3A2", "database": "AlphaFoldDB", "categories": [] }, { "id": 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3A2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3A2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301559", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301559" } ] }, { "annotation": "Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. 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"length": 2424, "header": "tr|A0A9J7H3B2-1|A0A9J7H3B2_CRIGR Isoform 1 of Spectrin alpha chain, erythrocytic 1 OS=Cricetulus griseus OX=10029 GN=LOC100771374 PE=3 SV=1 CANONICAL=A0A9J7H3B2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3B2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3B2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3B2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3B2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771374", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771374", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3B2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3B2" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3B2", "url": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302614" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100764529", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E3", "locus": {} } ], "crossref": [ { "id": "A0A9J7H3E3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H3E3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15226", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15226", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764529", "url": "https://www.ncbi.nlm.nih.gov/gene/100764529", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764529", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764529", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H3E3", "url": "https://www.orthodb.org/?gene=A0A9J7H3E3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302614", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H3E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGGNQSVVSEFILWGLSQSQKLQVLLFVIFLILYFFIVSGNIVIMLLITTDHHLHSPMYFLLANLSFVDMWLSSVTTPKMISDFPRENKTISFEGCMSQIFFAHCIAGVEMVLLVVMAYDRYVAICKPLHYFTIMNLKRCTGLVFISWTTGLIHATSHLVEIVELPFCGPKEIDSFFCDMPLVIKLACLDSHDLDILMNANCGVVAVICFILLLISYTYILTNVLQSSKSGASKALSTCTAHITVVMIFFVPCLFIYVWPLNIIWLDKFLAVFYSVFTPLLNPAIYTLRNKEIKNAMRRFLSNYLFKENP", "length": 311, "header": "tr|A0A9J7H3E3-1|A0A9J7H3E3_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100764529 PE=3 SV=1 CANONICAL=A0A9J7H3E3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H3E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E3/entry#A0A9J7H3E3-1", "sequence": { "sequence": "MDGGNQSVVSEFILWGLSQSQKLQVLLFVIFLILYFFIVSGNIVIMLLITTDHHLHSPMYFLLANLSFVDMWLSSVTTPKMISDFPRENKTISFEGCMSQIFFAHCIAGVEMVLLVVMAYDRYVAICKPLHYFTIMNLKRCTGLVFISWTTGLIHATSHLVEIVELPFCGPKEIDSFFCDMPLVIKLACLDSHDLDILMNANCGVVAVICFILLLISYTYILTNVLQSSKSGASKALSTCTAHITVVMIFFVPCLFIYVWPLNIIWLDKFLAVFYSVFTPLLNPAIYTLRNKEIKNAMRRFLSNYLFKENP", "length": 311, "header": "tr|A0A9J7H3E3-1|A0A9J7H3E3_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100764529 PE=3 SV=1 CANONICAL=A0A9J7H3E3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764529", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764529", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H3E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E3" }, { "id": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"XP_035304038", "name": "src kinase-associated phosphoprotein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304038" }, "gene_names": [ { "name": "Skap1", "type": "recommended", "evidence": [ { "id": "A0A9J7H3F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3F5" } ] }, { "name": "Skap1", "type": "synonym", "evidence": [ { "id": "XP_035304038", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304038" } ] } ], "protein_names": [ { "name": "Src kinase-associated phosphoprotein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7H3F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3F5/entry#names_and_taxonomy" } ] }, { "name": "Src family-associated phosphoprotein 1", "type": "synonym", "evidence": [ { "id": "A0A9J7H3F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3F5/entry#names_and_taxonomy" } ] }, { "name": "src kinase-associated phosphoprotein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035304038", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304038" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 5% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304038", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304038" } ] }, { "annotation": "Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3F5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3F5#function" }, { "database": "UniProtKB", "id": "ARBA00058951", "url": "https://www.uniprot.org/uniprotkb/ARBA00058951#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3F5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3F5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Skap1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3F5", "locus": {} } ], "crossref": [ { "id": "A0A9J7H3F5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H3F5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12044", "url": 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"Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761440", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761440", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H3F5", "url": "https://www.orthodb.org/?gene=A0A9J7H3F5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15129:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15129:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": 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"MAEVIIVSFYFSKKMLIADAQDFLAEGLRNENLSAGAQDQRDHILRGFQQIKSRYCWDFQPQGGDVGQDSSDDNLNGIHGPPLTSEAFFWSDYQDEGVENILRGAQELDTIIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFLYYANEKSKQPKGTFLIKGYSVRMAPHLRKDSKKESCFELTSQDRRSYEFTALSPAEARDWVDQISFLLKDLSSSTIPCEEEEEEEEEEEKEEETYDDIDGFDSPKSGSQCRAKTLPEPTDEEEDIYEVLPDEDLELEEDAHGTHRRPVDYASYYQGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLIGIVPKDYLTTAFEAEE", "length": 357, "header": "tr|A0A9J7H3F5-1|A0A9J7H3F5_CRIGR Isoform 1 of Src kinase-associated phosphoprotein 1 OS=Cricetulus griseus OX=10029 GN=Skap1 PE=3 SV=1 CANONICAL=A0A9J7H3F5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H3F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3F5/entry#A0A9J7H3F5-1", "sequence": { "sequence": "MAEVIIVSFYFSKKMLIADAQDFLAEGLRNENLSAGAQDQRDHILRGFQQIKSRYCWDFQPQGGDVGQDSSDDNLNGIHGPPLTSEAFFWSDYQDEGVENILRGAQELDTIIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFLYYANEKSKQPKGTFLIKGYSVRMAPHLRKDSKKESCFELTSQDRRSYEFTALSPAEARDWVDQISFLLKDLSSSTIPCEEEEEEEEEEEKEEETYDDIDGFDSPKSGSQCRAKTLPEPTDEEEDIYEVLPDEDLELEEDAHGTHRRPVDYASYYQGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLIGIVPKDYLTTAFEAEE", "length": 357, "header": "tr|A0A9J7H3F5-1|A0A9J7H3F5_CRIGR Isoform 1 of Src kinase-associated phosphoprotein 1 OS=Cricetulus griseus OX=10029 GN=Skap1 PE=3 SV=1 CANONICAL=A0A9J7H3F5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3H1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752285", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752285", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3H1" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3H1", "url": 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eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301689", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301689" } ] }, { "annotation": "Probably involved in membrane protein trafficking.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3I8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3I8#function" }, { "database": "UniProtKB", "id": "ARBA00037350", "url": "https://www.uniprot.org/uniprotkb/ARBA00037350#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3I8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3I8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Scamp4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3I8", "locus": {} } ], "crossref": [ { "id": "100758561", "url": "https://www.ncbi.nlm.nih.gov/gene/100758561", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758561", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758561", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H3I8", "url": "https://www.orthodb.org/?gene=A0A9J7H3I8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10687", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10687", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10687:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10687:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035301689", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301689", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H3I8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3I8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSRVRVSVTHPRILNRKYRSLALQDTRKKGPQIHRRSDQARVRPDGNRSQVSASIRPRPRKYVPVVPRGVGGAARLLGLGEAWRSRGRPSGIESWTLDILDGHCAADPRPLPSVADSRQDSTPEPPHCIKGGPLCLGGRSASTEMAGKENNFPPLPRFVPLKPCFYQDFSDEIPVEHQMLVKRIYQLWMFYCATLGVNLVACLAXWIAGGTQANFGLAMLWLLLFTPCSYVCWFLPSYKAFRADSSFNFMTFFFIFGAQFVVTVIQSISFSGWGVCGWMAAVGFFGVNVGAAVVMLIPAIMFSLSAVMLAITLVKVHRIYLGAGGSFQKAQTEWNTGTWKNPPSREVQFNSFSGNNLPEYPTVPSYPSGGQWP", "length": 374, "header": "tr|A0A9J7H3I8-1|A0A9J7H3I8_CRIGR Isoform 1 of Secretory carrier-associated membrane protein OS=Cricetulus griseus OX=10029 GN=Scamp4 PE=3 SV=1 CANONICAL=A0A9J7H3I8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H3I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3I8/entry#A0A9J7H3I8-1", "sequence": { "sequence": "MSSRVRVSVTHPRILNRKYRSLALQDTRKKGPQIHRRSDQARVRPDGNRSQVSASIRPRPRKYVPVVPRGVGGAARLLGLGEAWRSRGRPSGIESWTLDILDGHCAADPRPLPSVADSRQDSTPEPPHCIKGGPLCLGGRSASTEMAGKENNFPPLPRFVPLKPCFYQDFSDEIPVEHQMLVKRIYQLWMFYCATLGVNLVACLAXWIAGGTQANFGLAMLWLLLFTPCSYVCWFLPSYKAFRADSSFNFMTFFFIFGAQFVVTVIQSISFSGWGVCGWMAAVGFFGVNVGAAVVMLIPAIMFSLSAVMLAITLVKVHRIYLGAGGSFQKAQTEWNTGTWKNPPSREVQFNSFSGNNLPEYPTVPSYPSGGQWP", "length": 374, "header": "tr|A0A9J7H3I8-1|A0A9J7H3I8_CRIGR Isoform 1 of Secretory carrier-associated membrane protein OS=Cricetulus griseus OX=10029 GN=Scamp4 PE=3 SV=1 CANONICAL=A0A9J7H3I8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3I8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3I8" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3I8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3I8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304099", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304099" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3J3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ttll6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3J3", "locus": {} } ], "crossref": [ { "id": "100760107", "url": "https://www.ncbi.nlm.nih.gov/gene/100760107", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760107", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760107", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H3J3", "url": "https://www.orthodb.org/?gene=A0A9J7H3J3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12241", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12241", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12241:SF96", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12241:SF96", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304099", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304099", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H3J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3J3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQCLTSESEEGGKEKEKSIEHLEELQQFVTLAFVIENTQKRLQNGQQHGKKKRKRKRXLVINLSNCRYDSVRRAAQQYGLREAGDNDDWTVYWTDYSVSLERVMEMKSYQKINHFPGMSEICRKDLLARNMSRMLKLFPKDFHFFPRTWCLPADWGDLQTYSRSRKNKTYICKPDSGCQGRGIFITRTVKEIKPGEDMICQLYISKPFIIDGFKFDLRVYVLVTSCDPLRVFVYKEGLARFATTSYSHPCTDNLDEICMHLTNYSINKHSSNFIQDAHSGSKRKLSTFNSYMKAHGYDVEQLWKAIEDVIIKTLISAHPVIKHNYHTCFPSHTLNSACFEILGFDILLDRKLKPWLLEVNHSPSFSTDSKLDKEVKDSLLYDALVLINLGGCDKKKVLEEERKRGRFLQQCPSREMRMEEVKGFQAVRLQKTEEYERKNCGGFRLIYPGLNLEKYEKFFQDNSSLFQNTVASRARELYARQLIQELRQKQQKKFFLKKEKKVDLQGESVSEQARDKILKTGRQKQQQKSKTTTYPPKQCYHPVALVSCTPGLFLNIRGIRNNETAGSLHQQDSKAASLAPCKLMPARHYSSVPDLRNSNSSCCGPELQKCNSKIKEVKSAFSVNIISNNTLPLTSEETSPEPTARLSSSLESLASLNLTNSPECSSSESVHTVSYRCKQQGVPYKLILEKNLTPPVSYKPKILDPNWTLLKNEVKRQHLMSEILQKVQIKKKRSLFLTSKLRNPSFTKEWCSHSRNSSRKKEMGVSSVLLLRGSRRNAASLNDLLVIATQARLDPRPSRGHSGTTRDLGTTIDPGTTSDRAHRTRSTLPLSDLLSERM", "length": 839, "header": "tr|A0A9J7H3J3-1|A0A9J7H3J3_CRIGR Isoform 1 of LOW QUALITY PROTEIN: tubulin polyglutamylase TTLL6 isoform X3 OS=Cricetulus griseus OX=10029 GN=Ttll6 PE=3 SV=1 CANONICAL=A0A9J7H3J3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H3J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3J3/entry#A0A9J7H3J3-1", "sequence": { "sequence": "MLQCLTSESEEGGKEKEKSIEHLEELQQFVTLAFVIENTQKRLQNGQQHGKKKRKRKRXLVINLSNCRYDSVRRAAQQYGLREAGDNDDWTVYWTDYSVSLERVMEMKSYQKINHFPGMSEICRKDLLARNMSRMLKLFPKDFHFFPRTWCLPADWGDLQTYSRSRKNKTYICKPDSGCQGRGIFITRTVKEIKPGEDMICQLYISKPFIIDGFKFDLRVYVLVTSCDPLRVFVYKEGLARFATTSYSHPCTDNLDEICMHLTNYSINKHSSNFIQDAHSGSKRKLSTFNSYMKAHGYDVEQLWKAIEDVIIKTLISAHPVIKHNYHTCFPSHTLNSACFEILGFDILLDRKLKPWLLEVNHSPSFSTDSKLDKEVKDSLLYDALVLINLGGCDKKKVLEEERKRGRFLQQCPSREMRMEEVKGFQAVRLQKTEEYERKNCGGFRLIYPGLNLEKYEKFFQDNSSLFQNTVASRARELYARQLIQELRQKQQKKFFLKKEKKVDLQGESVSEQARDKILKTGRQKQQQKSKTTTYPPKQCYHPVALVSCTPGLFLNIRGIRNNETAGSLHQQDSKAASLAPCKLMPARHYSSVPDLRNSNSSCCGPELQKCNSKIKEVKSAFSVNIISNNTLPLTSEETSPEPTARLSSSLESLASLNLTNSPECSSSESVHTVSYRCKQQGVPYKLILEKNLTPPVSYKPKILDPNWTLLKNEVKRQHLMSEILQKVQIKKKRSLFLTSKLRNPSFTKEWCSHSRNSSRKKEMGVSSVLLLRGSRRNAASLNDLLVIATQARLDPRPSRGHSGTTRDLGTTIDPGTTSDRAHRTRSTLPLSDLLSERM", "length": 839, "header": "tr|A0A9J7H3J3-1|A0A9J7H3J3_CRIGR Isoform 1 of LOW QUALITY PROTEIN: tubulin polyglutamylase TTLL6 isoform X3 OS=Cricetulus griseus OX=10029 GN=Ttll6 PE=3 SV=1 CANONICAL=A0A9J7H3J3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3J3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3J3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760107", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760107", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "tubulin-glutamic acid ligase activity", "id": "GO:0070740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070740", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3J3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": 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"https://www.ncbi.nlm.nih.gov/protein/XP_035301705" } ] } ], "protein_names": [ { "name": "T-cell surface glycoprotein CD3 zeta chain", "type": "recommended", "evidence": [ { "id": "A0A9J7H3K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3K0/entry#names_and_taxonomy" } ] }, { "name": "T-cell receptor T3 zeta chain", "type": "synonym", "evidence": [ { "id": "A0A9J7H3K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3K0/entry#names_and_taxonomy" } ] }, { "name": "T-cell surface glycoprotein CD3 zeta chain", "type": "synonym", "evidence": [ { "id": "XP_035301705", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301705" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 44% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301705", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301705" } ] }, { "annotation": "Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD247/CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. CD247/CD3Z ITAMs phosphorylation creates multiple docking sites for the protein kinase ZAP70 leading to ZAP70 phosphorylation and its conversion into a catalytically active enzyme. Plays an important role in intrathymic T-cell differentiation. 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computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301769", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301769" } ] }, { "annotation": "F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization. Forms, with CAPZB, the barbed end of the fast growing ends of actin filaments in the dynactin complex and stabilizes dynactin structure. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035293123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293123" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3Q3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Phactr3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3Q3", "locus": {} } ], "crossref": [ { "id": "A0A9J7H3Q3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H3Q3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100765892", "url": "https://www.ncbi.nlm.nih.gov/gene/100765892", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765892", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765892", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H3Q3", "url": "https://www.orthodb.org/?gene=A0A9J7H3Q3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12751", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12751", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12751:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12751:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02755", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02755", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035293123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293123", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H3Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASEDGSSCLVSRGRSQSDPSFLSDSSATSTDAGENPDEMDQTPPARSEPLISGIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAGRHGREELIKQGLLEMMEQDAESKACSPNEGSQPVQSEPSTAEQETLTSDGIQPGSPLASGTDEASQAELLSSDAHLDDTAKTPTASSAEGADDGSILPTSDELSQALAGSDSPDSPPRPLERSASQLPSPPLLPTPPPKASCKATKTVTGQAALFQGPSMKSNEPALRGQLATPTGSPHLTTVHRPLPPSRVIEELHRALATKHRQDSFQGRECRGSPKKRMDVRLSRTSSMERGKEREEMWSFDGASENKRTAAKDSEENKENLMLSSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVARAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTR", "length": 554, "header": "tr|A0A9J7H3Q3-1|A0A9J7H3Q3_CRIGR Isoform 1 of Phosphatase and actin regulator OS=Cricetulus griseus OX=10029 GN=Phactr3 PE=3 SV=1 CANONICAL=A0A9J7H3Q3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H3Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3Q3/entry#A0A9J7H3Q3-1", "sequence": { "sequence": "MAASEDGSSCLVSRGRSQSDPSFLSDSSATSTDAGENPDEMDQTPPARSEPLISGIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAGRHGREELIKQGLLEMMEQDAESKACSPNEGSQPVQSEPSTAEQETLTSDGIQPGSPLASGTDEASQAELLSSDAHLDDTAKTPTASSAEGADDGSILPTSDELSQALAGSDSPDSPPRPLERSASQLPSPPLLPTPPPKASCKATKTVTGQAALFQGPSMKSNEPALRGQLATPTGSPHLTTVHRPLPPSRVIEELHRALATKHRQDSFQGRECRGSPKKRMDVRLSRTSSMERGKEREEMWSFDGASENKRTAAKDSEENKENLMLSSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVARAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTR", "length": 554, "header": "tr|A0A9J7H3Q3-1|A0A9J7H3Q3_CRIGR Isoform 1 of Phosphatase and actin regulator OS=Cricetulus griseus OX=10029 GN=Phactr3 PE=3 SV=1 CANONICAL=A0A9J7H3Q3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 235, "start_aa": "Thr", "end_pos": 235, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr235", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3Q3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3Q3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765892", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765892", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3Q3" } ], "pmid": "" }, { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004864", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3Q3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3Q3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 235 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 385, "end_pos": 387 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H3R0-1", "uniprot_ac": "A0A9J7H3R0", "uniprot_id": "A0A9J7H3R0_CRIGR", "mass": { "chemical_mass": 114426.0, "monoisotopic_mass": 114426.0 }, "refseq": { "ac": "XP_035301812", "name": "LOW QUALITY PROTEIN: rap guanine nucleotide exchange factor 5 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301812" }, "gene_names": [ { "name": "Rapgef5", "type": "recommended", "evidence": [ { "id": "A0A9J7H3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3R0" } ] }, { "name": "Rapgef5", "type": "synonym", "evidence": [ { "id": "XP_035301812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301812" } ] } ], "protein_names": [ { "name": "Rap guanine nucleotide exchange factor 5", "type": "recommended", "evidence": [ { "id": "A0A9J7H3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3R0/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: rap guanine nucleotide exchange factor 5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035301812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301812" } ] }, { "name": "M-Ras-regulated Rap GEF", "type": "synonym", "evidence": [ { "id": "A0A9J7H3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3R0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 13% of CDS bases frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301812", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301812" } ] }, { "annotation": "Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3R0#function" }, { "database": "UniProtKB", "id": "ARBA00055877", "url": "https://www.uniprot.org/uniprotkb/ARBA00055877#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3R0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rapgef5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3R0", "locus": {} } ], "crossref": [ { "id": "cd00155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04437", "url": 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"Protein Classification" ] }, { "id": "IPR019804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769866", "url": 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"MSPIGIVSKDKQVGREQWDTDVLANSKNISLCVEELNLGLCTGQVNMGAPQFRPPGIAVIHTALSVHSLPSTSVRRRRLTGAGGTVRSGASSAGGGSVRAPEVSGGAGGAGSTWAGRGGARGEPIVRKSPLLLRARSAVGRRVKMQPPCEXPALASAAPGDGPLPQPERPGAEREPPAASLRPRLKDLPALLRSGLTLRRKRSAAGARTLSRRISNPYLEHSPSQIYGENSSCAGRALRNIIIVQGADLVKDRVNLKGFYRRSCVGSELVDWLLEHCPFVQCRSMAIGVWQLLLDMGIMSSVDQHLYFQDNYVFYQFSSEECSYLYCEFEREEEWQNGVKLLLQLVHLIPARAGICDLSHQKVEDSEESSDEILARLTSAVQRELAAVIALKARKSAIEQDDENTDKHIEVIEASDVPDPQAGVMCKLQERDDIGRIELVQKLARDNCPFLQIDKKEPEKSEQQDDEVTMVQVKEQGLSVLVLKKVAASCGPAPTSAAESQARYVVVSGTPEKILEHLLNDLHLAEVQHKETDTLLDDFLLTYTVFMTTDDLCQALLRHYSAKKYQGEEENSDVPCRKRKVLHLVSQWIALYKDWLHEDEHSKMFLKTIYRNVLDDVYEYPILEKELKEFQKILGMHRRHTVDEYSPQRKNKALFHQFSLKENWLQHRGTVAETEEIFCHVYITEHSYVSVKAKVSSTAQEILKVVAEKLQRAEEDLALVAIMFSGEKHEFQPNDLVISKSLEASGRIFVYRKDLADTLNPFADNEESQQRPVRILGMNTWDLALELMSFDWSLFNSIHEQELIYFTFSRQGSGEHTVNLSLLLQRCNEVQLWVATEILLCSQLGKRVQLVKKFIKIAAHCKAQQNLNSFFAIVMGLNTASVSRLSQTWEKIPGKFKKLFSELESLTDPSLNHKAYRDAFKKMKPPKIPFMPLLLKDVTFIHEGNKTFLDNLVNFEKLHMIADTVRTLRHCRTNQFGSDMSPKEQQELKSYVNHLYVIDSQQALFELSHRLEPRA", 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"length": 1015, "header": "tr|A0A9J7H3R0-1|A0A9J7H3R0_CRIGR Isoform 1 of Rap guanine nucleotide exchange factor 5 OS=Cricetulus griseus OX=10029 GN=Rapgef5 PE=4 SV=1 CANONICAL=A0A9J7H3R0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 495, "start_aa": "Thr", "end_pos": 495, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr495", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3R0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3R0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769866", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769866", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3R0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3R0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3R0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3R0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 819, "end_pos": 821, "annotation": "n_glycosylation_sequon" }, { 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S8/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein kinase WNK4 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_035304110", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304110" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 167 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) and transcript sequence (IACG01035228.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304110", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304110" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3S8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Wnk4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S8", "locus": {} } ], "crossref": [ { "id": "A0A9J7H3S8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H3S8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14033", "database": "CDD", "categories": [ "Protein Classification" ] }, 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"MLEPRTTETGAPMSQTEADLALRPPPSLTSSGPTRLGPPPRRVRRFSGKAEPRPRSSRPSRRSSVDLGLLSSWSQPASLLPEPPDPPDSAGPTRSPPSCSKETPEGTWTGAAPVKAADSASPELMGPSVGPGSREPPKLLDAAARERRREQEEKEDTETQAVATSPDGRYLKFDIEIGRGSFKTVYRGLDTDTTVEVAWCELQTRKLSRAERQRFSEEVEMLKGLQHPNIVRFYDSWKSVLRGQVCIVLVTELMTSGTLKTYLRRFREMKPRVLQRWSRQILRGLHFLHSRVPPILHRDLKCDNVFITGPSGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDEAVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGTKPNSFYKVKMPEVKEIIEGCIRTDKNERFTIQDLLAHAFFREERGVHVELAEEDDGEKPGLKLWLRMEDTRRGGRPRDNQAIEFLFQLGRDAAEEVAQEMVALGLVCEADYQPVARAVRERVAAIQRKREKLRKARELKVLPPESGPPPATVSMAPGPPSAFPPEPEEPEADQHQSFLFRHASYSSTTSDCETDGYLSSSGFLDASDPALQPPGGVPSSPAESHLCLPSGFALSIPRSGPGSDFSPGDSYASDAASGLSDMGEGGQMRTTPAKNLRRRPRSRLRVTSVSDQNDRVVECQLQTHNSKMVTFRFDLDGDSPEEIAAAMVYNEFILPSERDGFLSRIREIIQRVETLLKRDPGPPEAAEDALSPQEEPATPPALPGPSNAEPQRSTAPEQRSWAAFSTSPSSPGTPLSPGTPFSPGTPPVFPCPVFPITSPSCHPCPFSQPPSPPLPSFSSESQFPLPPSHLPVSSLPTSSPSSSQVTLNPACFPVCPSPPPLPSTAAAPLLSLASAFSLAVMTVAQSLLSPSPGLLSQSPPGPLSSTPLPLASCGQESLSPQKAETECEVSQNSVQPLLGEARLAPISEEGKPQLVGRFQVTSSKEPAEPPLQSAPPTLSSSLKLPTPPLTSESSDTENSAAGGPEPREALAESDRAAEGLGVAIEEEGHDGVRIGGSSPLLSHPSPVWMNYSYSSLCLSSEESESSGEDEEFWAELQNLRQKHLSEVEALQTLQKKEIEDLYSRLGKQPPPGIVAPAAMLSCRQRRLSKGSFPTSRRNSLQRSDLPGPGIMRRNSLSGSSTGSQEQRASKGVTFAGDVGRM", "length": 1209, "header": "tr|A0A9J7H3S8-1|A0A9J7H3S8_CRIGR Isoform 1 of Serine/threonine-protein kinase WNK4 OS=Cricetulus griseus OX=10029 GN=Wnk4 PE=4 SV=1 CANONICAL=A0A9J7H3S8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 93, "start_aa": "Thr", "end_pos": 93, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr93", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3S8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3S8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761172", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761172", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3S8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3S8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3S8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of metal ion transport", "id": "GO:0010959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010959", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3S8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1078, "end_pos": 1080, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = 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"A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3E2-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7F9C4-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2M7I3-1", "A0A8C2N3I1-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A9J7JQZ1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A3L7I1E7-1", "A0A9J7GBL6-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7H540-1", "A0A9J7H949-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H8W5-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", 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"database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3HX91-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", "A0A8C2QND0-1", "G3HXQ8-1", 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"A0A8C2LC89-1", "A0A8C2LCN7-1", "A0A8C2LEI8-1", "A0A8C2LH99-1", "A0A9J7GAB0-1", "A0A8C2LK72-1", "A0A8C2LMC9-1", "A0A8C2LMJ0-1", "A0A9J7JQV6-1", "A0A8C2LPR4-1", "A0A8C2LQB2-1", "A0A8C2LVV5-1", "A0A8C2MYH0-1", "A0A8C2MV78-1", "A0A9J7JHJ2-1", "A0A8C2N0J6-1", "A0A8C2N210-1", "A0A8C2N457-1", "A0A8C2N4W2-1", "A0A8C2N756-1", "A0A8C2QGY5-1", "A0A8C2QJ34-1", "A0A8C2QJA4-1", "A0A9J7KDV7-1", "A0A8C2QNX2-1", "A0A8C2QPB0-1", "A0A9J7EVN3-1", "A0A9J7F0N6-1", "A0A8C2M6E6-1", "A0A9J7F2L0-1", "A0A9J7F3R3-1", "A0A9J7F5B0-1", "A0A8C2LDE5-1", "A0A9J7JB60-1", "A0A9J7F927-1", "A0A9J7F8V5-1", "A0A9J7F8T0-1", "A0A9J7FBT0-1", "A0A9J7FD79-1", "A0A9J7FLY5-1", "A0A9J7K2Q7-1", "A0A3L7I1R2-1", "A0A9J7FYY3-1", "A0A9J7GBI2-1", "A0A9J7FN68-1", "A0A9J7FNF0-1", "A0A9J7FS53-1", "A0A9J7FUL0-1", "A0A9J7FVR6-1", "A0A9J7FZH7-1", "A0A9J7FZW1-1", "A0A9J7G1H0-1", "A0A9J7G5F3-1", "A0A9J7G5N9-1", "A0A8C2LFT9-1", "A0A9J7G9D1-1", "A0A8C2MB66-1", "A0A9J7GD76-1", "A0A8C2LQS5-1", "A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GT89-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JIF8-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7F9C4-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A8C2M7I3-1", "A0A8C2MBI9-1", "A0A9J7JQZ1-1", "A0A8C2N3I1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7GBL6-1", "A0A9J7H8W5-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7H540-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H949-1", "A0A9J7GQY0-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] } ] }, { "uniprot_ac": "A0A8C2M3Y9", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] } ] }, { "uniprot_ac": "A0A8C2M497", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] 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"A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] } ] }, { "uniprot_ac": "A0A8C2QLT0", "gene_name": "Nek9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] } ] }, { "uniprot_ac": "A0A8C2QMB3", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] } ] }, { "uniprot_ac": "A0A8C2QND0", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] } ] }, { "uniprot_ac": "A0A8C2QNX2", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] } ] }, { "uniprot_ac": "A0A8C2QPB0", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] } ] }, { "uniprot_ac": "A0A9J7EUQ5", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] } ] }, { "uniprot_ac": "A0A9J7EVK4", "gene_name": "Bmp2k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] } ] }, { "uniprot_ac": "A0A9J7EVN3", "gene_name": "LOC100754361", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] } ] }, { "uniprot_ac": "A0A9J7EXX8", "gene_name": "LOC113832238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] } ] }, { "uniprot_ac": "A0A9J7F0J6", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": 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"A0A9J7F821", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] } ] }, { "uniprot_ac": "A0A9J7GIN7", "gene_name": "Eif2ak3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] } ] }, { "uniprot_ac": "A0A9J7GJE4", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] } ] }, { "uniprot_ac": "A0A9J7GK55", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] } ] }, { "uniprot_ac": "A0A9J7GLT3", "gene_name": "LOC113838166", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] } ] }, { "uniprot_ac": "A0A9J7GMF3", "gene_name": "LOC103158537", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] } ] }, { "uniprot_ac": "A0A9J7GMK5", "gene_name": "Sbk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] } ] }, { "uniprot_ac": "A0A9J7GP29", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] } ] }, { "uniprot_ac": "A0A9J7GQ42", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] } ] }, { "uniprot_ac": "A0A9J7GQY0", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] } ] }, { "uniprot_ac": "A0A9J7GR05", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] } ] }, { "uniprot_ac": "A0A9J7GR29", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] } ] }, { "uniprot_ac": "A0A9J7GRB5", "gene_name": "LOC113838167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRB5" } ] } ] }, { "uniprot_ac": "A0A9J7GRC1", "gene_name": "LOC100764806", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRC1" } ] } ] }, { "uniprot_ac": "A0A9J7GT89", "gene_name": "LOC100774420", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] } ] }, { "uniprot_ac": "A0A9J7GTU0", "gene_name": "LOC100757707", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTU0" } ] } ] }, { "uniprot_ac": "A0A9J7GVC9", "gene_name": "LOC100759146", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVC9" } ] } ] }, { "uniprot_ac": "A0A9J7GX76", "gene_name": "Dapk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GX76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GX76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX76" } ] } ] }, { "uniprot_ac": "A0A9J7GY39", "gene_name": "Akt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] } ] }, { "uniprot_ac": "A0A9J7GZH5", "gene_name": "Ripk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GZH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GZH5", "database": "UniProtKB", "url": 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{ "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302854" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3T1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100760210", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T1", "locus": {} } ], "crossref": [ { "id": "A0A9J7H3T1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H3T1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100760210", "url": "https://www.ncbi.nlm.nih.gov/gene/100760210", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760210", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760210", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H3T1", "url": "https://www.orthodb.org/?gene=A0A9J7H3T1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302854", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H3T1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEHSNDTKVTEFILLGFANQQEFWHILFVVFLVIYLATLVGNIGMILLIQLHSSLHTPMYFFLQHLAFVDLCYSSAITPKTLQNFVSTKPSVSFTGCIVQLLVYGTFVTSDCFILAAMAVDRYVAICNPLRYPVIMSQRLCILLLLGSYTMGFLNASVNTIFTFLSNFCKSNAINHFFCDVPPILALSCSSIDLNIMVLTIFVGFNLTFTVSVVIFSYTFILAAILRMSSASGRRKAFSTCASHMTAVTIFYGTLSYMYVLHGTNKSQEQEKVASVFYGIMIPMLNPLIYSLRNQDVIEVLRNIRNKCV", "length": 309, "header": "tr|A0A9J7H3T1-1|A0A9J7H3T1_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100760210 PE=3 SV=1 CANONICAL=A0A9J7H3T1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H3T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3T1/entry#A0A9J7H3T1-1", "sequence": { "sequence": "MEHSNDTKVTEFILLGFANQQEFWHILFVVFLVIYLATLVGNIGMILLIQLHSSLHTPMYFFLQHLAFVDLCYSSAITPKTLQNFVSTKPSVSFTGCIVQLLVYGTFVTSDCFILAAMAVDRYVAICNPLRYPVIMSQRLCILLLLGSYTMGFLNASVNTIFTFLSNFCKSNAINHFFCDVPPILALSCSSIDLNIMVLTIFVGFNLTFTVSVVIFSYTFILAAILRMSSASGRRKAFSTCASHMTAVTIFYGTLSYMYVLHGTNKSQEQEKVASVFYGIMIPMLNPLIYSLRNQDVIEVLRNIRNKCV", "length": 309, "header": "tr|A0A9J7H3T1-1|A0A9J7H3T1_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100760210 PE=3 SV=1 CANONICAL=A0A9J7H3T1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305052", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305052" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3U9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3U9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113837388", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3U9", "locus": {} } ], "crossref": [ { "id": "cd16843", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16843", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113837388", "url": "https://www.ncbi.nlm.nih.gov/gene/113837388", "database": "GeneID", "categories": [ 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303692", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303692" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H3V0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3V0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100762011", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3V0", "locus": {} } ], "crossref": [ { "id": "A0A9J7H3V0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H3V0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305129", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305129" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H401", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H401" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Akt2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H401", "locus": {} } ], "crossref": [ { "id": "A0A9J7H401", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H401", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01241", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01241", "database": "CDD", "categories": [ "Protein Classification" ] }, 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"categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039026", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039026", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768351", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768351", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H401", "url": "https://www.orthodb.org/?gene=A0A9J7H401", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24351", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24351", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00433", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00433", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305129", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305129", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H401", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H401", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H401-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H401-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEDPDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRTIQMVANSLKHRDPGDNALEYKCGSPSDSSSSEMMEVAVNKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQRKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGSLELDQRTHFPQFSYSASIRE", "length": 481, "header": "tr|A0A9J7H401-1|A0A9J7H401_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Akt2 PE=3 SV=1 CANONICAL=A0A9J7H401-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H401-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H401/entry#A0A9J7H401-1", "sequence": { "sequence": "MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEDPDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRTIQMVANSLKHRDPGDNALEYKCGSPSDSSSSEMMEVAVNKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQRKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGSLELDQRTHFPQFSYSASIRE", "length": 481, "header": "tr|A0A9J7H401-1|A0A9J7H401_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Akt2 PE=3 SV=1 CANONICAL=A0A9J7H401-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H401", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H401" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H401", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H401" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768351", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768351", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H401", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H401" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H401", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H401" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", "A0A8C2QND0-1", "G3HXQ8-1", "G3I724-1", "A0A8C2M0A2-1", "A0A9J7K2S5-1", "A0A8C2MMZ5-1", "A0A8C2QH69-1", "A0A8C2QL63-1", "A0A9J7K953-1", "A0A9J7G3C1-1", "A0A9J7GFS3-1", "A0A9J7JBH0-1", "A0A9J7FGD3-1", "A0A9J7FKM1-1", "A0A9J7JKJ1-1", "A0A9J7G180-1", "A0A9J7JTL3-1", "A0A9J7GQ42-1", "A0A9J7EZ53-1", "A0A9J7J5Z8-1", "A0A9J7EVK4-1", "A0A9J7F0G6-1", "A0A9J7FCC7-1", "A0A9J7K3S4-1", "A0A9J7GAF4-1", "A0A9J7GBF4-1", "A0A8C2MTI7-1", "A0A9J7J1N3-1", "A0A9J7F4P4-1", "A0A9J7JNU2-1", "A0A9J7FZY8-1", "A0A9J7H3M5-1", "A0A9J7JJV6-1", "A0A9J7GJE4-1", "A0A8C2LY52-1", "A0A9J7H8U3-1", "A0A9J7F821-1", "A0A8C2N185-1", "A0A9J7KFV8-1", "A0A8C2MQM0-1", "A0A8C2N310-1", "A0A9J7J6H1-1", "A0A9J7H2P9-1", "A0A9J7H4N5-1", "A0A3L7GPC7-1", "A0A9J7H6V8-1", "A0A3L7HV37-1", "A0A8C2LTZ7-1", "A0A9J7K7D8-1", "A0A8C2LDU9-1", "A0A8C2LTW4-1", "A0A9J7JAM4-1", "A0A9J7JXM2-1", "A0A9J7JRJ8-1", "A0A8C2QEB8-1", "A0A3L7HKC4-1", "A0A8C2LI14-1", "A0A8C2QDX9-1", "A0A9J7G1D9-1", "A0A9J7F985-1", "A0A8C2MCX3-1", "A0A8C2MEU5-1", "A0A8C2MFN1-1", "A0A8C2MMI4-1", "A0A9J7JAB2-1", "A0A9J7G969-1", "A0A8C2MQ42-1", "A0A8C2MR08-1", "A0A8C2MUQ5-1", "A0A9J7FZA7-1", "A0A8C2N3C9-1", "A0A8C2N6L4-1", "A0A8C2N9X1-1", "A0A8C2QHF9-1", "A0A8C2QI80-1", "A0A8C2QKP7-1", "A0A9J7F842-1", "A0A9J7FFS7-1", "A0A9J7FI14-1", "A0A9J7FJ23-1", "A0A9J7JLH7-1", "A0A9J7G270-1", "A0A8C2MH43-1", "A0A9J7FZ18-1", "A0A9J7G368-1", "A0A9J7G6S5-1", "A0A9J7K1H4-1", "A0A9J7H2T6-1", "A0A9J7H3N1-1", "A0A9J7H8L4-1", "A0A9J7JIW6-1", "A0A9J7JRI3-1", "A0A061I9F9-1", "A0A061HUS7-1", "A0A061HVM6-1", "A0A061I033-1", "A0A061I8L6-1", "A0A8C2MQS3-1", "A0A9J7F0Y2-1", "A0A061ILI7-1", "A0A9J7EZ49-1", "A0A8C2M9B6-1", "A0A8C2ML15-1", "A0A8C2LY02-1", "A0A8C2LZT2-1", "A0A8C2M165-1", "A0A8C2M5G2-1", "A0A8C2M3Y9-1", "A0A8C2M5A7-1", "A0A8C2M6A3-1", "A0A8C2MBW2-1", "A0A9J7JYU7-1", "A0A8C2MJ02-1", "A0A9J7JQD1-1", "A0A8C2MMQ4-1", "A0A8C2MQ73-1", 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"A0A9J7FZH7-1", "A0A9J7FZW1-1", "A0A9J7G1H0-1", "A0A9J7G5N9-1", "A0A8C2LFT9-1", "A0A9J7GBI2-1", "A0A8C2MB66-1", "A0A8C2LQS5-1", "A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3E2-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7F9C4-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2M7I3-1", "A0A8C2N3I1-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A9J7JQZ1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A3L7I1E7-1", "A0A9J7GBL6-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7H540-1", "A0A9J7H949-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H8W5-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GQY0-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7JPF2-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K3L1-1", "A0A9J7K6R5-1", "A0A9J7KB54-1", "A0A9J7K851-1", "A0A9J7KCM5-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7JA07-1", "A0A3L7HMX8-1", "A0A061HZ27-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2MP62-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "A0A9J7JYC5-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", 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"A0A3L7I1R2-1", "A0A9J7FYY3-1", "A0A9J7GBI2-1", "A0A9J7FN68-1", "A0A9J7FNF0-1", "A0A9J7FS53-1", "A0A9J7FUL0-1", "A0A9J7FVR6-1", "A0A9J7FZH7-1", "A0A9J7FZW1-1", "A0A9J7G1H0-1", "A0A9J7G5F3-1", "A0A9J7G5N9-1", "A0A8C2LFT9-1", "A0A9J7G9D1-1", "A0A8C2MB66-1", "A0A9J7GD76-1", "A0A8C2LQS5-1", "A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GT89-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JIF8-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7F9C4-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A8C2M7I3-1", "A0A8C2MBI9-1", "A0A9J7JQZ1-1", "A0A8C2N3I1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7GBL6-1", "A0A9J7H8W5-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7H540-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H949-1", "A0A9J7GQY0-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] } ] }, { "uniprot_ac": "A0A8C2M3Y9", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] } ] }, { "uniprot_ac": "A0A8C2M497", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] } ] }, { "uniprot_ac": "A0A8C2N185", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] } ] }, { "uniprot_ac": "A0A8C2N210", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] } ] }, { "uniprot_ac": "A0A8C2N3I1", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] } ] }, { "uniprot_ac": "A0A8C2N3U2", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] } ] }, { "uniprot_ac": "A0A8C2N457", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] } ] }, { "uniprot_ac": "A0A8C2N4W2", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] } ] }, { "uniprot_ac": "A0A8C2N6L4", "gene_name": "Prkg1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N6L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L4" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8C2N6L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L4" } ] } ] }, { "uniprot_ac": "A0A8C2N756", "gene_name": "Map2k5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N756" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2N756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N756" } ] } ] }, { "uniprot_ac": "A0A8C2N9X1", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N9X1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2N9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N9X1" } ] } ] }, { "uniprot_ac": "A0A8C2QDX9", "gene_name": "Csnk1g1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] } ] }, { "uniprot_ac": "A0A8C2QEB8", "gene_name": "Bub1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEB8" } ] } ] }, { "uniprot_ac": "A0A8C2QGY5", "gene_name": "Ttbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QGY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGY5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QGY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGY5" } ] } ] }, { "uniprot_ac": "A0A8C2QH69", "gene_name": "Sgk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QH69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QH69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH69" } ] } ] }, { "uniprot_ac": "A0A8C2QHF9", "gene_name": "Lrrk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] } ] }, { "uniprot_ac": "A0A8C2QHS8", "gene_name": "Ripk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] } ] }, { "uniprot_ac": "A0A8C2QI80", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] } ] }, { "uniprot_ac": "A0A8C2QIA1", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] } ] }, { "uniprot_ac": "A0A8C2QJ34", "gene_name": "Oxsr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8C2QL63", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] } ] }, { "uniprot_ac": "A0A8C2QLT0", "gene_name": "Nek9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] } ] }, { "uniprot_ac": "A0A8C2QMB3", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] } ] }, { "uniprot_ac": "A0A8C2QND0", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] } ] }, { "uniprot_ac": "A0A8C2QNX2", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] } ] }, { "uniprot_ac": "A0A8C2QPB0", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] } ] }, { "uniprot_ac": "A0A9J7EUQ5", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] } ] }, { "uniprot_ac": "A0A9J7EVK4", "gene_name": "Bmp2k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] } ] }, { "uniprot_ac": "A0A9J7EVN3", "gene_name": "LOC100754361", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] } ] }, { "uniprot_ac": "A0A9J7EXX8", "gene_name": "LOC113832238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] } ] }, { "uniprot_ac": "A0A9J7F0J6", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] } ] }, { "uniprot_ac": "A0A9J7F1D2", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F821", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] } ] }, { "uniprot_ac": "A0A9J7F8T0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] } ] }, { "uniprot_ac": "A0A9J7GIN7", "gene_name": "Eif2ak3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] } ] }, { "uniprot_ac": "A0A9J7GJE4", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] } ] }, { "uniprot_ac": "A0A9J7GK55", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] } ] }, { "uniprot_ac": "A0A9J7GLT3", "gene_name": "LOC113838166", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] } ] }, { "uniprot_ac": "A0A9J7GMF3", "gene_name": "LOC103158537", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] } ] }, { "uniprot_ac": "A0A9J7GMK5", "gene_name": "Sbk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] } ] }, { "uniprot_ac": "A0A9J7GP29", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] } ] }, { "uniprot_ac": "A0A9J7GQ42", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] } ] }, { "uniprot_ac": "A0A9J7GQY0", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] } ] }, { "uniprot_ac": "A0A9J7GR05", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] } ] }, { "uniprot_ac": "A0A9J7GR29", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] } ] }, { "uniprot_ac": "A0A9J7GRB5", "gene_name": "LOC113838167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A9J7GTU0", "gene_name": "LOC100757707", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTU0" } ] } ] }, { "uniprot_ac": "A0A9J7GVC9", "gene_name": "LOC100759146", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVC9" } ] } ] }, { "uniprot_ac": "A0A9J7GX76", "gene_name": "Dapk1", 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} ] }, { "uniprot_ac": "A0A9J7JA07", "gene_name": "LOC100750629", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA07" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA07" } ] } ] }, { "uniprot_ac": "A0A9J7JAB2", "gene_name": "Stk24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAB2" } ] } ] }, { "uniprot_ac": "A0A9J7JAM4", "gene_name": "Sik1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JAM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAM4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JAM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAM4" } ] } ] }, { "uniprot_ac": "A0A9J7JB60", "gene_name": "Dclk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JB60" } ] } ] }, { "uniprot_ac": "A0A9J7JBH0", "gene_name": "Srpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JBH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JBH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH0" } ] } ] }, { "uniprot_ac": "A0A9J7JDU1", "gene_name": "Cdc42bpg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JDU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDU1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JDU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDU1" } ] } ] }, { "uniprot_ac": "A0A9J7JGG9", "gene_name": "Riok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A9J7JGR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR2" } ] } ] }, { "uniprot_ac": "A0A9J7JHJ2", "gene_name": "Mast2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = 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This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304610", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304610" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H422", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H422" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100770111", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H422", "locus": {} } ], "crossref": [ { "id": "A0A9J7H422", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H422", "database": "AlphaFoldDB", "categories": [] }, { "id": "100770111", "url": "https://www.ncbi.nlm.nih.gov/gene/100770111", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003653", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003653", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770111", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770111", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H422", "url": "https://www.orthodb.org/?gene=A0A9J7H422", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12606", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12606", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12606:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12606:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02902", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02902", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304610", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304610", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H422", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H422", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H422-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H422-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWKPKQCGMEMKPEASGQGRKRKKQDEVWREMVPEALGQGVKPKYQDEGGTDLEFEQPRKARKRVSQEQRDLELLSEQLSKDQIQKRGEENPGQLKPPERGKGPQEQAATGRKSAVGGKGRKRPYCVMEEYDQPHQREKYQKLLQDLQQSDHVNSDPHRAQTTLMDTLKIKGCVEGHSRGSRTTQRDPKRSTVVAATECLSPDKREKLCSEKSSDTQKKDGVNLEGRREHHGEPDLLGAQAQIFLHKMPVFTAKKKPAAEQQKGRGMEEVLDVTEDMEKEIKNALGPGPQEEILSRAFKLQITRGDIQTLENGQWLNDEIINFYMNLLVERNENQGYPALHVFSTFFYPKLKHGGYSSVKRWTRGMDLFEKEIVLVPIHRKVHWSLIVIDLRKQSIVYLDSMGQTGQNICETIFQYLQNESKTRRSIELDPLEWKQYSVTSEEIPRQLNGSDCGMFTCKYADYISRDQPVTFSQQHMPIFRKRMVWEILHSHLL", "length": 494, "header": "tr|A0A9J7H422-1|A0A9J7H422_CRIGR Isoform 1 of Sentrin-specific protease 2-like OS=Cricetulus griseus OX=10029 GN=LOC100770111 PE=3 SV=1 CANONICAL=A0A9J7H422-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H422-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H422/entry#A0A9J7H422-1", "sequence": { "sequence": "MWKPKQCGMEMKPEASGQGRKRKKQDEVWREMVPEALGQGVKPKYQDEGGTDLEFEQPRKARKRVSQEQRDLELLSEQLSKDQIQKRGEENPGQLKPPERGKGPQEQAATGRKSAVGGKGRKRPYCVMEEYDQPHQREKYQKLLQDLQQSDHVNSDPHRAQTTLMDTLKIKGCVEGHSRGSRTTQRDPKRSTVVAATECLSPDKREKLCSEKSSDTQKKDGVNLEGRREHHGEPDLLGAQAQIFLHKMPVFTAKKKPAAEQQKGRGMEEVLDVTEDMEKEIKNALGPGPQEEILSRAFKLQITRGDIQTLENGQWLNDEIINFYMNLLVERNENQGYPALHVFSTFFYPKLKHGGYSSVKRWTRGMDLFEKEIVLVPIHRKVHWSLIVIDLRKQSIVYLDSMGQTGQNICETIFQYLQNESKTRRSIELDPLEWKQYSVTSEEIPRQLNGSDCGMFTCKYADYISRDQPVTFSQQHMPIFRKRMVWEILHSHLL", "length": 494, "header": "tr|A0A9J7H422-1|A0A9J7H422_CRIGR Isoform 1 of Sentrin-specific protease 2-like OS=Cricetulus griseus OX=10029 GN=LOC100770111 PE=3 SV=1 CANONICAL=A0A9J7H422-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H422", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H422" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H422", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H422" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770111", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770111", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "deSUMOylase activity", "id": "GO:0016929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016929", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H422", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H422" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H422", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H422" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H422", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H422" } ], "pmid": "" }, { "name": "protein desumoylation", "id": "GO:0016926", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016926", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H422", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H422" } ], "pmid": "" }, { "name": "regulation of primary metabolic process", "id": "GO:0080090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080090", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H422", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H422" } ], "pmid": "" }, { "name": "regulation of macromolecule metabolic process", "id": "GO:0060255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060255", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H422", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H422" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H422" }, { "id": "PS50600", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50600" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like protease family profile", "eco_id": "ECO_0000259", "start_pos": 300, "end_pos": 464, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 419, "end_pos": 421 }, { "start_pos": 449, "end_pos": 451 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H437-1", "uniprot_ac": "A0A9J7H437", "uniprot_id": "A0A9J7H437_CRIGR", "mass": { "chemical_mass": 103335.0, "monoisotopic_mass": 103335.0 }, "refseq": { "ac": "XP_035305174", "name": "zinc finger protein 566 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305174" }, "gene_names": [ { "name": "Znf566", "type": "recommended", "evidence": [ { "id": "A0A9J7H437", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H437" } ] }, { "name": "Znf566", "type": "synonym", "evidence": [ { "id": "XP_035305174", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305174" } ] } ], "protein_names": [ { "name": "Zinc finger protein 566", "type": "recommended", "evidence": [ { "id": "A0A9J7H437", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H437/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 566 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305174", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305174" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 11% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305174", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305174" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H437", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H437#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H437", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H437" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf566", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H437", "locus": {} } ], "crossref": [ { "id": "A0A9J7H437", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H437", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "103158574", "url": "https://www.ncbi.nlm.nih.gov/gene/103158574", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103158574", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103158574", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H437", "url": "https://www.orthodb.org/?gene=A0A9J7H437", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF248", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF248", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305174", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305174", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H437", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H437", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H437-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H437-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLESLHPESGLLHDELSPGEKLYECNECSETFSLKQTFVEHKKTHSGEKSHECPECGKSFSRVSSLTLHLRSHARRKSCRYSKCGKAFSQRGNFLSHQKQHTEEKPCDSEKTSIPMTPVVKNQTNAGNKPFACKECGKAFNGKSYLKEHEKIHTGEKPFECNQCGRAFSQKQYLIKHQNIHSGKKPFKCNECGKAFSQKENLIIHQRIHTGEKPYECKGCGKAFIQKSSLIRHQRSHTGEKPYTCKECGKAFSGKSNLTEHEKIHVGEKPYKCNECGTIFRQKQYLIKHHNIHTGEKPYECNKCGKAFSRITSLIVHVRIHTGDKPYECKICGKAFCQSSSLTVHLRSHTGEKPYGCSECGKAFSQFSTLALHMRIHTGEKPYQCSECGKAFSQKSHHIRHQKIHIHYPARIEIPPIGSHLVRGVVSDSISQKPPRLLAGKSRSGGTSELGGHLLRRSEGLRGLGRLRARRRAIGAEGGAGRAPSPEPRAPSPEPRARAPSRFVRRGAERSCDYQAMAQVSVLFRDVYIDFSQEEWECLTEEQRDLYRDVMLENYSNLLSMVLESRCEAQKLFLKKELYEIESAQWEIMRKLTRQDLQCPSLSGAWEWSGQCARRHGSQERQFSELVISREDTPTLSQYPSFRLQQILKNKEKYCASKENRKRYKHASRFTTHQIIRTIEKPYECKDCGKTFRHPSGLTHHHKIHTGKKPFECKECGKTFICGSDLTRHHRIHTGEKPYECKDCGKAFSSGSNFTRHQRIHTGEKPYECKECGKAFSSGSNFTQHQRIHTGEKPYECKECGNAFSQSSQLIKHQRIHTGEKPYECKECEKAFRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLISHHRIHAGKKAYKYEDCGKNFNYDSQLIQHQNIYW", "length": 902, "header": "tr|A0A9J7H437-1|A0A9J7H437_CRIGR Isoform 1 of Zinc finger protein 566 OS=Cricetulus griseus OX=10029 GN=Znf566 PE=3 SV=1 CANONICAL=A0A9J7H437-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H437-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H437/entry#A0A9J7H437-1", "sequence": { "sequence": 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"name": "Zinc finger protein 45 isoform X7", "type": "synonym", "evidence": [ { "id": "A0A9J7H472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H472/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 45 isoform X7", "type": "synonym", "evidence": [ { "id": "XP_035305227", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305227" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305227" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K1Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1Q6#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A9J7H472", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H472#function" }, { "database": "UniProtKB", "id": "A0A9J7H566", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H566#function" }, { "database": "UniProtKB", "id": "A0A9J7H7A6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A6#function" }, { "database": "UniProtKB", "id": "A0A061HTL7", "url": "https://www.uniprot.org/uniprotkb/A0A061HTL7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H472", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H472" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100767782", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H472", "locus": {} } ], "crossref": [ { "id": "A0A9J7H472", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H472", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767782", "url": "https://www.ncbi.nlm.nih.gov/gene/100767782", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767782", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767782", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H472", "url": "https://www.orthodb.org/?gene=A0A9J7H472", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226:SF411", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226:SF411", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390:SF264", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390:SF264", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305227", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HTL7", "url": "https://www.uniprot.org/uniprotkb/A0A061HTL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HTL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HTL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H472", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H472", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H472-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H472-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H566", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H566", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H566-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H566-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7A6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K1Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1Q6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K1Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1Q6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKVKEMVTFRDVAVVFSEEELVLLDAAQRKLYRDVMLETFKNVVSLGHQIMTPDVLLQLKREDVLWMLMMAGWSRESTGARNPDGMESLQEVGWRYLPHQEPFCSRIRHQVSRALTQAGDCTGSTGEAGSPLGKQDAVQREEAGFSKHSGRDSRLPLHCGMSGGEEPYREEMMGKGSHWDRPLQAKGPAHAGEKRYKCESCDNSFCRLSGLQAHQARHTGEKPYKCEECGKSFTRASTLLDHQRGHTGNKPYQCHACWKSFCHSSEFNNHLRVHTGEKPYVCEECGKGFSQASHLLAHQRGHTGEKPYKCGTCGKGFSRSSDLNVHCRIHTGEKPYKCERCGKAFSRVSILQVHQRVHSDEKPYQCDACGKGFTVESHLQAHQRSHTGERPYRCEECGRGFCRASNFLAHRGVHTGEKPYRCDLCGKRFRQRSYLHDHHRVHTGEKPYKCGECGKVFSWSSYLKAHQRVHTGEKPYRCEACGKGFSWSSSLLIHQRVHAGERPYACEACGSAFSQASHLQDHQRLHTGEKPFKCDTCGKSFSRNSHLRSHHRVHTGEKPYKCEECGKSFICSSNLYIHQRVHTGEKPYKCVDCGKEFSRPSSLQAHQGIHTGEKSYVCTVCGKGYTLNSNLQVHLRVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEVCGKSFGWRSNLLIHHRIHSSSRPSKSARDGKNIKESVQEKRSIK", "length": 721, "header": "tr|A0A9J7H472-1|A0A9J7H472_CRIGR Isoform 1 of Zinc finger protein 45 isoform X7 OS=Cricetulus griseus OX=10029 GN=LOC100767782 PE=3 SV=1 CANONICAL=A0A9J7H472-1" }, "isoforms": [ { "isoform_ac": "A0A061HTL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H472/entry#A0A061HTL7-1", "sequence": { "sequence": "MESLQEVGWRYLPHQEPFCSRIRHQVSRALTQAGDCTGSTGEAGSPLGKQDAVQREEAGFSKHSGRDSRLPLHCGMSGGEEPYREEMMGKGSHWDRPLQAKGPAHAGEKRYKCESCDNSFCRLSGLQAHQARHTGEKPYKCEECGKSFTRASTLLDHQRGHTGNKPYQCHACWKSFCHSSEFNNHLRVHTGEKPYVCEECGKGFSQASHLLAHQRGHTGEKPYKCGTCGKGFSRSSDLNVHCRIHTGEKPYKCERCGKAFSRVSILQVHQRVHSDEKPYQCDACGKGFTVESHLQAHQRSHTGERPYRCEECGRGFCRASNFLAHRGVHTGEKPYRCDLCGKRFRQRSYLHDHHRVHTGEKPYKCGECGKVFSWSSYLKAHQRVHTGEKPYRCEACGKGFSWSSSLLIHQRVHADHEGCRDFPAPEVSPRKHAL", "length": 434, "header": "tr|A0A061HTL7-1|A0A061HTL7_CRIGR Computationally mapped isoform of Zinc finger protein 45 isoform X6 OS=Cricetulus griseus OX=10029 GN=LOC100767782 PE=3 SV=1 CANONICAL=A0A9J7H472-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H472-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H472/entry#A0A9J7H472-1", "sequence": { "sequence": "MTKVKEMVTFRDVAVVFSEEELVLLDAAQRKLYRDVMLETFKNVVSLGHQIMTPDVLLQLKREDVLWMLMMAGWSRESTGARNPDGMESLQEVGWRYLPHQEPFCSRIRHQVSRALTQAGDCTGSTGEAGSPLGKQDAVQREEAGFSKHSGRDSRLPLHCGMSGGEEPYREEMMGKGSHWDRPLQAKGPAHAGEKRYKCESCDNSFCRLSGLQAHQARHTGEKPYKCEECGKSFTRASTLLDHQRGHTGNKPYQCHACWKSFCHSSEFNNHLRVHTGEKPYVCEECGKGFSQASHLLAHQRGHTGEKPYKCGTCGKGFSRSSDLNVHCRIHTGEKPYKCERCGKAFSRVSILQVHQRVHSDEKPYQCDACGKGFTVESHLQAHQRSHTGERPYRCEECGRGFCRASNFLAHRGVHTGEKPYRCDLCGKRFRQRSYLHDHHRVHTGEKPYKCGECGKVFSWSSYLKAHQRVHTGEKPYRCEACGKGFSWSSSLLIHQRVHAGERPYACEACGSAFSQASHLQDHQRLHTGEKPFKCDTCGKSFSRNSHLRSHHRVHTGEKPYKCEECGKSFICSSNLYIHQRVHTGEKPYKCVDCGKEFSRPSSLQAHQGIHTGEKSYVCTVCGKGYTLNSNLQVHLRVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEVCGKSFGWRSNLLIHHRIHSSSRPSKSARDGKNIKESVQEKRSIK", "length": 721, "header": "tr|A0A9J7H472-1|A0A9J7H472_CRIGR Isoform 1 of Zinc finger protein 45 isoform X7 OS=Cricetulus griseus OX=10029 GN=LOC100767782 PE=3 SV=1 CANONICAL=A0A9J7H472-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H566-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H472/entry#A0A9J7H566-1", "sequence": { "sequence": "MTPDVLLQLKREDVLWMLMMAGWSRESTGARNPDGMESLQEVGWRYLPHQEPFCSRIRHQVSRALTQAGDCTGSTGEAGSPLGKQDAVQREEAGFSKHSGRDSRLPLHCGMSGGEEPYREEMMGKGSHWDRPLQAKGPAHAGEKRYKCESCDNSFCRLSGLQAHQARHTGEKPYKCEECGKSFTRASTLLDHQRGHTGNKPYQCHACWKSFCHSSEFNNHLRVHTGEKPYVCEECGKGFSQASHLLAHQRGHTGEKPYKCGTCGKGFSRSSDLNVHCRIHTGEKPYKCERCGKAFSRVSILQVHQRVHSDEKPYQCDACGKGFTVESHLQAHQRSHTGERPYRCEECGRGFCRASNFLAHRGVHTGEKPYRCDLCGKRFRQRSYLHDHHRVHTGEKPYKCGECGKVFSWSSYLKAHQRVHTGEKPYRCEACGKGFSWSSSLLIHQRVHADHEGCRDFPAPEVSPRKHAL", "length": 469, "header": "tr|A0A9J7H566-1|A0A9J7H566_CRIGR Computationally mapped isoform of Zinc finger protein 45 isoform X5 OS=Cricetulus griseus OX=10029 GN=LOC100767782 PE=3 SV=1 CANONICAL=A0A9J7H472-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H472/entry#A0A9J7H7A6-1", "sequence": { "sequence": "MSTHKETVTFKDVAVAFTEEELKLLDSAQRKLYQEVMVENFRNLLSVGINNQTELRAVQDGRSREALSCWQIWQRVMDDLTRCQDSVVTTSQLQGDSPCRVRRGLSAHVSEDENAIQSQKAKVPIDAGRPVLPTLRTQGSWQKNFLTEPQRPKNGYQAISSRSERGRISHSHSDRRAHKSKDSHSPSGYGKESIKAAASFGQSRATQAGQRNDGYAALSSFAPHRLSAGDRSCSCVECGQDSHQGTDGCAGRVGERHQGFGRNPLPRSHQKVTTEARPYECERCGKFFRCRSALNVHFKVHTRERPYACEACGSAFSQASHLQDHQRLHTGEKPFKCDTCGKSFSRNSHLRSHHRVHTGEKPYKCEECGKSFICSSNLYIHQRVHTGEKPYKCVDCGKEFSRPSSLQAHQGIHTGEKSYVCTVCGKGYTLNSNLQVHLRVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEVCGKSFGWRSNLLIHHRIHSSSRPSKSARDGKNIKESVQEKRSIK", "length": 523, "header": "tr|A0A9J7H7A6-1|A0A9J7H7A6_CRIGR Computationally mapped isoform of Zinc finger protein 226 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100767782 PE=3 SV=1 CANONICAL=A0A9J7H472-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K1Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H472/entry#A0A9J7K1Q6-1", "sequence": { "sequence": "MTKVKEMVTFRDVAVVFSEEELVLLDAAQRKLYRDVMLETFKNVVSLGHQIMTPDVLLQLKREDVLWMLMMAGWSRESTGARNPDGMESLQEVGWRYLPHQEPFCSRIRHQVSRALTQAGDCTGSTGEAGSPLGKQDAVQREEAGFSKHSGRDSRLPLHCGMSGGEEPYREEMMGKGSHWDRPLQAKGPAHAGEKRYKCESCDNSFCRLSGLQAHQARHTGEKPYKCEECGKSFTRASTLLDHQRGHTGNKPYQCHACWKSFCHSSEFNNHLRVHTGEKPYVCEECGKGFSQASHLLAHQRGHTGEKPYKCGTCGKGFSRSSDLNVHCRIHTGEKPYKCERCGKAFSRVSILQVHQRVHSDEKPYQCDACGKGFTVESHLQAHQRSHTGERPYRCEECGRGFCRASNFLAHRGVHTGEKPYRCDLCGKRFRQRSYLHDHHRVHTGEKPYKCGECGKVFSWSSYLKAHQRVHTGEKPYRCEACGKGFSWSSSLLIHQRVHADHEGCRDFPAPEVSPRKHAL", "length": 520, "header": "tr|A0A9J7K1Q6-1|A0A9J7H472_CRIGR Computationally mapped isoform of Zinc finger protein 45 isoform X7 OS=Cricetulus griseus OX=10029 GN=LOC100767782 PE=3 SV=1 CANONICAL=A0A9J7H472-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K1Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1Q6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K1Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1Q6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767782", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767782", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H472", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H472" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H472", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H472" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H472", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H472" } ], "pmid": "" }, { "name": "positive regulation of reciprocal meiotic recombination", "id": "GO:0010845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010845", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H472", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H472" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H472", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H472" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 9, 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"MSAGQRRIMSLLQLFSILLAAVVSGARGWGYYGCNEELVGPLYARSLGASSYYGLFTTARFARLHGISGWSPRIGDPNPWLQIDLMKKHRIRAVATQGAFNSWDWVTRYMLLYGDRVDSWTPFYQQGHNATFFGNVNESAVVRHDLHYHFTARYIRIVPLAWNPRGKIGLRLGIYGCPYKSDILYFDGDDAISYRFPRGVSQSLWDVFAFSFKTEEKDGLLLHTEGAQGDYVTLELQGAHLLLHMSLGSSPIQPRPGHTTVSVGGVLNDLSWHYVRVDRYGREANLTLDGYVHRFVLNGDFERLNLDNEIFIGGLVGAARKNLAYRHNFRGCIENVIYNRINIADLAVQGHSRITFEGNVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRFAVSFRFRTWDLTGLLLYSRLGDGLGHVELMLSEGQVNVSIAQTGRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSSPLLIRTGTSYFFGGCPKPASRWGCHSNQTAFHGCMELLKVDGQLVNLTLVEFRRLGYFAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGVTCHEPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRENRAWTVVRHDRLWTTRVTGSSMDRPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALHCNCDADQPQWRTDKGLLTFVDHLPVTQIVVGDTNRTSSEAQFFLRPLRCYGDRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPFCQWRRPYVRVELNTSRDIVFAFDIGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWLEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTFPNCTGHCTHPRFPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFETGTWMRYNLQSALRSAAQEFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKEDGTLQLRYQLGTSPYVYQLTTRPVTDGQPHSVNITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEAMRVQGELSESNCGAMPRLVSEVPPELDPWYLPPDFPYYHDDGWVAILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNEPKASHDYHPGSKTPLPPSGPAQAPAPTPAPTQVPAPAPAPAPAPAPAPAPASGPGPRDQNLPQILEESRSE", "length": 1399, "header": "tr|A0A9J7H497-1|A0A9J7H497_CRIGR Isoform 1 of Contactin-associated protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Cntnap1 PE=3 SV=1 CANONICAL=A0A9J7H497-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H497-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H497/entry#A0A9J7H497-1", "sequence": { "sequence": "MSAGQRRIMSLLQLFSILLAAVVSGARGWGYYGCNEELVGPLYARSLGASSYYGLFTTARFARLHGISGWSPRIGDPNPWLQIDLMKKHRIRAVATQGAFNSWDWVTRYMLLYGDRVDSWTPFYQQGHNATFFGNVNESAVVRHDLHYHFTARYIRIVPLAWNPRGKIGLRLGIYGCPYKSDILYFDGDDAISYRFPRGVSQSLWDVFAFSFKTEEKDGLLLHTEGAQGDYVTLELQGAHLLLHMSLGSSPIQPRPGHTTVSVGGVLNDLSWHYVRVDRYGREANLTLDGYVHRFVLNGDFERLNLDNEIFIGGLVGAARKNLAYRHNFRGCIENVIYNRINIADLAVQGHSRITFEGNVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRFAVSFRFRTWDLTGLLLYSRLGDGLGHVELMLSEGQVNVSIAQTGRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSSPLLIRTGTSYFFGGCPKPASRWGCHSNQTAFHGCMELLKVDGQLVNLTLVEFRRLGYFAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGVTCHEPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRENRAWTVVRHDRLWTTRVTGSSMDRPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALHCNCDADQPQWRTDKGLLTFVDHLPVTQIVVGDTNRTSSEAQFFLRPLRCYGDRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPFCQWRRPYVRVELNTSRDIVFAFDIGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWLEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTFPNCTGHCTHPRFPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFETGTWMRYNLQSALRSAAQEFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKEDGTLQLRYQLGTSPYVYQLTTRPVTDGQPHSVNITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEAMRVQGELSESNCGAMPRLVSEVPPELDPWYLPPDFPYYHDDGWVAILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNEPKASHDYHPGSKTPLPPSGPAQAPAPTPAPTQVPAPAPAPAPAPAPAPAPASGPGPRDQNLPQILEESRSE", "length": 1399, "header": "tr|A0A9J7H497-1|A0A9J7H497_CRIGR Isoform 1 of Contactin-associated protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Cntnap1 PE=3 SV=1 CANONICAL=A0A9J7H497-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JY27-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H497/entry#A0A9J7JY27-1", "sequence": { "sequence": "MKKHRIRAVATQGAFNSWDWVTRYMLLYGDRVDSWTPFYQQGHNATFFGNVNESAVVRHDLHYHFTARYIRIVPLAWNPRGKIGLRLGIYGCPYKSDILYFDGDDAISYRFPRGVSQSLWDVFAFSFKTEEKDGLLLHTEGAQGDYVTLELQGAHLLLHMSLGSSPIQPRPGHTTVSVGGVLNDLSWHYVRVDRYGREANLTLDGYVHRFVLNGDFERLNLDNEIFIGGLVGAARKNLAYRHNFRGCIENVIYNRINIADLAVQGHSRITFEGNVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRFAVSFRFRTWDLTGLLLYSRLGDGLGHVELMLSEGQVNVSIAQTGRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSSPLLIRTGTSYFFGGCPKPASRWGCHSNQTAFHGCMELLKVDGQLVNLTLVEFRRLGYFAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGVTCHEPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRENRAWTVVRHDRLWTTRVTGSSMDRPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALHCNCDADQPQWRTDKGLLTFVDHLPVTQIVVGDTNRTSSEAQFFLRPLRCYGDRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPFCQWRRPYVRVELNTSRDIVFAFDIGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWLEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTFPNCTGHCTHPRFPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFETGTWMRYNLQSALRSAAQEFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKEDGTLQLRYQLGTSPYVYQLTTRPVTDGQPHSVNITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEAMRVQGELSESNCGAMPRLVSEVPPELDPWYLPPDFPYYHDDGWVAILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNEPKASHDYHPGSKTPLPPSGPAQAPAPTPAPTQVPAPAPAPAPAPAPAPAPASGPGPRDQNLPQILEESRSE", "length": 1314, "header": "tr|A0A9J7JY27-1|A0A9J7H497_CRIGR Computationally mapped isoform of Contactin-associated protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Cntnap1 PE=3 SV=1 CANONICAL=A0A9J7H497-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1355, "start_aa": "Thr", "end_pos": 1355, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1355", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JY27", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JY27" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JY27", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JY27" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751740", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751740", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H497", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H497" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H497", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H497" } ], "pmid": "" }, { "name": "main axon", "id": "GO:0044304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044304", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H497", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H497" } ], "pmid": "" }, { "name": "paranodal junction", "id": "GO:0033010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033010", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H497", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H497" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1087, "end_pos": 1089, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1156, "end_pos": 1158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 527, "end_pos": 529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 606, "end_pos": 608, "annotation": "n_glycosylation_sequon" }, { "start_pos": 662, "end_pos": 664, "annotation": "n_glycosylation_sequon" }, { "start_pos": 673, "end_pos": 675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 772, "end_pos": 774, "annotation": "n_glycosylation_sequon" }, { "start_pos": 813, "end_pos": 815, "annotation": "n_glycosylation_sequon" }, { "start_pos": 852, "end_pos": 854, "annotation": "n_glycosylation_sequon" }, { "start_pos": 869, "end_pos": 871, "annotation": "n_glycosylation_sequon" }, { "start_pos": 957, "end_pos": 959, "annotation": "n_glycosylation_sequon" }, { "start_pos": 965, "end_pos": 967, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H497" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 549, "end_pos": 586, "start_aa": "Ile", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H497" }, { "id": "PS50022", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50022" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F5/8 type C", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 177, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": 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"n_linked_sites": [], "o_linked_sites": [ 1355 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1087, "end_pos": 1089 }, { "start_pos": 1156, "end_pos": 1158 }, { "start_pos": 129, "end_pos": 131 }, { "start_pos": 137, "end_pos": 139 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 429, "end_pos": 431 }, { "start_pos": 508, "end_pos": 510 }, { "start_pos": 527, "end_pos": 529 }, { "start_pos": 606, "end_pos": 608 }, { "start_pos": 662, "end_pos": 664 }, { "start_pos": 673, "end_pos": 675 }, { "start_pos": 772, "end_pos": 774 }, { "start_pos": 813, "end_pos": 815 }, { "start_pos": 852, "end_pos": 854 }, { "start_pos": 869, "end_pos": 871 }, { "start_pos": 957, "end_pos": 959 }, { "start_pos": 965, "end_pos": 967 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { 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"evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4G4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4G4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H4G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4G4" }, { "id": "PF01248", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01248" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribosomal protein eL8/eL30/eS12/Gadd45", "eco_id": "ECO_0000259", "start_pos": 180, "end_pos": 261, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 20, "end_pos": 22 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"Znf454", "type": "recommended", "evidence": [ { "id": "A0A9J7H4K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K1" } ] }, { "name": "Znf454", "type": "synonym", "evidence": [ { "id": "XP_035303262", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303262" } ] } ], "protein_names": [ { "name": "Zinc finger protein 454", "type": "synonym", "evidence": [ { "id": "A0A9J7H4K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K1/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 454", "type": "synonym", "evidence": [ { "id": "XP_035303262", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303262" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613693.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303262", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303262" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K1#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf454", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K1", "locus": {} } ], "crossref": [ { "id": "A0A9J7H4K1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H4K1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768401", "url": "https://www.ncbi.nlm.nih.gov/gene/100768401", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768401", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768401", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H4K1", "url": "https://www.orthodb.org/?gene=A0A9J7H4K1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768401", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768401", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K1" } ], "pmid": "" }, { "name": "regulation of anatomical structure morphogenesis", "id": "GO:0022603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022603", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K1" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H4K2-1", "uniprot_ac": "A0A9J7H4K2", "uniprot_id": "A0A9J7H4K2_CRIGR", "mass": { "chemical_mass": 136415.0, "monoisotopic_mass": 136415.0 }, "refseq": { "ac": "XP_035305424", "name": "nephrin isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305424" }, "gene_names": [ { "name": "Nphs1", "type": "recommended", "evidence": [ { "id": "A0A9J7H4K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K2" } ] }, { "name": "Nphs1", "type": "synonym", "evidence": [ { "id": "XP_035305424", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305424" } ] } ], "protein_names": [ { "name": "Renal glomerulus-specific cell adhesion receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7H4K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K2/entry#names_and_taxonomy" } ] }, { "name": "nephrin isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305424", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305424" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305424", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305424" } ] }, { "annotation": "Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K2#function" }, { "database": "UniProtKB", "id": "ARBA00058919", "url": "https://www.uniprot.org/uniprotkb/ARBA00058919#function" }, { "database": "UniProtKB", "id": "A0A9J7H8X8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8X8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nphs1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K2", "locus": {} } ], "crossref": [ { "id": "A0A9J7H4K2", "url": 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"id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051275", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051275", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773617", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773617", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H4K2", "url": "https://www.orthodb.org/?gene=A0A9J7H4K2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11640", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11640", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11640:SF136", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11640:SF136", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305424", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305424", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H4K2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8X8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8X8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8X8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { 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"MGTKEVSIRGPGVTPIPRTSSLTPWLLMGMLTTGLTLSSIPTSVPRGFWTVSDNLTAVEGTTVKLRCGVSAPGSIVQWAKDGLLLGPNPRIPGFPRYSLEGDPAKGEFHLRIEACDLSDDAEYECQVGRSETGPELLSPKVILSILVPPKVLQLTPEEGSTVTWVAGQEYVVTCVSGDAKPAPDITFIQGGDTILGVSYNVNDGSEEKLFIAEAEARVTPRSSDNGQLLVCAGSSPALDTPIKASFTMNVLFPPGPPVIDWPGLDEGHVRAGQNLELPCVARGGNPPATLQWLKNGKPVAIAWGTEHVQSVARSVLVMTVRPEDQGAQLSCLSYNSVSVETQEQSVTLQVTFPPSAITILGSATQSENKNVTLCCLTKSSRPRVLLRWWLGGRQLQPTDETVMDGLHGGHISMSNLTLLVRREDNGLSLTCEAFSDAFSKETFKKSLTLNVKYPAQKLWIEGPQEGQFIRTGTRVRLVCLAIGGNPDPSLTWLKDSRTVSEPRQPQEPRRVQLGSLEKSGSTFSRELVLVIGPSDNRAKFSCKAGQLSASTQLLVQFPPTNLTILANSSALRPGDALNLTCVSISSNPPVNLSWDKEGERLEDVAAPPQSAPFKGSAASRSVFLRVSSRDHGHRVTCRAHSAALRETVSSFYRLNVLYPPEFLGEQVLAVTAVEQGQALLPVSVSANPAPEAFNWTFRGYRLSPAGGPRHRILSGGALQLWNVTRADDGIYQLHCQNSEGTAEALLKLDVHYAPIIRALRDPTEVNVGGSVDLVCTVDANPILPEMFSWERLGEDEDDLNLDDMEKISKGSTGRLRIHQAKLSQAGAYQCIVDNGVEPAARGLVRLVVRFAPQVDHPTPLTKVAAAGDSTSSATLHCRARGVPNIDFTWTKNGVPLDLQDPRYTEHRYHQGVVHSSLLTIANVSAAQDYALFTCTATNALGSDHTDIQLVSIGRPDPPLGLKVVSVTPNSVGLEWKPGFDGGLPQRFQIRYETLEAPGFLYADVLPPQATTFTLTGLKPSTRYRIWLLASNALGDSGLAHKGIQVSITTPGLDQAPEDTDHPRPTEQPPGAPRLPLLPVLFAVGGLLLLSNACCFGGLLWRRRRRRLAEEISEKTEAGSEEDRVRNEYEESQWTGDRDTGSSVVSTAEVEPHYQSMRDFSPRLPPTLEEVPYPQAFTGVEDEDMAFPGHLYDEVERAYGPPAGWGPLYDEVQMDPYDLRWPEVKYEDPRGIYDQVAADLGAVEPNSLPFELRGHLV", "length": 1256, "header": "tr|A0A9J7H4K2-1|A0A9J7H4K2_CRIGR Isoform 1 of Renal glomerulus-specific cell adhesion receptor OS=Cricetulus griseus OX=10029 GN=Nphs1 PE=3 SV=1 CANONICAL=A0A9J7H4K2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H4K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K2/entry#A0A9J7H4K2-1", "sequence": { "sequence": 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"length": 1256, "header": "tr|A0A9J7H4K2-1|A0A9J7H4K2_CRIGR Isoform 1 of Renal glomerulus-specific cell adhesion receptor OS=Cricetulus griseus OX=10029 GN=Nphs1 PE=3 SV=1 CANONICAL=A0A9J7H4K2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H8X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K2/entry#A0A9J7H8X8-1", "sequence": { "sequence": "MGTKEVSIRGPGVTPIPRTSSLTPWLLMGMLTTGLTLSSIPTSVPRGFWTVSDNLTAVEGTTVKLRCGVSAPGSIVQWAKDGLLLGPNPRIPGFPRYSLEGDPAKGEFHLRIEACDLSDDAEYECQVGRSETGPELLSPKVILSILVPPKVLQLTPEEGSTVTWVAGQEYVVTCVSGDAKPAPDITFIQGGDTILGVSYNVNDGSEEKLFIAEAEARVTPRSSDNGQLLVCAGSSPALDTPIKASFTMNVLFPPGPPVIDWPGLDEGHVRAGQNLELPCVARGGNPPATLQWLKNGKPVAIAWGTEHVQSVARSVLVMTVRPEDQGAQLSCLSYNSVSVETQEQSVTLQVTFPPSAITILGSATQSENKNVTLCCLTKSSRPRVLLRWWLGGRQLQPTDETVMDGLHGGHISMSNLTLLVRREDNGLSLTCEAFSDAFSKETFKKSLTLNVKYPAQKLWIEGPQEGQFIRTGTRVRLVCLAIGGNPDPSLTWLKDSRTVSEPRQPQEPRRVQLGSLEKSGSTFSRELVLVIGPSDNRAKFSCKAGQLSASTQLLVQFPPTNLTILANSSALRPGDALNLTCVSISSNPPVNLSWDKEGERLEDVAAPPQSAPFKGSAASRSVFLRVSSRDHGHRVTCRAHSAALRETVSSFYRLNVLYPPEFLGEQVLAVTAVEQGQALLPVSVSANPAPEAFNWTFRGYRLSPAGGPRHRILSGGALQLWNVTRADDGIYQLHCQNSEGTAEALLKLDVHYAPIIRALRDPTEVNVGGSVDLVCTVDANPILPEMFSWERLGEDEDDLNLDDMEKISKGSTGRLRIHQAKLSQAGAYQCIVDNGVEPAARGLVRLVVRFAPQVDHPTPLTKVAAAGDSTSSATLHCRARGVPNIDFTWTKNGVPLDLQDPRYTEHRYHQGVVHSSLLTIANVSAAQDYALFTCTATNALGSDHTDIQLVSIGRPDPPLGLKVVSVTPNSVGLEWKPGFDGGLPQRFQIRYETLEAPGFLYADVLPPQATTFTLTGLKPSTRYRIWLLASNALGDSGLAHKGIQVSITTPGLDQAPEDTDHPRPTEQPPGAPRLPLLPVLFAVGGLLLLSNACCFGGLLWRRRRRRLAEEISEKTEAGSEEDRVRNEYEESQWTGDRDTGSSVVSTAEVEPHYQSMRDFSPRLPPTLEEVPYPQGVEDEDMAFPGHLYDEVERAYGPPAGWGPLYDEVQMDPYDLRWPEVKYEDPRGIYDQVAADLGAVEPNSLPFELRGHLV", "length": 1253, "header": "tr|A0A9J7H8X8-1|A0A9J7H8X8_CRIGR Computationally mapped isoform of Renal glomerulus-specific cell adhesion receptor OS=Cricetulus griseus OX=10029 GN=Nphs1 PE=3 SV=1 CANONICAL=A0A9J7H4K2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773617", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773617", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K2" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K2" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304609", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304609" } ] }, { "annotation": "Binds to the cAMP response element and activates transcription.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K4#function" }, { "database": "UniProtKB", "id": "PIRNR003153", "url": "https://www.uniprot.org/uniprotkb/PIRNR003153#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Creb5", "url": 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"Protein Classification", "Other" ] }, { "id": "XP_035304609", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304609", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H4K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4K4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNLEQERPFVCSAPGCSQRFPTEDHLMIHRHKHEMTLKFPSIKTDNMLSDQTPTPTRFLKNCEEVGLFSELDCSFEHEFRKAQEEENSKRNISMHNAVGGTMTGPGAHQLGSTRMPNHDTSVVIQQAMPSPQSSSVITQAPSTNRQIGPVPGSLSSLLHLHNRQRQPMPASMPGTLPNPTMPGSSAVLMPMERQMSVNSSIMGMQGPNLSNPCASPQVQPMHSEAKMRLKAALTHHPAAMSNGNMSTIGHMMEMMGSRQDQTQHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHSGNQAQVSPATQQMQPTQTIQPPQPTGGRRRRVVDEDPDERRRKFLERNRAAATRCRQKRKVWVMSLEKKAEELTQTNMQLQNEVSMLKNEVAQLKQLLLTHKDCPITAMQKESQGYLSPESSPPASPVPACSQQPVIQHNTITTSSAVSEVVGSSTLSQLTTHRTDLNPIL", "length": 501, 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"MAVVSVSLLSVSAVTNSSGGLKKELRLAGGENNCSGRVEVKIHEKWGTVCQNNWSMNEVSVVCRQLGCPTSIQALGWPNSSAGSGDIWMDKVSCTGNESALWDCKHEGWGKHNCTHEQDVGVTCSDGSNLEMKLVNDRPNRCLGRVEVKFQGKWGTVCDDNFSKDHATVICKQLGCGSAISFSGSAKFGAGSGPIWLDDLVCDGNESALWDCKHGAWGKHNCDHAEDVGVICLEGADLSLRLADGGSKCSGRLEVRFQDEWGTVCDDSWDALDASVVCKQLGCPAAISLIGRVNTSEGSGQIWLDNVSCKGDEAALWDCKHQEWGKHYCNHREDAGVTCSDGSDLELRLVGGGSRCSGTVEVEIQKLKGNICSRGWTLVDADVVCRQLGCGSALQTSSKIYSKSMATDTWLFPGSCSGNETSLWQCRNWQWGGLSCDHFEEAQVTCSGHREPRLVGGEIPCSGRVEVKHGDVWGSVCDFGLSLEAASVVCRELQCGTVISILGGAHFGEGSGQIWTEEFQCTGNESHLSLCSVAPPLEESCSHSRDVSIVCSRYTEIRLAGGKSSCEGRVEIKVLGAWGPLCNSHWDIEDAHVLCQQLKCGVALSTPGGAHFGKGAGQVWRHMFHCTGTEQHMGDCLVTALGAPVCSEGQVASVICSGNQSQILQPCSSSSSVQTTSSTIPNQSDVPCIASGQVRLVDGGSRCAGRVEVYHEGVWGTICDDSWDLIDASVVCKQLDCGVAINATGSAYFKEGTGNIWLDEINCSGKESQIWQCRSHGWGRHNCRHKEDAGVICSEFMSLRLTNDVPRENCTGHLEVFYNGTWGSVGSSNMSSTTVGVVCRQLGCADSGTLKPTSADKTPSRLMWIDNVQCPKGVDTLWQCPSSPWKQRQASPSEESWIVCDNKVRLQGGHTDCSGRVEIWHKGSWGTVCDDSWDLNDAKVACRQLGCGQAVKALKEAAYGPGTGPIWLNEMRCRGKETSLWDCPAKPWSHSDCGHKEDASIQCLPGAPPKSEQGHSVLVALLICGAILLVLVIAFLLWTLKRRQIQRLTVSSRGEISIHQVQYQEMNSRADDLDLLKSSENSNDFNADGLTSLSKYLPIPGFKKGSNSEEH", "length": 1111, "header": "tr|A0A9J7H4M0-1|A0A9J7H4M0_CRIGR Isoform 1 of Scavenger receptor cysteine-rich type 1 protein M130 OS=Cricetulus griseus OX=10029 GN=Cd163 PE=4 SV=1 CANONICAL=A0A9J7H4M0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H4M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M0/entry#A0A9J7H4M0-1", "sequence": { "sequence": 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"length": 1111, "header": "tr|A0A9J7H4M0-1|A0A9J7H4M0_CRIGR Isoform 1 of Scavenger receptor cysteine-rich type 1 protein M130 OS=Cricetulus griseus OX=10029 GN=Cd163 PE=4 SV=1 CANONICAL=A0A9J7H4M0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768770", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768770", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "acute-phase response", "id": "GO:0006953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006953", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4M0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4M0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, 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{ "ac": "XP_035304943", "name": "sperm motility kinase-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304943" }, "gene_names": [ { "name": "LOC113837096", "type": "recommended", "evidence": [ { "id": "A0A9J7H4N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5" } ] }, { "name": "LOC113837096", "type": "synonym", "evidence": [ { "id": "XP_035304943", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304943" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A9J7H4N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A9J7H4N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5/entry#names_and_taxonomy" } ] }, { "name": "sperm motility kinase-like", "type": "synonym", "evidence": [ { "id": "XP_035304943", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304943" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304943", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304943" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113837096", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5", "locus": {} } ], "crossref": [ { "id": "A0A9J7H4N5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H4N5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14337", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14337", "database": "CDD", "categories": [ "Protein 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304943", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304943", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H4N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVTVHSQREPVNKDLIMEQGREVCYSCEESFMTDDKMMMSVGHGHFSEMKLAFHVPTVTCAAVKVLRMKKKNASLVEVSIMKSLQHPDIIKLFGMVQSRDTTYLMMEHTSQGDLRHILELGSLQESEARRLFTQILLAMQYCHANHIAHRDIKANNILLNCRGNAKLSGFDLAAKVTPGQKLRDFCSTLLYCAPELLLEKAYDGCAADIWSLGVLLFLMVVGHFPFQDSSSEGVRRQILAANVRIPEHVSRDIFNVIVKMLMIKPHRRPTVDQILMCPMIREGKPHSPPVSTQKHPGTVSRSIVSTMTVMGYKSEEIIDSLRDQKYDQVMATYPILQHQSPGGDCGLEATNKEVSVTKEVTITKEAAIIQDPTITQEEDMAHEVTMTLEKTTTKEMTMDDGVSMTQTESITEEETIIKHEDIILEATITMEETVAQLRTLTQERTITQEEAITHGQPEDALTRERTITQEDTTTKHEDIILEATITMEETVAHLRTLTRERTITQEEAITHGQPEDALTRERTITEEETITHGQPEDALTQERTITQEEAITHGQPEDAGPASSGNRRRSGWKRVKKIMVNCLRHLCCCCLPPAKRRQDSCKTLAPKTRDPAVTHRSSSEEVQPQLRGL", "length": 629, "header": "tr|A0A9J7H4N5-1|A0A9J7H4N5_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=LOC113837096 PE=4 SV=1 CANONICAL=A0A9J7H4N5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H4N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5/entry#A0A9J7H4N5-1", "sequence": { "sequence": "MVTVHSQREPVNKDLIMEQGREVCYSCEESFMTDDKMMMSVGHGHFSEMKLAFHVPTVTCAAVKVLRMKKKNASLVEVSIMKSLQHPDIIKLFGMVQSRDTTYLMMEHTSQGDLRHILELGSLQESEARRLFTQILLAMQYCHANHIAHRDIKANNILLNCRGNAKLSGFDLAAKVTPGQKLRDFCSTLLYCAPELLLEKAYDGCAADIWSLGVLLFLMVVGHFPFQDSSSEGVRRQILAANVRIPEHVSRDIFNVIVKMLMIKPHRRPTVDQILMCPMIREGKPHSPPVSTQKHPGTVSRSIVSTMTVMGYKSEEIIDSLRDQKYDQVMATYPILQHQSPGGDCGLEATNKEVSVTKEVTITKEAAIIQDPTITQEEDMAHEVTMTLEKTTTKEMTMDDGVSMTQTESITEEETIIKHEDIILEATITMEETVAQLRTLTQERTITQEEAITHGQPEDALTRERTITQEDTTTKHEDIILEATITMEETVAHLRTLTRERTITQEEAITHGQPEDALTRERTITEEETITHGQPEDALTQERTITQEEAITHGQPEDAGPASSGNRRRSGWKRVKKIMVNCLRHLCCCCLPPAKRRQDSCKTLAPKTRDPAVTHRSSSEEVQPQLRGL", "length": 629, "header": "tr|A0A9J7H4N5-1|A0A9J7H4N5_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=LOC113837096 PE=4 SV=1 CANONICAL=A0A9J7H4N5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 177, "start_aa": "Thr", "end_pos": 177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr177", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113837096", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837096", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5" } ], "pmid": "" }, { "name": "tau-protein kinase activity", "id": "GO:0050321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050321", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", 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"A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3E2-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7F9C4-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2M7I3-1", "A0A8C2N3I1-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A9J7JQZ1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A3L7I1E7-1", "A0A9J7GBL6-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7H540-1", "A0A9J7H949-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H8W5-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GQY0-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7JPF2-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K3L1-1", "A0A9J7K6R5-1", "A0A9J7KB54-1", "A0A9J7K851-1", "A0A9J7KCM5-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7JA07-1", "A0A3L7HMX8-1", "A0A061HZ27-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2MP62-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "A0A9J7JYC5-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3HX91-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", "A0A8C2QND0-1", "G3HXQ8-1", "A0A8C2M0A2-1", "A0A9J7K2S5-1", "A0A8C2MMZ5-1", "A0A8C2QH69-1", "A0A8C2QL63-1", "A0A9J7K953-1", "A0A9J7JBH0-1", "A0A9J7FEY2-1", "A0A9J7FGD3-1", "A0A9J7FKM1-1", "A0A9J7JKJ1-1", "A0A9J7G3C1-1", "A0A9J7G180-1", "A0A9J7JTL3-1", "A0A9J7GFS3-1", "A0A9J7GQ42-1", "A0A9J7EZ53-1", "A0A9J7J5Z8-1", "A0A9J7F0G6-1", "A0A9J7FCC7-1", "A0A9J7EVK4-1", "A0A9J7K3S4-1", "A0A9J7GAF4-1", "A0A9J7GBF4-1", "A0A8C2MTI7-1", "A0A9J7J1N3-1", "A0A9J7F4P4-1", "A0A9J7JNU2-1", "A0A9J7H3M5-1", "A0A9J7JJV6-1", "A0A9J7GJE4-1", "A0A8C2LY52-1", "A0A9J7H8U3-1", "A0A9J7F821-1", "A0A8C2N185-1", "A0A9J7KFV8-1", "A0A8C2MQM0-1", "A0A8C2N310-1", "A0A9J7H6V8-1", "A0A9J7H2P9-1", "A0A9J7H4N5-1", "A0A3L7GPC7-1", "A0A9J7J6H1-1", "A0A3L7HV37-1", "A0A8C2LTZ7-1", "A0A9J7K7D8-1", "A0A9J7JXM2-1", "A0A8C2LDU9-1", "A0A8C2LTW4-1", "A0A9J7JAM4-1", "A0A9J7JRJ8-1", "A0A8C2QEB8-1", "A0A3L7HKC4-1", "A0A8C2LI14-1", "A0A8C2QDX9-1", "A0A9J7G1D9-1", "A0A9J7F985-1", "A0A9J7G270-1", "A0A9J7K1H4-1", "A0A8C2MCX3-1", "A0A8C2MEU5-1", "A0A8C2MFN1-1", "A0A8C2MMI4-1", "A0A9J7JAB2-1", "A0A9J7G969-1", "A0A8C2MQ42-1", "A0A8C2MR08-1", "A0A8C2MUQ5-1", "A0A9J7FZA7-1", "A0A8C2N3C9-1", "A0A8C2N6L4-1", "A0A8C2N9X1-1", "A0A8C2QHF9-1", "A0A8C2QI80-1", "A0A8C2QKP7-1", "A0A9J7FFS7-1", "A0A9J7FI14-1", "A0A9J7FJ23-1", "A0A9J7JLH7-1", "A0A8C2MH43-1", "A0A9J7FZ18-1", "A0A9J7G368-1", "A0A9J7G6S5-1", "A0A9J7H2T6-1", "A0A9J7H3N1-1", "A0A9J7H8L4-1", "A0A9J7JIW6-1", "A0A9J7JRI3-1", "A0A061ILI7-1", "A0A061HUS7-1", "A0A061HVM6-1", "A0A061I033-1", "A0A061I8L6-1", "A0A061I9F9-1", "A0A8C2MQS3-1", "A0A9J7F0Y2-1", "A0A9J7EZ49-1", "A0A8C2M6A3-1", "A0A8C2MQL9-1", "A0A8C2LY02-1", "A0A8C2LZT2-1", "A0A8C2M165-1", "A0A8C2M5G2-1", "A0A8C2M3Y9-1", "A0A8C2M5A7-1", "A0A8C2M9B6-1", "A0A8C2MBW2-1", "A0A9J7JYU7-1", "A0A8C2MJ02-1", "A0A8C2ML15-1", "A0A9J7JQD1-1", "A0A8C2MMQ4-1", "A0A8C2MQ73-1", "A0A9J7KE81-1", "A0A9J7JPE2-1", "A0A9J7F773-1", "A0A8C2L7R1-1", "A0A8C2LHE9-1", "A0A3L7I870-1", "A0A3L7IB60-1", "A0A3L7IBX6-1", "A0A3L7ID00-1", "A0A3L7IEL5-1", "A0A3L7IER1-1", "A0A8C2LC89-1", "A0A8C2LCN7-1", "A0A8C2LEI8-1", "A0A8C2LH99-1", "A0A9J7GAB0-1", "A0A8C2LK72-1", "A0A8C2LMC9-1", "A0A8C2LMJ0-1", "A0A9J7JQV6-1", "A0A8C2LPR4-1", "A0A8C2LQB2-1", "A0A8C2LVV5-1", "A0A8C2MYH0-1", "A0A8C2MV78-1", "A0A9J7JHJ2-1", "A0A8C2N0J6-1", "A0A8C2N210-1", "A0A8C2N457-1", "A0A8C2N4W2-1", "A0A8C2N756-1", "A0A8C2QGY5-1", "A0A8C2QJ34-1", "A0A8C2QJA4-1", "A0A9J7KDV7-1", "A0A8C2QNX2-1", "A0A8C2QPB0-1", "A0A9J7EVN3-1", "A0A9J7F0N6-1", "A0A8C2M6E6-1", "A0A9J7F2L0-1", "A0A9J7F3R3-1", "A0A9J7F5B0-1", "A0A8C2LDE5-1", "A0A9J7JB60-1", "A0A9J7F927-1", "A0A9J7F8V5-1", "A0A9J7F8T0-1", "A0A9J7FBT0-1", "A0A9J7FD79-1", "A0A9J7FLY5-1", "A0A9J7K2Q7-1", "A0A3L7I1R2-1", "A0A9J7FYY3-1", "A0A9J7GBI2-1", "A0A9J7FN68-1", "A0A9J7FNF0-1", "A0A9J7FS53-1", "A0A9J7FUL0-1", "A0A9J7FVR6-1", "A0A9J7FZH7-1", "A0A9J7FZW1-1", "A0A9J7G1H0-1", "A0A9J7G5F3-1", "A0A9J7G5N9-1", "A0A8C2LFT9-1", "A0A9J7G9D1-1", "A0A8C2MB66-1", "A0A9J7GD76-1", "A0A8C2LQS5-1", "A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GT89-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JIF8-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7F9C4-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A8C2M7I3-1", "A0A8C2MBI9-1", "A0A9J7JQZ1-1", "A0A8C2N3I1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7GBL6-1", "A0A9J7H8W5-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7H540-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H949-1", "A0A9J7GQY0-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] } ] }, { "uniprot_ac": "A0A8C2M3Y9", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] } ] }, { "uniprot_ac": "A0A8C2M497", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] } ] }, { "uniprot_ac": "A0A8C2QI80", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] } ] }, { "uniprot_ac": "A0A8C2QIA1", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] } ] }, { "uniprot_ac": "A0A8C2QJ34", "gene_name": "Oxsr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] } ] }, { "uniprot_ac": "A0A8C2QJA4", "gene_name": "Pak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJA4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] } ] }, { "uniprot_ac": "A0A8C2QLT0", "gene_name": "Nek9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] } ] }, { "uniprot_ac": "A0A8C2QMB3", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] } ] }, { "uniprot_ac": "A0A8C2QND0", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] } ] }, { "uniprot_ac": "A0A8C2QNX2", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] } ] }, { "uniprot_ac": "A0A8C2QPB0", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] } ] }, { "uniprot_ac": "A0A9J7EUQ5", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] } ] }, { "uniprot_ac": "A0A9J7EVK4", "gene_name": "Bmp2k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] } ] }, { "uniprot_ac": "A0A9J7EVN3", "gene_name": "LOC100754361", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] } ] }, { "uniprot_ac": "A0A9J7EXX8", "gene_name": "LOC113832238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] } ] }, { "uniprot_ac": "A0A9J7F0J6", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": 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} ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F821", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] } ] }, { "uniprot_ac": "A0A9J7GIN7", "gene_name": "Eif2ak3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] } ] }, { "uniprot_ac": "A0A9J7GJE4", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] } ] }, { "uniprot_ac": "A0A9J7GK55", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] } ] }, { "uniprot_ac": "A0A9J7GLT3", "gene_name": "LOC113838166", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] } ] }, { "uniprot_ac": "A0A9J7GMF3", "gene_name": "LOC103158537", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] } ] }, { "uniprot_ac": "A0A9J7GMK5", "gene_name": "Sbk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] } ] }, { "uniprot_ac": "A0A9J7GP29", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] } ] }, { "uniprot_ac": "A0A9J7GQ42", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] } ] }, { "uniprot_ac": "A0A9J7GQY0", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] } ] }, { "uniprot_ac": "A0A9J7GR05", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] } ] }, { "uniprot_ac": "A0A9J7GR29", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] } ] }, { "uniprot_ac": "A0A9J7GRB5", "gene_name": "LOC113838167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRB5" } ] } ] }, { "uniprot_ac": "A0A9J7GRC1", "gene_name": "LOC100764806", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRC1" } ] } ] }, { "uniprot_ac": "A0A9J7GT89", "gene_name": "LOC100774420", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] } ] }, { "uniprot_ac": "A0A9J7GTU0", "gene_name": "LOC100757707", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTU0" } ] } ] }, { "uniprot_ac": "A0A9J7GVC9", "gene_name": "LOC100759146", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVC9" } ] } ] }, { "uniprot_ac": "A0A9J7GX76", "gene_name": "Dapk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GX76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GX76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX76" } ] } ] }, { "uniprot_ac": "A0A9J7GY39", "gene_name": "Akt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] } ] }, { "uniprot_ac": "A0A9J7GZH5", "gene_name": "Ripk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GZH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GZH5", "database": "UniProtKB", "url": 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{ "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": 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This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304836" } ] }, { "annotation": "Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4U4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4U4#function" }, { "database": "UniProtKB", "id": "RU364016", "url": "https://www.uniprot.org/uniprotkb/RU364016#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4U4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4U4" } ], "common_name": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07691", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07691", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304836", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20493", "url": "https://www.rhea-db.org/rhea/20493", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H4U4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4U4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 990, "header": "tr|A0A9J7H4U4-1|A0A9J7H4U4_CRIGR Isoform 1 of Beta-1,4-N-acetylgalactosaminyltransferase OS=Cricetulus griseus OX=10029 GN=B4galnt3 PE=3 SV=1 CANONICAL=A0A9J7H4U4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4U4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4U4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4U4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4U4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756528", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756528", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4U4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4U4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "chondroitin sulfate proteoglycan biosynthetic process", "id": "GO:0050650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050650", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4U4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4U4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "N-acetyl-beta-glucosaminyl-derivative 4-beta-N-acetylgalactosaminyltransferase activity", "id": "GO:0033842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033842", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4U4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4U4" } ], "pmid": "" }, { "name": "glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity", "id": "GO:0047238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047238", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4U4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4U4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" }, { "start_pos": 771, "end_pos": 773, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20493", "name": "", "equation": "an N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-galactosamine = an N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7H4U4-1", "A0A9J7GTD4-1" ], "evidence": [ { "id": "20493", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20493" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7GTD4", "gene_name": "B4galnt4", "activity": [ { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4U4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H4U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4U4" }, { "id": "PS51820", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51820" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PA14", "eco_id": "ECO_0000259", "start_pos": 117, "end_pos": 279, "start_aa": "Glu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.244", "ec_name": "an N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-galactosamine = an N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+).", "evidence": [ { "id": "2.4.1.244", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.244" }, { "id": "2.4.1.244", 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Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. 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bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305608", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305608" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H4Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4Y5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100766779", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4Y5", "locus": {} } ], "crossref": [ { "id": "A0A9J7H4Y5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H4Y5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100766779", "url": "https://www.ncbi.nlm.nih.gov/gene/100766779", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043540", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043540", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766779", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766779", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H4Y5", "url": "https://www.orthodb.org/?gene=A0A9J7H4Y5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46076", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46076", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46076:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46076:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305608", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305608", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H4Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEESVNNAKSLAQPNLRGTESQAASESTMSQAIQSCEVYLVNETSEESIQELPGTSQGIPSNVFVASSGPSWNNFMCPICLDTLKNTRITRDCFHRFCKDCIITALRRGNKECPVCRRKLISKRSLDSDPQLDALIKKMYPSSKEKEAPEEKALGKKKNKTQQEPSVIIETRREIDSIHSVHQGEKKQIETSTGWEDNPGSSPCNIASTHSSESDKASPVNKRAKSSGPEDDSNYVIVTTDPVTDTANEYESSLHATVRGIENPAQTGGKKSSGKLKKRRI", "length": 281, "header": "tr|A0A9J7H4Y5-1|A0A9J7H4Y5_CRIGR Isoform 1 of E3 ubiquitin-protein ligase RING2 OS=Cricetulus griseus OX=10029 GN=LOC100766779 PE=4 SV=1 CANONICAL=A0A9J7H4Y5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H4Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4Y5/entry#A0A9J7H4Y5-1", "sequence": { "sequence": "MEESVNNAKSLAQPNLRGTESQAASESTMSQAIQSCEVYLVNETSEESIQELPGTSQGIPSNVFVASSGPSWNNFMCPICLDTLKNTRITRDCFHRFCKDCIITALRRGNKECPVCRRKLISKRSLDSDPQLDALIKKMYPSSKEKEAPEEKALGKKKNKTQQEPSVIIETRREIDSIHSVHQGEKKQIETSTGWEDNPGSSPCNIASTHSSESDKASPVNKRAKSSGPEDDSNYVIVTTDPVTDTANEYESSLHATVRGIENPAQTGGKKSSGKLKKRRI", "length": 281, "header": "tr|A0A9J7H4Y5-1|A0A9J7H4Y5_CRIGR Isoform 1 of E3 ubiquitin-protein ligase RING2 OS=Cricetulus griseus OX=10029 GN=LOC100766779 PE=4 SV=1 CANONICAL=A0A9J7H4Y5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303624", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303624" } ] }, { "annotation": "RNA-binding protein that regulates alternative splicing events.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M5T2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5T2#function" }, { "database": "UniProtKB", "id": "PIRNR037932", "url": "https://www.uniprot.org/uniprotkb/PIRNR037932#function" }, { "database": "UniProtKB", "id": "A0A9J7K827", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K827#function" }, { "database": "UniProtKB", "id": "A0A9J7H2Q2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q2#function" }, { "database": "UniProtKB", "id": "A0A9J7H3Q7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3Q7#function" }, { "database": "UniProtKB", "id": "A0A9J7H4Y3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4Y3#function" }, { "database": 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"MQHPLTGATCVALPNVGMCPQLSCALTFMYLQQGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPDHTLNLYPPTQTHSEQNADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPDFYAVPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDRNQFVFVATDEISCNTSAVTDEFMLPTPTTTHLLQPPPTALVPCPKVPAPAQTSEELSCTLPGLCCQAAENLPASPPLLQFMFKVIVAQERK", "length": 419, "header": "tr|A0A9J7H4Y3-1|A0A9J7H5Q6_CRIGR Computationally mapped isoform of RNA binding protein fox-1 homolog OS=Cricetulus griseus OX=10029 GN=Rbfox1 PE=4 SV=1 CANONICAL=A0A9J7H5Q6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H5Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Q6/entry#A0A9J7H5Q6-1", "sequence": { "sequence": 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"MLASQGVLLHSYGVPMIVPAAPYFPGLMQGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPDHTLNLYPPTQTHSEQNADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPDFYAGTVLLCQANQEGSSMYSGPSSLVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQEPVYGNKLLQGGYAAYRYAQPTPATAAAYSDSYGRVYAADPYHHTLAPAPTYGVGAMASIYRGGYNRFAPY", "length": 391, "header": "tr|A0A9J7H6U3-1|A0A9J7H6U3_CRIGR Computationally mapped isoform of RNA binding protein fox-1 homolog OS=Cricetulus griseus OX=10029 GN=Rbfox1 PE=4 SV=1 CANONICAL=A0A9J7H5Q6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K827-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Q6/entry#A0A9J7K827-1", "sequence": { "sequence": "MAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPDHTLNLYPPTQTHSEQNADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPDFYAGTVLLCQANQEGSSMYSGPSSLVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDSYGRVYAADPYHHTLAPAPTYGVGAMNAFAPLTDAKTRSHADDVGLVLSSLQASIYRGGYNRFAPY", "length": 376, "header": "tr|A0A9J7K827-1|A0A9J7H5Q6_CRIGR Computationally mapped isoform of RNA binding protein fox-1 homolog OS=Cricetulus griseus OX=10029 GN=Rbfox1 PE=4 SV=1 CANONICAL=A0A9J7H5Q6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 121, "start_aa": "Thr", "end_pos": 121, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr121", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 345, "start_aa": "Thr", "end_pos": 345, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr345", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M5T2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5T2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M5T2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5T2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766551", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766551", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nuclear stress granule", "id": "GO:0097165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Q6" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Q6" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Q6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Q6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Q6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309105", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309105" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBY2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Il17f", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBY2", "locus": {} } ], "crossref": [ { "id": "A0A9J7HBY2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HBY2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100751004", "url": "https://www.ncbi.nlm.nih.gov/gene/100751004", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010345", 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027250093", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250093" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H913", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H913" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Adarb1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H913", "locus": {} } ], "crossref": [ { "id": "cd19895", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19895", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19898", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19898", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755658", "url": "https://www.ncbi.nlm.nih.gov/gene/100755658", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044458", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044458", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044459", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044459", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755658", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755658", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IFSPHES", "url": "https://omabrowser.org/oma/group/IFSPHES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H913", "url": "https://www.orthodb.org/?gene=A0A9J7H913", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10910", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10910", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10910:SF58", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10910:SF58", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02137", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027250093", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250093", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7F4A3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F4A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4A3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H913", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H913", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H913-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H913-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA63-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H8Z3", "url": "https://www.uniprot.org/uniprotkb/G3H8Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H8Z3-1", "url": "https://www.uniprot.org/uniprotkb/G3H8Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MILVSEDWNTTGASSSSTDVKENRNLDNMPPKDSSTPGPVEGIPLSNGGGGSTSRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYMLLSQTGPVHAPLFVMSVEVNGQIFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKSEPPFYVGSNGDDSFSSSGDVSLSASPVPASLTQPPLPIPPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALATVFNLHLDQTPSRQPVLSEGLQLHLPQVLADAVSRLVLGKFSDLTDNFSSPHARRKVLSGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYAQLELYLNNKEDQKKSIFQKSERGGFRLKDTVQFHLYISTSPCGDARIFSPHEPVLEGMTPETHQLTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEIINATTGKDELGRPSRLCKHALYCRWMRVHGKVPPHLLRTKITKPTTYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP", "length": 715, "header": "tr|A0A9J7H913-1|A0A9J7H913_CRIGR Isoform 1 of Double-stranded RNA-specific editase 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Adarb1 PE=4 SV=1 CANONICAL=A0A9J7H913-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F4A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H913/entry#A0A9J7F4A3-1", "sequence": { "sequence": "MDIEDEENMSSSSTDVKENRNLDNMPPKDSSTPGPVEGIPLSNGGGGSTSRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYMLLSQTGPVHAPLFVMSVEVNGQIFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKSEPPFYVGSNGDDSFSSSGDVSLSASPVPASLTQPPLPIPPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALATVFNLHLDQTPSRQPVLSEGLQLHLPQVLADAVSRLVLGKFSDLTDNFSSPHARRKVLSGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYAQLELYLNNKEDQKKSIFQKSERGGFRLKDTVQFHLYISTSPCGDARIFSPHEPVLEGMTPETHQLTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEIINATTGKDELGRPSRLCKHALYCRWMRVHGKVPPHLLRTKITKPTTYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP", "length": 711, "header": "tr|A0A9J7F4A3-1|A0A9J7H913_CRIGR Computationally mapped isoform of Double-stranded RNA-specific editase 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Adarb1 PE=4 SV=1 CANONICAL=A0A9J7H913-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H913-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H913/entry#A0A9J7H913-1", "sequence": { "sequence": "MILVSEDWNTTGASSSSTDVKENRNLDNMPPKDSSTPGPVEGIPLSNGGGGSTSRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYMLLSQTGPVHAPLFVMSVEVNGQIFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKSEPPFYVGSNGDDSFSSSGDVSLSASPVPASLTQPPLPIPPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALATVFNLHLDQTPSRQPVLSEGLQLHLPQVLADAVSRLVLGKFSDLTDNFSSPHARRKVLSGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYAQLELYLNNKEDQKKSIFQKSERGGFRLKDTVQFHLYISTSPCGDARIFSPHEPVLEGMTPETHQLTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEIINATTGKDELGRPSRLCKHALYCRWMRVHGKVPPHLLRTKITKPTTYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP", "length": 715, "header": "tr|A0A9J7H913-1|A0A9J7H913_CRIGR Isoform 1 of Double-stranded RNA-specific editase 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Adarb1 PE=4 SV=1 CANONICAL=A0A9J7H913-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HA63-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H913/entry#A0A9J7HA63-1", "sequence": { "sequence": "MILVSEDWNTTGASSSSTDVKENRNLDNMPPKDSSTPGPVEGIPLSNGGGGSTSRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYMLLSQTGPVHAPLFVMSVEVNGQIFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKSEPPFYVGSNGDDSFSSSGDVSLSASPVPASLTQPPLPIPPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALATVFNLHLDQTPSRQPVLSEGLQLHLPQVLADAVSRLVLGKFSDLTDNFSSPHARRKVLSGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYAQLELYLNNKEDQKKSIFQKSERGGFRLKDTVQFHLYISTSPCGDARIFSPHEPVLEEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEIINATTGKDELGRPSRLCKHALYCRWMRVHGKVPPHLLRTKITKPTTYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP", "length": 705, "header": "tr|A0A9J7HA63-1|A0A9J7HA63_CRIGR Computationally mapped isoform of Double-stranded RNA-specific editase 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Adarb1 PE=4 SV=1 CANONICAL=A0A9J7H913-1" }, "locus": {} }, { "isoform_ac": "G3H8Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H913/entry#G3H8Z3-1", "sequence": { "sequence": "MDIEDEENMSSSSTDVKENRNLDNMPPKDSSTPGPVEGIPLSNGGGGSTSRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYMLLSQTGPVHAPLFVMSVEVNGQIFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKSEPPFYVGSNGDDSFSSSGDVSLSASPVPASLTQPPLPIPPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALATVFNLHLDQTPSRQPVLSEGLQLHLPQVLADAVSRLVLGKFSDLTDNFSSPHARRKVLSGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYAQLELYLNNKEDQKKSIFQKSERGGFRLKDTVQFHLYISTSPCGDARIFSPHEPVLEEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEIINATTGKDELGRPSRLCKHALYCRWMRVHGKVPPHLLRTKITKPTTYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP", "length": 701, "header": "tr|G3H8Z3-1|A0A9J7H913_CRIGR Computationally mapped isoform of Double-stranded RNA-specific editase 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Adarb1 PE=4 SV=1 CANONICAL=A0A9J7H913-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 36, "start_aa": "Thr", "end_pos": 36, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr36", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H8Z3", "url": "https://www.uniprot.org/uniprotkb/G3H8Z3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H8Z3", "url": "https://www.uniprot.org/uniprotkb/G3H8Z3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755658", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755658", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SKM0-1", "protein_name": "Adenosine deaminase RNA specific B1", "gene_name": "ADARB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGKAFRLAWRAGQGPEGRQGPEGSSPSRRHARIISAPPALQGPGGTGTRGSHDRNSLRQSRNPQKYFAMDIEDEENMSSSSTDVKENCNLDGAPPKDSSAPGPGEGAPLSNGGGGGTSRKRALDEGSNGHAKFRLKKRRRAPGPALPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFLMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRSLSTNADFTSDQADFPDALFNGFETPDRSEVPFYLGSNGDDSFSSSGDLSLAASPVPAGLAQPPLPGPPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKNFVMSVVVDGQFFEGSGRNKKLAKARAAQSALATIFNLHLDQTPSRQPIPSEGLQLHLPQVLADAVARLVLDKFGDLTDSFASPHARRKVLAGIVMTTGTDVKDAKVISISTGTKCINGEYMSDRGLALNDCHAEIIARRSLLRFLYTQLEIYLNSKDDQKRSIFEKSERGGFKLKENVQFHLYISTSPCGDARIFSPHEPILEEPADRHPNRKARGQLRTKIESGEGTIPVRSNASVQTWDGVLQGERLLTMSCSDKMARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSALEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSSLLRSKITKPNVYHESKLVAKEYQAAKACLFRAFIKAGLGAWVEKPTEQDQFSLTP", "length": 769 }, "evidence": [ { "id": "A0A9J7H913", "url": "https://omabrowser.org/oma/group/A0A9J7H913/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P51400-1", "protein_name": "Double-stranded RNA-specific editase 1", "gene_name": "Adarb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDIEDEENMSSSSIDVKENRNLDNMPPKDSSTPGPGEGIPLSNGGGGSTSRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYMLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKSEPPFYVGSNGDDSFSSSGDVSLSASPVPASLTQPPLPIPPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALATVFNLHLDQTPSRQPVLSEGLQLHLPQVLADAVSRLVLGKFSDLTDNFSSPHARRKVLSGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYAQLELYLNNKEDQKKSIFQKSERGGFRLKDTVQFHLYISTSPCGDARIFSPHEPVLEGMAPDSHQLTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGALLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDTAIEVINATTGKDELGRPSRLCKHALYCRWMRVHGKVPPHLLRTKITKPTTYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSFTP", "length": 711 }, "evidence": [ { "id": "A0A9J7H913", "url": "https://omabrowser.org/oma/group/A0A9J7H913/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P78563-1", "protein_name": "Double-stranded RNA-specific editase 1", "gene_name": "ADARB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP", "length": 741 }, "evidence": [ { "id": "A0A9J7H913", "url": "https://omabrowser.org/oma/group/A0A9J7H913/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91ZS8-1", "protein_name": "Double-stranded RNA-specific editase 1", "gene_name": "Adarb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDIEDEENMSSSSTDIKENRNLDNMPPKDSSTPGPGEGIPLSNGGGGSTSRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYMLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKSEPPFYVGSNGDDSFSSSGDVSLSASPVPASLTQPPLPIPPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALATVFNLHLDQTPSRQPVLSEGLQLHLPQVLADAVSRLVLGKFSDLTDNFSSPHARRKVLSGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYAQLELYLNNKEDQKKSIFQKSERGGFRLKDTVQFHLYISTSPCGDARIFSPHEPVLEGMTPDSHQLTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDATIEVINATTGKDELGRPSRLCKHALYCRWMRVHGKVPPHLLRTKITKPTTYHESKLAAREYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSFTP", "length": 711 }, "evidence": [ { "id": "A0A9J7H913", "url": "https://omabrowser.org/oma/group/A0A9J7H913/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NII1-1", "protein_name": "Double-stranded RNA-specific editase Adar", "gene_name": "Adar", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLNSANNNSPQHPVSAPSDINMNGYNRKLPQKRGYEMPKYSDPKKKMCKERIPQPKNTVAMLNELRHGLIYKLESQTGPVHAPLFTISVEVDGQKYLGQGRSKKVARIEAAATALRSFIQFKDGAVLSPLKPAGNLDFTSDEHLENGIENLSSSKMFEIIQTMLTEKLSNPTSLEQPTFCMSQNVSKSAITVDGQKKVPDKGPVMLLYELFNDVNFECINIDGAQNNCRFKMTVTINEKKFDGTGPSKKTAKNAAAKAALASLCNISYSPMVVPQKNVPLPIDDKSSSMELPQIHADTIGRLVLEKFMEVIKGQEAYSRRKVLAGIVMTENMNFCEAKVISVSTGTKCVSGEHMSVNGAVLNDSHAEIVSRRCLLKYLYAQLDLQCNQATAYQSIFVRNTDGQYPYKLKSGVHFHLYINTAPCGDARIFSPHENDTGVDKHPNRKARGQLRTKIESGEGTIPVKSSDGIQTWDGVLQGQRLLTMSCSDKIARWNIVGIQGSLLSSIIEPVYLHSIVLGSLLHPEHMYRAVCGRIEKSIQGLPPPYHLNKPRLALVTSAEPRNQAKAPNFGINWTIGDTELEVVNSLTGRTIGGQVSRITKQAFFVKYGFLMANLPGILVRKVTTDYGQTKANVKDYQIAKLELFSAFKREDLGSWLKKPIEQDEFGLAE", "length": 669 }, "evidence": [ { "id": "A0A9J7H913", "url": "https://omabrowser.org/oma/group/A0A9J7H913/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H913", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H913" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H913", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H913" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H913", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H913" } ], "pmid": "" }, { "name": "adenosine to inosine editing", "id": "GO:0006382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006382", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H913", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H913" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "tRNA-specific adenosine deaminase activity", "id": "GO:0008251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008251", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H913", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H913" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H913", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H913" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H913", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H913" } ], "pmid": "" }, { "name": "double-stranded RNA adenosine deaminase activity", "id": "GO:0003726", "url": 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"sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 36 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 510, "end_pos": 512 }, { "start_pos": 611, "end_pos": 613 }, { "start_pos": 615, "end_pos": 617 }, { "start_pos": 627, "end_pos": 629 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H9P0-1", "uniprot_ac": "A0A9J7H9P0", "uniprot_id": "A0A9J7H9P0_CRIGR", "mass": { "chemical_mass": 77201.0, "monoisotopic_mass": 77201.0 }, "refseq": { "ac": "XP_035305929", "name": "TBC1 domain family member 25 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305929" }, "gene_names": [ { "name": "Tbc1d25", "type": "recommended", "evidence": [ { "id": "A0A9J7H9P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0" } ] }, { "name": "Tbc1d25", "type": "synonym", "evidence": [ { "id": "XP_035305929", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305929" } ] } ], "protein_names": [ { "name": "TBC1 domain family member 25", "type": "recommended", "evidence": [ { "id": "A0A9J7H9P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0/entry#names_and_taxonomy" } ] }, { "name": "TBC1 domain family member 25 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035305929", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305929" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305929", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305929" } ] }, { "annotation": "Acts as a GTPase-activating protein specific for RAB33B. Involved in the regulation of autophagosome maturation, the process in which autophagosomes fuse with endosomes and lysosomes.", "evidence": [ { "database": "UniProtKB", "id": "G3HNE1", "url": "https://www.uniprot.org/uniprotkb/G3HNE1#function" }, { "database": "UniProtKB", "id": "ARBA00060246", "url": "https://www.uniprot.org/uniprotkb/ARBA00060246#function" }, { "database": "UniProtKB", "id": "A0A8C2MGW2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MGW2#function" }, { "database": "UniProtKB", "id": "A0A9J7H8U2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U2#function" }, { "database": "UniProtKB", "id": "A0A9J7H9M9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M9#function" }, { "database": "UniProtKB", "id": "A0A9J7H9P0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9P0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tbc1d25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0", "locus": {} } ], "crossref": [ { "id": "A0A9J7H9P0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H9P0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100765348", "url": "https://www.ncbi.nlm.nih.gov/gene/100765348", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765348", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765348", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H9P0", "url": "https://www.orthodb.org/?gene=A0A9J7H9P0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957:SF333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957:SF333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305929", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305929", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MGW2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MGW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MGW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MGW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8U2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9M9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9P0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HNE1", "url": "https://www.uniprot.org/uniprotkb/G3HNE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HNE1-1", "url": "https://www.uniprot.org/uniprotkb/G3HNE1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATTSGASDSACSAAPPLVGGAQAAAAAEEEEREVVRVRVKKCESFLSPEFRSFAVDPQITSLDVLQHILIRAFDLNGKKNFGISYLARDRLGQEAFLSLLSDWDLSTAFATASKPYLQLRVDIRPSEDMPHSVCSGPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQSILSQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRVNPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSQVGDTDFGSHRGRPVRQRHMLRPAGGGDSSFEDAVVHLATSSQGPSGGGRLLRQASLDGLQQLRDNMGPRKDFLVQLAHPATLISSKSLSEPLLNSSDPLLSSSSRPDSPSSSSPPSTQEASPSGDIAVGSPLMQDIGSPRDPGTSLPPPPPMGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRAKALFADYLQSEVWDSEEGAEATAPS", "length": 695, "header": "tr|A0A9J7H9P0-1|A0A9J7H9P0_CRIGR Isoform 1 of TBC1 domain family member 25 OS=Cricetulus griseus OX=10029 GN=Tbc1d25 PE=4 SV=1 CANONICAL=A0A9J7H9P0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MGW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0/entry#A0A8C2MGW2-1", "sequence": { "sequence": "MGPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQSILSQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRVNPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSQVGDTDFGSHRGRPVRQRHMLRPAGGGDSSFEDAVVHLATSSQGPSGGGRLLRQASLDGLQQLRDNMGPRKDFLVQLAHPATLISSKSLSEPLLNSSDPLLSSSSRPDSPSSSSPPSTQEASPSGDIAVGSPLMQDIGSPRDPGTSLPPPPPMGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRAKALFADYLQSEVWDSEEGAEATAPS", "length": 560, "header": "tr|A0A8C2MGW2-1|A0A9J7H9P0_CRIGR Computationally mapped isoform of TBC1 domain family member 25 OS=Cricetulus griseus OX=10029 GN=Tbc1d25 PE=4 SV=1 CANONICAL=A0A9J7H9P0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H8U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0/entry#A0A9J7H8U2-1", "sequence": { "sequence": "MPHSVCSGPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQSILSQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRVNPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSQVGDTDFGSHRGRPVRQRHMLRPAGGGDSSFEDAVVHLATSSQGPSGGGRLLRQASLDGLQQLRDNMGPRKDFLVQLAHPATLISSKSLSEPLLNSSDPLLSSSSRPDSPSSSSPPSTQEASPSGDIAVGSPLMQDIGSPRDPGTSLPPPPPMGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRAKALFADYLQSEVWDSEEGAEATAPS", "length": 566, "header": "tr|A0A9J7H8U2-1|A0A9J7H8U2_CRIGR Computationally mapped isoform of TBC1 domain family member 25 OS=Cricetulus griseus OX=10029 GN=Tbc1d25 PE=4 SV=1 CANONICAL=A0A9J7H9P0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0/entry#A0A9J7H9M9-1", "sequence": { "sequence": "MVPHSVCSGPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQSILSQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRVNPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSQVGDTDFGSHRGRPVRQRHMLRPAGGGDSSFEDAVVHLATSSQGPSGGGRLLRQASLDGLQQLRDNMGPRKDFLVQLAHPATLISSKSLSEPLLNSSDPLLSSSSRPDSPSSSSPPSTQEASPSGDIAVGSPLMQDIGSPRDPGTSLPPPPPMGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRAKALFADYLQSEVWDSEEGAEATAPS", "length": 567, "header": "tr|A0A9J7H9M9-1|A0A9J7H9M9_CRIGR Computationally mapped isoform of TBC1 domain family member 25 OS=Cricetulus griseus OX=10029 GN=Tbc1d25 PE=4 SV=1 CANONICAL=A0A9J7H9P0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0/entry#A0A9J7H9P0-1", "sequence": { "sequence": "MATTSGASDSACSAAPPLVGGAQAAAAAEEEEREVVRVRVKKCESFLSPEFRSFAVDPQITSLDVLQHILIRAFDLNGKKNFGISYLARDRLGQEAFLSLLSDWDLSTAFATASKPYLQLRVDIRPSEDMPHSVCSGPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQSILSQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRVNPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSQVGDTDFGSHRGRPVRQRHMLRPAGGGDSSFEDAVVHLATSSQGPSGGGRLLRQASLDGLQQLRDNMGPRKDFLVQLAHPATLISSKSLSEPLLNSSDPLLSSSSRPDSPSSSSPPSTQEASPSGDIAVGSPLMQDIGSPRDPGTSLPPPPPMGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRAKALFADYLQSEVWDSEEGAEATAPS", "length": 695, "header": "tr|A0A9J7H9P0-1|A0A9J7H9P0_CRIGR Isoform 1 of TBC1 domain family member 25 OS=Cricetulus griseus OX=10029 GN=Tbc1d25 PE=4 SV=1 CANONICAL=A0A9J7H9P0-1" }, "locus": {} }, { "isoform_ac": "G3HNE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0/entry#G3HNE1-1", "sequence": { "sequence": "MATTSGASDSACSAAPPLVGGAQAAAAAEEEEREVVRVRVKKCESFLSPEFRSFAVDPQITSLDVLQHILIRAFDLNGKKNFGISYLARDRLGQEAFLSLLSDWDLSTAFATASKPYLQLRVDIRPSEDSPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQSILSQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRVNPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSQVGDTDFGSHRGRPVRQRHMLRPAGGGDSSFEDAVVHLATSSQGPSGGGRLLRQASLDGLQQLRDNMGPRKDFLVQLAHPATLISSKSLSEPLLNSSDPLLSSSSRPDSPSSSSPPSTQEASPSGDIAVGSPLMQDIGSPRDPGTSLPPPPPMGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRAKALFADYLQSEVWDSEEGAEATAPS", "length": 688, "header": "tr|G3HNE1-1|A0A9J7H9P0_CRIGR Computationally mapped isoform of TBC1 domain family member 25 OS=Cricetulus griseus OX=10029 GN=Tbc1d25 PE=4 SV=1 CANONICAL=A0A9J7H9P0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HNE1", "url": "https://www.uniprot.org/uniprotkb/G3HNE1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HNE1", "url": "https://www.uniprot.org/uniprotkb/G3HNE1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765348", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765348", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9P0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9P0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9P0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9P0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0" } ], "pmid": "" }, { "name": "regulation of autophagosome maturation", "id": "GO:1901096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9P0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H9P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P0" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 235, "end_pos": 441, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 552, "end_pos": 554 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H770-1", "uniprot_ac": "A0A9J7H770", "uniprot_id": "A0A9J7H770_CRIGR", "mass": { "chemical_mass": 53035.0, "monoisotopic_mass": 53035.0 }, "refseq": { "ac": "XP_035304965", "name": "transcriptional enhancer factor TEF-3 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304965" }, "gene_names": [ { "name": "Tead4", "type": "recommended", "evidence": [ { "id": "A0A9J7H770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770" } ] }, { "name": "Tead4", "type": "synonym", "evidence": [ { "id": "XP_035304965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304965" } ] } ], "protein_names": [ { "name": "Transcriptional enhancer factor TEF-3", "type": "recommended", "evidence": [ { "id": "A0A9J7H770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770/entry#names_and_taxonomy" } ] }, { "name": "transcriptional enhancer factor TEF-3 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_035304965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304965" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304965", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304965" } ] }, { "annotation": "Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H770", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770#function" }, { "database": "UniProtKB", "id": "PIRNR002603", "url": "https://www.uniprot.org/uniprotkb/PIRNR002603#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H770", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tead4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770", "locus": {} } ], "crossref": [ { "id": "A0A9J7H770", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H770", "database": "AlphaFoldDB", "categories": [] }, { "id": "100763265", "url": "https://www.ncbi.nlm.nih.gov/gene/100763265", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041086", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041086", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763265", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763265", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H525", "url": "https://www.orthodb.org/?gene=A0A9J7H525", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H770", "url": "https://www.orthodb.org/?gene=A0A9J7H770", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11834", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11834", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11834:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11834:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01285", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01285", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17725", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17725", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304965", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304965", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H525", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H525", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H525-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H525-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H770", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": 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"MAAMSSAQIVSATAFHSKMALARGPGYPAISGFWQGALPGQPGTSHDVKPFSQNTYTVQPPLPLPGFESPAGPTPSPSAPPASPWQGRSVASSKLWMLEFSAFLERQQDPDTYSKHLFVHISQSSPSYSDPYLEAVDIHQIYDKFPERKGGLKELFERGPSNAFFLVKFWADLNTNIDDESNAFYGVSSQYESLENMIITCSTKVCSFGKQVVEKVETEYARYENGRYLYRIHRSPLCEYMVNFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE", "length": 305, "header": "tr|A0A9J7H525-1|A0A9J7H525_CRIGR Computationally mapped isoform of Transcriptional enhancer factor TEF-3 isoform X4 OS=Cricetulus griseus OX=10029 GN=Tead4 PE=4 SV=1 CANONICAL=A0A9J7H770-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H770-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770/entry#A0A9J7H770-1", "sequence": { "sequence": 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"MAAMSSAQIVSATAFHSKMALARGPGYPAISGFWQGALPGQPGTSHDVKPFSQNTYTVQPPLPLPGPTPSPSAPPASPWQGRSVASSKLWMLEFSAFLERQQDPDTYSKHLFVHISQSSPSYSDPYLEAVDIHQIYDKFPERKGGLKELFERGPSNAFFLVKFWADLNTNIDDESNAFYGVSSQYESLENMIITCSTKVCSFGKQVVEKVETEYARYENGRYLYRIHRSPLCEYMVNFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE", "length": 299, "header": "tr|A0A9J7H820-1|A0A9J7H820_CRIGR Computationally mapped isoform of Transcriptional enhancer factor TEF-3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tead4 PE=4 SV=1 CANONICAL=A0A9J7H770-1" }, "locus": {} }, { "isoform_ac": "G3GUJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770/entry#G3GUJ1-1", "sequence": { "sequence": "MYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLKDQAAKNKALQSMAAMSSAQIVSATAFHSKMALARGPGYPAISGFWQGALPGQPGTSHDVKPFSQNTYTVQPPLPLPGFESPAGPTPSPSAPPASPWQGRSVASSKLWMLEFSAFLERQQDPDTYSKHLFVHISQSSPSYSDPYLEAVDIHQIYDKFPERKGGLKELFERGPSNAFFLVKFWADLNTNIDDESNAFYGVSSQYESLENMIITCSTKVCSFGKQVVEKVETEYARYENGRYLYRIHRSPLCEYMVNFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE", "length": 361, "header": "tr|G3GUJ1-1|A0A9J7H770_CRIGR Computationally mapped isoform of Transcriptional enhancer factor TEF-3 OS=Cricetulus griseus OX=10029 GN=Tead4 PE=4 SV=1 CANONICAL=A0A9J7H770-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 246, "start_aa": "Thr", "end_pos": 246, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr246", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 36, "start_aa": "Thr", "end_pos": 36, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr36", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3GUJ1", "url": "https://www.uniprot.org/uniprotkb/G3GUJ1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3GUJ1", "url": "https://www.uniprot.org/uniprotkb/G3GUJ1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763265", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763265", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of stem cell population maintenance", "id": "GO:1902459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902459", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H770", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H770", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770" } ], "pmid": "" }, { "name": "hippo signaling", "id": "GO:0035329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035329", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H770", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770" } ], "pmid": "" }, { "name": "embryonic organ development", "id": "GO:0048568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048568", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H770", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H770", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H770", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H770", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H770", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H770" }, { "id": "PS51088", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51088" }, { "id": "PRU00505", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00505" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TEA", "eco_id": "ECO_0000259", "start_pos": 79, "end_pos": 155, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 36, 246 ], "snv_sites": [], "glycation_sites": [], 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H7A4-1", "uniprot_ac": "A0A9J7H7A4", "uniprot_id": "A0A9J7H7A4_CRIGR", "mass": { "chemical_mass": 95800.0, "monoisotopic_mass": 95800.0 }, "refseq": { "ac": "XP_035306268", "name": "protein Jade-1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306268" }, "gene_names": [ { "name": "Jade1", "type": "recommended", "evidence": [ { "id": "A0A9J7H7A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ] }, { "name": "Jade1", "type": "synonym", "evidence": [ { "id": "XP_035306268", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306268" } ] } ], "protein_names": [ { "name": "Protein Jade-1", "type": "recommended", "evidence": [ { "id": "A0A9J7H7A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4/entry#names_and_taxonomy" } ] }, { "name": "Jade family PHD finger protein 1", "type": "synonym", "evidence": [ { "id": "A0A9J7H7A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4/entry#names_and_taxonomy" } ] }, { "name": "PHD finger protein 17", "type": "synonym", "evidence": [ { "id": "A0A9J7H7A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4/entry#names_and_taxonomy" } ] }, { "name": "protein Jade-1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_035306268", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306268" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306268", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306268" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Jade1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4", "locus": {} } ], "crossref": [ { "id": "A0A9J7H7A4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H7A4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15671", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15671", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15679", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15679", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772857", "url": "https://www.ncbi.nlm.nih.gov/gene/100772857", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039546", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039546", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772857", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772857", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SSTCWSQ", "url": "https://omabrowser.org/oma/group/SSTCWSQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7F038", "url": "https://www.orthodb.org/?gene=A0A9J7F038", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H7A4", "url": "https://www.orthodb.org/?gene=A0A9J7H7A4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13793", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13793", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13793:SF79", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13793:SF79", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13831", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13831", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13832", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306268", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306268", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7F038", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F038", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F038-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F038-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HML1", "url": "https://www.uniprot.org/uniprotkb/G3HML1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HML1-1", "url": "https://www.uniprot.org/uniprotkb/G3HML1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASCDRGCLLSPGEIMKRGRLPSSSEDSDDNGSLSTTWSQHSRSQHGRSACSRHEDRKPSEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVASRVVSEEKSLMFIRPKKYIASSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEESLGEGAAQENGAPKCSPGSPLEPFASLEQNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFSLYTKLLEQERVSGVPSSCSSSLENMLLFNSPSVGPNAPKIEDLKWHSAFFRKQMGSTSLVHSMKKSHKRDPLQNSPGSEGKTLLKQPALCGRREGLGVPESFLSFEKTFTEARLISSAQQKNGVVTPDHGKRRDNRFHCDLIKGDLKDKSFKQSHKPLRSTDTSQRHLDNTRAATSPGIGQSAPGMRKEIVSKCNGSLVKVPTTPASPVKSWGGFRIPKKGERQQQGEALEGACHQHSDCPHLGLGRVPGKERAKNRLRSDSENDGYVPDAEMSDSESEASEKKCIHASSTISRRTDIIRRSILAS", "length": 850, "header": "tr|A0A9J7H7A4-1|A0A9J7H7A4_CRIGR Isoform 1 of Protein Jade-1 OS=Cricetulus griseus OX=10029 GN=Jade1 PE=3 SV=1 CANONICAL=A0A9J7H7A4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F038-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4/entry#A0A9J7F038-1", "sequence": { "sequence": "MKRGRLPSSSEDSDDNGSLSTTWSQHSRSQHGRSACSRHEDRKPSEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVASRVVSEEKSLMFIRPKKYIASSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEESLGEGAAQENGAPKCSPGSPLEPFASLEQNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFSLYTKLLEQERVSGVPSSCSSSLENMLLFNSPSVGPNAPKIEDLKWHSAFFRKQMGSTSLVHSMKKSHKRDPLQNSPGSEGKTLLKQPALCGRREGLGVPESFLSFEKTFTEARLISSAQQKNGVVTPDHGKRRDNRFHCDLIKGDLKDKSFKQSHKPLRSTDTSQRHLDNTRAATSPGIGQSAPGMRKEIVSKCNGSLVKVPTTPASPVKSWGGFRIPKKGERQQQGEALEGACHQHSDCPHLGLGRVPGKERAKNRLRSDSENDGYVPDAEMSDSESEASEKKCIHASSTISRRTDIIRRSILAS", "length": 835, "header": "tr|A0A9J7F038-1|A0A9J7H7A4_CRIGR Computationally mapped isoform of Protein Jade-1 OS=Cricetulus griseus OX=10029 GN=Jade1 PE=3 SV=1 CANONICAL=A0A9J7H7A4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4/entry#A0A9J7H7A4-1", "sequence": { "sequence": "MASCDRGCLLSPGEIMKRGRLPSSSEDSDDNGSLSTTWSQHSRSQHGRSACSRHEDRKPSEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVASRVVSEEKSLMFIRPKKYIASSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEESLGEGAAQENGAPKCSPGSPLEPFASLEQNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFSLYTKLLEQERVSGVPSSCSSSLENMLLFNSPSVGPNAPKIEDLKWHSAFFRKQMGSTSLVHSMKKSHKRDPLQNSPGSEGKTLLKQPALCGRREGLGVPESFLSFEKTFTEARLISSAQQKNGVVTPDHGKRRDNRFHCDLIKGDLKDKSFKQSHKPLRSTDTSQRHLDNTRAATSPGIGQSAPGMRKEIVSKCNGSLVKVPTTPASPVKSWGGFRIPKKGERQQQGEALEGACHQHSDCPHLGLGRVPGKERAKNRLRSDSENDGYVPDAEMSDSESEASEKKCIHASSTISRRTDIIRRSILAS", "length": 850, "header": "tr|A0A9J7H7A4-1|A0A9J7H7A4_CRIGR Isoform 1 of Protein Jade-1 OS=Cricetulus griseus OX=10029 GN=Jade1 PE=3 SV=1 CANONICAL=A0A9J7H7A4-1" }, "locus": {} }, { "isoform_ac": "G3HML1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4/entry#G3HML1-1", "sequence": { "sequence": "MKRGRLPSSSEDSDDNGSLSTTWSQHSRSQHGRSACSRHEDRKPSEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEEKSLMFIRPKKYIASSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEESLGEGAAQENGAPKCSPGSPLEPFASLEQNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFSLYTKLLEQERVSGVPSSCSSSLENMLLFNSPSVGPNAPKIEDLKWHSAFFRKQMGSTSLVHSMKKSHKRDPLQNSPGSEGKTLLKQPALCGRREGLGVPESFLSFEKTFTEARLISSAQQKNGVVTPDHGKRRDNRFHCDLIKGDLKDKSFKQSHKPLRSTDTSQRHLDNTRAATSPGIGQSAPGMRKEIVSKCNGSLVKVPTTPASPVKSWGGFRIPKKGERQQQGEALEGACHQHSDCPHLGLGRVPGKERAKNRLRSDSENDGYVPDAEMSDSESEASEKKCIHASSTISRRTDIIRRSILAS", "length": 834, "header": "tr|G3HML1-1|A0A9J7H7A4_CRIGR Computationally mapped isoform of Protein Jade-1 OS=Cricetulus griseus OX=10029 GN=Jade1 PE=3 SV=1 CANONICAL=A0A9J7H7A4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HML1", "url": "https://www.uniprot.org/uniprotkb/G3HML1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HML1", "url": "https://www.uniprot.org/uniprotkb/G3HML1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772857", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772857", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M9P7-1", "protein_name": "Protein Jade-1", "gene_name": "JADE1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASCDRGCLLFPGEIMKRGRLPSSSEDSDDNGSLSTTWSQNSRSQHRRSSCSRPEDRKPSEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEEKSLMFIRPKKYIVSSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKAEEGLGEGTAQENGAPECSPRDPLEPFAGLEQNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERVSGVPSSSCSSSSLENMLLFNSPSVGPDAPKIEDLKWHSAFFRKQMGTSLVHSLKKPHKRDPLQNSPGSEGKTQLKQPDLGGRREGTVGPESFLSFEKTFAEARLVSAQQKNGVVMPDHGNRRDHRFQCDLSKGDVKDRPLKQSHKPLRSTDVSQRHVDHARAAASPGAGQSAPGTRKEVVPKCNGSLIRVNYNQSAVKVPTTPASPVKNWGGFRIPKKGERQQQGEAPEAACHQHSDYSYLGLGRVPAKERAKSKLKADNENDGYVPDVEMSDSESEASEKKCIHASSSISRRTDIIRRSILAS", "length": 858 }, "evidence": [ { "id": "A0A9J7H7A4", "url": "https://omabrowser.org/oma/group/A0A9J7H7A4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0XQS9-1", "protein_name": "Protein Jade-1", "gene_name": "JADE1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLSGVQPQKQICFCFGVEVSVGLSLHPPVFSTCSEGCLLFPREIMKRRRLPSSSENSDDNGSLSTWSQHSRSHHRRSSCSRQEDRKPSEVFRTDLITAMKLHDSFQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPEPVARIVSETKAVTFTRPRKYISSSGTKPPELGYVDIRTLADSVCRYDLSDVDVAWLQLANEEFKEMGMPELDEYTMERVIEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALICSLCNEKVGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSTKRADDETFSDHLCQENGNGIQDSSLPAHIDPFHSMDQNQEEAHRVSLRKQKLQQLEDEFYTFVESLEVAKALQLPEELVGFLYQYWKLKRKANFNKPLITPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNIYAKQLEQERVSGVPSSFSTMENAVLFNSPSLGPNAPKIEDLKWHSAFFRKQMGTSLTHSLKKSHKRDGVSNSSGNSSKSMLRQPSQRGDGATPGSLLNFDKSFAETRIVSAQQKNGIVMPDHRKRRDNLPQCEVIKTELKEKTKHNHKPLRPTELSQRQSENKRAVNHSSGRSAPGTRRDIVPKCNGGLVKINSNQTVVKVPTTPTSPVKNWGGFRIPKKGERQQQGESPEETCRQNSGYPYLGVGRVSPKDRAKSKPKPDSENDGYIPDAEMSDSESEVAEKKCRQQRLSPNSTISRRTDIIRRSILAS", "length": 885 }, "evidence": [ { "id": "A0A9J7H7A4", "url": "https://omabrowser.org/oma/group/A0A9J7H7A4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZM64-1", "protein_name": "Protein Jade-1", "gene_name": "Jade1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKRGRLPSSSEDSDDNGSLSTTWSQHSRSQHGRSTCSRHEDRKPSEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEEKSLMFIRPKKYIASSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEESLGEGAAQENGATECSPQSPLEPFASLEQNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKINFNKPLITPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFSLYAKLLEQGKVSGVPSSCSSLENMLLFNSPSVGPNVPKIEDLKWHSAFFRKQMGTNLVHSLKKSHKRDALQNSSGTEGKTLLKQPGLSGRREGSGVPESLLSFEKTFAEARLISSAQQKNGVVTPDHGKRRDNRFHCDLVKGDLKDKSFKQSHKPLRSTDTSQRHLDNTRAATSPGVGQSAPGTRKEIVPKCNGSLVKVPTTPASPVKSWGGFRIPKKGERQQQGEAHDGACHQHSDCSHLGISRAPAKERSKSRLRTDSENDGYAPDGEMSDSESEASEKKCIHASSTISRRTDIIRRSILAS", "length": 832 }, "evidence": [ { "id": "A0A9J7H7A4", "url": "https://omabrowser.org/oma/group/A0A9J7H7A4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RRB5-1", "protein_name": "Protein Jade-1", "gene_name": "JADE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKRGRLPSSSEDSDDNGSLSTTWSQNSRSQHRRSSCSRHEDRKPSEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEEKSLMFIRPKKYIVSSGSEAPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEESLGEAATQENGAPECSPRDPLEPFTSLEQNQEEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERVSGVPSSSCSSSSLENILLFNSPSVGPDAPKIEDLKWHSAFFRKQMGTSLVHSLKKPHKRDPLQNSAGSEGKTLLKQPDLCSRREGMAPEGFLSFEKTFAEARLISAQQKNGVVRPDHGNRRDHRLHCDLSKGDLKDRPFKQSHKPLRSTDVSQRHLDNTRAATSPGAGQSALGTRKEMVPKCNGSLIKVNSNQTAVKVPTTPASPVKNWGGFRIPKKGERQQQGEAHEGACHQHSDYPYLGLGRVPAKERAKSKLKSDSENDGYVPDVEMSDSESEASEKKCIHASSTINRRTDIIRRSILAS", "length": 842 }, "evidence": [ { "id": "A0A9J7H7A4", "url": "https://omabrowser.org/oma/group/A0A9J7H7A4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6IE81-1", "protein_name": "Protein Jade-1", "gene_name": "JADE1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKRGRLPSSSEDSDDNGSLSTTWSQNSRSQHRRSSCSRHEDRKPSEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEEKSLMFIRPKKYIVSSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERVSGVPSSCSSSSLENMLLFNSPSVGPDAPKIEDLKWHSAFFRKQMGTSLVHSLKKPHKRDPLQNSPGSEGKTLLKQPDLCGRREGMVVPESFLGLEKTFAEARLISAQQKNGVVMPDHGKRRDNRFHCDLIKGDLKDKSFKQSHKPLRSTDVSQRHLDNTRAATSPGVGQSAPGTRKEIVPKCNGSLIKVNYNQTAVKVPTTPASPVKNWGGFRIPKKGERQQQGEAHDGACHQHSDYPYLGLGRVPAKERAKSKLKSDNENDGYVPDVEMSDSESEASEKKCIHTSSTISRRTDIIRRSILAS", "length": 842 }, "evidence": [ { "id": "A0A9J7H7A4", "url": "https://omabrowser.org/oma/group/A0A9J7H7A4/", "database": "OMA" } ], "glygen_name": "Human", 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"common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "regulation of DNA biosynthetic process", "id": "GO:2000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000278", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "regulation of cell growth", "id": "GO:0001558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001558", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "regulation of DNA replication", "id": "GO:0006275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006275", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "histone H4K12 acetyltransferase activity", "id": "GO:0043997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043997", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "histone H4K5 acetyltransferase activity", "id": "GO:0043995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043995", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "histone H4K8 acetyltransferase activity", "id": "GO:0043996", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043996", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "histone H3K14 acetyltransferase activity", "id": "GO:0036408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036408", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "histone acetyltransferase complex", "id": "GO:0000123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000123", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 739, "end_pos": 741, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H7A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7A4" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" }, { "id": "PS51805", 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H7D7-1", "uniprot_ac": "A0A9J7H7D7", "uniprot_id": "A0A9J7H7D7_CRIGR", "mass": { "chemical_mass": 18599.0, "monoisotopic_mass": 18599.0 }, "refseq": { "ac": "XP_027239882", "name": "ADP-ribose glycohydrolase OARD1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027239882" }, "gene_names": [ { "name": "Oard1", "type": "recommended", "evidence": [ { "id": "A0A9J7H7D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7" } ] }, { "name": "Oard1", "type": "synonym", "evidence": [ { "id": "XP_027239882", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027239882" } ] } ], "protein_names": [ { "name": "ADP-ribose glycohydrolase OARD1", "type": "recommended", "evidence": [ { "id": "A0A9J7H7D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7/entry#names_and_taxonomy" } ] }, { "name": "ADP-ribose glycohydrolase OARD1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027239882", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027239882" } ] }, { "name": "O-acetyl-ADP-ribose deacetylase 1", "type": "synonym", "evidence": [ { "id": "A0A9J7H7D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7/entry#names_and_taxonomy" } ] }, { "name": "Terminal ADP-ribose protein glycohydrolase 1", "type": "synonym", "evidence": [ { "id": "A0A9J7H7D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7/entry#names_and_taxonomy" } ] }, { "name": "[Protein ADP-ribosylglutamate] hydrolase OARD1", "type": "synonym", "evidence": [ { "id": "A0A9J7H7D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615227.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027239882.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027239882", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027239882" } ] }, { "annotation": "ADP-ribose glycohydrolase that hydrolyzes ADP-ribose and acts on different substrates, such as proteins ADP-ribosylated on glutamate and O-acetyl-ADP-D-ribose. Specifically acts as a glutamate mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to glutamate residues on proteins. Does not act on poly-ADP-ribosylated proteins: the poly-ADP-ribose chain of poly-ADP-ribosylated glutamate residues must by hydrolyzed into mono-ADP-ribosylated glutamate by PARG to become a substrate for OARD1. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Catalyzes the deacylation of O-acetyl-ADP-ribose, O-propionyl-ADP-ribose and O-butyryl-ADP-ribose, yielding ADP-ribose plus acetate, propionate and butyrate, respectively.", "evidence": [ { "database": "UniProtKB", "id": "G3I9V6", "url": "https://www.uniprot.org/uniprotkb/G3I9V6#function" }, { "database": "UniProtKB", "id": "ARBA00058495", "url": "https://www.uniprot.org/uniprotkb/ARBA00058495#function" }, { "database": "UniProtKB", "id": "A0A9J7H7D7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7D7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Oard1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7", "locus": {} } ], "crossref": [ { "id": "cd02901", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02901", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756378", "url": "https://www.ncbi.nlm.nih.gov/gene/100756378", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756378", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756378", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHCLKNG", "url": "https://omabrowser.org/oma/group/CHCLKNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H7D7", "url": "https://www.orthodb.org/?gene=A0A9J7H7D7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3I9V6", "url": "https://www.orthodb.org/?gene=G3I9V6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12521", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12521", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12521:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12521:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027239882", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027239882", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "68792", "url": "https://www.rhea-db.org/rhea/68792", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7F8U0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F8U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8U0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7D7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7D7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3I9V6", "url": "https://www.uniprot.org/uniprotkb/G3I9V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3I9V6-1", "url": "https://www.uniprot.org/uniprotkb/G3I9V6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKIQKEVECVTAIKFIGEVKFRVIEITYVKGDLFACSKTDSLAHCISEDCRMGAGIAVLFKKKFGGVQELLNQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLRKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWENVSVIIEEVFEATDIKITVYTL", "length": 164, "header": "tr|A0A9J7H7D7-1|A0A9J7H7D7_CRIGR Isoform 1 of ADP-ribose glycohydrolase OARD1 OS=Cricetulus griseus OX=10029 GN=Oard1 PE=4 SV=1 CANONICAL=A0A9J7H7D7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F8U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7/entry#A0A9J7F8U0-1", "sequence": { "sequence": "MGAGIAVLFKKKFGGVQELLNQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLRKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWENVSVIIEEVFEATDIKITVYTL", "length": 113, "header": "tr|A0A9J7F8U0-1|A0A9J7H7D7_CRIGR Computationally mapped isoform of ADP-ribose glycohydrolase OARD1 OS=Cricetulus griseus OX=10029 GN=Oard1 PE=4 SV=1 CANONICAL=A0A9J7H7D7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7D7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7/entry#A0A9J7H7D7-1", "sequence": { "sequence": "MKIQKEVECVTAIKFIGEVKFRVIEITYVKGDLFACSKTDSLAHCISEDCRMGAGIAVLFKKKFGGVQELLNQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLRKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWENVSVIIEEVFEATDIKITVYTL", "length": 164, "header": "tr|A0A9J7H7D7-1|A0A9J7H7D7_CRIGR Isoform 1 of ADP-ribose glycohydrolase OARD1 OS=Cricetulus griseus OX=10029 GN=Oard1 PE=4 SV=1 CANONICAL=A0A9J7H7D7-1" }, "locus": {} }, { "isoform_ac": "G3I9V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7/entry#G3I9V6-1", "sequence": { "sequence": "MASLLNEDPERSRITYVKGDLFACSKTDSLAHCISEDCRMGAGIAVLFKKKFGGVQELLNQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLRKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWENVSVIIEEVFEATDIKITVYTL", "length": 152, "header": "tr|G3I9V6-1|A0A9J7H7D7_CRIGR Computationally mapped isoform of ADP-ribose glycohydrolase OARD1 OS=Cricetulus griseus OX=10029 GN=Oard1 PE=4 SV=1 CANONICAL=A0A9J7H7D7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I9V6", "url": "https://www.uniprot.org/uniprotkb/G3I9V6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I9V6", "url": "https://www.uniprot.org/uniprotkb/G3I9V6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756378", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756378", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RVM0-1", "protein_name": "ADP-ribose glycohydrolase OARD1", "gene_name": "OARD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGSPNEDSEGSRITYVKGDLFACPKTDSLAHCISEDCRMGAGIAVLFKKKFGGVQELLSQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLQKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWEHVSAMIEEVFDATDIRITVYTL", "length": 152 }, "evidence": [ { "id": "A0A9J7H7D7", "url": "https://omabrowser.org/oma/group/A0A9J7H7D7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q1LZ74-1", "protein_name": "ADP-ribose glycohydrolase OARD1", "gene_name": "OARD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGSPNEDSEGSRITYVKGDLFACPQTDSLVHCISEDCRMGAGIAVLFKKKFGGVQELLNQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLRKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWENVSAIIEEVFEATDIRITVYTL", "length": 152 }, "evidence": [ { "id": "A0A9J7H7D7", "url": "https://omabrowser.org/oma/group/A0A9J7H7D7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8R5F3-1", "protein_name": "ADP-ribose glycohydrolase OARD1", "gene_name": "Oard1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATRLNEDPEGSRITYVKGDLFACPKTDSLAHCISEDCRMGAGIAVLFKKRFGGVQELLSQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLQKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWENVSAILEEVFESTDIKITVYTL", "length": 152 }, "evidence": [ { "id": "A0A9J7H7D7", "url": "https://omabrowser.org/oma/group/A0A9J7H7D7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y530-1", "protein_name": "ADP-ribose glycohydrolase OARD1", "gene_name": "OARD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSLNEDPEGSRITYVKGDLFACPKTDSLAHCISEDCRMGAGIAVLFKKKFGGVQELLNQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLQKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWENVSAMIEEVFEATDIKITVYTL", "length": 152 }, "evidence": [ { "id": "A0A9J7H7D7", "url": "https://omabrowser.org/oma/group/A0A9J7H7D7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7D7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7D7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7D7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7D7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "purine nucleoside binding", "id": "GO:0001883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001883", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7D7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7" } ], "pmid": "" }, { "name": "O-acetyl-ADP-ribose deacetylase activity", "id": "GO:0061463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061463", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7D7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7" } ], "pmid": "" }, { "name": "ADP-ribosylglutamate hydrolase activity", "id": "GO:0140293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140293", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7D7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7D7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7D7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7" } ], "pmid": "" }, { "name": "purine nucleoside metabolic process", "id": "GO:0042278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042278", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7D7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7" } ], "pmid": "" }, { "name": "peptidyl-glutamate ADP-deribosylation", "id": "GO:0140291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140291", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7D7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "68792", "name": "", "equation": "alpha-NAD(+) + H2O = ADP-D-ribose + nicotinamide + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8C2N2N6-1" ], "evidence": [ { "id": "68792", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/68792" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8C2N2N6", "gene_name": "Adprs", "activity": [ { "ec_number": "3.2.1.143", "activity": "[(1''->2')-ADP-alpha-D-ribose](n) + H2O = [(1''->2')-ADP-alpha-D-ribose](n-1) + ADP-D-ribose.", "evidence": [ { "id": "A0A8C2N2N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2N6" } ] }, { "ec_number": "3.2.1.143", "activity": "", "evidence": [ { "id": "A0A8C2N2N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2N6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H7D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7D7" }, { "id": "PS51154", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51154" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Macro", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 164, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H8Z7-1", "uniprot_ac": "A0A9J7H8Z7", "uniprot_id": "A0A9J7H8Z7_CRIGR", "mass": { "chemical_mass": 22762.0, "monoisotopic_mass": 22762.0 }, "refseq": { "ac": "XP_035304854", "name": "EKC/KEOPS complex subunit TPRKB isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304854" }, "gene_names": [ { "name": "Tprkb", "type": "recommended", "evidence": [ { "id": "A0A9J7H8Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7" } ] }, { "name": "Tprkb", "type": "synonym", "evidence": [ { "id": "XP_035304854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304854" } ] } ], "protein_names": [ { "name": "EKC/KEOPS complex subunit TPRKB", "type": "recommended", "evidence": [ { "id": "A0A9J7H8Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7/entry#names_and_taxonomy" } ] }, { "name": "EKC/KEOPS complex subunit TPRKB isoform X3", "type": "synonym", "evidence": [ { "id": "XP_035304854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304854" } ] }, { "name": "EKC/KEOPS complex subunit Tprkb", "type": "synonym", "evidence": [ { "id": "A0A9J7H8Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7/entry#names_and_taxonomy" } ] }, { "name": "PRPK-binding protein", "type": "synonym", "evidence": [ { "id": "A0A9J7H8Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7/entry#names_and_taxonomy" } ] }, { "name": "TP53RK-binding protein", "type": "synonym", "evidence": [ { "id": "A0A9J7H8Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304854" } ] }, { "annotation": "Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification.", "evidence": [ { "database": "UniProtKB", "id": "G3I493", "url": "https://www.uniprot.org/uniprotkb/G3I493#function" }, { "database": "UniProtKB", "id": "ARBA00053676", "url": "https://www.uniprot.org/uniprotkb/ARBA00053676#function" }, { "database": "UniProtKB", "id": "A0A9J7H8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tprkb", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7", "locus": {} } ], "crossref": [ { "id": "A0A9J7H8Z7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H8Z7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100767700", "url": "https://www.ncbi.nlm.nih.gov/gene/100767700", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767700", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767700", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IVCRMST", "url": "https://omabrowser.org/oma/group/IVCRMST/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H8Z7", "url": "https://www.orthodb.org/?gene=A0A9J7H8Z7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3I493", "url": "https://www.orthodb.org/?gene=G3I493", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15840", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15840", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15840:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15840:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304854", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3I493", "url": "https://www.uniprot.org/uniprotkb/G3I493", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3I493-1", "url": "https://www.uniprot.org/uniprotkb/G3I493-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMGDTSGSGEACFRGDDLLRRTGDWSVVLVYEMQLSQQLDLFPECRVTLLLFKDVKNAGDLKKKAMNGSINCSLINPNVIIDPFQILVAANKAVHLHKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESATSVLIVYTEEGEKQINQEHLVSQVEGQQVPLECLPEITKLSEVKKILHKRKELGPTSLWNVIWNRVTEL", "length": 203, "header": "tr|A0A9J7H8Z7-1|A0A9J7H8Z7_CRIGR Isoform 1 of EKC/KEOPS complex subunit TPRKB OS=Cricetulus griseus OX=10029 GN=Tprkb PE=3 SV=1 CANONICAL=A0A9J7H8Z7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H8Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7/entry#A0A9J7H8Z7-1", "sequence": { "sequence": "MMGDTSGSGEACFRGDDLLRRTGDWSVVLVYEMQLSQQLDLFPECRVTLLLFKDVKNAGDLKKKAMNGSINCSLINPNVIIDPFQILVAANKAVHLHKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESATSVLIVYTEEGEKQINQEHLVSQVEGQQVPLECLPEITKLSEVKKILHKRKELGPTSLWNVIWNRVTEL", "length": 203, "header": "tr|A0A9J7H8Z7-1|A0A9J7H8Z7_CRIGR Isoform 1 of EKC/KEOPS complex subunit TPRKB OS=Cricetulus griseus OX=10029 GN=Tprkb PE=3 SV=1 CANONICAL=A0A9J7H8Z7-1" }, "locus": {} }, { "isoform_ac": "G3I493-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7/entry#G3I493-1", "sequence": { "sequence": "MQLSQQLDLFPECRVTLLLFKDVKNAGDLKKKAMNGSINCSLINPNVIIDPFQILVAANKAVHLHKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESATSVLIVYTEEGEKQINQEHLVSQVEGQQVPLECLPEITKLSEVKKIYKLSSQEESIGTLLDGIICRMSTKDVL", "length": 175, "header": "tr|G3I493-1|A0A9J7H8Z7_CRIGR Computationally mapped isoform of EKC/KEOPS complex subunit TPRKB OS=Cricetulus griseus OX=10029 GN=Tprkb PE=3 SV=1 CANONICAL=A0A9J7H8Z7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I493", "url": "https://www.uniprot.org/uniprotkb/G3I493" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I493", "url": "https://www.uniprot.org/uniprotkb/G3I493" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767700", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767700", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BXT5-1", "protein_name": "EKC/KEOPS complex subunit TPRKB", "gene_name": "TPRKB", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHLTHPLELFPERSVTLLLFNRVQNAAALRKKAMEGSIEGALINPAMIVDPFQVLVAANKAVHLHKIGKMKTRTLNAEIIFNLSPNNNISDAFKKFGISDSDTAVLIVLVVDREKMVNLEDIASQVEGQQVSLDELPQLTDIAKVKKIYKITPQEEKIGTLLDGIICRISTKDV", "length": 174 }, "evidence": [ { "id": "A0A9J7H8Z7", "url": "https://omabrowser.org/oma/group/A0A9J7H8Z7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q03705-1", "protein_name": "EKC/KEOPS complex subunit CGI121", "gene_name": "CGI121", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVVSIIPQFPDIKVSLALFEQVKNAKEIRSKMSELSTSFAFIDPRLVCSGEQMYSAIYKTLIEVKYNKMRTRNLNSECVLCLSPTSNISDAFLKFGIKDDSSQLICLKFHTNTDDVDKEQLRTIMTSIVKGQEIEFNDDNLSRFYDEALIRKIYKLSDDFKPQDVNGLSRALVDAIQLRGV", "length": 181 }, "evidence": [ { "id": "A0A9J7H8Z7", "url": "https://omabrowser.org/oma/group/A0A9J7H8Z7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5PQR8-1", "protein_name": "EKC/KEOPS complex subunit Tprkb", "gene_name": "Tprkb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQLTQQLDLFPECKVTLLLFKDVKNAGDLRKKAMEGSIDGSLINANVIVDPFQILVAANKAVHLHKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESNTSVLIVYVEDGDKQVHQEHLVSQVEGQQVPLESLPEITRLSEVRKVCSTQPEEVSR", "length": 158 }, "evidence": [ { "id": "A0A9J7H8Z7", "url": "https://omabrowser.org/oma/group/A0A9J7H8Z7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8QZZ7-1", "protein_name": "EKC/KEOPS complex subunit Tprkb", "gene_name": "Tprkb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQLSQQLDLFPECRVTLLLFKDVKNAGDLRKKAMEGSIDGSLINPNVIVDPFQILVAANKAVHLHRLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISETNTSVLIVYIEDGSKQVPQEHLVSQVEGQQVPLESLPEITRLSEVKKIYKLSSQEERIGTLLDAIICRMSTKDVL", "length": 175 }, "evidence": [ { "id": "A0A9J7H8Z7", "url": "https://omabrowser.org/oma/group/A0A9J7H8Z7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3C4-1", "protein_name": "EKC/KEOPS complex subunit TPRKB", "gene_name": "TPRKB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQLTHQLDLFPECRVTLLLFKDVKNAGDLRRKAMEGTIDGSLINPTVIVDPFQILVAANKAVHLYKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISANDTSILIVYIEEGEKQINQEYLISQVEGHQVSLKNLPEIMNITEVKKIYKLSSQEESIGTLLDAIICRMSTKDVL", "length": 175 }, "evidence": [ { "id": "A0A9J7H8Z7", "url": "https://omabrowser.org/oma/group/A0A9J7H8Z7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7" } ], "pmid": "" }, { "name": "EKC/KEOPS complex", "id": "GO:0000408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000408", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "tRNA threonylcarbamoyladenosine modification", "id": "GO:0002949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002949", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 120, "end_pos": 122 }, { "start_pos": 67, "end_pos": 69 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "A0A9J7H9I0-1", "uniprot_ac": "A0A9J7H9I0", "uniprot_id": "A0A9J7H9I0_CRIGR", "mass": { "chemical_mass": 20096.0, "monoisotopic_mass": 20096.0 }, "refseq": { "ac": "XP_035307737", "name": "protein CutA isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307737" }, "gene_names": [ { "name": "Cuta", "type": "recommended", "evidence": [ { "id": "A0A9J7H9I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9I0" } ] }, { "name": "Cuta", "type": "synonym", "evidence": [ { "id": "XP_035307737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307737" } ] } ], "protein_names": [ { "name": "Protein CutA", "type": "recommended", "evidence": [ { "id": "A0A9J7H9I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9I0/entry#names_and_taxonomy" } ] }, { "name": "Brain acetylcholinesterase putative membrane anchor", "type": "synonym", "evidence": [ { "id": "A0A9J7H9I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9I0/entry#names_and_taxonomy" } ] }, { "name": "protein CutA isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035307737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307737" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307737", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307737" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9I0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9I0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cuta", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9I0", "locus": {} } ], "crossref": [ { "id": "A0A9J7H9I0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H9I0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100774038", "url": "https://www.ncbi.nlm.nih.gov/gene/100774038", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774038", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774038", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H9I0", "url": "https://www.orthodb.org/?gene=A0A9J7H9I0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23419", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23419:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23419:SF1", 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Protein CutA OS=Cricetulus griseus OX=10029 GN=Cuta PE=3 SV=1 CANONICAL=A0A9J7H9I0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H8S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9I0/entry#A0A9J7H8S3-1", "sequence": { "sequence": "MSWGRAPVVLLGGGATLLLSLLWMPALLPAASRLLLLPRAWLSMASASPPPQSSPASGSGYVPGAVVEKRLAACVNLVPQISSILCSLLSDLSSYEWKGKIEEDSEVLMMIKTQSSLVPALTEFVRSVHPYEVAEVIALPVEQGNPPYLHWVRQVTESVSDSGTTPSSA", "length": 169, "header": "tr|A0A9J7H8S3-1|A0A9J7H8S3_CRIGR Computationally mapped isoform of Protein CutA isoform X3 OS=Cricetulus griseus OX=10029 GN=Cuta PE=3 SV=1 CANONICAL=A0A9J7H9I0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9I0/entry#A0A9J7H9I0-1", "sequence": { "sequence": "MSWGRAPVVLLGGGATLLLSLLWMPALLPAASRLLLLPRAWLSMASASPPPQSSPASGSGYVPGSVSAAFVTCPNEKVAREIARAVVEKRLAACVNLVPQISSILCSLLSDLSSYEWKGKIEEDSEVLMMIKTQSSLVPALTEFVRSVHPYEVAEVIALPVEQGNPPYLHWVRQVTESVSDSGTTPSSA", "length": 189, "header": "tr|A0A9J7H9I0-1|A0A9J7H9I0_CRIGR Isoform 1 of Protein CutA OS=Cricetulus griseus OX=10029 GN=Cuta PE=3 SV=1 CANONICAL=A0A9J7H9I0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HCI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9I0/entry#A0A9J7HCI3-1", "sequence": { "sequence": "MSWGRAPVVLLGGGATLLLSLLWMPALLPAASRLLLLPRAWLSMASASPPPQSSPASGSGYVPGAVVEKRLAACVNLVPQISSIYEWKGKIEEDSEVLMMIKTQSSLVPALTEFVRSVHPYEVAEVIALPVEQGNPPYLHWVRQVTESVSDSGTTPSSA", "length": 159, "header": "tr|A0A9J7HCI3-1|A0A9J7HCI3_CRIGR Computationally mapped isoform of Protein CutA isoform X5 OS=Cricetulus griseus OX=10029 GN=Cuta PE=3 SV=1 CANONICAL=A0A9J7H9I0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KEP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9I0/entry#A0A9J7KEP1-1", "sequence": { "sequence": "MPALLPAASRLLLLPRAWLSMASASPPPQSSPASGSGYVPGSVSAAFVTCPNEKVAREIARAVVEKRLAACVNLVPQISSILCSLLSDLSSYEWKGKIEEDSEVLMMIKTQSSLVPALTEFVRSVHPYEVAEVIALPVEQGNPPYLHWVRQVTESVSDSGTTPSSA", "length": 166, "header": "tr|A0A9J7KEP1-1|A0A9J7H9I0_CRIGR Computationally mapped isoform of Protein CutA OS=Cricetulus griseus OX=10029 GN=Cuta PE=3 SV=1 CANONICAL=A0A9J7H9I0-1" }, "locus": {} }, { "isoform_ac": "G3I6V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9I0/entry#G3I6V9-1", "sequence": { "sequence": "MSWGRAPVVLLGGGATLLLSLLWMPALLPAASRLLLLPRAWLSMASASPPPQSSPASGSGYVPGSVSAAFVTCPNEKVAREIARAVVEKRLAACVNLVPQISSIYEWKGKIEEDSEVLMMIKTQSSLVPALTEFVRSVHPYEVAEVIALPVEQGNPPYLHWVRQVTESVSDSGTTPSSA", "length": 179, "header": "tr|G3I6V9-1|A0A9J7H9I0_CRIGR Computationally mapped isoform of Protein CutA OS=Cricetulus griseus OX=10029 GN=Cuta PE=3 SV=1 CANONICAL=A0A9J7H9I0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"monoisotopic_mass": 91130.0 }, "refseq": { "ac": "XP_035304717", "name": "exocyst complex component 6B isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304717" }, "gene_names": [ { "name": "Exoc6b", "type": "recommended", "evidence": [ { "id": "A0A9J7H7K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7K4" } ] }, { "name": "Exoc6b", "type": "synonym", "evidence": [ { "id": "XP_035304717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304717" } ] } ], "protein_names": [ { "name": "Exocyst complex component", "type": "recommended", "evidence": [ { "id": "A0A9J7H7K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7K4/entry#names_and_taxonomy" } ] }, { "name": "exocyst complex component 6B isoform X4", "type": "synonym", "evidence": [ { "id": "XP_035304717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304717" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304717", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304717" } ] }, { "annotation": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.", "evidence": [ { "database": "UniProtKB", "id": "G3HQH0", "url": "https://www.uniprot.org/uniprotkb/G3HQH0#function" }, { "database": "UniProtKB", "id": "PIRNR025007", "url": "https://www.uniprot.org/uniprotkb/PIRNR025007#function" }, { "database": "UniProtKB", "id": "A0A9J7H4L4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4L4#function" }, { "database": "UniProtKB", "id": "A0A9J7H7K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7K4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12702:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304717", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304717", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H4L4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7K4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HQH0", "url": "https://www.uniprot.org/uniprotkb/G3HQH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HQH0-1", "url": "https://www.uniprot.org/uniprotkb/G3HQH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKLETRIRNHDREIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQRNISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFCKVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIGETAMKQDEYMSLPAEPFLQSQFKYLKAQQQRNLDNIVLQQPRIGSKRKSKKDVYTIFDAEMESTSPKSEQDSGILDVEDEEDDEEVPGAQDLVDFSPVYRCLHIYSVLGARETFENYYRKQRRKQARLVLQPPSNMHETLDGYRKYFNQIVGFFVVEDHILHTTQGLVNRAYIDELWEMALSKTIAALRTHSSYCSDPNLVLDLKNLIVLFADTLQVYGFPVNQLFDMLLEIRDQYSETLLKKWAGVFRNILDSDNYSPIPVTSEETYKKVVGQFPFQDIELEKQPFPKKFPFSEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSNSLQNVIKRKNIGLTELVQIIINTTHLEKSCKYLEEFITNITNVLPETVHTTKLYGTTTFKDARHAAEEEIYTNLNQKIDQFLQLADYDWMTGDLDNKASDYLVDLIAFLRSTFAVFTHLPGKVAQTACMSACKHLATSLMQLLLEAEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQEDTLQLAFIDLRQLLDLFIQWDWSTYLADYGQPNCKYLRVNPVTALTLLEKMKDTSRKNNMFAQFRKNERDKQKLIDTVAKQLRGLISSHHS", "length": 782, "header": "tr|A0A9J7H7K4-1|A0A9J7H7K4_CRIGR Isoform 1 of Exocyst complex component OS=Cricetulus griseus OX=10029 GN=Exoc6b PE=3 SV=1 CANONICAL=A0A9J7H7K4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H4L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7K4/entry#A0A9J7H4L4-1", "sequence": { "sequence": "MEKLETRIRNHDREIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQRNISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFCKVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIGETAMKQGARETFENYYRKQRRKQARLVLQPPSNMHETLDGYRKYFNQIVGFFVVEDHILHTTQGLVNRAYIDELWEMALSKTIAALRTHSSYCSDPNLVLDLKNLIVLFADTLQVYGFPVNQLFDMLLEIRDQYSETLLKKWAGVFRNILDSDNYSPIPVTSEETYKKVVGQFPFQDIELEKQPFPKKFPFSEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSNSLQNVIKRKNIGLTELVQIIINTTHLEKSCKYLEEFITNITNVLPETVHTTKLYGTTTFKDARHAAEEEIYTNLNQKIDQFLQLADYDWMTGDLDNKASDYLVDLIAFLRSTFAVFTHLPGKVAQTACMSACKHLATSLMQLLLEAEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQEDTLQLAFIDLRQLLDLFIQWDWSTYLADYGQPNCKYLRVNPVTALTLLEKMKDTSRKNNMFAQFRKNERDKQKLIDTVAKQLRGLISSHHS", "length": 680, "header": "tr|A0A9J7H4L4-1|A0A9J7H7K4_CRIGR Computationally mapped isoform of Exocyst complex component OS=Cricetulus griseus OX=10029 GN=Exoc6b PE=3 SV=1 CANONICAL=A0A9J7H7K4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7K4/entry#A0A9J7H7K4-1", "sequence": { "sequence": "MEKLETRIRNHDREIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQRNISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFCKVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIGETAMKQDEYMSLPAEPFLQSQFKYLKAQQQRNLDNIVLQQPRIGSKRKSKKDVYTIFDAEMESTSPKSEQDSGILDVEDEEDDEEVPGAQDLVDFSPVYRCLHIYSVLGARETFENYYRKQRRKQARLVLQPPSNMHETLDGYRKYFNQIVGFFVVEDHILHTTQGLVNRAYIDELWEMALSKTIAALRTHSSYCSDPNLVLDLKNLIVLFADTLQVYGFPVNQLFDMLLEIRDQYSETLLKKWAGVFRNILDSDNYSPIPVTSEETYKKVVGQFPFQDIELEKQPFPKKFPFSEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSNSLQNVIKRKNIGLTELVQIIINTTHLEKSCKYLEEFITNITNVLPETVHTTKLYGTTTFKDARHAAEEEIYTNLNQKIDQFLQLADYDWMTGDLDNKASDYLVDLIAFLRSTFAVFTHLPGKVAQTACMSACKHLATSLMQLLLEAEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQEDTLQLAFIDLRQLLDLFIQWDWSTYLADYGQPNCKYLRVNPVTALTLLEKMKDTSRKNNMFAQFRKNERDKQKLIDTVAKQLRGLISSHHS", "length": 782, "header": "tr|A0A9J7H7K4-1|A0A9J7H7K4_CRIGR Isoform 1 of Exocyst complex component OS=Cricetulus griseus OX=10029 GN=Exoc6b PE=3 SV=1 CANONICAL=A0A9J7H7K4-1" }, "locus": {} }, { "isoform_ac": "G3HQH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7K4/entry#G3HQH0-1", "sequence": { "sequence": "MEKLETRIRNHDREIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQRNISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFCKVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLDNIVLQQPRIGSKRKSKKDVYTIFDAEMESTSPKSEQDSGILDVEDEEDDEEVPGAQDLVDFSPVYRCLHIYSVLGARETFENYYRKQRRKQARLVLQPPSNMHETLDGYRKYFNQIVGFFVVEDHILHTTQGLVNRAYIDELWEMALSKTIAALRTHSSYCSDPNLVLDLKNLIVLFADTLQVYGFPVNQLFDMLLEIRDQYSETLLKKWAGVFRNILDSDNYSPIPVTSEETYKKVVGQFPFQDIELEKQPFPKKFPFSEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSNSLQNVIKRKNIGLTELVQIIINTTHLEKSCKYLEEFITNITNVLPETVHTTKLYGTTTFKDARHAAEEEIYTNLNQKIDQFLQLADYDWMTGDLDNKASDYLVDLIAFLRSTFAVFTHLPGKVAQTACMSACKHLATSLMQLLLEAEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQEDTLQLAFIDLRQLLDLFIQWDWSTYLADYGQPNCKYLRVNPVTALTLLEKMKDTSRKNNMFAQFRKNERDKQKLIDTVAKQLRGLISSHHS", "length": 762, "header": "tr|G3HQH0-1|A0A9J7H7K4_CRIGR Computationally mapped isoform of Exocyst complex component OS=Cricetulus griseus OX=10029 GN=Exoc6b PE=3 SV=1 CANONICAL=A0A9J7H7K4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HQH0", "url": "https://www.uniprot.org/uniprotkb/G3HQH0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HQH0", "url": "https://www.uniprot.org/uniprotkb/G3HQH0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757038", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757038", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7K4" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7K4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7K4" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7K4" } ], "pmid": "" }, { "name": "vesicle tethering involved in exocytosis", "id": "GO:0090522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090522", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7K4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" }, { "start_pos": 550, "end_pos": 552, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H7K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7K4" }, { "id": "PF20651", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20651" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exocyst complex component EXOC6/Sec15 N-terminal", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 172, "start_aa": "Lys", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H7K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7K4" }, { "id": "PF04091", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04091" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exocyst complex subunit EXOC6/Sec15 C-terminal", "eco_id": "ECO_0000259", "start_pos": 392, "end_pos": 741, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 424, "end_pos": 426 }, { "start_pos": 533, "end_pos": 535 }, { "start_pos": 550, "end_pos": 552 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H9N1-1", "uniprot_ac": "A0A9J7H9N1", "uniprot_id": "A0A9J7H9N1_CRIGR", "mass": { "chemical_mass": 56953.0, "monoisotopic_mass": 56953.0 }, "refseq": { "ac": "XP_007644874", "name": "zinc transporter ZIP5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644874" }, "gene_names": [ { "name": "Slc39a5", "type": "recommended", "evidence": [ { "id": "A0A9J7H9N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N1" } ] }, { "name": "Slc39a5", "type": "synonym", "evidence": [ { "id": "XP_007644874", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644874" } ] } ], "protein_names": [ { "name": "Zinc transporter ZIP5 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7H9N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N1/entry#names_and_taxonomy" } ] }, { "name": "zinc transporter ZIP5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007644874", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644874" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614217.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007644874", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644874" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9N1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc39a5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N1", "locus": {} } ], "crossref": [ { "id": "100751461", "url": "https://www.ncbi.nlm.nih.gov/gene/100751461", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751461", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751461", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GANITWM", "url": "https://omabrowser.org/oma/group/GANITWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H9N1", "url": "https://www.orthodb.org/?gene=A0A9J7H9N1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12191", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12191", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12191:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12191:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007644874", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644874", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H9N1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HRP9", "url": "https://www.uniprot.org/uniprotkb/G3HRP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HRP9-1", "url": "https://www.uniprot.org/uniprotkb/G3HRP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPPVRRLLAGLCVGVVLGWVGGSVPSLGPAEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLGRVQGLRLGHHEPPTGRAAPPSGDNFTHRPQEPELSVNVWAGMPLGPSGWGELEESKAPDLPHEPGPSGLDLFHRLLLLDHSLADHLNEDCLNGSQLLVNFGLNPVAPLTPRQFALLCPALLYQIDSRVCIKTPAPAPPGDVLSALLHSALAVLLLSLPAPLSLLLLRLLGPRVLRPVLGFLGALAVGTLCGDALLHLLPHAQGGQHTRHSEQPEEDLGPGLSVLGGLFLLFVLENMLGLVRHRRLRPRCCRNKRDLGEPNPDPEDGSGMVLRPLQATSAEPEVQGQGENSQSPPAPAAPRHRGHSHEHRGGSSPSIAWMVLLGDSLHNFTDGLALGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQAGLSFRRLLLLSLVSGVLGLGGAALGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPVLLRPPEPLPVLHVFLQGLGLLLGGSLMLTIALLEEQLLPMVPDS", "length": 540, "header": "tr|A0A9J7H9N1-1|A0A9J7H9N1_CRIGR Isoform 1 of Zinc transporter ZIP5 isoform X1 OS=Cricetulus griseus OX=10029 GN=Slc39a5 PE=3 SV=1 CANONICAL=A0A9J7H9N1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H9N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N1/entry#A0A9J7H9N1-1", "sequence": { "sequence": "MGPPVRRLLAGLCVGVVLGWVGGSVPSLGPAEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLGRVQGLRLGHHEPPTGRAAPPSGDNFTHRPQEPELSVNVWAGMPLGPSGWGELEESKAPDLPHEPGPSGLDLFHRLLLLDHSLADHLNEDCLNGSQLLVNFGLNPVAPLTPRQFALLCPALLYQIDSRVCIKTPAPAPPGDVLSALLHSALAVLLLSLPAPLSLLLLRLLGPRVLRPVLGFLGALAVGTLCGDALLHLLPHAQGGQHTRHSEQPEEDLGPGLSVLGGLFLLFVLENMLGLVRHRRLRPRCCRNKRDLGEPNPDPEDGSGMVLRPLQATSAEPEVQGQGENSQSPPAPAAPRHRGHSHEHRGGSSPSIAWMVLLGDSLHNFTDGLALGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQAGLSFRRLLLLSLVSGVLGLGGAALGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPVLLRPPEPLPVLHVFLQGLGLLLGGSLMLTIALLEEQLLPMVPDS", "length": 540, "header": "tr|A0A9J7H9N1-1|A0A9J7H9N1_CRIGR Isoform 1 of Zinc transporter ZIP5 isoform X1 OS=Cricetulus griseus OX=10029 GN=Slc39a5 PE=3 SV=1 CANONICAL=A0A9J7H9N1-1" }, "locus": {} }, { "isoform_ac": "G3HRP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N1/entry#G3HRP9-1", "sequence": { "sequence": "MGPPVRRLLAGLCVGVVLGWVGGSVPSLGPAEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLGRVQGLRLGHHEPPTGRAAPPSGDNFTHRPQEPELSVNVWAGMPLGPSGWGELEESKAPDLPHEPGPSGLDLFHRLLLLDHSLADHLNEDCLNGSQLLVNFGLNPVAPLTPRQFALLCPALLYQIDSRVCIKTPAPAPPGDVLSALLHSALAVLLLSLPAPLSLLLLRLLGPRVLRPVLGFLGALAVGTLCGDALLHLLPHAQGGQHTRHSEQPEEDLGPGLSVLGGLFLLFVLENMLGLVRHRRLRPRCCRNKRDLGEPNPDPEDGSGMVLRPLQATSEPEVQGQGENSQSPPAPAAPRHRGHSHEHRGGSSPSIAWMVLLGDSLHNFTDGLALGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQAGLSFRRLLLLSLVSGVLGLGGAALGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPVLLRPPEPLPVLHVFLQGLGLLLGGSLMLTIALLEEQLLPMVPDS", "length": 539, "header": "tr|G3HRP9-1|A0A9J7H9N1_CRIGR Computationally mapped isoform of Zinc transporter ZIP5 isoform X1 OS=Cricetulus griseus OX=10029 GN=Slc39a5 PE=3 SV=1 CANONICAL=A0A9J7H9N1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HRP9", "url": "https://www.uniprot.org/uniprotkb/G3HRP9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HRP9", "url": "https://www.uniprot.org/uniprotkb/G3HRP9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751461", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751461", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZSF7-1", "protein_name": "Solute carrier family 39 member 5", "gene_name": "Slc39a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPPVHHLLAGLCVGVALGWVEGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLGRVQGLRLGHQEPPTGRAAPMSGDNFTHRLQELELSVDVWAGMPLSPSGWGDQEDSKAHDLHGSGPSGLDLFHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPVAPLTPRQFALLCPALLYQIDSRVCIKTPAPAPPGDALSALLHSGLAVLFLSLPAPFSLLLLRLLGPRLLRPVLGFLGALAVGTLCGDALLHLLPHAQGGRHTGPSEQAEEDLGPGLSVLGGLFLLFVLENALGLVRHRGLRPRCGRNKRDVEEPNPDPEDGTGMVLRPLQAASEVQGQRENSQSLPSPAPPGYQGHSHEHRGGSIAWMVLLGDCLHNLTDGLALGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQEGLSFRKLLLLSLVSGVLGLGGAALGVGLSLGPVPLTPWVFGITAGVFLYVALVDMLPALLRPPEPRPLPHVLLQGLGLLLGGSLMFTIALLEEQLLPVVPDG", "length": 533 }, "evidence": [ { "id": "A0A9J7H9N1", "url": "https://omabrowser.org/oma/group/A0A9J7H9N1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZMH5-1", "protein_name": "Zinc transporter ZIP5", "gene_name": "SLC39A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDLEESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG", "length": 540 }, "evidence": [ { "id": "A0A9J7H9N1", "url": "https://omabrowser.org/oma/group/A0A9J7H9N1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D856-1", "protein_name": "Zinc transporter ZIP5", "gene_name": "Slc39a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPPVHHLLTGLCVGVALGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLGRVQGLRLGHHEPPTGRAAPTSGDNFTHRLQEPELSVDIWAGMPLGPSGWGDQEESKAPDLHGSGPSSLDLFQRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPVAPLTPRQFALLCPALLYQIDSRVCIKTPAPAPPGDVLSALLHSGLAVLFLSLPAPLSLLLLRLLGPRLLRPVLGFLGALAVGTLCGDALLHLLPHAQGGRHTGPSEQSEEDLGPGLSVLGGLFLLFMLENTLGLVRHRGLRPRCCRNKRDLGEPNPDPEDGSGMVLRPLQAASEPEVQGQRENRQSSPSLAPPGHQGHSHEHRGGSIAWMVLLGDCLHNLTDGLALGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQEGLSFRKLLLLSLVSGALGLGGAALGVGLSLGPVPLTPWVFGTTAGVFLYVALVDMLPTLLRPPEPLPVFHVLLQGLGLLLGGSLMFTIALLEEQLVPTVPDG", "length": 535 }, "evidence": [ { "id": "A0A9J7H9N1", "url": "https://omabrowser.org/oma/group/A0A9J7H9N1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion transmembrane transporter activity", "id": "GO:0005385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005385", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9N1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N1" } ], "pmid": "" }, { "name": "monoatomic cation:bicarbonate symporter activity", "id": "GO:0140410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140410", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9N1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9N1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9N1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "BMP signaling pathway", "id": "GO:0030509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9N1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N1" } ], "pmid": "" }, { "name": "intracellular monoatomic cation homeostasis", "id": "GO:0030003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030003", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9N1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N1" } ], "pmid": "" }, { "name": "zinc ion import across plasma membrane", "id": "GO:0071578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071578", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9N1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N1" } ], "pmid": "" }, { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9N1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 395, "end_pos": 397 }, { "start_pos": 49, "end_pos": 51 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H6Y9-1", "uniprot_ac": "A0A9J7H6Y9", "uniprot_id": "A0A9J7H6Y9_CRIGR", "mass": { "chemical_mass": 33011.0, "monoisotopic_mass": 33011.0 }, "refseq": { "ac": "XP_007645482", "name": "tumor necrosis factor receptor superfamily member 27 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645482" }, "gene_names": [ { "name": "Eda2r", "type": "recommended", "evidence": [ { "id": "A0A9J7H6Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Y9" } ] }, { "name": "Eda2r", "type": "synonym", "evidence": [ { "id": "XP_007645482", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645482" } ] } ], "protein_names": [ { "name": "Tumor necrosis factor receptor superfamily member 27 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7H6Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Y9/entry#names_and_taxonomy" } ] }, { "name": "tumor necrosis factor receptor superfamily member 27 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007645482", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645482" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614284.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007645482", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645482" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Y9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Y9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Eda2r", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Y9", "locus": {} } ], "crossref": [ { "id": "cd15838", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15838", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752833", "url": "https://www.ncbi.nlm.nih.gov/gene/100752833", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001368", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001368", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022319", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022319", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047526", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047526", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752833", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752833", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FAIIYCK", "url": "https://omabrowser.org/oma/group/FAIIYCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H6Y9", "url": "https://www.orthodb.org/?gene=A0A9J7H6Y9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12120", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12120", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12120:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12120:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007645482", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645482", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H6Y9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Y9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Y9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HTK6", "url": "https://www.uniprot.org/uniprotkb/G3HTK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HTK6-1", "url": "https://www.uniprot.org/uniprotkb/G3HTK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDCQENEYQDQWGHCVTCQQCGPGQELSKDCGYGEGGDAYCTDCPPRKYKSTWGHHRCQTCITCAVINRVQKANCTNTSNAICGDCMPRFYRKTRIGGLQDQECIPCTKQTPSSEVQCTFQLSLVKVDAHTVPGKEATLVALVGSLLVVFTLAFLGLFFLYCKQIFNRHCQCVAGGSLQYEAEKAVEEDSLFPMPAGQETSPEFPVNESIFEIKPLNSVLDDDCSSTRGFPTQESFTMASCASESHSQWVHTPIECTELDLQKFSSSEPCTGAETSRENTAGSSGDRLQLHLPFQTPRL", "length": 299, "header": "tr|A0A9J7H6Y9-1|A0A9J7H6Y9_CRIGR Isoform 1 of Tumor necrosis factor receptor superfamily member 27 isoform X1 OS=Cricetulus griseus OX=10029 GN=Eda2r PE=4 SV=1 CANONICAL=A0A9J7H6Y9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H6Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Y9/entry#A0A9J7H6Y9-1", "sequence": { "sequence": "MDCQENEYQDQWGHCVTCQQCGPGQELSKDCGYGEGGDAYCTDCPPRKYKSTWGHHRCQTCITCAVINRVQKANCTNTSNAICGDCMPRFYRKTRIGGLQDQECIPCTKQTPSSEVQCTFQLSLVKVDAHTVPGKEATLVALVGSLLVVFTLAFLGLFFLYCKQIFNRHCQCVAGGSLQYEAEKAVEEDSLFPMPAGQETSPEFPVNESIFEIKPLNSVLDDDCSSTRGFPTQESFTMASCASESHSQWVHTPIECTELDLQKFSSSEPCTGAETSRENTAGSSGDRLQLHLPFQTPRL", "length": 299, "header": "tr|A0A9J7H6Y9-1|A0A9J7H6Y9_CRIGR Isoform 1 of Tumor necrosis factor receptor superfamily member 27 isoform X1 OS=Cricetulus griseus OX=10029 GN=Eda2r PE=4 SV=1 CANONICAL=A0A9J7H6Y9-1" }, "locus": {} }, { "isoform_ac": "G3HTK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Y9/entry#G3HTK6-1", "sequence": { "sequence": "MDCQENEYQDQWGHCVTCQQCGPGQELSKDCGYGEGGDAYCTDCPPRKYKSTWGHHRCQTCITCAVINRVQKANCTNTSNAICGDCMPRFYRKTRIGGLQDQECIPCTKQTPSSEVQCTFQLSLVKVDAHTVPGKEATLVALVGSLLVVFTLAFLGLFFLYCKQIFNRHCQCGGSLQYEAEKAVEEDSLFPMPAGQETSPEFPVNESIFEIKPLNSVLDDDCSSTRGFPTQESFTMASCASESHSQWVHTPIECTELDLQKFSSSEPCTGAETSRENTAGSSGDRLQLHLPFQTPRL", "length": 297, "header": "tr|G3HTK6-1|A0A9J7H6Y9_CRIGR Computationally mapped isoform of Tumor necrosis factor receptor superfamily member 27 isoform X1 OS=Cricetulus griseus OX=10029 GN=Eda2r PE=4 SV=1 CANONICAL=A0A9J7H6Y9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HTK6", "url": "https://www.uniprot.org/uniprotkb/G3HTK6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HTK6", "url": "https://www.uniprot.org/uniprotkb/G3HTK6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752833", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752833", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LND6-1", "protein_name": "Ectodysplasin A2 receptor", "gene_name": "Eda2r", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMDCQENEYRDQWGRCVTCQQCGPGQELSKDCGYGEGGDAYCIACPPRKYKSTWGHHRCQTCITCAVINRVQKANCTNTSNAICGDCLPRFYRKTRIGGLQDQECIPCTKQTPSSEVQCTFQLSLVKVDTHTLPPKEATLVALVGSLLVVFALAFLGLFFLYCKQIFNRHCQCVAGGSLQYEAEKAVQEDSLLTTPPGQETSPEFPANGSIFEIKPLNSILDDDCSSTRGFPTQESFTMASCASESHSQWVHTPIECTELDLQKFSSSVPCPGAETLRENTAEHSGDRLDLYVPFEVPSL", "length": 300 }, "evidence": [ { "id": "A0A9J7H6Y9", "url": "https://omabrowser.org/oma/group/A0A9J7H6Y9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BX35-1", "protein_name": "Tumor necrosis factor receptor superfamily member 27", "gene_name": "Eda2r", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDCQENEYRDQWGRCVTCQQCGPGQELSKDCGYGEGGDAHCIVCPPRKYKSTWGHHRCQTCITCAVINRVQKANCTNTSNAICGDCLPRFYRKTRIGGLQDQECIPCTKQTPSSEVQCTFQLSLVKVDAHTVPPREATLVALVGSLLVVFALAFLGLFFLYCKQIFNRHCQCRDSLQYEAEKTVEEDSLFPVPPGQETSPEFPANEGILEIKPLNSILDDDCSSTRGFPTQESFTMASCASESHSQWVHTPIECTELDLQKFSSSIPSTGPETLRENTAEHSGDRLELYVPFEVPSL", "length": 297 }, "evidence": [ { "id": "A0A9J7H6Y9", "url": "https://omabrowser.org/oma/group/A0A9J7H6Y9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HAV5-1", "protein_name": "Tumor necrosis factor receptor superfamily member 27", "gene_name": "EDA2R", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDCQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSCITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQTPTSEVQCAFQLSLVEADTPTVPPQEATLVALVSSLLVVFTLAFLGLFFLYCKQFFNRHCQRGGLLQFEADKTAKEESLFPVPPSKETSAESQVSENIFQTQPLNPILEDDCSSTSGFPTQESFTMASCTSESHSHWVHSPIECTELDLQKFSSSASYTGAETLGGNTVESTGDRLELNVPFEVPSP", "length": 297 }, "evidence": [ { "id": "A0A9J7H6Y9", "url": "https://omabrowser.org/oma/group/A0A9J7H6Y9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Y9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Y9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Y9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Y9" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Y9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Y9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "tumor necrosis factor receptor activity", "id": "GO:0005031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005031", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Y9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Y9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H6Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Y9" }, { "id": "PS50050", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50050" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TNFR-Cys", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 41, "start_aa": "Asp", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 207, "end_pos": 209 }, { "start_pos": 74, "end_pos": 76 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H9M2-1", "uniprot_ac": "A0A9J7H9M2", "uniprot_id": "A0A9J7H9M2_CRIGR", "mass": { "chemical_mass": 64235.0, "monoisotopic_mass": 64235.0 }, "refseq": { "ac": "XP_027290635", "name": "zinc finger protein 449 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290635" }, "gene_names": [ { "name": "Znf449", "type": "recommended", "evidence": [ { "id": "A0A9J7H9M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M2" } ] }, { "name": "Znf449", "type": "synonym", "evidence": [ { "id": "XP_027290635", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290635" } ] } ], "protein_names": [ { "name": "Zinc finger protein 449", "type": "recommended", "evidence": [ { "id": "A0A9J7H9M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M2/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 449 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027290635", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290635" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613755.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027290635.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027290635", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290635" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "G3H6L3", "url": "https://www.uniprot.org/uniprotkb/G3H6L3#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A9J7H9M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf449", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M2", "locus": {} } ], "crossref": [ { "id": "A0A9J7H9M2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H9M2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00065", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00065", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764457", "url": "https://www.ncbi.nlm.nih.gov/gene/100764457", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764457", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764457", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LDMNFPL", "url": "https://omabrowser.org/oma/group/LDMNFPL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H9M2", "url": "https://www.orthodb.org/?gene=A0A9J7H9M2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226:SF377", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226:SF377", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027290635", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290635", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H9M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H6L3", "url": "https://www.uniprot.org/uniprotkb/G3H6L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H6L3-1", "url": "https://www.uniprot.org/uniprotkb/G3H6L3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKFSLAVRDSPRLLQRGKSWNLRDRPQINCKILEEVMAVALGCAIQASLNQGSVLQEYDTDCEVFRQRFRQFQYTEAAGPHEAFNKLWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPDNRERVVSLIEDLQRELEIPEPQIDMDDMLLEELAPVGTVPMPPNLHLDAPELQVMEPVQEPPVPEAWIPQPGPQDLNYSADAECQSFLDPGYQLPKLDMNFPLDHREEPWVKELQDPKEMKQLLDSKIGFEMGIENEEDSSKEKKLETMYPFVVTLEGNALHGPILEKDYVQLENQWEPSPEDLQTDLTKLVEPQNSSLGETPESSNLEEPLNPKPPKKKSPGEKPHRCPQCGKCFARKSQLTGHQRIHSGEEPHKCPECGKRFLRSSDLYRHQRLHTGERPYECTVCKKRFTRRSHLIGHQRTHSEEETYKCLECGKSFCHGSSLKRHLKTHTGEKPHRCHNCGKSFSRLTALTLHQRTHTEERPFKCSYCGKSFRQRPSLVIHLRIHTGEKPYKCSHCSKSFRQRAGLIMHQVTHFRGLL", "length": 554, "header": "tr|A0A9J7H9M2-1|A0A9J7H9M2_CRIGR Isoform 1 of Zinc finger protein 449 OS=Cricetulus griseus OX=10029 GN=Znf449 PE=3 SV=1 CANONICAL=A0A9J7H9M2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H9M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M2/entry#A0A9J7H9M2-1", "sequence": { "sequence": "MKFSLAVRDSPRLLQRGKSWNLRDRPQINCKILEEVMAVALGCAIQASLNQGSVLQEYDTDCEVFRQRFRQFQYTEAAGPHEAFNKLWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPDNRERVVSLIEDLQRELEIPEPQIDMDDMLLEELAPVGTVPMPPNLHLDAPELQVMEPVQEPPVPEAWIPQPGPQDLNYSADAECQSFLDPGYQLPKLDMNFPLDHREEPWVKELQDPKEMKQLLDSKIGFEMGIENEEDSSKEKKLETMYPFVVTLEGNALHGPILEKDYVQLENQWEPSPEDLQTDLTKLVEPQNSSLGETPESSNLEEPLNPKPPKKKSPGEKPHRCPQCGKCFARKSQLTGHQRIHSGEEPHKCPECGKRFLRSSDLYRHQRLHTGERPYECTVCKKRFTRRSHLIGHQRTHSEEETYKCLECGKSFCHGSSLKRHLKTHTGEKPHRCHNCGKSFSRLTALTLHQRTHTEERPFKCSYCGKSFRQRPSLVIHLRIHTGEKPYKCSHCSKSFRQRAGLIMHQVTHFRGLL", "length": 554, "header": "tr|A0A9J7H9M2-1|A0A9J7H9M2_CRIGR Isoform 1 of Zinc finger protein 449 OS=Cricetulus griseus OX=10029 GN=Znf449 PE=3 SV=1 CANONICAL=A0A9J7H9M2-1" }, "locus": {} }, { "isoform_ac": "G3H6L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M2/entry#G3H6L3-1", "sequence": { "sequence": "MAVALGCAIQASLNQGSVLQEYDTDCEVFRQRFRQFQYTEAAGPHEAFNKLWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPDNRERVVSLIEDLQRELEIPEPQIDMDDMLLEELAPVGTVPMPPNLHLDAPELQVMEPVQEPPVPEAWIPQPGPQDLNYSADAECQSFLDPGYQLPKLDMNFPLDHREEPWVKELQDPKEMKQLLDSKIGFEMGIENEEDSSKEKKLETMYPFVVTLEGNALHGPILEKDYVQLENQWEPSPEDLQTDLTKLVEPQNSSLGETPESSNLEEPLNPKPPKKKSPGEKPHRCPQCGKCFARKSQLTGHQRIHSGEEPHKCPECGKRFLRSSDLYRHQRLHTGERPYECTVCKKRFTRRSHLIGHQRTHSEEETYKCLECGKSFCHGSSLKRHLKTHTGEKPHRCHNCGKSFSRLTALTLHQRTHTEERPFKCSYCGKSFRQRPSLVIHLRIHTGEKPYKCSHCSKSFRQRAGLIMHQVTHFRGLL", "length": 518, "header": "tr|G3H6L3-1|A0A9J7H9M2_CRIGR Computationally mapped isoform of Zinc finger protein 449 OS=Cricetulus griseus OX=10029 GN=Znf449 PE=3 SV=1 CANONICAL=A0A9J7H9M2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H6L3", "url": "https://www.uniprot.org/uniprotkb/G3H6L3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H6L3", "url": "https://www.uniprot.org/uniprotkb/G3H6L3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764457", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764457", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BS25-1", "protein_name": "Zinc finger protein 449", "gene_name": "ZNF449", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYKEAAGPHEAFNKLWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLIEDLQRELEIPEQQIDRQEMLLEELAPVGMAHIPPPNIHLESPPLQVMGPAPEVAVAEAWIPQAGPQELSFGAAGEGQPFLDPGYPIPKLDVSFPLEHREEAWVKELQDSKEIKQLLDSKLGFEIGIENEEDTSEKQKKLDNLYPFLVPLEGNALHGPILQKDYVQLENHWEGPSEDLQADLTKLVDRQNPPAGEKAEGSNAEEPLNPRPHKKKSPGDKPHRCSQCGKCFARKSQLTGHQRIHSGEEPHKCPECGKRFLRSSDLYRHQRLHTGERPYECTVCKKRFTRRSHLIGHQRTHSEEETYKCLECGKSFCHGSSLKRHLKTHSGEKPHRCHNCGKSFSRLTALTLHQRTHTEERPFKCNYCGKSFRQRPSLVIHLRIHTGEKPYKCSHCSKSFRQRAGLIMHQVTHFRGLL", "length": 520 }, "evidence": [ { "id": "A0A9J7H9M2", "url": "https://omabrowser.org/oma/group/A0A9J7H9M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R5T3-1", "protein_name": "Zinc finger protein 449", "gene_name": "Zfp449", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVALGRAIQASLNQGSVLQEYDTDCEVFRQRFRQFQYTEAAGPHEAFNKLWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPDNRERVVSLIEDLQRELEIPEPQIDMDDMLLEELAPVGTVPMPPNLHLEEPSLQVMAPVQEPPVPDAWIPQAGPQDLNYSTDGECQSFLDPGYQLPKLDMNFPLDHREEPWVKDLEDPKEMKQLLDSKIGFEMGIENEEDASKQKKLENLYPFVVTLEGNALHGPILQKDYVQLENEWETSPEDLQTDLTKLVDPQNPTLGETPENPDLEEPLNPKPPKKKSPGDKPHRCPQCGKCFARKSQLTGHQRIHSGEEPHKCPECGKRFLRSSDLYRHQRLHTGERPYECTVCKKRFTRRSHLLGHQRTHSEEETYKCLECGKSFCHGSSLKRHLKTHTGEKPHRCHNCGKSFSRLTALTLHQRTHTEERPFKCSYCGKSFRQRPSLVIHLRIHTGEKPYKCTHCSKSFRQRAGLIMHQVTHFRGLL", "length": 518 }, "evidence": [ { "id": "A0A9J7H9M2", "url": "https://omabrowser.org/oma/group/A0A9J7H9M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P9G9-1", "protein_name": "Zinc finger protein 449", "gene_name": "ZNF449", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYREAAGPHEAFNKLWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLIEDLQRELEIPEQQVDMHDMLLEELAPVGTAHIPPTMHLESPALQVMGPAQEAPVAEAWIPQAGPPELNYGATGECQNFLDPGYPLPKLDMNFSLENREEPWVKELQDSKEMKQLLDSKIGFEIGIENEEDTSKQKKMETMYPFIVTLEGNALQGPILQKDYVQLENQWETPPEDLQTDLAKLVDQQNPTLGETPENSNLEEPLNPKPHKKKSPGEKPHRCPQCGKCFARKSQLTGHQRIHSGEEPHKCPECGKRFLRSSDLYRHQRLHTGERPYECTVCKKRFTRRSHLIGHQRTHSEEETYKCLECGKSFCHGSSLKRHLKTHTGEKPHRCHNCGKSFSRLTALTLHQRTHTEERPFKCNYCGKSFRQRPSLVIHLRIHTGEKPYKCTHCSKSFRQRAGLIMHQVTHFRGLI", "length": 518 }, "evidence": [ { "id": "A0A9J7H9M2", "url": "https://omabrowser.org/oma/group/A0A9J7H9M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H9M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 359, "end_pos": 386, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H9M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M2" }, { "id": "PS50804", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50804" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCAN box", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 148, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 209, "end_pos": 211 }, { "start_pos": 328, "end_pos": 330 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HBC9-1", "uniprot_ac": "A0A9J7HBC9", "uniprot_id": "A0A9J7HBC9_CRIGR", "mass": { "chemical_mass": 92040.0, "monoisotopic_mass": 92040.0 }, "refseq": { "ac": "XP_035306945", "name": "neuroligin-1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306945" }, "gene_names": [ { "name": "Nlgn1", "type": "recommended", "evidence": [ { "id": "A0A9J7HBC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBC9" } ] }, { "name": "Nlgn1", "type": "synonym", "evidence": [ { "id": "XP_035306945", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306945" } ] } ], "protein_names": [ { "name": "Neuroligin-1 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7HBC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBC9/entry#names_and_taxonomy" } ] }, { "name": "neuroligin-1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035306945", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306945" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306945", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306945" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBC9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nlgn1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBC9", "locus": {} } ], "crossref": [ { "id": "A0A9J7HBC9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HBC9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100761653", "url": "https://www.ncbi.nlm.nih.gov/gene/100761653", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761653", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761653", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HBC9", "url": "https://www.orthodb.org/?gene=A0A9J7HBC9", "database": "OrthoDB", "categories": [ "Protein 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[ "Protein" ] } ], "sequence": { "sequence": "MALPRCMWPNYVWRAMMACVVHRGLGAPLALCLLGCFLQTVHVLSQKLDDVDPLVTTNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDVQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITLRPTRKNSTPVTSAFPTAKQDDPKQQPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTATNDLTHAPEEEIMSLQMKHTDLEHECESIHPHEVVLRTSCPPDYTLAMRRSPDDVPLMTPNTITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV", "length": 823, "header": "tr|A0A9J7HBC9-1|A0A9J7HBC9_CRIGR Isoform 1 of Neuroligin-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Nlgn1 PE=3 SV=1 CANONICAL=A0A9J7HBC9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QGJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBC9/entry#A0A8C2QGJ3-1", "sequence": { "sequence": "MALPRCMWPNYVWRAMMACVVHRGLGAPLALCLLGCFLQTVHVLSQKLDDVDPLVTTNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDVQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITLRPTRKNSTPVTSAFPTAKQDDPKQQPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTATNDLTHAPEEEIMSLQMKHTDLEHECESIHPHEVVLRTSCPPDYTLAMRRSPDDVPLMTPNTITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV", "length": 814, "header": "tr|A0A8C2QGJ3-1|A0A9J7HBC9_CRIGR Computationally mapped isoform of Neuroligin-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Nlgn1 PE=3 SV=1 CANONICAL=A0A9J7HBC9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HBC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBC9/entry#A0A9J7HBC9-1", "sequence": { "sequence": "MALPRCMWPNYVWRAMMACVVHRGLGAPLALCLLGCFLQTVHVLSQKLDDVDPLVTTNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDVQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITLRPTRKNSTPVTSAFPTAKQDDPKQQPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTATNDLTHAPEEEIMSLQMKHTDLEHECESIHPHEVVLRTSCPPDYTLAMRRSPDDVPLMTPNTITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV", "length": 823, "header": "tr|A0A9J7HBC9-1|A0A9J7HBC9_CRIGR Isoform 1 of Neuroligin-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Nlgn1 PE=3 SV=1 CANONICAL=A0A9J7HBC9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGJ3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGJ3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761653", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761653", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBC9" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBC9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBC9" } ], "pmid": "" }, { "name": "regulation of membrane potential", "id": "GO:0042391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBC9" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBC9" } ], "pmid": "" }, { "name": "regulation of nervous system process", "id": "GO:0031644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031644", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBC9" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBC9" } ], "pmid": "" }, { "name": "membrane assembly", "id": "GO:0071709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071709", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBC9" } ], "pmid": "" }, { "name": "positive regulation of multicellular organismal process", "id": "GO:0051240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051240", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBC9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "neurexin family protein binding", "id": "GO:0042043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042043", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 527, "end_pos": 529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 642, "end_pos": 644, "annotation": "n_glycosylation_sequon" }, { "start_pos": 805, "end_pos": 807, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HBC9", "database": "UniProtKB", "url": 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"authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H8F9-1", "uniprot_ac": "A0A9J7H8F9", "uniprot_id": "A0A9J7H8F9_CRIGR", "mass": { "chemical_mass": 274137.0, "monoisotopic_mass": 274137.0 }, "refseq": { "ac": "XP_007644101", "name": "myomegalin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644101" }, "gene_names": [ { "name": "LOC100772072", "type": "recommended", "evidence": [ { "id": "A0A9J7H8F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9" } ] }, { "name": "LOC100772072", "type": "synonym", "evidence": [ { "id": "XP_007644101", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644101" } ] } ], "protein_names": [ { "name": "Myomegalin isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7H8F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9/entry#names_and_taxonomy" } ] }, { "name": "myomegalin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007644101", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644101" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614146.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007644101", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644101" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8F9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100772072", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9", "locus": {} } ], "crossref": [ { "id": "100772072", "url": "https://www.ncbi.nlm.nih.gov/gene/100772072", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772072", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772072", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H8F9", "url": "https://www.orthodb.org/?gene=A0A9J7H8F9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7HBQ0", "url": "https://www.orthodb.org/?gene=A0A9J7HBQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46501", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46501", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46501:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46501:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26710", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26710", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007644101", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644101", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QMI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7Q9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Q9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Q9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8F9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8I2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAW5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEB3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKEICRICARELCGNQRRWIFHPASKLNLQVLLSYVLGKDVTRDGKAEFACSKCAFMLDRVYRFDTVIARIEALSLERLQKLLLEKDRLKFCIASMYRKNNDDSSEEIKAGSGTVDISSLPDMRYSALLQEDFAYSGFECWVENEEQSQESHSCHGSEGPGNRPRRCRGCAALRVADSDYEAICKVPRKVARSISYAPSSRCSTSICTEEPALSEVGPPDLASTKVPPDGESMEEGTPGSSVESLDASVQASPPQQKDEEMERSAKELLKCDYCSDEQAPQQFCNHKLELALSMIKGLEYKPLQSPRGSKLPIPVKSSPLGAKPGHIMTNGVSSSFLNRPLTPVSYPLELSDLQELWDDLYEEYLPLQFQPQPVKLLKQQKLDSDETPVSQPIMDKSVSDSHLEELQDKIQQTEASNKILQEKLNEMSCELRAAQESSQKQDVTIQSLKELLKSRESETEELYQVIEGQNETMAKLREMLRQSQLGQLHSSEGIAPTQQQVTLLDLQNALFCSQLEIQKLQRLVRQKERRLADVKRCMQFVEATAQETEQQKEASWKHNQELRKALQHLQGELHSRNQQLHTLEMEKYNEIRIREQDIQHLHQSLHLKEQLLQELQELLQYRDNPDKTLETNEVLVEKMQQQIQDRAVDLERAIDEKFSALEEKDKELQQLHRAVRERDHDLERLRSVLSANETTMQSMESLLRAKGLELEQLTATCQNLQWLKAELETKSGHWQKEQESILQQLQTSLQNKDKEVEDLRATFLSKLGPGQSEVAEELCQRLKQKEGMLQDLLSDLNKQTVEHEMEIQGLLQSMSTREQANQAAAEKMVQAFLERNTELHALRQYLGERDLIDSRALLLNQQVKVTSIGPHLGEQTDQSSVQVPSRDGNTSLTAREDASMPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQIELSALQSMMAVQEDELQVQAADLESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGQEVSGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPENSERDRTLQVELEGAQALRGRLEEVLGRSLERLSRLETMAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQLIKVALEKSLATMETQKISLQPPSSAGGDSNRCLQEELLHLRAEVHQHLEEKRKAEAELKELKAQIEEAGFSSVSHIRNTMLSLCLENAELKEQMGEAMSDGWEVEEDKEKGEVMVETVADKGGVDESSLQAEFRKVQGKLKSAHNIINILKEQLVLSNSEGSSKVMPELLVRLAREVDRMNTGLPSPGKNRHQEQENVTTRPGPRPQSLNLGAALSVDTHQLENKPQAQDSGHQPEFSLSGSTKHLRSQLAQCRQRYQDLQEKLLISEATVFAQANQLEKYRAIFSESLVKQDSKQIQVDLQDLGYETCGRSENEADRDETTSPECEEHNSPRPVMLLEGLCSDQGYLDPVLDSPPAKKPFGNNLGRQEEFQVHGSSDDSSILRKDIRDLKAQLQNANKVIQNLRSRVRSLSATSDYSSSLERPRKLRTIATLEGSSPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGLEGKLSEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHAKDTVKSFEDLLRSNDIDYYLGQSFREQLTQGGQLIERLTCKLSTKDHKSEKEEAGLEPLALRLSRELQEKEKVIEVLQAKLDTRSLSPPSSHALSDSHRSASSTSFLSDEIEACSDMDVASEYTLYDEKKPSPGHSESIHHSSHSTVLSSKPSATSASQGLKVKSSNSPIILPTPQNTPKEARQAHSGVSTAPPASTAALLSSHAEVNSPRYLNPTQPHSPTRGIMELGRIPEPGYLGSSGHWDMMRPQKGSNSGDLSSGSSLYQLNSKPTGADLLEEHLSEIRSLRQRLEESICVNDRLREQLQHRLSSTGRESGSTSHFYSQGLESVPQLYNENRALREENQSLQAQLNHASRGHSQEMDRLQEALLSSQSQLQELEKELEQQKAERQQLLEDLKEKQEEILHFREERLSLQEKDSRLQHKLAFLQQQCEEKQQLSLSLQSELQIYESLCGNPKTGLKAFSLDSCHQVPSELSYLVAEIRALRGQLEQSIQGNNCLRRQLEQQLDCGAGKANLNPSSVGQNFSASVEPASTQPLFQGSATSPPVRDVGLNSPAMVFPSSSCSVPGSDPAIITRTNELGSDDSTMMTNPPKLEGDATDGSFANKRGRHVIGHIDDYSALQQQIGEGKLLVQKILSLSRLACNIPGPEAQGTEVPGNKSIRELRSSTSALNHTLEESASLLTMFWRAALPSQHGPGLVGKAGQLIEKEILDLRAQVSQQEQLLQKTNERLKTAKQKKKNMEQYIVNHLTRTHDVLKKARTNLEVKSLRARPRTSAL", "length": 2443, "header": "tr|A0A9J7H8F9-1|A0A9J7H8F9_CRIGR Isoform 1 of Myomegalin isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100772072 PE=4 SV=1 CANONICAL=A0A9J7H8F9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QMI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9/entry#A0A8C2QMI9-1", "sequence": { "sequence": "MKEICRICARELCGNQRRWIFHPASKLNLQVLLSYVLGKDVTRDGKAEFACSKCAFMLDRVYRFDTVIARIEALSLERLQKLLLEKDRLKFCIASMYRKNNDDSSEEIKAGSGTVDISSLPDMRYSALLQEDFAYSGFECWVENEEQSQESHSCHGSEGPGNRPRRCRGCAALRVADSDYEAICKVPRKVARSISYAPSSRCSTSICTEEPALSEVGPPDLASTKVPPDGESMEEGTPGSSVESLDASVQASPPQQKDEEMERSAKELLKCDYCSDEQAPQQFCNHKLELALSMIKGLEYKPLQSPRGSKLPIPVKSSPLGAKPGHIMTNGVSSSFLNRPLTPVSYPLELSDLQELWDDLYEEYLPLQFQPQPVKLLKQQKLDSDETPVSQPIMDKSVSDSHLEELQDKIQQTEASNKILQEKLNEMSCELRAAQESSQKQDVTIQSLKELLKSRESETEELYQVIEGQNETMAKLREMLRQSQLGQLHSSEGIAPTQQQVTLLDLQNALFCSQLEIQKLQRLVRQKERRLADVKRCMQFVEATAQETEQQKEASWKHNQELRKALQHLQGELHSRNQQLHTLEMEKYNEIRIREQDIQHLHQSLHLKEQLLQELQELLQYRDNPDKTLETNEVLVEKMQQQIQDRAVDLERAIDEKFSALEEKDKELQQLHRAVRERDHDLERLRSVLSANETTMQSMESLLRAKGLELEQLTATCQNLQWLKAELETKSGHWQKEQESILQQLQTSLQNKDKEVEDLRATFLSKLGPGQSEVAEELCQRLKQKEGMLQDLLSDLNKQTVEHEMEIQGLLQSMSTREQANQAAAEKMVQAFLERNTELHALRQYLGERDLIDSRALLLNQQVKVTSIGPHLGEQTDQSSVQVPSRDGNTSLTAREDASMPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQIELSALQSMMAVQEDELQVQAADLESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGQEVSGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPENSERDRTLQVELEGAQALRGRLEEVLGRSLERLSRLETMAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQTNRLQF", "length": 1137, "header": "tr|A0A8C2QMI9-1|A0A9J7H8F9_CRIGR Computationally mapped isoform of Myomegalin isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100772072 PE=4 SV=1 CANONICAL=A0A9J7H8F9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9/entry#A0A9J7H7Q9-1", "sequence": { "sequence": "MKEICRICARELCGNQRRWIFHPASKLNLQVLLSYVLGKDVTRDGKAEFACSKCAFMLDRVYRFDTVIARIEALSLERLQKLLLEKDRLKFCIASMYRKNNDDSSEEIKAGSGTVDISSLPDMRYSALLQEDFAYSGFECWVENEEQSQESHSCHGSEGPGNRPRRCRGCAALRVADSDYEAICKVPRKVARSISYAPSSRCSTSICTEEPALSEVGPPDLASTKVPPDGESMEEGTPGSSVESLDASVQASPPQQKDEEMERSAKELLKCDYCSDEQAPQQFCNHKLELALSMIKGLEYKPLQSPRGSKLPIPVKSSPLGAKPGHIMTNGVSSSFLNRPLTPVSYPLELSDLQELWDDLYEEYLPLQFQPQPVKLLKQQKLDSDETPVSQPIMDKSVSDSHLEELQDKIQQTEASNKILQEKLNEMSCELRAAQESSQKQDVTIQSLKELLKSRESETEELYQVIEGQNETMAKLREMLRQSQLGQLHSSEGIAPTQQQVTLLDLQNALFCSQLEIQKLQRLVRQKERRLADVKRCMQFVEATAQETEQQKEASWKHNQELRKALQHLQGELHSRNQQLHTLEMEKYNEIRIREQDIQHLHQSLHLKEQLLQELQELLQYRDNPDKTLETNEVLVEKMQQQIQDRAVDLERAIDEKFSALEEKDKELQQLHRAVRERDHDLERLRSVLSANETTMQSMESLLRAKGLELEQLTATCQNLQWLKAELETKSGHWQKEQESILQQLQTSLQNKDKEVEDLRATFLSKLGPGQSEVAEELCQRLKQKEGMLQDLLSDLNKQTVEHEMEIQGLLQSMSTREQANQAAAEKMVQAFLERNTELHALRQYLGERDLIDSRALLLNQQVKVTSIGPHLGEQTDQSSVQVPSRDGNTSLTAREDASMPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQIELSALQSMMAVQEDELQVQAADLESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGQEVSGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPENSERDRTLQVELEGAQALRGRLEEVLGRSLERLSRLETMAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQLIKVALEKSLATMETQKISLQPPSSAGGDSNRCLQEELLHLRAEVHQHLEEKRKAEAELKELKAQIEEAGFSSVSHIRNTMLSLCLENAELKEQMGEAMSDGWEVEEDKEKGEVMVETVADKGGVDESSLQAEFRKVQGKLKSAHNIINILKEQLVLSNSEGSSKVMPELLVRLAREVDRMNTGLPSPGKNRHQEQENVTTRPGPRPQSLNLGAALSVDTHQLENKPQAQDSGHQPEFSLSGSTKHLRSQLAQCRQRYQDLQEKLLISEATVFAQANQLEKYRAIFSESLVKQDSKQIQVDLQDLGYETCGRSENEADRDETTSPECEEHNSPRPVMLLEGLCSDQGYLDPVLDSPPAKKPFGNNLGRQEEFQVHGSSDDSSILRKDIRDLKAQLQNANKVIQNLRSRVRSLSATSDYSSSLERPRKLRTIATLEGSSPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGLEGKLSEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHAKDTVKSFEDLLRSNDIDYYLGQSFREQLTQGGQLIERLTCKLSTKDHKSEKEEAGLEPLALRLSRELQEKEKVIEVLQAKLDTRSLSPPSSHALSDSHRSASSTSFLSDEIEACSDMDVASEYTLYDEKKPSPGHSESIHHSSHSTVLSSKPSATSASQGLKVKSSNSPIILPTPQNTPKEARQAHSGVSTAPPASTAALLSSHAEVNSPRYLNPTQPHSPTRGIMELGRIPEPGYLGSSGHWDMMRPQKGSNSGDLSSGSSLYQLNSKPTGADLLEEHLSEIRSLRQRLEESICVNDRLREQLQHRLSSTGRESGSTSHFYSQGLESVPQLYNENRALREENQSLQAQLNHASRGHSQEMDRLQEALLSSQSQLQELEKELEQQKAERQQLLEDLKEKQEEILHFREERLSLQEKDSRLQHKLAFLQQQCEEKQQLSLSLQSELQIYESLCGNPKTGLKAFSLDSCHQVPSELSYLVAEIRALRGQLEQSIQGNNCLRRQLEQQLDCGAGKANLNPSSVGQNFSASVEPASTQPLFQELGSDDSTMMTNPPKLEGDATDGSFANKRGRHVIGHIDDYSALQQQIGEGKLLVQKILSLSRLACNIPGPEAQGTEVPGNKSIRELRSSTSALNHTLEESASLLTMFWRAALPSQHGPGLVGKAGQLIEKEILDLRAQVSQQEQLLQKTNERLKTAKQKKKNMEQYIVNHLTRTHDVLKKARTNLEVKSLRARPRTSAL", "length": 2404, "header": "tr|A0A9J7H7Q9-1|A0A9J7H7Q9_CRIGR Computationally mapped isoform of Myomegalin isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100772072 PE=4 SV=1 CANONICAL=A0A9J7H8F9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H8F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9/entry#A0A9J7H8F9-1", "sequence": { "sequence": "MKEICRICARELCGNQRRWIFHPASKLNLQVLLSYVLGKDVTRDGKAEFACSKCAFMLDRVYRFDTVIARIEALSLERLQKLLLEKDRLKFCIASMYRKNNDDSSEEIKAGSGTVDISSLPDMRYSALLQEDFAYSGFECWVENEEQSQESHSCHGSEGPGNRPRRCRGCAALRVADSDYEAICKVPRKVARSISYAPSSRCSTSICTEEPALSEVGPPDLASTKVPPDGESMEEGTPGSSVESLDASVQASPPQQKDEEMERSAKELLKCDYCSDEQAPQQFCNHKLELALSMIKGLEYKPLQSPRGSKLPIPVKSSPLGAKPGHIMTNGVSSSFLNRPLTPVSYPLELSDLQELWDDLYEEYLPLQFQPQPVKLLKQQKLDSDETPVSQPIMDKSVSDSHLEELQDKIQQTEASNKILQEKLNEMSCELRAAQESSQKQDVTIQSLKELLKSRESETEELYQVIEGQNETMAKLREMLRQSQLGQLHSSEGIAPTQQQVTLLDLQNALFCSQLEIQKLQRLVRQKERRLADVKRCMQFVEATAQETEQQKEASWKHNQELRKALQHLQGELHSRNQQLHTLEMEKYNEIRIREQDIQHLHQSLHLKEQLLQELQELLQYRDNPDKTLETNEVLVEKMQQQIQDRAVDLERAIDEKFSALEEKDKELQQLHRAVRERDHDLERLRSVLSANETTMQSMESLLRAKGLELEQLTATCQNLQWLKAELETKSGHWQKEQESILQQLQTSLQNKDKEVEDLRATFLSKLGPGQSEVAEELCQRLKQKEGMLQDLLSDLNKQTVEHEMEIQGLLQSMSTREQANQAAAEKMVQAFLERNTELHALRQYLGERDLIDSRALLLNQQVKVTSIGPHLGEQTDQSSVQVPSRDGNTSLTAREDASMPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQIELSALQSMMAVQEDELQVQAADLESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGQEVSGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPENSERDRTLQVELEGAQALRGRLEEVLGRSLERLSRLETMAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQLIKVALEKSLATMETQKISLQPPSSAGGDSNRCLQEELLHLRAEVHQHLEEKRKAEAELKELKAQIEEAGFSSVSHIRNTMLSLCLENAELKEQMGEAMSDGWEVEEDKEKGEVMVETVADKGGVDESSLQAEFRKVQGKLKSAHNIINILKEQLVLSNSEGSSKVMPELLVRLAREVDRMNTGLPSPGKNRHQEQENVTTRPGPRPQSLNLGAALSVDTHQLENKPQAQDSGHQPEFSLSGSTKHLRSQLAQCRQRYQDLQEKLLISEATVFAQANQLEKYRAIFSESLVKQDSKQIQVDLQDLGYETCGRSENEADRDETTSPECEEHNSPRPVMLLEGLCSDQGYLDPVLDSPPAKKPFGNNLGRQEEFQVHGSSDDSSILRKDIRDLKAQLQNANKVIQNLRSRVRSLSATSDYSSSLERPRKLRTIATLEGSSPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGLEGKLSEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHAKDTVKSFEDLLRSNDIDYYLGQSFREQLTQGGQLIERLTCKLSTKDHKSEKEEAGLEPLALRLSRELQEKEKVIEVLQAKLDTRSLSPPSSHALSDSHRSASSTSFLSDEIEACSDMDVASEYTLYDEKKPSPGHSESIHHSSHSTVLSSKPSATSASQGLKVKSSNSPIILPTPQNTPKEARQAHSGVSTAPPASTAALLSSHAEVNSPRYLNPTQPHSPTRGIMELGRIPEPGYLGSSGHWDMMRPQKGSNSGDLSSGSSLYQLNSKPTGADLLEEHLSEIRSLRQRLEESICVNDRLREQLQHRLSSTGRESGSTSHFYSQGLESVPQLYNENRALREENQSLQAQLNHASRGHSQEMDRLQEALLSSQSQLQELEKELEQQKAERQQLLEDLKEKQEEILHFREERLSLQEKDSRLQHKLAFLQQQCEEKQQLSLSLQSELQIYESLCGNPKTGLKAFSLDSCHQVPSELSYLVAEIRALRGQLEQSIQGNNCLRRQLEQQLDCGAGKANLNPSSVGQNFSASVEPASTQPLFQGSATSPPVRDVGLNSPAMVFPSSSCSVPGSDPAIITRTNELGSDDSTMMTNPPKLEGDATDGSFANKRGRHVIGHIDDYSALQQQIGEGKLLVQKILSLSRLACNIPGPEAQGTEVPGNKSIRELRSSTSALNHTLEESASLLTMFWRAALPSQHGPGLVGKAGQLIEKEILDLRAQVSQQEQLLQKTNERLKTAKQKKKNMEQYIVNHLTRTHDVLKKARTNLEVKSLRARPRTSAL", "length": 2443, "header": "tr|A0A9J7H8F9-1|A0A9J7H8F9_CRIGR Isoform 1 of Myomegalin isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100772072 PE=4 SV=1 CANONICAL=A0A9J7H8F9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H8I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9/entry#A0A9J7H8I2-1", "sequence": { "sequence": "MKEICRICARELCGNQRRWIFHPASKLNLQVLLSYVLGKDVTRDGKAEFACSKCAFMLDRVYRFDTVIARIEALSLERLQKLLLEKDRLKFCIASMYRKNNDDSSEEIKAGSGTVDISSLPDMRYSALLQEDFAYSGFECWVENEEQSQESHSCHGSEGPGNRPRRCRGCAALRVADSDYEAICKVPRKVARSISYAPSSRCSTSICTEEPALSEVGPPDLASTKVPPDGESMEEGTPGSSVESLDASVQASPPQQKDEEMERSAKELLKCDYCSDEQAPQQFCNHKLELALSMIKGLEYKPLQSPRGSKLPIPVKSSPLGAKPGHIMTNGVSSSFLNRPLTPVSYPLELSDLQELWDDLYEEYLPLQFQPQPVKLLKQQKLDSDETPVSQPIMDKSVSDSHLEELQDKIQQTEASNKILQEKLNEMSCELRAAQESSQKQDVTIQSLKELLKSRESETEELYQVIEGQNETMAKLREMLRQSQLGQLHSSEGIAPTQQQVTLLDLQNALFCSQLEIQKLQRLVRQKERRLADVKRCMQFVEATAQETEQQKEASWKHNQELRKALQHLQGELHSRNQQLHTLEMEKYNEIRIREQDIQHLHQSLHLKEQLLQELQELLQYRDNPDKTLETNEVLVEKMQQQIQDRAVDLERAIDEKFSALEEKDKELQQLHRAVRERDHDLERLRSVLSANETTMQSMESLLRAKGLELEQLTATCQNLQWLKAELETKSGHWQKEQESILQQLQTSLQNKDKEVEDLRATFLSKLGPGQSEVAEELCQRLKQKEGMLQDLLSDLNKQTVEHEMEIQGLLQSMSTREQANQAAAEKMVQAFLERNTELHALRQYLGERDLIDSRALLLNQQVKVTSIGPHLGEQTDQSSVQVPSRDGNTSLTAREDASMPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQIELSALQSMMAVQEDELQVQAADLESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGQEVSGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPENSERDRTLQVELEGAQALRGRLEEVLGRSLERLSRLETMAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQLIKVALEKSLATMETQKISLQPPSSAGGDSNRCLQEELLHLRAEVHQHLEEKRKAEAELKELKAQIEEAGFSSVSHIRNTMLSLCLENAELKEQMGEAMSDGWEVEEDKEKGEVMVETVADKGGVDESSLQAEFRKVQGKLKSAHNIINILKEQLVLSNSEGSSKVMPELLVRLAREVDRMNTGLPSPGKNRHQEQENVTTRPGPRPQSLNLGAALSVDTHQLENKPQAQDSGHQPEFSLSGSTKHLRSQLAQCRQRYQDLQEKLLISEATVFAQANQLEKYRAIFSESLVKQDSKQIQVDLQDLGYETCGRSENEADRDETTSPECEEHNSPRPVMLLEGLCSDQGYLDPVLDSPPAKKPFGNNLGRQEEFQVHGSSDDSSILRKDIRDLKAQLQNANKVIQNLRSRVRSLSATSDYSSSLERPRKLRTIATLEGSSPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGLEGKLSEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHAKDTVKSFEDLLRSNDIDYYLGQSFREQLTQGGQLIERLTCKLSTKDHKSEKEEAGLEPLALRLSRELQEKEKVIEVLQAKLDTRSLSPPSSHALSDSHRSASSTSFLSDEIEACSDMDVASEYTLYDEKKPSPGHSATSASQGLKVKSSNSPIILPTPQNTPKEARQAHSGVSTAPPASTAALLSSHAEVNSPRYLNPTQPHSPTRGIMELGRIPEPGYLGSSGHWDMMRPQKGSNSGDLSSGSSLYQLNSKPTGADLLEEHLSEIRSLRQRLEESICVNDRLREQLQHRLSSTGRESGSTSHFYSQGLESVPQLYNENRALREENQSLQAQLNHASRGHSQEMDRLQEALLSSQSQLQELEKELEQQKAERQQLLEDLKEKQEEILHFREERLSLQEKDSRLQHKLAFLQQQCEEKQQLSLSLQSELQIYESLCGNPKTGLKAFSLDSCHQVPSELSYLVAEIRALRGQLEQSIQGNNCLRRQLEQQLDCGAGKANLNPSSVGQNFSASVEPASTQPLFQGSATSPPVRDVGLNSPAMVFPSSSCSVPGSDPAIITRTNELGSDDSTMMTNPPKLEGDATDGSFANKRGRHVIGHIDDYSALQQQIGEGKLLVQKILSLSRLACNIPGPEAQGTEVPGNKSIRELRSSTSALNHTLEESASLLTMFWRAALPSQHGPGLVGKAGQLIEKEILDLRAQVSQQEQLLQKTNERLKTAKQKKKNMEQYIVNHLTRTHDVLKKARTNLEVKSLRARPRTSAL", "length": 2426, "header": "tr|A0A9J7H8I2-1|A0A9J7H8I2_CRIGR Computationally mapped isoform of Myomegalin isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100772072 PE=4 SV=1 CANONICAL=A0A9J7H8F9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9/entry#A0A9J7HAW5-1", "sequence": { "sequence": "MEQTWARRYFGEDDGEMVPRTSSAAAFLSDTKDRGPPVQSQTWRSGERIPFGQTHSLRAFEKPPLVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDVYKRNIELKVEVESLKRELQDRKQHLDKSWADLEDLNSQNTAELHSQVEERQQETEHVYELLENKIQLLQEESRLAKNEATGTAALVEVEKGCNLELSEKLKDAVKEEEDVPRDQMKPDQYSEALAQRDRRIEELRQSLAAQEGLVDQLSQEKQQLLHLLEEPSSMEVQPQPVKLLKQQKLDSDETPVSQPIMDKSVSDSHLEELQDKIQQTEASNKILQEKLNEMSCELRAAQESSQKQDVTIQSLKELLKSRESETEELYQVIEGQNETMAKLREMLRQSQLGQLHSSEGIAPTQQQVTLLDLQNALFCSQLEIQKLQRLVRQKERRLADVKRCMQFVEATAQETEQQKEASWKHNQELRKALQHLQGELHSRNQQLHTLEMEKYNEIRIREQDIQHLHQSLHLKEQLLQELQELLQYRDNPDKTLETNEVLVEKMQQQIQDRAVDLERAIDEKFSALEEKDKELQQLHRAVRERDHDLERLRSVLSANETTMQSMESLLRAKGLELEQLTATCQNLQWLKAELETKSGHWQKEQESILQQLQTSLQNKDKEVEDLRATFLSKLGPGQSEVAEELCQRLKQKEGMLQDLLSDLNKQTVEHEMEIQGLLQSMSTREQANQAAAEKMVQAFLERNTELHALRQYLGERDLIDSRALLLNQQVKVTSIGPHLGEQTDQSSVQVPSRDGNTSLTAREDASMPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQIELSALQSMMAVQEDELQVQAADLESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGQEVSGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPENSERDRTLQVELEGAQALRGRLEEVLGRSLERLSRLETMAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQLIKVALEKSLATMETQKISLQPPSSAGGDSNRCLQEELLHLRAEVHQHLEEKRKAEAELKELKAQIEEAGFSSVSHIRNTMLSLCLENAELKEQMGEAMSDGWEVEEDKEKGEVMVETVADKGGVDESSLQAEFRKVQGKLKSAHNIINILKEQLVLSNSEGSSKVMPELLVRLAREVDRMNTGLPSPGKNRHQEQENVTTRPGPRPQSLNLGAALSVDTHQLENKPQAQDSGHQPEFSLSGSTKHLRSQLAQCRQRYQDLQEKLLISEATVFAQANQLEKYRAIFSESLVKQDSKQIQVDLQDLGYETCGRSENEADRDETTSPECEEHNSPRPVMLLEGLCSDQGYLDPVLDSPPAKKPFGNNLGRQEEFQVHGSSDDSSILRKDIRDLKAQLQNANKVIQNLRSRVRSLSATSDYSSSLERPRKLRTIATLEGSSPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGLEGKLSEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHAKDTVKSFEDLLRSNDIDYYLGQSFREQLTQGGQLIERLTCKLSTKDHKSEKEEAGLEPLALRLSRELQEKEKVIEVLQAKLDTRSLSPPSSHALSDSHRSASSTSFLSDEIEACSDMDVASEYTLYDEKKPSPGHSESIHHSSHSTVLSSKPSATSASQGLKVKSSNSPIILPTPQNTPKEARQAHSGVSTAPPASTAALLSSHAEVNSPRYLNPTQPHSPTRGIMELGRIPEPGYLGSSGHWDMMRPQKGSNSGDLSSGSSLYQLNSKPTGADLLEEHLSEIRSLRQRLEESICVNDRLREQLQHRLSSTGRESGSTSHFYSQGLESVPQLYNENRALREENQSLQAQLNHASRGHSQEMDRLQEALLSSQSQLQELEKELEQQKAERQQLLEDLKEKQEEILHFREERLSLQEKDSRLQHKLAFLQQQCEEKQQLSLSLQSELQIYESLCGNPKTGLKAFSLDSCHQVPSELSYLVAEIRALRGQLEQSIQGNNCLRRQLEQQLDCGAGKANLNPSSVGQNFSASVEPASTQPLFQGSATSPPVRDVGLNSPAMVFPSSSCSVPGSDPAIITRTNELGSDDSTMMTNPPKLEGDATDGSFANKRGRHVIGHIDDYSALQQQIGEGKLLVQKILSLSRLACNIPGPEAQGTEVPGNKSIRELRSSTSALNHTLEESASLLTMFWRAALPSQHGPGLVGKAGQLIEKEILDLRAQVSQQEQLLQKTNERLKTAKQKKKNMEQYIVNHLTRTHDVLKKARTNLEHSSYKIASVQPYSCPSKGEILKGPATHLSLVTLAFQEPHKKRSQKPLKQQEGWACPSLVQLPIC", "length": 2402, "header": "tr|A0A9J7HAW5-1|A0A9J7HAW5_CRIGR Computationally mapped isoform of Myomegalin isoform X8 OS=Cricetulus griseus OX=10029 GN=LOC100772072 PE=4 SV=1 CANONICAL=A0A9J7H8F9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HBJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9/entry#A0A9J7HBJ0-1", "sequence": { "sequence": "MEQTWARRYFGEDDGEMVPRTSSAAAFLSDTKDRGPPVQSQTWRSGERIPFGQTHSLRAFEKPPLVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDVYKRNIELKVEVESLKRELQDRKQHLDKSWADLEDLNSQNTAELHSQVEERQQETEHVYELLENKIQLLQEESRLAKNEATGTAALVEVEKGCNLELSEKLKDAVKEEEDVPRDQMKPDQYSEALAQRDRRIEELRQSLAAQEGLVDQLSQEKQQLLHLLEEPSSMEVQPQPVKLLKQQKLDSDETPVSQPIMDKSVSDSHLEELQDKIQQTEASNKILQEKLNEMSCELRAAQESSQKQDVTIQSLKELLKSRESETEELYQVIEGQNETMAKLREMLRQSQLGQLHSSEGIAPTQQQVTLLDLQNALFCSQLEIQKLQRLVRQKERRLADVKRCMQFVEATAQETEQQKEASWKHNQELRKALQHLQGELHSRNQQLHTLEMEKYNEIRIREQDIQHLHQSLHLKEQLLQELQELLQYRDNPDKTLETNEVLVEKMQQQIQDRAVDLERAIDEKFSALEEKDKELQQLHRAVRERDHDLERLRSVLSANETTMQSMESLLRAKGLELEQLTATCQNLQWLKAELETKSGHWQKEQESILQQLQTSLQNKDKEVEDLRATFLSKLGPGQSEVAEELCQRLKQKEGMLQDLLSDLNKQTVEHEMEIQGLLQSMSTREQANQAAAEKMVQAFLERNTELHALRQYLGERDLIDSRALLLNQQVKVTSIGPHLGEQTDQSSVQVPSRDGNTSLTAREDASMPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQIELSALQSMMAVQEDELQVQAADLESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGQEVSGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPENSERDRTLQVELEGAQALRGRLEEVLGRSLERLSRLETMAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQLIKVALEKSLATMETQKISLQPPSSAGGDSNRCLQEELLHLRAEVHQHLEEKRKAEAELKELKAQIEEAGFSSVSHIRNTMLSLCLENAELKEQMGEAMSDGWEVEEDKEKGEVMVETVADKGGVDESSLQAEFRKVQGKLKSAHNIINILKEQLVLSNSEGSSKVMPELLVRLAREVDRMNTGLPSPGKNRHQEQENVTTRPGPRPQSLNLGAALSVDTHQLENKPQAQDSGHQPEFSLSGSTKHLRSQLAQCRQRYQDLQEKLLISEATVFAQANQLEKYRAIFSESLVKQDSKQIQVDLQDLGYETCGRSENEADRDETTSPECEEHNSPRPVMLLEGLCSDQGYLDPVLDSPPAKKPFGNNLGRQEEFQVHGSSDDSSILRKDIRDLKAQLQNANKVIQNLRSRVRSLSATSDYSSSLERPRKLRTIATLEGSSPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGLEGKLSEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHAKDTVKSFEDLLRSNDIDYYLGQSFREQLTQGGQLIERLTCKLSTKDHKSEKEEAGLEPLALRLSRELQEKEKVIEVLQAKLDTRSLSPPSSHALSDSHRSASSTSFLSDEIEACSDMDVASEYTLYDEKKPSPGHSATSASQGLKVKSSNSPIILPTPQNTPKEARQAHSGVSTAPPASTAALLSSHAEVNSPRYLNPTQPHSPTRGIMELGRIPEPGYLGSSGHWDMMRPQKGSNSGDLSSGSSLYQLNSKPTGADLLEEHLSEIRSLRQRLEESICVNDRLREQLQHRLSSTGRESGSTSHFYSQGLESVPQLYNENRALREENQSLQAQLNHASRGHSQEMDRLQEALLSSQSQLQELEKELEQQKAERQQLLEDLKEKQEEILHFREERLSLQEKDSRLQHKLAFLQQQCEEKQQLSLSLQSELQIYESLCGNPKTGLKAFSLDSCHQVPSELSYLVAEIRALRGQLEQSIQGNNCLRRQLEQQLDCGAGKANLNPSSVGQNFSASVEPASTQPLFQGSATSPPVRDVGLNSPAMVFPSSSCSVPGSDPAIITRTNELGSDDSTMMTNPPKLEGDATDGSFANKRGRHVIGHIDDYSALQQQIGEGKLLVQKILSLSRLACNIPGPEAQGTEVPGNKSIRELRSSTSALNHTLEESASLLTMFWRAALPSQHGPGLVGKAGQLIEKEILDLRAQVSQQEQLLQKTNERLKTAKQKKKNMEQYIVNHLTRTHDVLKKARTNLEVKSLRARPRTSAL", "length": 2334, "header": "tr|A0A9J7HBJ0-1|A0A9J7HBJ0_CRIGR Computationally mapped isoform of Myomegalin isoform X4 OS=Cricetulus griseus OX=10029 GN=LOC100772072 PE=4 SV=1 CANONICAL=A0A9J7H8F9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HBQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9/entry#A0A9J7HBQ0-1", "sequence": { "sequence": "MEQTWARRYFGEDDGEMVPRTSSAAAFLSDTKDRGPPVQSQTWRSGERIPFGQTHSLRAFEKPPLVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDVYKRNIELKVEVESLKRELQDRKQHLDKSWADLEDLNSQNTAELHSQVEERQQETEHVYELLENKIQLLQEESRLAKNEATGTAALVEVEKGCNLELSEKLKDAVKEEEDVPRDQMKPDQYSEALAQRDRRIEELRQSLAAQEGLVDQLSQEKQQLLHLLEEPSSMEVQPQPVKLLKQQKLDSDETPVSQPIMDKSVSDSHLEELQDKIQQTEASNKILQEKLNEMSCELRAAQESSQKQDVTIQSLKELLKSRESETEELYQVIEGQNETMAKLREMLRQSQLGQLHSSEGIAPTQQQVTLLDLQNALFCSQLEIQKLQRLVRQKERRLADVKRCMQFVEATAQETEQQKEASWKHNQELRKALQHLQGELHSRNQQLHTLEMEKYNEIRIREQDIQHLHQSLHLKEQLLQELQELLQYRDNPDKTLETNEVLVEKMQQQIQDRAVDLERAIDEKFSALEEKDKELQQLHRAVRERDHDLERLRSVLSANETTMQSMESLLRAKGLELEQLTATCQNLQWLKAELETKSGHWQKEQESILQQLQTSLQNKDKEVEDLRATFLSKLGPGQSEVAEELCQRLKQKEGMLQDLLSDLNKQTVEHEMEIQGLLQSMSTREQANQAAAEKMVQAFLERNTELHALRQYLGERDLIDSRALLLNQQVKVTSIGPHLGEQTDQSSVQVPSRDGNTSLTAREDASMPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQIELSALQSMMAVQEDELQVQAADLESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGQEVSGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPENSERDRTLQVELEGAQALRGRLEEVLGRSLERLSRLETMAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQLIKVALEKSLATMETQKISLQPPSSAGGDSNRCLQEELLHLRAEVHQHLEEKRKAEAELKELKAQIEEAGFSSVSHIRNTMLSLCLENAELKEQMGEAMSDGWEVEEDKEKGEVMVETVADKGGVDESSLQAEFRKVQGKLKSAHNIINILKEQLVLSNSEGSSKVMPELLVRLAREVDRMNTGLPSPGKNRHQEQENVTTRPGPRPQSLNLGAALSVDTHQLENKPQAQDSGHQPEFSLSGSTKHLRSQLAQCRQRYQDLQEKLLISEATVFAQANQLEKYRAIFSESLVKQDSKQIQVDLQDLGYETCGRSENEADRDETTSPECEEHNSPRPVMLLEGLCSDQGYLDPVLDSPPAKKPFGNNLGRQEEFQVHGSSDDSSILRKDIRDLKAQLQNANKVIQNLRSRVRSLSATSDYSSSLERPRKLRTIATLEGSSPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGLEGKLSEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHAKDTVKSFEDLLRSNDIDYYLGQSFREQLTQGGQLIERLTCKLSTKDHKSEKEEAGLEPLALRLSRELQEKEKVIEVLQAKLDTRSLSPPSSHALSDSHRSASSTSFLSDEIEACSDMDVASEYTLYDEKKPSPGHSESIHHSSHSTVLSSKPSATSASQGLKVKSSNSPIILPTPQNTPKEARQAHSGVSTAPPASTAALLSSHAEVNSPRYLNPTQPHSPTRGIMELGRIPEPGYLGSSGHWDMMRPQKGSNSGDLSSGSSLYQLNSKPTGADLLEEHLSEIRSLRQRLEESICVNDRLREQLQHRLSSTGRESGSTSHFYSQGLESVPQLYNENRALREENQSLQAQLNHASRGHSQEMDRLQEALLSSQSQLQELEKELEQQKAERQQLLEDLKEKQEEILHFREERLSLQEKDSRLQHKLAFLQQQCEEKQQLSLSLQSELQIYESLCGNPKTGLKAFSLDSCHQVPSELSYLVAEIRALRGQLEQSIQGNNCLRRQLEQQLDCGAGKANLNPSSVGQNFSASVEPASTQPLFQGSATSPPVRDVGLNSPAMVFPSSSCSVPGSDPAIITRTNELGSDDSTMMTNPPKLEGDATDGSFANKRGRHVIGHIDDYSALQQQIGEGKLLVQKILSLSRLACNIPGPEAQGTEVPGNKSIRELRSSTSALNHTLEESASLLTMFWRAALPSQHGPGLVGKAGQLIEKEILDLRAQVSQQEQLLQKTNERLKTAKQKKKNMEQYIVNHLTRTHDVLKKARTNLEVKSLRARPRTSAL", "length": 2351, "header": "tr|A0A9J7HBQ0-1|A0A9J7HBQ0_CRIGR Computationally mapped isoform of Myomegalin isoform X6 OS=Cricetulus griseus OX=10029 GN=LOC100772072 PE=4 SV=1 CANONICAL=A0A9J7H8F9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KEB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9/entry#A0A9J7KEB3-1", "sequence": { "sequence": 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"length": 2322, "header": "tr|A0A9J7KEB3-1|A0A9J7H8F9_CRIGR Computationally mapped isoform of Myomegalin isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100772072 PE=4 SV=1 CANONICAL=A0A9J7H8F9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1103, "start_aa": "Thr", "end_pos": 1103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1103", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1841, "start_aa": "Thr", "end_pos": 1841, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1841", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 497, "start_aa": "Thr", "end_pos": 497, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr497", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMI9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMI9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772072", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772072", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8F9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8F9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8F9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "centrosome cycle", "id": "GO:0007098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007098", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8F9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9" } ], "pmid": "" }, { "name": "positive regulation of microtubule nucleation", "id": "GO:0090063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090063", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8F9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F9" } ], "pmid": "" }, { "name": 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"XP_035305528", "name": "matrilin-2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305528" }, "gene_names": [ { "name": "Matn2", "type": "recommended", "evidence": [ { "id": "A0A9J7H875", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H875" } ] }, { "name": "Matn2", "type": "synonym", "evidence": [ { "id": "XP_035305528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305528" } ] } ], "protein_names": [ { "name": "Matrilin-2", "type": "recommended", "evidence": [ { "id": "A0A9J7H875", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H875/entry#names_and_taxonomy" } ] }, { "name": "matrilin-2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305528" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305528" } ] }, { "annotation": "Involved in matrix assembly.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QNR7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNR7#function" }, { "database": "UniProtKB", "id": "ARBA00058687", "url": "https://www.uniprot.org/uniprotkb/ARBA00058687#function" }, { "database": "UniProtKB", "id": "A0A9J7H875", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H875#function" }, { "database": "UniProtKB", "id": "A0A9J7HA78", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA78#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H875", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H875" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Matn2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H875", "locus": {} } ], "crossref": [ { "id": "A0A9J7H875", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H875", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01475", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01475", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754409", "url": "https://www.ncbi.nlm.nih.gov/gene/100754409", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754409", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754409", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H875", "url": "https://www.orthodb.org/?gene=A0A9J7H875", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47333:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47333:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10393", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10393", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305528", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QNR7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QNR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H875", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H875", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H875-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H875-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA78", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA78-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKMLVACLLMLGQFLLLPAGARDRPQARFPSRGRHVRTHPQTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFILDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKRKSDVERAVKRMRHLSTGTMTGLAIQYALNIAFSEVEGARPLRENVPRVIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDLNTLKAIGSEPHKDHVFLVANFSQIESLTSVFQNKLCAVHMCSVLEHDCAHFCINTPGSYTCRCKQGYILNSDQKTCRIQDLCATEDHGCEQLCVNVPGSFVCQCYSGYTLGQDGKRCAAVDFCASENHGCEHACVNAEGSYLCQCREGFALNPDKKTCTKIDHCASSNHGCQHECVNALTSAFCRCLKGFMLNPDRKTCRRINYCALNKPGCEHECVNTEEGHYCRCRQGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEESFVCQCSEGFLINDDLKTCSRVDYCLLSDHGCEYSCVNTDRSFACQCPEGHALRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCRCFEGYILRDDGKTCRRKDVCQAVDHGCEHLCVNSGESYICKCLEGFGLAEDGKRCRRKDVCKSTHHGCEHICVNNGDFYTCRCSEGFVLAEDGRRCKRCTEGPIDLVFVIDGSKSLGEDNFEIVKHFVTGIIDSLAVSPKAARVGLLQYSTQVHTEFSLRDFSSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQVEGARPLSTRVPRVAIVFTDGRAQDDVSEWASKAKATGITMYAVGVGKAIEEELQEIASEPTGKHLFYAEDFSTMGEISGKLKQGICEALEDSDGRQDSPAEEPSKQVHQPTESEPVTINIRDLLSCSNFAVQHRYLFEEDKLSRSTQKLFHSTKFSGSPLEESQDQCKCENLLTFQNLANEEVRKLTQRLEEMTQRMEALENRLRYR", "length": 955, "header": "tr|A0A9J7H875-1|A0A9J7H875_CRIGR Isoform 1 of Matrilin-2 OS=Cricetulus griseus OX=10029 GN=Matn2 PE=4 SV=1 CANONICAL=A0A9J7H875-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QNR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H875/entry#A0A8C2QNR7-1", "sequence": { "sequence": "MEKMLVACLLMLGQFLLLPAGARDRPQARFPSRGRHVRTHPQTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFILDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKRKSDVERAVKRMRHLSTGTMTGLAIQYALNIAFSEVEGARPLRENVPRVIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDLNTLKAIGSEPHKDHVFLVANFSQIESLTSVFQNKLCAVHMCSVLEHDCAHFCINTPGSYTCRCKQGYILNSDQKTCRIQDLCATEDHGCEQLCVNVPGSFVCQCYSGYTLGQDGKRCAAVDFCASENHGCEHACVNAEGSYLCQCREGFALNPDKKTCTKIDHCASSNHGCQHECVNALTSAFCRCLKGFMLNPDRKTCRRINYCALNKPGCEHECVNTEEGHYCRCRQGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEESFVCQCSEGFLINDDLKTCSRVDYCLLSDHGCEYSCVNTDRSFACQCPEGHALRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCRCFEGYILRDDGKTCRRKDVCQAVDHGCEHLCVNSGESYICKCLEGFGLAEDGKRCRRKDVCKSTHHGCEHICVNNGDFYTCRCSEGFVLAEDGRRCKRCTEGPIDLVFVIDGSKSLGEDNFEIVKHFVTGIIDSLAVSPKAARVGLLQYSTQVHTEFSLRDFSSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQVEGARPLSTRVPRVAIVFTDGRAQDDVSEWASKAKATGITMYAVGVGKAIEEELQEIASEPTGKHLFYAEDFSTMGEISGKLKQGICEALEDSDGRQDSPAEEPSKQVHQPTVQHRYLFEEDKLSRSTQKLFHSTKFSGSPLEESQDQCKCENLLTFQNLANEEVRKLTQRLEEMTQRMEALENRLRYR", "length": 936, "header": "tr|A0A8C2QNR7-1|A0A9J7H875_CRIGR Computationally mapped isoform of Matrilin-2 OS=Cricetulus griseus OX=10029 GN=Matn2 PE=4 SV=1 CANONICAL=A0A9J7H875-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H875-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H875/entry#A0A9J7H875-1", "sequence": { "sequence": "MEKMLVACLLMLGQFLLLPAGARDRPQARFPSRGRHVRTHPQTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFILDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKRKSDVERAVKRMRHLSTGTMTGLAIQYALNIAFSEVEGARPLRENVPRVIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDLNTLKAIGSEPHKDHVFLVANFSQIESLTSVFQNKLCAVHMCSVLEHDCAHFCINTPGSYTCRCKQGYILNSDQKTCRIQDLCATEDHGCEQLCVNVPGSFVCQCYSGYTLGQDGKRCAAVDFCASENHGCEHACVNAEGSYLCQCREGFALNPDKKTCTKIDHCASSNHGCQHECVNALTSAFCRCLKGFMLNPDRKTCRRINYCALNKPGCEHECVNTEEGHYCRCRQGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEESFVCQCSEGFLINDDLKTCSRVDYCLLSDHGCEYSCVNTDRSFACQCPEGHALRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCRCFEGYILRDDGKTCRRKDVCQAVDHGCEHLCVNSGESYICKCLEGFGLAEDGKRCRRKDVCKSTHHGCEHICVNNGDFYTCRCSEGFVLAEDGRRCKRCTEGPIDLVFVIDGSKSLGEDNFEIVKHFVTGIIDSLAVSPKAARVGLLQYSTQVHTEFSLRDFSSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQVEGARPLSTRVPRVAIVFTDGRAQDDVSEWASKAKATGITMYAVGVGKAIEEELQEIASEPTGKHLFYAEDFSTMGEISGKLKQGICEALEDSDGRQDSPAEEPSKQVHQPTESEPVTINIRDLLSCSNFAVQHRYLFEEDKLSRSTQKLFHSTKFSGSPLEESQDQCKCENLLTFQNLANEEVRKLTQRLEEMTQRMEALENRLRYR", "length": 955, "header": "tr|A0A9J7H875-1|A0A9J7H875_CRIGR Isoform 1 of Matrilin-2 OS=Cricetulus griseus OX=10029 GN=Matn2 PE=4 SV=1 CANONICAL=A0A9J7H875-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HA78-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H875/entry#A0A9J7HA78-1", "sequence": { "sequence": "MEKMLVACLLMLGQFLLLPAGARDRPQARFPSRGRHVRTHPQTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFILDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKRKSDVERAVKRMRHLSTGTMTGLAIQYALNIAFSEVEGARPLRENVPRVIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDLNTLKAIGSEPHKDHVFLVANFSQIESLTSVFQNKLCAVHMCSVLEHDCAHFCINTPGSYTCRCKQGYILNSDQKTCRIQDLCATEDHGCEQLCVNVPGSFVCQCYSGYTLGQDGKRCAAVDFCASENHGCEHACVNAEGSYLCQCREGFALNPDKKTCTRINYCALNKPGCEHECVNTEEGHYCRCRQGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEESFVCQCSEGFLINDDLKTCSRVDYCLLSDHGCEYSCVNTDRSFACQCPEGHALRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCRCFEGYILRDDGKTCRRKDVCQAVDHGCEHLCVNSGESYICKCLEGFGLAEDGKRCRRKDVCKSTHHGCEHICVNNGDFYTCRCSEGFVLAEDGRRCKRCTEGPIDLVFVIDGSKSLGEDNFEIVKHFVTGIIDSLAVSPKAARVGLLQYSTQVHTEFSLRDFSSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQVEGARPLSTRVPRVAIVFTDGRAQDDVSEWASKAKATGITMYAVGVGKAIEEELQEIASEPTGKHLFYAEDFSTMGEISGKLKQGICEALEDSDGRQDSPAEEPSKQVHQPTESEPVTINIRDLLSCSNFAVQHRYLFEEDKLSRSTQKLFHSTKFSGSPLEESQDQCKCENLLTFQNLANEEVRKLTQRLEEMTQRMEALENRLRYR", "length": 914, "header": "tr|A0A9J7HA78-1|A0A9J7HA78_CRIGR Computationally mapped isoform of Matrilin-2 OS=Cricetulus griseus OX=10029 GN=Matn2 PE=4 SV=1 CANONICAL=A0A9J7H875-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QNR7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNR7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QNR7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNR7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754409", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754409", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H875", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H875" } ], "pmid": "" }, { "name": "matrilin complex", "id": "GO:0120216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120216", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H875", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H875" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H875", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H875" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "response to axon injury", "id": "GO:0048678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048678", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H875", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H875" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H875", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H875" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 235, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 220, "end_pos": 222 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H9S3-1", "uniprot_ac": "A0A9J7H9S3", "uniprot_id": "A0A9J7H9S3_CRIGR", "mass": { "chemical_mass": 104457.0, "monoisotopic_mass": 104457.0 }, "refseq": { "ac": "XP_035308024", "name": "sal-like protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308024" }, "gene_names": [ { "name": "Sall2", "type": "recommended", "evidence": [ { "id": "A0A9J7H9S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3" } ] }, { "name": "Sall2", "type": "synonym", "evidence": [ { "id": "XP_035308024", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308024" } ] } ], "protein_names": [ { "name": "Sal-like protein 2", "type": "recommended", "evidence": [ { "id": "A0A9J7H9S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein Spalt-2", "type": "synonym", "evidence": [ { "id": "A0A9J7H9S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3/entry#names_and_taxonomy" } ] }, { "name": "sal-like protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035308024", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308024" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308024", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308024" } ] }, { "annotation": "Probable transcription factor that plays a role in eye development before, during, and after optic fissure closure.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EYB2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYB2#function" }, { "database": "UniProtKB", "id": "ARBA00060142", "url": "https://www.uniprot.org/uniprotkb/ARBA00060142#function" }, { "database": "UniProtKB", "id": "A0A9J7H9S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sall2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3", "locus": {} } ], "crossref": [ { "id": "A0A9J7H9S3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H9S3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20908", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20908", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774023", "url": "https://www.ncbi.nlm.nih.gov/gene/100774023", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774023", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774023", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H9S3", "url": "https://www.orthodb.org/?gene=A0A9J7H9S3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23233", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23233", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23233:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23233:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308024", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308024", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7EYB2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EYB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRRKQRRPQQLISDSEGPGASENGDANEEDHPQVCAKCCAQFSDPTEFLAHQNACCTDPPVMVIVGGQENPNNSSASSAPRPEGNSRPQVMDTEHSNHPDSGSSGPADPTWGPERRVEESSGHFLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLPLFSPIKPVQTGKTLAPSSSSSSSGAEPPKQAFFHLYHPLGSQHPFSVGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPGTTGLLAAQCLGAARGLEAAASPGLLKPKNGGGELGYGEVISSLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGAVERKPLVASTTALSATESLTLLSTGTSTAVAPGLPTFNKFVLMKAVEPKSKADENTPPGSEGSAITGVADSGTATRMQLSKLVTSLPSWALLTNHLKSTGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVASTASGAPTTSAPTPSSSSSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKTSPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGSTLPEGGGTAQENSSEQSTASGPGSFPQQQSQQPSPEEELSEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEVSGAEEEVGTVGAAPTTGKEMDSNEKAAQQASLPPPPPDNLDHTQPREQGTSDVSGGMEEEAKLEGTPSPTAAVTQEGEGTSTALVEELSLPEAVKKEPGEGSSRKACDVCGQTFPTQLALEEHQKTHPKEGPLFTCVFCRQGFLDRPTLKKHMLLAHHQVPPFAPHGPQNIATLSLVPGCSSSITSPGLSPFPRKDDPAIP", "length": 999, "header": "tr|A0A9J7H9S3-1|A0A9J7H9S3_CRIGR Isoform 1 of Sal-like protein 2 OS=Cricetulus griseus OX=10029 GN=Sall2 PE=3 SV=1 CANONICAL=A0A9J7H9S3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7EYB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3/entry#A0A9J7EYB2-1", "sequence": { "sequence": 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"length": 997, "header": "tr|A0A9J7EYB2-1|A0A9J7H9S3_CRIGR Computationally mapped isoform of Sal-like protein 2 OS=Cricetulus griseus OX=10029 GN=Sall2 PE=3 SV=1 CANONICAL=A0A9J7H9S3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3/entry#A0A9J7H9S3-1", "sequence": { "sequence": "MSRRKQRRPQQLISDSEGPGASENGDANEEDHPQVCAKCCAQFSDPTEFLAHQNACCTDPPVMVIVGGQENPNNSSASSAPRPEGNSRPQVMDTEHSNHPDSGSSGPADPTWGPERRVEESSGHFLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLPLFSPIKPVQTGKTLAPSSSSSSSGAEPPKQAFFHLYHPLGSQHPFSVGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPGTTGLLAAQCLGAARGLEAAASPGLLKPKNGGGELGYGEVISSLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGAVERKPLVASTTALSATESLTLLSTGTSTAVAPGLPTFNKFVLMKAVEPKSKADENTPPGSEGSAITGVADSGTATRMQLSKLVTSLPSWALLTNHLKSTGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVASTASGAPTTSAPTPSSSSSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKTSPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGSTLPEGGGTAQENSSEQSTASGPGSFPQQQSQQPSPEEELSEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEVSGAEEEVGTVGAAPTTGKEMDSNEKAAQQASLPPPPPDNLDHTQPREQGTSDVSGGMEEEAKLEGTPSPTAAVTQEGEGTSTALVEELSLPEAVKKEPGEGSSRKACDVCGQTFPTQLALEEHQKTHPKEGPLFTCVFCRQGFLDRPTLKKHMLLAHHQVPPFAPHGPQNIATLSLVPGCSSSITSPGLSPFPRKDDPAIP", "length": 999, "header": "tr|A0A9J7H9S3-1|A0A9J7H9S3_CRIGR Isoform 1 of Sal-like protein 2 OS=Cricetulus griseus OX=10029 GN=Sall2 PE=3 SV=1 CANONICAL=A0A9J7H9S3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 157, "start_aa": "Thr", "end_pos": 157, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr157", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 464, "start_aa": "Thr", "end_pos": 464, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr464", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 618, "start_aa": "Thr", "end_pos": 618, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr618", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 813, "start_aa": "Thr", "end_pos": 813, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr813", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 868, "start_aa": "Thr", "end_pos": 868, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr868", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EYB2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYB2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EYB2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYB2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774023", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774023", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 731, "end_pos": 733, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H9S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S3" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 370, "end_pos": 397, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 157, 464, 618, 813, 868 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 731, "end_pos": 733 }, { "start_pos": 73, "end_pos": 75 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H9V9-1", "uniprot_ac": "A0A9J7H9V9", "uniprot_id": "A0A9J7H9V9_CRIGR", "mass": { "chemical_mass": 369582.0, "monoisotopic_mass": 369582.0 }, "refseq": { "ac": "XP_035308096", "name": "cadherin-23 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308096" }, "gene_names": [ { "name": "Cdh23", "type": "recommended", "evidence": [ { "id": "A0A9J7H9V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V9" } ] }, { "name": "Cdh23", "type": "synonym", "evidence": [ { "id": "XP_035308096", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308096" } ] } ], "protein_names": [ { "name": "Cadherin-23", "type": "recommended", "evidence": [ { "id": "A0A9J7H9V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V9/entry#names_and_taxonomy" } ] }, { "name": "Otocadherin", "type": "synonym", "evidence": [ { "id": "A0A9J7H9V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V9/entry#names_and_taxonomy" } ] }, { "name": "cadherin-23 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_035308096", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308096" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308096" } ] }, { "annotation": "Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F015", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F015#function" }, { "database": "UniProtKB", "id": "ARBA00057485", "url": "https://www.uniprot.org/uniprotkb/ARBA00057485#function" }, { "database": "UniProtKB", "id": "A0A9J7KDX5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDX5#function" }, { "database": "UniProtKB", "id": "A0A9J7H9G2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9G2#function" }, { "database": "UniProtKB", "id": "A0A9J7H9V9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V9#function" }, { "database": "UniProtKB", "id": "A0A9J7HA44", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA44#function" }, { "database": "UniProtKB", "id": "A0A9J7J845", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J845#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9V9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cdh23", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V9", "locus": {} } ], "crossref": [ { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760032", "url": "https://www.ncbi.nlm.nih.gov/gene/100760032", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760032", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760032", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H9V9", "url": "https://www.orthodb.org/?gene=A0A9J7H9V9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24027:SF438", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24027:SF438", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308096", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7F015", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F015", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F015-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F015-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9G2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9V9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA44", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA44-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J845", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J845", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J845-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J845-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDX5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDX5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRYPTVTSLAVLWLLMLVSGSWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLARDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDSARGIVTVIRELDYEVTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRVITAVDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDEDVGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYNVSLYENITVGTSVLTVLATDNDVGTFGEVNYFFSDDPDRFSLDKDTGLIVLIARLDYELIQRFTLTVIARDGGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVNASAFGSYFDISVYEGYGVISVSRPLDYEQIPNGLIYLTVMAKDAGNPPLYSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNVTLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHVMLDRENPDPEEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGTPAGVSVYQVVAIDLDEGLNGLVSYRMQVGLPRMDFVINSTSGVVRTTAELDRERIAEYQLRVVASDAGTPTKSSTSTLTIRVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYTLVLEAIDNGPVGKRRTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIVQLKATDADEGEFGRVWYRILHGNHGNNFRIHISSGLLMRGPRPLDRERNSSHVLMVEAYNHDLGPMRSSVRVIVYVEDVNDEAPVFTQQQYNRLGLRETAGIGTSVIVVRATDRDTGDGGLVNYRILSGAEGKFEIDESTGLIVTVDYLDYETKTSYLMNVSATDRAPPFNQGFCSVYVTLLNELDEAVQFSNASYEAVIMENLALGTEIVRVQAYSIDNLNQITYRFDAYTSAQAKALFKIDAITGVITVKGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAISVPEDCPVGQRVATVKARDPDAGSNGQVVFSLASGNIAGAFEIVTSNDSIGEVFVAKPLDREELDHYILKVVASDCGTPPRKKDHILQVTILDVNDNPPVIESPFGYNVSVNENVGGGTSVVQVRATDRDIGINSVLSYYITEGNEDMTFRMDRISGEIATRPAPPDRERQNFYHLVVTVEDEGTPTLSATTHVYVTIVDENDNAPVFQQPHYEVVLDEGPDTVNASLITIQALDLDEGPNGTVTYAIVSGNTINTFRIDRHTGVITAAKELDYEISHGRYTLVVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFDVTEGQPGPRVWTFLAHDRDSGPNGQVEYSVMDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGVPPLSSTMLVGIRVLDINDNDPVLLNLPMNVTISENSPVSSFVAHVLASDADSGCNALLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIARKDFDLLLVYLADENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDMYAIVTYQLLGAHSELFDINNSTGVVTVRSGVVIDREAFSPPILELLLLAEDVGLLNGTAHLLVTILDDNDNWPTFSPAAYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPATGVIHVGNATIDREEQESYRLTVVATDRGTVPLSGTAIITILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANVTAIDLDLDPKLEYHIISIVAKDDTDCLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNILDVNDNTPQFKPFGITYYTERVLEGTTPGTTLIAVAAVDPDKGLNGLITYTLLDLTPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDVAVGTVILRVTATDADSGNFALIEYSLGDGEGKFAINPNTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNGQLTYSLEGPGMEAFFVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEYFTIDPVSGLIQTAQRLDREKQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFMRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEDKNFHLQPDGRLLVLRDLDREKEAVFSFIVKASSNRSWTPPRGPSPALDLLTDLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLVFYGILAIHYFRALANDSEDVGQVFTMGSVDGILRTFDLFMAYSPGYFVVDIVARDLAGHNDTAIIGIYILRDDQRVKIVINEIPDRVRGFEEEFIRLLSNITGAIVNTDDVQFHVDKKGRVNFAQTELLIHVVNRDTNRILDVDRVIQMIDENKEQLRNLFRNYNVLDVQPAISVRLPDDMSALQMAIIVLAILLFLAAMLFVLMNWYYRTVHKRKLKAIVAGSAGNRGFIDIMDMPNTNKYSFDGSNPVWLDPFCRNLELAAQAEHEDDLPENLSEIADLWNSPTRTHGTFGREPAAVKPDDDRYLRAAIQEYDNIAKLGQIIREGPIKGSLLKVVLEDYLRLKKLFAQRMVQKASSCHSSISELIHPELDEEPGDHSPGQGSLRFRHKPPMELKGPDGIHMVHGSTGTLLATDLNSLPEDDQKGLDRSLETLTASEATAFERNARTESAKSTPLHKLRDVIMESPLEITEL", "length": 3354, "header": "tr|A0A9J7H9V9-1|A0A9J7H9V9_CRIGR Isoform 1 of Cadherin-23 OS=Cricetulus griseus OX=10029 GN=Cdh23 PE=4 SV=1 CANONICAL=A0A9J7H9V9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F015-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V9/entry#A0A9J7F015-1", "sequence": { "sequence": "MRYPTVTSLAVLWLLMLVSGSWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLARDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDSARGIVTVIRELDYEVTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRVITAVDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYNVSLYENITVGTSVLTVLATDNDVGTFGEVNYFFSDDPDRFSLDKDTGLIVLIARLDYELIQRFTLTVIARDGGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVNASAFGSYFDISVYEGYGVISVSRPLDYEQIPNGLIYLTVMAKDAGNPPLYSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNVTLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHVMLDRENPDPEEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGTPAGVSVYQVVAIDLDEGLNGLVSYRMQVGLPRMDFVINSTSGVVRTTAELDRERIAEYQLRVVASDAGTPTKSSTSTLTIRVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYTLVLEAIDNGPVGKRRTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIVQLKATDADEGEFGRVWYRILHGNHGNNFRIHISSGLLMRGPRPLDRERNSSHVLMVEAYNHDLGPMRSSVRVIVYVEDVNDEAPVFTQQQYNRLGLRETAGIGTSVIVVRATDRDTGDGGLVNYRILSGAEGKFEIDESTGLIVTVDYLDYETKTSYLMNVSATDRAPPFNQGFCSVYVTLLNELDEAVQFSNASYEAVIMENLALGTEIVRVQAYSIDNLNQITYRFDAYTSAQAKALFKIDAITGVITVKGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAISVPEDCPVGQRVATVKARDPDAGSNGQVVFSLASGNIAGAFEIVTSNDSIGEVFVAKPLDREELDHYILKVVASDCGTPPRKKDHILQVTILDVNDNPPVIESPFGYNVSVNENVGGGTSVVQVRATDRDIGINSVLSYYITEGNEDMTFRMDRISGEIATRPAPPDRERQNFYHLVVTVEDEGTPTLSATTHVYVTIVDENDNAPVFQQPHYEVVLDEGPDTVNASLITIQALDLDEGPNGTVTYAIVSGNTINTFRIDRHTGVITAAKELDYEISHGRYTLVVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFDVTEGQPGPRVWTFLAHDRDSGPNGQVEYSVMDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGVPPLSSTMLVGIRVLDINDNDPVLLNLPMNVTISENSPVSSFVAHVLASDADSGCNALLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIARKDFDLLLVYLADENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDMYAIVTYQLLGAHSELFDINNSTGVVTVRSGVVIDREAFSPPILELLLLAEDVGLLNGTAHLLVTILDDNDNWPTFSPAAYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPATGVIHVGNATIDREEQESYRLTVVATDRGTVPLSGTAIITILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANVTAIDLDLDPKLEYHIISIVAKDDTDCLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNILDVNDNTPQFKPFGITYYTERVLEGTTPGTTLIAVAAVDPDKGLNGLITYTLLDLTPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDVAVGTVILRVTATDADSGNFALIEYSLGDGEGKFAINPNTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNGQLTYSLEGPGMEAFFVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEYFTIDPVSGLIQTAQRLDREKQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFMRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEDKNFHLQPDGRLLVLRDLDREKEAVFSFIVKASSNRSWTPPRGPSPALDLLTDLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLVFYGILAIHYFRALANDSEDVGQVFTMGSVDGILRTFDLFMAYSPGYFVVDIVARDLAGHNDTAIIGIYILRDDQRVKIVINEIPDRVRGFEEEFIRLLSNITGAIVNTDDVQFHVDKKGRVNFAQTELLIHVVNRDTNRILDVDRVIQMIDENKEQLRNLFRNYNVLDVQPAISVRLPDDMSALQMAIIVLAILLFLAAMLFVLMNWYYRTVHKRKLKAIVAGSAGNRGFIDIMDMPNTNKYSFDGANPVWLDPFCRNLELAAQAEHEDDLPENLSEIADLWNSPTRTHGTFGREPAAVKPDDDRYLRAAIQEYDNIAKLGQIIREGPIKLIHPELDEEPGDHSPGQGSLRFRHKPPMELKGPDGIHMVHGSTGTLLATDLNSLPEDDQKGLDRSLETLTASEATAFERNARTESAKSTPLHKLRDVIMESPLEITEL", "length": 3319, "header": "tr|A0A9J7F015-1|A0A9J7H9V9_CRIGR Computationally mapped isoform of Cadherin-23 OS=Cricetulus griseus OX=10029 GN=Cdh23 PE=4 SV=1 CANONICAL=A0A9J7H9V9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V9/entry#A0A9J7H9G2-1", "sequence": { "sequence": "MRYPTVTSLAVLWLLMLVSGSWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLARDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDSARGIVTVIRELDYEVTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRVITAVDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDEGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYNVSLYENITVGTSVLTVLATDNDVGTFGEVNYFFSDDPDRFSLDKDTGLIVLIARLDYELIQRFTLTVIARDGGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVNASAFGSYFDISVYEGYGVISVSRPLDYEQIPNGLIYLTVMAKDAGNPPLYSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNVTLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHVMLDRENPDPEEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGTPAGVSVYQVVAIDLDEGLNGLVSYRMQVGLPRMDFVINSTSGVVRTTAELDRERIAEYQLRVVASDAGTPTKSSTSTLTIRVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYTLVLEAIDNGPVGKRRTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIVQLKATDADEGEFGRVWYRILHGNHGNNFRIHISSGLLMRGPRPLDRERNSSHVLMVEAYNHDLGPMRSSVRVIVYVEDVNDEAPVFTQQQYNRLGLRETAGIGTSVIVVRATDRDTGDGGLVNYRILSGAEGKFEIDESTGLIVTVDYLDYETKTSYLMNVSATDRAPPFNQGFCSVYVTLLNELDEAVQFSNASYEAVIMENLALGTEIVRVQAYSIDNLNQITYRFDAYTSAQAKALFKIDAITGVITVKGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAISVPEDCPVGQRVATVKARDPDAGSNGQVVFSLASGNIAGAFEIVTSNDSIGEVFVAKPLDREELDHYILKVVASDCGTPPRKKDHILQVTILDVNDNPPVIESPFGYNVSVNENVGGGTSVVQVRATDRDIGINSVLSYYITEGNEDMTFRMDRISGEIATRPAPPDRERQNFYHLVVTVEDEGTPTLSATTHVYVTIVDENDNAPVFQQPHYEVVLDEGPDTVNASLITIQALDLDEGPNGTVTYAIVSGNTINTFRIDRHTGVITAAKELDYEISHGRYTLVVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFDVTEGQPGPRVWTFLAHDRDSGPNGQVEYSVMDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGVPPLSSTMLVGIRVLDINDNDPVLLNLPMNVTISENSPVSSFVAHVLASDADSGCNALLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIARKDFDLLLVYLADENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDMYAIVTYQLLGAHSELFDINNSTGVVTVRSGVVIDREAFSPPILELLLLAEDVGLLNGTAHLLVTILDDNDNWPTFSPAAYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPATGVIHVGNATIDREEQESYRLTVVATDRGTVPLSGTAIITILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANVTAIDLDLDPKLEYHIISIVAKDDTDCLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNILDVNDNTPQFKPFGITYYTERVLEGTTPGTTLIAVAAVDPDKGLNGLITYTLLDLTPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDVAVGTVILRVTATDADSGNFALIEYSLGDGEGKFAINPNTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNGQLTYSLEGPGMEAFFVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEYFTIDPVSGLIQTAQRLDREKQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFMRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEDKNFHLQPDGRLLVLRDLDREKEAVFSFIVKASSNRSWTPPRGPSPALDLLTDLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLVFYGILAIHYFRALANDSEDVGQVFTMGSVDGILRTFDLFMAYSPGYFVVDIVARDLAGHNDTAIIGIYILRDDQRVKIVINEIPDRVRGFEEEFIRLLSNITGAIVNTDDVQFHVDKKGRVNFAQTELLIHVVNRDTNRILDVDRVIQMIDENKEQLRNLFRNYNVLDVQPAISVRLPDDMSALQMAIIVLAILLFLAAMLFVLMNWYYRTVHKRKLKAIVAGSAGNRGFIDIMDMPNTNKYSFDGANPVWLDPFCRNLELAAQAEHEDDLPENLSEIADLWNSPTRTHGTFGREPAAVKPDDDRYLRAAIQEYDNIAKLGQIIREGPIKVGAPLQGPVHRPHLNLIPYSRMLGDVYLDLP", "length": 3240, "header": "tr|A0A9J7H9G2-1|A0A9J7H9G2_CRIGR Computationally mapped isoform of Cadherin-23 OS=Cricetulus griseus OX=10029 GN=Cdh23 PE=4 SV=1 CANONICAL=A0A9J7H9V9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V9/entry#A0A9J7H9V9-1", "sequence": { "sequence": "MRYPTVTSLAVLWLLMLVSGSWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLARDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDSARGIVTVIRELDYEVTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRVITAVDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDEDVGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYNVSLYENITVGTSVLTVLATDNDVGTFGEVNYFFSDDPDRFSLDKDTGLIVLIARLDYELIQRFTLTVIARDGGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVNASAFGSYFDISVYEGYGVISVSRPLDYEQIPNGLIYLTVMAKDAGNPPLYSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNVTLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHVMLDRENPDPEEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGTPAGVSVYQVVAIDLDEGLNGLVSYRMQVGLPRMDFVINSTSGVVRTTAELDRERIAEYQLRVVASDAGTPTKSSTSTLTIRVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYTLVLEAIDNGPVGKRRTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIVQLKATDADEGEFGRVWYRILHGNHGNNFRIHISSGLLMRGPRPLDRERNSSHVLMVEAYNHDLGPMRSSVRVIVYVEDVNDEAPVFTQQQYNRLGLRETAGIGTSVIVVRATDRDTGDGGLVNYRILSGAEGKFEIDESTGLIVTVDYLDYETKTSYLMNVSATDRAPPFNQGFCSVYVTLLNELDEAVQFSNASYEAVIMENLALGTEIVRVQAYSIDNLNQITYRFDAYTSAQAKALFKIDAITGVITVKGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAISVPEDCPVGQRVATVKARDPDAGSNGQVVFSLASGNIAGAFEIVTSNDSIGEVFVAKPLDREELDHYILKVVASDCGTPPRKKDHILQVTILDVNDNPPVIESPFGYNVSVNENVGGGTSVVQVRATDRDIGINSVLSYYITEGNEDMTFRMDRISGEIATRPAPPDRERQNFYHLVVTVEDEGTPTLSATTHVYVTIVDENDNAPVFQQPHYEVVLDEGPDTVNASLITIQALDLDEGPNGTVTYAIVSGNTINTFRIDRHTGVITAAKELDYEISHGRYTLVVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFDVTEGQPGPRVWTFLAHDRDSGPNGQVEYSVMDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGVPPLSSTMLVGIRVLDINDNDPVLLNLPMNVTISENSPVSSFVAHVLASDADSGCNALLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIARKDFDLLLVYLADENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDMYAIVTYQLLGAHSELFDINNSTGVVTVRSGVVIDREAFSPPILELLLLAEDVGLLNGTAHLLVTILDDNDNWPTFSPAAYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPATGVIHVGNATIDREEQESYRLTVVATDRGTVPLSGTAIITILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANVTAIDLDLDPKLEYHIISIVAKDDTDCLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNILDVNDNTPQFKPFGITYYTERVLEGTTPGTTLIAVAAVDPDKGLNGLITYTLLDLTPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDVAVGTVILRVTATDADSGNFALIEYSLGDGEGKFAINPNTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNGQLTYSLEGPGMEAFFVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEYFTIDPVSGLIQTAQRLDREKQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFMRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEDKNFHLQPDGRLLVLRDLDREKEAVFSFIVKASSNRSWTPPRGPSPALDLLTDLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLVFYGILAIHYFRALANDSEDVGQVFTMGSVDGILRTFDLFMAYSPGYFVVDIVARDLAGHNDTAIIGIYILRDDQRVKIVINEIPDRVRGFEEEFIRLLSNITGAIVNTDDVQFHVDKKGRVNFAQTELLIHVVNRDTNRILDVDRVIQMIDENKEQLRNLFRNYNVLDVQPAISVRLPDDMSALQMAIIVLAILLFLAAMLFVLMNWYYRTVHKRKLKAIVAGSAGNRGFIDIMDMPNTNKYSFDGSNPVWLDPFCRNLELAAQAEHEDDLPENLSEIADLWNSPTRTHGTFGREPAAVKPDDDRYLRAAIQEYDNIAKLGQIIREGPIKGSLLKVVLEDYLRLKKLFAQRMVQKASSCHSSISELIHPELDEEPGDHSPGQGSLRFRHKPPMELKGPDGIHMVHGSTGTLLATDLNSLPEDDQKGLDRSLETLTASEATAFERNARTESAKSTPLHKLRDVIMESPLEITEL", "length": 3354, "header": "tr|A0A9J7H9V9-1|A0A9J7H9V9_CRIGR Isoform 1 of Cadherin-23 OS=Cricetulus griseus OX=10029 GN=Cdh23 PE=4 SV=1 CANONICAL=A0A9J7H9V9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HA44-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V9/entry#A0A9J7HA44-1", "sequence": { "sequence": "MRYPTVTSLAVLWLLMLVSGSWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLARDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDSARGIVTVIRELDYEVTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRVITAVDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDEGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYNVSLYENITVGTSVLTVLATDNDVGTFGEVNYFFSDDPDRFSLDKDTGLIVLIARLDYELIQRFTLTVIARDGGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVNASAFGSYFDISVYEGYGVISVSRPLDYEQIPNGLIYLTVMAKDAGNPPLYSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNVTLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHVMLDRENPDPEEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGTPAGVSVYQVVAIDLDEGLNGLVSYRMQVGLPRMDFVINSTSGVVRTTAELDRERIAEYQLRVVASDAGTPTKSSTSTLTIRVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYTLVLEAIDNGPVGKRRTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIVQLKATDADEGEFGRVWYRILHGNHGNNFRIHISSGLLMRGPRPLDRERNSSHVLMVEAYNHDLGPMRSSVRVIVYVEDVNDEAPVFTQQQYNRLGLRETAGIGTSVIVVRATDRDTGDGGLVNYRILSGAEGKFEIDESTGLIVTVDYLDYETKTSYLMNVSATDRAPPFNQGFCSVYVTLLNELDEAVQFSNASYEAVIMENLALGTEIVRVQAYSIDNLNQITYRFDAYTSAQAKALFKIDAITGVITVKGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAISVPEDCPVGQRVATVKARDPDAGSNGQVVFSLASGNIAGAFEIVTSNDSIGEVFVAKPLDREELDHYILKVVASDCGTPPRKKDHILQVTILDVNDNPPVIESPFGYNVSVNENVGGGTSVVQVRATDRDIGINSVLSYYITEGNEDMTFRMDRISGEIATRPAPPDRERQNFYHLVVTVEDEGTPTLSATTHVYVTIVDENDNAPVFQQPHYEVVLDEGPDTVNASLITIQALDLDEGPNGTVTYAIVSGNTINTFRIDRHTGVITAAKELDYEISHGRYTLVVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFDVTEGQPGPRVWTFLAHDRDSGPNGQVEYSVMDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGVPPLSSTMLVGIRVLDINDNDPVLLNLPMNVTISENSPVSSFVAHVLASDADSGCNALLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIARKDFDLLLVYLADENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDMYAIVTYQLLGAHSELFDINNSTGVVTVRSGVVIDREAFSPPILELLLLAEDVGLLNGTAHLLVTILDDNDNWPTFSPAAYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPATGVIHVGNATIDREEQESYRLTVVATDRGTVPLSGTAIITILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANVTAIDLDLDPKLEYHIISIVAKDDTDCLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNILDVNDNTPQFKPFGITYYTERVLEGTTPGTTLIAVAAVDPDKGLNGLITYTLLDLTPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDVAVGTVILRVTATDADSGNFALIEYSLGDGEGKFAINPNTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNGQLTYSLEGPGMEAFFVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEYFTIDPVSGLIQTAQRLDREKQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFMRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEDKNFHLQPDGRLLVLRDLDREKEAVFSFIVKASSNRSWTPPRGPSPALDLLTDLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLVFYGILAIHYFRALANDSEDVGQVFTMGSVDGILRTFDLFMAYSPGYFVVDIVARDLAGHNDTAIIGIYILRDDQRVKIVINEIPDRVRGFEEEFIRLLSNITGAIVNTDDVQFHVDKKGRVNFAQTELLIHVVNRDTNRILDVDRVIQMIDENKEQLRNLFRNYNVLDVQPAISVRLPDDMSALQMAIIVLAILLFLAAMLFVLMNWYYRTVHKRKLKAIVAGSAGNRGFIDIMDMPNTNKYSFDGANPVWLDPFCRNLELAAQAEHEDDLPENLSEIADLWNSPTRTHGTFGREPAAVKPDDDRYLRAAIQEYDNIAKLGQIIREGPIKLIHPELDEEPGDHSPGQGSLRFRHKPPMELKGPDGIHMVHGSTGTLLATDLNSLPEDDQKGLDRSLETLTASEATAFERNARTESAKSTPLHKLRDVIMESPLEITEL", "length": 3317, "header": "tr|A0A9J7HA44-1|A0A9J7HA44_CRIGR Computationally mapped isoform of Cadherin-23 OS=Cricetulus griseus OX=10029 GN=Cdh23 PE=4 SV=1 CANONICAL=A0A9J7H9V9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J845-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V9/entry#A0A9J7J845-1", "sequence": { "sequence": "MRYPTVTSLAVLWLLMLVSGSWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLARDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDSARGIVTVIRELDYEVTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRVITAVDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYNVSLYENITVGTSVLTVLATDNDVGTFGEVNYFFSDDPDRFSLDKDTGLIVLIARLDYELIQRFTLTVIARDGGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVNASAFGSYFDISVYEGYGVISVSRPLDYEQIPNGLIYLTVMAKDAGNPPLYSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNVTLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHVMLDRENPDPEEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGTPAGVSVYQVVAIDLDEGLNGLVSYRMQVGLPRMDFVINSTSGVVRTTAELDRERIAEYQLRVVASDAGTPTKSSTSTLTIRVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYTLVLEAIDNGPVGKRRTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIVQLKATDADEGEFGRVWYRILHGNHGNNFRIHISSGLLMRGPRPLDRERNSSHVLMVEAYNHDLGPMRSSVRVIVYVEDVNDEAPVFTQQQYNRLGLRETAGIGTSVIVVRATDRDTGDGGLVNYRILSGAEGKFEIDESTGLIVTVDYLDYETKTSYLMNVSATDRAPPFNQGFCSVYVTLLNELDEAVQFSNASYEAVIMENLALGTEIVRVQAYSIDNLNQITYRFDAYTSAQAKALFKIDAITGVITVKGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAISVPEDCPVGQRVATVKARDPDAGSNGQVVFSLASGNIAGAFEIVTSNDSIGEVFVAKPLDREELDHYILKVVASDCGTPPRKKDHILQVTILDVNDNPPVIESPFGYNVSVNENVGGGTSVVQVRATDRDIGINSVLSYYITEGNEDMTFRMDRISGEIATRPAPPDRERQNFYHLVVTVEDEGTPTLSATTHVYVTIVDENDNAPVFQQPHYEVVLDEGPDTVNASLITIQALDLDEGPNGTVTYAIVSGNTINTFRIDRHTGVITAAKELDYEISHGRYTLVVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFDVTEGQPGPRVWTFLAHDRDSGPNGQVEYSVMDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGVPPLSSTMLVGIRVLDINDNDPVLLNLPMNVTISENSPVSSFVAHVLASDADSGCNALLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIARKDFDLLLVYLADENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDMYAIVTYQLLGAHSELFDINNSTGVVTVRSGVVIDREAFSPPILELLLLAEDVGLLNGTAHLLVTILDDNDNWPTFSPAAYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPATGVIHVGNATIDREEQESYRLTVVATDRGTVPLSGTAIITILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANVTAIDLDLDPKLEYHIISIVAKDDTDCLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNILDVNDNTPQFKPFGITYYTERVLEGTTPGTTLIAVAAVDPDKGLNGLITYTLLDLTPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDVAVGTVILRVTATDADSGNFALIEYSLGDGEGKFAINPNTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNGQLTYSLEGPGMEAFFVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEYFTIDPVSGLIQTAQRLDREKQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFMRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEDKNFHLQPDGRLLVLRDLDREKEAVFSFIVKASSNRSWTPPRGPSPALDLLTDLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLVFYGILAIHYFRALANDSEDVGQVFTMGSVDGILRTFDLFMAYSPGYFVVDIVARDLAGHNDTAIIGIYILRDDQRVKIVINEIPDRVRGFEEEFIRLLSNITGAIVNTDDVQFHVDKKGRVNFAQTELLIHVVNRDTNRILDVDRVIQMIDENKEQLRNLFRNYNVLDVQPAISVRLPDDMSALQMAIIVLAILLFLAAMLFVLMNWYYRTVHKRKLKAIVAGSAGNRGFIDIMDMPNTNKYSFDGANPVWLDPFCRNLELAAQAEHEDDLPENLSEIADLWNSPTRTHGTFGREPAAVKPDDDRYLRAAIQEYDNIAKLGQIIREGPIKGSLLKVVLEDYLRLKKLFAQRMVQKASSCHSSISELIHPELDEEPGDHSPGQGSLRFRHKPPMELKGPDGIHMVHGSTGTLLATDLNSLPEDDQKGLDRSLETLTASEATAFERNARTESAKSTPLHKLRDVIMESPLEITEL", "length": 3354, "header": "tr|A0A9J7J845-1|A0A9J7J845_CRIGR Computationally mapped isoform of Cadherin-23 OS=Cricetulus griseus OX=10029 GN=Cdh23 PE=4 SV=1 CANONICAL=A0A9J7H9V9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KDX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V9/entry#A0A9J7KDX5-1", "sequence": { "sequence": "MRYPTVTSLAVLWLLMLVSGSWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLARDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDSARGIVTVIRELDYEVTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRVITAVDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDEGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYNVSLYENITVGTSVLTVLATDNDVGTFGEVNYFFSDDPDRFSLDKDTGLIVLIARLDYELIQRFTLTVIARDGGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVNASAFGSYFDISVYEGYGVISVSRPLDYEQIPNGLIYLTVMAKDAGNPPLYSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNVTLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHVMLDRENPDPEEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGTPAGVSVYQVVAIDLDEGLNGLVSYRMQVGLPRMDFVINSTSGVVRTTAELDRERIAEYQLRVVASDAGTPTKSSTSTLTIRVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYTLVLEAIDNGPVGKRRTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIVQLKATDADEGEFGRVWYRILHGNHGNNFRIHISSGLLMRGPRPLDRERNSSHVLMVEAYNHDLGPMRSSVRVIVYVEDVNDEAPVFTQQQYNRLGLRETAGIGTSVIVVRATDRDTGDGGLVNYRILSGAEGKFEIDESTGLIVTVDYLDYETKTSYLMNVSATDRAPPFNQGFCSVYVTLLNELDEAVQFSNASYEAVIMENLALGTEIVRVQAYSIDNLNQITYRFDAYTSAQAKALFKIDAITGVITVKGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAISVPEDCPVGQRVATVKARDPDAGSNGQVVFSLASGNIAGAFEIVTSNDSIGEVFVAKPLDREELDHYILKVVASDCGTPPRKKDHILQVTILDVNDNPPVIESPFGYNVSVNENVGGGTSVVQVRATDRDIGINSVLSYYITEGNEDMTFRMDRISGEIATRPAPPDRERQNFYHLVVTVEDEGTPTLSATTHVYVTIVDENDNAPVFQQPHYEVVLDEGPDTVNASLITIQALDLDEGPNGTVTYAIVSGNTINTFRIDRHTGVITAAKELDYEISHGRYTLVVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFDVTEGQPGPRVWTFLAHDRDSGPNGQVEYSVMDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGVPPLSSTMLVGIRVLDINDNDPVLLNLPMNVTISENSPVSSFVAHVLASDADSGCNALLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIARKDFDLLLVYLADENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDMYAIVTYQLLGAHSELFDINNSTGVVTVRSGVVIDREAFSPPILELLLLAEDVGLLNGTAHLLVTILDDNDNWPTFSPAAYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPATGVIHVGNATIDREEQESYRLTVVATDRGTVPLSGTAIITILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANVTAIDLDLDPKLEYHIISIVAKDDTDCLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNILDVNDNTPQFKPFGITYYTERVLEGTTPGTTLIAVAAVDPDKGLNGLITYTLLDLTPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDVAVGTVILRVTATDADSGNFALIEYSLGDGEGKFAINPNTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNGQLTYSLEGPGMEAFFVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEYFTIDPVSGLIQTAQRLDREKQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFMRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEDKNFHLQPDGRLLVLRDLDREKEAVFSFIVKASSNRSWTPPRGPSPALDLLTDLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLVFYGILAIHYFRALANDSEDVGQVFTMGSVDGILRTFDLFMAYSPGYFVVDIVARDLAGHNDTAIIGIYILRDDQRVKIVINEIPDRVRGFEEEFIRLLSNITGAIVNTDDVQFHVDKKGRVNFAQTELLIHVVNRDTNRILDVDRVIQMIDENKEQLRNLFRNYNVLDVQPAISVRLPDDMSALQMAIIVLAILLFLAAMLFVLMNWYYRTVHKRKLKAIVAGSAGNRGFIDIMDMPNTNKYSFDGANPVWLDPFCRNLELAAQAEHEDDLPENLSEIADLWNSPTRTHGTFGREPAAVKPDDDRYLRAAIQEYDNIAKLGQIIREGPIKGSLLKVVLEDYLRLKKLFAQRMVQKASSCHSSISELIHPELDEEPGDHSPGQGSLRFRHKPPMELKGPDGIHMVHGSTGTLLATDLNSLPEDDQKGLDRSLETLTASEATAFERNARTESAKSTPLHKLRDVIMESPLEITEL", "length": 3352, "header": "tr|A0A9J7KDX5-1|A0A9J7H9V9_CRIGR Computationally mapped isoform of Cadherin-23 OS=Cricetulus griseus OX=10029 GN=Cdh23 PE=4 SV=1 CANONICAL=A0A9J7H9V9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986/entry#names_and_taxonomy" } ] }, { "name": "Testis-specific gene A14 protein", "type": "synonym", "evidence": [ { "id": "A0A9J7H986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986/entry#names_and_taxonomy" } ] }, { "name": "centrosomal protein of 41 kDa isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027250840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250840" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613652.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027250840", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250840" } ] }, { "annotation": "Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F0E4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0E4#function" }, { "database": "UniProtKB", "id": "ARBA00055268", "url": "https://www.uniprot.org/uniprotkb/ARBA00055268#function" }, { "database": "UniProtKB", "id": "A0A9J7KAU3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAU3#function" }, { "database": "UniProtKB", "id": "A0A9J7H986", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986#function" }, { "database": "UniProtKB", "id": "A0A8C2LK55", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK55#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H986", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cep41", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986", "locus": {} } ], "crossref": [ { "id": "A0A9J7H986", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H986", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00158", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00158", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757951", "url": "https://www.ncbi.nlm.nih.gov/gene/100757951", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757951", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757951", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TMCQRGF", "url": "https://omabrowser.org/oma/group/TMCQRGF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LK55", "url": "https://www.orthodb.org/?gene=A0A8C2LK55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7F0E4", "url": "https://www.orthodb.org/?gene=A0A9J7F0E4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H986", "url": "https://www.orthodb.org/?gene=A0A9J7H986", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7KAU3", "url": "https://www.orthodb.org/?gene=A0A9J7KAU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44390:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44390:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027250840", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250840", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LK55", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LK55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F0E4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F0E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0E4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H986", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H986-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAU3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSWSAFSVSARDWSSRPPACMVSPLPSEPSPNYWQSLLTWTLIPLDKYLTRRIPQNPRYQHIKSRLDTGNSMTKYIEKLEEIKKNYRYKKDELFKRLKVTTFAQLVIQVASLSDQTLEVTAEEIQRLEDNDSATSEADAEIAAKTNGKESPGEQSPSPVQFINSTGTGDSSRSTLQSVISGVGELDVDKELVKKEEPSGKDKPYPDCPFLLLDVRDRDSYQQCHVVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDEDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLVTGSLPASCQQALPLGSARKRSSPKMPSLPAENKWRFTPEDLKKIECYLEADQGLTDNHSRMNQNNSSGRDLKVKAGHNGQNLPTGGPAGHCNPRTPNSGHLQGKPWK", "length": 410, "header": "tr|A0A9J7H986-1|A0A9J7H986_CRIGR Isoform 1 of Centrosomal protein of 41 kDa OS=Cricetulus griseus OX=10029 GN=Cep41 PE=3 SV=1 CANONICAL=A0A9J7H986-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LK55-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986/entry#A0A8C2LK55-1", "sequence": { "sequence": "MSARRHIGNPEYLTRRIPQNPRYQHIKSRLDTGNSMTKYIEKLEEIKKNYRYKKDELFKRLKVTTFAQLVIQVASLSDQTLEVTAEEIQRLEDNDSATSEADAEIAAKTNGKESPGEQSPSPVQFINSTGTGDSSRSTLQSVISGVGELDVDKELVKKEEPSGKDKPYPDCPFLLLDVRDRDSYQQCHVVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDEDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLVTGSLPASCQQALPLGSARKRSSPKMPSLPAENKWRFTPEDLKKIECYLEADQGLTDNHSRMNQNNSSGRDLKVKAGHNGQNLPTGGPAGHCNPRTPNSGHLQGKPWK", "length": 373, "header": "tr|A0A8C2LK55-1|A0A8C2LK55_CRIGR Computationally mapped isoform of Centrosomal protein of 41 kDa OS=Cricetulus griseus OX=10029 GN=Cep41 PE=3 SV=1 CANONICAL=A0A9J7H986-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F0E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986/entry#A0A9J7F0E4-1", "sequence": { "sequence": "MPSWSAFSVSARDWSSRPPACMYLTRRIPQNPRYQHIKSRLDTGNSMTKYIEKLEEIKKNYRYKKDELFKRLKVTTFAQLVIQVASLSDQTLEVTAEEIQRLEDNDSATSEADAEIAAKTNGKESPGEQSPSPVQFINSTGTGDSSRSTLQSVISGVGELDVDKELVKKEEPSGKDKPYPDCPFLLLDVRDRDSYQQCHVVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDEDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLVTGSLPASCQQALPLGSARKRSSPKMPSLPAENKWRFTPEDLKKIECYLEADQGLTDNHSRMNQNNSSGRDLKVKAGHNGQNLPTGGPAGHCNPRTPNSGHLQGKPWK", "length": 384, "header": "tr|A0A9J7F0E4-1|A0A9J7H986_CRIGR Computationally mapped isoform of Centrosomal protein of 41 kDa OS=Cricetulus griseus OX=10029 GN=Cep41 PE=3 SV=1 CANONICAL=A0A9J7H986-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H986-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986/entry#A0A9J7H986-1", "sequence": { "sequence": "MPSWSAFSVSARDWSSRPPACMVSPLPSEPSPNYWQSLLTWTLIPLDKYLTRRIPQNPRYQHIKSRLDTGNSMTKYIEKLEEIKKNYRYKKDELFKRLKVTTFAQLVIQVASLSDQTLEVTAEEIQRLEDNDSATSEADAEIAAKTNGKESPGEQSPSPVQFINSTGTGDSSRSTLQSVISGVGELDVDKELVKKEEPSGKDKPYPDCPFLLLDVRDRDSYQQCHVVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDEDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLVTGSLPASCQQALPLGSARKRSSPKMPSLPAENKWRFTPEDLKKIECYLEADQGLTDNHSRMNQNNSSGRDLKVKAGHNGQNLPTGGPAGHCNPRTPNSGHLQGKPWK", "length": 410, "header": "tr|A0A9J7H986-1|A0A9J7H986_CRIGR Isoform 1 of Centrosomal protein of 41 kDa OS=Cricetulus griseus OX=10029 GN=Cep41 PE=3 SV=1 CANONICAL=A0A9J7H986-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986/entry#A0A9J7KAU3-1", "sequence": { "sequence": "MTKYIEKLEEIKKNYRYKKDELFKRLKVTTFAQLVIQVASLSDQTLEVTAEEIQRLEDNDSATSEADAEIAAKTNGKESPGEQSPSPVQFINSTGTGDSSRSTLQSVISGVGELDVDKELVKKEEPSGKDKPYPDCPFLLLDVRDRDSYQQCHVVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDEDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLVTGSLPASCQQALPLGSARKRSSPKMPSLPAENKWRFTPEDLKKIECYLEADQGLTDNHSRMNQNNSSGRDLKVKAGHNGQNLPTGGPAGHCNPRTPNSGHLQGKPWK", "length": 338, "header": "tr|A0A9J7KAU3-1|A0A9J7H986_CRIGR Computationally mapped isoform of Centrosomal protein of 41 kDa OS=Cricetulus griseus OX=10029 GN=Cep41 PE=3 SV=1 CANONICAL=A0A9J7H986-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F0E4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0E4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F0E4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0E4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757951", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757951", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XT12-1", "protein_name": "Centrosomal protein 41", "gene_name": "CEP41", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "GIPSAYGQGRNAWGSREYLTRRIPQNPRYQHIKTRLDTGSSLTKYIEKLEEIKRNYRYRKDELFKRLKVTTFAQLVVQVASLSDETLEVTNEEIHKLEGGNSPASDADAELTAGTNGKGSPNGTPPSPVLFINNTGAGESYRSTLQSLISGVGELDIEKDTHKKADTQAKDTPYPDCPFLLLDVRDRDAYDQCHIVGAYSYPIAMLSRAMNPYTNSILEYKNAHGKIIILYDDDERLASQAATTMCERGFENLFMLSGGLKVLAQKVPEGLITGSLPISCQVAAPTGSARKKPVPKVPPTRAESKWRYSAEDLQKIKYYLEEEQLPSDTASRLSRGSSGRDSKATTARSSPSLPSTAGSRMLSRSSIQNRPWK", "length": 373 }, "evidence": [ { "id": "A0A9J7H986", "url": "https://omabrowser.org/oma/group/A0A9J7H986/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MUG2-1", "protein_name": "Centrosomal protein of 41 kDa", "gene_name": "CEP41", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSVRRHIGNPEYLTRRIPQNPRYQHVKSRLDTGNSMTKYIEKLEEIKKNYRYKKDELFKRLKVTTFAQLVIQVASLSDQTLEVTAEEIQRLEDNDSATSEPDAEITAKTNGNGSPGEQSPSPVQFINSEGAGDFSRSTLQSVISGVGELDLDKGLVKKTEPNTKDKPYPDCPFLLLDVRDRDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDDDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLITGSLPASCQQALPPGSARKRSSPKVPPLPAENKWRFTPEDLKKIEYYLEEDQGPADNPSRLSQANASGRDAKVPGTRSGQNLPAGGPASHQNPRSLGSGHLQGKPWK", "length": 373 }, "evidence": [ { "id": "A0A9J7H986", "url": "https://omabrowser.org/oma/group/A0A9J7H986/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6GQN0-1", "protein_name": "Centrosomal protein of 41 kDa", "gene_name": "cep41", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVKRGIGDSAFLKKKIPQNPKYQHVKTRLDTGSSLTKYMERLEEARKNYRYRKDELFKRLKVTTFAQLVIQVASVSDQNDNIKDEMAGLEDDVSIFSASPGLDCLSDQTNGSPQPNLPPPQTINIDESGDNGFSPRSTLQSVISGVGELDLDKNGQKTIRLSPVSTSNTTECPYPDCPYLLLDVRDRELYDQCHIVSAYSYPIATLSRTMNPYTKEVLDYKNASGKIIIVYDEDERIASQAATTMCERGFENLFMLSGGLKVVAQKFPEGMTTGSVPISCLPSPTGPAGRKRSAQHQTSQLAEKKWRFTAEDLDKIQHYLEEVFIPSETSSRLSSRMSTSSARSKASTVGSSRQGSSIAGSESARSRSSRPWK", "length": 374 }, "evidence": [ { "id": "A0A9J7H986", "url": "https://omabrowser.org/oma/group/A0A9J7H986/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q99NF3-1", "protein_name": "Centrosomal protein of 41 kDa", "gene_name": "Cep41", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSARRHIGNPEYLTRRIPQNPRYQHVKSRLDTGNSMTKYIEKLEEIKKNYRYKKDELFKRLKVTTFAQLVIQVASLSDQTLEVTAEEIQRLEDNDSATSEADAEIAAKTNGKGSPEEQSPSPVQFINSTGAGDSSRSTLQSVISGVGELDVDKGLVKKEEPNGKDKPYPDCPFLLLDVRDRDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDEDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLVTGSLPASCQQALPFGSVRKRRGPKMPALPAENKWRFTPEDLKKIECYLEEDQGPADNPSRLNQNNSAGKDSKVAACRGGQNLPTSCPASHSSPRTLTSGHLQGKPWK", "length": 373 }, "evidence": [ { "id": "A0A9J7H986", "url": "https://omabrowser.org/oma/group/A0A9J7H986/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BYV8-1", "protein_name": "Centrosomal protein of 41 kDa", "gene_name": "CEP41", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLRRHIGNPEYLMKRIPQNPRYQHIKSRLDTGNSMTKYTEKLEEIKKNYRYKKDELFKRLKVTTFAQLIIQVASLSDQTLEVTAEEIQRLEDNDSAASDPDAETTARTNGKGNPGEQSPSPEQFINNAGAGDSSRSTLQSVISGVGELDLDKGPVKKAEPHTKDKPYPDCPFLLLDVRDRDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDDDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLITGSLPASCQQALPPGSARKRSSPKGPPLPAENKWRFTPEDLKKIEYYLEEEQGPADHPSRLNQANSSGRESKVPGARSAQNLPGGGPASHSNPRSLSSGHLQGKPWK", "length": 373 }, "evidence": [ { "id": "A0A9J7H986", "url": "https://omabrowser.org/oma/group/A0A9J7H986/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H986", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H986", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H986", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H986", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H986", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H986" }, { "id": "PS50206", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50206" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rhodanese", "eco_id": "ECO_0000259", "start_pos": 206, "end_pos": 303, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 164, "end_pos": 166 }, { "start_pos": 360, "end_pos": 362 }, { "start_pos": 367, "end_pos": 369 }, { "start_pos": 368, "end_pos": 370 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H7S2-1", "uniprot_ac": "A0A9J7H7S2", "uniprot_id": "A0A9J7H7S2_CRIGR", "mass": { "chemical_mass": 142399.0, "monoisotopic_mass": 142399.0 }, "refseq": { "ac": "XP_035306699", "name": "liprin-alpha-2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306699" }, "gene_names": [ { "name": "LOC100752430", "type": "recommended", "evidence": [ { "id": "A0A9J7H7S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2" } ] }, { "name": "LOC100752430", "type": "synonym", "evidence": [ { "id": "XP_035306699", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306699" } ] } ], "protein_names": [ { "name": "Liprin-alpha-2 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H7S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2/entry#names_and_taxonomy" } ] }, { "name": "liprin-alpha-2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035306699", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306699" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306699", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306699" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100752430", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2", "locus": {} } ], "crossref": [ { "id": "cd09562", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09562", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09565", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09565", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09568", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09568", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752430", "url": "https://www.ncbi.nlm.nih.gov/gene/100752430", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037622", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037622", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752430", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752430", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H7S2", "url": "https://www.orthodb.org/?gene=A0A9J7H7S2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25526", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25526", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306699", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306699", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7F0W8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0W8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F0W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0W8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6Y4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA53", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA53-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAV5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HB01", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HB01-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KE06", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KE06-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLTGSKGADPPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELASANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDDTSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQMKMRTGSLIEPTISRTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLGGHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLSASLEPESLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLSKLGTQAEKDRRLKKNTSGHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDENDDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDVASSRLQRLDNSTVRTYSC", "length": 1250, "header": "tr|A0A9J7H7S2-1|A0A9J7H7S2_CRIGR Isoform 1 of Liprin-alpha-2 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100752430 PE=3 SV=1 CANONICAL=A0A9J7H7S2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F0W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2/entry#A0A9J7F0W8-1", "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLTGSKGADPPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELASANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDDTSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQMKMRTGSLIEPTISRTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLGGHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLSASLEPESLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLSKLGTQAEKDRRLKKNTSGHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDENDDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDVASSRLQRLDNSTVRTYSC", "length": 1244, "header": "tr|A0A9J7F0W8-1|A0A9J7H7S2_CRIGR Computationally mapped isoform of Liprin-alpha-2 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100752430 PE=3 SV=1 CANONICAL=A0A9J7H7S2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H6Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2/entry#A0A9J7H6Y4-1", "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLTGSKGADPPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELASANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDDTSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQMKMRTGSLIEPTISRTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLGGHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLSASLEPESLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLSKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDENDDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDVASSRLQRLDNSTVRTYSC", "length": 1247, "header": "tr|A0A9J7H6Y4-1|A0A9J7H6Y4_CRIGR Computationally mapped isoform of Liprin-alpha-2 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100752430 PE=3 SV=1 CANONICAL=A0A9J7H7S2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2/entry#A0A9J7H7S2-1", "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLTGSKGADPPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELASANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDDTSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQMKMRTGSLIEPTISRTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLGGHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLSASLEPESLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLSKLGTQAEKDRRLKKNTSGHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDENDDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDVASSRLQRLDNSTVRTYSC", "length": 1250, "header": "tr|A0A9J7H7S2-1|A0A9J7H7S2_CRIGR Isoform 1 of Liprin-alpha-2 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100752430 PE=3 SV=1 CANONICAL=A0A9J7H7S2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HA53-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2/entry#A0A9J7HA53-1", "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLTGSKGADPPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELASANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDDTSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQMKMRTGSLIEPTISRTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLGGHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLSASLEPESLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLSKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDENDDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDDVIFSVYTT", "length": 1237, "header": "tr|A0A9J7HA53-1|A0A9J7HA53_CRIGR Computationally mapped isoform of Liprin-alpha-2 isoform X8 OS=Cricetulus griseus OX=10029 GN=LOC100752430 PE=3 SV=1 CANONICAL=A0A9J7H7S2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2/entry#A0A9J7HAV5-1", "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLTGSKGADPPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELASANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDDTSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQMKMRTGSLIEPTISRTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLGGHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLSASLEPESLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLSKLGTQAEKDRRLKKNTSGHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDENDDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDDVIFSVYTT", "length": 1240, "header": "tr|A0A9J7HAV5-1|A0A9J7HAV5_CRIGR Computationally mapped isoform of Liprin-alpha-2 isoform X5 OS=Cricetulus griseus OX=10029 GN=LOC100752430 PE=3 SV=1 CANONICAL=A0A9J7H7S2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HB01-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2/entry#A0A9J7HB01-1", "sequence": { "sequence": "MKTLKKIKTQVRERLRVSLERVSALEEELASANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDDTSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQMKMRTGSLIEPTISRTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLGGHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLSASLEPESLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLSKLGTQAEKDRRLKKNTSGHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDENDDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDVASSRLQRLDNSTVRTYSC", "length": 1070, "header": "tr|A0A9J7HB01-1|A0A9J7HB01_CRIGR Computationally mapped isoform of Liprin-alpha-2 isoform X7 OS=Cricetulus griseus OX=10029 GN=LOC100752430 PE=3 SV=1 CANONICAL=A0A9J7H7S2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KE06-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2/entry#A0A9J7KE06-1", "sequence": { "sequence": "MEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELASANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDDTSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQMKMRTGSLIEPTISRTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLGGHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLSASLEPESLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLSKLGTQAEKDRRLKKNTSGHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDENDDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDVASSRLQRLDNSTVRTYSC", "length": 1150, "header": "tr|A0A9J7KE06-1|A0A9J7H7S2_CRIGR Computationally mapped isoform of Liprin-alpha-2 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100752430 PE=3 SV=1 CANONICAL=A0A9J7H7S2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 778, "start_aa": "Thr", "end_pos": 778, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr778", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F0W8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0W8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F0W8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0W8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752430", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752430", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1242, "end_pos": 1244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 815, "end_pos": 817, "annotation": "n_glycosylation_sequon" }, { "start_pos": 881, "end_pos": 883, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H7S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S2" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 901, "end_pos": 967, "start_aa": "Trp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 778 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1242, "end_pos": 1244 }, { "start_pos": 132, "end_pos": 134 }, { "start_pos": 258, "end_pos": 260 }, { "start_pos": 601, "end_pos": 603 }, { "start_pos": 815, "end_pos": 817 }, { "start_pos": 881, "end_pos": 883 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HBR3-1", "uniprot_ac": "A0A9J7HBR3", "uniprot_id": "A0A9J7HBR3_CRIGR", "mass": { "chemical_mass": 487355.0, "monoisotopic_mass": 487355.0 }, "refseq": { "ac": "XP_035307659", "name": "tenascin-X isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307659" }, "gene_names": [ { "name": "LOC100767397", "type": "recommended", "evidence": [ { "id": "A0A9J7HBR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBR3" } ] }, { "name": "LOC100767397", "type": "synonym", "evidence": [ { "id": "XP_035307659", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307659" } ] } ], "protein_names": [ { "name": "Tenascin-X isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7HBR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBR3/entry#names_and_taxonomy" } ] }, { "name": "tenascin-X isoform X3", "type": "synonym", "evidence": [ { "id": "XP_035307659", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307659" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307659", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307659" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBR3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100767397", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBR3", "locus": {} } ], "crossref": [ { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767397", "url": "https://www.ncbi.nlm.nih.gov/gene/100767397", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767397", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767397", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HBR3", "url": "https://www.orthodb.org/?gene=A0A9J7HBR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46708", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46708", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46708:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46708:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18720", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18720", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25024", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25024", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307659", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307659", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7F171", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F171", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F171-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F171-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAQCAWTSILTLLVWLGVARAGPFSPRSNVTLPAPRPPPQPGGPSSQLYEHTVEGGEKQVVFTHRINLPPSAGCGCPPGTEPPVPASEVQALKVRLEILEELVKGLKEHCSGGCCPTAAQAGTGQTDVRSLCSLHGVFDLSRCACSCEPGWGGPTCSDPTDTKTPTSSPPSASRTCPDDCNDQGRCVRGRCVCFPGYSGPSCGWPSCPGDCQGRGRCVQGACVCRAGFSGPDCSQRSCPRNCNQRGGCEDGRCVCDPGYSGDDCGVRSCPRGCSQRGRCEDGRCVCDPGYSGEDCGVRSCPRDCGEGGRCVDGRCVCWPGYSGEDCSTRTCPRDCRGRGRCEDGECICDPGYSGDDCGVRSCPRDCNQRGRCEDGRCVCWPGYTGADCGARACPRDCRGRGRCEDGVCVCHTGYSGEDCGVRSCPGDCNQRGRCEHGRCVCWPGYTGRDCGARACPGDCRGRGRCVDGRCVCNVGFTGEDCGSRRCPGDCRGHGHCEDGVCVCEAGYAGEDCGTRSCPSGCRGRGRCLDGLCLCDDGYAGEDCGVRRCPRDCSQHGVCQDGLCVCHAGYAGEDCGVRTCPADCNRRGRCEDGRCLCDPGYTGPACATRMCPGDCRGRGRCVQGVCLCYAGYSGEDCGQEEPPASACPGGCGPRELCREGQCVCVEGFRGPDCAIQTCPGDCRGRGECLQGRCICQDGYAGDDCGEEVPAIQNMRMHLLEETTVRTEWTRAPGPVDAYEIQFIPMTEGASPPFTARVPSSASAYDQRGLAPGQDYQVTVRALRGTSWGPPASKTITTMIDGPQDLRVVAVTPTTLDLSWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADRTQLTDLMPGVEYVVTVTAERGRAVSYPASIRANTEGSATEWHPRPSLPQPPRRPWGNLTAELGRFRGTVQDLERHLRAHGYPLRANQTYTSVARHIYEFLRRHQRAGAPASKPHQPHPTASPTQSTGKWDSNQGDVDPASDGAHLVTTARHPKPEVLGSAVDGALIVSLDGLRGQFERVVLRWRPLPPAEGPSGELTVDGSERTVRLPNLRPGTTYHVEVHGVRAGQTSKSYAFITTTGPSTTQGAQAPILILEHHPLGELQVLGRDKAGRLRVAWTAQPGTFSHFQLRMQVAEGPWAHEELLPGDVRQALVPPPPPGAPYKLLLQGITPGGKPSVPITYQGIMDRAEEQPGKPSVLPRLGELTVSSLTSDSLLLHWTVLEGEFDSFVIQYKDKDGPQVIPVEGPQRSAPVTSLEPGRKYRFILYGLIGKKKHGPLVAEAKILLQSDPSPGSPPRLGELWVTDPTPDSLHLSWTVPEGQFDSFLVQYRDKEGRPLVVPVEGPERSVVVSPLDPNHKYRFTLFGVANKKRYGPLTADGTTAPAKEEGFSEQPLLGELTVTGMTPDSLRLSWTVARGPFDSFVIQYKDAQGQPQTVPVAGDENEVTVPGLESNRKYKMNLYGLRGRQRVGPVSVVAKTAPPHIVDQPSSPPEPSTEAPQPLEKPRLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSTVGVTDSQPEEEIPPAIEPPLEPRLEELTVTGVTPNSVSLSWMVPEGQFDSFMVQYKDRDGQPQEVPVSSDQRKVTILDLDPARKYKMNFYGLHGRRRVGPLSVLAMTDTLPPAPPPATEAPKLEPRLGELMVTDVTPDSVGLLWTVPEGEFDSFMVQYKDRDGQPQVVPVAADQREVTIPGLEPSRKYKFLLFGLRDGRRRGQVSVETKTAARDDTSPGALPRLGELWVTDPTTDSLRLSWTVPEGHFDSFMVQFKDKGGPQVLPVDGHERTATITALDAGRKYRFLLYGLQGKKRFGPLTTEGTTEPMNTVDHTGVKAPPKPRLGEELRVTSVTQDSVDLSWTVSEGHFDSFVVQYKDRDGQSQVVPVEGGHREVRVSGLDPGHRYKLLLYGLRESKRVGPLSVIAVTGPKEATEAWTEVPTTSTPSVEPHLRELRVEEATPHSLRLSWVVTEGEFDSFEVQYTDRDGKLKVVSTEGDQSDVILTGLESDHRYLVTLYGFHDGHRVDSAQIEALTVPWEEEEPTEPPTVTPKPKPHLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHEGQRVGPVSTVGVTDPEEDAPSLKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHNGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSTVGVTDPEEETTTTQVVPTMTTKPPPERPRLGELTVADATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTIPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSTVGVTSPEEETTTTQVVPTTTPTKPILGELTVTDATPDSLRLSWTVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGHKYKMNLYGLHQGQRVGPVSTVGVTEEEAMTTQVVPTMTPEPPPKKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSTVGVTALLPTELPTEPRLGDLAVVEVTSSTVHLSWTVARGPFDSFLVQYKDAQGQPQTVPVSRDLGEVTVSGLDPARKYKFLLFGLQGGERHGPVSVDAKTDTKLLPRLGELTMTDVTQNSVGLSWTVPEGEFDSFLVQYKDRGGQLQVVPVPADEREVTIPSLEPNRKYKFLLYGLAGRKRLGPASVEGTTAPLEKAPQPRLGELSVTGETPDSLRLLWTVAQGPFDSFLVQYRDRDGQLQTVAAAADQNEVTIEGLQPRRKYKFLLYGLAGGKRLGPISALGVTAPEEDMSAPSPTEPPEAPRLGTLTVTEATPDSLRLSWGVARGPFESFVVQYQDTEGQRQALLVDGDQDKVLISGLEPSTSYKFFLYGLREGMRHGPISAEGTTGPVPAGQTPGDPGPRLSQLSVTDVTTSSLRLNWEAPLRAFDTFLIRFGVPSPSTLEPYPRPLVQRELMVPGTQRSAVLRDLHPGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSDIGETSARVDWVPPPSRVDSFKLSYQLADGGEPQSVLVDARTQTQILQGLMPDTRYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTDGSALLHWKPPHKPVDEYNVQVASPGAPPLQASAPGSAVDYALTDLAVDTNYTATVRGLRGPNFTSPASITFTTGLKPPQDLEAKEVTPRTALLTWTEPEVPPTGYLLSFDTPGGQIQEILLPAGTTSHRLLRLFPSTFYSAQLRAVWGESLTPPVSTSFTTGGLHIPFPRDCGEEMQNGPSASKTTTIFLNGNRERPLDVFCDMETDGGGWLVFQRRMDGQTDFWRDWEEYAHGFGNISREFWLGNEVLHSLTQAGDYSMRVDLRAGDEAVFAQYDFFRVDSAVENYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNNLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFQAPTRGS", "length": 4480, "header": "tr|A0A9J7HBR3-1|A0A9J7HBR3_CRIGR Isoform 1 of Tenascin-X isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100767397 PE=3 SV=1 CANONICAL=A0A9J7HBR3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F171-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBR3/entry#A0A9J7F171-1", "sequence": { "sequence": "MPAQCAWTSILTLLVWLGVARAGPFSPRSNVTLPAPRPPPQPGGPSSQLYEHTVEGGEKQVVFTHRINLPPSAGCGCPPGTEPPVPASEVQALKVRLEILEELVKGLKEHCSGGCCPTAAQAGTGQTDVRSLCSLHGVFDLSRCACSCEPGWGGPTCSDPTDTKTPTSSPPSASRTCPDDCNDQGRCVRGRCVCFPGYSGPSCGWPSCPGDCQGRGRCVQGACVCRAGFSGPDCSQRSCPRNCNQRGGCEDGRCVCDPGYSGDDCGVRSCPRGCSQRGRCEDGRCVCDPGYSGEDCGVRSCPRDCGEGGRCVDGRCVCWPGYSGEDCSTRTCPRDCRGRGRCEDGECICDPGYSGDDCGVRSCPRDCNQRGRCEDGRCVCWPGYTGADCGARACPRDCRGRGRCEDGVCVCHTGYSGEDCGVRSCPGDCNQRGRCEHGRCVCWPGYTGRDCGARACPGDCRGRGRCVDGRCVCNVGFTGEDCGSRRCPGDCRGHGHCEDGVCVCEAGYAGEDCGTRSCPSGCRGRGRCLDGLCLCDDGYAGEDCGVRRCPRDCSQHGVCQDGLCVCHAGYAGEDCGVRTCPADCNRRGRCEDGRCLCDPGYTGPACATRMCPGDCRGRGRCVQGVCLCYAGYSGEDCGQEEPPASACPGGCGPRELCREGQCVCVEGFRGPDCAIQTCPGDCRGRGECLQGRCICQDGYAGDDCGEEVPAIQNMRMHLLEETTVRTEWTRAPGPVDAYEIQFIPMTEGASPPFTARVPSSASAYDQRGLAPGQDYQVTVRALRGTSWGPPASKTITTMIDGPQDLRVVAVTPTTLDLSWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADRTQLTDLMPGVEYVVTVTAERGRAVSYPASIRANTDRAEEQPGKPSVLPRLGELTVSSLTSDSLLLHWTVLEGEFDSFVIQYKDKDGPQVIPVEGPQRSAPVTSLEPGRKYRFILYGLIGKKKHGPLVAEAKILLQSDPSPGSPPRLGELWVTDPTPDSLHLSWTVPEGQFDSFLVQYRDKEGRPLVVPVEGPERSVVVSPLDPNHKYRFTLFGVANKKRYGPLTADGTTAPAKEEGFSEQPLLGELTVTGMTPDSLRLSWTVARGPFDSFVIQYKDAQGQPQTVPVAGDENEVTVPGLESNRKYKMNLYGLRGRQRVGPVSVVAKTAPPHIVDQPSSPPEPSTEAPQPLEKPRLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSTVGVTDSQPEEEIPPAIEPPLEPRLEELTVTGVTPNSVSLSWMVPEGQFDSFMVQYKDRDGQPQEVPVSSDQRKVTILDLDPARKYKMNFYGLHGRRRVGPLSVLAMTDTLPPAPPPATEAPKLEPRLGELMVTDVTPDSVGLLWTVPEGEFDSFMVQYKDRDGQPQVVPVAADQREVTIPGLEPSRKYKFLLFGLRDGRRRGQVSVETKTAARDDTSPGALPRLGELWVTDPTTDSLRLSWTVPEGHFDSFMVQFKDKGGPQVLPVDGHERTATITALDAGRKYRFLLYGLQGKKRFGPLTTEGTTEPMNTVDHTGVKAPPKPRLGEELRVTSVTQDSVDLSWTVSEGHFDSFVVQYKDRDGQSQVVPVEGGHREVRVSGLDPGHRYKLLLYGLRESKRVGPLSVIAVTGPKEATEAWTEVPTTSTPSVEPHLRELRVEEATPHSLRLSWVVTEGEFDSFEVQYTDRDGKLKVVSTEGDQSDVILTGLESDHRYLVTLYGFHDGHRVDSAQIEALTVPWEEEEPTEPPTVTPKPKPHLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHEGQRVGPVSTVGVTDPEEDAPSLKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHNGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSTVGVTDPEEETTTTQVVPTMTTKPPPERPRLGELTVADATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTIPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSTVGVTSPEEETTTTQVVPTTTPTKPILGELTVTDATPDSLRLSWTVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGHKYKMNLYGLHQGQRVGPVSTVGVTEEEAMTTQVVPTMTPEPPPKKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSTVGVTALLPTELPTEPRLGDLAVVEVTSSTVHLSWTVARGPFDSFLVQYKDAQGQPQTVPVSRDLGEVTVSGLDPARKYKFLLFGLQGGERHGPVSVDAKTDTKLLPRLGELTMTDVTQNSVGLSWTVPEGEFDSFLVQYKDRGGQLQVVPVPADEREVTIPSLEPNRKYKFLLYGLAGRKRLGPASVEGTTAPLEKAPQPRLGELSVTGETPDSLRLLWTVAQGPFDSFLVQYRDRDGQLQTVAAAADQNEVTIEGLQPRRKYKFLLYGLAGGKRLGPISALGVTAPEEDMSAPSPTEPPEAPRLGTLTVTEATPDSLRLSWGVARGPFESFVVQYQDTEGQRQALLVDGDQDKVLISGLEPSTSYKFFLYGLREGMRHGPISAEGTTGPVPAGQTPGDPGPRLSQLSVTDVTTSSLRLNWEAPLRAFDTFLIRFGVPSPSTLEPYPRPLVQRELMVPGTQRSAVLRDLHPGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSDIGETSARVDWVPPPSRVDSFKLSYQLADGGEPQSVLVDARTQTQILQGLMPDTRYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTDGSALLHWKPPHKPVDEYNVQVASPGAPPLQASAPGSAVDYALTDLAVDTNYTATVRGLRGPNFTSPASITFTTGLKPPQDLEAKEVTPRTALLTWTEPEVPPTGYLLSFDTPGGQIQEILLPAGTTSHRLLRLFPSTFYSAQLRAVWGESLTPPVSTSFTTGGLHIPFPRDCGEEMQNGPSASKTTTIFLNGNRERPLDVFCDMETDGGGWLVFQRRMDGQTDFWRDWEEYAHGFGNISREFWLGNEVLHSLTQAGDYSMRVDLRAGDEAVFAQYDFFRVDSAVENYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNNLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFQAPTRGS", "length": 4172, "header": "tr|A0A9J7F171-1|A0A9J7HBR3_CRIGR Computationally mapped isoform of Tenascin-X isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100767397 PE=3 SV=1 CANONICAL=A0A9J7HBR3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HBR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBR3/entry#A0A9J7HBR3-1", "sequence": { "sequence": "MPAQCAWTSILTLLVWLGVARAGPFSPRSNVTLPAPRPPPQPGGPSSQLYEHTVEGGEKQVVFTHRINLPPSAGCGCPPGTEPPVPASEVQALKVRLEILEELVKGLKEHCSGGCCPTAAQAGTGQTDVRSLCSLHGVFDLSRCACSCEPGWGGPTCSDPTDTKTPTSSPPSASRTCPDDCNDQGRCVRGRCVCFPGYSGPSCGWPSCPGDCQGRGRCVQGACVCRAGFSGPDCSQRSCPRNCNQRGGCEDGRCVCDPGYSGDDCGVRSCPRGCSQRGRCEDGRCVCDPGYSGEDCGVRSCPRDCGEGGRCVDGRCVCWPGYSGEDCSTRTCPRDCRGRGRCEDGECICDPGYSGDDCGVRSCPRDCNQRGRCEDGRCVCWPGYTGADCGARACPRDCRGRGRCEDGVCVCHTGYSGEDCGVRSCPGDCNQRGRCEHGRCVCWPGYTGRDCGARACPGDCRGRGRCVDGRCVCNVGFTGEDCGSRRCPGDCRGHGHCEDGVCVCEAGYAGEDCGTRSCPSGCRGRGRCLDGLCLCDDGYAGEDCGVRRCPRDCSQHGVCQDGLCVCHAGYAGEDCGVRTCPADCNRRGRCEDGRCLCDPGYTGPACATRMCPGDCRGRGRCVQGVCLCYAGYSGEDCGQEEPPASACPGGCGPRELCREGQCVCVEGFRGPDCAIQTCPGDCRGRGECLQGRCICQDGYAGDDCGEEVPAIQNMRMHLLEETTVRTEWTRAPGPVDAYEIQFIPMTEGASPPFTARVPSSASAYDQRGLAPGQDYQVTVRALRGTSWGPPASKTITTMIDGPQDLRVVAVTPTTLDLSWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADRTQLTDLMPGVEYVVTVTAERGRAVSYPASIRANTEGSATEWHPRPSLPQPPRRPWGNLTAELGRFRGTVQDLERHLRAHGYPLRANQTYTSVARHIYEFLRRHQRAGAPASKPHQPHPTASPTQSTGKWDSNQGDVDPASDGAHLVTTARHPKPEVLGSAVDGALIVSLDGLRGQFERVVLRWRPLPPAEGPSGELTVDGSERTVRLPNLRPGTTYHVEVHGVRAGQTSKSYAFITTTGPSTTQGAQAPILILEHHPLGELQVLGRDKAGRLRVAWTAQPGTFSHFQLRMQVAEGPWAHEELLPGDVRQALVPPPPPGAPYKLLLQGITPGGKPSVPITYQGIMDRAEEQPGKPSVLPRLGELTVSSLTSDSLLLHWTVLEGEFDSFVIQYKDKDGPQVIPVEGPQRSAPVTSLEPGRKYRFILYGLIGKKKHGPLVAEAKILLQSDPSPGSPPRLGELWVTDPTPDSLHLSWTVPEGQFDSFLVQYRDKEGRPLVVPVEGPERSVVVSPLDPNHKYRFTLFGVANKKRYGPLTADGTTAPAKEEGFSEQPLLGELTVTGMTPDSLRLSWTVARGPFDSFVIQYKDAQGQPQTVPVAGDENEVTVPGLESNRKYKMNLYGLRGRQRVGPVSVVAKTAPPHIVDQPSSPPEPSTEAPQPLEKPRLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSTVGVTDSQPEEEIPPAIEPPLEPRLEELTVTGVTPNSVSLSWMVPEGQFDSFMVQYKDRDGQPQEVPVSSDQRKVTILDLDPARKYKMNFYGLHGRRRVGPLSVLAMTDTLPPAPPPATEAPKLEPRLGELMVTDVTPDSVGLLWTVPEGEFDSFMVQYKDRDGQPQVVPVAADQREVTIPGLEPSRKYKFLLFGLRDGRRRGQVSVETKTAARDDTSPGALPRLGELWVTDPTTDSLRLSWTVPEGHFDSFMVQFKDKGGPQVLPVDGHERTATITALDAGRKYRFLLYGLQGKKRFGPLTTEGTTEPMNTVDHTGVKAPPKPRLGEELRVTSVTQDSVDLSWTVSEGHFDSFVVQYKDRDGQSQVVPVEGGHREVRVSGLDPGHRYKLLLYGLRESKRVGPLSVIAVTGPKEATEAWTEVPTTSTPSVEPHLRELRVEEATPHSLRLSWVVTEGEFDSFEVQYTDRDGKLKVVSTEGDQSDVILTGLESDHRYLVTLYGFHDGHRVDSAQIEALTVPWEEEEPTEPPTVTPKPKPHLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHEGQRVGPVSTVGVTDPEEDAPSLKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHNGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSTVGVTDPEEETTTTQVVPTMTTKPPPERPRLGELTVADATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTIPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSTVGVTSPEEETTTTQVVPTTTPTKPILGELTVTDATPDSLRLSWTVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGHKYKMNLYGLHQGQRVGPVSTVGVTEEEAMTTQVVPTMTPEPPPKKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDQVTIPGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSVVGVTAAEEETPSPTEPSTEAPEPREEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVVRVGGQEREATVRDLEPGRKYKMNLYGLHDGQRVGPVSTVGVTALLPTELPTEPRLGDLAVVEVTSSTVHLSWTVARGPFDSFLVQYKDAQGQPQTVPVSRDLGEVTVSGLDPARKYKFLLFGLQGGERHGPVSVDAKTDTKLLPRLGELTMTDVTQNSVGLSWTVPEGEFDSFLVQYKDRGGQLQVVPVPADEREVTIPSLEPNRKYKFLLYGLAGRKRLGPASVEGTTAPLEKAPQPRLGELSVTGETPDSLRLLWTVAQGPFDSFLVQYRDRDGQLQTVAAAADQNEVTIEGLQPRRKYKFLLYGLAGGKRLGPISALGVTAPEEDMSAPSPTEPPEAPRLGTLTVTEATPDSLRLSWGVARGPFESFVVQYQDTEGQRQALLVDGDQDKVLISGLEPSTSYKFFLYGLREGMRHGPISAEGTTGPVPAGQTPGDPGPRLSQLSVTDVTTSSLRLNWEAPLRAFDTFLIRFGVPSPSTLEPYPRPLVQRELMVPGTQRSAVLRDLHPGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSDIGETSARVDWVPPPSRVDSFKLSYQLADGGEPQSVLVDARTQTQILQGLMPDTRYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTDGSALLHWKPPHKPVDEYNVQVASPGAPPLQASAPGSAVDYALTDLAVDTNYTATVRGLRGPNFTSPASITFTTGLKPPQDLEAKEVTPRTALLTWTEPEVPPTGYLLSFDTPGGQIQEILLPAGTTSHRLLRLFPSTFYSAQLRAVWGESLTPPVSTSFTTGGLHIPFPRDCGEEMQNGPSASKTTTIFLNGNRERPLDVFCDMETDGGGWLVFQRRMDGQTDFWRDWEEYAHGFGNISREFWLGNEVLHSLTQAGDYSMRVDLRAGDEAVFAQYDFFRVDSAVENYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNNLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFQAPTRGS", "length": 4480, "header": "tr|A0A9J7HBR3-1|A0A9J7HBR3_CRIGR Isoform 1 of Tenascin-X isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100767397 PE=3 SV=1 CANONICAL=A0A9J7HBR3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 156, "start_aa": "Thr", "end_pos": 156, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr156", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1608, "start_aa": "Thr", "end_pos": 1608, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1608", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2128, "start_aa": "Thr", "end_pos": 2128, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2128", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2333, "start_aa": "Thr", "end_pos": 2333, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2333", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2537, "start_aa": "Thr", "end_pos": 2537, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2537", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2645, "start_aa": "Thr", "end_pos": 2645, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2645", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2860, "start_aa": "Thr", "end_pos": 2860, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2860", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3073, "start_aa": "Thr", "end_pos": 3073, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3073", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3288, "start_aa": "Thr", "end_pos": 3288, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3288", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3396, "start_aa": "Thr", "end_pos": 3396, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3396", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3787, "start_aa": "Thr", "end_pos": 3787, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3787", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 811, "start_aa": "Thr", "end_pos": 811, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr811", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F171", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F171" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"MSNSNTTQETLEIMKESEKKLVEESVNKSKFITKTPSKEEVEKEGEDAGLRQETQRRTSSHGHARKRAKSNSKLKLVRSLAVCEESSTPFADGPLDTQDIIQLHISCPSDKEEEKSTKDVSEKEDKDKSKEKVPRKMLSRDSSQEYTDSTGIDLHEFLVNTLKKNPRDRMMLLKLEQEILEFISDNNNQFKKFPQMTSYHRMLLHRVAAYFGMDHNVDQTGKAVIINKTSNTRIPEQRFSEHIKDEKNTEFQQRFILKRDDASMDREDNQIRVPLQDGRRSKSIEEREEEYQRARERIFARETGQNGYLSDVRLSKEAFSSSSHKRRQIFRGNREGLSRTSSSRQSSTDSELRSLEPRPWSSTDSDGSVRSMRPPVTKASSFSGISILTRGDSSKGGSAGRISRPGMALGAPEVCNQATSPQSVRGLLPCTAQQQQQQQQQQQLPALPPTPQQPTPLNNHMISQADDLSNPFGQMSLSRQGSTEAADPSSALFQPPLISQHPQQTSFIMASAGQPLPSSNYSTSSHAPPTQQVLPPQGYMPPPQQIQVSYYPPGQYPNSNQQYRPLSHPVAYSPQRGQQLPQPSQQPGLQPMMPNQQQTAYQGMLGVQQPQNQGLLSNQRSSMGGQMQGLVVQYTPLPSYQVPVGSDSQSVVQPPFQQPMLVPASQSVQGGLPAGGVPVYYSMITPAQQNGTSPSVGFLQPPGSEQYQMPQSPSPCSPPQVPQQYSGVSPSGPGVVVMQLNVPNGPQAPQNPSMVQWSHCKYYNVDQRGQKPGDLYNPDGGPQANAQMGSSPVTSPTQSPAPSPVTSLSNVCTGLGPLPVLTPFPRPGGPAQGRDLDQGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRAKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADKLFTQLAMSGAKIQWLKDAQGLPGAGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSLQRLKQIFKKGSPETTEMEPPPEPQANGEAVGAGGGPIYYIYEEEEEEEEEEEPPPEPPQLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFRRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRVGVIMANKERKKGQADKKNPLAAMMEEEPESARPEEGKPQDEPWSSSESRFGIVYGFLSCSHHPPPALHTETDTQKPVNSSPEELVKGRETYFPPYSLPTPQHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPADFLEEI", "length": 1373, "header": "tr|A0A9J7H8R0-1|A0A9J7H8R0_CRIGR Isoform 1 of SH3 and cysteine-rich domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=LOC100755585 PE=4 SV=1 CANONICAL=A0A9J7H8R0-1" }, "isoforms": [ { "isoform_ac": "A0A061IMQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8R0/entry#A0A061IMQ2-1", "sequence": { "sequence": "MSNSNTTQETLEIMKESEKKLVEESVNKSKFITKTPSKEEVEKEGEDAGLRQETQRRTSSHGHARKRAKSNSKLKLVRSLAVCEESSTPFADGPLDTQDIIQLHISCPSDKEEEKSTKDVSEKEDKDKSKEKVPRKMLSRDSSQEYTDSTGIDLHEFLVNTLKKNPRDRMMLLKLEQEILEFISDNNNQFKKFPQMTSYHRMLLHRVAAYFGMDHNVDQTGKAVIINKTSNTRIPEQRFSEHIKDEKNTEFQQRFILKRDDASMDREDNQIRVPLQDGRRSKSIEEREEEYQRARERIFARETGQNGYLSDVRLSKEAFSSSSHKRRQIFRGNREGLSRTSSSRQSSTDSELRSLEPRPWSSTDSDGSVRSMRPPVTKASSFSGISILTRGDSSKGGSAGRISRPGMALGAPEVCNQATSPQSVRGLLPCTAQQQQQQQQQQQLPALPPTPQQPTPLNNHMISQADDLSNPFGQMSLSRQGSTEAADPSSALFQPPLISQHPQQTSFIMASAGQPLPSSNYSTSSHAPPTQQVLPPQGYMPPPQQIQVSYYPPGQYPNSNQQYRPLSHPVAYSPQRGQQLPQPSQQPGLQPMMPNQQQTAYQGMLGVQQPQNQGLLSNQRSSMGGQMQGLVVQYTPLPSYQVPVGSDSQSVVQPPFQQPMLVPASQSVQGGLPAGGVPVYYSMITPAQQNGTSPSVGFLQPPGSEQYQMPQSPSPCSPPQVPQQYSGVSPSGPGVVVMQLNVPNGPQAPQNPSMVQWSHCKYYNVDQRGQKPGDLYNPDGGPQANAQMGSSPVTSPTQSPAPSPVTSLSNVCTGLGPLPVLTPFPRPGGPAQGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRAKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADKLFTQLAMSGAKIQWLKDAQGLPGAGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRVAKKNYDLRILERASSQ", "length": 1006, "header": "tr|A0A061IMQ2-1|A0A9J7H8R0_CRIGR Computationally mapped isoform of SH3 and cysteine-rich domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=LOC100755585 PE=4 SV=1 CANONICAL=A0A9J7H8R0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F2X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8R0/entry#A0A9J7F2X1-1", "sequence": { "sequence": "MPPFASTTLMTEKEVLESPKPPFPAETPQSGLQRLKQIFKKGSPETTEMEPPPEPQANGEAVGAGGGPIYYIYEEEEEEEEEEEPPPEPPQLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFRRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRVGVIMANKERKKGQADKKNPLAAMMEEEPESARPEEGKPQDGNNAERDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPADFLEEI", "length": 373, "header": "tr|A0A9J7F2X1-1|A0A9J7H8R0_CRIGR Computationally mapped isoform of SH3 and cysteine-rich domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=LOC100755585 PE=4 SV=1 CANONICAL=A0A9J7H8R0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F4X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8R0/entry#A0A9J7F4X3-1", "sequence": { "sequence": "MSNSNTTQETLEIMKESEKKLVEESVNKSKFITKTPSKEEVEKEGEDAGLRQETQRRTSSHGHARKRAKSNSKLKLVRSLAVCEESSTPFADGPLDTQDIIQLHISCPSDKEEEKSTKDVSEKEDKDKSKEKVPRKMLSRDSSQEYTDSTGIDLHEFLVNTLKKNPRDRMMLLKLEQEILEFISDNNNQFKKFPQMTSYHRMLLHRVAAYFGMDHNVDQTGKAVIINKTSNTRIPEQRFSEHIKDEKNTEFQQRFILKRDDASMDREDNQTGQNGYLSDVRGNREGLSRTSSSRQSSTDSELRSLEPRPWSSTDSDGSVRSMRPPVTKASSFSGISILTRGDSSKGGSAGRISRPGMALGAPEVCNQATSPQSVRGLLPCTAQQQQQQQQQQQLPALPPTPQQPTPLNNHMISQADDLSNPFGQMSLSRQGSTEAADPSSALFQPPLISQHPQQTSFIMASAGQPLPSSNYSTSSHAPPTQQVLPPQGYMPPPQQIQVSYYPPGQYPNSNQQYRPLSHPVAYSPQRGQQLPQPSQQPGLQPMMPNQQQTAYQGMLGVQQPQNQGLLSNQRSSMGGQMQGLVVQYTPLPSYQVPVGSDSQSVVQPPFQQPMLVPASQSVQGGLPAGGVPVYYSMITPAQQNGTSPSVGFLQPPGSEQYQMPQSPSPCSPPQVPQQYSGVSPSGPGVVVMQLNVPNGPQAPQNPSMVQWSHCKYYNVDQRGQKPGDLYNPDGGPQANAQMGSSPVTSPTQSPAPSPVTSLSNVCTGLGPLPVLTPFPRPGGPAQGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRAKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADKLFTQLAMSGAKIQWLKDAQGLPGAGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRVAKKNYDLRILERASSQ", "length": 956, "header": "tr|A0A9J7F4X3-1|A0A9J7H8R0_CRIGR Computationally mapped isoform of SH3 and cysteine-rich domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=LOC100755585 PE=4 SV=1 CANONICAL=A0A9J7H8R0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F508-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8R0/entry#A0A9J7F508-1", "sequence": { "sequence": "MSNSNTTQETLEIMKESEKKLVEESVNKSKFITKTPSKEEVEKEGEDAGLRQETQRRTSSHGHARKRAKSNSKLKLVRSLAVCEESSTPFADGPLDTQDIIQLHISCPSDKEEEKSTKDVSEKEDKDKSKEKVPRKMLSRDSSQEYTDSTGIDLHEFLVNTLKKNPRDRMMLLKLEQEILEFISDNNNQFKKFPQMTSYHRMLLHRVAAYFGMDHNVDQTGKAVIINKTSNTRIPEQRFSEHIKDEKNTEFQQRFILKRDDASMDREDNQTGQNGYLSDVRLSKEAFSSSSHKRRQIFRGNREGLSRTSSSRQSSTDSELRSLEPRPWSSTDSDGSVRSMRPPVTKASSFSGISILTRGDSSKGGSAGRISRPGMALGAPEVCNQATSPQSVRGLLPCTAQQQQQQQQQQQLPALPPTPQQPTPLNNHMISQADDLSNPFGQMSLSRQGSTEAADPSSALFQPPLISQHPQQTSFIMASAGQPLPSSNYSTSSHAPPTQQVLPPQGYMPPPQQIQVSYYPPGQYPNSNQQYRPLSHPVAYSPQRGQQLPQPSQQPGLQPMMPNQQQTAYQGMLGVQQPQNQGLLSNQRSSMGGQMQGLVVQYTPLPSYQVPVGSDSQSVVQPPFQQPMLVPASQSVQGGLPAGGVPVYYSMITPAQQNGTSPSVGFLQPPGSEQYQMPQSPSPCSPPQVPQQYSGVSPSGPGVVVMQLNVPNGPQAPQNPSMVQWSHCKYYNVDQRGQKPGDLYNPDGGPQANAQMGSSPVTSPTQSPAPSPVTSLSNVCTGLGPLPVLTPFPRPGGPAQGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRAKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADKLFTQLAMSGAKIQWLKDAQGLPGAGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRVAKKNYDLRILERASSQ", "length": 974, "header": "tr|A0A9J7F508-1|A0A9J7H8R0_CRIGR Computationally mapped isoform of SH3 and cysteine-rich domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=LOC100755585 PE=4 SV=1 CANONICAL=A0A9J7H8R0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H8R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8R0/entry#A0A9J7H8R0-1", "sequence": { "sequence": "MSNSNTTQETLEIMKESEKKLVEESVNKSKFITKTPSKEEVEKEGEDAGLRQETQRRTSSHGHARKRAKSNSKLKLVRSLAVCEESSTPFADGPLDTQDIIQLHISCPSDKEEEKSTKDVSEKEDKDKSKEKVPRKMLSRDSSQEYTDSTGIDLHEFLVNTLKKNPRDRMMLLKLEQEILEFISDNNNQFKKFPQMTSYHRMLLHRVAAYFGMDHNVDQTGKAVIINKTSNTRIPEQRFSEHIKDEKNTEFQQRFILKRDDASMDREDNQIRVPLQDGRRSKSIEEREEEYQRARERIFARETGQNGYLSDVRLSKEAFSSSSHKRRQIFRGNREGLSRTSSSRQSSTDSELRSLEPRPWSSTDSDGSVRSMRPPVTKASSFSGISILTRGDSSKGGSAGRISRPGMALGAPEVCNQATSPQSVRGLLPCTAQQQQQQQQQQQLPALPPTPQQPTPLNNHMISQADDLSNPFGQMSLSRQGSTEAADPSSALFQPPLISQHPQQTSFIMASAGQPLPSSNYSTSSHAPPTQQVLPPQGYMPPPQQIQVSYYPPGQYPNSNQQYRPLSHPVAYSPQRGQQLPQPSQQPGLQPMMPNQQQTAYQGMLGVQQPQNQGLLSNQRSSMGGQMQGLVVQYTPLPSYQVPVGSDSQSVVQPPFQQPMLVPASQSVQGGLPAGGVPVYYSMITPAQQNGTSPSVGFLQPPGSEQYQMPQSPSPCSPPQVPQQYSGVSPSGPGVVVMQLNVPNGPQAPQNPSMVQWSHCKYYNVDQRGQKPGDLYNPDGGPQANAQMGSSPVTSPTQSPAPSPVTSLSNVCTGLGPLPVLTPFPRPGGPAQGRDLDQGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRAKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADKLFTQLAMSGAKIQWLKDAQGLPGAGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSLQRLKQIFKKGSPETTEMEPPPEPQANGEAVGAGGGPIYYIYEEEEEEEEEEEPPPEPPQLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFRRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRVGVIMANKERKKGQADKKNPLAAMMEEEPESARPEEGKPQDEPWSSSESRFGIVYGFLSCSHHPPPALHTETDTQKPVNSSPEELVKGRETYFPPYSLPTPQHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPADFLEEI", "length": 1373, "header": "tr|A0A9J7H8R0-1|A0A9J7H8R0_CRIGR Isoform 1 of SH3 and cysteine-rich domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=LOC100755585 PE=4 SV=1 CANONICAL=A0A9J7H8R0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HCV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8R0/entry#A0A9J7HCV2-1", "sequence": { "sequence": "MSNSNTTQETLEIMKESEKKLVEESVNKSKFITKTPSKEEVEKEGEDAGLRQETQRRTSSHGHARKRAKSNSKLKLVRSLAVCEESSTPFADGPLDTQDIIQLHISCPSDKEEEKSTKDVSEKEDKDKSKEKVPRKMLSRDSSQEYTDSTGIDLHEFLVNTLKKNPRDRMMLLKLEQEILEFISDNNNQFKKFPQMTSYHRMLLHRVAAYFGMDHNVDQTGKAVIINKTSNTRIPEQRFSEHIKDEKNTEFQQRFILKRDDASMDREDNQIRVPLQDGRRSKSIEEREEEYQRARERIFARETGQNGYLSDVRLSKEAFSSSSHKRRQIFRGNREGLSRTSSSRQSSTDSELRSLEPRPWSSTDSDGSVRSMRPPVTKASSFSGISILTRGDSSKGGSAGRISRPGMALGAPEVCNQATSPQSVRGLLPCTAQQQQQQQQQQQLPALPPTPQQPTPLNNHMISQADDLSNPFGQMSLSRQGSTEAADPSSALFQPPLISQHPQQTSFIMASAGQPLPSSNYSTSSHAPPTQQVLPPQGYMPPPQQIQVSYYPPGQYPNSNQQYRPLSHPVAYSPQRGQQLPQPSQQPGLQPMMPNQQQTAYQGMLGVQQPQNQGLLSNQRSSMGGQMQGLVVQYTPLPSYQVPVGSDSQSVVQPPFQQPMLVPASQSVQGGLPAGGVPVYYSMITPAQQNGTSPSVGFLQPPGSEQYQMPQSPSPCSPPQVPQQYSGVSPSGPGVVVMQLNVPNGPQAPQNPSMVQWSHCKYYNVDQRGQKPGDLYNPDGGPQANAQMGSSPVTSPTQSPAPSPVTSLSNVCTGLGPLPVLTPFPRPGGPAQGRDLDQGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRAKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADKLFTQLAMSGAKIQWLKDAQGLPGAGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSLQRLKQIFKKGSPETTEMEPPPEPQANGEAVGAGGGPIYYIYEEEEEEEEEEEPPPEPPQLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFRRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRVGVIMANKERKKGQADKKNPLAAMMEEEPESARPEEGKPQDGNNAERDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPADFLEEI", "length": 1330, "header": "tr|A0A9J7HCV2-1|A0A9J7HCV2_CRIGR Computationally mapped isoform of SH3 and cysteine-rich domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=LOC100755585 PE=4 SV=1 CANONICAL=A0A9J7H8R0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JAM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8R0/entry#A0A9J7JAM3-1", "sequence": { "sequence": "MSNSNTTQETLEIMKESEKKLVEESVNKSKFITKTPSKEEVEKEGEDAGLRQETQRRTSSHGHARKRAKSNSKLKLVRSLAVCEESSTPFADGPLDTQDIIQLHISCPSDKEEEKSTKDVSEKEDKDKSKEKVPRKMLSRDSSQEYTDSTGIDLHEFLVNTLKKNPRDRMMLLKLEQEILEFISDNNNQFKKFPQMTSYHRMLLHRVAAYFGMDHNVDQTGKAVIINKTSNTRIPEQRFSEHIKDEKNTEFQQRFILKRDDASMDREDNQIRVPLQDGRRSKSIEEREEEYQRARERIFARETGQNGYLSDVRGNREGLSRTSSSRQSSTDSELRSLEPRPWSSTDSDGSVRSMRPPVTKASSFSGISILTRGDSSKGGSAGRISRPGMALGAPEVCNQATSPQSVRGLLPCTAQQQQQQQQQQQLPALPPTPQQPTPLNNHMISQADDLSNPFGQMSLSRQGSTEAADPSSALFQPPLISQHPQQTSFIMASAGQPLPSSNYSTSSHAPPTQQVLPPQGYMPPPQQIQVSYYPPGQYPNSNQQYRPLSHPVAYSPQRGQQLPQPSQQPGLQPMMPNQQQTAYQGMLGVQQPQNQGLLSNQRSSMGGQMQGLVVQYTPLPSYQVPVGSDSQSVVQPPFQQPMLVPASQSVQGGLPAGGVPVYYSMITPAQQNGTSPSVGFLQPPGSEQYQMPQSPSPCSPPQVPQQYSGVSPSGPGVVVMQLNVPNGPQAPQNPSMVQWSHCKYYNVDQRGQKPGDLYNPDGGPQANAQMGSSPVTSPTQSPAPSPVTSLSNVCTGLGPLPVLTPFPRPGGPAQGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRAKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADKLFTQLAMSGAKIQWLKDAQGLPGAGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRVAKKNYDLRILERASSQ", "length": 988, "header": "tr|A0A9J7JAM3-1|A0A9J7JAM3_CRIGR Computationally mapped isoform of R3H domain-containing protein 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=LOC100755585 PE=4 SV=1 CANONICAL=A0A9J7H8R0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 450, "start_aa": "Thr", "end_pos": 450, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr450", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F2X1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2X1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F2X1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2X1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755585", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755585", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "skeletal muscle contraction", "id": "GO:0003009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003009", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8R0" } ], "pmid": "" }, { "name": "positive regulation of protein localization to plasma membrane", "id": "GO:1903078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903078", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8R0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8R0" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8R0" } ], "pmid": "" }, { "name": "T-tubule", "id": "GO:0030315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030315", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8R0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8R0" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8R0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1226, "end_pos": 1228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 690, "end_pos": 692, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307833", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307833" } ] }, { "annotation": "Required for activity of the AHR. Upon ligand binding, AHR translocates into the nucleus, where it heterodimerizes with ARNT and induces transcription by binding to xenobiotic response elements (XRE). Not required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex initiates transcription of genes involved in the regulation of a variety of biological processes, including angiogenesis, hematopoiesis, drug and lipid metabolism, cell motility and immune modulation. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia. The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F627", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F627#function" }, { "database": "UniProtKB", "id": "ARBA00045949", "url": "https://www.uniprot.org/uniprotkb/ARBA00045949#function" }, { "database": "UniProtKB", "id": "A0A9J7KBG7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBG7#function" }, { "database": "UniProtKB", "id": "A0A9J7HBT2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBT2#function" }, { "database": "UniProtKB", "id": "A0A9J7H9V2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V2#function" }, { "database": "UniProtKB", "id": "A0A9J7HAI5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAI5#function" }, { "database": "UniProtKB", "id": "A0A9J7HC24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24#function" }, { "database": 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"categories": [ "Protein Classification" ] }, { "id": "100752106", "url": "https://www.ncbi.nlm.nih.gov/gene/100752106", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752106", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752106", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HC24", "url": "https://www.orthodb.org/?gene=A0A9J7HC24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J837", "url": "https://www.orthodb.org/?gene=A0A9J7J837", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23042", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23042", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307833", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307833", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7F627", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F627", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F627-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F627-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9V2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V2", "database": "UniProtKB", 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"MPVGLCEKGKSMSSLPGCVSLDAATAAPDSEDMTELQQAVVEELGISMEELRQFIDEMLEKMDCIQQRKKQLAELETWSLQKESEVAYVDQLLDDASRAVINCESLVKDFYSKLGLRYHHCSSEDEASQPTEIIEIPDEDDDVLSIDSGDAGSRSPKDQLREAMAALRKSAQDVQKFMDAVNKKSSSQDLNKEMTSDVPSLGPTIASGNPGPGIQGGGAVVQRAIKRRSGLDFDDDGEGNSKFLRCDDEQMCNDKERFARSDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNSSVDPVCMNRLSFLRNRCRNGLGSAKEGEPHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNICQPTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKNREWLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQEPRPTLSNTIQRSQLGPTTNLSLEMSSGQLASRQQQQQQQTELDMVPGRDGLTSYNHSQVSVQPVATTGAEHNKSLEKSDGLFAQDRDPRFSEIYPNISADQSKGISSSTVPATQQLFSQGNSFPPNPRPAENFRNSGLTPPVTIVQPSSSAGQMLAQISRHSNSTQGAAPTWTPSTRPGFSAQVPTQATAKTRSSQFGVSNFQTSSSFSAMSLPGAPTAPQGTSAYPTLTNRGSNFPSETAGQTAGQFQSRTAEGVGVWPQWQGQQPHHRSSSNEQHVQQTSAQPPSQPEVFQEMLSMLGDQSNSYNNEEFPDLTMFPPFSE", "length": 976, "header": "tr|A0A9J7HC24-1|A0A9J7HC24_CRIGR Isoform 1 of Aryl hydrocarbon receptor nuclear translocator OS=Cricetulus griseus OX=10029 GN=Arnt PE=4 SV=1 CANONICAL=A0A9J7HC24-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F627-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24/entry#A0A9J7F627-1", "sequence": { "sequence": "MYHHWVPLLLLETLDLGFKVEELLYRGLLSDDQAGLECFLLPFSRLDFDDDGEGNSKFLRCDDEQMCNDKERFARSDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNSSVDPVCMNRLSFLRNRCRNGLGSAKEGEPHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNICQPTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKNREWLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQEPRPTLSNTIQRSQLGPTTNLSLEMSSGQLASRQQQQQQQTELDMVPGRDGLTSYNHSQVSVQPVATTGAEHNKSLEKSDGLFAQDRDPRFSEIYPNISADQSKGISSSTVPATQQLFSQGNSFPPNPRPAENFRNSGLTPPVTIVQPSSSAGQMLAQISRHSNSTQGAAPTWTPSTRPGFSAQVPTQATAKTRSSQFGVSNFQTSSSFSAMSLPGAPTAPQGTSAYPTLTNRGSNFPSETAGQTAGQFQSRTAEGVGVWPQWQGQQPHHRSSSNEQHVQQTSAQPPSQPEVFQEMLSMLGDQSNSYNNEEFPDLTMFPPFSE", "length": 791, "header": "tr|A0A9J7F627-1|A0A9J7HC24_CRIGR Computationally mapped isoform of Aryl hydrocarbon receptor nuclear translocator OS=Cricetulus griseus OX=10029 GN=Arnt PE=4 SV=1 CANONICAL=A0A9J7HC24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24/entry#A0A9J7H9V2-1", "sequence": { "sequence": "MSSLPGCVSLDAATAAPDSEDMTELQQAVVEELGISMEELRQFIDEMLEKMDCIQQRKKQLAELETWSLQKESEVAYVDQLLDDASRAVINCESLVKDFYSKLGLRYHHCSSEDEASQPTEIIEIPDEDDDVLSIDSGDAGSRSPKDQLREAMAALRKSAQDVQKFMDAVNKKSSSQDLNKEMTSDVPSLGPTIASGNPGPGIQGGGAVVQRAIKRRSGLDFDDDGEGNSKFLRCDDEQMCNDKERFARSDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNSSVDPVCMNRLSFLRNRCRNGLGSAKEGEPHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNICQPTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKNREWLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQEPRPTLSNTIQRSQLGPTTNLSLEMSSGQLASRQQQQQQQTELDMVPGRDGLTSYNHSQVSVQPVATTGAEHNKSLEKSDGLFAQDRDPRFSEIYPNISADQSKGISSSTVPATQQLFSQGNSFPPNPRPAENFRNSGLTPPVTIVQPSSSAGQMLAQISRHSNSTQGAAPTWTPSTRPGFSAQVPTQATAKTRSSQFGVSNFQTSSSFSAMSLPGAPTAPQGTSAYPTLTNRGSNFPSETAGQTAGQFQSRTAEGVGVWPQWQGQQPHHRSSSNEQHVQQTSAQPPSQPEVFQEMLSMLGDQSNSYNNEEFPDLTMFPPFSE", "length": 965, "header": "tr|A0A9J7H9V2-1|A0A9J7H9V2_CRIGR Computationally mapped isoform of Aryl hydrocarbon receptor nuclear translocator OS=Cricetulus griseus OX=10029 GN=Arnt PE=4 SV=1 CANONICAL=A0A9J7HC24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24/entry#A0A9J7HAI5-1", "sequence": { "sequence": "MPVGLCEKGKSMSSLPGCVSLDAATAAPDSEDMTELQQAVVEELGISMEELRQFIDEMLEKMDCIQQRKKQLAELETWSLQKESEVAYVDQLLDDASRAVINCESLVKDFYSKLGLRYHHCSSEDEASQPTEIIEIPDEDDDVLSIDSGDAGSRSPKDQLREAMAALRKSAQDVQKFMDAVNKKSSSQDLNKEMTSDVPSLGPTIASGNPGPGIQGGGAVVQRAIKRRSGCDDEQMCNDKERFARSDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNSSVDPVCMNRLSFLRNRCRNGLGSAKEGEPHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNICQPTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKNREWLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQEPRPTLSNTIQRSQLGPTTNLSLEMSSGQLASRQQQQQQQTELDMVPGRDGLTSYNHSQVSVQPVATTGAEHNKSLEKSDGLFAQDRDPRFSEIYPNISADQSKGISSSTVPATQQLFSQGNSFPPNPRPAENFRNSGLTPPVTIVQPSSSAGQMLAQISRHSNSTQGAAPTWTPSTRPGFSAQVPTQATAKTRSSQFGVSNFQTSSSFSAMSLPGAPTAPQGTSAYPTLTNRGSNFPSETAGQTAGQFQSRTAEGVGVWPQWQGQQPHHRSSSNEQHVQQTSAQPPSQPEVFQEMLSMLGDQSNSYNNEEFPDLTMFPPFSE", "length": 961, "header": "tr|A0A9J7HAI5-1|A0A9J7HAI5_CRIGR Computationally mapped isoform of Aryl hydrocarbon receptor nuclear translocator OS=Cricetulus griseus OX=10029 GN=Arnt PE=4 SV=1 CANONICAL=A0A9J7HC24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HBT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24/entry#A0A9J7HBT2-1", "sequence": { "sequence": "MAALRKSAQDVQKFMDAVNKKSSSQDLNKEMTSDVPSLGPTIASGNPGPGIQGGGAVVQRAIKRRSGLDFDDDGEGNSKFLRCDDEQMCNDKERFARSDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNSSVDPVCMNRLSFLRNRCRNGLGSAKEGEPHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNICQPTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKNREWLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQEPRPTLSNTIQRSQLGPTTNLSLEMSSGQLASRQQQQQQQTELDMVPGRDGLTSYNHSQVSVQPVATTGAEHNKSLEKSDGLFAQDRDPRFSEIYPNISADQSKGISSSTVPATQQLFSQGNSFPPNPRPAENFRNSGLTPPVTIVQPSSSAGQMLAQISRHSNSTQGAAPTWTPSTRPGFSAQVPTQATAKTRSSQFGVSNFQTSSSFSAMSLPGAPTAPQGTSAYPTLTNRGSNFPSETAGQTAGQFQSRTAEGVGVWPQWQGQQPHHRSSSNEQHVQQTSAQPPSQPEVFQEMLSMLGDQSNSYNNEEFPDLTMFPPFSE", "length": 813, "header": "tr|A0A9J7HBT2-1|A0A9J7HBT2_CRIGR Computationally mapped isoform of Aryl hydrocarbon receptor nuclear translocator OS=Cricetulus griseus OX=10029 GN=Arnt PE=4 SV=1 CANONICAL=A0A9J7HC24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HC24-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24/entry#A0A9J7HC24-1", "sequence": { "sequence": "MPVGLCEKGKSMSSLPGCVSLDAATAAPDSEDMTELQQAVVEELGISMEELRQFIDEMLEKMDCIQQRKKQLAELETWSLQKESEVAYVDQLLDDASRAVINCESLVKDFYSKLGLRYHHCSSEDEASQPTEIIEIPDEDDDVLSIDSGDAGSRSPKDQLREAMAALRKSAQDVQKFMDAVNKKSSSQDLNKEMTSDVPSLGPTIASGNPGPGIQGGGAVVQRAIKRRSGLDFDDDGEGNSKFLRCDDEQMCNDKERFARSDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNSSVDPVCMNRLSFLRNRCRNGLGSAKEGEPHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNICQPTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKNREWLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQEPRPTLSNTIQRSQLGPTTNLSLEMSSGQLASRQQQQQQQTELDMVPGRDGLTSYNHSQVSVQPVATTGAEHNKSLEKSDGLFAQDRDPRFSEIYPNISADQSKGISSSTVPATQQLFSQGNSFPPNPRPAENFRNSGLTPPVTIVQPSSSAGQMLAQISRHSNSTQGAAPTWTPSTRPGFSAQVPTQATAKTRSSQFGVSNFQTSSSFSAMSLPGAPTAPQGTSAYPTLTNRGSNFPSETAGQTAGQFQSRTAEGVGVWPQWQGQQPHHRSSSNEQHVQQTSAQPPSQPEVFQEMLSMLGDQSNSYNNEEFPDLTMFPPFSE", "length": 976, "header": "tr|A0A9J7HC24-1|A0A9J7HC24_CRIGR Isoform 1 of Aryl hydrocarbon receptor nuclear translocator OS=Cricetulus griseus OX=10029 GN=Arnt PE=4 SV=1 CANONICAL=A0A9J7HC24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HDZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24/entry#A0A9J7HDZ1-1", "sequence": { "sequence": "MPVGLCEKGKSMSSLPGCVSLDAATAAPDSEDMTELQQAVVEELGISMEELRQFIDEMLEKMDCIQQRKKQLAELETWSLQKESEVAYVDQLLDDASRAVINCESLVKDFYSKLGLRYHHCSSEDEASQPTEIIEIPDEDDDVLSIDSGDAGSRSPKDQLREAMAALRKSAQDVQKFMDAVNKKSSSQDLNKEMTSDVPSLGPTIASGNPGPGIQGGGAVVQRAIKRRSGLDFDDDGEGNSKFLRCDDEQMCNDKERFARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNSSVDPVCMNRLSFLRNRCRNGLGSAKEGEPHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNICQPTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKNREWLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQEPRPTLSNTIQRSQLGPTTNLSLEMSSGQLASRQQQQQQQTELDMVPGRDGLTSYNHSQVSVQPVATTGAEHNKSLEKSDGLFAQDRDPRFSEIYPNISADQSKGISSSTVPATQQLFSQGNSFPPNPRPAENFRNSGLTPPVTIVQPSSSAGQMLAQISRHSNSTQGAAPTWTPSTRPGFSAQVPTQATAKTRSSQFGVSNFQTSSSFSAMSLPGAPTAPQGTSAYPTLTNRGSNFPSETAGQTAGQFQSRTAEGVGVWPQWQGQQPHHRSSSNEQHVQQTSAQPPSQPEVFQEMLSMLGDQSNSYNNEEFPDLTMFPPFSE", "length": 961, "header": "tr|A0A9J7HDZ1-1|A0A9J7HDZ1_CRIGR Computationally mapped isoform of Aryl hydrocarbon receptor nuclear translocator OS=Cricetulus griseus OX=10029 GN=Arnt PE=4 SV=1 CANONICAL=A0A9J7HC24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J837-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24/entry#A0A9J7J837-1", "sequence": { "sequence": "MAATAANPEMTSDVPSLGPTIASGNPGPGIQGGGAVVQRAIKRRSGLDFDDDGEGNSKFLRCDDEQMCNDKERFARSDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNSSVDPVCMNRLSFLRNRCRNGLGSAKEGEPHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNICQPTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKNREWLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQEPRPTLSNTIQRSQLGPTTNLSLEMSSGQLASRQQQQQQQTELDMVPGRDGLTSYNHSQVSVQPVATTGAEHNKSLEKSDGLFAQDRDPRFSEIYPNISADQSKGISSSTVPATQQLFSQGNSFPPNPRPAENFRNSGLTPPVTIVQPSSSAGQMLAQISRHSNSTQGAAPTWTPSTRPGFSAQVPTQATAKTRSSQFGVSNFQTSSSFSAMSLPGAPTAPQGTSAYPTLTNRGSNFPSETAGQTAGQFQSRTAEGVGVWPQWQGQQPHHRSSSNEQHVQQTSAQPPSQPEVFQEMLSMLGDQSNSYNNEEFPDLTMFPPFSE", "length": 792, "header": "tr|A0A9J7J837-1|A0A9J7J837_CRIGR Computationally mapped isoform of Aryl hydrocarbon receptor nuclear translocator OS=Cricetulus griseus OX=10029 GN=Arnt PE=4 SV=1 CANONICAL=A0A9J7HC24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24/entry#A0A9J7KBG7-1", "sequence": { "sequence": "MPVGLCEKGKSMSSLPGCVSLDAATAAPDSEDMTELQQAVVEELGISMEELRQFIDEMLEKMDCIQQRKKQLAELETWSLQKESEVAYVDQLLDDASRAVINCESLVKDFYSKLGLRYHHCSSEDEASQPTEIIEIPDEDDDVLSIDSGDAGSRSPKDQLREAMAALRKSAQDVQKFMDAVNKKSSSQDLNKEMTSDVPSLGPTIASGNPGPGIQGGGAVVQRAIKRRSGCDDEQMCNDKERFARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNSSVDPVCMNRLSFLRNRCRNGLGSAKEGEPHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNICQPTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKNREWLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQEPRPTLSNTIQRSQLGPTTNLSLEMSSGQLASRQQQQQQQTELDMVPGRDGLTSYNHSQVSVQPVATTGAEHNKSLEKSDGLFAQDRDPRFSEIYPNISADQSKGISSSTVPATQQLFSQGNSFPPNPRPAENFRNSGLTPPVTIVQPSSSAGQMLAQISRHSNSTQGAAPTWTPSTRPGFSAQVPTQATAKTRSSQFGVSNFQTSSSFSAMSLPGAPTAPQGTSAYPTLTNRGSNFPSETAGQTAGQFQSRTAEGVGVWPQWQGQQPHHRSSSNEQHVQQTSAQPPSQPEVFQEMLSMLGDQSNSYNNEEFPDLTMFPPFSE", "length": 946, "header": "tr|A0A9J7KBG7-1|A0A9J7HC24_CRIGR Computationally mapped isoform of Aryl hydrocarbon receptor nuclear translocator OS=Cricetulus griseus OX=10029 GN=Arnt PE=4 SV=1 CANONICAL=A0A9J7HC24-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 872, "start_aa": "Thr", "end_pos": 872, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr872", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F627", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F627" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F627", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F627" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752106", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752106", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24" } ], "pmid": "" }, { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC24" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307888", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307888" } ] }, { "annotation": "Choline transporter.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F633", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F633#function" }, { "database": "UniProtKB", "id": "RU368066", "url": "https://www.uniprot.org/uniprotkb/RU368066#function" }, { "database": "UniProtKB", "id": "A0A9J7HC55", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC55#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC55", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC55" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], 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] } ], "sequence": { "sequence": "MPLVFCQVFIMGYSVVAGAAGRLLFGYDSFGNVCGKKNSPVEGAPLSGQDMTLKKHVFFMNACDLQVKDRWLGRTALCVSRCPEKQLDTLEEIQLFADINGSSLCVYSLNSFNYTQSPNADTLCPRLPVPPSKSFPLLNRCIPQTPECYSLFASVLINDADALHRILSGIMAGRDTILGLCVFTFALSLAMLFAFRFISTLLVHIIISLVILGLLFVCGVLWWLYYDYTNDLSTELDTERENMKCMLAFAIVTTVMTAVLLVLIFTLRKRIKLTVELLQVTNKAISTCPFLLFQPLWTFAILIFFWVLWVTVLLSLGTAGTAQVIEGGQVEYKPLSGIRYMWWYHLIGLIWTSEFILACQRITIAGAMATCYFNRNQSDPPAHPILSSLSILFCYHQGTAVKGSFLITVTRIPRVILMHMYNTLREPQCGAWSRGVFRCNYCGFRCLARHLQLLNQNAYTAAAINGTDFCTSAKDAHKIMSKNTSHLMSVNCFGNFVIFLGKVLVVCFTVFGGLMAFNYNRALQVWAIPLLLVAFFAYLVAHSFLSVFETVLDILFLCFAVDLETNDGSSEKPYFMHPEFLSFITRTNNCNNARPRGHRDSLPNEEGTELRPIVR", "length": 615, "header": "tr|A0A9J7HC55-1|A0A9J7HC55_CRIGR Isoform 1 of Choline transporter-like protein OS=Cricetulus griseus OX=10029 GN=Slc44a3 PE=3 SV=1 CANONICAL=A0A9J7HC55-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F633-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC55/entry#A0A9J7F633-1", "sequence": { "sequence": "MGYSVVAGAAGRLLFGYDSFGNVCGKKNSPVEGAPLSGQDMTLKKHVFFMNACDLQVKDRWLGRTALCVSRCPEKQLDTLEEIQLFADINGSSLCVYSLNSFNYTQSPNADTLCPRLPVPPSKSFPLLNRCIPQTPECYSLFASVLINDADALHRILSGIMAGRDTILGLCVFTFALSLAMLFAFRFISTLLVHIIISLVILGLLFVCGVLWWLYYDYTNDLSTELDTERENMKCMLAFAIVTTVMTAVLLVLIFTLRKRIKLTVELLQVTNKAISTCPFLLFQPLWTFAILIFFWVLWVTVLLSLGTAGTAQVIEGGQVEYKPLSGIRYMWWYHLIGLIWTSEFILACQRITIAGAMATCYFNRNQSDPPAHPILSSLSILFCYHQGTAVKGSFLITVTRIPRVILMHMYNTLREPQCGAWSRGVFRCNYCGFRCLARHLQLLNQNAYTAAAINGTDFCTSAKDAHKIMSKNTSHLMSVNCFGNFVIFLGKVLVVCFTVFGGLMAFNYNRALQVWAIPLLLVAFFAYLVAHSFLSVFETVLDILFLCFAVDLETNDGSSEKPYFMHPEFLSFITRTNNCNNARPRGHRDSLPNEEGTELRPIVR", "length": 605, "header": "tr|A0A9J7F633-1|A0A9J7HC55_CRIGR Computationally mapped isoform of Choline transporter-like protein OS=Cricetulus griseus OX=10029 GN=Slc44a3 PE=3 SV=1 CANONICAL=A0A9J7HC55-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HC55-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC55/entry#A0A9J7HC55-1", "sequence": { "sequence": "MPLVFCQVFIMGYSVVAGAAGRLLFGYDSFGNVCGKKNSPVEGAPLSGQDMTLKKHVFFMNACDLQVKDRWLGRTALCVSRCPEKQLDTLEEIQLFADINGSSLCVYSLNSFNYTQSPNADTLCPRLPVPPSKSFPLLNRCIPQTPECYSLFASVLINDADALHRILSGIMAGRDTILGLCVFTFALSLAMLFAFRFISTLLVHIIISLVILGLLFVCGVLWWLYYDYTNDLSTELDTERENMKCMLAFAIVTTVMTAVLLVLIFTLRKRIKLTVELLQVTNKAISTCPFLLFQPLWTFAILIFFWVLWVTVLLSLGTAGTAQVIEGGQVEYKPLSGIRYMWWYHLIGLIWTSEFILACQRITIAGAMATCYFNRNQSDPPAHPILSSLSILFCYHQGTAVKGSFLITVTRIPRVILMHMYNTLREPQCGAWSRGVFRCNYCGFRCLARHLQLLNQNAYTAAAINGTDFCTSAKDAHKIMSKNTSHLMSVNCFGNFVIFLGKVLVVCFTVFGGLMAFNYNRALQVWAIPLLLVAFFAYLVAHSFLSVFETVLDILFLCFAVDLETNDGSSEKPYFMHPEFLSFITRTNNCNNARPRGHRDSLPNEEGTELRPIVR", "length": 615, "header": "tr|A0A9J7HC55-1|A0A9J7HC55_CRIGR Isoform 1 of Choline transporter-like protein OS=Cricetulus griseus OX=10029 GN=Slc44a3 PE=3 SV=1 CANONICAL=A0A9J7HC55-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F633", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F633" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F633", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F633" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774225", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774225", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "organic cation transport", "id": "GO:0015695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015695", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC55", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC55" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC55", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC55" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC55", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC55" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": 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:: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307830", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307830" } ] }, { "annotation": "Endothelial orphan receptor that acts as a key regulator of angiogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F6I7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6I7#function" }, { "database": "UniProtKB", "id": "ARBA00056160", "url": "https://www.uniprot.org/uniprotkb/ARBA00056160#function" }, { "database": "UniProtKB", "id": "A0A9J7H8Z4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Z4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", 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"MRLLLLLVGFSTLLNCSYTQNCTKTPCLPNAKCEIHNGVEACFCGVGFSGNGVTICEEADECYFSPICDNHAAGENESRGFHCFCGEGYQTSTGKSWFTPNDGSYCQDIDECSESAVCGDHAVCENVIGGFHCFCREGYQTPTGKAPFMPNDGSYCQESVNSNCHLEHDCIAANVNKTLKRIGPVQEQLAILQEIYRDSEGELSPVDIVTYIEALAQSSPVLGYMNSTASPKDDSFNSSLTEFVKIINNFVQKNTLKIWDQLPTNHRRLHLTKLMHTAELVTLRISQNFQKPTQFDLNSTDVALKVFVFDSNHMKHAHPHMNVDGGYVKIFPKKKTSYDSTGSVVVAFLCYKSIGPLLSPSDDFLLDSQNEDNSEEREKVISSVISASISSNPSTLYELEKITFTLSHGKVSDKYRTQCAFWNYSADAMSNGSWSSEGCELTYSNDTHTSCRCGHLTHFAILMSSSTSIGIKDYNILTRITQLGIIISLICLAMCIFTFWFFSEIQSTRTTIHKNLCCSLFLAELVFLVGININTNKLVCSIIAGLLHYFFLAAFAWMCIEGLHLYLVVVGIIYNKGFLHKNFYIFGYLSPAVVVGFSASLGYKYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCYENIRSCARGALALLFLLGTTWIFGVLHVAHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCCFGCLR", "length": 740, "header": "tr|A0A9J7H8Z4-1|A0A9J7H8Z4_CRIGR Isoform 1 of Adhesion G protein-coupled receptor L4 OS=Cricetulus griseus OX=10029 GN=Adgrl4 PE=3 SV=1 CANONICAL=A0A9J7H8Z4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F6I7-1", "url": 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L4 OS=Cricetulus griseus OX=10029 GN=Adgrl4 PE=3 SV=1 CANONICAL=A0A9J7H8Z4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"id": "A0A9J7H8Z4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Z4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Z4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z4" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Z4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z4" } 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"uniprot_id": "A0A9J7HBP9_CRIGR", "mass": { "chemical_mass": 328679.0, "monoisotopic_mass": 328679.0 }, "refseq": { "ac": "XP_035307793", "name": "neurobeachin isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307793" }, "gene_names": [ { "name": "Nbea", "type": "recommended", "evidence": [ { "id": "A0A9J7HBP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9" } ] }, { "name": "Nbea", "type": "synonym", "evidence": [ { "id": "XP_035307793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307793" } ] } ], "protein_names": [ { "name": "Neurobeachin", "type": "recommended", "evidence": [ { "id": "A0A9J7HBP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9/entry#names_and_taxonomy" } ] }, { "name": "Lysosomal-trafficking regulator 2", "type": "synonym", "evidence": [ { "id": "A0A9J7HBP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9/entry#names_and_taxonomy" } ] }, { "name": "neurobeachin isoform X4", "type": "synonym", "evidence": [ { "id": "XP_035307793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307793" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307793", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307793" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBP9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nbea", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9", "locus": {} } ], "crossref": [ { "id": "cd01201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06071", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06071", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770254", "url": "https://www.ncbi.nlm.nih.gov/gene/100770254", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023362", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023362", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031570", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031570", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046852", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046852", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770254", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770254", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H9M1", "url": "https://www.orthodb.org/?gene=A0A9J7H9M1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7HBP9", "url": "https://www.orthodb.org/?gene=A0A9J7HBP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13743", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13743", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13743:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13743:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02138", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02138", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06469", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06469", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14844", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14844", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20425", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20425", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20426", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20426", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307793", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307793", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MPI4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MPI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MPI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MPI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F7R6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F7R6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F7R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F7R6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9F3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9F3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9F3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9M1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9M1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBP9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J919", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J919", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J919-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J919-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K3L4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K3L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDQ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEQ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASDKPGPGLEAQPAALLAVGAGGSGGGGGAMGEPRGVAGSGSGPVVLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLVGGEFDLEMNFIIQDAESITCMTELLEHCDVTCQAEIWSMFTAILRKSVRNLQTSTEVGLIEQVLLKMSAVDDMIADLLVDMLGVLASYSITVKELKLLFSMLRGESGIWPRHAVKLLSVLNQMPQRHGPDTFFNFPGCSAAAIALPPIAKWPYQNGFTLNTWFRMDPLNNINVDKDKPYLYCFRTSKGVGYSAHFVGNCLIVTSLKSKGKGFQHCVKYDFQPRKWYMISIVHIYNRWRNSEIRCYVNGQLVSYGDMAWHVNTNDSYDKCFLGSSETADANRVFCGQLGAVYVFSEALNPAQIFAVHQLGPGYKSTFKFKSESDIHLAEHHKQVLYDGKLASSIAFSYNAKATDAQLCLESSPKENASIFVHSPHALMLQDVKAIVTHSIHSAIHSIGGIQVLFPLFAQLDNRQLNDSQVETTVCATLLAFLVELLKSSVAMQEQMLGGKGFLVIGYLLEKSSRVHITRAVLEQFLSFAKYLDGLSHGAPLLKQLCDHILFNPAIWIHTPAKVQLSLYTYLSAEFIGTATIYTTIRRVGTVLQLMHTLKYYYWVINPADSSGITPKGLDGPRPSQKEIISLRAFMLLFLKQLILKDRGVKEDELQSILNYLLTMHEDENIHDVLQLLVALMSEHPASMIPAFDQRNGIRVIYKLLASKSESIWVQALKVLGYFLKHLGHKRKVEIMHTHSLFTLLGERLMLHTNTVTVTTYNTLYEILTEQVCTQVVHKPHPEPDSTVKIQNPMILKVVATLLKNSTPSAELMEVRRLFLSDMIKLFSNSRENRRCLLQCSVWQDWMFSLGYINPKSSEEQKITEMVYNIFRILLYHAIKYEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEYQRQEEENIKKGKKGNVSTISGLSSQTTGAKGGMEIREIEDLSQSQSPESETDYPVSTDTRDLLMSTKVSDDILGSSDRPGSGVHVEVHDLLVDIKAEKVEATEVKLDDMDLSPETLVGGENGALVEVESLLDNVYSAAVEKLQNNVHGGVGIIKKNEEKDNGPLITLADEKEELPNSSTSFLFDKIPKQEEKLLPELSSNHIIPNIQDTQVHLGVGDDLGLLAHMTASVDLTCTSSIIEEKDFRIHTTSDGVNSVPERDLASSVKGLDYSEMTATTLETESSNSKIVPNIDAGSIISDTERSDDGKESGKEIRKIQTTTTTQALQGRSVTQQDRDLRVDLGFRGMPMTEEQRRQFSPGPRTTMFRIPEFKWSPMHQRLLTDLLFALETDVHVWRSHSTKSVMDFVNSNENIIFVHNTIHLISQMVDNIIIACGGILPLLSAATSPTGSKTELENIEVTQGMSAETAVTFLSRLMAMVDVLVFASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQRDRGNKSSHGSSKPQEAPQSVTATAASKTPLENVPGNLSPIKDPDRLLQDVDINRLRAVVFRDVDDSKQAQFLALAVVYFISVLMVSKYRDILEPQRETVRTGSQPGRNIRQEINSPTSTVVVIPSIPHPSLNHGLLAKLMPEQSFTHSFYKETPATFPDTVKEKETPTPGEDIQLESSVPPTDSGMGEEQVASILDGAELETAAGPDAMSELLSTLSSEVKKSHESLTEHPSEMLKPAPSISSISQTKGINVKEILKSLVAAPVEIAECGPEPIPYPDPALKREAQAILPMQFHSFDRSVVVPVKKPPPGSLSVTTVGATAAGSGLPTGSTSSIFAAPGATPKSMINTTGAVDSGSSSSSSSSSFVNGATSKNLPAVQTVAPMPEDSAENMSITAKLERALEKVAPLLREIFVDFAPFLSRTLLGSHGQELLIEGLVFCFYSKQLKSGEGLVCMKSSTSVVELVMLLCSQEWQNSIQKNAGLAFIELINEGRLLCHAMKDHIVRVANEAEFILNRQRAEDVHKHAEFESQCAQYAADRREEEKMCDHLISAAKHRDHVTANQLKQKILNILTNKHGAWGAVSHSQLHDFWRLDYWEDDLRRRRRFVRNAFGSTHAEALLKSAIEYGTEEDVVKSKKAFRSQAIVNQNSETELMLEGDDDAVSLLQEKEIDNLAGPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDAAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSALSWLVRIEPFTTFFLNANDGKFDHPDRTFSSIARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYQLGVREDAVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDLVLREAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVNRWHNTVGLRGAPGYSLDQAHHLPIEMDPLIANNSGVNKRQITDLVDQSIQINAHCFVVTADNRYILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVHTITGDLLRALEGPENCLFPRLISVSSEGHCIIYYERGRFSNFSINGKLLAQMEINDSTRAILLSSDGQNLVTGGDNGVVEVWQACDFKQLYIYPGCDAGIRAMDLSHDQRTLITGMASGSIVAFNIDFNRWHYEHQNRY", "length": 2953, "header": "tr|A0A9J7HBP9-1|A0A9J7HBP9_CRIGR Isoform 1 of Neurobeachin OS=Cricetulus griseus OX=10029 GN=Nbea PE=3 SV=1 CANONICAL=A0A9J7HBP9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MPI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9/entry#A0A8C2MPI4-1", "sequence": { "sequence": "MASDKPGPGLEAQPAALLAVGAGGSGGGGGAMGEPRGVAGSGSGPVVLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLVGGEFDLEMNFIIQDAESITCMTELLEHCDVTCQAEIWSMFTAILRKSVRNLQTSTEVGLIEQVLLKMSAVDDMIADLLVDMLGVLASYSITVKELKLLFSMLRGESGIWPRHAVKLLSVLNQMPQRHGPDTFFNFPGCSAAAIALPPIAKWPYQNGFTLNTWFRMDPLNNINVDKDKPYLYCFRTSKGVGYSAHFVGNCLIVTSLKSKGKGFQHCVKYDFQPRKWYMISIVHIYNRWRNSEIRCYVNGQLVSYGDMAWHVNTNDSYDKCFLGSSETADANRVFCGQLGAVYVFSEALNPAQIFAVHQLGPGYKSTFKFKSESDIHLAEHHKQVLYDGKLASSIAFSYNAKATDAQLCLESSPKENASIFVHSPHALMLQDVKAIVTHSIHSAIHSIGGIQVLFPLFAQLDNRQLNDSQVETTVCATLLAFLVELLKSSVAMQEQMLGGKGFLVIGYLLEKSSRVHITRAVLEQFLSFAKYLDGLSHGAPLLKQLCDHILFNPAIWIHTPAKVQLSLYTYLSAEFIGTATIYTTIRRVGTVLQLMHTLKYYYWVINPADSSGITPKGLDGPRPSQKEIISLRAFMLLFLKQLILKDRGVKEDELQSILNYLLTMHEDENIHDVLQLLVALMSEHPASMIPAFDQRNGIRVIYKLLASKSESIWVQALKVLGYFLKHLGHKRKVEIMHTHSLFTLLGERLMLHTNTVTVTTYNTLYEILTEQVCTQVVHKPHPEPDSTVKIQNPMILKVVATLLKNSTPSAELMEVRRLFLSDMIKLFSNSRENRRCLLQCSVWQDWMFSLGYINPKSSEEQKITEMVYNIFRILLYHAIKYEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEYQRQEEENIKKGKKGNVSTISGLSSQTTGAKGGMEIREIEDLSQSQSPESETDYPVSTDTRDLLMSTKVSDDILGSSDRPGSGVHVEVHDLLVDIKAEKVEATEVKLDDMDLSPETLVGGENGALVEVESLLDNVYSAAVEKLQNNVHGGVGIIKKNEEKDNGPLITLADEKEELPNSSTSFLFDKIPKQEEKLLPELSSNHIIPNIQDTQVHLGVGDDLGLLAHMTASVDLTCTSSIIEEKDFRIHTTSDGVNSVPERDLASSVKGLDYSEMTATTLETESSNSKIVPNIDAGSIISDTERSDDGKESGKEIRKIQTTTTTQALQGRSVTQQDRDLRVDLGFRGMPMTEEQRRQFSPGPRTTMFRIPEFKWSPMHQRLLTDLLFALETDVHVWRSHSTKSVMDFVNSNENIIFVHNTIHLISQMVDNIIIACGGILPLLSAATSPTGSKTELENIEVTQGMSAETAVTFLSRLMAMVDVLVFASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQRDRGNKSSHGSSKPQEAPQSVTATAASKTPLENVPGNLSPIKDPDRLLQDVDINRLRAVVFRDVDDSKQAQFLALAVVYFISVLMVSKYRDILEPQRETVRTGSQPGRNIRQEINSPTSTVVVIPSIPHPSLNHGLLAKLMPEQSFTHSFYKETPATFPDTVKEKETPTPGEDIQLESSVPPTDSGMGEEQVASILDGAELETAAGPDAMSELLSTLSSEVKKSHESLTEHPSEMLKPAPSISSISQTKGINVKEILKSLVAAPVEIAECGPEPIPYPDPALKREAQAILPMQFHSFDRSVVVPVKKPPPGSLSVTTVGATAAGSGLPTGSTSSIFAAPGATPKSMINTTGAVDSGSSSSSSSSSFVNGATSKNLPAVQTVAPMPEDSAENMSITAKLERALEKVAPLLREIFVDFAPFLSRTLLGSHGQELLIEGLVCMKSSTSVVELVMLLCSQEWQNSIQKNAGLAFIELINEGRLLCHAMKDHIVRVANEAEFILNRQRAEDVHKHAEFESQCAQYAADRREEEKMCDHLISAAKHRDHVTANQLKQKILNILTNKHGAWGAVSHSQLHDFWRLDYWEDDLRRRRRFVRNAFGSTHAEALLKSAIEYGTEEDVVKSKKAFRSQAIVNQNSETELMLEGDDDAVSLLQEKEIDNLAGPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDAAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSALSWLVRIEPFTTFFLNANDGKFDHPDRTFSSIARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYQLGVREDAVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDLVLREAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVNRWHNTVGLRGAPGYSLDQAHHLPIEMDPLIANNSGVNKRQITDLVDQSIQINAHCFVVTADNRYILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVHTITGDLLRALEGPENCLFPRLISVSSEGHCIIYYERGRFSNFSINGKLLAQMEINDSTRAILLSSDGQNLVTGGDNGVVEVWQACDFKQLYIYPGCDAGIRAMDLSHDQRTLITGMASGSIVAFNIDFNRWHYEHQNRY", "length": 2938, "header": "tr|A0A8C2MPI4-1|A0A9J7HBP9_CRIGR Computationally mapped isoform of Neurobeachin OS=Cricetulus griseus OX=10029 GN=Nbea PE=3 SV=1 CANONICAL=A0A9J7HBP9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F7R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9/entry#A0A9J7F7R6-1", "sequence": { "sequence": "MASDKPGPGLEAQPAALLAVGAGGSGGGGGAMGEPRGVAGSGSGPVVLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLVGGEFDLEMNFIIQDAESITCMTELLEHCDVTCQAEIWSMFTAILRKSVRNLQTSTEVGLIEQVLLKMSAVDDMIADLLVDMLGVLASYSITVKELKLLFSMLRGESGIWPRHAVKLLSVLNQMPQRHGPDTFFNFPGCSAAAIALPPIAKWPYQNGFTLNTWFRMDPLNNINVDKDKPYLYCFRTSKGVGYSAHFVGNCLIVTSLKSKGKGFQHCVKYDFQPRKWYMISIVHIYNRWRNSEIRCYVNGQLVSYGDMAWHVNTNDSYDKCFLGSSETADANRVFCGQLGAVYVFSEALNPAQIFAVHQLGPGYKSTFKFKSESDIHLAEHHKQVLYDGKLASSIAFSYNAKATDAQLCLESSPKENASIFVHSPHALMLQDVKAIVTHSIHSAIHSIGGIQVLFPLFAQLDNRQLNDSQVETTVCATLLAFLVELLKSSVAMQEQMLGGKGFLVIGYLLEKSSRVHITRAVLEQFLSFAKYLDGLSHGAPLLKQLCDHILFNPAIWIHTPAKVQLSLYTYLSAEFIGTATIYTTIRRVGTVLQLMHTLKYYYWVINPADSSGITPKGLDGPRPSQKEIISLRAFMLLFLKQLILKDRGVKEDELQSILNYLLTMHEDENIHDVLQLLVALMSEHPASMIPAFDQRNGIRVIYKLLASKSESIWVQALKVLGYFLKHLGHKRKVEIMHTHSLFTLLGERLMLHTNTVTVTTYNTLYEILTEQVCTQVVHKPHPEPDSTVKIQNPMILKVVATLLKNSTPSAELMEVRRLFLSDMIKLFSNSRENRRCLLQCSVWQDWMFSLGYINPKSSEEQKITEMVYNIFRILLYHAIKYEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEYQRQEEENIKKGKKGNVSTISGLSSQTTGAKGGMEIREIEDLSQSQSPESETDYPVSTDTRDLLMSTKVSDDILGSSDRPGSGVHVEVHDLLVDIKAEKVEATEVKLDDMDLSPETLVGGENGALVEVESLLDNVYSAAVEKLQNNVHGGVGIIKKNEEKDNGPLITLADEKEELPNSSTSFLFDKIPKQEEKLLPELSSNHIIPNIQDTQVHLGVGDDLGLLAHMTASVDLTCTSSIIEEKDFRIHTTSDGVNSVPERDLASSVKGLDYSEMTATTLETESSNSKIVPNIDAGSIISDTERSDDGKESGKEIRKIQTTTTTQALQGRSVTQQDRDLRVDLGFRGMPMTEEQRRQFSPGPRTTMFRIPEFKWSPMHQRLLTDLLFALETDVHVWRSHSTKSVMDFVNSNENIIFVHNTIHLISQMVDNIIIACGGILPLLSAATSPTTELENIEVTQGMSAETAVTFLSRLMAMVDVLVFASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQRDRGNKSSHGSSKPQEAPQSVTATAASKTPLENVPGNLSPIKDPDRLLQDVDINRLRAVVFRDVDDSKQAQFLALAVVYFISVLMVSKYRDILEPQRETVRTGSQPGRNIRQEINSPTSTVVVIPSIPHPSLNHGLLAKLMPEQSFTHSFYKETPATFPDTVKEKETPTPGEDIQLESSVPPTDSGMGEEQVASILDGAELETAAGPDAMSELLSTLSSEVKKSHESLTEHPSEMLKPAPSISSISQTKGINVKEILKSLVAAPVEIAECGPEPIPYPDPALKREAQAILPMQFHSFDRSVVVPVKKPPPGSLSVTTVGATAAGSGLPTGSTSSIFAAPGATPKSMINTTGAVDSGSSSSSSSSSFVNGATSKNLPAVQTVAPMPEDSAENMSITAKLERALEKVAPLLREIFVDFAPFLSRTLLGSHGQELLIEGLVCMKSSTSVVELVMLLCSQEWQNSIQKNAGLAFIELINEGRLLCHAMKDHIVRVANEAEFILNRQRAEDVHKHAEFESQCAQYAADRREEEKMCDHLISAAKHRDHVTANQLKQKILNILTNKHGAWGAVSHSQLHDFWRLDYWEDDLRRRRRFVRNAFGSTHAEALLKSAIEYGTEEDVVKSKKAFRSQAIVNQNSETELMLEGDDDAVSLLQEKEIDNLAGPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDAAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSALSWLVRIEPFTTFFLNANDGKFDHPDRTFSSIARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYQLGVREDAVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDLVLREAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVNRWHNTVGLRGAPGYSLDQAHHLPIEMDPLIANNSGVNKRQITDLVDQSIQINAHCFVVTADNRYILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVHTITGDLLRALEGPENCLFPRLISVSSEGHCIIYYERGRFSNFSINGKLLAQMEINDSTRAILLSSDGQNLVTGGDNGVVEVWQACDFKQLYIYPGCDAGIRAMDLSHDQRTLITGMASGSIVAFNIDFNRWHYEHQNRY", "length": 2935, "header": "tr|A0A9J7F7R6-1|A0A9J7HBP9_CRIGR Computationally mapped isoform of Neurobeachin OS=Cricetulus griseus OX=10029 GN=Nbea PE=3 SV=1 CANONICAL=A0A9J7HBP9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9/entry#A0A9J7H9F3-1", "sequence": { "sequence": "MASDKPGPGLEAQPAALLAVGAGGSGGGGGAMGEPRGVAGSGSGPVVLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLVGGEFDLEMNFIIQDAESITCMTELLEHCDVTCQAEIWSMFTAILRKSVRNLQTSTEVGLIEQVLLKMSAVDDMIADLLVDMLGVLASYSITVKELKLLFSMLRGESGIWPRHAVKLLSVLNQMPQRHGPDTFFNFPGCSAAAIALPPIAKWPYQNGFTLNTWFRMDPLNNINVDKDKPYLYCFRTSKGVGYSAHFVGNCLIVTSLKSKGKGFQHCVKYDFQPRKWYMISIVHIYNRWRNSEIRCYVNGQLVSYGDMAWHVNTNDSYDKCFLGSSETADANRVFCGQLGAVYVFSEALNPAQIFAVHQLGPGYKSTFKFKSESDIHLAEHHKQVLYDGKLASSIAFSYNAKATDAQLCLESSPKENASIFVHSPHALMLQDVKAIVTHSIHSAIHSIGGIQVLFPLFAQLDNRQLNDSQVETTVCATLLAFLVELLKSSVAMQEQMLGGKGFLVIGYLLEKSSRVHITRAVLEQFLSFAKYLDGLSHGAPLLKQLCDHILFNPAIWIHTPAKVQLSLYTYLSAEFIGTATIYTTIRRVGTVLQLMHTLKYYYWVINPADSSGITPKGLDGPRPSQKEIISLRAFMLLFLKQLILKDRGVKEDELQSILNYLLTMHEDENIHDVLQLLVALMSEHPASMIPAFDQRNGIRVIYKLLASKSESIWVQALKVLGYFLKHLGHKRKVEIMHTHSLFTLLGERLMLHTNTVTVTTYNTLYEILTEQVCTQVVHKPHPEPDSTVKIQNPMILKVVATLLKNSTPSAELMEVRRLFLSDMIKLFSNSRENRRCLLQCSVWQDWMFSLGYINPKSSEEQKITEMVYNIFRILLYHAIKYEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEYQRQEEENIKKGKKGNVSTISGLSSQTTGAKGGMEIREIEDLSQSQSPESETDYPVSTDTRDLLMSTKVSDDILGSSDRPGSGVHVEVHDLLVDIKAEKVEATEVKLDDMDLSPETLVGGENGALVEVESLLDNVYSAAVEKLQNNVHGGVGIIKKNEEKDNGPLITLADEKEELPNSSTSFLFDKIPKQEEKLLPELSSNHIIPNIQDTQVHLGVGDDLGLLAHMTASVDLTCTSSIIEEKDFRIHTTSDGVNSVPERDLASSVKGLDYSEMTATTLETESSNSKIVPNIDAGSIISDTERSDDGKESGKEIRKIQTTTTTQALQGRSVTQQDRDLRVDLGFRGMPMTEEQRRQFSPGPRTTMFRIPEFKWSPMHQRLLTDLLFALETDVHVWRSHSTKSVMDFVNSNENIIFVHNTIHLISQMVDNIIIACGGILPLLSAATSPTGSKTELENIEVTQGMSAETAVTFLSRLMAMVDVLVFASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQRDRGNKSSHGSSKPQEAPQSVTATAASKTPLENVPGNLSPIKDPDRLLQDVDINRLRAVVFRDVDDSKQAQFLALAVVYFISVLMVSKYRDILEPQRETVRTGSQPGRNIRQEINSPTSTVVVIPSIPHPSLNHGLLAKLMPEQSFTHSFYKETPATFPDTVKEKETPTPGEDIQLESSVPPTDSGMGEEQVASILDGAELETAAGPDAMSELLSTLSSEVKKSHESLTEHPSEMLKPAPSISSISQTKGINVKEILKSLVAAPVEIAECGPEPIPYPDPALKREAQAILPMQFHSFDRSVVVPVKKPPPGSLSVTTVGATAAGSGLPTGSTSSIFAAPGATPKSMINTTGAVDSGSSSSSSSSSFVNGATSKNLPAVQTVAPMPEDSAENMSITAKLERALEKVAPLLREIFVDFAPFLSRTLLGSHGQELLIEGLVFCFYSKQLKSGEGLVCMKSSTSVVELVMLLCSQEWQNSIQKNAGLAFIELINEGRLLCHAMKDHIVRVANEAEFILNRQRAEDVHKHAEFESQCAQYAADRREEEKMCDHLISAAKHRDHVTANQLKQKILNILTNKHGAWGAVSHSQLHDFWRLDYWEDDLRRRRRFVRNAFGSTHAEALLKSAIEYGTEEDVVKSKKAFRSQAIVNQNSETELMLEGDDDAVSLLQEKEIDNLAGPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDAAFKKIDTKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSALSWLVRIEPFTTFFLNANDGKFDHPDRTFSSIARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYQLGVREDAVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDLVLREAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVNRWHNTVGLRGAPGYSLDQAHHLPIEMDPLIANNSGVNKRQITDLVDQSIQINAHCFVVTADNRYILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVHTITGDLLRALEGPENCLFPRLISVSSEGHCIIYYERGRFSNFSINGKLLAQMEINDSTRAILLSSDGQNLVTGGDNGVVEVWQACDFKQLYIYPGCDAGIRAMDLSHDQRTLITGMASGSIVAFNIDFNRWHYEHQNRY", "length": 2803, "header": "tr|A0A9J7H9F3-1|A0A9J7H9F3_CRIGR Computationally mapped isoform of Neurobeachin isoform X11 OS=Cricetulus griseus OX=10029 GN=Nbea PE=4 SV=1 CANONICAL=A0A9J7HBP9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9/entry#A0A9J7H9M1-1", "sequence": { "sequence": "MKSSTSVVELVMLLCSQEWQNSIQKNAGLAFIELINEGRLLCHAMKDHIVRVANEAEFILNRQRAEDVHKHAEFESQCAQYAADRREEEKMCDHLISAAKHRDHVTANQLKQKILNILTNKHGAWGAVSHSQLHDFWRLDYWEDDLRRRRRFVRNAFGSTHAEALLKSAIEYGTEEDVVKSKKAFRSQAIVNQNSETELMLEGDDDAVSLLQEKEIDNLAGPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDAAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSALSWLVRIEPFTTFFLNANDGKFDHPDRTFSSIARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYQLGVREDAVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDLVLREAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVNRWHNTVGLRGAPGYSLDQAHHLPIEMDPLIANNSGVNKRQITDLVDQSIQINAHCFVVTADNRYILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVHTITGDLLRALEGPENCLFPRLISVSSEGHCIIYYERGRFSNFSINGKLLAQMEINDSTRAILLSSDGQNLVTGGDNGVVEVWQACDFKQLYIYPGCDAGIRAMDLSHDQRTLITGMASGSIVAFNIDFNRWHYEHQNRY", "length": 1017, "header": "tr|A0A9J7H9M1-1|A0A9J7H9M1_CRIGR Computationally mapped isoform of Neurobeachin OS=Cricetulus griseus OX=10029 GN=Nbea PE=4 SV=1 CANONICAL=A0A9J7HBP9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HBP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9/entry#A0A9J7HBP9-1", "sequence": { "sequence": "MASDKPGPGLEAQPAALLAVGAGGSGGGGGAMGEPRGVAGSGSGPVVLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLVGGEFDLEMNFIIQDAESITCMTELLEHCDVTCQAEIWSMFTAILRKSVRNLQTSTEVGLIEQVLLKMSAVDDMIADLLVDMLGVLASYSITVKELKLLFSMLRGESGIWPRHAVKLLSVLNQMPQRHGPDTFFNFPGCSAAAIALPPIAKWPYQNGFTLNTWFRMDPLNNINVDKDKPYLYCFRTSKGVGYSAHFVGNCLIVTSLKSKGKGFQHCVKYDFQPRKWYMISIVHIYNRWRNSEIRCYVNGQLVSYGDMAWHVNTNDSYDKCFLGSSETADANRVFCGQLGAVYVFSEALNPAQIFAVHQLGPGYKSTFKFKSESDIHLAEHHKQVLYDGKLASSIAFSYNAKATDAQLCLESSPKENASIFVHSPHALMLQDVKAIVTHSIHSAIHSIGGIQVLFPLFAQLDNRQLNDSQVETTVCATLLAFLVELLKSSVAMQEQMLGGKGFLVIGYLLEKSSRVHITRAVLEQFLSFAKYLDGLSHGAPLLKQLCDHILFNPAIWIHTPAKVQLSLYTYLSAEFIGTATIYTTIRRVGTVLQLMHTLKYYYWVINPADSSGITPKGLDGPRPSQKEIISLRAFMLLFLKQLILKDRGVKEDELQSILNYLLTMHEDENIHDVLQLLVALMSEHPASMIPAFDQRNGIRVIYKLLASKSESIWVQALKVLGYFLKHLGHKRKVEIMHTHSLFTLLGERLMLHTNTVTVTTYNTLYEILTEQVCTQVVHKPHPEPDSTVKIQNPMILKVVATLLKNSTPSAELMEVRRLFLSDMIKLFSNSRENRRCLLQCSVWQDWMFSLGYINPKSSEEQKITEMVYNIFRILLYHAIKYEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEYQRQEEENIKKGKKGNVSTISGLSSQTTGAKGGMEIREIEDLSQSQSPESETDYPVSTDTRDLLMSTKVSDDILGSSDRPGSGVHVEVHDLLVDIKAEKVEATEVKLDDMDLSPETLVGGENGALVEVESLLDNVYSAAVEKLQNNVHGGVGIIKKNEEKDNGPLITLADEKEELPNSSTSFLFDKIPKQEEKLLPELSSNHIIPNIQDTQVHLGVGDDLGLLAHMTASVDLTCTSSIIEEKDFRIHTTSDGVNSVPERDLASSVKGLDYSEMTATTLETESSNSKIVPNIDAGSIISDTERSDDGKESGKEIRKIQTTTTTQALQGRSVTQQDRDLRVDLGFRGMPMTEEQRRQFSPGPRTTMFRIPEFKWSPMHQRLLTDLLFALETDVHVWRSHSTKSVMDFVNSNENIIFVHNTIHLISQMVDNIIIACGGILPLLSAATSPTGSKTELENIEVTQGMSAETAVTFLSRLMAMVDVLVFASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQRDRGNKSSHGSSKPQEAPQSVTATAASKTPLENVPGNLSPIKDPDRLLQDVDINRLRAVVFRDVDDSKQAQFLALAVVYFISVLMVSKYRDILEPQRETVRTGSQPGRNIRQEINSPTSTVVVIPSIPHPSLNHGLLAKLMPEQSFTHSFYKETPATFPDTVKEKETPTPGEDIQLESSVPPTDSGMGEEQVASILDGAELETAAGPDAMSELLSTLSSEVKKSHESLTEHPSEMLKPAPSISSISQTKGINVKEILKSLVAAPVEIAECGPEPIPYPDPALKREAQAILPMQFHSFDRSVVVPVKKPPPGSLSVTTVGATAAGSGLPTGSTSSIFAAPGATPKSMINTTGAVDSGSSSSSSSSSFVNGATSKNLPAVQTVAPMPEDSAENMSITAKLERALEKVAPLLREIFVDFAPFLSRTLLGSHGQELLIEGLVFCFYSKQLKSGEGLVCMKSSTSVVELVMLLCSQEWQNSIQKNAGLAFIELINEGRLLCHAMKDHIVRVANEAEFILNRQRAEDVHKHAEFESQCAQYAADRREEEKMCDHLISAAKHRDHVTANQLKQKILNILTNKHGAWGAVSHSQLHDFWRLDYWEDDLRRRRRFVRNAFGSTHAEALLKSAIEYGTEEDVVKSKKAFRSQAIVNQNSETELMLEGDDDAVSLLQEKEIDNLAGPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDAAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSALSWLVRIEPFTTFFLNANDGKFDHPDRTFSSIARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYQLGVREDAVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDLVLREAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVNRWHNTVGLRGAPGYSLDQAHHLPIEMDPLIANNSGVNKRQITDLVDQSIQINAHCFVVTADNRYILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVHTITGDLLRALEGPENCLFPRLISVSSEGHCIIYYERGRFSNFSINGKLLAQMEINDSTRAILLSSDGQNLVTGGDNGVVEVWQACDFKQLYIYPGCDAGIRAMDLSHDQRTLITGMASGSIVAFNIDFNRWHYEHQNRY", "length": 2953, "header": "tr|A0A9J7HBP9-1|A0A9J7HBP9_CRIGR Isoform 1 of Neurobeachin OS=Cricetulus griseus OX=10029 GN=Nbea PE=3 SV=1 CANONICAL=A0A9J7HBP9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J919-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9/entry#A0A9J7J919-1", "sequence": { "sequence": "MASDKPGPGLEAQPAALLAVGAGGSGGGGGAMGEPRGVAGSGSGPVVLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLVGGEFDLEMNFIIQDAESITCMTELLEHCDVTCQAEIWSMFTAILRKSVRNLQTSTEVGLIEQVLLKMSAVDDMIADLLVDMLGVLASYSITVKELKLLFSMLRGESGIWPRHAVKLLSVLNQMPQRHGPDTFFNFPGCSAAAIALPPIAKWPYQNGFTLNTWFRMDPLNNINVDKDKPYLYCFRTSKGVGYSAHFVGNCLIVTSLKSKGKGFQHCVKYDFQPRKWYMISIVHIYNRWRNSEIRCYVNGQLVSYGDMAWHVNTNDSYDKCFLGSSETADANRVFCGQLGAVYVFSEALNPAQIFAVHQLGPGYKSTFKFKSESDIHLAEHHKQVLYDGKLASSIAFSYNAKATDAQLCLESSPKENASIFVHSPHALMLQDVKAIVTHSIHSAIHSIGGIQVLFPLFAQLDNRQLNDSQVETTVCATLLAFLVELLKSSVAMQEQMLGGKGFLVIGYLLEKSSRVHITRAVLEQFLSFAKYLDGLSHGAPLLKQLCDHILFNPAIWIHTPAKVQLSLYTYLSAEFIGTATIYTTIRRVGTVLQLMHTLKYYYWVINPADSSGITPKGLDGPRPSQKEIISLRAFMLLFLKQLILKDRGVKEDELQSILNYLLTMHEDENIHDVLQLLVALMSEHPASMIPAFDQRNGIRVIYKLLASKSESIWVQALKVLGYFLKHLGHKRKVEIMHTHSLFTLLGERLMLHTNTVTVTTYNTLYEILTEQVCTQVVHKPHPEPDSTVKIQNPMILKVVATLLKNSTPSAELMEVRRLFLSDMIKLFSNSRENRRCLLQCSVWQDWMFSLGYINPKSSEEQKITEMVYNIFRILLYHAIKYEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEYQRQEEENIKKGKKGNVSTISGLSSQTTGAKGGMEIREIEDLSQSQSPESETDYPVSTDTRDLLMSTKVSDDILGSSDRPGSGVHVEVHDLLVDIKAEKVEATEVKLDDMDLSPETLVGGENGALVEVESLLDNVYSAAVEKLQNNVHGGVGIIKKNEEKDNGPLITLADEKEELPNSSTSFLFDKIPKQEEKLLPELSSNHIIPNIQDTQVHLGVGDDLGLLAHMTASVDLTCTSSIIEEKDFRIHTTSDGVNSVPERDLASSVKGLDYSEMTATTLETESSNSKIVPNIDAGSIISDTERSDDGKESGKEIRKIQTTTTTQALQGRSVTQQDRDLRVDLGFRGMPMTEEQRRQFSPGPRTTMFRIPEFKWSPMHQRLLTDLLFALETDVHVWRSHSTKSVMDFVNSNENIIFVHNTIHLISQMVDNIIIACGGILPLLSAATSPTGSKTELENIEVTQGMSAETAVTFLSRLMAMVDVLVFASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQRDRGNKSSHGSSKPQEAPQSVTATAASKTPLENVPGNLSPIKDPDRLLQDVDINRLRAVVFRDVDDSKQAQFLALAVVYFISVLMVSKYRDILEPQRETVRTGSQPGRNIRQEINSPTSTVVVIPSIPHPSLNHGLLAKLMPEQSFTHSFYKETPATFPDTVKEKETPTPGEDIQLESSVPPTDSGMGEEQVASILDGAELETAAGPDAMSELLSTLSSEVKKSHESLTEHPSEMLKPAPSISSISQTKGINVKEILKSLVAAPVEIAECGPEPIPYPDPALKREAQAILPMQFHSFDRSVVVPVKKPPPGSLSVTTVGATAAGSGLPTGSTSSIFAAPGATPKSMINTTGAVDSGSSSSSSSSSFVNGATSKNLPAVQTVAPMPEDSAENMSITAKLERALEKVAPLLREIFVDFAPFLSRTLLGSHGQELLIEGLVCMKSSTSVVELVMLLCSQEWQNSIQKNAGLAFIELINEGRLLCHAMKDHIVRVANEAEFILNRQRAEDVHKHAEFESQCAQYAADRREEEKMCDHLISAAKHRDHVTANQLKQKILNILTNKHGAWGAVSHSQLHDFWRLDYWEDDLRRRRRFVRNAFGSTHAEALLKSAIEYGTEEDVVKSKKAFRSQAIVNQNSETELMLEGDDDAVSLLQEKEIDNLAGPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDAAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSALSWLVRIEPFTTFFLNANDGKFDHPDRTFSSIARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYQLGVREDAVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDLVLREAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVNRWHNTVGLRGAPGYSLDQAHHLPIEMDPLIANNSGVNKRQITDLVDQSIQINAHCFVVTADNRYILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVHTITGDLLRALEGPENCLFPRLISVSSEGHCIIYYERGRFSNFSINGKLLAQMEINDSTRAILLSSDGQNLVTGGDNGVVEVWQACDFKQLYIYPGCDAGIRAMDLSHDQRTLITGMASGSIVAFNIDFNRWHYEHQNRY", "length": 2933, "header": "tr|A0A9J7J919-1|A0A9J7J919_CRIGR Computationally mapped isoform of Neurobeachin OS=Cricetulus griseus OX=10029 GN=Nbea PE=3 SV=1 CANONICAL=A0A9J7HBP9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K3L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9/entry#A0A9J7K3L4-1", "sequence": { "sequence": "MASDKPGPGLEAQPAALLAVGAGGSGGGGGAMGEPRGVAGSGSGPVVLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLVGGEFDLEMNFIIQDAESITCMTELLEHCDVTCQAEIWSMFTAILRKSVRNLQTSTEVGLIEQVLLKMSAVDDMIADLLVDMLGVLASYSITVKELKLLFSMLRGESGIWPRHAVKLLSVLNQMPQRHGPDTFFNFPGCSAAAIALPPIAKWPYQNGFTLNTWFRMDPLNNINVDKDKPYLYCFRTSKGVGYSAHFVGNCLIVTSLKSKGKGFQHCVKYDFQPRKWYMISIVHIYNRWRNSEIRCYVNGQLVSYGDMAWHVNTNDSYDKCFLGSSETADANRVFCGQLGAVYVFSEALNPAQIFAVHQLGPGYKSTFKFKSESDIHLAEHHKQVLYDGKLASSIAFSYNAKATDAQLCLESSPKENASIFVHSPHALMLQDVKAIVTHSIHSAIHSIGGIQVLFPLFAQLDNRQLNDSQVETTVCATLLAFLVELLKSSVAMQEQMLGGKGFLVIGYLLEKSSRVHITRAVLEQFLSFAKYLDGLSHGAPLLKQLCDHILFNPAIWIHTPAKVQLSLYTYLSAEFIGTATIYTTIRRVGTVLQLMHTLKYYYWVINPADSSGITPKGLDGPRPSQKEIISLRAFMLLFLKQLILKDRGVKEDELQSILNYLLTMHEDENIHDVLQLLVALMSEHPASMIPAFDQRNGIRVIYKLLASKSESIWVQALKVLGYFLKHLGHKRKVEIMHTHSLFTLLGERLMLHTNTVTVTTYNTLYEILTEQVCTQVVHKPHPEPDSTVKIQNPMILKVVATLLKNSTPSAELMEVRRLFLSDMIKLFSNSRENRRCLLQCSVWQDWMFSLGYINPKSSEEQKITEMVYNIFRILLYHAIKYEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEYQRQEEENIKKGKKGNVSTISGLSSQTTGAKGGMEIREIEDLSQSQSPESETDYPVSTDTRDLLMSTKVSDDILGSSDRPGSGVHVEVHDLLVDIKAEKVEATEVKLDDMDLSPETLVGGENGALVEVESLLDNVYSAAVEKLQNNVHGGVGIIKKNEEKDNGPLITLADEKEELPNSSTSFLFDKIPKQEEKLLPELSSNHIIPNIQDTQVHLGVGDDLGLLAHMTASVDLTCTSSIIEEKDFRIHTTSDGVNSVPERDLASSVKGLDYSEMTATTLETESSNSKIVPNIDAGSIISDTERSDDGKESGKEIRKIQTTTTTQALQGRSVTQQDRDLRVDLGFRGMPMTEEQRRQFSPGPRTTMFRIPEFKWSPMHQRLLTDLLFALETDVHVWRSHSTKSVMDFVNSNENIIFVHNTIHLISQMVDNIIIACGGILPLLSAATSPTTELENIEVTQGMSAETAVTFLSRLMAMVDVLVFASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQRDRGNKSSHGSSKPQEAPQSVTATAASKTPLENVPGNLSPIKDPDRLLQDVDINRLRAVVFRDVDDSKQAQFLALAVVYFISVLMVSKYRDILEPQRETVRTGSQPGRNIRQEINSPTSTVVVIPSIPHPSLNHGLLAKLMPEQSFTHSFYKETPATFPDTVKEKETPTPGEDIQLESSVPPTDSGMGEEQVASILDGAELETAAGPDAMSELLSTLSSEVKKSHESLTEHPSEMLKPAPSISSISQTKGINVKEILKSLVAAPVEIAECGPEPIPYPDPALKREAQAILPMQFHSFDRSVVVPVKKPPPGSLSVTTVGATAAGSGLPTGSTSSIFAAPGATPKSMINTTGAVDSGSSSSSSSSSFVNGATSKNLPAVQTVAPMPEDSAENMSITAKLERALEKVAPLLREIFVDFAPFLSRTLLGSHGQELLIEGLVFCFYSKQLKSGEGLVCMKSSTSVVELVMLLCSQEWQNSIQKNAGLAFIELINEGRLLCHAMKDHIVRVANEAEFILNRQRAEDVHKHAEFESQCAQYAADRREEEKMCDHLISAAKHRDHVTANQLKQKILNILTNKHGAWGAVSHSQLHDFWRLDYWEDDLRRRRRFVRNAFGSTHAEALLKSAIEYGTEEDVVKSKKAFRSQAIVNQNSETELMLEGDDDAVSLLQEKEIDNLAGPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDAAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSALSWLVRIEPFTTFFLNANDGKFDHPDRTFSSIARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYQLGVREDAVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDLVLREAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVNRWHNTVGLRGAPGYSLDQAHHLPIEMDPLIANNSGVNKRQITDLVDQSIQINAHCFVVTADNRYILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVHTITGDLLRALEGPENCLFPRLISVSSEGHCIIYYERGRFSNFSINGKLLAQMEINDSTRAILLSSDGQNLVTGGDNGVVEVWQACDFKQLYIYPGCDAGIRAMDLSHDQRTLITGMASGSIVAFNIDFNRWHYEHQNRY", "length": 2950, "header": "tr|A0A9J7K3L4-1|A0A9J7HBP9_CRIGR Computationally mapped isoform of Neurobeachin OS=Cricetulus griseus OX=10029 GN=Nbea PE=3 SV=1 CANONICAL=A0A9J7HBP9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KDQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9/entry#A0A9J7KDQ6-1", "sequence": { "sequence": "MASDKPGPGLEAQPAALLAVGAGGSGGGGGAMGEPRGVAGSGSGPVVLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLVGGEFDLEMNFIIQDAESITCMTELLEHCDVTCQAEIWSMFTAILRKSVRNLQTSTEVGLIEQVLLKMSAVDDMIADLLVDMLGVLASYSITVKELKLLFSMLRGESGIWPRHAVKLLSVLNQMPQRHGPDTFFNFPGCSAAAIALPPIAKWPYQNGFTLNTWFRMDPLNNINVDKDKPYLYCFRTSKGVGYSAHFVGNCLIVTSLKSKGKGFQHCVKYDFQPRKWYMISIVHIYNRWRNSEIRCYVNGQLVSYGDMAWHVNTNDSYDKCFLGSSETADANRVFCGQLGAVYVFSEALNPAQIFAVHQLGPGYKSTFKFKSESDIHLAEHHKQVLYDGKLASSIAFSYNAKATDAQLCLESSPKENASIFVHSPHALMLQDVKAIVTHSIHSAIHSIGGIQVLFPLFAQLDNRQLNDSQVETTVCATLLAFLVELLKSSVAMQEQMLGGKGFLVIGYLLEKSSRVHITRAVLEQFLSFAKYLDGLSHGAPLLKQLCDHILFNPAIWIHTPAKVQLSLYTYLSAEFIGTATIYTTIRRVGTVLQLMHTLKYYYWVINPADSSGITPKGLDGPRPSQKEIISLRAFMLLFLKQLILKDRGVKEDELQSILNYLLTMHEDENIHDVLQLLVALMSEHPASMIPAFDQRNGIRVIYKLLASKSESIWVQALKVLGYFLKHLGHKRKVEIMHTHSLFTLLGERLMLHTNTVTVTTYNTLYEILTEQVCTQVVHKPHPEPDSTVKIQNPMILKVVATLLKNSTPSAELMEVRRLFLSDMIKLFSNSRENRRCLLQCSVWQDWMFSLGYINPKSSEEQKITEMVYNIFRILLYHAIKYEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEYQRQEEENIKKGKKGNVSTISGLSSQTTGAKGGMEIREIEDLSQSQSPESETDYPVSTDTRDLLMSTKVSDDILGSSDRPGSGVHVEVHDLLVDIKAEKVEATEVKLDDMDLSPETLVGGENGALVEVESLLDNVYSAAVEKLQNNVHGGVGIIKKNEEKDNGPLITLADEKEELPNSSTSFLFDKIPKQEEKLLPELSSNHIIPNIQDTQVHLGVGDDLGLLAHMTASVDLTCTSSIIEEKDFRIHTTSDGVNSVPERDLASSVKGLDYSEMTATTLETESSNSKIVPNIDAGSIISDTERSDDGKESGKEIRKIQTTTTTQALQGRSVTQQDRDLRVDLGFRGMPMTEEQRRQFSPGPRTTMFRIPEFKWSPMHQRLLTDLLFALETDVHVWRSHSTKSVMDFVNSNENIIFVHNTIHLISQMVDNIIIACGGILPLLSAATSPTGSKTELENIEVTQGMSAETAVTFLSRLMAMVDVLVFASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQRDRGNKSSHGSSKPQEAPQSVTATAASKTPLENVPGNLSPIKDPDRLLQDVDINRLRAVVFRDVDDSKQAQFLALAVVYFISVLMVSKYRDILEPQRETVRTGSQPGRNIRQEINSPTSTVVVIPSIPHPSLNHGLLAKLMPEQSFTHSFYKETPATFPDTVKEKETPTPGEDIQLESSVPPTDSGMGEEQVASILDGAELETAAGPDAMSELLSTLSSEVKKSHESLTEHPSEMLKPAPSISSISQTKGINVKEILKSLVAAPVEIAECGPEPIPYPDPALKREAQAILPMQFHSFDRSVVVPVKKPPPGSLSVTTVGATAAGSGLPTGSTSSIFAAPGATPKSAVDSGSSSSSSSSSFVNGATSKNLPAVQTVAPMPEDSAENMSITAKLERALEKVAPLLREIFVDFAPFLSRTLLGSHGQELLIEGLVFCFYSKQLKSGEGLVCMKSSTSVVELVMLLCSQEWQNSIQKNAGLAFIELINEGRLLCHAMKDHIVRVANEAEFILNRQRAEDVHKHAEFESQCAQYAADRREEEKMCDHLISAAKHRDHVTANQLKQKILNILTNKHGAWGAVSHSQLHDFWRLDYWEDDLRRRRRFVRNAFGSTHAEALLKSAIEYGTEEDVVKSKKAFRSQAIVNQNSETELMLEGDDDAVSLLQEKEIDNLAGPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDAAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSALSWLVRIEPFTTFFLNANDGKFDHPDRTFSSIARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYQLGVREDAVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDLVLREAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVNRWHNTVGLRGAPGYSLDQAHHLPIEMDPLIANNSGVNKRQITDLVDQSIQINAHCFVVTADNRYILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVHTITGDLLRALEGPENCLFPRLISVSSEGHCIIYYERGRFSNFSINGKLLAQMEINDSTRAILLSSDGQNLVTGGDNGVVEVWQACDFKQLYIYPGCDAGIRAMDLSHDQRTLITGMASGSIVAFNIDFNRWHYEHQNRY", "length": 2947, "header": "tr|A0A9J7KDQ6-1|A0A9J7HBP9_CRIGR Computationally mapped isoform of Neurobeachin OS=Cricetulus griseus OX=10029 GN=Nbea PE=3 SV=1 CANONICAL=A0A9J7HBP9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KEQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9/entry#A0A9J7KEQ3-1", "sequence": { "sequence": "MASDKPGPGLEAQPAALLAVGAGGSGGGGGAMGEPRGVAGSGSGPVVLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLVGGEFDLEMNFIIQDAESITCMTELLEHCDVTCQAEIWSMFTAILRKSVRNLQTSTEVGLIEQVLLKMSAVDDMIADLLVDMLGVLASYSITVKELKLLFSMLRGESGIWPRHAVKLLSVLNQMPQRHGPDTFFNFPGCSAAAIALPPIAKWPYQNGFTLNTWFRMDPLNNINVDKDKPYLYCFRTSKGVGYSAHFVGNCLIVTSLKSKGKGFQHCVKYDFQPRKWYMISIVHIYNRWRNSEIRCYVNGQLVSYGDMAWHVNTNDSYDKCFLGSSETADANRVFCGQLGAVYVFSEALNPAQIFAVHQLGPGYKSTFKFKSESDIHLAEHHKQVLYDGKLASSIAFSYNAKATDAQLCLESSPKENASIFVHSPHALMLQDVKAIVTHSIHSAIHSIGGIQVLFPLFAQLDNRQLNDSQVETTVCATLLAFLVELLKSSVAMQEQMLGGKGFLVIGYLLEKSSRVHITRAVLEQFLSFAKYLDGLSHGAPLLKQLCDHILFNPAIWIHTPAKVQLSLYTYLSAEFIGTATIYTTIRRVGTVLQLMHTLKYYYWVINPADSSGITPKGLDGPRPSQKEIISLRAFMLLFLKQLILKDRGVKEDELQSILNYLLTMHEDENIHDVLQLLVALMSEHPASMIPAFDQRNGIRVIYKLLASKSESIWVQALKVLGYFLKHLGHKRKVEIMHTHSLFTLLGERLMLHTNTVTVTTYNTLYEILTEQVCTQVVHKPHPEPDSTVKIQNPMILKVVATLLKNSTPSAELMEVRRLFLSDMIKLFSNSRENRRCLLQCSVWQDWMFSLGYINPKSSEEQKITEMVYNIFRILLYHAIKYEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEYQRQEEENIKKGKKGNVSTISGLSSQTTGAKGGMEIREIEDLSQSQSPESETDYPVSTDTRDLLMSTKVSDDILGSSDRPGSGVHVEVHDLLVDIKAEKVEATEVKLDDMDLSPETLVGGENGALVEVESLLDNVYSAAVEKLQNNVHGGVGIIKKNEEKDNGPLITLADEKEELPNSSTSFLFDKIPKQEEKLLPELSSNHIIPNIQDTQVHLGVGDDLGLLAHMTASVDLTCTSSIIEEKDFRIHTTSDGVNSVPERDLASSVKGLDYSEMTATTLETESSNSKIVPNIDAGSIISDTERSDDGKESGKEIRKIQTTTTTQALQGRSVTQQDRDLRVDLGFRGMPMTEEQRRQFSPGPRTTMFRIPEFKWSPMHQRLLTDLLFALETDVHVWRSHSTKSVMDFVNSNENIIFVHNTIHLISQMVDNIIIACGGILPLLSAATSPTGSKTELENIEVTQGMSAETAVTFLSRLMAMVDVLVFASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQRDRGNKSSHGSSKPQEAPQSVTATAASKTPLENVPGNLSPIKDPDRLLQDVDINRLRAVVFRDVDDSKQAQFLALAVVYFISVLMVSKYRDILEPQRETVRTGSQPGRNIRQEINSPTSTVVVIPSIPHPSLNHGLLAKLMPEQSFTHSFYKETPATFPDTVKEKETPTPGEDIQLESSVPPTDSGMGEEQVASILDGAELETAAGPDAMSELLSTLSSEVKKSHESLTEHPSEMLKPAPSISSISQTKGINVKEILKSLVAAPVEIAECGPEPIPYPDPALKREAQAILPMQFHSFDRSVVVPVKKPPPGSLSVTTVGATAAGSGLPTGSTSSIFAAPGATPKSMINTTGAVDSGSSSSSSSSSFVNGATSKNLPAVQTVAPMPEDSAENMSITAKLERALEKVAPLLREIFVDFAPFLSRTLLGSHGQELLIEGLVFCFYSKQLKSGEGLVCMKSSTSVVELVMLLCSQEWQNSIQKNAGLAFIELINEGRLLCHAMKDHIVRVANEAEFILNRQRAEDVHKHAEFESQCAQYAADRREEEKMCDHLISAAKHRDHVTANQLKQKILNILTNKHGAWGAVSHSQLHDFWRLDYWEDDLRRRRRFVRNAFGSTHAEALLKSAIEYGTEEDVVKSKKAFRSQAIVNQNSETELMLEGDDDAVSLLQEKEIDNLAGPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDAAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSALSWLVRIEPFTTFFLNANDGKFDHPDRTFSSIARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYQLGVREDAVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDLVLREAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVNRWHNTVGLRGAPGYSLDQAHHLPIEMDPLIANNSGVNKRQITDLVDQSIQINAHCFVVTADNRYILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVHTITGDLLRALEGPENCLFPRLISVSSEGHCIIYYERGRFSNFSINGKLLAQMEINDSTRAILLSSDGQNLVTGGDNGVVEVWQACDFKQLYIYPGCDAGIRAMDLSHDQRTLITGMASGSIVAFNIDFNRWHYEHQNRY", "length": 2948, "header": "tr|A0A9J7KEQ3-1|A0A9J7HBP9_CRIGR Computationally mapped isoform of Neurobeachin OS=Cricetulus griseus OX=10029 GN=Nbea PE=3 SV=1 CANONICAL=A0A9J7HBP9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1651, "start_aa": "Thr", "end_pos": 1651, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1651", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F7R6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F7R6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F7R6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F7R6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770254", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770254", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBP9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBP9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBP9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBP9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBP9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HAL9-1", "uniprot_ac": "A0A9J7HAL9", "uniprot_id": "A0A9J7HAL9_CRIGR", "mass": { "chemical_mass": 56316.0, "monoisotopic_mass": 56316.0 }, "refseq": { "ac": "XP_035306479", "name": "BLOC-1-related complex subunit 8 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306479" }, "gene_names": [ { "name": "Borcs8", "type": "recommended", "evidence": [ { "id": "A0A9J7HAL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAL9" } ] }, { "name": "Borcs8", "type": "synonym", "evidence": [ { "id": "XP_035306479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306479" } ] } ], "protein_names": [ { "name": "BLOC-1-related complex subunit 8 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_035306479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306479" }, { "id": "A0A9J7HAL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAL9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306479" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAL9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAL9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Borcs8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAL9", "locus": {} } ], "crossref": [ { "id": "A0A9J7HAL9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HAL9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00265", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00265", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770611", "url": "https://www.ncbi.nlm.nih.gov/gene/100770611", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770611", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770611", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7F822", "url": "https://www.orthodb.org/?gene=A0A9J7F822", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7HAL9", "url": "https://www.orthodb.org/?gene=A0A9J7HAL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11945", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11945", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11945:SF383", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11945:SF383", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21146", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21146", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21146:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21146:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00319", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00319", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10167", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10167", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306479", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7F822", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F822", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F822-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F822-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F887", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F887", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F887-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F887-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F8X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F8X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8X6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7N7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7N7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9S6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAL9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBR7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JCA5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JCA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JCA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JCA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEPEMQLKGKKVTDKFTESVYVLANEPSVALYRLQEHVRRSLPELAQHKCCEESGGQQCVLPQCGRPAQTGHQYPRPHEHQRPGPQPGETGLTLTPEDSWGHQLPTQNSHSRQPGTMGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKYTEYSEPHESRTNADILQTLKRRGVGLDGPEPEVEEEPEGPGEKSLRTAGGDRGSASPLPLIYVRELRPPNTVNTEFEMETQRAPVAPAMSVSELSHRVPLAPPGCEPGGPGEAASVHSRPPHFRPPGLGHPIFSPSHLTGKTPPPLYLATDGRRPDLPAGLVGARGGLGTSVRGGWRRTERKGGGRWSPPASVSSPCCPSRGACTAACRAPAPRAPLWGALPSCPRVPQPALPADCTPADAAPLPLQPAPWPLTRDALDPGRPGLCEEGPPSRVASPPTPPISIKSERLSPATGASGDFPRSFPYPLLLARPLAEPLRPAASLRRLTPDGWPR", "length": 519, "header": "tr|A0A9J7HAL9-1|A0A9J7HAL9_CRIGR Isoform 1 of BLOC-1-related complex subunit 8 isoform X4 OS=Cricetulus griseus OX=10029 GN=Borcs8 PE=4 SV=1 CANONICAL=A0A9J7HAL9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F822-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAL9/entry#A0A9J7F822-1", "sequence": { "sequence": "MEEPEMQLKGKKVTDKFTESVYVLANEPSVALYRLQEHVRRSLPELAQHKADMQRWEEQSQGAIYTVEYACSAVKSLVDSSVYFRSVEGLLKQAISIRDHMNTSAQGHR", "length": 109, "header": "tr|A0A9J7F822-1|A0A9J7HAL9_CRIGR Computationally mapped isoform of BLOC-1-related complex subunit 8 isoform X4 OS=Cricetulus griseus OX=10029 GN=Borcs8 PE=4 SV=1 CANONICAL=A0A9J7HAL9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F887-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAL9/entry#A0A9J7F887-1", "sequence": { "sequence": "MEEPEMQLKGKKVTDKFTESVYVLANEPSVALYRLQEHVRRSLPELAQHKCCEESGGQQCVLPQCGRPAQTGHQYPRPHEHQRPGPQPGETGLTLTPEDSWGHQLPTQNSHSRQPGTMGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKYTEYSEPHESRTNADILQTLKRRGVGLDGPEPEVEEEPEGPGEKSLRTAGGDRGSASPLPLIYPVAPAMSVSELSHRVPLAPPGCEPGGPGEAASVHSRPPHFRPPGLGHPIFSPSHLTGKTPPPLYLATDGRRPDLPAGLVGARGGLGTSRSLYSGLQSPGAPGPALGSFAFLPPGSADCTPADAAPLPLQPAPWPLTRDALDPGRPGLCEEGPPSRVASPPTPPISIKSERLSPATGASGDFPRSFPYPLLLARPLAEPLRPAASLRRLTPDGWPR", "length": 463, "header": "tr|A0A9J7F887-1|A0A9J7HAL9_CRIGR Computationally mapped isoform of BLOC-1-related complex subunit 8 isoform X4 OS=Cricetulus griseus OX=10029 GN=Borcs8 PE=4 SV=1 CANONICAL=A0A9J7HAL9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F8X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAL9/entry#A0A9J7F8X6-1", "sequence": { "sequence": "MEEPEMQLKGKKVTDKFTESVYVLANEPSVALYRLQEHVRRSLPELAQHKCCEESGGQQCVLPQCGRPAQTGHQYPRPHEHQRPGPQPGETGLTLTPEDSWGHQLPTQNSHSRQPGTMGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKYTEYSEPHESRTNADILQTLKRRGVGLDGPEPEVEEEPEGPGEKSLRTAGGDRGSASPLPLIYVRELRPPNTVNTEFEMETQRAPVAPAMSVSELSHRVPLAPPGCEPGGPGEAASVHSRPPHFRPPGLGHPIFSPSHLTGKTPPPLYLATDGRRPDLPAGLVGARGGLGTSQRSLYSGLQSPGAPGPALGSFAFLPPGSADCTPADAAPLPLQPAPWPLTRDALDPGRPGLCEEGPPSRVASPPTPPISIKSERLSPATGASGDFPRSFPYPLLLARPLAEPLRPAASLRRLTPDGWPR", "length": 485, "header": "tr|A0A9J7F8X6-1|A0A9J7HAL9_CRIGR Computationally mapped isoform of BLOC-1-related complex subunit 8 isoform X4 OS=Cricetulus griseus OX=10029 GN=Borcs8 PE=4 SV=1 CANONICAL=A0A9J7HAL9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAL9/entry#A0A9J7H7N7-1", "sequence": { "sequence": "MEEPEMQLKGKKVTDKFTESVYVLANEPSVALYRLQEHVRRSLPELAQHKCCEESGGQQCVLPQCGRPAQTGHQYPRPHEHQRPGPQPGETGLTLTPEDSWGHQLPTQNSHSRQPGTMGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKYTEYSEPHESRTNADILQTLKRRGVGLDGPEPEVEEEPEGPGEKSLRTAGGDRGSASPLPLIYVRELRPPNTVNTEFEMETQRAPVAPAMSVSELSHRVPLAPPGCEPGGPGEAASVHSRPPHFRPPGLGHPIFSPSHLTGKTPPPLYLATDGRRPDLPAGLVGARGGLGTSQRSLYSGLQSPGAPGPALGSFAFLPPGSAASSPGRLHPRRRRSAPPTARALAPDAGRAGPGPARPV", "length": 423, "header": "tr|A0A9J7H7N7-1|A0A9J7H7N7_CRIGR Computationally mapped isoform of BLOC-1-related complex subunit 8 isoform X9 OS=Cricetulus griseus OX=10029 GN=Borcs8 PE=4 SV=1 CANONICAL=A0A9J7HAL9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAL9/entry#A0A9J7H9S6-1", "sequence": { "sequence": "MEEPEMQLKGKKVTDKFTESVYVLANEPSVALYRLQEHVRRSLPELAQHKCCEESGGQQCVLPQCGRPAQTGHQYPRPHEHQRPGPQPGETGLTLTPEDSWGHQLPTQNSHSRQPGTMGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKYTEYSEPHESRTNADILQTLKRRGVGLDGPEPEVEEEPEGPGEKSLRTAGGDRGSASPLPLIYPVAPAMSVSELSHRVPLAPPGCEPGGPGEAASVHSRPPHFRPPGLGHPIFSPSHLTGKTPPPLYLATDGRRPDLPAGLVGARGGLGTSVRGGWRRTERKGGGRWSPPASVSSPCCPSRGACTAACRAPAPRAPLWGALPSCPRVPQPALPADCTPADAAPLPLQPAPWPLTRDALDPGRPGLCEEGPPSRVASPPTPPISIKSERLSPATGASGDFPRSFPYPLLLARPLAEPLRPAASLRRLTPDGWPR", "length": 498, "header": "tr|A0A9J7H9S6-1|A0A9J7H9S6_CRIGR Computationally mapped isoform of BLOC-1-related complex subunit 8 isoform X5 OS=Cricetulus griseus OX=10029 GN=Borcs8 PE=4 SV=1 CANONICAL=A0A9J7HAL9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAL9/entry#A0A9J7HAL9-1", "sequence": { "sequence": "MEEPEMQLKGKKVTDKFTESVYVLANEPSVALYRLQEHVRRSLPELAQHKCCEESGGQQCVLPQCGRPAQTGHQYPRPHEHQRPGPQPGETGLTLTPEDSWGHQLPTQNSHSRQPGTMGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKYTEYSEPHESRTNADILQTLKRRGVGLDGPEPEVEEEPEGPGEKSLRTAGGDRGSASPLPLIYVRELRPPNTVNTEFEMETQRAPVAPAMSVSELSHRVPLAPPGCEPGGPGEAASVHSRPPHFRPPGLGHPIFSPSHLTGKTPPPLYLATDGRRPDLPAGLVGARGGLGTSVRGGWRRTERKGGGRWSPPASVSSPCCPSRGACTAACRAPAPRAPLWGALPSCPRVPQPALPADCTPADAAPLPLQPAPWPLTRDALDPGRPGLCEEGPPSRVASPPTPPISIKSERLSPATGASGDFPRSFPYPLLLARPLAEPLRPAASLRRLTPDGWPR", "length": 519, "header": "tr|A0A9J7HAL9-1|A0A9J7HAL9_CRIGR Isoform 1 of BLOC-1-related complex subunit 8 isoform X4 OS=Cricetulus griseus OX=10029 GN=Borcs8 PE=4 SV=1 CANONICAL=A0A9J7HAL9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HBR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAL9/entry#A0A9J7HBR7-1", "sequence": { "sequence": "MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKYTEYSEPHESRTNADILQTLKRRGVGLDGPEPEVEEEPEGPGEKSLRTAGGDRGSASPLPLIYVRELRPPNTVNTEFEMETQRAPVAPAMSVSELSHRVPLAPPGCEPGGPGEAASVHSRPPHFRPPGLGHPIFSPSHLTGKTPPPLYLATDGRRPDLPAGLVGARGGLGTSVRGGWRRTERKGGGRWSPPASVSSPCCPSRGACTAACRAPAPRAPLWGALPSCPRVPQPALPADCTPADAAPLPLQPAPWPLTRDALDPGRPGLCEEGPPSRVASPPTPPISIKSERLSPATGASGDFPRSFPYPLLLARPLAEPLRPAASLRRLTPDGWPR", "length": 402, "header": "tr|A0A9J7HBR7-1|A0A9J7HBR7_CRIGR Computationally mapped isoform of BLOC-1-related complex subunit 8 isoform X10 OS=Cricetulus griseus OX=10029 GN=Borcs8 PE=4 SV=1 CANONICAL=A0A9J7HAL9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JCA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAL9/entry#A0A9J7JCA5-1", "sequence": { "sequence": "MEEPEMQLKGKKVTDKFTESVYVLANEPSVALYRLQEHVRRSLPELAQHKCCEESGGQQCVLPQCGRPAQTGHQYPRPHEHQRPGPQPGETGLTLTPEDSWGHQLPTQNSHSRQPGTMGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKYTEYSEPHESRTNADILQTLKRRGVGLDGPEPEVEEEPEGPGEKSLRTAGGDRGSASPLPLIYVRELRPPNTVNTEFEMETQRAPVAPAMSVSELSHRVPLAPPGCEPGGPGEAASVHSRPPHFRPPGLGHPIFSPSHLTGKTPPPLYLATDGRRPDLPAGLVGARGGLGTSRSLYSGLQSPGAPGPALGSFAFLPPGSADCTPADAAPLPLQPAPWPLTRDALDPGRPGLCEEGPPSRVASPPTPPISIKSERLSPATGASGDFPRSFPYPLLLARPLAEPLRPAASLRRLTPDGWPR", "length": 484, "header": "tr|A0A9J7JCA5-1|A0A9J7JCA5_CRIGR Computationally mapped isoform of BLOC-1-related complex subunit 8 isoform X7 OS=Cricetulus griseus OX=10029 GN=Borcs8 PE=4 SV=1 CANONICAL=A0A9J7HAL9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 465, "start_aa": "Thr", "end_pos": 465, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr465", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F887", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F887" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F887", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F887" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770611", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770611", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAL9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAL9" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAL9", "url": 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. 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"MEPREAPGKENMGSKRKNLTFLRPRLYMLERRKTDTVVDGSVSGDHSGTLRRSQSDRTEYNQKLQEKMTPQTERSSAVTPTPEEEQQMGRMMAKRAKIIRELIQTERDYVTDLELCVREVVQPLRNKQVDRLDVDSLFSNMESVHQISAKLLSLLEEATTDVEPAMQVIGEVFLQIKGPLEDIYKVYCYHHDEAHSILESYEKEEELRQHLGHCIQSLKNIYMQEGKPNLLDMGSLMIKPIQRVMKYPLLLCELRNSTPPSHPDYRALEEAFTAVKDINVNINELKRRKDLVLKYKKNDEDESLKDKLSKLNIHSISKKSKRVTNHLKILTRGESQVKDNTFNREEKLFRSLEKTLRLCVKNISSCLQHIEDVMPFTLQSVAELHEISHKDGEKNFGEPQSHASNPCQDFVARSQRLILTPLSALLSLFPGPQKLIQKRYDKLLDYNSSLPRSAADESDLAKKEYEALNAQLVEELQAFNQAARKILLNCLCSFITLLRDLMLMALEAYSTVKLVPLLVLSISEIQNRVLEEVQNLNFVKDNSSTFIERKLSFEKKKPAQILPEAPHQTDDHRSKLLSTYRAEEIYRAKRKCNATQEHDINLLEGELVAVLEQKDPLGSTSRWFVDTGFVKGYVYSSFLKPYNPAKEQTADAENTFCDDDFENLSLFVSCRPAGDSVRDTPEDSISDSSSSLSGTGGKFETNGADVDNFQEVDEQVFYAVHAFQARSDHELSLQEYQRVHILRFCDLSGNKEWWLAEAQGQKGYVPANYLGKMTYA", "length": 776, "header": "tr|A0A9J7HBW7-1|A0A9J7HBW7_CRIGR Isoform 1 of Rho guanine nucleotide exchange factor 38 OS=Cricetulus griseus OX=10029 GN=LOC100755633 PE=4 SV=1 CANONICAL=A0A9J7HBW7-1" }, "isoforms": [ { 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"glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 79, "start_aa": "Thr", "end_pos": 79, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr79", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 81, "start_aa": "Thr", "end_pos": 81, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr81", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F8M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8M3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F8M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8M3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755633", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755633", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBW7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBW7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBW7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBW7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 542, "end_pos": 544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 593, "end_pos": 595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 663, "end_pos": 665, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": 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"ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 581, "end_pos": 644, "start_aa": "Arg", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 79, 81 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 447, "end_pos": 449 }, { "start_pos": 542, "end_pos": 544 }, { "start_pos": 593, "end_pos": 595 }, { "start_pos": 663, "end_pos": 665 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613631.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016836083", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836083" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Z1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mrtfb", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z1", "locus": {} } ], "crossref": [ { "id": "100771346", "url": "https://www.ncbi.nlm.nih.gov/gene/100771346", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043451", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043451", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771346", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771346", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LTT9", "url": "https://www.orthodb.org/?gene=A0A8C2LTT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G9X9", "url": "https://www.orthodb.org/?gene=A0A9J7G9X9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H5Z1", "url": "https://www.orthodb.org/?gene=A0A9J7H5Z1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22793", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22793", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22793:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22793:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02755", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02755", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016836083", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836083", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LTT9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LTT9-1", "url": 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"MALMSLQQATSERCLILPVVSGWNMMDHTGAIDTEEELGPLAHLAPSPQSEAVAHEFQELSLQSSQHLPPLNERKNVLQLRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIGVAKEDYPHTHGEFSFDEDSSDALSPDQPASQESQGSAASPSEPKVSASPPPVTANTPAQFTSVSPAVPEFLKTPLTSDQPPTRSTAPILSTNTVSSAKSAPTLVKQSHPKNPNDKHRSKKCKDPKPRVKKLKYHQYIPPNQKGEKSEPQMDSNYARLLQQQQLFLQLQILSQQQQQQQQQHYNYQTILPAPIKNDKNSSSSTPVPTRRPGPLPSSLDDLKVSELKTELKLRGLPVSGTKPDLIERLKPYQEVASSGLAAGSIVAVSSAAIVTSNPEVTVALPVTTLHNAVTSSVSTFKADLPPAGPSNVAHVESAHSPLPISPSPSEPSSLSTDDTNMTDTFTEIMSMMSPSQFLCASPLRVAGHEDSLSPTSTLSALELDAAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRGQRPPDPQPSGPSQPLSTSDQTHGSAGSSIKDEASLPDCSSPQQPISTGSQTLVAKKAVVIKQEVPIAQAEQQSVVSQFYVSPQGQPPALVAQPQALLATQTTQLLLPVSIQGSNVTSVQLPVGSLQLQTPAPGGAQAQPQIATATQIPAATLAPTLPQKQEAFPQHVLGQPQPIRKVFTNSAPNTVLQYQRPPGPTTQQPFVSKSSNPVLQSRSTPLAPLQNGPSPASKPSSPSPPQQFVVQHSLFGTPVTKTKDPPRYEEAIKQTRSAQPALPEVSNVHSQQMDDLFDILIKSGEISFPIKEEPSPISKMRPVTANITTMPVNTVVSRPPPQVQIAPPVSLEPMNSLSASLENQLEAFLDGTLPSTNDVAPLQSSSEDREPFSLIEDLQNDLLSHSSMLYHSHSPMETSEAQFVAGTPCLSLDLSDSNLDNMEWLDITMPTTSSGLTPLSATAPSMFSADFLDPQDLPLPWD", "length": 1093, "header": "tr|A0A9J7H5Z1-1|A0A9J7H5Z1_CRIGR Isoform 1 of Myocardin-related transcription factor B isoform X1 OS=Cricetulus griseus OX=10029 GN=Mrtfb PE=4 SV=1 CANONICAL=A0A9J7H5Z1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LTT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z1/entry#A0A8C2LTT9-1", "sequence": { "sequence": 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"length": 1057, "header": "tr|A0A8C2LTT9-1|A0A9J7H5Z1_CRIGR Computationally mapped isoform of Myocardin-related transcription factor B isoform X1 OS=Cricetulus griseus OX=10029 GN=Mrtfb PE=4 SV=1 CANONICAL=A0A9J7H5Z1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9X9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z1/entry#A0A9J7G9X9-1", "sequence": { "sequence": "MPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIGVAKEDYPHTHGEFSFDEDSSDALSPDQPASQESQGSAASPSEPKVSASPPPVTANTPAQFTSVSPAVPEFLKTPLTSDQPPTRSTAPILSTNTVSSAKSAPTLVKQSHPKNPNDKHRSKKCKDPKPRVKKLKYHQYIPPNQKGEKSEPQMDSNYARLLQQQQLFLQLQILSQQQQQQQQQHYNYQTILPAPIKNDKNSSSSTPVPTRRPGPLPSSLDDLKVSELKTELKLRGLPVSGTKPDLIERLKPYQEVASSGLAAGSIVAVSSAAIVTSNPEVTVALPVTTLHNAVTSSVSTFKADLPPAGPSNVAHVESAHSPLPISPSPSEPSSLSTDDTNMTDTFTEIMSMMSPSQFLCASPLRVAGHEDSLSPTSTLSALELDAAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRGQRPPDPQPSGPSQPLSTSDQTHGSAGSSIKDEASLPDCSSPQQPISTGSQTLVAKKAVVIKQEVPIAQAEQQSVVSQFYVSPQGQPPALVAQPQALLATQTTQLLLPVSIQGSNVTSVQLPVGSLQLQTPAPGGAQAQPQIATATQIPAATLAPTLPQKQEAFPQHVLGQPQPIRKVFTNSAPNTVLQYQRPPGPTTQQPFVSKSSNPVLQSRSTPLAPLQNGPSPASKPSSPSPPQQFVVQHSLFGTPVTKTKDPPRYEEAIKQTRSAQPALPEVSNVHSQQMDDLFDILIKSGEISFPIKEEPSPISKMRPVTANITTMPVNTVVSRPPPQVQIAPPVSLEPMNSLSASLENQLEAFLDGTLPSTNDVAPLQSSSEDREPFSLIEDLQNDLLSHSSMLYHSHSPMETSEAQFVAGTPCLSLDLSDSNLDNMEWLDITMPTTSSGLTPLSATAPSMFSADFLDPQDLPLPWD", "length": 997, "header": "tr|A0A9J7G9X9-1|A0A9J7H5Z1_CRIGR Computationally mapped isoform of Myocardin-related transcription factor B isoform X1 OS=Cricetulus griseus OX=10029 GN=Mrtfb PE=4 SV=1 CANONICAL=A0A9J7H5Z1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H5Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z1/entry#A0A9J7H5Z1-1", "sequence": { "sequence": "MALMSLQQATSERCLILPVVSGWNMMDHTGAIDTEEELGPLAHLAPSPQSEAVAHEFQELSLQSSQHLPPLNERKNVLQLRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIGVAKEDYPHTHGEFSFDEDSSDALSPDQPASQESQGSAASPSEPKVSASPPPVTANTPAQFTSVSPAVPEFLKTPLTSDQPPTRSTAPILSTNTVSSAKSAPTLVKQSHPKNPNDKHRSKKCKDPKPRVKKLKYHQYIPPNQKGEKSEPQMDSNYARLLQQQQLFLQLQILSQQQQQQQQQHYNYQTILPAPIKNDKNSSSSTPVPTRRPGPLPSSLDDLKVSELKTELKLRGLPVSGTKPDLIERLKPYQEVASSGLAAGSIVAVSSAAIVTSNPEVTVALPVTTLHNAVTSSVSTFKADLPPAGPSNVAHVESAHSPLPISPSPSEPSSLSTDDTNMTDTFTEIMSMMSPSQFLCASPLRVAGHEDSLSPTSTLSALELDAAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRGQRPPDPQPSGPSQPLSTSDQTHGSAGSSIKDEASLPDCSSPQQPISTGSQTLVAKKAVVIKQEVPIAQAEQQSVVSQFYVSPQGQPPALVAQPQALLATQTTQLLLPVSIQGSNVTSVQLPVGSLQLQTPAPGGAQAQPQIATATQIPAATLAPTLPQKQEAFPQHVLGQPQPIRKVFTNSAPNTVLQYQRPPGPTTQQPFVSKSSNPVLQSRSTPLAPLQNGPSPASKPSSPSPPQQFVVQHSLFGTPVTKTKDPPRYEEAIKQTRSAQPALPEVSNVHSQQMDDLFDILIKSGEISFPIKEEPSPISKMRPVTANITTMPVNTVVSRPPPQVQIAPPVSLEPMNSLSASLENQLEAFLDGTLPSTNDVAPLQSSSEDREPFSLIEDLQNDLLSHSSMLYHSHSPMETSEAQFVAGTPCLSLDLSDSNLDNMEWLDITMPTTSSGLTPLSATAPSMFSADFLDPQDLPLPWD", "length": 1093, "header": "tr|A0A9J7H5Z1-1|A0A9J7H5Z1_CRIGR Isoform 1 of Myocardin-related transcription factor B isoform X1 OS=Cricetulus griseus OX=10029 GN=Mrtfb PE=4 SV=1 CANONICAL=A0A9J7H5Z1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 816, "start_aa": "Thr", "end_pos": 816, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr816", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9X9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9X9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9X9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9X9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771346", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771346", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Z1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Z1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Z1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Z1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z1" } ], "pmid": "" }, { "name": "smooth muscle cell differentiation", "id": "GO:0051145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051145", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Z1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 937, "end_pos": 939, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H5Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z1" }, { "id": "PS50800", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAP", "eco_id": "ECO_0000259", "start_pos": 413, "end_pos": 447, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 816 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 394, "end_pos": 396 }, { "start_pos": 534, "end_pos": 536 }, { "start_pos": 734, "end_pos": 736 }, { "start_pos": 937, "end_pos": 939 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": 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"table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H5N6-1", "uniprot_ac": "A0A9J7H5N6", "uniprot_id": "A0A9J7H5N6_CRIGR", "mass": { "chemical_mass": 64748.0, "monoisotopic_mass": 64748.0 }, "refseq": { "ac": "XP_035303590", "name": "epsin-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303590" }, "gene_names": [ { "name": "Epn2", "type": "recommended", "evidence": [ { "id": "A0A9J7H5N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6" } ] }, { "name": "Epn2", "type": "synonym", "evidence": [ { "id": "XP_035303590", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303590" } ] } ], "protein_names": [ { "name": "Epsin-2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7H5N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6/entry#names_and_taxonomy" } ] }, { "name": "epsin-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035303590", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303590" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303590", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303590" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Epn2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6", "locus": {} } ], "crossref": [ { "id": "cd16990", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16990", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774824", "url": "https://www.ncbi.nlm.nih.gov/gene/100774824", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013809", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013809", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774824", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774824", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H5N6", "url": "https://www.orthodb.org/?gene=A0A9J7H5N6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12276", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12276", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12276:SF50", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12276:SF50", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01417", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01417", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303590", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303590", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LL96", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LL96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LL96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LL96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4W5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4W5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4W5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5N6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDDERLKAERVQALKTKERMAQVATGVGSNQITFGRGSSQPNLSTSYSEQEYGKAGGSPASYHGSTSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQSSESVQTARGSKEERLRRGDDLRLQMALEESRRDTVKVPKKKEVKTCCKPGSHSQQTTLLDLMDALPSSCPVTQKTEPWGPGTSANQTNPWGGTAAPVNISNPWPSFGTKPAASVDPWGVPTTASTQSVPKNPDPWAASQQPASNAGKTADAWGAAKPSSASGSFELFSNFNGTVKDDFSEFDNLRASKKPAESGASVPPQDSRTTSPDLFESQPLTSASSKPSSARKTPESFLGPNAALVNLDSLVTKPAPPAQSLNPFLAPGAATSTPVNPFQVNQPQPLTLNQLRGSPVLGSSASFGSGPGMEPVAPVTSVAPPSALGASGSSLTPLGPTAMNMIVQARSRSACWGPVILLQKMRALLTEAPPY", "length": 603, "header": "tr|A0A9J7H5N6-1|A0A9J7H5N6_CRIGR Isoform 1 of Epsin-2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Epn2 PE=3 SV=1 CANONICAL=A0A9J7H5N6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LL96-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6/entry#A0A8C2LL96-1", "sequence": { "sequence": "MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDDERLKAERVQALKTKERMAQVATGVGSNQITFGRGSSQPNLSTSYSEQEYGKAGGSPASYHGSTSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQSSESVQTARGSKEERLRRGDDLRLQMALEESRRDTVKVPKKKEVKTCCKPGSHSQQTTLLDLMDALPSSCPVTQKTEPWGPGTSANQTNPWGGTAAPVNISNPWPSFGTKPAASVDPWGVPTTASTQSVPKNPDPWAASQQPASNAGKTADAWGAAKPSSASGSFELFSNFNGTVKDDFSEFDNLRASKKPAESGASVPPQDSRTTSPDLFESQPLTSASSKPSSARKTPESFLGPNAALVNLDSLVTKPAPPAQSLNPFLAPGAATSTPVNPFQVNQPQPLTLNQLRGSPVLGSSASFGSGPGMEPVAPVTSVAPPSALGASGSSLTPLGPTAMNMVGSVGIPPSAAQATGTTNPFLL", "length": 595, "header": "tr|A0A8C2LL96-1|A0A8C2LL96_CRIGR Computationally mapped isoform of Epsin-2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Epn2 PE=3 SV=1 CANONICAL=A0A9J7H5N6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GDY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6/entry#A0A9J7GDY0-1", "sequence": { "sequence": "MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDDERLKAERVQALKTKERMAQVATGVGSNQITFGRGSSQPNLSTSYSEQEYGKAGGSPASYHGSTSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQEERLRRGDDLRLQMALEESRRDTVKVPKKKEVKTCCKPGSHSQQTTLLDLMDALPSSCPVTQKTEPWGPGTSANQTNPWGGTAAPVNISNPWPSFGTKPAASVDPWGVPTTASTQSVPKNPDPWAASQQPASNAGKTADAWGAAKPSSASGSFELFSNFNGTVKDDFSEFDNLRASKKPAESGASVPPQDSRTTSPDLFESQPLTSASSKPSSARKTPESFLGPNAALVNLDSLVTKPAPPAQSLNPFLAPGAATSTPVNPFQVNQPQPLTLNQLRGSPVLGSSASFGSGPGMEPVAPVTSVAPPSALGASGSSLTPLGPTAMNMVGSVGIPPSAAQATGTTNPFLL", "length": 583, "header": "tr|A0A9J7GDY0-1|A0A9J7H5N6_CRIGR Computationally mapped isoform of Epsin-2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Epn2 PE=3 SV=1 CANONICAL=A0A9J7H5N6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H4W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6/entry#A0A9J7H4W5-1", "sequence": { "sequence": "MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDDERLKAERVQALKTKERMAQVATGVGSNQITFGRGSSQPNLSTSYSEQEYGKAGGSPASYHGSTSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQEERLRRGDDLRLQMALEESRRDTVKVPKKKEVKTCCKPGSHSQQTTLLDLMDALPSSCPVTQKTEPWGPGTSANQTNPWGGTAAPVNISNPWPSFGTKPAASVDPWGVPTTASTQSVPKNPDPWAASQQPASNAGKTADAWGAAKPSSASGSFELFSNFNGTVKDDFSEFDNLRASKKPAESGASVPPQDSRTTSPDLFESQPLTSASSKPSSARKTPESFLGPNAALVNLDSLVTKPAPPAQSLNPFLAPGAATSTPVNPFQVNQPQPLTLNQLRGSPVLGSSASFGSGPGMEPVAPVTSVAPPSALGASGSSLTPLGPTAMNMIVQARSRSACWGPVILLQKMRALLTEAPPY", "length": 591, "header": "tr|A0A9J7H4W5-1|A0A9J7H5N6_CRIGR Computationally mapped isoform of Epsin-2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Epn2 PE=3 SV=1 CANONICAL=A0A9J7H5N6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H5N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6/entry#A0A9J7H5N6-1", "sequence": { "sequence": "MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDDERLKAERVQALKTKERMAQVATGVGSNQITFGRGSSQPNLSTSYSEQEYGKAGGSPASYHGSTSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQSSESVQTARGSKEERLRRGDDLRLQMALEESRRDTVKVPKKKEVKTCCKPGSHSQQTTLLDLMDALPSSCPVTQKTEPWGPGTSANQTNPWGGTAAPVNISNPWPSFGTKPAASVDPWGVPTTASTQSVPKNPDPWAASQQPASNAGKTADAWGAAKPSSASGSFELFSNFNGTVKDDFSEFDNLRASKKPAESGASVPPQDSRTTSPDLFESQPLTSASSKPSSARKTPESFLGPNAALVNLDSLVTKPAPPAQSLNPFLAPGAATSTPVNPFQVNQPQPLTLNQLRGSPVLGSSASFGSGPGMEPVAPVTSVAPPSALGASGSSLTPLGPTAMNMIVQARSRSACWGPVILLQKMRALLTEAPPY", "length": 603, "header": "tr|A0A9J7H5N6-1|A0A9J7H5N6_CRIGR Isoform 1 of Epsin-2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Epn2 PE=3 SV=1 CANONICAL=A0A9J7H5N6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 569, "start_aa": "Thr", "end_pos": 569, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr569", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDY0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDY0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774824", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774824", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "clathrin vesicle coat", "id": "GO:0030125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030125", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6" } ], "pmid": "" }, { "name": "clathrin binding", "id": "GO:0030276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030276", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H5N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N6" }, { "id": "PS50942", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50942" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ENTH", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 144, "start_aa": "Asn", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 569 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 16, "end_pos": 18 }, { "start_pos": 176, "end_pos": 178 }, { "start_pos": 322, "end_pos": 324 }, { "start_pos": 335, "end_pos": 337 }, { "start_pos": 408, "end_pos": 410 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H5J1-1", "uniprot_ac": "A0A9J7H5J1", "uniprot_id": "A0A9J7H5J1_CRIGR", "mass": { "chemical_mass": 71398.0, "monoisotopic_mass": 71398.0 }, "refseq": { "ac": "XP_035305233", "name": "POU domain, class 2, transcription factor 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305233" }, "gene_names": [ { "name": "Pou2f2", "type": "recommended", "evidence": [ { "id": "A0A9J7H5J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1" } ] }, { "name": "Pou2f2", "type": "synonym", "evidence": [ { "id": "XP_035305233", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305233" } ] } ], "protein_names": [ { "name": "POU domain protein", "type": "recommended", "evidence": [ { "id": "A0A9J7H5J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1/entry#names_and_taxonomy" } ] }, { "name": "POU domain, class 2, transcription factor 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305233", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305233" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305233", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305233" } ] }, { "annotation": "Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5J1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1#function" }, { "database": "UniProtKB", "id": "ARBA00024760", "url": "https://www.uniprot.org/uniprotkb/ARBA00024760#function" }, { "database": "UniProtKB", "id": "A0A9J7H6H3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6H3#function" }, { "database": "UniProtKB", "id": "A0A9J7GGG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGG1#function" }, { "database": "UniProtKB", "id": "A0A9J7GGN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGN6#function" }, { "database": "UniProtKB", "id": "A0A9J7GHR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHR2#function" }, { "database": "UniProtKB", "id": "A0A9J7GL71", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GL71#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5J1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pou2f2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1", "locus": {} } ], "crossref": [ { "id": "A0A9J7H5J1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H5J1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757341", "url": "https://www.ncbi.nlm.nih.gov/gene/100757341", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045703", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045703", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757341", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757341", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H5J1", "url": "https://www.orthodb.org/?gene=A0A9J7H5J1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H7B7", "url": "https://www.orthodb.org/?gene=A0A9J7H7B7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11636", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11636", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11636:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11636:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00157", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00157", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305233", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305233", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M1N1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1N1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M1N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1N1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GGG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GGG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GGN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GGN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GHR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GHR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GL71", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GL71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GL71-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GL71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5J1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6H3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7B7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7B7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7B7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVHSSMGAPEIRMSKPLEAEKQSLDSPSEHTDTERNGPDINHQNPQNKASPFSVSPTGPSTKIKAEDPSGDSAQAAPPPPQPAQPHLPQAQLMLTGSQLAGLTALMPAQQQLLLQQAQAQLLAAAVQQSSAAAAANAAAAAAAASSSSSSASSSSASSASASQPPASSSGGGDLPPSQPASQPPGTPQLTLSQPIQLTAQDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAALPTQAVTRPTLPDPHLSHPQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGSTMVGLSSGLSPALMSNNPLATIQALASGGTLPLTSLDGSGNLVLGAAGAAPGSPGLVTSPLFLNHAGLPLLSAPPGVGLVSAAAAAVAASISSKSPGLSSSSSSSSSSSSTCSEVAAQTPGGPGGPEAGSKAE", "length": 700, "header": "tr|A0A9J7H5J1-1|A0A9J7H5J1_CRIGR Isoform 1 of POU domain protein OS=Cricetulus griseus OX=10029 GN=Pou2f2 PE=3 SV=1 CANONICAL=A0A9J7H5J1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M1N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1/entry#A0A8C2M1N1-1", "sequence": { "sequence": "MVHSSMGAPEIRMSKPLEAEKQSLDSPSEHTDTERNGPDINHQNPQNKASPFSVSPTGPSTKVGILSGLHLTFWGPGPCLSPPQIKAEDPSGDSAQAAPPPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAALPTQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGPGLWWNPAPYQP", "length": 485, "header": "tr|A0A8C2M1N1-1|A0A9J7H5J1_CRIGR Computationally mapped isoform of POU domain protein OS=Cricetulus griseus OX=10029 GN=Pou2f2 PE=3 SV=1 CANONICAL=A0A9J7H5J1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GGG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1/entry#A0A9J7GGG1-1", "sequence": { "sequence": "MVHSSMGAPEIRMSKPLEAEKQSLDSPSEHTDTERNGPDINHQNPQNKASPFSVSPTGPSTKIKAEDPSGDSAQAAPPPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAALPTQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGSTMVGLSSGLSPALMSNNPLATIQALASGGTLPLTSLDGSGNLVLGAAGAAPGSPGLVTSPLFLNHAGLPLLSAPPGVGLVSAAAAAVAASISSKSPGLSSSSSSSSSSSSTCSEVAAQTPGGPGGPEAGSKAE", "length": 585, "header": "tr|A0A9J7GGG1-1|A0A9J7GGG1_CRIGR Computationally mapped isoform of POU domain protein OS=Cricetulus griseus OX=10029 GN=Pou2f2 PE=3 SV=1 CANONICAL=A0A9J7H5J1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GGN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1/entry#A0A9J7GGN6-1", "sequence": { "sequence": "MVHSSMGAPEIRMSKPLEAEKQSLDSPSEHTDTERNGPDINHQNPQNKASPFSVSPTGPSTKIKAEDPSGDSAQAAPPPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAALPTQAVTRPTLPDPHLSHPQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGSTMVGLSSGLSPALMSNNPLATIQALASGGTLPLTSLDGSGNLVLGAAGAAPGSPGLVTSPLFLNHAGLPLLSAPPGVGLVSAAAAAVAASISSKSPGLSSSSSSSSSSSSTCSEVAAQTPGGPGGPEAGSKAE", "length": 601, "header": "tr|A0A9J7GGN6-1|A0A9J7GGN6_CRIGR Computationally mapped isoform of POU domain protein OS=Cricetulus griseus OX=10029 GN=Pou2f2 PE=3 SV=1 CANONICAL=A0A9J7H5J1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GHR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1/entry#A0A9J7GHR2-1", "sequence": { "sequence": "MVHSSMGAPEIRMSKPLEAEKQSLDSPSEHTDTERNGPDINHQNPQNKASPFSVSPTGPSTKVGILSGLHLTFWGPGPCLSPPQIKAEDPSGDSAQAAPPPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAALPTQAVTRPTLPDPHLSHPQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGSTMVGLSSGLSPALMSNNPLATIQALASGGTLPLTSLDGSGNLVLGAAGAAPGSPGLVTSPLFLNHAGLPLLSAPPGVGLVSAAAAAVAASISSKSPGLSSSSSSSSSSSSTCSEVAAQTPGGPGGPEAGSKAE", "length": 623, "header": "tr|A0A9J7GHR2-1|A0A9J7GHR2_CRIGR Computationally mapped isoform of POU domain protein OS=Cricetulus griseus OX=10029 GN=Pou2f2 PE=3 SV=1 CANONICAL=A0A9J7H5J1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GJK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1/entry#A0A9J7GJK3-1", "sequence": { "sequence": "MVHSSMGAPEIRMSKPLEAEKQSLDSPSEHTDTERNGPDINHQNPQNKASPFSVSPTGPSTKIKAEDPSGDSAQAAPPPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAALPTQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGPGLWWNPAPYQP", "length": 463, "header": "tr|A0A9J7GJK3-1|A0A9J7GJK3_CRIGR Computationally mapped isoform of POU domain protein OS=Cricetulus griseus OX=10029 GN=Pou2f2 PE=3 SV=1 CANONICAL=A0A9J7H5J1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GJM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1/entry#A0A9J7GJM0-1", "sequence": { "sequence": "MVHSSMGAPEIRMSKPLEAEKQSLDSPSEHTDTERNGPDINHQNPQNKASPFSVSPTGPSTKIKAEDPSGDSAQAAPPPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAALPTQAVTRPTLPDPHLSHPQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGPGLWWNPAPYQP", "length": 479, "header": "tr|A0A9J7GJM0-1|A0A9J7GJM0_CRIGR Computationally mapped isoform of POU domain protein OS=Cricetulus griseus OX=10029 GN=Pou2f2 PE=3 SV=1 CANONICAL=A0A9J7H5J1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GL71-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1/entry#A0A9J7GL71-1", "sequence": { "sequence": "MVHSSMGAPEIRMSKPLEAEKQSLDSPSEHTDTERNGPDINHQNPQNKASPFSVSPTGPSTKDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAALPTQAVTRPTLPDPHLSHPQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGSTMVGLSSGLSPALMSNNPLATIQALASGGTLPLTSLDGSGNLVLGAAGAAPGSPGLVTSPLFLNHAGLPLLSAPPGVGLVSAAAAAVAASISSKSPGLSSSSSSSSSSSSTCSEVAAQTPGGPGGPEAGSKAE", "length": 562, "header": "tr|A0A9J7GL71-1|A0A9J7GL71_CRIGR Computationally mapped isoform of POU domain protein OS=Cricetulus griseus OX=10029 GN=Pou2f2 PE=3 SV=1 CANONICAL=A0A9J7H5J1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H5J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1/entry#A0A9J7H5J1-1", "sequence": { "sequence": "MVHSSMGAPEIRMSKPLEAEKQSLDSPSEHTDTERNGPDINHQNPQNKASPFSVSPTGPSTKIKAEDPSGDSAQAAPPPPQPAQPHLPQAQLMLTGSQLAGLTALMPAQQQLLLQQAQAQLLAAAVQQSSAAAAANAAAAAAAASSSSSSASSSSASSASASQPPASSSGGGDLPPSQPASQPPGTPQLTLSQPIQLTAQDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAALPTQAVTRPTLPDPHLSHPQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGSTMVGLSSGLSPALMSNNPLATIQALASGGTLPLTSLDGSGNLVLGAAGAAPGSPGLVTSPLFLNHAGLPLLSAPPGVGLVSAAAAAVAASISSKSPGLSSSSSSSSSSSSTCSEVAAQTPGGPGGPEAGSKAE", "length": 700, "header": "tr|A0A9J7H5J1-1|A0A9J7H5J1_CRIGR Isoform 1 of POU domain protein OS=Cricetulus griseus OX=10029 GN=Pou2f2 PE=3 SV=1 CANONICAL=A0A9J7H5J1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H6H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1/entry#A0A9J7H6H3-1", "sequence": { "sequence": "MDPTLTTRTPRIRLPHSLCPQLAPAPRTYSNSSSSNSWCLSPATTSSHLRSSCCHRPSRVSQVRSQPSWCPPTCLQSSITWPHPLTSCLLVSPGLLPTPNLFQLPQQTQGALLTSQPRAALPTQAVTRPTLPDPHLSHPQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGSTMVGLSSGLSPALMSNNPLATIQALASGGTLPLTSLDGSGNLVLGAAGAAPGSPGLVTSPLFLNHAGLPLLSAPPGVGLVSAAAAAVAASISSKSPGLSSSSSSSSSSSSTCSEVAAQTPGGPGGPEAGSKAE", "length": 558, "header": "tr|A0A9J7H6H3-1|A0A9J7H6H3_CRIGR Computationally mapped isoform of POU domain protein OS=Cricetulus griseus OX=10029 GN=Pou2f2 PE=3 SV=1 CANONICAL=A0A9J7H5J1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1/entry#A0A9J7H7B7-1", "sequence": { "sequence": "MVHSSMGAPEIRMSKPLEAEKQSLDSPSEHTDTERNGPDINHQNPQNKASPFSVSPTGPSTKVGILSGLHLTFWGPGPCLSPPQIKAEDPSGDSAQAAPPPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAALPTQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGSTMVGLSSGLSPALMSNNPLATIQGACCLVSPHCHQPRPLLGLEPPHRCPSHATLPCSPHCLSLHPHLSLGKV", "length": 546, "header": "tr|A0A9J7H7B7-1|A0A9J7H7B7_CRIGR Computationally mapped isoform of POU domain protein OS=Cricetulus griseus OX=10029 GN=Pou2f2 PE=3 SV=1 CANONICAL=A0A9J7H5J1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": 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"evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5J1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5J1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5J1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H5J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 394, "end_pos": 454, "start_aa": "Gly", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H5J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J1" }, { "id": "PS51179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "POU-specific", "eco_id": "ECO_0000259", "start_pos": 294, "end_pos": 368, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 57 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 347, "end_pos": 349 }, { "start_pos": 543, "end_pos": 545 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": 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"table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HA11-1", "uniprot_ac": "A0A9J7HA11", "uniprot_id": "A0A9J7HA11_CRIGR", "mass": { "chemical_mass": 38848.0, "monoisotopic_mass": 38848.0 }, "refseq": { "ac": "XP_007646342", "name": "probable G-protein coupled receptor 174 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646342" }, "gene_names": [ { "name": "Gpr174", "type": "recommended", "evidence": [ { "id": "A0A9J7HA11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA11" } ] }, { "name": "Gpr174", "type": "synonym", "evidence": [ { "id": "XP_007646342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646342" } ] } ], "protein_names": [ { "name": "Probable G-protein coupled receptor 174", "type": "recommended", "evidence": [ { "id": "A0A9J7HA11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA11/entry#names_and_taxonomy" } ] }, { "name": "probable G-protein coupled receptor 174 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007646342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646342" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614404.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007646342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646342" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA11", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA11" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gpr174", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA11", "locus": {} } ], "crossref": [ { "id": "cd15152", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15152", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756360", "url": "https://www.ncbi.nlm.nih.gov/gene/100756360", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756360", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756360", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YLFLMHP", "url": "https://omabrowser.org/oma/group/YLFLMHP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7HA11", "url": "https://www.orthodb.org/?gene=A0A9J7HA11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232:SF86", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232:SF86", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007646342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646342", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M8C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M8C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M8C7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA11", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA11-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIDNYTCNKTEGDNIDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVVFMINLAIADLLQILSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFNDCKQKYDLYISIVGWLIICLACLLFPLLRTNDDTPGNRTKCFVDLPTRNVNLAQSVAMITIGELVGFVTPLMIVLYCTWKTALSLQNKYPISQHLGEKKKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPIIYYFTTNEFRRRLSRQDLPESIQLHTKSYKIVSNHTTSTMGTDLC", "length": 335, "header": "tr|A0A9J7HA11-1|A0A9J7HA11_CRIGR Isoform 1 of Probable G-protein coupled receptor 174 OS=Cricetulus griseus OX=10029 GN=Gpr174 PE=4 SV=1 CANONICAL=A0A9J7HA11-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M8C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA11/entry#A0A8C2M8C7-1", "sequence": { "sequence": "MIDNYTCNKTEGDNIDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVVFMINLAIADLLQILSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFNDCKQKYDLYISIVGWLIICLACLLFPLLRTNDDTPGNRTKCFVDLPTRNVNLAQSVAMITIGELVGFVTPLMIVLYCTWKTALSLQNKYPISQHLGEKKKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPIIYYFTTNEFRRRLSRQDLPESIQLHTKSYKIIFIVIQ", "length": 327, "header": "tr|A0A8C2M8C7-1|A0A9J7HA11_CRIGR Computationally mapped isoform of Probable G-protein coupled receptor 174 OS=Cricetulus griseus OX=10029 GN=Gpr174 PE=4 SV=1 CANONICAL=A0A9J7HA11-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HA11-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA11/entry#A0A9J7HA11-1", "sequence": { "sequence": "MIDNYTCNKTEGDNIDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVVFMINLAIADLLQILSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFNDCKQKYDLYISIVGWLIICLACLLFPLLRTNDDTPGNRTKCFVDLPTRNVNLAQSVAMITIGELVGFVTPLMIVLYCTWKTALSLQNKYPISQHLGEKKKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPIIYYFTTNEFRRRLSRQDLPESIQLHTKSYKIVSNHTTSTMGTDLC", "length": 335, "header": "tr|A0A9J7HA11-1|A0A9J7HA11_CRIGR Isoform 1 of Probable G-protein coupled receptor 174 OS=Cricetulus griseus OX=10029 GN=Gpr174 PE=4 SV=1 CANONICAL=A0A9J7HA11-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M8C7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M8C7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756360", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756360", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZWS1-1", "protein_name": "Probable G-protein coupled receptor 174", "gene_name": "Gpr174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTDNFTCNKTDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVVFMINLAIADLLQILSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFNDCKQKYDLYISIVGWLIICLACLLFPLLRTNDDTPGNRTKCFVDLPIRNVNLAQSVAMITIGEVVGFITPLMIVLYCTWKTALSLQNKYPISQHLGEKKKALRMILTCAAVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPVIYYFTTNEFRRRLSRQELPDSIQLQTKSYKIVNNHGASPTAAELC", "length": 335 }, "evidence": [ { "id": "A0A9J7HA11", "url": "https://omabrowser.org/oma/group/A0A9J7HA11/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RPF4-1", "protein_name": "Probable G-protein coupled receptor 174", "gene_name": "GPR174", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSANDTCPGTDGANTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGSGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLLYPFRFHDCKQKYDLYISIVGWLIICLACLLFPLLRSSDDTPGNKTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPVAQDLGEKKKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVIIIFHSVALCLASLNSCLDPVIYYFTTNEFRRRLSRQDLHDNIKLHAKSFVSNHITSTLRNEVC", "length": 333 }, "evidence": [ { "id": "A0A9J7HA11", "url": "https://omabrowser.org/oma/group/A0A9J7HA11/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G5E5R1-1", "protein_name": "Probable G-protein coupled receptor 174", "gene_name": "GPR174", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTANDTCAEINRDNTDSRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGSGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLLYPFRFHDCKQKYDLYISISGWLIICLACLLFPLLRSNDDTPSHRTKCFVDLPTRNVNLAQSVVMMTIGELIGFITPLLIVLFCTWKTVLSLQDKYPVAQDLGEKKKALKMILICAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPIIYYFTTDEFRRRLSRQELHDNIKLHAKSLVSNHTTSIVSTELC", "length": 333 }, "evidence": [ { "id": "A0A9J7HA11", "url": "https://omabrowser.org/oma/group/A0A9J7HA11/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3U507-1", "protein_name": "Probable G protein-coupled receptor 174", "gene_name": "Gpr174", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTDNFTCNKTDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVVFMINLAIADLLQILSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFNDCKQKYDLYISIIGWLIICLACLLFPLLRTNDDTPGNRTKCFVDLPIRNVNLAQSVAMITIGEVVGFVTPLMIVLYCTWKTALSLQNKYPISQHLGEKKKALKMILTCAGVFLVCFVPYHFSFPLDFLVKSNEIKSCFARRVILIFHSVALCLASLNSCLDPVIYYFTTNEFRRRLSRQDLPDNIQLHTKSYKIASNHATSTVAAELC", "length": 335 }, "evidence": [ { "id": "A0A9J7HA11", "url": "https://omabrowser.org/oma/group/A0A9J7HA11/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BXC1-1", "protein_name": "Probable G protein-coupled receptor 174", "gene_name": "GPR174", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLRTSDDTSGNRTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPMAQDLGEKQKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC", "length": 333 }, "evidence": [ { "id": "A0A9J7HA11", "url": "https://omabrowser.org/oma/group/A0A9J7HA11/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of interleukin-2 production", "id": "GO:0032703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032703", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA11", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA11" } ], "pmid": "" }, { "name": "phospholipase C-activating G protein-coupled receptor signaling pathway", "id": "GO:0007200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007200", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA11", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA11" } ], "pmid": "" }, { "name": "positive regulation of Rho protein signal transduction", "id": "GO:0035025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035025", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA11", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA11" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA11", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA11" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "bioactive lipid receptor activity", "id": "GO:0045125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045125", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA11", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA11" } ], "pmid": "" }, { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA11", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HA11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA11" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 292, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 4, "end_pos": 6 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", 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"uniprot_canonical_ac": "A0A9J7H7M5-1", "uniprot_ac": "A0A9J7H7M5", "uniprot_id": "A0A9J7H7M5_CRIGR", "mass": { "chemical_mass": 65683.0, "monoisotopic_mass": 65683.0 }, "refseq": { "ac": "XP_035306613", "name": "synembryn-B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306613" }, "gene_names": [ { "name": "Ric8b", "type": "recommended", "evidence": [ { "id": "A0A9J7H7M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5" } ] }, { "name": "Ric8b", "type": "synonym", "evidence": [ { "id": "XP_035306613", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306613" } ] } ], "protein_names": [ { "name": "Synembryn", "type": "recommended", "evidence": [ { "id": "A0A9J7H7M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5/entry#names_and_taxonomy" } ] }, { "name": "Protein Ric-8", "type": "synonym", "evidence": [ { "id": "A0A9J7H7M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5/entry#names_and_taxonomy" } ] }, { "name": "synembryn-B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035306613", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306613" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306613", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306613" } ] }, { "annotation": "Chaperone that specifically binds and folds nascent G alpha proteins prior to G protein heterotrimer formation. Also acts as a guanine nucleotide exchange factor (GEF) for G alpha proteins by stimulating exchange of bound GDP for free GTP.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7M0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M0#function" }, { "database": "UniProtKB", "id": "RU369048", "url": "https://www.uniprot.org/uniprotkb/RU369048#function" }, { "database": "UniProtKB", "id": "A0A8C2M9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9M0#function" }, { "database": "UniProtKB", "id": "A0A8C2MC51", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC51#function" }, { "database": "UniProtKB", "id": "A0A9J7H6S4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6S4#function" }, { "database": "UniProtKB", "id": "A0A9J7H7M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ric8b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5", "locus": {} } ], "crossref": [ { "id": "A0A9J7H7M5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H7M5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100762533", "url": "https://www.ncbi.nlm.nih.gov/gene/100762533", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019318", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019318", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762533", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762533", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H7M5", "url": "https://www.orthodb.org/?gene=A0A9J7H7M5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12425", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12425", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12425:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12425:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10165", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10165", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306613", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306613", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M9M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9M0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MC51", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MC51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6S4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6S4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7M0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEERALYIVRAGEAGAIERVLRDYSDKMRKPRCKELKSRPRSWTYIHRATFKFESTDEDKRKRLCEGIFKVLVKDVPTTCQVSCLEVLRILSRDKKILVPVTTKENMQILLKLAKLHESDDSLEKVSEFPVIVESLKCLCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIRSQLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPPLSPQETDCAIEALKALFNVTVDSWKVHKESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPLTHGETPQEAATLDELPGDKTTEKDTALKSNTMVYNGMNMEAVHVLLSFMEKRIDKGSSYREGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVKQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKNAKPNINLITGHLEEPMPNPIDEMTEEQKEYEAMKLVNMLDKLSREELLKPMGLKPDGTITPLEEALSQYSVIEETSSDTD", "length": 579, "header": "tr|A0A9J7H7M5-1|A0A9J7H7M5_CRIGR Isoform 1 of Synembryn OS=Cricetulus griseus OX=10029 GN=Ric8b PE=3 SV=1 CANONICAL=A0A9J7H7M5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M9M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5/entry#A0A8C2M9M0-1", "sequence": { "sequence": "MDEERALYIVRAGEAGAIERVLRDYSDKHRATFKFESTDEDKRKRLCEGIFKVLVKDVPTTCQVSCLEVLRILSRDKKILVPVTTKENMQILLKLAKLHESDDSLEKVSEFPVIVESLKCLCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIRSQLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPPLSPQETDCAIEALKALFNVTVDSWKVHKESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPLTHGETPQEAATLDELPGDKTTEKDTALKSNTMVYNGMNMEAVHVLLSFMEKRIDKGSSYREGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVKQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKNAKPKEELLKPMGLKPDGTITPLEEALSQYSVIEETSSDTD", "length": 520, "header": "tr|A0A8C2M9M0-1|A0A9J7H7M5_CRIGR Computationally mapped isoform of Synembryn OS=Cricetulus griseus OX=10029 GN=Ric8b PE=3 SV=1 CANONICAL=A0A9J7H7M5-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MC51-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5/entry#A0A8C2MC51-1", "sequence": { "sequence": "MDEERALYIVRAGEAGAIERVLRDYSDKHRATFKFESTDEDKRKRLCEGIFKVLVKDVPTTCQVSCLEVLRILSRDKKILVPVTTKENMQILLKLAKLHESDDSLEKVSEFPVIVESLKCLCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIRSQLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPPLSPQETDCAIEALKALFNVTVDSWKVHKESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPLTHGETPQEAATLDELPGDKTTEKDTALKSNTMVYNGMNMEAVHVLLSFMEKRIDKGSSYREGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVKQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKNAKPNINLITGHLEEPMPNPIDEMTEEQKEYEAMKLVNMLDKLSREELLKPMGLKPDGTITPLEEALSQYSVIEETSSDTD", "length": 560, "header": "tr|A0A8C2MC51-1|A0A9J7H7M5_CRIGR Computationally mapped isoform of Synembryn OS=Cricetulus griseus OX=10029 GN=Ric8b PE=3 SV=1 CANONICAL=A0A9J7H7M5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H6S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5/entry#A0A9J7H6S4-1", "sequence": { "sequence": "MDEERALYIVRAGEAGAIERVLRDYSDKMRKPRCKELKSRPRSWTYIHRATFKFESTDEDKRKRLCEGIFKVLVKDVPTTCQVSCLEVLRILSRDKKILVPVTTKENMQILLKLAKLHESDDSLEKVSEFPVIVESLKCLCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIRSQLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPPLSPQETDCAIEALKALFNVTVDSWKVHKESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPLTHGETPQEAATLDELPGDKTTEKDTALKSNTMVYNGMNMEAVHVLLSFMEKRIDKGSSYREGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVKQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKNAKPKEELLKPMGLKPDGTITPLEEALSQYSVIEETSSDTD", "length": 539, "header": "tr|A0A9J7H6S4-1|A0A9J7H6S4_CRIGR Computationally mapped isoform of Synembryn OS=Cricetulus griseus OX=10029 GN=Ric8b PE=3 SV=1 CANONICAL=A0A9J7H7M5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5/entry#A0A9J7H7M0-1", "sequence": { "sequence": "MDEERALYIVRAGEAGAIERVLRDYSDKMRKPRCKELKSRPRSWTYIHRATFKFESTDEDKRKRLCEGIFKVLVKDVPTTCQVSCLEVLRILSRDKKILVPVTTKENMQILLKLAKLHESDDSLEKVSEFPVIVESLKCLCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIRSQLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPPLSPQETDCAIEALKALFNVTVDSWKVHKESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPLTHGETPQEAATLDELPGDKTTEKDTALKSNTMVYNGMNMEAVHVLLSFMEKRIDKGSSYREGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVKQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKNAKPNINLITGHLEEPMPNPIDEMTEEQKEYEAMKLVNMLDKLSRRADVKDLHQDGG", "length": 555, "header": "tr|A0A9J7H7M0-1|A0A9J7H7M0_CRIGR Computationally mapped isoform of Synembryn OS=Cricetulus griseus OX=10029 GN=Ric8b PE=3 SV=1 CANONICAL=A0A9J7H7M5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5/entry#A0A9J7H7M5-1", "sequence": { "sequence": "MDEERALYIVRAGEAGAIERVLRDYSDKMRKPRCKELKSRPRSWTYIHRATFKFESTDEDKRKRLCEGIFKVLVKDVPTTCQVSCLEVLRILSRDKKILVPVTTKENMQILLKLAKLHESDDSLEKVSEFPVIVESLKCLCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIRSQLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPPLSPQETDCAIEALKALFNVTVDSWKVHKESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPLTHGETPQEAATLDELPGDKTTEKDTALKSNTMVYNGMNMEAVHVLLSFMEKRIDKGSSYREGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVKQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKNAKPNINLITGHLEEPMPNPIDEMTEEQKEYEAMKLVNMLDKLSREELLKPMGLKPDGTITPLEEALSQYSVIEETSSDTD", "length": 579, "header": "tr|A0A9J7H7M5-1|A0A9J7H7M5_CRIGR Isoform 1 of Synembryn OS=Cricetulus griseus OX=10029 GN=Ric8b PE=3 SV=1 CANONICAL=A0A9J7H7M5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9M0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M9M0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9M0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762533", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762533", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G-protein alpha-subunit binding", "id": "GO:0001965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001965", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HA03-1", "uniprot_ac": "A0A9J7HA03", "uniprot_id": "A0A9J7HA03_CRIGR", "mass": { "chemical_mass": 21741.0, "monoisotopic_mass": 21741.0 }, "refseq": { "ac": "XP_035308025", "name": "pulmonary surfactant-associated protein C isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308025" }, "gene_names": [ { "name": "Sftpc", "type": "recommended", "evidence": [ { "id": "A0A9J7HA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA03" } ] }, { "name": "Sftpc", "type": "synonym", "evidence": [ { "id": "XP_035308025", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308025" } ] } ], "protein_names": [ { "name": "Surfactant protein C", "type": "recommended", "evidence": [ { "id": "A0A9J7HA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA03/entry#names_and_taxonomy" } ] }, { "name": "Pulmonary surfactant-associated protein C", "type": "synonym", "evidence": [ { "id": "A0A9J7HA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA03/entry#names_and_taxonomy" } ] }, { "name": "Pulmonary surfactant-associated proteolipid SPL(Val)", "type": "synonym", "evidence": [ { "id": "A0A9J7HA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA03/entry#names_and_taxonomy" } ] }, { "name": "pulmonary surfactant-associated protein C isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035308025", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308025" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308025", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308025" } ] }, { "annotation": "Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA03#function" }, { "database": "UniProtKB", "id": "ARBA00002263", "url": "https://www.uniprot.org/uniprotkb/ARBA00002263#function" }, { "database": "UniProtKB", "id": "A0A8C2MBB4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBB4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA03" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sftpc", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA03", "locus": {} } ], "crossref": [ { "id": "A0A9J7HA03", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HA03", "database": "AlphaFoldDB", "categories": [] }, { "id": "100766762", "url": "https://www.ncbi.nlm.nih.gov/gene/100766762", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766762", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766762", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HA03", "url": "https://www.orthodb.org/?gene=A0A9J7HA03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10800", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10800", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10800:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10800:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08999", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08999", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308025", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308025", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MBB4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MBB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA03-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVGSKEVLMESPPDYSAGPRSQFRIPCCPVHLKRLLIVVVVVVLVVVVIVGALLMGLHMSQKHTEMVLEMSIGAPETQKRLALSEHMDTIATFSVGSTGIVVYDYQRLLTAYKPAPGTYCYIMKMDPGSIPSLEAFTRKFQNFKIEHMCSFQAKPSASTPKLGQEEGHGIGSESSGRDLAFLGLAVSTLCGELPLYYI", "length": 199, "header": "tr|A0A9J7HA03-1|A0A9J7HA03_CRIGR Isoform 1 of Surfactant protein C OS=Cricetulus griseus OX=10029 GN=Sftpc PE=4 SV=1 CANONICAL=A0A9J7HA03-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MBB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA03/entry#A0A8C2MBB4-1", "sequence": { "sequence": "MDVGSKEVLMESPPDYSAGPRSQFRIPCCPVHLKRLLIVVVVVVLVVVVIVGALLMGLHMSQKHTEMVLEMSIGAPETQKRLALSEHMDTIATFSVGSTGIVVYDYQRLLTAYKPAPGTYCYIMKMDPGSIPSLEAFTRKFQNFKAKPSASTPKLGQEEGHGIGSESSGRDLAFLGLAVSTLCGELPLYYI", "length": 191, "header": "tr|A0A8C2MBB4-1|A0A9J7HA03_CRIGR Computationally mapped isoform of Surfactant protein C OS=Cricetulus griseus OX=10029 GN=Sftpc PE=4 SV=1 CANONICAL=A0A9J7HA03-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HA03-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA03/entry#A0A9J7HA03-1", "sequence": { "sequence": "MDVGSKEVLMESPPDYSAGPRSQFRIPCCPVHLKRLLIVVVVVVLVVVVIVGALLMGLHMSQKHTEMVLEMSIGAPETQKRLALSEHMDTIATFSVGSTGIVVYDYQRLLTAYKPAPGTYCYIMKMDPGSIPSLEAFTRKFQNFKIEHMCSFQAKPSASTPKLGQEEGHGIGSESSGRDLAFLGLAVSTLCGELPLYYI", "length": 199, "header": "tr|A0A9J7HA03-1|A0A9J7HA03_CRIGR Isoform 1 of Surfactant protein C OS=Cricetulus griseus OX=10029 GN=Sftpc PE=4 SV=1 CANONICAL=A0A9J7HA03-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MBB4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBB4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MBB4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBB4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766762", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766762", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA03" } ], "pmid": "" }, { "name": "alveolar lamellar body", "id": "GO:0097208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097208", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA03" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "respiratory gaseous exchange by respiratory system", "id": "GO:0007585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007585", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA03" }, { "id": "PS50869", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50869" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BRICHOS", "eco_id": "ECO_0000259", "start_pos": 94, "end_pos": 199, "start_aa": "Phe", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H8U9-1", "uniprot_ac": "A0A9J7H8U9", "uniprot_id": "A0A9J7H8U9_CRIGR", "mass": { "chemical_mass": 55264.0, "monoisotopic_mass": 55264.0 }, "refseq": { "ac": "XP_035307768", "name": "noelin-3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307768" }, "gene_names": [ { "name": "Olfm3", "type": "recommended", "evidence": [ { "id": "A0A9J7H8U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U9" } ] }, { "name": "Olfm3", "type": "synonym", "evidence": [ { "id": "XP_035307768", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307768" } ] } ], "protein_names": [ { "name": "Noelin-3 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H8U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U9/entry#names_and_taxonomy" } ] }, { "name": "noelin-3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035307768", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307768" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307768", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307768" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8U9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Olfm3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U9", "locus": {} } ], "crossref": [ { "id": "A0A9J7H8U9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H8U9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100763639", "url": "https://www.ncbi.nlm.nih.gov/gene/100763639", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763639", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763639", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H8U9", "url": "https://www.orthodb.org/?gene=A0A9J7H8U9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12308", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12308", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307768", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307768", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MBC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MBC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8U9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAPLLKLGAVLSTMAMISNWMSQTLPSLVGLNTTRLSAPDTLVILIMQSPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLEKVQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQELKEKMDELLPLIPVLEQYKTDAKLITQFKEEIRNLSSVLTGIQEEIGAYDYEELHQRVLSLETRLRDCMKKLTCGKLMKITGPITVKTSGTRFGAWMTDPLASEKHNRVWYMDSYTNNKIVREYKSIADFVSGAESRTYNLPFKWAGTNHVVYNGSLYFNKYQSNIIIKYSFDLGRVLAQRSLEYAGFHNVYPYTWGGFSDIDLMADEIGLWAVYATNQNAGNIVISQLNQDTLEVMKSWSTGYPKRSAGESFMICGTLYVTNSHLTGAKVYYSYSTKTSTYEYTDIPFHNQYFHISMLDYNARDRALYAWNNGHQVLFNVTLFHIIKTEDDT", "length": 481, "header": "tr|A0A9J7H8U9-1|A0A9J7H8U9_CRIGR Isoform 1 of Noelin-3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Olfm3 PE=4 SV=1 CANONICAL=A0A9J7H8U9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MBC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U9/entry#A0A8C2MBC2-1", "sequence": { "sequence": "MSAPLLKLGAVLSTMAMISNWMSQTLPSLVGLNTTRLSAPDTLTQISPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLEKVQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQELKEKMDELLPLIPVLEQYKTDAKLITQFKEEIRNLSSVLTGIQEEIGAYDYEELHQRVLSLETRLRDCMKKLTCGKLMKITGPITVKTSGTRFGAWMTDPLASEKHNRVWYMDSYTNNKIVREYKSIADFVSGAESRTYNLPFKWAGTNHVVYNGSLYFNKYQSNIIIKYSFDLGRVLAQRSLEYAGFHNVYPYTWGGFSDIDLMADEIGLWAVYATNQNAGNIVISQLNQDTLEVMKSWSTGYPKRSAGESFMICGTLYVTNSHLTGAKVYYSYSTKTSTYEYTDIPFHNQYFHISMLDYNARDRALYAWNNGHQVLFNVTLFHIIKTEDDT", "length": 478, "header": "tr|A0A8C2MBC2-1|A0A9J7H8U9_CRIGR Computationally mapped isoform of Noelin-3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Olfm3 PE=4 SV=1 CANONICAL=A0A9J7H8U9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H8U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U9/entry#A0A9J7H8U9-1", "sequence": { "sequence": "MSAPLLKLGAVLSTMAMISNWMSQTLPSLVGLNTTRLSAPDTLVILIMQSPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLEKVQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQELKEKMDELLPLIPVLEQYKTDAKLITQFKEEIRNLSSVLTGIQEEIGAYDYEELHQRVLSLETRLRDCMKKLTCGKLMKITGPITVKTSGTRFGAWMTDPLASEKHNRVWYMDSYTNNKIVREYKSIADFVSGAESRTYNLPFKWAGTNHVVYNGSLYFNKYQSNIIIKYSFDLGRVLAQRSLEYAGFHNVYPYTWGGFSDIDLMADEIGLWAVYATNQNAGNIVISQLNQDTLEVMKSWSTGYPKRSAGESFMICGTLYVTNSHLTGAKVYYSYSTKTSTYEYTDIPFHNQYFHISMLDYNARDRALYAWNNGHQVLFNVTLFHIIKTEDDT", "length": 481, "header": "tr|A0A9J7H8U9-1|A0A9J7H8U9_CRIGR Isoform 1 of Noelin-3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Olfm3 PE=4 SV=1 CANONICAL=A0A9J7H8U9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MBC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBC2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MBC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBC2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763639", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763639", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8U9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8U9", 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309235", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309235" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ikzf1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2", "locus": {} } ], "crossref": [ { "id": "A0A9J7HBM2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HBM2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100759224", "url": "https://www.ncbi.nlm.nih.gov/gene/100759224", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", 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"MDTDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSERGMASNVKVETQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCDICGIICIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGTMYPVIKEETNHSEMAEDLCKIGAERSLVLDRLASNVAKRKSSMPQKFLGDKCLSDMPYDSASYEKDEMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPTDGPPRSNHSAQDSASAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHITPHVRNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLN", "length": 519, "header": "tr|A0A9J7HBM2-1|A0A9J7HBM2_CRIGR Isoform 1 of DNA-binding protein Ikaros isoform X1 OS=Cricetulus griseus OX=10029 GN=Ikzf1 PE=3 SV=1 CANONICAL=A0A9J7HBM2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MGE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2/entry#A0A8C2MGE7-1", "sequence": { "sequence": "MDTDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSERGMGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGTMYPVIKEETNHSEMAEDLCKIGAERSLVLDRLASNVAKRKSSMPQKFLGDKCLSDMPYDSASYEKDEMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPTDGPPRSNHSAQDSASAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHITPHVRNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLN", "length": 432, "header": "tr|A0A8C2MGE7-1|A0A9J7HBM2_CRIGR Computationally mapped isoform of DNA-binding protein Ikaros isoform X1 OS=Cricetulus griseus OX=10029 GN=Ikzf1 PE=3 SV=1 CANONICAL=A0A9J7HBM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HBM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2/entry#A0A9J7HBM2-1", "sequence": { "sequence": "MDTDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSERGMASNVKVETQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCDICGIICIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGTMYPVIKEETNHSEMAEDLCKIGAERSLVLDRLASNVAKRKSSMPQKFLGDKCLSDMPYDSASYEKDEMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPTDGPPRSNHSAQDSASAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHITPHVRNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLN", "length": 519, "header": "tr|A0A9J7HBM2-1|A0A9J7HBM2_CRIGR Isoform 1 of DNA-binding protein Ikaros isoform X1 OS=Cricetulus griseus OX=10029 GN=Ikzf1 PE=3 SV=1 CANONICAL=A0A9J7HBM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HBS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2/entry#A0A9J7HBS0-1", "sequence": { "sequence": "MDTDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSERGMGDKCLSDMPYDSASYEKDEMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPTDGPPRSNHSAQDSASAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHITPHVRNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLN", "length": 289, "header": "tr|A0A9J7HBS0-1|A0A9J7HBS0_CRIGR Computationally mapped isoform of DNA-binding protein Ikaros isoform X14 OS=Cricetulus griseus OX=10029 GN=Ikzf1 PE=4 SV=1 CANONICAL=A0A9J7HBM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HC33-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2/entry#A0A9J7HC33-1", "sequence": { "sequence": "MDTDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSERGMVAYGADGFRDFHAIIPKSFSRERPFQCNQCGASFTQKGNLLRHIKLHKPPTDGPPRSNHSAQDSASAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHITPHVRNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLN", "length": 270, "header": "tr|A0A9J7HC33-1|A0A9J7HC33_CRIGR Computationally mapped isoform of DNA-binding protein Ikaros isoform X15 OS=Cricetulus griseus OX=10029 GN=Ikzf1 PE=4 SV=1 CANONICAL=A0A9J7HBM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HC59-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2/entry#A0A9J7HC59-1", "sequence": { "sequence": "MDTDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSERGMGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGTMYPVIKEETNHSEMAEDLCKIGAERSLVLDRLASNVAKRDKCLSDMPYDSASYEKDEMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPTDGPPRSNHSAQDSASAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHITPHVRNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLN", "length": 422, "header": "tr|A0A9J7HC59-1|A0A9J7HC59_CRIGR Computationally mapped isoform of DNA-binding protein Ikaros isoform X6 OS=Cricetulus griseus OX=10029 GN=Ikzf1 PE=3 SV=1 CANONICAL=A0A9J7HBM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HCS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2/entry#A0A9J7HCS8-1", "sequence": { "sequence": "MDTDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSERGMASNVKVETQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCDICGIICIGPNVLMVHKRSHTGDKCLSDMPYDSASYEKDEMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPTDGPPRSNHSAQDSASAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHITPHVRNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLN", "length": 376, "header": "tr|A0A9J7HCS8-1|A0A9J7HCS8_CRIGR Computationally mapped isoform of DNA-binding protein Ikaros isoform X8 OS=Cricetulus griseus OX=10029 GN=Ikzf1 PE=3 SV=1 CANONICAL=A0A9J7HBM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HE74-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2/entry#A0A9J7HE74-1", "sequence": { "sequence": "MDTDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSERGMVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGTMYPVIKEETNHSEMAEDLCKIGAERSLVLDRLASNVAKRKSSMPQKFLGDKCLSDMPYDSASYEKDEMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPTDGPPRSNHSAQDSASAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHITPHVRNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLN", "length": 376, "header": "tr|A0A9J7HE74-1|A0A9J7HE74_CRIGR Computationally mapped isoform of DNA-binding protein Ikaros isoform X10 OS=Cricetulus griseus OX=10029 GN=Ikzf1 PE=3 SV=1 CANONICAL=A0A9J7HBM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HF19-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2/entry#A0A9J7HF19-1", "sequence": { "sequence": "MDTDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSERGMASNVKVETQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCDICGIICIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGTMYPVIKEETNHSEMAEDLCKIGAERSLVLDRLASNVAKRDKCLSDMPYDSASYEKDEMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPTDGPPRSNHSAQDSASAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHITPHVRNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLN", "length": 509, "header": "tr|A0A9J7HF19-1|A0A9J7HF19_CRIGR Computationally mapped isoform of DNA-binding protein Ikaros isoform X2 OS=Cricetulus griseus OX=10029 GN=Ikzf1 PE=3 SV=1 CANONICAL=A0A9J7HBM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HF76-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2/entry#A0A9J7HF76-1", "sequence": { "sequence": "MDTDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSERGMASNVKVETQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCDICGIICIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSGDKCLSDMPYDSASYEKDEMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPTDGPPRSNHSAQDSASAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHITPHVRNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLN", "length": 432, "header": "tr|A0A9J7HF76-1|A0A9J7HF76_CRIGR Computationally mapped isoform of DNA-binding protein Ikaros isoform X4 OS=Cricetulus griseus OX=10029 GN=Ikzf1 PE=3 SV=1 CANONICAL=A0A9J7HBM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HGC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2/entry#A0A9J7HGC2-1", "sequence": { "sequence": "MDTDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSERGMGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVIKEETNHSEMAEDLCKIGAERSLVLDRLASNVAKRKSSMPQKFLGDKCLSDMPYDSASYEKDEMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPTDGPPRSNHSAQDSASAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHITPHVRNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLN", "length": 390, "header": "tr|A0A9J7HGC2-1|A0A9J7HGC2_CRIGR Computationally mapped isoform of DNA-binding protein Ikaros isoform X7 OS=Cricetulus griseus OX=10029 GN=Ikzf1 PE=4 SV=1 CANONICAL=A0A9J7HBM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K4P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2/entry#A0A9J7K4P8-1", "sequence": { "sequence": "MDTDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSERGMVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGTMYPVIKEETNHSEMAEDLCKIGAERSLVLDRLASNVAKRDKCLSDMPYDSASYEKDEMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPTDGPPRSNHSAQDSASAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHITPHVRNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLN", "length": 366, "header": "tr|A0A9J7K4P8-1|A0A9J7HBM2_CRIGR Computationally mapped isoform of DNA-binding protein Ikaros isoform X1 OS=Cricetulus griseus OX=10029 GN=Ikzf1 PE=3 SV=1 CANONICAL=A0A9J7HBM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KCL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2/entry#A0A9J7KCL3-1", "sequence": { "sequence": "MDTDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSERGMGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVIKEETNHSEMAEDLCKIGAERSLVLDRLASNVAKRDKCLSDMPYDSASYEKDEMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPTDGPPRSNHSAQDSASAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHITPHVRNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLN", "length": 380, "header": "tr|A0A9J7KCL3-1|A0A9J7HBM2_CRIGR Computationally mapped isoform of DNA-binding protein Ikaros isoform X1 OS=Cricetulus griseus OX=10029 GN=Ikzf1 PE=3 SV=1 CANONICAL=A0A9J7HBM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KES4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2/entry#A0A9J7KES4-1", "sequence": { "sequence": "MDTDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSERGMVIKEETNHSEMAEDLCKIGAERSLVLDRLASNVAKRDKCLSDMPYDSASYEKDEMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPTDGPPRSNHSAQDSASAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHITPHVRNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLN", "length": 324, "header": "tr|A0A9J7KES4-1|A0A9J7HBM2_CRIGR Computationally mapped isoform of DNA-binding protein Ikaros isoform X1 OS=Cricetulus griseus OX=10029 GN=Ikzf1 PE=3 SV=1 CANONICAL=A0A9J7HBM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KFN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2/entry#A0A9J7KFN6-1", "sequence": { "sequence": "MDTDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSERGMASNVKVETQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCDICGIICIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVIKEETNHSEMAEDLCKIGAERSLVLDRLASNVAKRKSSMPQKFLGDKCLSDMPYDSASYEKDEMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPTDGPPRSNHSAQDSASAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHITPHVRNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLN", "length": 477, "header": "tr|A0A9J7KFN6-1|A0A9J7HBM2_CRIGR Computationally mapped isoform of DNA-binding protein Ikaros isoform X1 OS=Cricetulus griseus OX=10029 GN=Ikzf1 PE=3 SV=1 CANONICAL=A0A9J7HBM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KFS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2/entry#A0A9J7KFS7-1", "sequence": { "sequence": "MDTDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSERGMVIKEETNHSEMAEDLCKIGAERSLVLDRLASNVAKRKSSMPQKFLGDKCLSDMPYDSASYEKDEMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPTDGPPRSNHSAQDSASAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHITPHVRNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLN", "length": 334, "header": "tr|A0A9J7KFS7-1|A0A9J7HBM2_CRIGR Computationally mapped isoform of DNA-binding protein Ikaros isoform X1 OS=Cricetulus griseus OX=10029 GN=Ikzf1 PE=3 SV=1 CANONICAL=A0A9J7HBM2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K4P8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4P8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K4P8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4P8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759224", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759224", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2" } ], "pmid": "" }, { "name": "B cell differentiation", "id": "GO:0030183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030183", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2" } ], "pmid": "" }, { "name": "T cell differentiation", "id": "GO:0030217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030217", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2" } ], "pmid": "" }, { "name": "regulation of lymphocyte differentiation", "id": "GO:0045619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045619", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2" } ], "pmid": "" }, { "name": "lymphocyte differentiation", "id": "GO:0030098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030098", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HBM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBM2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 117, "end_pos": 144, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 245, "end_pos": 247 }, { "start_pos": 360, "end_pos": 362 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303239", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303239" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5F4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Git1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5F4", "locus": {} } ], "crossref": [ { "id": "A0A9J7H5F4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H5F4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08846", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08846", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758194", "url": "https://www.ncbi.nlm.nih.gov/gene/100758194", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758194", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758194", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H5F4", "url": "https://www.orthodb.org/?gene=A0A9J7H5F4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46097", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46097", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46097:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46097:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08518", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08518", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16559", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16559", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303239", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303239", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MHZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MHZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MHZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5F4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLPLVSWKLSLPSPGHRLAWNGRAILHCCGVSLGAFQVPSDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMADSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLATQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLIIDILSEAKRRQQGKSLSSPTDNLELSAQSQSDLDDQHDYDSVASDEDTDQEPLPSTGATRNNRARSMDSSDLSDGAVTLQEYLELKKALATSEARVEQLMQVNSSLSDELRRLQREIHKLQAENLQLRQPSGPTPTPPLPNERAEHVPMGPAGSTHRRDRQAFSMYEPGSALKPFGGAPGDELTTRLQPFHSTELEDDAIYSVHVPTGLYRIRKGVSASSVPFTPSSPLLSCSPEGSRHTSKLSRHGSGADSDYENTQSGDPPLGLEGKRFLELGKEDELHPELESLEGDLDPGLPSTEDVILKTEQVTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFPKRPALEPVRNSLRLLNASAYRLQSECRKTVPPEPGAPVDFQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ", "length": 785, "header": "tr|A0A9J7H5F4-1|A0A9J7H5F4_CRIGR Isoform 1 of ARF GTPase-activating protein GIT1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Git1 PE=4 SV=1 CANONICAL=A0A9J7H5F4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MHZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5F4/entry#A0A8C2MHZ7-1", "sequence": { "sequence": "MSRKGPRAEVCADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMADSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLATQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLIIDILSEAKRRQQGKSLSSPTDNLELSAQSQSDLDDQHDYDSVASDEDTDQEPLPSTGATRNNRARSMDSSDLSDGAVTLQEYLELKKALATSEARVEQLMQVNSSLSDELRRLQREIHKLQAENLQLRQPSGPTPTPPLPNERAEHVPMGPAGSTHRRDRQAFSMYEPGSALKPFGGAPGDELTTRLQPFHSTELEDDAIYSVHVPTGLYRIRKGVSASSVPFTPSSPLLSCSPEGSRHTSKLSRHGSGADSDYENTQSGDPPLGLEGKRFLELGKEDELHPELESLEGDLDPGLPSTEDVILKTEQVTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFPKRPALEPVRNSLRLLNASAYRLQSECRKTVPPEPGAPVDFQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ", "length": 761, "header": "tr|A0A8C2MHZ7-1|A0A9J7H5F4_CRIGR Computationally mapped isoform of ARF GTPase-activating protein GIT1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Git1 PE=4 SV=1 CANONICAL=A0A9J7H5F4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H5F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5F4/entry#A0A9J7H5F4-1", "sequence": { "sequence": "MSLPLVSWKLSLPSPGHRLAWNGRAILHCCGVSLGAFQVPSDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMADSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLATQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLIIDILSEAKRRQQGKSLSSPTDNLELSAQSQSDLDDQHDYDSVASDEDTDQEPLPSTGATRNNRARSMDSSDLSDGAVTLQEYLELKKALATSEARVEQLMQVNSSLSDELRRLQREIHKLQAENLQLRQPSGPTPTPPLPNERAEHVPMGPAGSTHRRDRQAFSMYEPGSALKPFGGAPGDELTTRLQPFHSTELEDDAIYSVHVPTGLYRIRKGVSASSVPFTPSSPLLSCSPEGSRHTSKLSRHGSGADSDYENTQSGDPPLGLEGKRFLELGKEDELHPELESLEGDLDPGLPSTEDVILKTEQVTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFPKRPALEPVRNSLRLLNASAYRLQSECRKTVPPEPGAPVDFQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ", "length": 785, "header": "tr|A0A9J7H5F4-1|A0A9J7H5F4_CRIGR Isoform 1 of ARF GTPase-activating protein GIT1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Git1 PE=4 SV=1 CANONICAL=A0A9J7H5F4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5F4/entry#A0A9J7KBA6-1", "sequence": { "sequence": "MSLPLVSWKLSLPSPGHRLAWNGRAILHCCGVSLGAFQVPSDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMADSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLATQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLIIDILSEAKRRQQGKSLSSPTDNLELSAQSQSDLDDQHDYDSVASDEDTDQEPLPSTGATRNNRARSMDSSDLSDGAVTLQEYLELKKALATSEARVEQLMQVNSSLSDELRRLQREAENLQLRQPSGPTPTPPLPNERAEHVPMGPAGSTHRRDRQAFSMYEPGSALKPFGGAPGDELTTRLQPFHSTELEDDAIYSVHVPTGLYRIRKGVSASSVPFTPSSPLLSCSPEGSRHTSKLSRHGSGADSDYENTQSGDPPLGLEGKRFLELGKEDELHPELESLEGDLDPGLPSTEDVILKTEQVTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFPKRPALEPVRNSLRLLNASAYRLQSECRKTVPPEPGAPVDFQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ", "length": 780, "header": "tr|A0A9J7KBA6-1|A0A9J7H5F4_CRIGR Computationally mapped isoform of ARF GTPase-activating protein GIT1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Git1 PE=4 SV=1 CANONICAL=A0A9J7H5F4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 502, "start_aa": "Thr", "end_pos": 502, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr502", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 504, "start_aa": "Thr", "end_pos": 504, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr504", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBA6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"tr|A0A9J7H5H3-1|A0A9J7H5H3_CRIGR Isoform 1 of ETS homologous factor OS=Cricetulus griseus OX=10029 GN=Ehf PE=3 SV=1 CANONICAL=A0A9J7H5H3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MJL0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJL0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MJL0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJL0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774359", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774359", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5H3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5H3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5H3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5H3" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5H3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5H3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5H3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5H3" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5H3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5H3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H5H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5H3" }, { "id": "PS50061", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ETS", "eco_id": "ECO_0000259", "start_pos": 207, "end_pos": 289, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H5H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5H3" }, { "id": "PS51433", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51433" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PNT", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 115, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 254, "end_pos": 256 }, { "start_pos": 255, "end_pos": 257 }, { "start_pos": 32, "end_pos": 34 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HB07-1", "uniprot_ac": "A0A9J7HB07", "uniprot_id": "A0A9J7HB07_CRIGR", "mass": { "chemical_mass": 100776.0, "monoisotopic_mass": 100776.0 }, "refseq": { "ac": "XP_035308616", "name": "oxysterol-binding protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308616" }, "gene_names": [ { "name": "Osbp2", "type": "recommended", "evidence": [ { "id": "A0A9J7HB07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB07" } ] }, { "name": "Osbp2", "type": "synonym", "evidence": [ { "id": "XP_035308616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308616" } ] } ], "protein_names": [ { "name": "Oxysterol-binding protein", "type": "recommended", "evidence": [ { "id": "A0A9J7HB07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB07/entry#names_and_taxonomy" } ] }, { "name": "oxysterol-binding protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035308616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308616" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308616" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB07", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB07" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Osbp2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB07", "locus": {} } ], "crossref": [ { "id": "A0A9J7HB07", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HB07", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13284", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13284", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760907", "url": "https://www.ncbi.nlm.nih.gov/gene/100760907", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760907", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760907", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HAG5", "url": "https://www.orthodb.org/?gene=A0A9J7HAG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7HB07", "url": "https://www.orthodb.org/?gene=A0A9J7HB07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972:SF194", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972:SF194", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308616", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MSC8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MSC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HB07", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HB07-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB07-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKAAAPTRGGGCAGRSRGLSSLFTVVPCLSCHTAAPGMNSSTSGSGPEPKPQLQPVQAPERELLDEQVCKPGFDPVPRSEPESQTTSVAGPSGAGQESELQGLCQDSEAGPRVGAGPFTQTTPEQLPLGSTAGTVPRSGPKPQALQRQGQAKTSAGSPGPGIGLPMVSPPLDSYKGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLASAHIDTEDSCGIMLCNGARTYHLKASSEVDRKQWITVLELAKAKAICVMKTQSDDSEDDDEEPAAPADKSELHHTIKNLSLKLDDLSTCNDLIAKHGAALQRSLNELDSLKIPSESGEKLKVVNERATLFRITSNAMINACKDFLELAETHSRKWQRALNYEQEQRVHLEETIEQLAKQHNSLERAFCNTPGGPANPSTSLSEGSFLTSKGENSEEDEDTEYFDAMEDSTSFITVITEAKEDRKAEGGSGPTSVDWTSADNVREVLDGASFVPKDSCKVKRRVRIPDKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVNCTNSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLEDMGLRSLCEQVSHHPPSAAHHVFSKHGWSLWQEITIASKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTKDRCQLKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKIVHSSPSSPNSDGKQKTVYQTLPAKLLWRKYPLPENAENMYYFSKLALTLNEQEDGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLETCAAGCGGEDEKESESHVPLWFEKRLDPLTGEMACMYKGGYWEAKEKKDWHMCPNIF", "length": 907, "header": "tr|A0A9J7HB07-1|A0A9J7HB07_CRIGR Isoform 1 of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbp2 PE=3 SV=1 CANONICAL=A0A9J7HB07-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MSC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB07/entry#A0A8C2MSC8-1", "sequence": { "sequence": "MGKAAAPTRGGGCAGRSRGLSSLFTVVPCLSCHTAAPGMNSSTSGSGPEPKPQLQPVQAPERELLDEQVCKPGFDPVPRSEPESQTTSVAGPSGAGQESELQGLCQDSEAGPRVGAGPFTQTTPEQLPLGSTAGTVPRSGPKPQALQRQGQAKTSAGSPGPGIGLPMVSPPLDSYKGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLASAHIDTEDSCGIMLCNGARTYHLKASSEVDRKQWITVLELAKAKAICVMKTQSDDSEDDDEEPAAPADKSELHHTIKNLSLKLDDLSTCNDLIAKHGAALQRSLNELDSLKIPSESGEKLKVVNERATLFRITSNAMINACKDFLELAETHSRKWQRALNYEQEQRVHLEETIEQLAKQHNSLERAFCNTPGGPANPSTSLSEGSFLTSKGENSEEDEDTEYFDAMEDSTSFITVITEAKEDRKAEGGSGPTSVDWTSADNVLDGASFVPKDSCKVKRRVRIPDKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVNCTNSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLEDMGLRSLCEQVSHHPPSAAHHVFSKHGWSLWQEITIASKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTKDRCQLKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKIVHSSPSSPNSDGKQKTVYQTLPAKLLWRKYPLPENAENMYYFSKLALTLNEQEDGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLETCAAGCGGEDEKESESHVPLWFEKRLDPLTGEMACMYKGGYWEAKEKKDWHMCPNIF", "length": 904, "header": "tr|A0A8C2MSC8-1|A0A9J7HB07_CRIGR Computationally mapped isoform of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbp2 PE=3 SV=1 CANONICAL=A0A9J7HB07-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB07/entry#A0A9J7HAG5-1", "sequence": { "sequence": "MKGRGCWETASVRSFCSSGCLNKFKKDDSEDDDEEPAAPADKSELHHTIKNLSLKLDDLSTCNDLIAKHGAALQRSLNELDSLKIPSESGEKLKVVNERATLFRITSNAMINACKDFLELAETHSRKWQRALNYEQEQRVHLEETIEQLAKQHNSLERAFCNTPGGPANPSTSLSEGSFLTSKGENSEEDEDTEYFDAMEDSTSFITVITEAKEDRKAEGGSGPTSVDWTSADNVLDGASFVPKDSCKVKRRVRIPDKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVNCTNSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLEDMGLRSLCEQVSHHPPSAAHHVFSKHGWSLWQEITIASKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTKDRCQLKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKIVHSSPSSPNSDGKQKTVYQTLPAKLLWRKYPLPENAENMYYFSKLALTLNEQEDGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLETCAAGCGGEDAEKESESHVPLWFEKRLDPLTGEMACMYKGGYWEAKEKKDWHMCPNIF", "length": 657, "header": "tr|A0A9J7HAG5-1|A0A9J7HAG5_CRIGR Computationally mapped isoform of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbp2 PE=3 SV=1 CANONICAL=A0A9J7HB07-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HB07-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB07/entry#A0A9J7HB07-1", "sequence": { "sequence": "MGKAAAPTRGGGCAGRSRGLSSLFTVVPCLSCHTAAPGMNSSTSGSGPEPKPQLQPVQAPERELLDEQVCKPGFDPVPRSEPESQTTSVAGPSGAGQESELQGLCQDSEAGPRVGAGPFTQTTPEQLPLGSTAGTVPRSGPKPQALQRQGQAKTSAGSPGPGIGLPMVSPPLDSYKGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLASAHIDTEDSCGIMLCNGARTYHLKASSEVDRKQWITVLELAKAKAICVMKTQSDDSEDDDEEPAAPADKSELHHTIKNLSLKLDDLSTCNDLIAKHGAALQRSLNELDSLKIPSESGEKLKVVNERATLFRITSNAMINACKDFLELAETHSRKWQRALNYEQEQRVHLEETIEQLAKQHNSLERAFCNTPGGPANPSTSLSEGSFLTSKGENSEEDEDTEYFDAMEDSTSFITVITEAKEDRKAEGGSGPTSVDWTSADNVREVLDGASFVPKDSCKVKRRVRIPDKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVNCTNSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLEDMGLRSLCEQVSHHPPSAAHHVFSKHGWSLWQEITIASKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTKDRCQLKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKIVHSSPSSPNSDGKQKTVYQTLPAKLLWRKYPLPENAENMYYFSKLALTLNEQEDGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLETCAAGCGGEDEKESESHVPLWFEKRLDPLTGEMACMYKGGYWEAKEKKDWHMCPNIF", "length": 907, "header": "tr|A0A9J7HB07-1|A0A9J7HB07_CRIGR Isoform 1 of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbp2 PE=3 SV=1 CANONICAL=A0A9J7HB07-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 473, "start_aa": "Thr", "end_pos": 473, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr473", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 811, "start_aa": "Thr", "end_pos": 811, "end_aa": "Thr", 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"database": "UniProtKB", "id": "A0A9J7H5G4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5G4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "all-trans-retinol dehydrogenase (NAD+) activity", "id": "GO:0004745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004745", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5G4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5G4" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "id": "GO:0016616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016616", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5G4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5G4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "sarcoplasmic reticulum membrane", "id": "GO:0033017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033017", "evidence": [ { "database": "UniProtKB", "id": 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Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308431" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAP5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAP5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rnf215", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAP5", "locus": {} } ], "crossref": [ { "id": "A0A9J7HAP5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HAP5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16670", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16670", "database": "CDD", "categories": [ "Protein Classification" ] 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308431", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MUG3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MUG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA49", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA49-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAP5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAP5", "database": "UniProtKB", 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"MGPADRPVLRSPPSPPPPPSPPSPLLLLLPLLPLWLGLAGPGAAADGSEPAARAGRGGARAVRVDVKLPRQDALVLEGVRIGPEADPEPLLGGRLLLILAASSTPLASLFSWLLTQMDVVDAEQEIPVDGWIAVAYVGKEQAAQFHQENQGSGPKTYPKALVQQMRRALFLGASALLLLILNHSVVRELDISQLLLRPVIVLHYSSNVTKLLEALLQRTQATAEITSRESLSANIEWKLTLWTTCGLSKDSYGGWQDLVCLGGGQAQEQKPLQQLWNAILLVAMLLCTGLVVQAQRQASRQNQQEPGGQGDLFKRRVVRRLASLKTRRCRLSRAAHSLPEPGMETCAVCLDNFCNKQWLRVLPCKHEFHRDCVDPWLMLQQTCPLCKFNVLGNHYSDD", "length": 398, "header": "tr|A0A9J7HAP5-1|A0A9J7HAP5_CRIGR Isoform 1 of RING finger protein 215 OS=Cricetulus griseus OX=10029 GN=Rnf215 PE=4 SV=1 CANONICAL=A0A9J7HAP5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MUG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAP5/entry#A0A8C2MUG3-1", "sequence": { "sequence": "MGPADRPVLRSPPSPPPPPSPPSPLLLLLPLLPLWLGLAGPGAAADGSEPAARAGRGGARAVRVDVKLPRQDALVLEGVRIGPEADPEPLLGGRLLLMDVVDAEQEIPVDGWIAVAYVGKEQAAQFHQENQGSGPKTYPKALVQQMRRALFLGASALLLLILNHSVVRELDISQLLLRPVIVLHYSSNVTKLLEALLQRTQATAEITSRESLSANIEWKLTLWTTCGLSKDSYGGWQDLVCLGGGQAQEQKPLQQLWNAILLVAMLLCTGLVVQAQRQASRQNQQEPGGQGDLFKRRVVRRLASLKTRRCRLSRAAHSLPEPGMETCAVCLDNFCNKQWLRVLPCKHEFHRDCVDPWLMLQQTCPLCKFNVLGNHYSDD", "length": 379, "header": "tr|A0A8C2MUG3-1|A0A9J7HAP5_CRIGR Computationally mapped isoform of RING finger protein 215 OS=Cricetulus griseus OX=10029 GN=Rnf215 PE=4 SV=1 CANONICAL=A0A9J7HAP5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HA49-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAP5/entry#A0A9J7HA49-1", "sequence": { "sequence": "MGPADRPVLRSPPSPPPPPSPPSPLLLLLPLLPLWLGLAGPGAAADGSEPAARAGRGGARAVRVDVKLPRQDALVLEGVRIGPEADPEPLLGGRLLLILAASSTPLASLFSWLLTQMDVVDAEQEIPVDGWIAVAYVGKEQAAQFHQENQGSGPKTYPKALVQQMRRALFLGASALLLLILNHSVVRELDISQLLLRPVIVLHYSSNVTKLLEALLQTQATAEITSRESLSANIEWKLTLWTTCGLSKDSYGGWQDLVCLGGGQAQEQKPLQQLWNAILLVAMLLCTGLVVQAQRQASRQNQQEPGGQGDLFKRRVVRRLASLKTRRCRLSRAAHSLPEPGMETCAVCLDNFCNKQWLRVLPCKHEFHRDCVDPWLMLQQTCPLCKFNVLGNHYSDD", "length": 397, "header": "tr|A0A9J7HA49-1|A0A9J7HA49_CRIGR Computationally mapped isoform of RING finger protein 215 OS=Cricetulus griseus OX=10029 GN=Rnf215 PE=4 SV=1 CANONICAL=A0A9J7HAP5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAP5/entry#A0A9J7HAP5-1", "sequence": { "sequence": "MGPADRPVLRSPPSPPPPPSPPSPLLLLLPLLPLWLGLAGPGAAADGSEPAARAGRGGARAVRVDVKLPRQDALVLEGVRIGPEADPEPLLGGRLLLILAASSTPLASLFSWLLTQMDVVDAEQEIPVDGWIAVAYVGKEQAAQFHQENQGSGPKTYPKALVQQMRRALFLGASALLLLILNHSVVRELDISQLLLRPVIVLHYSSNVTKLLEALLQRTQATAEITSRESLSANIEWKLTLWTTCGLSKDSYGGWQDLVCLGGGQAQEQKPLQQLWNAILLVAMLLCTGLVVQAQRQASRQNQQEPGGQGDLFKRRVVRRLASLKTRRCRLSRAAHSLPEPGMETCAVCLDNFCNKQWLRVLPCKHEFHRDCVDPWLMLQQTCPLCKFNVLGNHYSDD", "length": 398, "header": "tr|A0A9J7HAP5-1|A0A9J7HAP5_CRIGR Isoform 1 of RING finger protein 215 OS=Cricetulus griseus OX=10029 GN=Rnf215 PE=4 SV=1 CANONICAL=A0A9J7HAP5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HDP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAP5/entry#A0A9J7HDP6-1", "sequence": { "sequence": "MGPADRPVLRSPPSPPPPPSPPSPLLLLLPLLPLWLGLAGPGAAADGSEPAARAGRGGARAVRVDVKLPRQDALVLEGVRIGPEADPEPLLGGRLLLILAASSTPLASLFSWLLTQMDVVDAEQEIPVDGWIAVAYVGKEQAAQFHQENQGSGPKTYPKALVQQMRRALFLGASALLLLILNHSVVRELDISQLLLRPVIVLHYSSNVTKLLEALLQRTQATAEITSRESLSANIEWKLTLWTTCGLSKDSYGGWQDLVCLGGGQAQEQPLQQLWNAILLVAMLLCTGLVVQAQRQASRQNQQEPGGQGDLFKRRVVRRLASLKTRRCRLSRAAHSLPEPGMETCAVCLDNFCNKQWLRVLPCKHEFHRDCVDPWLMLQQTCPLCKFNVLGNHYSDD", "length": 397, "header": "tr|A0A9J7HDP6-1|A0A9J7HDP6_CRIGR Computationally mapped isoform of RING finger protein 215 OS=Cricetulus griseus OX=10029 GN=Rnf215 PE=4 SV=1 CANONICAL=A0A9J7HAP5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KF46-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAP5/entry#A0A9J7KF46-1", "sequence": { "sequence": "MGPADRPVLRSPPSPPPPPSPPSPLLLLLPLLPLWLGLAGPGAAADGSEPAARAGRGGARAVRVDVKLPRQDALVLEGVRIGPEADPEPLLGGRLLLMDVVDAEQEIPVDGWIAVAYVGKEQAAQFHQENQGSGPKTYPKALVQQMRRALFLGASALLLLILNHSVVRELDISQLLLRPVIVLHYSSNVTKLLEALLQSPCSSYGMPSCLWPCSCAQALWFRPSGRHQDRTSRNLEARWEPDCGSSCAHSPWACKTVAILFPQGDLFKRRVVRRLASLKTRRCRLSRAAHSLPEPGMETCAVCLDNFCNKQWLRVLPCKHEFHRDCVDPWLMLQQTCPLCKFNVLGNHYSDD", "length": 352, "header": "tr|A0A9J7KF46-1|A0A9J7HAP5_CRIGR Computationally mapped isoform of RING finger protein 215 OS=Cricetulus griseus OX=10029 GN=Rnf215 PE=4 SV=1 CANONICAL=A0A9J7HAP5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KF46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KF46" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KF46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KF46" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759166", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759166", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAP5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAP5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ 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annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306037", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306037" } ] }, { "annotation": "May play a role in Cajal bodies formation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MX40", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MX40#function" }, { "database": "UniProtKB", "id": "ARBA00003199", "url": "https://www.uniprot.org/uniprotkb/ARBA00003199#function" }, { "database": "UniProtKB", "id": "A0A9J7H6X1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6X1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6X1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6X1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6X1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6X1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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homolog subfamily B member 6", "type": "recommended", "evidence": [ { "id": "A0A9J7H5T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T8/entry#names_and_taxonomy" } ] }, { "name": "Heat shock protein J2", "type": "synonym", "evidence": [ { "id": "A0A9J7H5T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T8/entry#names_and_taxonomy" } ] }, { "name": "MRJ", "type": "synonym", "evidence": [ { "id": "A0A9J7H5T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T8/entry#names_and_taxonomy" } ] }, { "name": "dnaJ homolog subfamily B member 6 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_035304838", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304838" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304838", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304838" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5T8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100758507", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T8", "locus": {} } ], "crossref": [ { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758507", "url": "https://www.ncbi.nlm.nih.gov/gene/100758507", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758507", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758507", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "APRHFPW", "url": "https://omabrowser.org/oma/group/APRHFPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MXG3", "url": "https://www.orthodb.org/?gene=A0A8C2MXG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MY47", "url": "https://www.orthodb.org/?gene=A0A8C2MY47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GIN0", "url": "https://www.orthodb.org/?gene=A0A9J7GIN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H5T8", "url": "https://www.orthodb.org/?gene=A0A9J7H5T8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45168", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45168", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45168:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45168:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304838", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304838", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MXG3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MXG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MXG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MY47", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MY47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MY47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GIN0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GIN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5T8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K937", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K937", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K937-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K937-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNSGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFDDFFGNRRGSRGNRNRGTGSFFSAFSGFPSFGGGFPAFDTGFTSFGSLGHGGLTSFSSASFGGGGMGNFKSISTSTKIVNGKKITTKRIVENGQERVEVEEDGQLKSLTINGVADENALAEECQRRGQHIPALAHHGPAPATVRVPSPARPPAPSPAPTSAPSSAPSVSTRPQKPPRPAPMAKLVSKSNWEDQEQDRQRVPGNWDAPMTSAGVQKGAGVKHPQSDFSSDSGQRQQKSGLCCCILT", "length": 364, "header": "tr|A0A9J7H5T8-1|A0A9J7H5T8_CRIGR Isoform 1 of DnaJ homolog subfamily B member 6 OS=Cricetulus griseus OX=10029 GN=LOC100758507 PE=4 SV=1 CANONICAL=A0A9J7H5T8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MXG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T8/entry#A0A8C2MXG3-1", "sequence": { "sequence": "MVDYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNSGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFGLLGDFHFQAVRIFAQEKKLLHGYYVYEVTVQPAGGFEEVASEDLEPSEELDQPCFEESVEDALSDEHSEVLDVISSEELDLSEDESSEGCSWGQGGLLSEDLDLVSSEEEASLGDAEELSEEYEELLSEEEHSGPEPEALLVQQ", "length": 260, "header": "tr|A0A8C2MXG3-1|A0A9J7H5T8_CRIGR Computationally mapped isoform of DnaJ homolog subfamily B member 6 OS=Cricetulus griseus OX=10029 GN=LOC100758507 PE=4 SV=1 CANONICAL=A0A9J7H5T8-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MY47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T8/entry#A0A8C2MY47-1", "sequence": { "sequence": "MVDYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNSGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFDDFFGNRRGSRGNRNRGTGSFFSAFSGFPSFGGGFPAFDTGFTSFGSLGHGGLTSFSSASFGGGGMGNFKSISTSTKIVNGKKITTKRIVENGQERVEVEEDGQLKSLTINGVADENALAEECQRRGQHIPALAHHGPAPATVRVPSPARPPAPSPAPTSAPSSAPSVSTRPQKPPRPAPMAKLVSKSNWEDQEQDRQRVPGNWDAPMTSAGLKEGGKRKKQKQKEDSKKKKSTKGNR", "length": 357, "header": "tr|A0A8C2MY47-1|A0A9J7H5T8_CRIGR Computationally mapped isoform of DnaJ homolog subfamily B member 6 OS=Cricetulus griseus OX=10029 GN=LOC100758507 PE=4 SV=1 CANONICAL=A0A9J7H5T8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GIN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T8/entry#A0A9J7GIN0-1", "sequence": { "sequence": "MVDYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNSGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFDPFDDFFGNRRGSRGNRNRGTGSFFSAFSGFPSFGGGFPAFDTGFTSFGSLGHGGLTSFSSASFGGGGMGNFKSISTSTKIVNGKKITTKRIVENGQERVEVEEDGQLKSLTINGVADENALAEECQRRGQHIPALAHHGPAPATVRVPSPARPPAPSPAPTSAPSSAPSVSTRPQKPPRPAPMAKLVSKSNWEDQEQDRQRVPGNWDAPMTSAGLKEGGKRKKQKQKEDSKKKKSTKGNR", "length": 356, "header": "tr|A0A9J7GIN0-1|A0A9J7GIN0_CRIGR Computationally mapped isoform of DnaJ homolog subfamily B member 6 OS=Cricetulus griseus OX=10029 GN=LOC100758507 PE=4 SV=1 CANONICAL=A0A9J7H5T8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H5T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T8/entry#A0A9J7H5T8-1", "sequence": { "sequence": "MVDYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNSGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFDDFFGNRRGSRGNRNRGTGSFFSAFSGFPSFGGGFPAFDTGFTSFGSLGHGGLTSFSSASFGGGGMGNFKSISTSTKIVNGKKITTKRIVENGQERVEVEEDGQLKSLTINGVADENALAEECQRRGQHIPALAHHGPAPATVRVPSPARPPAPSPAPTSAPSSAPSVSTRPQKPPRPAPMAKLVSKSNWEDQEQDRQRVPGNWDAPMTSAGVQKGAGVKHPQSDFSSDSGQRQQKSGLCCCILT", "length": 364, "header": "tr|A0A9J7H5T8-1|A0A9J7H5T8_CRIGR Isoform 1 of DnaJ homolog subfamily B member 6 OS=Cricetulus griseus OX=10029 GN=LOC100758507 PE=4 SV=1 CANONICAL=A0A9J7H5T8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K937-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T8/entry#A0A9J7K937-1", "sequence": { "sequence": "MVDYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNSGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFDDFFGNRRGSRGNRNRGTGSFFSAFSGFPSFGGGFPAFDTGFTSFGSLGHGGLTSFSSASFGGGGMGNFKSISTSTKIVNGKKITTKRIVENGQERVEVEEDGQLKSLTINDRCSIEGGNDRGRTGGNQGQRIQGSRVVVIPSILLLSLSRGLASWQAWKETLSSCRPHSWVTSS", "length": 294, "header": "tr|A0A9J7K937-1|A0A9J7H5T8_CRIGR Computationally mapped isoform of DnaJ homolog subfamily B member 6 OS=Cricetulus griseus OX=10029 GN=LOC100758507 PE=4 SV=1 CANONICAL=A0A9J7H5T8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K937", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K937" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K937", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K937" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758507", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758507", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A5H2-1", "protein_name": "DnaJ heat shock protein family (Hsp40) member B6", "gene_name": "DNAJB6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVDYYEVLGVQKHASAEDIKKAYHKLALKWHPDKNPENKEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGSHHDNPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFEDFFGGRRGPRGSRSRAGGSFLSAFGGFPAFGNAFPSFDTGFTSFGSLGHGGLTSFSSTSFGGSGMGNFKSVSTSTKIVNGRKITTKRIVENGQERVEVEEDGQLRSLTINGEANEEAFAEECRRRGQHALPFQPTNTRLLKPHKPASSPRYAYHYNSDEVEEQEKSRVASSLETPFYLSGVQNHVDEKCAKKDSSASPKGKNKSQARGCCCVT", "length": 333 }, "evidence": [ { "id": "A0A9J7H5T8", "url": "https://omabrowser.org/oma/group/A0A9J7H5T8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O54946-1", "protein_name": "DnaJ homolog subfamily B member 6", "gene_name": "Dnajb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNGGGGGGGIHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFDDFFGNRRGPRGNRSRGAGSFFSTFSGFPSFGSGFPAFDTGFTPFGSLGHGGLTSFSSTSFGGSGMGNFKSISTSTKIVNGKKITTKRIVENGQERVEVEEDGQLKSLTINGVADENALAEECQRRGQPTPALAPGPAPAPVRVPSQARPLAPTPAPTPAPTPAPAPAQTPAPSVSTRPQKPPRPAPTAKLGSKSNWEDDEQDRQRVPGNWDAPMTSAGLKEGGKRKKQKQKEDLKKKKSTKGNH", "length": 365 }, "evidence": [ { "id": "A0A9J7H5T8", "url": "https://omabrowser.org/oma/group/A0A9J7H5T8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O75190-1", "protein_name": "DnaJ homolog subfamily B member 6", "gene_name": "DNAJB6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVDYYEVLGVQRHASPEDIKKAYRKLALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNGGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFEDFFGNRRGPRGSRSRGTGSFFSAFSGFPSFGSGFSSFDTGFTSFGSLGHGGLTSFSSTSFGGSGMGNFKSISTSTKMVNGRKITTKRIVENGQERVEVEEDGQLKSLTINGVADDDALAEERMRRGQNALPAQPAGLRPPKPPRPASLLRHAPHCLSEEEGEQDRPRAPGPWDPLASAAGLKEGGKRKKQKQREESKKKKSTKGNH", "length": 326 }, "evidence": [ { "id": "A0A9J7H5T8", "url": "https://omabrowser.org/oma/group/A0A9J7H5T8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0III6-1", "protein_name": "DnaJ homolog subfamily B member 6", "gene_name": "DNAJB6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVDYYEVLGVQRHASAEDIKKAYRKLALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDRYGKEGLNGGGGGGSHFDSPFEFGFTFRNPEDVFREFFGGRDPFSFDFFEDPFEDFFGHRRGPRGSRSRGTGSFFSTFSGFPSFGGAFPSFDAGFSSFGSLGHGGLTAFSSSSAFGGSGMGNYKSISTSTKVVNGRKITTKRIVENGQERVEVEEDGQLKSLTINGKEQLLRLDNK", "length": 242 }, "evidence": [ { "id": "A0A9J7H5T8", "url": "https://omabrowser.org/oma/group/A0A9J7H5T8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5T8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T8" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5T8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5T8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H5T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T8" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 69, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H6P4-1", "uniprot_ac": "A0A9J7H6P4", "uniprot_id": "A0A9J7H6P4_CRIGR", "mass": { "chemical_mass": 48692.0, "monoisotopic_mass": 48692.0 }, "refseq": { "ac": "XP_035306095", "name": "NF-kappa-B essential modulator isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306095" }, "gene_names": [ { "name": "Ikbkg", "type": "recommended", "evidence": [ { "id": "A0A9J7H6P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4" } ] }, { "name": "Ikbkg", "type": "synonym", "evidence": [ { "id": "XP_035306095", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306095" } ] } ], "protein_names": [ { "name": "NF-kappa-B essential modulator", "type": "recommended", "evidence": [ { "id": "A0A9J7H6P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4/entry#names_and_taxonomy" } ] }, { "name": "IkB kinase-associated protein 1", "type": "synonym", "evidence": [ { "id": "A0A9J7H6P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4/entry#names_and_taxonomy" } ] }, { "name": "Inhibitor of nuclear factor kappa-B kinase subunit gamma", "type": "synonym", "evidence": [ { "id": "A0A9J7H6P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4/entry#names_and_taxonomy" } ] }, { "name": "NF-kappa-B essential modifier", "type": "synonym", "evidence": [ { "id": "A0A9J7H6P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4/entry#names_and_taxonomy" } ] }, { "name": "NF-kappa-B essential modulator isoform X6", "type": "synonym", "evidence": [ { "id": "XP_035306095", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306095" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306095", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306095" } ] }, { "annotation": "Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin plays a key role in IKK activation by multiple signaling receptor pathways. Can recognize and bind both 'Lys-63'-linked and linear polyubiquitin upon cell stimulation, with a much higher affinity for linear polyubiquitin. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0L5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L5#function" }, { "database": "UniProtKB", "id": "ARBA00094158", "url": "https://www.uniprot.org/uniprotkb/ARBA00094158#function" }, { "database": "UniProtKB", "id": "A0A9J7H6P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4#function" }, { "database": "UniProtKB", "id": "A0A9J7H941", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H941#function" }, { "database": "UniProtKB", "id": "A0A9J7H9Y4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9Y4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ikbkg", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4", "locus": {} } ], "crossref": [ { "id": "A0A9J7H6P4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H6P4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09803", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09803", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759762", "url": "https://www.ncbi.nlm.nih.gov/gene/100759762", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032419", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032419", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759762", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759762", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VAMRKNF", "url": "https://omabrowser.org/oma/group/VAMRKNF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N0L5", "url": "https://www.orthodb.org/?gene=A0A8C2N0L5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H6P4", "url": "https://www.orthodb.org/?gene=A0A9J7H6P4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31553", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31553", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31553:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31553:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11577", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11577", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306095", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306095", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N0L5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N0L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H941", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H941", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H941-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H941-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9Y4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLPCWMSKHLWKNQLSEMVQPSGGPAGDQDMQGEESSLGKPAMLQLPSEQGTPETLQRCLEENQELRDAIRQSNQMLRERCEELLHFQVSQREEKEFLMCKFQEARKLVERLSLEKLDLQRQREQVLKDLEHLKKCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKERQTLEGRMRAVSEQVRQLESEREVLQQQHSVQVDQLRMQNQSVEAALRMERQAASEEKRKLAQLQAAYHQLFQDYDSHIKSSKGMQLEDLRQQLQQAEEALVAKQELIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERHAREKLVEKKELLQEQLEQLQREYSKLKVGCHESARIEDMRKRHVETSQPPLLPAPAHHSFHLALPNQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE", "length": 418, "header": "tr|A0A9J7H6P4-1|A0A9J7H6P4_CRIGR Isoform 1 of NF-kappa-B essential modulator OS=Cricetulus griseus OX=10029 GN=Ikbkg PE=4 SV=1 CANONICAL=A0A9J7H6P4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N0L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4/entry#A0A8C2N0L5-1", "sequence": { "sequence": "MSKHLWKNQLSEMVQPSGGPAGDQDMQGEESSLGKPAMLQLPSEQGTPETLQRCLEENQELRDAIRQSNQMLRERCEELLHFQVSQREEKEFLMCKFQEARKLVERLSLEKLDLQRQREQVLKDLEHLKKCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKERQTLEGRMRAVSEQVRQLESEREVLQQQHSVQVDQLRMQNQSVEAALRMERQAASEEKRKLAQLQAAYHQLFQDYDSHIKSSKGMQLEDLRQQLQQAEEALVAKQELIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERHAREKLVEKKELLQEQLEQLQREYSKLKVGCHESARIEDMRKRHVETSQPPLLPAPAHHSFHLALPNQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE", "length": 412, "header": "tr|A0A8C2N0L5-1|A0A9J7H6P4_CRIGR Computationally mapped isoform of NF-kappa-B essential modulator OS=Cricetulus griseus OX=10029 GN=Ikbkg PE=4 SV=1 CANONICAL=A0A9J7H6P4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H6P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4/entry#A0A9J7H6P4-1", "sequence": { "sequence": "MTLPCWMSKHLWKNQLSEMVQPSGGPAGDQDMQGEESSLGKPAMLQLPSEQGTPETLQRCLEENQELRDAIRQSNQMLRERCEELLHFQVSQREEKEFLMCKFQEARKLVERLSLEKLDLQRQREQVLKDLEHLKKCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKERQTLEGRMRAVSEQVRQLESEREVLQQQHSVQVDQLRMQNQSVEAALRMERQAASEEKRKLAQLQAAYHQLFQDYDSHIKSSKGMQLEDLRQQLQQAEEALVAKQELIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERHAREKLVEKKELLQEQLEQLQREYSKLKVGCHESARIEDMRKRHVETSQPPLLPAPAHHSFHLALPNQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE", "length": 418, "header": "tr|A0A9J7H6P4-1|A0A9J7H6P4_CRIGR Isoform 1 of NF-kappa-B essential modulator OS=Cricetulus griseus OX=10029 GN=Ikbkg PE=4 SV=1 CANONICAL=A0A9J7H6P4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H941-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4/entry#A0A9J7H941-1", "sequence": { "sequence": "MSKHLWKNQLSEMVQPSGGPAGDQDMQGEESSLGKPAMLQLPSEQGTPETLQRCLEENQELRDAIRQSNQMLRERCEELLHFQVSQREEKEFLMCKFQEARKLVERLSLEKLDLQRQREQVLKDLEHLKKCQQMAEDKASVKAQVTSLLGELQESQSRLEAATKERQTLEGRRKLAQLQAAYHQLFQDYDSHIKSSKGMQLEDLRQQLQQAEEALVAKQELIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERHAREKLVEKKELLQEQLEQLQREYSKLKVGCHESARIEDMRKRHVETSQPPLLPAPAHHSFHLALPNQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE", "length": 360, "header": "tr|A0A9J7H941-1|A0A9J7H941_CRIGR Computationally mapped isoform of NF-kappa-B essential modulator OS=Cricetulus griseus OX=10029 GN=Ikbkg PE=4 SV=1 CANONICAL=A0A9J7H6P4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4/entry#A0A9J7H9Y4-1", "sequence": { "sequence": "MSKHLWKNQLSEMVQPSGGPAGDQDMQGEESSLGKPAMLQLPSEQGTPETLQRCLEENQELRDAIRQSNQMLRERCEELLHFQVSQREEKEFLMCKFQEARKLVERLSLEKLDLQRQREQVLKDLEHLKKCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKERQTLEGRRKLAQLQAAYHQLFQDYDSHIKSSKGMQLEDLRQQLQQAEEALVAKQELIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERHAREKLVEKKELLQEQLEQLQREYSKLKVGCHESARIEDMRKRHVETSQPPLLPAPAHHSFHLALPNQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE", "length": 361, "header": "tr|A0A9J7H9Y4-1|A0A9J7H9Y4_CRIGR Computationally mapped isoform of NF-kappa-B essential modulator OS=Cricetulus griseus OX=10029 GN=Ikbkg PE=4 SV=1 CANONICAL=A0A9J7H6P4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0L5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N0L5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0L5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759762", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759762", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A9QT41-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRTPWKSQPCEMVQPSGGPAGDQDVLGEESSLGKPTMLHLPSEQGAPETFQRCLEENQELRDAIRQSNQMLRERCEELQRFQGSQREEKEFLMQKFCEARRLVERLSLEKLELRRQREQALQEVELLKTCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKERQALESRVRATSEQVRQLENEREALQQQHSVQVDQLRLQSQSMEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIKSSVVSSERNRGLQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREQLAERKELLQEQLEQLQREYSRLKTSCQESARIEDMRKRHVEVSQPTLPPAPAHHSFHPALPSQRRSPPEEPPNFCCPKCQYQAPDMDTLQIHVMECIE", "length": 419 }, "evidence": [ { "id": "A0A9J7H6P4", "url": "https://omabrowser.org/oma/group/A0A9J7H6P4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O88522-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "Ikbkg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNKHPWKNQLSEMVQPSGGPAEDQDMLGEESSLGKPAMLHLPSEQGTPETLQRCLEENQELRDAIRQSNQMLRERCEELLHFQVSQREEKEFLMCKFQEARKLVERLSLEKLDLRSQREQALKELEQLKKCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKDRQALEGRIRAVSEQVRQLESEREVLQQQHSVQVDQLRMQNQSVEAALRMERQAASEEKRKLAQLQAAYHQLFQDYDSHIKSSKGMQLEDLRQQLQQAEEALVAKQELIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERHAREKLVEKKEYLQEQLEQLQREFNKLKVGCHESARIEDMRKRHVETPQPPLLPAPAHHSFHLALSNQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE", "length": 412 }, "evidence": [ { "id": "A0A9J7H6P4", "url": "https://omabrowser.org/oma/group/A0A9J7H6P4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6TMG5-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "Ikbkg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRHLWKNQLSEMVQPSGGPAEDQDMLGEESSLGKPAMLHLPSEQGTPETLQRCLEENQELRDAIRQSNQMLRERCEELLHFQVSQREEKEFLMCKFQEARKLVERLSLEKLDLRRQREQALEDLEHLKKCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKERQTLEGRIRAVSEQVRQLESEREVLQQQHSVQVDQLRMQNQSVEAALRMERQAASEEKRKLAQLQAAYHQLFQDYDSHIKSSKGMQLEDLRQQLQQAEEALVAKQELIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERHAREKLVERKELLQEQLEQLQREFNKLKVGCHESARIEDMRKRHVETSQPPLLPAPAHHSFHLALSNQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE", "length": 412 }, "evidence": [ { "id": "A0A9J7H6P4", "url": "https://omabrowser.org/oma/group/A0A9J7H6P4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q95KU9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRPPWKSPLCEMVQPSGSPAGDQDMLGEESSLGKPAMLHVPSEQGTPETFQRCLEENQELRDAIRQSNQMLRERCEELQHFQGNQREEKAFLMQKFQEARDLVVRLSLEKRELRQQREQALKEVERLKTCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKERQALESRARVASEKARQLESEREALEQRHSVQVDQLVLQNESMEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHMKSSMVSSERNRGLQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKEFLQEQLEQLQREYSRLKTSCQESARIEDMRKRHVEVSQPPLAPGPAHHSFHLNPSSQRRSPPDEPPKFCCPKCQYQAPDIDTLQIHVMECIE", "length": 419 }, "evidence": [ { "id": "A0A9J7H6P4", "url": "https://omabrowser.org/oma/group/A0A9J7H6P4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNRHLWKSQLCEMVQPSGGPAADQDVLGEESPLGKPAMLHLPSEQGAPETLQRCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARKLVERLGLEKLDLKRQKEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQALEGRARAASEQARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIKSSVVGSERKRGMQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLKASCQESARIEDMRKRHVEVSQAPLPPAPAYLSSPLALPSQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE", "length": 419 }, "evidence": [ { "id": "A0A9J7H6P4", "url": "https://omabrowser.org/oma/group/A0A9J7H6P4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4" } ], "pmid": "" }, { "name": "IkappaB kinase complex", "id": "GO:0008385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008385", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4" } ], "pmid": "" }, { "name": "K63-linked polyubiquitin modification-dependent protein binding", "id": "GO:0070530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070530", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H6P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P4" }, { "id": "PS51801", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51801" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCHC NOA-type", "eco_id": "ECO_0000259", "start_pos": 388, "end_pos": 418, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 212, "end_pos": 214 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"A0A9J7H9E2_CRIGR", "mass": { "chemical_mass": 43847.0, "monoisotopic_mass": 43847.0 }, "refseq": { "ac": "XP_035307557", "name": "UDP-GalNAc:beta-1, 3-N-acetylgalactosaminyltransferase 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307557" }, "gene_names": [ { "name": "B3galnt1", "type": "recommended", "evidence": [ { "id": "A0A9J7H9E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2" } ] }, { "name": "B3galnt1", "type": "synonym", "evidence": [ { "id": "XP_035307557", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307557" } ] } ], "protein_names": [ { "name": "Hexosyltransferase", "type": "recommended", "evidence": [ { "id": "A0A9J7H9E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "A0A9J7H9E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2/entry#names_and_taxonomy" } ] }, { "name": "UDP-GalNAc:beta-1, 3-N-acetylgalactosaminyltransferase 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035307557", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307557" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307557", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307557" } ] }, { "annotation": "Transfers N-acetylgalactosamine onto globotriaosylceramide. Plays a critical role in preimplantation stage embryonic development.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KB83", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB83#function" }, { "database": "UniProtKB", "id": "ARBA00045577", "url": "https://www.uniprot.org/uniprotkb/ARBA00045577#function" }, { "database": "UniProtKB", "id": "A0A8C2QCT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCT1#function" }, { "database": "UniProtKB", "id": "A0A9J7H9E2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2#function" }, { "database": "UniProtKB", "id": "A0A9J7HA30", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA30#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9E2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "B3galnt1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2", "locus": {} } ], "crossref": [ { "id": "100756438", "url": "https://www.ncbi.nlm.nih.gov/gene/100756438", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756438", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756438", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DICKYRH", "url": "https://omabrowser.org/oma/group/DICKYRH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QCT1", "url": "https://www.orthodb.org/?gene=A0A8C2QCT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H9E2", "url": "https://www.orthodb.org/?gene=A0A9J7H9E2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11214", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11214", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11214:SF153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11214:SF153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01762", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01762", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307557", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307557", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "22252", "url": "https://www.rhea-db.org/rhea/22252", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QCT1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QCT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9E2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA30", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA30-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KB83", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KB83-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPAVLTTLLNRMSLRSLKWSLLLLSLLSFLVMWYLSLPHYNVIERVNWMYFYEYEPIYRQDFRFTLREHSNCSHQNPFLVILVTSRPSDVKARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEKEDKMLALSLEDEHLLYGDIIRQDFLDTYNNLTLKTIMAFRWVIEFCPNAKYVMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFFHKNHISYQEYPFKVFPPYCSGLGYIMSSDLVPRIYEMMSHVKPIKFEDVYVGICLNLLKVNIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITYWQCWPFLVELFLREERGVLVPRFQGTQLSLSPRGDEEQVIPLLLMMIWY", "length": 368, "header": "tr|A0A9J7H9E2-1|A0A9J7H9E2_CRIGR Isoform 1 of Hexosyltransferase OS=Cricetulus griseus OX=10029 GN=B3galnt1 PE=3 SV=1 CANONICAL=A0A9J7H9E2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QCT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2/entry#A0A8C2QCT1-1", "sequence": { "sequence": "MAPAVLTTLLNRMSLRSLKWSLLLLSLLSFLVMWYLSLPHYNVIERVNWMYFYEYEPIYRQDFRFTLREHSNCSHQNPFLVILVTSRPSDVKARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEKEDKMLALSLEDEHLLYGDIIRQDFLDTYNNLTLKTIMAFRWVIEFCPNAKYVMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFFHKNHISYQEYPFKVFPPYCSGLGYIMSSDLVPRIYEMMSHVKPIKFEDVYVGICLNLLKVNIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITYWQVMLRNTTCHY", "length": 331, "header": "tr|A0A8C2QCT1-1|A0A9J7H9E2_CRIGR Computationally mapped isoform of Hexosyltransferase OS=Cricetulus griseus OX=10029 GN=B3galnt1 PE=3 SV=1 CANONICAL=A0A9J7H9E2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2/entry#A0A9J7H9E2-1", "sequence": { "sequence": "MAPAVLTTLLNRMSLRSLKWSLLLLSLLSFLVMWYLSLPHYNVIERVNWMYFYEYEPIYRQDFRFTLREHSNCSHQNPFLVILVTSRPSDVKARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEKEDKMLALSLEDEHLLYGDIIRQDFLDTYNNLTLKTIMAFRWVIEFCPNAKYVMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFFHKNHISYQEYPFKVFPPYCSGLGYIMSSDLVPRIYEMMSHVKPIKFEDVYVGICLNLLKVNIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITYWQCWPFLVELFLREERGVLVPRFQGTQLSLSPRGDEEQVIPLLLMMIWY", "length": 368, "header": "tr|A0A9J7H9E2-1|A0A9J7H9E2_CRIGR Isoform 1 of Hexosyltransferase OS=Cricetulus griseus OX=10029 GN=B3galnt1 PE=3 SV=1 CANONICAL=A0A9J7H9E2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HA30-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2/entry#A0A9J7HA30-1", "sequence": { "sequence": "MAPAVLTTLLNRMSLRSLKWSLLLLSLLSFLVMWYLSLPHYNVIERVNWMYFYEYEPIYRQDFRFTLREHSNCSHQNPFLVILVTSRPSDVKARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEKEDKMLALSLEDEHLLYGDIIRQDFLDTYNNLTLKTIMAFRWVIEFCPNAKYVMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFFHKNHISYQEYPFKVFPPYCSGLGYIMSSDLVPRIYEMMSHVKPIKFEDVYVGICLNLLKVNIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITYWQCWPFLVELFLREERGVLVPRFQGTQLSLSPRGDEEQQPLQ", "length": 361, "header": "tr|A0A9J7HA30-1|A0A9J7HA30_CRIGR Computationally mapped isoform of Hexosyltransferase OS=Cricetulus griseus OX=10029 GN=B3galnt1 PE=3 SV=1 CANONICAL=A0A9J7H9E2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KB83-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2/entry#A0A9J7KB83-1", "sequence": { "sequence": "MAPAVLTTLLNRMSLRSLKWSLLLLSLLSFLVMWYLSLPHYNVIERVNWMYFYEYEPIYRQDFRFTLREHSNCSHQNPFLVILVTSRPSDVKARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEKEDKMLALSLEDEHLLYGDIIRQDFLDTYNNLTLKTIMAFRWVIEFCPNAKYVMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFFHKNHISYQEYPFKVFPPYCSGLGYIMSSDLVPRIYEMMSHVKPIKFEDVYVGICLNLLKVNIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITYWQNLGMIENSRQYIS", "length": 334, "header": "tr|A0A9J7KB83-1|A0A9J7H9E2_CRIGR Computationally mapped isoform of Hexosyltransferase OS=Cricetulus griseus OX=10029 GN=B3galnt1 PE=3 SV=1 CANONICAL=A0A9J7H9E2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KB83", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB83" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KB83", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB83" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756438", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756438", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X4B7-1", "protein_name": "Hexosyltransferase", "gene_name": "B3GALNT1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHMIPLKWIFFFLLVFSVVTMWYITFSSNVVVEHVNSMYFYEYEPVYKQAYLFTSHQHLKCKDINPFLVILVSSRPKDVKSRQAIRITWGSNSFWWGHRVLTLFLLGQEAETEDNSAALSVEDEIILYGDIIRQDFMDTYNNLTLKTIMAFRWVAEFCSNARFIMKTDTDVFINTGNLVKFLLKLNSSESIFTGYPLISNVAYRGFYQKTYISYDEYPFKFYPPYCSGMGYVLDGKLALRIYELMGHIKPIKFEDVYVGICLNILKVNISIQEGNQQFFIDKIDFDICKYRRLIAVHGITPSEMIRFWKDLSSIISVTCL", "length": 320 }, "evidence": [ { "id": "A0A9J7H9E2", "url": "https://omabrowser.org/oma/group/A0A9J7H9E2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O75752-1", "protein_name": "UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1", "gene_name": "B3GALNT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASALWTVLPSRMSLRSLKWSLLLLSLLSFFVMWYLSLPHYNVIERVNWMYFYEYEPIYRQDFHFTLREHSNCSHQNPFLVILVTSHPSDVKARQAIRVTWGEKKSWWGYEVLTFFLLGQEAEKEDKMLALSLEDEHLLYGDIIRQDFLDTYNNLTLKTIMAFRWVTEFCPNAKYVMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFYQKTHISYQEYPFKVFPPYCSGLGYIMSRDLVPRIYEMMGHVKPIKFEDVYVGICLNLLKVNIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITFWQVMLRNTTCHY", "length": 331 }, "evidence": [ { "id": "A0A9J7H9E2", "url": "https://omabrowser.org/oma/group/A0A9J7H9E2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6AY39-1", "protein_name": "UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1", "gene_name": "B3galnt1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPAVLTAIPNRMSLRSLKWSLLLLSLLSFLVIWYLSLPHYNVIERVNWMYFYEYEPIYRQDFQFTLREHSNCSQQNPFLVILVTSRPSDVKARQAIRVTWGEKKTWWGHEVLTFFLLGQEAEREDKVLALSLEDEHALYGDIIRQDFLDTYNNLTLKTIMAFRWVIEFCPNAKYVMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIENYSYRGFFHKNHISYQEYPFKVFPPYCSGLGYIMSGDLVPKIYEMMGHVKPIKFEDVYVGICLNLLKVDIHIPEDTNLFFLFRIHLDVCQLRRVIAAHGFSSKEIITFWQVMLRNTTCHY", "length": 331 }, "evidence": [ { "id": "A0A9J7H9E2", "url": "https://omabrowser.org/oma/group/A0A9J7H9E2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q864U6-1", "protein_name": "UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1", "gene_name": "B3GALNT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPALPITLPSKMSLRSLKWSLLLLSLLSFLVMWYLSLPHYNVIERVNWMYFYEYEPIYRQDFHFTLREHSNCSHQNPFLVILVTSHPADVKARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEREDKVLALSLEDEHLLYGDIIRQDFLDTYNNLTLKTIMAFRWVTEFCPNARYIMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFYQKTHISYQEYPFKVFPPYCSGLGYIMSRDLVPRIYEMMSHVKPIKFEDVYVGICLNLLKVDIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITFWQVMLRNTTCHY", "length": 331 }, "evidence": [ { "id": "A0A9J7H9E2", "url": "https://omabrowser.org/oma/group/A0A9J7H9E2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q920V1-1", "protein_name": "UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1", "gene_name": "B3galnt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPAVLTALPNRMSLRSLKWSLLLLSLLSFLVIWYLSLPHYNVIERVNWMYFYEYEPIYRQDFRFTLREHSNCSHQNPFLVILVTSRPSDVKARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEREDKTLALSLEDEHVLYGDIIRQDFLDTYNNLTLKTIMAFRWVMEFCPNAKYIMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFFHKNHISYQEYPFKVFPPYCSGLGYIMSGDLVPRVYEMMSHVKPIKFEDVYVGICLNLLKVDIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITFWQVMLRNTTCHY", "length": 331 }, "evidence": [ { "id": "A0A9J7H9E2", "url": "https://omabrowser.org/oma/group/A0A9J7H9E2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9E2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9E2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2" } ], "pmid": "" }, { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9E2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity", "id": "GO:0008499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008499", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9E2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2" } ], "pmid": "" }, { "name": "galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity", "id": "GO:0047273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047273", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9E2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22252", "name": "", "equation": "a globoside Gb3Cer (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a globoside Gb4Cer (d18:1(4E)) + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7H9E2-1" ], "evidence": [ { "id": "22252", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22252" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7H9E2", "gene_name": "B3galnt1", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A9J7H9E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9E2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 198, "end_pos": 200 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HTH3", "url": "https://www.uniprot.org/uniprotkb/A0A061HTH3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HA08-1", "uniprot_ac": "A0A9J7HA08", "uniprot_id": "A0A9J7HA08_CRIGR", "mass": { "chemical_mass": 27917.0, "monoisotopic_mass": 27917.0 }, "refseq": { "ac": "XP_035307534", "name": "clarin-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307534" }, "gene_names": [ { "name": "Clrn1", "type": "recommended", "evidence": [ { "id": "A0A9J7HA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08" } ] }, { "name": "Clrn1", "type": "synonym", "evidence": [ { "id": "XP_035307534", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307534" } ] } ], "protein_names": [ { "name": "Clarin-1", "type": "recommended", "evidence": [ { "id": "A0A9J7HA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08/entry#names_and_taxonomy" } ] }, { "name": "Usher syndrome type-3 protein homolog", "type": "synonym", "evidence": [ { "id": "A0A9J7HA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08/entry#names_and_taxonomy" } ] }, { "name": "clarin-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035307534", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307534" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307534", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307534" } ] }, { "annotation": "May have a role in the excitatory ribbon synapse junctions between hair cells and cochlear ganglion cells and presumably also in analogous synapses within the retina.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08#function" }, { "database": "UniProtKB", "id": "ARBA00056555", "url": "https://www.uniprot.org/uniprotkb/ARBA00056555#function" }, { "database": "UniProtKB", "id": "A0A8C2LIG4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIG4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Clrn1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08", "locus": {} } ], "crossref": [ { "id": "A0A9J7HA08", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HA08", "database": "AlphaFoldDB", "categories": [] }, { "id": "100768820", "url": "https://www.ncbi.nlm.nih.gov/gene/100768820", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768820", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768820", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IIFCTAG", "url": "https://omabrowser.org/oma/group/IIFCTAG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LIG4", "url": "https://www.orthodb.org/?gene=A0A8C2LIG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7HA08", "url": "https://www.orthodb.org/?gene=A0A9J7HA08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31548", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31548", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31548:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31548:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25807", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25807", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307534", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307534", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LIG4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LIG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LK81", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LK81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA08-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KB75", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KB75-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPNQQKKVIFCMAGVLSFLCALGVVTAVGTPLWIKATILCKTGALLVNASGEELSKFMGEMQYGLFHGEGIRQCGLGARPFRFSCKRLKDRFTLYEDKVEKSVFPDLLQAIPVSIHVNIILFSMILVVLTMVGTAFFMYNAFGKPFETLHGPLGLYLVSFISGSCGCLVMILFASEVKIHHLSEKIANFKEGTYAYKTQNENYTTSFWVVFICFFVHFLNGLLIRLAGFQFPFAKSKDTETTNVAADLMY", "length": 250, "header": "tr|A0A9J7HA08-1|A0A9J7HA08_CRIGR Isoform 1 of Clarin-1 OS=Cricetulus griseus OX=10029 GN=Clrn1 PE=3 SV=1 CANONICAL=A0A9J7HA08-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LIG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08/entry#A0A8C2LIG4-1", "sequence": { "sequence": "MPNQQKKVIFCMAGVLSFLCALGVVTAVGTPLWIKATILCKTGALLVNASGEELSKFMGEMQYGLFHGEGIRQCGLGARPFRFSFFPDLLQAIPVSIHVNIILFSMILVVLTMVGTAFFMYNAFGKPFETLHGPLGLYLVSFISGSCGCLVMILFASEVKIHHLSEKIANFKEGTYAYKTQNENYTTSFWVVFICFFVHFLNGLLIRLAGFQFPFAKSKDTETTNVAADLMY", "length": 232, "header": "tr|A0A8C2LIG4-1|A0A8C2LIG4_CRIGR Computationally mapped isoform of Clarin-1 OS=Cricetulus griseus OX=10029 GN=Clrn1 PE=3 SV=1 CANONICAL=A0A9J7HA08-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LK81-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08/entry#A0A8C2LK81-1", "sequence": { "sequence": "MPNQQKKVIFCMAGVLSFLCALGVVTAVGTPLWIKATILCKTGALLVNASGEELSKFMGEMQYGLFHGEGIRQCGLGARPFRFSCSCGCLVMILFASEVKIHHLSEKIANFKEGTYAYKTQNENYTTSFWVVFICFFVHFLNGLLIRLAGFQFPFAKSKDTETTNVAADLMY", "length": 172, "header": "tr|A0A8C2LK81-1|A0A9J7HA08_CRIGR Computationally mapped isoform of Clarin-1 OS=Cricetulus griseus OX=10029 GN=Clrn1 PE=3 SV=1 CANONICAL=A0A9J7HA08-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HA08-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08/entry#A0A9J7HA08-1", "sequence": { "sequence": "MPNQQKKVIFCMAGVLSFLCALGVVTAVGTPLWIKATILCKTGALLVNASGEELSKFMGEMQYGLFHGEGIRQCGLGARPFRFSCKRLKDRFTLYEDKVEKSVFPDLLQAIPVSIHVNIILFSMILVVLTMVGTAFFMYNAFGKPFETLHGPLGLYLVSFISGSCGCLVMILFASEVKIHHLSEKIANFKEGTYAYKTQNENYTTSFWVVFICFFVHFLNGLLIRLAGFQFPFAKSKDTETTNVAADLMY", "length": 250, "header": "tr|A0A9J7HA08-1|A0A9J7HA08_CRIGR Isoform 1 of Clarin-1 OS=Cricetulus griseus OX=10029 GN=Clrn1 PE=3 SV=1 CANONICAL=A0A9J7HA08-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KB75-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08/entry#A0A9J7KB75-1", "sequence": { "sequence": "MPNQQKKVIFCMAGVLSFLCALGVVTAVGTPLWIKATILCKTGALLVNASGEELSKFMGEMQYGLFHGEGIRQCGLGARPFRFSFFPDLLQAIPVSIHVNIILFSMILVVLTMVGTAFFMYNAFGKPFETLHGPLGLYLVSFISVSLFRTPAERHSSKGSCGCLVMILFASEVKIHHLSEKIANFKEGTYAYKTQNENYTTSFWVVFICFFVHFLNGLLIRLAGFQFPFAKSKDTETTNVAADLMY", "length": 246, "header": "tr|A0A9J7KB75-1|A0A9J7HA08_CRIGR Computationally mapped isoform of Clarin-1 OS=Cricetulus griseus OX=10029 GN=Clrn1 PE=3 SV=1 CANONICAL=A0A9J7HA08-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LK81", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK81" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LK81", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK81" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768820", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768820", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B3L8-1", "protein_name": "Clarin-1", "gene_name": "CLRN1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPNQQKKVIFCMAGVLSFLCALGVVTALGTPLWIKATFFCKTGALLVNASGQELDKFMGEMQYGLFHGEGVRQCGLGARPFRFSFFPDLLKAIPVSIHVNVILFSTILIVLTLVGTAFFMYNAFGKPFETLHGPLGLYLLSFISGSCGCLVMILFASEVKIHHLSEKIANYKEGTYAYKTQSEKYTTSFWVVFICFFVHFLNGLLIRLAGFQFPFAKSKDTQTTNVAADLMY", "length": 232 }, "evidence": [ { "id": "A0A9J7HA08", "url": "https://omabrowser.org/oma/group/A0A9J7HA08/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BDG3-1", "protein_name": "Clarin-1", "gene_name": "CLRN1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPSQQKKVIFCMAGMLSFMCALGVVTALGTPLWIKATFLCKTGALLVNASGQELDKFMGEMQYGLFHGEGVRQCGLGKRPFRFSFFLDLLKAIPVSIHVNVILFSTILIVLTLVGTAFFMYNAFGKPFETLHGPLGLYLLSFISGSCGCLVMILFASEVKLHHLSEKIANYKEGTYAYKTQSEKYTASFWVVFICFFVHFLNGLLIRLAGFQFPFAKSKDTETANVAADLMY", "length": 232 }, "evidence": [ { "id": "A0A9J7HA08", "url": "https://omabrowser.org/oma/group/A0A9J7HA08/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P58418-3", "protein_name": "Clarin-1", "gene_name": "CLRN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSQQKKIIFCMAGVFSFACALGVVTALGTPLWIKATVLCKTGALLVNASGQELDKFMGEMQYGLFHGEGVRQCGLGARPFRFSFFPDLLKAIPVSIHVNVILFSAILIVLTMVGTAFFMYNAFGKPFETLHGPLGLYLLSFISGSCGCLVMILFASEVKIHHLSEKIANYKEGTYVYKTQSEKYTTSFWVIFFCFFVHFLNGLLIRLAGFQFPFAKSKDAETTNVAADLMY", "length": 232 }, "evidence": [ { "id": "A0A9J7HA08", "url": "https://omabrowser.org/oma/group/A0A9J7HA08/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CJ58-1", "protein_name": "Clarin-1", "gene_name": "Clrn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSQQKKIIFCMAGVFSFACALGVVTALGTPLWIKATVLCKTGALLVNASGQELDKFMGEMQYGLFHGEGVRQCGLGARPFRFSFFPDLLKAIPVSIHVNIILFSMILVVLTMVGTAFFMYNAFGKPFESLHGPLGLYLVSFISGSCGCLVMILFASEVKIHRLSEKIANFKEGTYAYKTQNENYTTSFWVVFICFFVHFLNGLLIRLAGFQFPFTKSKETETTNVASDLMY", "length": 232 }, "evidence": [ { "id": "A0A9J7HA08", "url": "https://omabrowser.org/oma/group/A0A9J7HA08/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K445-1", "protein_name": "Clarin-1", "gene_name": "Clrn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSQQKKIIFCMAGVLSFLCALGVVTAVGTPLWVKATILCKTGALLVNASGKELDKFMGEMQYGLFHGEGVRQCGLGARPFRFSFFPDLVQAIPVSIHINIILFSMILVVLTMVGTAFFMYNAFGKPFETLHGPLGLYLVSFISGSCGCLVMILFASEVKVHRLSEKIANFKEGTYAYRTQNENYTTSFWVVFICFFVHFLNGLLIRLAGFQFPFTKSKETETTNVASDLMY", "length": 232 }, "evidence": [ { "id": "A0A9J7HA08", "url": "https://omabrowser.org/oma/group/A0A9J7HA08/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08" } ], "pmid": "" }, { "name": "actin-based cell projection", "id": "GO:0098858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098858", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08" } ], "pmid": "" }, { "name": "basal part of cell", "id": "GO:0045178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045178", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA08" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": 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"UniProtKB", "id": "A0A9J7H736", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H736" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Vit", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H736", "locus": {} } ], "crossref": [ { "id": "A0A9J7H736", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H736", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01472", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01472", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766029", "url": "https://www.ncbi.nlm.nih.gov/gene/100766029", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766029", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766029", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H736", "url": "https://www.orthodb.org/?gene=A0A9J7H736", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303778", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303778", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H402", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H402", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H402-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H402-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H736", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H736", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H736-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H736-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K0L9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K0L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0L9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K875", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K875", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K875-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K875-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSGHLSVSASKLVLEIVLLVTGIHSNKEVAKKIKRPKFAVPQINCDVKAGKIINSEFMVKCPAGCQDPKYHVYGTGVYASYSSVCGAAVHSGVLDNSGGKILVQKVAGQSGYKGSYANGIQSLSLPRWRESFIISESKPQKGVTYPSTLTYSSAKNPAAQAGEATKAYEKPSITGTTTQPVTLTQALAIPVAEATHRTTSKPLAASVTSSPRPQPVGHRSQEMGLWSPTSYAGSQHSPGSHPGRVPEKPTGAAFQESWGSLESVPLGEMGVWKPGPVLLDSGFVPKEELSTQSSEPVSQGDPNCKVDLSFLIDGSTNIGKRRFRIQKQFLADVVQALDIGPAGPLVGVVQYGDIPATQFNLKTHVNSQDLKAAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRGGAPNVAVVMVDGWPTDKVEEVSRVARESGINVFFITVEGAAESEKQYVVEPNFSSKAVCRTNGFYSFNVQSWLSLHKTVQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTSNFRTVLQFVANLSKEFEISDTDTRIGAVQYTYEQRLEFGFDKYNSKNDILSAIRRVGYWSGGTSTGAAIQYALEQLFKKSKPNKRKVMILITDGRSYDDVRIPAMAAYRKGVITYAIGIAWAAQDELEVIATHPARDHSFFVDEFDNLYKFVPRIIQNICTEFNSQPRN", "length": 693, "header": "tr|A0A9J7H736-1|A0A9J7H736_CRIGR Isoform 1 of Vitrin OS=Cricetulus griseus OX=10029 GN=Vit PE=4 SV=1 CANONICAL=A0A9J7H736-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H402-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H736/entry#A0A9J7H402-1", "sequence": { "sequence": "MRSGHLSVSASKLVLEIVLLVTGIHSNKEVAKKIKRPKFAVPQINCDVKAGKIINSEFMVKCPAGCQDPKYHVYGTGVYASYSSVCGAAVHSGVLDNSGGKILVQKVAGQSGYKGSYANGIQSLSLPRWRESFIISESKPQKGVTYPSTLTYSSAKNPAAQAGEATKAYEKPSITGTTTQPVTLTQALAIPVAEATHRTTSKPLAASVTSSPRPQPVGHRSQEMGLWSPTSYAGSQHSPGSHPGRVPEKPTGAAFQESWGSLESVPLGFVPKEELSTQSSEPVSQGDPNCKVDLSFLIDGSTNIGKRRFRIQKQFLADVVQALDIGPAGPLVGVVQYGDIPATQFNLKTHVNSQDLKAAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRGGAPNVAVVMVDGWPTDKVEEVSRVARESGINVFFITVEGAAESEKQYVVEPNFSSKAVCRTNGFYSFNVQSWLSLHKTVQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTSNFRTVLQFVANLSKEFEISDTDTRIGAVQYTYEQRLEFGFDKYNSKNDILSAIRRVGYWSGGTSTGAAIQYALEQLFKKSKPNKRKVMILITDGRSYDDVRIPAMAAYRKGVITYAIGIAWAAQDELEVIATHPARDHSFFVDEFDNLYKFVPRIIQNICTEFNSQPRN", "length": 678, "header": "tr|A0A9J7H402-1|A0A9J7H736_CRIGR Computationally mapped isoform of Vitrin OS=Cricetulus griseus OX=10029 GN=Vit PE=4 SV=1 CANONICAL=A0A9J7H736-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H4Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H736/entry#A0A9J7H4Q2-1", "sequence": { "sequence": "MRSGHLSVSASKLVLEIVLLVTGIHSNKEVAKKIKRPKFAVPQINCDVKAGKIINSEFMVKCPAGCQDPKYHVYGTGVYASYSSVCGAAVHSGVLDNSGGKILVQKVAGQSGYKGSYANGIQSLSLPRWRESFIISESKPQKGVTYPSTLTYSSAKNPAAQAGEATKAYEKPSITGTTTQPVTLTQALAIPVAEATHRTTSKPLAASVTSSPRPQPVGHRSQEMGLWSPTSYAGSQHSPGSHPGRVPEKPTGAAFQESWGSLESVPLDCKVDLSFLIDGSTNIGKRRFRIQKQFLADVVQALDIGPAGPLVGVVQYGDIPATQFNLKTHVNSQDLKAAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRGGAPNVAVVMVDGWPTDKVEEVSRVARESGINVFFITVEGAAESEKQYVVEPNFSSKAVCRTNGFYSFNVQSWLSLHKTVQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTSNFRTVLQFVANLSKEFEISDTDTRIGAVQYTYEQRLEFGFDKYNSKNDILSAIRRVGYWSGGTSTGAAIQYALEQLFKKSKPNKRKVMILITDGRSYDDVRIPAMAAYRKGVITYAIGIAWAAQDELEVIATHPARDHSFFVDEFDNLYKFVPRIIQNICTEFNSQPRN", "length": 657, "header": "tr|A0A9J7H4Q2-1|A0A9J7H736_CRIGR Computationally mapped isoform of Vitrin OS=Cricetulus griseus OX=10029 GN=Vit PE=4 SV=1 CANONICAL=A0A9J7H736-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H736-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H736/entry#A0A9J7H736-1", "sequence": { "sequence": "MRSGHLSVSASKLVLEIVLLVTGIHSNKEVAKKIKRPKFAVPQINCDVKAGKIINSEFMVKCPAGCQDPKYHVYGTGVYASYSSVCGAAVHSGVLDNSGGKILVQKVAGQSGYKGSYANGIQSLSLPRWRESFIISESKPQKGVTYPSTLTYSSAKNPAAQAGEATKAYEKPSITGTTTQPVTLTQALAIPVAEATHRTTSKPLAASVTSSPRPQPVGHRSQEMGLWSPTSYAGSQHSPGSHPGRVPEKPTGAAFQESWGSLESVPLGEMGVWKPGPVLLDSGFVPKEELSTQSSEPVSQGDPNCKVDLSFLIDGSTNIGKRRFRIQKQFLADVVQALDIGPAGPLVGVVQYGDIPATQFNLKTHVNSQDLKAAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRGGAPNVAVVMVDGWPTDKVEEVSRVARESGINVFFITVEGAAESEKQYVVEPNFSSKAVCRTNGFYSFNVQSWLSLHKTVQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTSNFRTVLQFVANLSKEFEISDTDTRIGAVQYTYEQRLEFGFDKYNSKNDILSAIRRVGYWSGGTSTGAAIQYALEQLFKKSKPNKRKVMILITDGRSYDDVRIPAMAAYRKGVITYAIGIAWAAQDELEVIATHPARDHSFFVDEFDNLYKFVPRIIQNICTEFNSQPRN", "length": 693, "header": "tr|A0A9J7H736-1|A0A9J7H736_CRIGR Isoform 1 of Vitrin OS=Cricetulus griseus OX=10029 GN=Vit PE=4 SV=1 CANONICAL=A0A9J7H736-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K0L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H736/entry#A0A9J7K0L9-1", "sequence": { "sequence": "MRSGHLSVSASKLVLEIVLLVTGIHSNKEVAKKIKRPKFAVPQINCDVKAGKIINSEFMVKCPAGCQDPKYHVYGTGVYASYSSVCGAAVHSGVLDNSGGKILVQKVAGQSGYKGSYANGIQSLSLPRWRESFIISESKPQKGVTYPSTLTYSSAKNPAAQAGEATKAYEKPSITGTTTQPVTLTQALAIPVAEATHRTTSKPLAASVTSSPRPQPVGHRSQEMGLWSPTSYAGSQHSPGSHPGFVPKEELSTQSSEPVSQGDPNCKVDLSFLIDGSTNIGKRRFRIQKQFLADVVQALDIGPAGPLVGVVQYGDIPATQFNLKTHVNSQDLKAAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRGGAPNVAVVMVDGWPTDKVEEVSRVARESGINVFFITVEGAAESEKQYVVEPNFSSKAVCRTNGFYSFNVQSWLSLHKTVQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTSNFRTVLQFVANLSKEFEISDTDTRIGAVQYTYEQRLEFGFDKYNSKNDILSAIRRVGYWSGGTSTGAAIQYALEQLFKKSKPNKRKVMILITDGRSYDDVRIPAMAAYRKGVITYAIGIAWAAQDELEVIATHPARDHSFFVDEFDNLYKFVPRIIQNICTEFNSQPRN", "length": 654, "header": "tr|A0A9J7K0L9-1|A0A9J7H736_CRIGR Computationally mapped isoform of Vitrin OS=Cricetulus griseus OX=10029 GN=Vit PE=4 SV=1 CANONICAL=A0A9J7H736-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K875-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H736/entry#A0A9J7K875-1", "sequence": { "sequence": "MRSGHLSVSASKLVLEIVLLVTGIHSNKEVAKKIKRPKFAVPQINCDVKAGKIINSEFMVKCPAGCQDPKYHVYGTGVYASYSSVCGAAVHSGVLDNSGGKILVQKVAGQSGYKGSYANGIQSLSLPRWRESFIISESKPQKGVTYPSTLTYSSAKNPAAQAGEATKAYEKPSITGTTTQPVTLTQALAIPVAEATHRTTSKPLAASVTSSPRPQPVGHRSQEMGLWSPTSYAGSQHSPGSHPGEMGVWKPGPVLLDSGFVPKEELSTQSSEPVSQGDPNCKVDLSFLIDGSTNIGKRRFRIQKQFLADVVQALDIGPAGPLVGVVQYGDIPATQFNLKTHVNSQDLKAAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRGGAPNVAVVMVDGWPTDKVEEVSRVARESGINVFFITVEGAAESEKQYVVEPNFSSKAVCRTNGFYSFNVQSWLSLHKTVQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTSNFRTVLQFVANLSKEFEISDTDTRIGAVQYTYEQRLEFGFDKYNSKNDILSAIRRVGYWSGGTSTGAAIQYALEQLFKKSKPNKRKVMILITDGRSYDDVRIPAMAAYRKGVITYAIGIAWAAQDELEVIATHPARDHSFFVDEFDNLYKFVPRIIQNICTEFNSQPRN", "length": 669, "header": "tr|A0A9J7K875-1|A0A9J7H736_CRIGR Computationally mapped isoform of Vitrin OS=Cricetulus griseus OX=10029 GN=Vit PE=4 SV=1 CANONICAL=A0A9J7H736-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K0L9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0L9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K0L9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0L9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766029", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766029", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H736", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H736" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H736", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H736" } ], "pmid": "" }, { "name": "positive regulation of cell-substrate adhesion", "id": "GO:0010811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010811", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H736", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H736" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "interstitial matrix", "id": "GO:0005614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005614", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H736", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H736" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H736" }, { "id": "PS50820", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50820" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LCCL", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 133, "start_aa": "Ala", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H736" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 308, "end_pos": 493, "start_aa": "Asp", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 459, "end_pos": 461 }, { "start_pos": 535, "end_pos": 537 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H530-1", "uniprot_ac": "A0A9J7H530", "uniprot_id": "A0A9J7H530_CRIGR", "mass": { "chemical_mass": 74762.0, "monoisotopic_mass": 74762.0 }, "refseq": { "ac": "XP_035303241", "name": "ankyrin repeat domain-containing protein 13B isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303241" }, "gene_names": [ { "name": "Ankrd13b", "type": "recommended", "evidence": [ { "id": "A0A9J7H530", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530" } ] }, { "name": "Ankrd13b", "type": "synonym", "evidence": [ { "id": "XP_035303241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303241" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain-containing protein 13B isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7H530", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein 13B isoform X3", "type": "synonym", "evidence": [ { "id": "XP_035303241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303241" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303241" } ] }, { "annotation": "Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H530", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530#function" }, { "database": "UniProtKB", "id": "ARBA00024956", "url": "https://www.uniprot.org/uniprotkb/ARBA00024956#function" }, { "database": "UniProtKB", "id": "A0A8C2LJV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJV3#function" }, { "database": "UniProtKB", "id": "A0A9J7GF13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF13#function" }, { "database": "UniProtKB", "id": "A0A9J7H244", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H244#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H530", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ankrd13b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530", "locus": {} } ], "crossref": [ { "id": "A0A9J7H530", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H530", "database": "AlphaFoldDB", "categories": [] }, { "id": "100757903", "url": "https://www.ncbi.nlm.nih.gov/gene/100757903", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055285", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055285", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757903", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757903", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H530", "url": "https://www.orthodb.org/?gene=A0A9J7H530", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12447", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12447", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12447:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12447:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11904", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11904", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303241", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LJV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LJV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GF13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GF13-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H244", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H244", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H244-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H244-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4E7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H530", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H530-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIPANASARKGPEGKYPLHYLVWHNRHRELEKEVRAGQVDIEQLDPRGRTPLHLATTLGHLECARVLLAHGADVGRENRSGWTVLQEAVSTRDLELVQLVLRYRDYQRVVKRLAGIPMLLEKLRKAQDFYVEMKWEFTSWVPLVSKICPSDTYKVWKSGQNLRVDTTLLGFDHMTWQRGNRSFVFRGQDTSAVVMEIDHDRRVVYMETLALAGQDRELLLAAAQPTEEQVLNRLTAPVVTTQLDTKNISFERNKTGILGWRSEKTEMVNGYEAKVYGASNVELITRTRTEHLSEQHKGKVKGCKTPLQSFLGIAEQHGGPQNGTLITQTLSQANPTAITAEEYFNPNFELGNRDMGRPMELTTKTQKFKAKLWLCEEHPLSLCEQVAPIIDLMAVSNALFAKLRDFITLRLPPGFPVKIEIPIFHILNARITFGNLNGCDEPVPSVRGSPSCETPSPGSDSSSVSSSSSTTSCRGCEISPALFEAPRGYSVLGGQREAATRDEDDDLLQFAIQQSLLEAGSEYDQVTIWEALTNSKPGTHPMSYEGRRQDRCPRCAGSGERSTNPPHPQERPTHAAAPAGAPGSSAQPSAQPGSRLQQPRVPELRRAAAAGNGAVCAGAGGEAAASTPRGGRAGAYPAALADRTVAPSARTLTHSAQDPGLRTCRAAAGVWSHRIGGAAAHQA", "length": 683, "header": "tr|A0A9J7H530-1|A0A9J7H530_CRIGR Isoform 1 of Ankyrin repeat domain-containing protein 13B isoform X3 OS=Cricetulus griseus OX=10029 GN=Ankrd13b PE=4 SV=1 CANONICAL=A0A9J7H530-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LJV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530/entry#A0A8C2LJV3-1", "sequence": { "sequence": "MIPANASARKGPEGKYPLHYLVWHNRHRELEKEVRAGQVDIEQLDPRGRTPLHLATTLGHLECARVLLAHGADVGRENRSGWTVLQEAVSTRDLELVQLVLRYRDYQRVVKRLAGIPMLLEKLRKAQDFYVEMKWEFTSWVPLVSKICPSDTYKVWKSGQNLRVDTTLLGFDHMTWQRGNRSFVFRGQDTSAVVMEIDHDRRVVYMETLALAGQDRELLLAAAQPTEEQVLNRLTAPVVTTQLDTKNISFERNKTGILGWRSEKTEMVNGYEAKVYGASNVELITRTRTEHLSEQHKGKVKGCKTPLQSFLGIAEQHGGPQNGTLITQTLSQANPTAITAEEYFNPNFELGNRDMGRPMELTTKTQKFKAKLWLCEEHPLSLCEQVAPIIDLMAVSNALFAKLRDFITLRLPPGFPVKIEIPIFHILNARITFGNLNGCDEPVPSVRGSPSCETPSPGSDSSSVSSSSSTTSCRGCEISPALFEAPRGYSVLGGQREAATRDEDDDLLQFAIQQSLLEAGSEYDQVTIWEALTNSKPGTHPMSYEGRRQDRSAPPTPQRQPVPPAAVPSPRPSPGPGSSSHVFRSYDEQLRLAMELSAQEQEERRRRARQEEEELERILRLSLTEQ", "length": 626, "header": "tr|A0A8C2LJV3-1|A0A8C2LJV3_CRIGR Computationally mapped isoform of Ankyrin repeat domain-containing protein 13B isoform X4 OS=Cricetulus griseus OX=10029 GN=Ankrd13b PE=4 SV=1 CANONICAL=A0A9J7H530-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GF13-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530/entry#A0A9J7GF13-1", "sequence": { "sequence": "MIPANASARKGPEGKYPLHYLVWHNRHRELEKEVRAGQVDIEQLDPRGRTPLHLATTLGHLECARVLLAHGADVGRENRSGWTVLQEAVSTRDLELVQLVLRYRDYQRVVKRLAGIPMLLEKLRKAQDFYVEMKWEFTSWVPLVSKICPSDTYKVWKSGQNLRVDTTLLGFDHMTWQRGNRSFVFRGQDTSAVVMEIDHDRRVVYMETLALAGQDRELLLAAAQPTEEQVLNRLTAPVVTTQLDTKNISFERNKTGILGWRSEKTEMVNGYEAKVYGASNVELITRTRTEHLSEQHKGKVKGCKTPLQSFLGIAEQHGGPQNGTLITQTLSQANPTAITAEEYFNPNFELGNRDMGRPMELTTKTQKFKAKLWLCEEHPLSLCEQVAPIIDLMAVSNALFAKLRDFITLRLPPGFPVKIEIPIFHILNARITFGNLNGCDEPVPSVRGSPSCETPSPGSDSSSVSSSSSTTSCRGCEISPALFEAPRGYSVLGGQREAATRDEDDDLLQFAIQQSLLEAGSEYDQVTIWEALTNSKPGTHPMSYEGRRQDRVGGQCSRHVQRAGT", "length": 565, "header": "tr|A0A9J7GF13-1|A0A9J7GF13_CRIGR Computationally mapped isoform of Ankyrin repeat domain-containing protein 13B isoform X5 OS=Cricetulus griseus OX=10029 GN=Ankrd13b PE=4 SV=1 CANONICAL=A0A9J7H530-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H244-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530/entry#A0A9J7H244-1", "sequence": { "sequence": "MIPANASARKGPEGKYPLHYLVWHNRHRELEKEVRAGQVDIEQLDPRGRTPLHLATTLGHLECARVLLAHGADVGRENRSGWTVLQEAVSTRDLELVQLVLRYRDYQRVVKRLAGIPMLLEKLRKAQDFYVEMKWEFTSWVPLVSKICPSDTYKVWKSGQNLRVDTTLLGFDHMTWQRGNRSFVFRGQDTSAVVMEIDHDRRVVYMETLALAGQDRELLLAAAQPTEEQVLNRLTAPVVTTQLDTKNISFERNKTGILGWRSEKTEMVNGYEAKVYGASNVELITRTRTEHLSEQHKGKVKGCKTPLQSFLGIAEQHGGPQNGTLITQTLSQANPTAITAEEYFNPNFELGNRDMGRPMELTTKTQKFKAKLWLCEEHPLSLCEQVAPIIDLMAVSNALFAKLRDFITLRLPPGFPVKIEIPIFHILNARITFGNLNGCDEPVPSVRGSPSCETPSPGSDSSSVSSSSSTTSCRGCEISPALFEAPRGYSVLGGQREAATRDEDDDLLQFAIQQSLLEAGSEYDQVTIWEALTNSKPGTHPMSYEGRRQDRSVPRRPKRT", "length": 560, "header": "tr|A0A9J7H244-1|A0A9J7H244_CRIGR Computationally mapped isoform of Ankyrin repeat domain-containing protein 13B isoform X6 OS=Cricetulus griseus OX=10029 GN=Ankrd13b PE=4 SV=1 CANONICAL=A0A9J7H530-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H4E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530/entry#A0A9J7H4E7-1", "sequence": { "sequence": "MLLEKLRKAQDFYVEMKWEFTSWVPLVSKICPSDTYKVWKSGQNLRVDTTLLGFDHMTWQRGNRSFVFRGQDTSAVVMEIDHDRRVVYMETLALAGQDRELLLAAAQPTEEQVLNRLTAPVVTTQLDTKNISFERNKTGILGWRSEKTEMVNGYEAKVYGASNVELITRTRTEHLSEQHKGKVKGCKTPLQSFLGIAEQHGGPQNGTLITQTLSQANPTAITAEEYFNPNFELGNRDMGRPMELTTKTQKFKAKLWLCEEHPLSLCEQVAPIIDLMAVSNALFAKLRDFITLRLPPGFPVKIEIPIFHILNARITFGNLNGCDEPVPSVRGSPSCETPSPGSDSSSVSSSSSTTSCRGCEISPALFEAPRGYSVLGGQREAATRDEDDDLLQFAIQQSLLEAGSEYDQVTIWEALTNSKPGTHPMSYEGRRQDRCPRCAGSGERSTNPPHPQERPTHAAAPAGAPGSSAQPSAQPGSRLQQPRVPELRRAAAAGNGAVCAGAGGEAAASTPRGGRAGAYPAALADRTVAPSARTLTHSAQDPGLRTCRAAAGVWSHRIGGAAAHQA", "length": 566, "header": "tr|A0A9J7H4E7-1|A0A9J7H4E7_CRIGR Computationally mapped isoform of Ankyrin repeat domain-containing protein 13B isoform X1 OS=Cricetulus griseus OX=10029 GN=Ankrd13b PE=4 SV=1 CANONICAL=A0A9J7H530-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H530-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530/entry#A0A9J7H530-1", "sequence": { "sequence": "MIPANASARKGPEGKYPLHYLVWHNRHRELEKEVRAGQVDIEQLDPRGRTPLHLATTLGHLECARVLLAHGADVGRENRSGWTVLQEAVSTRDLELVQLVLRYRDYQRVVKRLAGIPMLLEKLRKAQDFYVEMKWEFTSWVPLVSKICPSDTYKVWKSGQNLRVDTTLLGFDHMTWQRGNRSFVFRGQDTSAVVMEIDHDRRVVYMETLALAGQDRELLLAAAQPTEEQVLNRLTAPVVTTQLDTKNISFERNKTGILGWRSEKTEMVNGYEAKVYGASNVELITRTRTEHLSEQHKGKVKGCKTPLQSFLGIAEQHGGPQNGTLITQTLSQANPTAITAEEYFNPNFELGNRDMGRPMELTTKTQKFKAKLWLCEEHPLSLCEQVAPIIDLMAVSNALFAKLRDFITLRLPPGFPVKIEIPIFHILNARITFGNLNGCDEPVPSVRGSPSCETPSPGSDSSSVSSSSSTTSCRGCEISPALFEAPRGYSVLGGQREAATRDEDDDLLQFAIQQSLLEAGSEYDQVTIWEALTNSKPGTHPMSYEGRRQDRCPRCAGSGERSTNPPHPQERPTHAAAPAGAPGSSAQPSAQPGSRLQQPRVPELRRAAAAGNGAVCAGAGGEAAASTPRGGRAGAYPAALADRTVAPSARTLTHSAQDPGLRTCRAAAGVWSHRIGGAAAHQA", "length": 683, "header": "tr|A0A9J7H530-1|A0A9J7H530_CRIGR Isoform 1 of Ankyrin repeat domain-containing protein 13B isoform X3 OS=Cricetulus griseus OX=10029 GN=Ankrd13b PE=4 SV=1 CANONICAL=A0A9J7H530-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H530", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H530", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757903", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757903", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H530", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H530", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H530", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H530", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-modified protein reader activity", "id": "GO:0140036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140036", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H530", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of receptor internalization", "id": "GO:0002091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002091", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H530", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H530", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H530" }, { "id": "PF11904", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11904" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ankyrin repeat", "eco_id": "ECO_0000259", "start_pos": 163, "end_pos": 490, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 180, "end_pos": 182 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 322, "end_pos": 324 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H619-1", "uniprot_ac": "A0A9J7H619", "uniprot_id": "A0A9J7H619_CRIGR", "mass": { "chemical_mass": 174579.0, "monoisotopic_mass": 174579.0 }, "refseq": { "ac": "XP_035304550", "name": "ATP-binding cassette sub-family C member 9 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304550" }, "gene_names": [ { "name": "Abcc9", "type": "recommended", "evidence": [ { "id": "A0A9J7H619", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619" } ] }, { "name": "Abcc9", "type": "synonym", "evidence": [ { "id": "XP_035304550", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304550" } ] } ], "protein_names": [ { "name": "ATP-binding cassette sub-family C member 9 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035304550", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304550" }, { "id": "A0A9J7H619", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304550", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304550" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H619", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Abcc9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619", "locus": {} } ], "crossref": [ { "id": "cd03288", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03288", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03290", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03290", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18591", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18591", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18602", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18602", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769198", "url": "https://www.ncbi.nlm.nih.gov/gene/100769198", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769198", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769198", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H619", "url": "https://www.orthodb.org/?gene=A0A9J7H619", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223:SF173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223:SF173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304550", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304550", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H4H6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4H6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H619", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H619-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K156", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K156", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K156-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K156-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K8U7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8U7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K8U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8U7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCA4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLSFCGNNISSYNIYSGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYPQFGWNTSDLRFCITGVMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHRKPIDLKTIGKLPIAMRAVTNYVCLKDAYEEQKKKAADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETKNGTNNITGTSETLSSKEFLENAYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGLSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIVSVQKLNEFLLSDEIGEDSWRTGEGTLPFESCKKHTGVQSKPINRKQPGRYHLDSYEQSRRLRPAETEDIAIKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVYWSNVNESEPSFEATRSRSRYSVAYAAQKPWLLNATVEENITFGSPFNRQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEDDNMSTVMRLRTKMPWKTCWWYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYSINHTGKSDQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHYNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALVPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILTADLVIVMKRGNILEYDTPESLLAQEDGVFASFVRADM", "length": 1548, "header": "tr|A0A9J7H619-1|A0A9J7H619_CRIGR Isoform 1 of ATP-binding cassette sub-family C member 9 isoform X2 OS=Cricetulus griseus OX=10029 GN=Abcc9 PE=3 SV=1 CANONICAL=A0A9J7H619-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H4H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619/entry#A0A9J7H4H6-1", "sequence": { "sequence": "MYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETKNGTNNITGTSETLSSKEFLENAYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGLSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIVSVQKLNEFLLSDEIGEDSWRTGEGTLPFESCKKHTGVQSKPINRKQPGRYHLDSYEQSRRLRPAETEDIAIKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVYWSNVNESEPSFEATRRSRYSVAYAAQKPWLLNATVEENITFGSPFNRQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEDDNMSTVMRLRTKMPWKTCWWYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYSINHTGKSDQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHYNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALVPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILTADLVIVMKRGNILEYDTPESLLAQEDGVFASFVRADM", "length": 1259, "header": "tr|A0A9J7H4H6-1|A0A9J7H619_CRIGR Computationally mapped isoform of ATP-binding cassette sub-family C member 9 isoform X2 OS=Cricetulus griseus OX=10029 GN=Abcc9 PE=3 SV=1 CANONICAL=A0A9J7H619-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H619-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619/entry#A0A9J7H619-1", "sequence": { "sequence": "MSLSFCGNNISSYNIYSGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYPQFGWNTSDLRFCITGVMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHRKPIDLKTIGKLPIAMRAVTNYVCLKDAYEEQKKKAADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETKNGTNNITGTSETLSSKEFLENAYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGLSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIVSVQKLNEFLLSDEIGEDSWRTGEGTLPFESCKKHTGVQSKPINRKQPGRYHLDSYEQSRRLRPAETEDIAIKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVYWSNVNESEPSFEATRSRSRYSVAYAAQKPWLLNATVEENITFGSPFNRQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEDDNMSTVMRLRTKMPWKTCWWYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYSINHTGKSDQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHYNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALVPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILTADLVIVMKRGNILEYDTPESLLAQEDGVFASFVRADM", "length": 1548, "header": "tr|A0A9J7H619-1|A0A9J7H619_CRIGR Isoform 1 of ATP-binding cassette sub-family C member 9 isoform X2 OS=Cricetulus griseus OX=10029 GN=Abcc9 PE=3 SV=1 CANONICAL=A0A9J7H619-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K156-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619/entry#A0A9J7K156-1", "sequence": { "sequence": "MSLSFCGNNISSYNIYSGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYPQFGWNTSDLRFCITGVMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHRKPIDLKTIGKLPIAMRAVTNYVCLKDAYEEQKKKAADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETKNGTNNITGTSETLSSKEFLENAYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGLSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIVSVQKLNEFLLSDEIGEDSWRTGEGTLPFESCKKHTGVQSKPINRKQPGRYHLDSYEQSRRLRPAETEDIAIKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVYWSNRSRYSVAYAAQKPWLLNATVEENITFGSPFNRQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEDDNMSTVMRLRTKMPWKTCWWYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYSINHTGKSDQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHYNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALVPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIVDAGLVLVFSEGILVECDTGPNLLEHKNGLFSTLVMTNK", "length": 1535, "header": "tr|A0A9J7K156-1|A0A9J7H619_CRIGR Computationally mapped isoform of ATP-binding cassette sub-family C member 9 isoform X2 OS=Cricetulus griseus OX=10029 GN=Abcc9 PE=3 SV=1 CANONICAL=A0A9J7H619-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K8U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619/entry#A0A9J7K8U7-1", "sequence": { "sequence": "MSLSFCGNNISSYNIYSGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYPQFGWNTSDLRFCITGVMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHRKPIDLKTIGKLPIAMRAVTNYVCLKDAYEEQKKKAADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETKNGTNNITGTSETLSSKEFLENAYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGLSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIVSVQKLNEFLLSDEIGEDSWRTGEGTLPFESCKKHTGVQSKPINRKQPGRYHLDSYEQSRRLRPAETEDIAIKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVYWSNVNESEPSFEATRSRSRYSVAYAAQKPWLLNATVEENITFGSPFNRQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEDDNMSTVMRLRTKMPWKTCWWYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYSINHTGKSDQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHYNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALVPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIVDAGLVLVFSEGILVECDTGPNLLEHKNGLFSTLVMTNK", "length": 1548, "header": "tr|A0A9J7K8U7-1|A0A9J7H619_CRIGR Computationally mapped isoform of ATP-binding cassette sub-family C member 9 isoform X2 OS=Cricetulus griseus OX=10029 GN=Abcc9 PE=3 SV=1 CANONICAL=A0A9J7H619-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619/entry#A0A9J7KAU1-1", "sequence": { "sequence": "MSLSFCGNNISSYNIYSGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYPQFGWNTSDLRFCITGVMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHRKPIDLKTIGKLPIAMRAVTNYVCLKDAYEEQKKKAADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETKNGTNNITGTSETLSSKEFLENAYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGLSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIVSVQKLNEFLLSDEIGEDSWRTGEGTLPFESCKKHTGVVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVYWSNVNESEPSFEATRSRSRYSVAYAAQKPWLLNATVEENITFGSPFNRQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEDDNMSTVMRLRTKMPWKTCWWYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYSINHTGKSDQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHYNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALVPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIVDAGLVLVFSEGILVECDTGPNLLEHKNGLFSTLVMTNK", "length": 1513, "header": "tr|A0A9J7KAU1-1|A0A9J7H619_CRIGR Computationally mapped isoform of ATP-binding cassette sub-family C member 9 isoform X2 OS=Cricetulus griseus OX=10029 GN=Abcc9 PE=3 SV=1 CANONICAL=A0A9J7H619-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KCA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619/entry#A0A9J7KCA4-1", "sequence": { "sequence": "MSLSFCGNNISSYNIYSGVLQNPCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYPQFGWNTSDLRFCITGVMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHRKPIDLKTIGKLPIAMRAVTNYVCLKDAYEEQKKKAADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETKNGTNNITGTSETLSSKEFLENAYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGLSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIVSVQKLNEFLLSDEIGEDSWRTGEGTLPFESCKKHTGVQSKPINRKQPGRYHLDSYEQSRRLRPAETEDIAIKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVYWSNRSRYSVAYAAQKPWLLNATVEENITFGSPFNRQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEDDNMSTVMRLRTKMPWKTCWWYLTSGGFFLLFLMIFSKLLKHSVIVAIDYWLATWTSEYSINHTGKSDQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHYNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALVPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILTADLVIVMKRGNILEYDTPESLLAQEDGVFASFVRADM", "length": 1535, "header": "tr|A0A9J7KCA4-1|A0A9J7H619_CRIGR Computationally mapped isoform of ATP-binding cassette sub-family C member 9 isoform X2 OS=Cricetulus griseus OX=10029 GN=Abcc9 PE=3 SV=1 CANONICAL=A0A9J7H619-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K156", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K156" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K156", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K156" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769198", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769198", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H619", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H619", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619" } ], "pmid": "" }, { "name": "sulfonylurea receptor activity", "id": "GO:0008281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008281", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H619", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H619", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H619", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H619", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H619", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619" } ], "pmid": "" }, { "name": "response to ATP", "id": "GO:0033198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033198", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H619", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H619", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H619" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1024, "end_pos": 1026, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1447, "end_pos": 1449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 762, "end_pos": 764, "annotation": "n_glycosylation_sequon" }, { "start_pos": 768, "end_pos": 770, "annotation": "n_glycosylation_sequon" }, { "start_pos": 810, "end_pos": 812, "annotation": "n_glycosylation_sequon" }, { "start_pos": 965, "end_pos": 967, "annotation": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304932", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304932" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H503", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H503" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100752185", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H503", "locus": {} } ], "crossref": [ { "id": "100752185", "url": "https://www.ncbi.nlm.nih.gov/gene/100752185", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752185", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752185", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H503", "url": "https://www.orthodb.org/?gene=A0A9J7H503", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304932", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304932", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H503", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H503", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H503-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H503-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLFFKLPHCEFDSSHINEDLIMEQGREACYSCEESFMTDYKMTMTVGSGHFSEVKMDFHVLTVTCVAVKVLRMKNALLVANXVSILKSLQHPNIIKLFHVVQSRDTTYLVMEHTSQGDLLRHILELGSLKESEAQRLFTQILFAMQYCHNNHIAHRDIKANNILLDYRVNAKLCDFALLAKMTRGQKLSDFCGTLLYCALELLVEKAYDGCASDIWSLGVLLFLMVVGRFPFWASSSEGVRRQIVAANFTIPQHVSIDIFNVIVEMLMFNQDRRPTIGQIMRRPLIGFHHLFPHRNALAL", "length": 301, "header": "tr|A0A9J7H503-1|A0A9J7H503_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=LOC100752185 PE=4 SV=1 CANONICAL=A0A9J7H503-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H503-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H503/entry#A0A9J7H503-1", "sequence": { "sequence": "MTLFFKLPHCEFDSSHINEDLIMEQGREACYSCEESFMTDYKMTMTVGSGHFSEVKMDFHVLTVTCVAVKVLRMKNALLVANXVSILKSLQHPNIIKLFHVVQSRDTTYLVMEHTSQGDLLRHILELGSLKESEAQRLFTQILFAMQYCHNNHIAHRDIKANNILLDYRVNAKLCDFALLAKMTRGQKLSDFCGTLLYCALELLVEKAYDGCASDIWSLGVLLFLMVVGRFPFWASSSEGVRRQIVAANFTIPQHVSIDIFNVIVEMLMFNQDRRPTIGQIMRRPLIGFHHLFPHRNALAL", "length": 301, "header": "tr|A0A9J7H503-1|A0A9J7H503_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=LOC100752185 PE=4 SV=1 CANONICAL=A0A9J7H503-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": 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"url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": 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{ "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] } ] }, { "uniprot_ac": "A0A8C2N185", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] } ] }, { "uniprot_ac": "A0A8C2N210", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] } ] }, { "uniprot_ac": "A0A8C2N457", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] } ] }, { "uniprot_ac": "A0A8C2N4W2", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": 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H(+).", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": 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} ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F821", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] } ] }, { "uniprot_ac": "A0A9J7F8T0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] } ] }, { "uniprot_ac": "A0A9J7G5N9", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": 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"https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] } ] }, { "uniprot_ac": "A0A9J7G9D1", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] } ] }, { "uniprot_ac": "A0A9J7GAB0", "gene_name": "Pkn3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] } ] }, { "uniprot_ac": "A0A9J7GAF4", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] } ] }, { "uniprot_ac": "A0A9J7GD76", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] } ] }, { "uniprot_ac": "A0A9J7GES8", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] } ] }, { "uniprot_ac": "A0A9J7GF59", "gene_name": "LOC103160391", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A9J7GLT3", "gene_name": "LOC113838166", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] } ] }, { "uniprot_ac": "A0A9J7GMF3", "gene_name": "LOC103158537", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] } ] }, { "uniprot_ac": "A0A9J7GMK5", "gene_name": "Sbk3", 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] } ] }, { "uniprot_ac": "A0A9J7H3M5", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] } ] }, { "uniprot_ac": "A0A9J7H3N1", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H4T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4T9" } ] } ] }, { "uniprot_ac": "A0A9J7H503", "gene_name": "LOC100752185", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H503", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H503" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H503", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H503" } ] } ] }, { "uniprot_ac": "A0A9J7H540", "gene_name": "LOC113837157", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ] } ] }, { "uniprot_ac": "A0A9J7J1N3", "gene_name": "Limk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J1N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J1N3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7J1N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J1N3" } ] } ] }, { "uniprot_ac": "A0A9J7J5Z8", "gene_name": "Camk2g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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{ "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP 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"ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JQZ1", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] } ] }, { "uniprot_ac": "A0A9J7JRI3", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] } ] }, { "uniprot_ac": "G3IN30", "gene_name": "Plk1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] } ] }, { "uniprot_ac": "O55076", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] } ] }, { "uniprot_ac": "P25321", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P25321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25321" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P25321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25321" } ] } ] }, { "uniprot_ac": "P50310", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "P50310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50310" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P50310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50310" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "P50310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P50310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50310" } ] } ] }, { "uniprot_ac": "P68180", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68180" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P68180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68180" } ] } ] }, { "uniprot_ac": "Q63980", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q63980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q63980" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q63980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q63980" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H503", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H503" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 293, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 249, "end_pos": 251 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H8C4-1", "uniprot_ac": "A0A9J7H8C4", "uniprot_id": "A0A9J7H8C4_CRIGR", "mass": { "chemical_mass": 153409.0, "monoisotopic_mass": 153409.0 }, "refseq": { "ac": "XP_035305132", "name": "zinc finger protein 420 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305132" }, "gene_names": [ { "name": "LOC103161319", "type": "recommended", "evidence": [ { "id": "A0A9J7H8C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4" } ] }, { "name": "LOC103161319", "type": "synonym", "evidence": [ { "id": "XP_035305132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305132" } ] } ], "protein_names": [ { "name": "Zinc finger protein 420 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H8C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 420 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305132" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305132" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8C4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8C4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC103161319", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4", "locus": {} } ], "crossref": [ { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "103161319", "url": "https://www.ncbi.nlm.nih.gov/gene/103161319", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103161319", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103161319", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H8C4", "url": "https://www.orthodb.org/?gene=A0A9J7H8C4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379:SF122", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379:SF122", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305132", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H512", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H512", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H512-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H512-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5D0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5D0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6B5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6B5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H743", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H743", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H743-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H743-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7H4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7H4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8C4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8G2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9H1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9D4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9D4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBB8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKRGMAADQAKHKKSMVFSDVSLDFSQEEWECLGPAQRDLYRDVMLENYSNLLSVAGLPIPKPQVISLLEQGKEPWMIGKELTRGLCSALESMCESKLLSLKKEVYEIESCQRELMGLKKHGLEYPSFRDVLECGSQFTSQLGYQNGHLSQEILSREYMPTFVQQTFLTLRQIVNNDEKPYECKKCRKVFTQNSQFIQHQRVHLGEKSYECKQCGKFFSCGSHVTRHLKIHTGEKPFECKDCGKAFSCSSYLSQHQRIHTGKKPYECKECGKAFSYCSNLIDHQRIHTGEKPYACKVCGKAFTKSSQLFQHVRVHTGEKPYECKECGKAFTQSSKLVQHQRTHTGEKPYECKECGKAFSSGSALTNHQRIHTGEKPYECKECGKAFTQSSQLRQHQRIHAGEKPFECLECGKAFTQNSQLFQHQRVHSDEKPYECNKCGKAFNKCSNLTRHLRIHSDDKSHSCKECGETFSNDSDLIRHQEIHGNEEKKLLKCNDCEKVFRQSSSLTLHQRIHTGEKPYECIECGKAFSQRSNLVQHHRVHTGEKPYECKECRKAFSQNAHLAQHLRIHTGEKPYECEVCRKAFSQFAYLAQHQRIHTGEKPYECVECGKAFSNRSSIAQHQRVHTGEKPYECRVCGKAFSLRAYLTVHQRIHTGERPYACKECGKAFSQNSHLAQHQRIHTGEKPYKCQECKKAFSQIAYLAQHQRVHTGEKPYECIKCGKAFSNDSSLTQHWRVHTGEKPYKCNVCEKAFSYCGSLAQHQRIHTGERPYECKECKRTFRQYAHLAHHQRTHSGDSLEKKLLKCNDCEKVFRQSSSLTLHQRIHTGEKPYECIECGKAFSQRSNLVQHHRVHTGEKPYECKECRKAFSQNAHLAQHLRIHTGEKPYECEVCRKAFSQFAYLAQHQRIHTGEKPYECVECGKAFSNRSSIAQHQRVHTGEKPYECRVCGKAFSLRAYLTVHQRIHTGERPYACKECGKAFSQNSHLAQHQRIHTGEKPYKCQECKKAFSQIAYLAQHQRVHTGEKPYECIKCGKAFSNDSSLTQHWRVHTGEKPYKCNVCEKAFSYCGSLAQHQRIHTGERPYECKECGKSFTNGSDLQVHQRIHTGGKPYKCSDCGKCYKQKSPLQHQRIHTGEKPYACGQCGRAFRQKTALTRHHKTHTGEKAYGCGQCGSAFRKKSYLVDHQRTHTGEKPYACAECGKAFVQKTTLTVHRRTHTGEKPYLCADCGKAFCQKTTLTLHRRIHTGEKPYACADCGRAFRQKAILTVHRRTHTGEKANGCPQCGKAFSRKSNLLRHQKTHTGEKPYGCQHCGKAFSCKSNLAAHHKTHRAADGGRVP", "length": 1338, "header": "tr|A0A9J7H8C4-1|A0A9J7H8C4_CRIGR Isoform 1 of Zinc finger protein 420 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC103161319 PE=3 SV=1 CANONICAL=A0A9J7H8C4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H512-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4/entry#A0A9J7H512-1", "sequence": { "sequence": "MIRKLEQGKELWTERIFPSQSYLEDEDVPVKFKDCLDKHPESTVLINHKKLIQERSSLYRRTPGKSHAISKTLCDYTSRGKASKTISEFIIGGDLNPARDRFGDGGWGTRTLDSPRGEAQAPSAPPGKQRPRGPSPERLPRHQAAQAPIQVPGQPFLLAGDACDGPGLLPGAAAFPGGLGYHGDGGGLGYHGDGGLGYHGDGLASGVGPLGPPERRPSAAACSKYGKLLGRKPPLFLTHPRPPPATATATTPAPVAAADGKEKPFQCPYCGNAFRRKSYLLEHQRIHTGEKPYACGQCGRAFRQKTALTLHERTHAEGRPYLCADCGKAFRQKATLSRHHKTHTGEKAYGCGQCGSAFRKKSYLVDHQRTHTGEKPYACAECGKAFVQKTTLTVHRRTHTGEKPYLCADCGKAFCQKTTLTLHRRIHTGEKPYACADCGRAFRQKAILTVHRRTHTGEKANGCPQCGKAFSRKSNLLRHQKTHTGEKPYGCQHCGKAFSCKSNLAAHHKTHRAADGGRVP", "length": 520, "header": "tr|A0A9J7H512-1|A0A9J7H512_CRIGR Computationally mapped isoform of Zinc finger protein 382 isoform X10 OS=Cricetulus griseus OX=10029 GN=LOC103161319 PE=3 SV=1 CANONICAL=A0A9J7H8C4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H5D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4/entry#A0A9J7H5D0-1", "sequence": { "sequence": "MGRPGRKPGGHAGPGLFPFPKDEPRQRDSSLTNLKGMSKGPVSFKDVTVDFTQEEWQHLDPDQKALYRDVMLENYCHFVSVGFPITKPDMIRKLEQGKELWTERIFPSQSYLDEDVPVKFKDCLDKHPESTVLINHKKLIQERSSLYRRTPGKSHAISKTLCDYTSRGKASKTISEFIIGGDLNPARDRFGDGGWGTRTLDSPRGEAQAPSAPPGKQRPRGPSPERLPRHQAAQAPIQVPGQPFLLAGDACDGPGLLPGAAAFPGGLGYHGDGGGLGYHGDGGLGYHGDGLASGVGPLGPPERRPSAAACSKYGKLLGRKPPLFLTHPRPPPATATATTPAPVAAADGKEKPFQCPYCGNAFRRKSYLLEHQRIHTGEKPYACGQCGRAFRQKTALTLHERTHAEGRPYLCADCGKAFRQKATLSRHHKTHTGEKAYGCGQCGSAFRKKSYLVDHQRTHTGEKPYACAECGKAFVQKTTLTVHRRTHTGEKPYLCADCGKAFCQKTTLTLHRRIHTGEKPYACADCGRAFRQKAILTVHRRTHTGEKANGCPQCGKAFSRKSNLLRHQKTHTGEKPYGCQHCGKAFSCKSNLAAHHKTHRAADGGRVP", "length": 608, "header": "tr|A0A9J7H5D0-1|A0A9J7H5D0_CRIGR Computationally mapped isoform of Zinc finger protein 382 isoform X4 OS=Cricetulus griseus OX=10029 GN=LOC103161319 PE=3 SV=1 CANONICAL=A0A9J7H8C4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H6B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4/entry#A0A9J7H6B5-1", "sequence": { "sequence": "MRMPGSFLSRKTSQDNGIRLSQISKACLSVPLQGPVSFKDVTVDFTQEEWQHLDPDQKALYRDVMLENYCHFVSVGFPITKPDMIRKLEQGKELWTERIFPSQSYLEDEDVPVKFKDCLDKHPESTVLINHKKLIQERSSLYRRTPGKSHAISKTLCDYTSRGKASKTISEFIIGGDLNPARDRFGDGGWGTRTLDSPRGEAQAPSAPPGKQRPRGPSPERLPRHQAAQAPIQVPGQPFLLAGDACDGPGLLPGAAAFPGGLGYHGDGGGLGYHGDGGLGYHGDGLASGVGPLGPPERRPSAAACSKYGKLLGRKPPLFLTHPRPPPATATATTPAPVAAADGKEKPFQCPYCGNAFRRKSYLLEHQRIHTGEKPYACGQCGRAFRQKTALTLHERTHAEGRPYLCADCGKAFRQKATLSRHHKTHTGEKAYGCGQCGSAFRKKSYLVDHQRTHTGEKPYACAECGKAFVQKTTLTVHRRTHTGEKPYLCADCGKAFCQKTTLTLHRRIHTGEKPYACADCGRAFRQKAILTVHRRTHTGEKANGCPQCGKAFSRKSNLLRHQKTHTGEKPYGCQHCGKAFSCKSNLAAHHKTHRAADGGRVP", "length": 603, "header": "tr|A0A9J7H6B5-1|A0A9J7H6B5_CRIGR Computationally mapped isoform of Zinc finger protein 382 isoform X6 OS=Cricetulus griseus OX=10029 GN=LOC103161319 PE=3 SV=1 CANONICAL=A0A9J7H8C4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H743-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4/entry#A0A9J7H743-1", "sequence": { "sequence": "MGSFLSRKTSQDNGIRLSQISKACLSVPLQGPVSFKDVTVDFTQEEWQHLDPDQKALYRDVMLENYCHFVSVGFPITKPDMIRKLEQGKELWTERIFPSQSYLEDEDVPVKFKDCLDKHPESTVLINHKKLIQERSSLYRRTPGKSHAISKTLCDYTSRGKASKTISEFIIGGDLNPARDRFGDGGWGTRTLDSPRGEAQAPSAPPGKQRPRGPSPERLPRHQAAQAPIQVPGQPFLLAGDACDGPGLLPGAAAFPGGLGYHGDGGGLGYHGDGGLGYHGDGLASGVGPLGPPERRPSAAACSKYGKLLGRKPPLFLTHPRPPPATATATTPAPVAAADGKEKPFQCPYCGNAFRRKSYLLEHQRIHTGEKPYACGQCGRAFRQKTALTLHERTHAEGRPYLCADCGKAFRQKATLSRHHKTHTGEKAYGCGQCGSAFRKKSYLVDHQRTHTGEKPYACAECGKAFVQKTTLTVHRRTHTGEKPYLCADCGKAFCQKTTLTLHRRIHTGEKPYACADCGRAFRQKAILTVHRRTHTGEKANGCPQCGKAFSRKSNLLRHQKTHTGEKPYGCQHCGKAFSCKSNLAAHHKTHRAADGGRVP", "length": 600, "header": "tr|A0A9J7H743-1|A0A9J7H743_CRIGR Computationally mapped isoform of Zinc finger protein 382 isoform X8 OS=Cricetulus griseus OX=10029 GN=LOC103161319 PE=3 SV=1 CANONICAL=A0A9J7H8C4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4/entry#A0A9J7H7H4-1", "sequence": { "sequence": "MGRPGRKPGGHAGPGLFPFPKDEPRQRDSSLTNLKGMSKGPVSFKDVTVDFTQEEWQHLDPDQKALYRDVMLENYCHFVSVGFPITKPDMIRKLEQGKELWTERIFPSQSYLEDEDVPVKFKDCLDKHPESTVLINHKKLIQERSSLYRRTPGKSHAISKTLCDYTSRGKASKTISEFIIGGDLNPARDRFGDGGWGTRTLDSPRGEAQAPSAPPGKQRPRGPSPERLPRHQAAQAPIQVPGQPFLLAGDACDGPGLLPGAAAFPGGLGYHGDGGGLGYHGDGGLGYHGDGLASGVGPLGPPERRPSAAACSKYGKLLGRKPPLFLTHPRPPPATATATTPAPVAAADGKEKPFQCPYCGNAFRRKSYLLEHQRIHTGEKPYACGQCGRAFRQKTALTLHERTHAEGRPYLCADCGKAFRQKATLSRHHKTHTGEKAYGCGQCGSAFRKKSYLVDHQRTHTGEKPYACAECGKAFVQKTTLTVHRRTHTGEKPYLCADCGKAFCQKTTLTLHRRIHTGEKPYACADCGRAFRQKAILTVHRRTHTGEKANGCPQCGKAFSRKSNLLRHQKTHTGEKPYGCQHCGKAFSCKSNLAAHHKTHRAADGGRVP", "length": 609, "header": "tr|A0A9J7H7H4-1|A0A9J7H7H4_CRIGR Computationally mapped isoform of Zinc finger protein 382 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC103161319 PE=3 SV=1 CANONICAL=A0A9J7H8C4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H8C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4/entry#A0A9J7H8C4-1", "sequence": { "sequence": "MEKRGMAADQAKHKKSMVFSDVSLDFSQEEWECLGPAQRDLYRDVMLENYSNLLSVAGLPIPKPQVISLLEQGKEPWMIGKELTRGLCSALESMCESKLLSLKKEVYEIESCQRELMGLKKHGLEYPSFRDVLECGSQFTSQLGYQNGHLSQEILSREYMPTFVQQTFLTLRQIVNNDEKPYECKKCRKVFTQNSQFIQHQRVHLGEKSYECKQCGKFFSCGSHVTRHLKIHTGEKPFECKDCGKAFSCSSYLSQHQRIHTGKKPYECKECGKAFSYCSNLIDHQRIHTGEKPYACKVCGKAFTKSSQLFQHVRVHTGEKPYECKECGKAFTQSSKLVQHQRTHTGEKPYECKECGKAFSSGSALTNHQRIHTGEKPYECKECGKAFTQSSQLRQHQRIHAGEKPFECLECGKAFTQNSQLFQHQRVHSDEKPYECNKCGKAFNKCSNLTRHLRIHSDDKSHSCKECGETFSNDSDLIRHQEIHGNEEKKLLKCNDCEKVFRQSSSLTLHQRIHTGEKPYECIECGKAFSQRSNLVQHHRVHTGEKPYECKECRKAFSQNAHLAQHLRIHTGEKPYECEVCRKAFSQFAYLAQHQRIHTGEKPYECVECGKAFSNRSSIAQHQRVHTGEKPYECRVCGKAFSLRAYLTVHQRIHTGERPYACKECGKAFSQNSHLAQHQRIHTGEKPYKCQECKKAFSQIAYLAQHQRVHTGEKPYECIKCGKAFSNDSSLTQHWRVHTGEKPYKCNVCEKAFSYCGSLAQHQRIHTGERPYECKECKRTFRQYAHLAHHQRTHSGDSLEKKLLKCNDCEKVFRQSSSLTLHQRIHTGEKPYECIECGKAFSQRSNLVQHHRVHTGEKPYECKECRKAFSQNAHLAQHLRIHTGEKPYECEVCRKAFSQFAYLAQHQRIHTGEKPYECVECGKAFSNRSSIAQHQRVHTGEKPYECRVCGKAFSLRAYLTVHQRIHTGERPYACKECGKAFSQNSHLAQHQRIHTGEKPYKCQECKKAFSQIAYLAQHQRVHTGEKPYECIKCGKAFSNDSSLTQHWRVHTGEKPYKCNVCEKAFSYCGSLAQHQRIHTGERPYECKECGKSFTNGSDLQVHQRIHTGGKPYKCSDCGKCYKQKSPLQHQRIHTGEKPYACGQCGRAFRQKTALTRHHKTHTGEKAYGCGQCGSAFRKKSYLVDHQRTHTGEKPYACAECGKAFVQKTTLTVHRRTHTGEKPYLCADCGKAFCQKTTLTLHRRIHTGEKPYACADCGRAFRQKAILTVHRRTHTGEKANGCPQCGKAFSRKSNLLRHQKTHTGEKPYGCQHCGKAFSCKSNLAAHHKTHRAADGGRVP", "length": 1338, "header": "tr|A0A9J7H8C4-1|A0A9J7H8C4_CRIGR Isoform 1 of Zinc finger protein 420 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC103161319 PE=3 SV=1 CANONICAL=A0A9J7H8C4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H8G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4/entry#A0A9J7H8G2-1", "sequence": { "sequence": "MIRKLEQGKELWTERIFPSQSYLDEDVPVKFKDCLDKHPESTVLINHKKLIQERSSLYRRTPGKSHAISKTLCDYTSRGKASKTISEFIIGGDLNPARDRFGDGGWGTRTLDSPRGEAQAPSAPPGKQRPRGPSPERLPRHQAAQAPIQVPGQPFLLAGDACDGPGLLPGAAAFPGGLGYHGDGGGLGYHGDGGLGYHGDGLASGVGPLGPPERRPSAAACSKYGKLLGRKPPLFLTHPRPPPATATATTPAPVAAADGKEKPFQCPYCGNAFRRKSYLLEHQRIHTGEKPYACGQCGRAFRQKTALTLHERTHAEGRPYLCADCGKAFRQKATLSRHHKTHTGEKAYGCGQCGSAFRKKSYLVDHQRTHTGEKPYACAECGKAFVQKTTLTVHRRTHTGEKPYLCADCGKAFCQKTTLTLHRRIHTGEKPYACADCGRAFRQKAILTVHRRTHTGEKANGCPQCGKAFSRKSNLLRHQKTHTGEKPYGCQHCGKAFSCKSNLAAHHKTHRAADGGRVP", "length": 519, "header": "tr|A0A9J7H8G2-1|A0A9J7H8G2_CRIGR Computationally mapped isoform of Zinc finger protein 382 isoform X11 OS=Cricetulus griseus OX=10029 GN=LOC103161319 PE=3 SV=1 CANONICAL=A0A9J7H8C4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4/entry#A0A9J7H9H1-1", "sequence": { "sequence": "MRMPVRMRGACWGLFPFPKDEPRQRDSSLTNLKGMSKGPVSFKDVTVDFTQEEWQHLDPDQKALYRDVMLENYCHFVSVGFPITKPDMIRKLEQGKELWTERIFPSQSYLEDEDVPVKFKDCLDKHPESTVLINHKKLIQERSSLYRRTPGKSHAISKTLCDYTSRGKASKTISEFIIGGDLNPARDRFGDGGWGTRTLDSPRGEAQAPSAPPGKQRPRGPSPERLPRHQAAQAPIQVPGQPFLLAGDACDGPGLLPGAAAFPGGLGYHGDGGGLGYHGDGGLGYHGDGLASGVGPLGPPERRPSAAACSKYGKLLGRKPPLFLTHPRPPPATATATTPAPVAAADGKEKPFQCPYCGNAFRRKSYLLEHQRIHTGEKPYACGQCGRAFRQKTALTLHERTHAEGRPYLCADCGKAFRQKATLSRHHKTHTGEKAYGCGQCGSAFRKKSYLVDHQRTHTGEKPYACAECGKAFVQKTTLTVHRRTHTGEKPYLCADCGKAFCQKTTLTLHRRIHTGEKPYACADCGRAFRQKAILTVHRRTHTGEKANGCPQCGKAFSRKSNLLRHQKTHTGEKPYGCQHCGKAFSCKSNLAAHHKTHRAADGGRVP", "length": 607, "header": "tr|A0A9J7H9H1-1|A0A9J7H9H1_CRIGR Computationally mapped isoform of Zinc finger protein 382 isoform X5 OS=Cricetulus griseus OX=10029 GN=LOC103161319 PE=3 SV=1 CANONICAL=A0A9J7H8C4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K9D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4/entry#A0A9J7K9D4-1", "sequence": { "sequence": "MRDEDAWLFPFPKDEPRQRDSSLTNLKGMSKGPVSFKDVTVDFTQEEWQHLDPDQKALYRDVMLENYCHFVSVGFPITKPDMIRKLEQGKELWTERIFPSQSYLEDEDVPVKFKDCLDKHPESTVLINHKKLIQERSSLYRRTPGKSHAISKTLCDYTSRGKASKTISEFIIGGDLNPARDRFGDGGWGTRTLDSPRGEAQAPSAPPGKQRPRGPSPERLPRHQAAQAPIQVPGQPFLLAGDACDGPGLLPGAAAFPGGLGYHGDGGGLGYHGDGGLGYHGDGLASGVGPLGPPERRPSAAACSKYGKLLGRKPPLFLTHPRPPPATATATTPAPVAAADGKEKPFQCPYCGNAFRRKSYLLEHQRIHTGEKPYACGQCGRAFRQKTALTLHERTHAEGRPYLCADCGKAFRQKATLSRHHKTHTGEKAYGCGQCGSAFRKKSYLVDHQRTHTGEKPYACAECGKAFVQKTTLTVHRRTHTGEKPYLCADCGKAFCQKTTLTLHRRIHTGEKPYACADCGRAFRQKAILTVHRRTHTGEKANGCPQCGKAFSRKSNLLRHQKTHTGEKPYGCQHCGKAFSCKSNLAAHHKTHRAADGGRVP", "length": 601, "header": "tr|A0A9J7K9D4-1|A0A9J7H8C4_CRIGR Computationally mapped isoform of Zinc finger protein 420 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC103161319 PE=3 SV=1 CANONICAL=A0A9J7H8C4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4/entry#A0A9J7KBB8-1", "sequence": { "sequence": "MSKGPVSFKDVTVDFTQEEWQHLDPDQKALYRDVMLENYCHFVSVGFPITKPDMIRKLEQGKELWTERIFPSQSYLEDEDVPVKFKDCLDKHPESTVLINHKKLIQERSSLYRRTPGKSHAISKTLCDYTSRGKASKTISEFIIGGDLNPARDRFGDGGWGTRTLDSPRGEAQAPSAPPGKQRPRGPSPERLPRHQAAQAPIQVPGQPFLLAGDACDGPGLLPGAAAFPGGLGYHGDGGGLGYHGDGGLGYHGDGLASGVGPLGPPERRPSAAACSKYGKLLGRKPPLFLTHPRPPPATATATTPAPVAAADGKEKPFQCPYCGNAFRRKSYLLEHQRIHTGEKPYACGQCGRAFRQKTALTLHERTHAEGRPYLCADCGKAFRQKATLSRHHKTHTGEKAYGCGQCGSAFRKKSYLVDHQRTHTGEKPYACAECGKAFVQKTTLTVHRRTHTGEKPYLCADCGKAFCQKTTLTLHRRIHTGEKPYACADCGRAFRQKAILTVHRRTHTGEKANGCPQCGKAFSRKSNLLRHQKTHTGEKPYGCQHCGKAFSCKSNLAAHHKTHRAADGGRVP", "length": 573, "header": "tr|A0A9J7KBB8-1|A0A9J7H8C4_CRIGR Computationally mapped isoform of Zinc finger protein 420 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC103161319 PE=3 SV=1 CANONICAL=A0A9J7H8C4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9D4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9D4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9D4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9D4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103161319", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103161319", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8C4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8C4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8C4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8C4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8C4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8C4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8C4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8C4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8C4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8C4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4" } ], "pmid": "" }, { "name": "PcG protein complex", "id": "GO:0031519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8C4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8C4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8C4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", 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"Other" ] }, { "id": "PF02736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302999", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H517", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H517", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H517-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H517-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVTLSVPGRKVAARAGPVPEAAQPFLFTPRTPNVGGPGGPQVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFVSKGTMRVAIWETGARFGGKGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKAGFCSLPTADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFLPDEITAMLRTVSAVLQFGNIVLKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGSHPKFQRPRHLRDQADFSVLHYAGKVDYKASEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQRRQQQQSALRVMQRNCAAYLKLRNWQWWRLFIKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQSRVAQLEEERSRLAEQLRAEAELCSEAEETRARLSARKQELELVVSELEARVGEEEECSRQLQGEKKRLQQHIQELESHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNAKLSKERRLLEERLSEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLKKEEKGRQELEKLKRRLDGESSELQEQMVEQKQRAEELLAQLGRKEDELQAALVRAEEEGGARAQLLKSLREAQAGLAEAQEDLETERAARAKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETHAHEVAMQELRQRHGQALGELAEQLEQARRGKGVWEKTRLTLEAEVTELRAELSSLRTSRQEGEQKRRRLESQLQEVQGRASDVDRARTEAAEKLQRAQAELESVSTALSEAESKAIRLGKELSSAESQLHDTQELLQEETRAKLALGSRVRALEAEAAGLREQMEEEVVARERAGRELQSAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAETLAQRLAEKTEAVERLERARRRLQQELDDATVDLGQQKQLLSTLEKKQRKFDQLLAEEKAAVLRAVEDRERVEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKNVHELERARRVAEQAANDLRTQVTELEDELTATEDAKLRLEVTVQALKAQHERDLQGRDDAGEERRKQLVKQLRDAEVERDEERKQRALAVAARKKLEAELEELKAQTSAAGQGKEEAVKQLRKMQVQMKELWREVEETRSSREEIFTLNKESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAEEVATGNLSKTAILEEKRQLEGRLGQLEEELEEEQNNSEILRDHYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELKSRLGEEDAGARARQKMLIAALESKLAQAEEQLEQESRERILSGKLVRRAEKRLKEVVLQVDEERRVADQLRDQLEKGNLRLKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEEAEGAERGPAPPQEPEAPSLATPQ", "length": 2020, "header": "tr|A0A9J7H517-1|A0A9J7H517_CRIGR Isoform 1 of Myosin-14 OS=Cricetulus griseus OX=10029 GN=Myh14 PE=3 SV=1 CANONICAL=A0A9J7H517-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H517-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H517/entry#A0A9J7H517-1", "sequence": { "sequence": "MAAVTLSVPGRKVAARAGPVPEAAQPFLFTPRTPNVGGPGGPQVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFVSKGTMRVAIWETGARFGGKGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKAGFCSLPTADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFLPDEITAMLRTVSAVLQFGNIVLKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGSHPKFQRPRHLRDQADFSVLHYAGKVDYKASEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQRRQQQQSALRVMQRNCAAYLKLRNWQWWRLFIKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQSRVAQLEEERSRLAEQLRAEAELCSEAEETRARLSARKQELELVVSELEARVGEEEECSRQLQGEKKRLQQHIQELESHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNAKLSKERRLLEERLSEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLKKEEKGRQELEKLKRRLDGESSELQEQMVEQKQRAEELLAQLGRKEDELQAALVRAEEEGGARAQLLKSLREAQAGLAEAQEDLETERAARAKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETHAHEVAMQELRQRHGQALGELAEQLEQARRGKGVWEKTRLTLEAEVTELRAELSSLRTSRQEGEQKRRRLESQLQEVQGRASDVDRARTEAAEKLQRAQAELESVSTALSEAESKAIRLGKELSSAESQLHDTQELLQEETRAKLALGSRVRALEAEAAGLREQMEEEVVARERAGRELQSAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAETLAQRLAEKTEAVERLERARRRLQQELDDATVDLGQQKQLLSTLEKKQRKFDQLLAEEKAAVLRAVEDRERVEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKNVHELERARRVAEQAANDLRTQVTELEDELTATEDAKLRLEVTVQALKAQHERDLQGRDDAGEERRKQLVKQLRDAEVERDEERKQRALAVAARKKLEAELEELKAQTSAAGQGKEEAVKQLRKMQVQMKELWREVEETRSSREEIFTLNKESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAEEVATGNLSKTAILEEKRQLEGRLGQLEEELEEEQNNSEILRDHYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELKSRLGEEDAGARARQKMLIAALESKLAQAEEQLEQESRERILSGKLVRRAEKRLKEVVLQVDEERRVADQLRDQLEKGNLRLKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEEAEGAERGPAPPQEPEAPSLATPQ", "length": 2020, "header": "tr|A0A9J7H517-1|A0A9J7H517_CRIGR Isoform 1 of Myosin-14 OS=Cricetulus griseus OX=10029 GN=Myh14 PE=3 SV=1 CANONICAL=A0A9J7H517-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H517", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H517" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H517", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H517" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770655", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770655", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H517", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H517" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H517", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H517" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H517", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H517" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H517", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H517" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H517", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H517" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H517", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H517" } ], "pmid": "" }, { "name": "myosin filament", "id": "GO:0032982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032982", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H517", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H517" } ], "pmid": "" }, { "name": "myosin II complex", "id": "GO:0016460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016460", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H517", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H517" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "actomyosin structure organization", "id": "GO:0031032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031032", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H517", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H517" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H517", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H517" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H517", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H517" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1762, "end_pos": 1764, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1791, "end_pos": 1793, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": 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Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303724", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303724" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H538", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H538" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "B4galnt2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H538", "locus": {} } ], "crossref": [ { "id": "A0A9J7H538", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H538", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00761", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00761", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760696", "url": "https://www.ncbi.nlm.nih.gov/gene/100760696", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760696", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760696", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H538", "url": "https://www.orthodb.org/?gene=A0A9J7H538", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15046", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15046", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15046:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15046:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303724", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303724", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H538", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H538", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H538-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H538-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIVGLAIVVFMFRSESLQAMFHSFQPEFLKPAPHVPALKLLPEKDLRNLFTYDGVWLFPKNQCDCNSGQLQRKYDFQGAYNKKDLPAVTARRQAEFEHFQRRKGLPRPPPILAPPKLPFGYPVHGVEVMPLHTILIPGLQYEGPYAPVYEVTLRASLGTLNTLADVPDNVVQGRGQKQLTISTSDKKLLGFILQYVTYTSTEYQLHKVDMVSLESKSSVAKFPVTINQPVVPKLYDPGPERKLRNLVTIATKTFLRPHKLKILLQSIRKYYPDLTVIVADDSKEPLEIKDDYMEYYLMPFGKGWFAGRNLAISQVTTKYVLWVDDDFFFDNNTKIEVLVDVLEKTELDVVGGSVQGNAFQFRLLLEQSENGDCLHQRWGGFQALDGFPRCVVTSGVVNFFLAHTDQLRRVGFDPRLQRVAHSEFFVDGLGSLLVGSCPDVSVQHQSHAPWSKDAEVAAMEKSYNTYRVNTNAQVQFKLALHYFKNHLQCST", "length": 491, "header": "tr|A0A9J7H538-1|A0A9J7H538_CRIGR Isoform 1 of Beta-1,4 N-acetylgalactosaminyltransferase 2 OS=Cricetulus griseus OX=10029 GN=B4galnt2 PE=3 SV=1 CANONICAL=A0A9J7H538-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H538-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H538/entry#A0A9J7H538-1", "sequence": { "sequence": "MIVGLAIVVFMFRSESLQAMFHSFQPEFLKPAPHVPALKLLPEKDLRNLFTYDGVWLFPKNQCDCNSGQLQRKYDFQGAYNKKDLPAVTARRQAEFEHFQRRKGLPRPPPILAPPKLPFGYPVHGVEVMPLHTILIPGLQYEGPYAPVYEVTLRASLGTLNTLADVPDNVVQGRGQKQLTISTSDKKLLGFILQYVTYTSTEYQLHKVDMVSLESKSSVAKFPVTINQPVVPKLYDPGPERKLRNLVTIATKTFLRPHKLKILLQSIRKYYPDLTVIVADDSKEPLEIKDDYMEYYLMPFGKGWFAGRNLAISQVTTKYVLWVDDDFFFDNNTKIEVLVDVLEKTELDVVGGSVQGNAFQFRLLLEQSENGDCLHQRWGGFQALDGFPRCVVTSGVVNFFLAHTDQLRRVGFDPRLQRVAHSEFFVDGLGSLLVGSCPDVSVQHQSHAPWSKDAEVAAMEKSYNTYRVNTNAQVQFKLALHYFKNHLQCST", "length": 491, "header": "tr|A0A9J7H538-1|A0A9J7H538_CRIGR Isoform 1 of Beta-1,4 N-acetylgalactosaminyltransferase 2 OS=Cricetulus griseus OX=10029 GN=B4galnt2 PE=3 SV=1 CANONICAL=A0A9J7H538-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304942", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304942" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H540", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113837157", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540", "locus": {} } ], "crossref": [ { "id": "A0A9J7H540", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H540", "database": "AlphaFoldDB", "categories": [] }, { "id": "113837157", "url": "https://www.ncbi.nlm.nih.gov/gene/113837157", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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"sequence": { "sequence": "MFQRGWQASTSVWPVNKDLIMEQGREVCYSCEESFMTDDKMMMRVGHGHFSEMKLAFHVPTVTCVAVKVLRMKKKNASLVEVSIMKSLQHPDIIKLFGMVQSRDTTYLMMEHTSQGDLRHILELGSLQESEARRLFTQILLAMQYCHANHIAHRDIKANNILLNCRGNAKLSGFDLAIKVTPGQKLRDFCSTLLYCAPELLLEKAYDGCAADIWSLGVLLFLMVVGHFPFQDSSSEGVRHQILAANVRIPEHVSRDIFNVIVKMLMIKPQRRPTIDQILMCPMIREGKPHSPPMFTQKQSGTVSRGIVSTMTVMGYKSEEIIDSLRNQNYKQVRATYPILQHQSPGGDCGHEATNSKEVSVTKEVTITKEEAITQQPTITQEEDMAHEVTMTLEKTMTKEMTMDDGVSMTQTESITEKETIIKHEDIIREATITMEETVAQLRTLTQERTITQEEAITPGQPEDALTRERTITQEETIIKHEDIILEATITMEETVAQLRTLTQERTITQEEAITHGQADHALTRERTITQEEAITHGQPEDALTRERTITQEETVINHDDFIQEAAIIMEETLVQLRTLTRERTIIQEEAITHGQPEVAGPASSGNRRSSAWKRAKKTMVNCLRHLCCCCLPPAKRRQDSCKTLAPKTRDPAVTHRSSSEEVQPQLRGL", "length": 670, "header": "tr|A0A9J7H540-1|A0A9J7H540_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=LOC113837157 PE=4 SV=1 CANONICAL=A0A9J7H540-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 181, "start_aa": "Thr", "end_pos": 181, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr181", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H540", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H540", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113837157", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837157", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H540", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540" } ], "pmid": "" }, { "name": "tau-protein kinase activity", "id": "GO:0050321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050321", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H540", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H540", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H540", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H540", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", 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"A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3E2-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7F9C4-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2M7I3-1", "A0A8C2N3I1-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A9J7JQZ1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A3L7I1E7-1", "A0A9J7GBL6-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", 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"A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "A0A9J7JYC5-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3HX91-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", "A0A8C2QND0-1", "G3HXQ8-1", "A0A8C2M0A2-1", "A0A9J7K2S5-1", "A0A8C2MMZ5-1", "A0A8C2QH69-1", "A0A8C2QL63-1", "A0A9J7K953-1", "A0A9J7JBH0-1", "A0A9J7FEY2-1", "A0A9J7FGD3-1", "A0A9J7FKM1-1", "A0A9J7JKJ1-1", "A0A9J7G3C1-1", "A0A9J7G180-1", "A0A9J7JTL3-1", "A0A9J7GFS3-1", "A0A9J7GQ42-1", "A0A9J7EZ53-1", "A0A9J7J5Z8-1", "A0A9J7F0G6-1", "A0A9J7FCC7-1", "A0A9J7EVK4-1", "A0A9J7K3S4-1", "A0A9J7GAF4-1", "A0A9J7GBF4-1", "A0A8C2MTI7-1", "A0A9J7J1N3-1", "A0A9J7F4P4-1", "A0A9J7JNU2-1", "A0A9J7H3M5-1", "A0A9J7JJV6-1", "A0A9J7GJE4-1", "A0A8C2LY52-1", "A0A9J7H8U3-1", "A0A9J7F821-1", "A0A8C2N185-1", "A0A9J7KFV8-1", "A0A8C2MQM0-1", "A0A8C2N310-1", "A0A9J7H6V8-1", "A0A9J7H2P9-1", "A0A9J7H4N5-1", "A0A3L7GPC7-1", "A0A9J7J6H1-1", "A0A3L7HV37-1", "A0A8C2LTZ7-1", "A0A9J7K7D8-1", "A0A9J7JXM2-1", "A0A8C2LDU9-1", "A0A8C2LTW4-1", "A0A9J7JAM4-1", "A0A9J7JRJ8-1", "A0A8C2QEB8-1", "A0A3L7HKC4-1", "A0A8C2LI14-1", "A0A8C2QDX9-1", "A0A9J7G1D9-1", "A0A9J7F985-1", "A0A9J7G270-1", "A0A9J7K1H4-1", "A0A8C2MCX3-1", "A0A8C2MEU5-1", "A0A8C2MFN1-1", "A0A8C2MMI4-1", "A0A9J7JAB2-1", "A0A9J7G969-1", "A0A8C2MQ42-1", "A0A8C2MR08-1", "A0A8C2MUQ5-1", "A0A9J7FZA7-1", "A0A8C2N3C9-1", "A0A8C2N6L4-1", "A0A8C2N9X1-1", "A0A8C2QHF9-1", "A0A8C2QI80-1", "A0A8C2QKP7-1", "A0A9J7FFS7-1", "A0A9J7FI14-1", "A0A9J7FJ23-1", "A0A9J7JLH7-1", "A0A8C2MH43-1", "A0A9J7FZ18-1", "A0A9J7G368-1", "A0A9J7G6S5-1", "A0A9J7H2T6-1", "A0A9J7H3N1-1", "A0A9J7H8L4-1", "A0A9J7JIW6-1", "A0A9J7JRI3-1", "A0A061ILI7-1", "A0A061HUS7-1", "A0A061HVM6-1", "A0A061I033-1", "A0A061I8L6-1", "A0A061I9F9-1", "A0A8C2MQS3-1", "A0A9J7F0Y2-1", "A0A9J7EZ49-1", "A0A8C2M6A3-1", "A0A8C2MQL9-1", "A0A8C2LY02-1", "A0A8C2LZT2-1", "A0A8C2M165-1", "A0A8C2M5G2-1", "A0A8C2M3Y9-1", "A0A8C2M5A7-1", "A0A8C2M9B6-1", "A0A8C2MBW2-1", "A0A9J7JYU7-1", "A0A8C2MJ02-1", "A0A8C2ML15-1", "A0A9J7JQD1-1", "A0A8C2MMQ4-1", "A0A8C2MQ73-1", "A0A9J7KE81-1", "A0A9J7JPE2-1", "A0A9J7F773-1", "A0A8C2L7R1-1", "A0A8C2LHE9-1", "A0A3L7I870-1", "A0A3L7IB60-1", "A0A3L7IBX6-1", "A0A3L7ID00-1", "A0A3L7IEL5-1", "A0A3L7IER1-1", "A0A8C2LC89-1", "A0A8C2LCN7-1", "A0A8C2LEI8-1", "A0A8C2LH99-1", "A0A9J7GAB0-1", "A0A8C2LK72-1", "A0A8C2LMC9-1", "A0A8C2LMJ0-1", "A0A9J7JQV6-1", "A0A8C2LPR4-1", "A0A8C2LQB2-1", "A0A8C2LVV5-1", "A0A8C2MYH0-1", "A0A8C2MV78-1", "A0A9J7JHJ2-1", "A0A8C2N0J6-1", "A0A8C2N210-1", "A0A8C2N457-1", "A0A8C2N4W2-1", "A0A8C2N756-1", "A0A8C2QGY5-1", "A0A8C2QJ34-1", "A0A8C2QJA4-1", "A0A9J7KDV7-1", "A0A8C2QNX2-1", "A0A8C2QPB0-1", "A0A9J7EVN3-1", "A0A9J7F0N6-1", "A0A8C2M6E6-1", "A0A9J7F2L0-1", "A0A9J7F3R3-1", "A0A9J7F5B0-1", "A0A8C2LDE5-1", "A0A9J7JB60-1", "A0A9J7F927-1", "A0A9J7F8V5-1", "A0A9J7F8T0-1", "A0A9J7FBT0-1", "A0A9J7FD79-1", "A0A9J7FLY5-1", "A0A9J7K2Q7-1", "A0A3L7I1R2-1", "A0A9J7FYY3-1", "A0A9J7GBI2-1", "A0A9J7FN68-1", "A0A9J7FNF0-1", "A0A9J7FS53-1", "A0A9J7FUL0-1", "A0A9J7FVR6-1", "A0A9J7FZH7-1", "A0A9J7FZW1-1", "A0A9J7G1H0-1", "A0A9J7G5F3-1", "A0A9J7G5N9-1", "A0A8C2LFT9-1", "A0A9J7G9D1-1", "A0A8C2MB66-1", "A0A9J7GD76-1", "A0A8C2LQS5-1", "A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GT89-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JIF8-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7F9C4-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A8C2M7I3-1", "A0A8C2MBI9-1", "A0A9J7JQZ1-1", "A0A8C2N3I1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7GBL6-1", "A0A9J7H8W5-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7H540-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H949-1", "A0A9J7GQY0-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] } ] }, { "uniprot_ac": "A0A8C2M3Y9", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] } ] }, { "uniprot_ac": "A0A8C2M497", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": 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"id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] } ] }, { "uniprot_ac": "A0A8C2QND0", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] } ] }, { "uniprot_ac": "A0A8C2QNX2", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A9J7EVK4", "gene_name": "Bmp2k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] } ] }, { "uniprot_ac": "A0A9J7EVN3", "gene_name": "LOC100754361", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] } ] }, { "uniprot_ac": "A0A9J7EXX8", "gene_name": "LOC113832238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] } ] }, { "uniprot_ac": "A0A9J7F0J6", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] } ] }, { "uniprot_ac": "A0A9J7F1D2", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1D2" } ] } ] }, { "uniprot_ac": "A0A9J7F2F1", "gene_name": "Prkcd", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ 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] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] } ] }, { "uniprot_ac": "A0A9J7G5N9", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": 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"https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] } ] }, { "uniprot_ac": "A0A9J7G9D1", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] } ] }, { "uniprot_ac": "A0A9J7GAB0", "gene_name": "Pkn3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] } ] }, { "uniprot_ac": "A0A9J7GAF4", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBI2", "gene_name": "LOC100771767", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] } ] }, { "uniprot_ac": "A0A9J7GBL6", "gene_name": "Ttbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] } ] }, { "uniprot_ac": "A0A9J7GD76", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] } ] }, { "uniprot_ac": "A0A9J7GES8", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] } ] }, { "uniprot_ac": "A0A9J7GF59", "gene_name": "LOC103160391", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] } ] }, { "uniprot_ac": "A0A9J7GIN7", "gene_name": "Eif2ak3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] } ] }, { "uniprot_ac": "A0A9J7GJE4", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] } ] }, { "uniprot_ac": "A0A9J7GK55", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] } ] }, { 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] } ] }, { "uniprot_ac": "A0A9J7GP29", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] } ] }, { "uniprot_ac": "A0A9J7GQ42", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] } ] }, { "uniprot_ac": "A0A9J7GQY0", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] } ] }, { "uniprot_ac": "A0A9J7GR05", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] } ] }, { "uniprot_ac": "A0A9J7GR29", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR29", "database": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H2E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H2E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2E9" } ] } ] }, { "uniprot_ac": "A0A9J7H2P9", "gene_name": "LOC113839030", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H2P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H2P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P9" } ] } ] }, { "uniprot_ac": "A0A9J7H2T6", "gene_name": "Ttn", "activity": [ { "ec_number": "2.7.11.1", "activity": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] } ] }, { "uniprot_ac": "A0A9J7H3M5", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] } ] }, { "uniprot_ac": "A0A9J7H3N1", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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{ "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", 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computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304010", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304010" } ] }, { "annotation": "Could be involved in calcium-dependent cell adhesion or intercellular interactions. 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This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304455" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JQL3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQL3#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A9J7H562", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H562#function" }, { "database": "UniProtKB", "id": "A0A9J7H892", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H892#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H892", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304455", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H562", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H562", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H562-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H562-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H892", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H892", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H892-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H892-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQL3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQL3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGAGDQGAGLRPHQHSGRPSGMESGLTGNGSGDGLVGIKQEKPEWQLQAVVSQASLPEKDKENIFLQPGGLPPCQTMGRPWALGSQEEVGGAWWAPPPEQDAGLEARVPGTAPGPLSPALSGGGGHFVCMDCGKRFSWWSSLKIHQRTHTGEKPYLCSKCGKSFSQKPNLERHQRHHTGERPFCCLECPRRFSQKQHLLKHQKTHTRPTTHPCPECERCFRHQVGLRIHLRVHARDRLGVHVSLHEMLPYAARRRRACRLRPGSPRGRPEWVWLGLYQGWWGQHKVRTAAHSRLCPSEQRQFICNECGKSFTWWSSLNIHQRIHTGERPYGCPECGRRFSQKPNLTRHLRNHTGERPHPCSHCGRSFRQKQHLLKHLRTHLPGGQAARCTSCGQNCPSRAALRAHQRMHAATELLRSRSAVQGGVPGSESQAETVQSVAVKPHGSQGAKKVPCGQGCETLAASSEQRQFICNECGKSFSWWSALTIHQRIHTGERPYACPDCGRCFSQKPNLTRHRRNHTGERPYLCTACGRGFRQKQHLLKHQRVHRGAQAPHPGPEEEEEPYMSDLRTPWRGPSFYSHWAQAQSAKPQLPAPSVWWP", "length": 600, "header": "tr|A0A9J7H892-1|A0A9J7H892_CRIGR Isoform 1 of Zinc finger protein 775 OS=Cricetulus griseus OX=10029 GN=Znf775 PE=3 SV=1 CANONICAL=A0A9J7H892-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H562-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H892/entry#A0A9J7H562-1", "sequence": { "sequence": "MAGAGDQGAGLRPHQHSGRPSGMESGLTGNGSGDGLVGIKQEKPEWQLQAVVSQASLPEKDKENIFLQPGGLPPCQTMGRPWALGSQEEVGGAWWAPPPEQDAGLEARVPGTAPGPLSPALSGGGGHFVCMDCGKRFSWWSSLKIHQRTHTGEKPYLCSKCGKSFSQKPNLERHQRHHTGERPFCCLECPRRFSQKQHLLKHQKTHTRPTTHPCPECERCFRHQVGLRIHLRVHARDRLGVHVSLHEMLPYAARRRRACRLRPGSPRGRPEWVWLGLYQGWWGQHKVRTAAHSRLCPSEQRQFICNECGKSFTWWSSLNIHQRIHTGERPYGCPECGRRFSQKPNLTRHLRNHTGERPHPCSHCGRSFRQKQHLLKHLRTHLPGGQAARCTSCGQNCPSRAALRAHQRMHAATELLRSRSAVQGGVPGSESQAETVQSVAVKPHGSQGAKKVPCGQGCETLAASSEQRQFICNECGKSFSWWSALTIHQRIHTGERPYACPDCGRCFSQKPNLTRHRRNHTGERPYLCTACGRGFRQKQHLLKHQRVHRGAQAPHPGPEEEEEP", "length": 564, "header": "tr|A0A9J7H562-1|A0A9J7H892_CRIGR Computationally mapped isoform of Zinc finger protein 775 OS=Cricetulus griseus OX=10029 GN=Znf775 PE=3 SV=1 CANONICAL=A0A9J7H892-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H892-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H892/entry#A0A9J7H892-1", "sequence": { "sequence": "MAGAGDQGAGLRPHQHSGRPSGMESGLTGNGSGDGLVGIKQEKPEWQLQAVVSQASLPEKDKENIFLQPGGLPPCQTMGRPWALGSQEEVGGAWWAPPPEQDAGLEARVPGTAPGPLSPALSGGGGHFVCMDCGKRFSWWSSLKIHQRTHTGEKPYLCSKCGKSFSQKPNLERHQRHHTGERPFCCLECPRRFSQKQHLLKHQKTHTRPTTHPCPECERCFRHQVGLRIHLRVHARDRLGVHVSLHEMLPYAARRRRACRLRPGSPRGRPEWVWLGLYQGWWGQHKVRTAAHSRLCPSEQRQFICNECGKSFTWWSSLNIHQRIHTGERPYGCPECGRRFSQKPNLTRHLRNHTGERPHPCSHCGRSFRQKQHLLKHLRTHLPGGQAARCTSCGQNCPSRAALRAHQRMHAATELLRSRSAVQGGVPGSESQAETVQSVAVKPHGSQGAKKVPCGQGCETLAASSEQRQFICNECGKSFSWWSALTIHQRIHTGERPYACPDCGRCFSQKPNLTRHRRNHTGERPYLCTACGRGFRQKQHLLKHQRVHRGAQAPHPGPEEEEEPYMSDLRTPWRGPSFYSHWAQAQSAKPQLPAPSVWWP", "length": 600, "header": "tr|A0A9J7H892-1|A0A9J7H892_CRIGR Isoform 1 of Zinc finger protein 775 OS=Cricetulus griseus OX=10029 GN=Znf775 PE=3 SV=1 CANONICAL=A0A9J7H892-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H892/entry#A0A9J7JQL3-1", "sequence": { "sequence": "MESGLTGNGSGDGLVGIKQEKPEWQLQAVVSQASLPEKDKENIFLQPGGLPPCQTMGRPWALGSQEEVGGAWWAPPPEQDAGLEARVPGTAPGPLSPALSGGGGHFVCMDCGKRFSWWSSLKIHQRTHTGEKPYLCSKCGKSFSQKPNLERHQRHHTGERPFCCLECPRRFSQKQHLLKHQKTHTRPTTHPCPECERCFRHQVGLRIHLRVHARDRLGVHVSLHEMLPYAARRRRACRLRPGSPRGRPEWVWLGLYQGWWGQHKVRTAAHSRLCPSEQRQFICNECGKSFTWWSSLNIHQRIHTGERPYGCPECGRRFSQKPNLTRHLRNHTGERPHPCSHCGRSFRQKQHLLKHLRTHLPGGQAARCTSCGQNCPSRAALRAHQRMHAATELLRSRSAVQGGVPGSESQAETVQSVAVKPHGSQGAKKVPCGQGCETLAASSEQRQFICNECGKSFSWWSALTIHQRIHTGERPYACPDCGRCFSQKPNLTRHRRNHTGERPYLCTACGRGFRQKQHLLKHQRVHRGAQAPHPGPEEEEEPYMSDLRTPWRGPSFYSHWAQAQSAKPQLPAPSVWWP", "length": 578, "header": "tr|A0A9J7JQL3-1|A0A9J7H892_CRIGR Computationally mapped isoform of Zinc finger protein 775 OS=Cricetulus griseus OX=10029 GN=Znf775 PE=3 SV=1 CANONICAL=A0A9J7H892-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JQL3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQL3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JQL3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQL3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773995", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773995", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H892", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H892" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H892", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H892" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H892", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H892" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H892", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H892" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H892", "url": 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H568", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H568" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766148", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766148", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H568", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H568" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mechanosensitive monoatomic ion channel activity", "id": "GO:0008381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008381", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H568", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H568" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H568" }, { "id": "PF07810", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07810" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TMC", "eco_id": "ECO_0000259", "start_pos": 564, "end_pos": 674, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], 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"url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305001" } ] } ], "protein_names": [ { "name": "Carcinoembryonic antigen-related cell adhesion molecule 3 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H569", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H569/entry#names_and_taxonomy" } ] }, { "name": "carcinoembryonic antigen-related cell adhesion molecule 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305001", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305001" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 15% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305001", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305001" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H569", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H569" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC107980387", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H569", "locus": {} } ], "crossref": [ { "id": "A0A9J7H569", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H569", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05774", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05774", "database": "CDD", "categories": [ "Protein 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"tr|A0A9J7H569-1|A0A9J7H569_CRIGR Isoform 1 of Carcinoembryonic antigen-related cell adhesion molecule 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC107980387 PE=3 SV=1 CANONICAL=A0A9J7H569-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H569-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H569/entry#A0A9J7H569-1", "sequence": { "sequence": "MAMPSVLLCNGCTPWQRLLFTASLLACWHFSTSTAQVTIESVPPQVVEGENVLFLVHNLPENLIASVWFRGLKITENVIAIYDLKQDFSAPGPIHSGRETVYRNGSLLLRNVTMKDTGRYTLRTINRHGDIVSTTIMNLHVHKHVMQPFLEISDATVAVEKSVSLICISPHDDNSFHWLFNNQSLQLTDRMTLTVTKRVLRIDPVRIEDAGDYQCEVSNPVSSKTSLPVRLAVVKG", "length": 236, "header": "tr|A0A9J7H569-1|A0A9J7H569_CRIGR Isoform 1 of Carcinoembryonic antigen-related cell adhesion molecule 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC107980387 PE=3 SV=1 CANONICAL=A0A9J7H569-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H569", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H569" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H569", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H569" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:107980387", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:107980387", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H569", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H569" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H569", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H569" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H569", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H569" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H569", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H569" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tyrosine kinase binding", "id": "GO:1990782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990782", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H569", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H569" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H569", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H569" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 148, "end_pos": 232, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 111, "end_pos": 113 }, { "start_pos": 182, "end_pos": 184 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H6C6-1", "uniprot_ac": "A0A9J7H6C6", "uniprot_id": "A0A9J7H6C6_CRIGR", "mass": { "chemical_mass": 144834.0, "monoisotopic_mass": 144834.0 }, "refseq": { "ac": "XP_035305766", "name": "trophinin isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305766" }, "gene_names": [ { "name": "Tro", "type": "recommended", "evidence": [ { "id": "A0A9J7H6C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C6" } ] }, { "name": "Tro", "type": "synonym", "evidence": [ { "id": "XP_035305766", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305766" } ] } ], "protein_names": [ { "name": "Melanoma-associated antigen D1", "type": "recommended", "evidence": [ { "id": "A0A9J7H6C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C6/entry#names_and_taxonomy" } ] }, { "name": "MAGE-D1 antigen", "type": "synonym", "evidence": [ { "id": "A0A9J7H6C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C6/entry#names_and_taxonomy" } ] }, { "name": "Neurotrophin receptor-interacting MAGE homolog", "type": "synonym", "evidence": [ { "id": "A0A9J7H6C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C6/entry#names_and_taxonomy" } ] }, { "name": "trophinin isoform X3", "type": "synonym", "evidence": [ { "id": "XP_035305766", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305766" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305766", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305766" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6C6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tro", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C6", "locus": {} } ], "crossref": [ { "id": "100759986", "url": "https://www.ncbi.nlm.nih.gov/gene/100759986", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759986", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759986", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H6C6", "url": "https://www.orthodb.org/?gene=A0A9J7H6C6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11736:SF83", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11736:SF83", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38634", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38634", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38634:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38634:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01454", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01454", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305766", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305766", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H577", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H577", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H577-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H577-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H640", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H640", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H640-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H640-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6C6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRRNDYGYRMPTFQGPLPPPGSLGLPFSSDVQTETTEKDNVLLMRTLLSTSKDTPIASRSKKSKTKKTSIKAITKTTPTPPPVPPANDIAGNKPKVTLQALNLPMFTQISQASSTTEAANIQASVTAQTKKAKTKRVTPKLSLNGTEDVTTQLKSPLKALNLPVTSPTIQSPIANESANSLALIAVSKPKKAPKAKKAANKTIPSATEISLASTATHTATTQGQTAKETASIQATAATIRAKKTSKAKRTTAKTTNTDTEYVESSNALEGSSRQIEASTVGLRPKKPKGKKVANKGPNSASELSEAPPAIQMVTNHALSVTVRIRRGSRARKAATKTRAQESQAQITDQGAQAKMATPQASISALETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHPNGEERTGSNYRRIPWGRRPPPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLKDVIQEYDEYFPEIIERASYALEKMFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACKVQKKDPKDWAAQYREAVEMDVQAAAVAVAEAEARAEARAQMGIGEEAVAGPWNWDDMDIDCLTREELGDDAQAWNRFSFEIDSRAQENADSTNNLNFNQGPSTRNSFSDGANISFGGITNPSGGFGGMPNSNASISFGSASSTSTSFSSGASISFGGAPNTSTSFSSTATISFGGAPSTNTSFSSTASISFGGAPSISSSFSGGSSISFGGSPSTSTSFSGGASISFGGAPCTSASFNGFGGTLSSTAAGFSGALSTSTNFGSAPTTSTVFSGAVSTTTGFGGTLSTSVCFGSSPCSGAGFGGTLSTSICFGGSPSTNNGFGGTLSTSVSFGASSSTSSDFGGTLSTSLCFGGAISTSAGFGNALSTSASFGSVLNGSSGFGGAISTSASFGNALNNSAGFGGAISTSASFGGALNGSSGFGGAISTSASFGGALNGSAGFGGAISTSASFGGALNGSAGFGGAISTSASFGGAISTSASFGGAISTNPDFGGAFSTSVGFGGALSTTDFGSTHSNSISFGSAPTTSVSFGSSHSTNLCFGGAPSNSLCFGSASNTNLCFGGSSSTNSCFSGATSANYSEGHSTSAIFSFGNGLSTNAGFGNGLGTSAGFGSSLGTSTDFGGGLSPNADFGGGLGTSAGFDGGLNTSTDFGGGLGTNAGFGDGLGSNTGFGGGLVTNDGFAGDLSANNGFGSTLGTGAGFGVSLSTGDGFGNGSNASFDRGLNTIIGFGSDSNTSSSFTGEPSTGSSFSNGPSSIVGFSGGPSTGAGFCNGPSTAGFGGGLSGSAGFGGGLNSSAGFSGGPSTGTGFGGGGTNLGACGFSYG", "length": 1436, "header": "tr|A0A9J7H6C6-1|A0A9J7H6C6_CRIGR Isoform 1 of Melanoma-associated antigen D1 OS=Cricetulus griseus OX=10029 GN=Tro PE=4 SV=1 CANONICAL=A0A9J7H6C6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H577-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C6/entry#A0A9J7H577-1", "sequence": { "sequence": "MDRRNDYGYRMPTFQGPLPPPGSLGLPFSSDVQTETTEKDNVLLMRTLLSTSKDTPIASRSKKSKTKKTSIKAITKTTPTPPPVPPANDIAGNKPKVTLQALNLPMFTQISQASSTTEAANIQASVTAQTKKAKTKRVTPKLSLNGTEDVTTQLKSPLKALNLPVTSPTIQSPIANESANSLALIAVSKPKKAPKAKKAANKTIPSATEISLASTATHTATTQGQTAKETASIQATAATIRAKKTSKAKRTTAKTTNTDTEYVESSNALEGSSRQIEASTVGLRPKKPKGKKVANKGPNSASELSEAPPAIQMVTNHALSVTVRIRRGSRARKAATKTRAQESQAQITDQGAQAKMATPQASISALETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHPNGEERTGSNYRRIPWGRRPPPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLKDVIQEYDEYFPEIIERASYALEKMFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACKVQKKDPKDWAAQYREAVEMDVQAAAVAVAEAEARAEARAQMGIGEEAVAGPWNWDDMDIDCLTREELGPSTRNSFSDGANISFGGITNPSGGFGGMPNSNGGFGGIPNSNGGFGGIPNSNGGFGGIPNSNGGFGGIPNSNGGFGGPSTGAGFGGPSTGGGFGGPSTAAGFGGGLSGSAGFGGGLNSSAGFSGGPSTGTGFGGGGTNLGACGFSYG", "length": 829, "header": "tr|A0A9J7H577-1|A0A9J7H6C6_CRIGR Computationally mapped isoform of Melanoma-associated antigen D1 OS=Cricetulus griseus OX=10029 GN=Tro PE=4 SV=1 CANONICAL=A0A9J7H6C6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H640-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C6/entry#A0A9J7H640-1", "sequence": { "sequence": "MDRRNDYGYRMPTFQSKHPNGEERTGSNYRRIPWGRRPPPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLKDVIQEYDEYFPEIIERASYALEKMFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACKVQKKDPKDWAAQYREAVEMDVQAAAVAVAEAEARAEARAQMGIGEEAVAGPWNWDDMDIDCLTREELGDDAQAWNRFSFEIDSRAQENADSTNNLNFNQGPSTRNSFSDGANISFGGITNPSGGFGGMPNSNASISFGSASSTSTSFSSGASISFGGAPNTSTSFSSTATISFGGAPSTNTSFSSTASISFGGAPSISSSFSGGSSISFGGSPSTSTSFSGGASISFGGAPCTSASFNGFGGTLSSTAAGFSGALSTSTNFGSAPTTSTVFSGAVSTTTGFGGTLSTSVCFGSSPCSGAGFGGTLSTSICFGGSPSTNNGFGGTLSTSVSFGASSSTSSDFGGTLSTSLCFGGAISTSAGFGNALSTSASFGSVLNGSSGFGGAISTSASFGNALNNSAGFGGAISTSASFGGALNGSSGFGGAISTSASFGGALNGSAGFGGAISTSASFGGALNGSAGFGGAISTSASFGGAISTSASFGGAISTNPDFGGAFSTSVGFGGALSTTDFGSTHSNSISFGSAPTTSVSFGSSHSTNLCFGGAPSNSLCFGSASNTNLCFGGSSSTNSCFSGATSANYSEGHSTSAIFSFGNGLSTNAGFGNGLGTSAGFGSSLGTSTDFGGGLSPNADFGGGLGTSAGFDGGLNTSTDFGGGLGTNAGFGDGLGSNTGFGGGLVTNDGFAGDLSANNGFGSTLGTGAGFGVSLSTGDGFGNGSNASFDRGLNTIIGFGSDSNTSSSFTGEPSTGSSFSNGPSSIVGFSGGPSTGAGFCNGPSTAGFGGGLSGSAGFGGGLNSSAGFSGGPSTGTGFGGGGTNLGACGFSYG", "length": 1051, "header": "tr|A0A9J7H640-1|A0A9J7H640_CRIGR Computationally mapped isoform of Melanoma-associated antigen D1 OS=Cricetulus griseus OX=10029 GN=Tro PE=4 SV=1 CANONICAL=A0A9J7H6C6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H6C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C6/entry#A0A9J7H6C6-1", "sequence": { "sequence": 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This record is derived from a genomic sequence (NW_003613637.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035294057", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294057" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H582", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H582" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100751701", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H582", "locus": {} } ], "crossref": [ { "id": "A0A9J7H582", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H582", "database": "AlphaFoldDB", "categories": [] }, { "id": "100751701", "url": "https://www.ncbi.nlm.nih.gov/gene/100751701", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751701", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751701", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H582", "url": "https://www.orthodb.org/?gene=A0A9J7H582", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15123", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15123", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15123:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15123:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_035294057", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294057", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H582", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H582", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H582-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H582-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVAYSVTSTGPCPRILWTLLLLAASLNAHTQTWDNPTCTESEVSAPRGNRVVMACNISNTFRDVTIGLTANGKTSTIFNTKPPGNYFNDSWQLQIQGGQAYLVITDVQDIHAGQYVWRLNGNQRPPDQFIVLNVTDPDTEDQEPESLQVIAEPPPAVHTDVTIVMIIIIIIIVVVVIIGIIAFAWYKHYGSRKHHRYEVPGPGLSPGSPHSPYLALP", "length": 217, "header": "tr|A0A9J7H582-1|A0A9J7H582_CRIGR Isoform 1 of Secreted and transmembrane protein 1b-like OS=Cricetulus griseus OX=10029 GN=LOC100751701 PE=4 SV=1 CANONICAL=A0A9J7H582-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H582-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H582/entry#A0A9J7H582-1", "sequence": { "sequence": "MVAYSVTSTGPCPRILWTLLLLAASLNAHTQTWDNPTCTESEVSAPRGNRVVMACNISNTFRDVTIGLTANGKTSTIFNTKPPGNYFNDSWQLQIQGGQAYLVITDVQDIHAGQYVWRLNGNQRPPDQFIVLNVTDPDTEDQEPESLQVIAEPPPAVHTDVTIVMIIIIIIIVVVVIIGIIAFAWYKHYGSRKHHRYEVPGPGLSPGSPHSPYLALP", "length": 217, "header": "tr|A0A9J7H582-1|A0A9J7H582_CRIGR Isoform 1 of Secreted and transmembrane protein 1b-like OS=Cricetulus griseus OX=10029 GN=LOC100751701 PE=4 SV=1 CANONICAL=A0A9J7H582-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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isoform X2 OS=Cricetulus griseus OX=10029 GN=Pla2g4c PE=4 SV=1 CANONICAL=A0A9J7H5B5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5B5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5B5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5B5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5B5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754559", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754559", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5B5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5B5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5B5", "url": 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"end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" }, { "start_pos": 739, "end_pos": 741, "annotation": "n_glycosylation_sequon" }, { "start_pos": 839, "end_pos": 841, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15801", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7GN25-1", "G3GWV5-1", "G3HKV9-1", "G3HU37-1", "G3I6R7-1", "G3I3H3-1", "G3H0N8-1", "A0A9J7EWD9-1", "A0A9J7FZ00-1", "A0A9J7FZ10-1", "A0A9J7FZ67-1", "A0A9J7JIA7-1", "A0A9J7JN73-1", "A0A9J7JR59-1", "A0A061IDH0-1", "A0A8C2M3H3-1", "A0A9J7K9A2-1", "A0A9J7G6Q5-1", "A0A9J7G6Z0-1", "A0A3L7I2I8-1", "A0A9J7JL35-1", "A0A061IFI5-1", "A0A8C2LJA1-1", "A0A8C2LLB0-1", "A0A9J7FGH3-1", "A0A9J7G9Q8-1", "A0A9J7J6R6-1", "A0A3L7I8N6-1", "A0A8C2LBB3-1", "A0A8C2LXP3-1", "A0A8C2LZI5-1" ], "evidence": [ { "id": "15801", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15801" } ] }, { "id": "40427", "name": "", "equation": "1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GWV5-1", "G3I6R7-1", "G3H0N8-1", "A0A9J7EWD9-1", "A0A9J7FZ00-1", "A0A9J7FZ10-1", "A0A9J7FZ67-1", "A0A9J7JIA7-1", "A0A9J7JN73-1", "A0A9J7JR59-1", "A0A9J7K9A2-1", "A0A9J7G6Z0-1", "A0A9J7G6Q5-1", "A0A3L7I2I8-1", "A0A9J7JL35-1", "A0A9J7FGH3-1", "A0A8C2LZI5-1" ], "evidence": [ { "id": "40427", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40427" } ] }, { "id": "40435", "name": "", "equation": "1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + hexadecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GWV5-1", "G3HKV9-1", "G3H0N8-1", "A0A3L7I8J4-1", "A0A8C2MCD7-1", "A0A9J7K9A2-1", "A0A9J7FM40-1", "A0A9J7JI58-1", "A0A9J7G7U0-1", "A0A9J7G6Q5-1", "A0A9J7G6Z0-1", "A0A3L7I2I8-1", "A0A9J7JL35-1", "A0A9J7FGH3-1", "A0A9J7G8F0-1", "A0A9J7G9Q8-1", "A0A9J7JFH6-1" ], "evidence": [ { "id": "40435", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40435" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061IDH0", "gene_name": "Pla2g2e", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": 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"id": "A0A8C2LBB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LBB3" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "A0A8C2LBB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LBB3" } ] } ] }, { "uniprot_ac": "A0A8C2LJA1", "gene_name": "Abhd3", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8C2LJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA1" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8C2LJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA1" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A8C2LJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA1" } ] }, { "ec_number": "3.1.1.32", "activity": "", "evidence": [ { "id": "A0A8C2LJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA1" } ] } ] }, { "uniprot_ac": "A0A8C2LLB0", "gene_name": "Pla2g10", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8C2LLB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLB0" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A8C2LLB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLB0" } ] } ] }, { "uniprot_ac": "A0A8C2LXP3", "gene_name": "Pla2g2d", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": 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fatty acid + H(+).", "evidence": [ { "id": "A0A8C2M3H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3H3" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A8C2M3H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3H3" } ] } ] }, { "uniprot_ac": "A0A8C2MCD7", "gene_name": "Lypla1", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0A8C2MCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCD7" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0A8C2MCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCD7" } ] } ] }, { "uniprot_ac": "A0A9J7EWD9", "gene_name": "Pla2g3", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7EWD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EWD9" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7EWD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EWD9" } ] } ] }, { "uniprot_ac": "A0A9J7FGH3", "gene_name": "Pla2g6", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] } ] }, { "uniprot_ac": "A0A9J7FM40", "gene_name": "LOC100764608", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0A9J7FM40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FM40" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0A9J7FM40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FM40" } ] } ] }, { "uniprot_ac": "A0A9J7FZ00", "gene_name": "LOC100765177", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7FZ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ00" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7FZ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ00" } ] } ] }, { "uniprot_ac": "A0A9J7FZ10", "gene_name": "LOC113835677", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7FZ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ10" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7FZ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ10" } ] } ] }, { "uniprot_ac": "A0A9J7FZ67", "gene_name": "LOC100766341", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7FZ67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ67" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7FZ67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ67" } ] } ] }, { "uniprot_ac": "A0A9J7G6Q5", "gene_name": "Pla2g4e", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G6Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q5" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7G6Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q5" } ] } ] }, { "uniprot_ac": "A0A9J7G6Z0", "gene_name": "Pla2g4d", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G6Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7G6Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" } ] } ] }, { "uniprot_ac": "A0A9J7G7U0", "gene_name": "Pnpla7", "activity": [ { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G7U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7U0" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A9J7G7U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7U0" } ] } ] }, { "uniprot_ac": "A0A9J7G8F0", "gene_name": "Cel", "activity": [ { "ec_number": "3.1.1.-", "activity": "", "evidence": [ { "id": "A0A9J7G8F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F0" } ] } ] }, { "uniprot_ac": "A0A9J7G9Q8", "gene_name": "Plb1", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] } ] }, { "uniprot_ac": "A0A9J7GN25", "gene_name": "Pla2g5", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7GN25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GN25" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7GN25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GN25" } ] } ] }, { "uniprot_ac": "A0A9J7J6R6", "gene_name": "Pnpla3", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] } ] }, { "uniprot_ac": "A0A9J7JFH6", "gene_name": "Lipc", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] }, { "ec_number": "3.1.1.32", "activity": "", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] } ] }, { "uniprot_ac": "A0A9J7JI58", "gene_name": "Pnpla6", "activity": [ { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI58" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A9J7JI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI58" } ] } ] }, { "uniprot_ac": "A0A9J7JIA7", "gene_name": "LOC100763432", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JIA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIA7" } ] }, { "ec_number": "3.1.1.4", "activity": "", 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302871", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302871" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100753702", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J3", "locus": {} } ], "crossref": [ { "id": "100753702", "url": "https://www.ncbi.nlm.nih.gov/gene/100753702", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753702", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753702", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H5J3", "url": "https://www.orthodb.org/?gene=A0A9J7H5J3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31431", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31431", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31431:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31431:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10487", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10487", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302871", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302871", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H5J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JW67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JW67-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAGGPCVRSSRELWTILLGRSALRELSQIEAELNKYWQRLLEGLSYYKPPSSSSAERVKANKDVASPLKELGLRISKFLGLDEEQSVQLLQCYLQEDYRGTRDALKTVLQDERQSQALTLKIADYYYEERTCILRCVLHLLTYFQDERHPYRAEYADCVDKLEKELVLKYRQQFEELYRMEAPTWETHGNLMTERQVSRWFVQCLREQSMLLEIIFLYYAYFEMSPNDLLILTKMFKDQGFGSRQTNRHLVDETMDPFVDRIGYFSALILVEGMDIESLHKCALDDRRELHQFAQDGLVCQDMDRVMLTLGDIPHHAPVLLAWALLRHTLNPEETSSVVRKIGGTAIQLNVFQYLTRLLRSLASGGNDCTTSTACMCVYGLLSFALTSLELHTLGNQQDVIDTACEVLADPSLPELFWGTEPTSGLGIILDSVCGMFPHLLSPLLQLLRALVSGKSTAKKVYSFLDKMSFYNELHKHKPHDVLSHEDGTLWRRQTPKLLYPLGGQTNLRIPQGTVGQVMLDDRAYLVRWEYSYSSWTLFTCEIEMLLHVVSTADVIQHCQRVKPIIDLVHKVISTDLSIADCLLPITSRIYMLLQRLTTVISPPVNVIASCVNCLTVLAARNPAKVWTDLRHTGFLPFVAHPVSNMSQMISAEGMNAGGYGNLLMNSEQPQGEYGVTVAFLRLVTTLVKGQLGSTQSQGLVPCVMFVLKEMLPSYHKWRYNSHGVRELIGCLILELIHAILNLCQETDLHSSHTPSLPSLCICSLAYTEAGQTVISIMGIGVDTIDMVMAAQPRSDGPEGQGQGQLLIKTVKLAFSVTNNVIRLKPPSNVVSPLEQALTQHGAHGNNLIAVLAKYIYHRHDPALPRLAIQLLKRLATILSSWNSSVLFCRTLLEFFGTWSPKPVCCGLQVAPMSVYACLGSDAAAIRDAFLTRLQSKIEDMRIKVMILEFLTVAVETQPGLIELFLNLEVKDGSDGSKEFSLGVWSCLHVVLELIDSQQQDRYWCPPLLHRAAIAFLHALWQDRRDSAMLVLRTKPKFWENLTSPLFGTLSPPSETSEPSILETCALIMKIICLEIYYVVKGSLDQSLKDTLKKFSSEKRFAYWSGYVKSLAVYMAETEGSSCTSLLEYQMLVSAWRMLLIIATSHADIMHLTDVAVRRQLFLDVLDGTKALLLVSTSVNCLRLGSMMCTLLLILLRQWKRELGAVDKILGPLTEVLEGVLQADQQLMEKTKAKVFSAFITVLQMKEMRVSEIPQYSQLVLNVCETLQEEVIALFDQTRHSLASGSAAEDKDSMETDDCPRPRHKDQRDGVCVLGLHLAKELCEVDEDGDSWLQVTRRLPILPTLLTTLEVSLRMKQNLHFTEAALHLLLTLARTQQGATAVAGAGITQSICLPLLSVYQLSSNGTGQAPSTSRKSLDAPSWPGVYRLSMSLMERLLKTLRYNFLTEALDFVGVHQERTLQCLNAVRTVQSLACLEEADHTVGFILQLSHFRKEWHFHLPQLMRDVQVNLGYLCQACTSLLHSRKMLQHYLQNKNGDGLPSAVTPRVHRPATTTTTTTTTTTTVLAVPSACSSKQPVADTEASEQRALHTVQYGLLKILSRTLAALRHFTPDVCQILLDQSLDLAEYNFLFALSFTTPTFDSEVAPSFGTLLATVNVALNMLGELDKKKESLTQAVGLSTQAEGTRTLKSLLMFTMENCFYLLISQAVRYLRDPAVHPRDKQRMKQELSSELSTLLSSLSRYFRRGTPSSPAAGVLPSPQGKATSLSKASPESQEPLIQLVHAFVRHVQR", "length": 1793, "header": "tr|A0A9J7H5J3-1|A0A9J7H5J3_CRIGR Isoform 1 of Nucleoporin NUP188 OS=Cricetulus griseus OX=10029 GN=LOC100753702 PE=3 SV=1 CANONICAL=A0A9J7H5J3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H5J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J3/entry#A0A9J7H5J3-1", "sequence": { "sequence": "MAAAAGGPCVRSSRELWTILLGRSALRELSQIEAELNKYWQRLLEGLSYYKPPSSSSAERVKANKDVASPLKELGLRISKFLGLDEEQSVQLLQCYLQEDYRGTRDALKTVLQDERQSQALTLKIADYYYEERTCILRCVLHLLTYFQDERHPYRAEYADCVDKLEKELVLKYRQQFEELYRMEAPTWETHGNLMTERQVSRWFVQCLREQSMLLEIIFLYYAYFEMSPNDLLILTKMFKDQGFGSRQTNRHLVDETMDPFVDRIGYFSALILVEGMDIESLHKCALDDRRELHQFAQDGLVCQDMDRVMLTLGDIPHHAPVLLAWALLRHTLNPEETSSVVRKIGGTAIQLNVFQYLTRLLRSLASGGNDCTTSTACMCVYGLLSFALTSLELHTLGNQQDVIDTACEVLADPSLPELFWGTEPTSGLGIILDSVCGMFPHLLSPLLQLLRALVSGKSTAKKVYSFLDKMSFYNELHKHKPHDVLSHEDGTLWRRQTPKLLYPLGGQTNLRIPQGTVGQVMLDDRAYLVRWEYSYSSWTLFTCEIEMLLHVVSTADVIQHCQRVKPIIDLVHKVISTDLSIADCLLPITSRIYMLLQRLTTVISPPVNVIASCVNCLTVLAARNPAKVWTDLRHTGFLPFVAHPVSNMSQMISAEGMNAGGYGNLLMNSEQPQGEYGVTVAFLRLVTTLVKGQLGSTQSQGLVPCVMFVLKEMLPSYHKWRYNSHGVRELIGCLILELIHAILNLCQETDLHSSHTPSLPSLCICSLAYTEAGQTVISIMGIGVDTIDMVMAAQPRSDGPEGQGQGQLLIKTVKLAFSVTNNVIRLKPPSNVVSPLEQALTQHGAHGNNLIAVLAKYIYHRHDPALPRLAIQLLKRLATILSSWNSSVLFCRTLLEFFGTWSPKPVCCGLQVAPMSVYACLGSDAAAIRDAFLTRLQSKIEDMRIKVMILEFLTVAVETQPGLIELFLNLEVKDGSDGSKEFSLGVWSCLHVVLELIDSQQQDRYWCPPLLHRAAIAFLHALWQDRRDSAMLVLRTKPKFWENLTSPLFGTLSPPSETSEPSILETCALIMKIICLEIYYVVKGSLDQSLKDTLKKFSSEKRFAYWSGYVKSLAVYMAETEGSSCTSLLEYQMLVSAWRMLLIIATSHADIMHLTDVAVRRQLFLDVLDGTKALLLVSTSVNCLRLGSMMCTLLLILLRQWKRELGAVDKILGPLTEVLEGVLQADQQLMEKTKAKVFSAFITVLQMKEMRVSEIPQYSQLVLNVCETLQEEVIALFDQTRHSLASGSAAEDKDSMETDDCPRPRHKDQRDGVCVLGLHLAKELCEVDEDGDSWLQVTRRLPILPTLLTTLEVSLRMKQNLHFTEAALHLLLTLARTQQGATAVAGAGITQSICLPLLSVYQLSSNGTGQAPSTSRKSLDAPSWPGVYRLSMSLMERLLKTLRYNFLTEALDFVGVHQERTLQCLNAVRTVQSLACLEEADHTVGFILQLSHFRKEWHFHLPQLMRDVQVNLGYLCQACTSLLHSRKMLQHYLQNKNGDGLPSAVTPRVHRPATTTTTTTTTTTTVLAVPSACSSKQPVADTEASEQRALHTVQYGLLKILSRTLAALRHFTPDVCQILLDQSLDLAEYNFLFALSFTTPTFDSEVAPSFGTLLATVNVALNMLGELDKKKESLTQAVGLSTQAEGTRTLKSLLMFTMENCFYLLISQAVRYLRDPAVHPRDKQRMKQELSSELSTLLSSLSRYFRRGTPSSPAAGVLPSPQGKATSLSKASPESQEPLIQLVHAFVRHVQR", "length": 1793, "header": "tr|A0A9J7H5J3-1|A0A9J7H5J3_CRIGR Isoform 1 of Nucleoporin NUP188 OS=Cricetulus griseus OX=10029 GN=LOC100753702 PE=3 SV=1 CANONICAL=A0A9J7H5J3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JW67-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J3/entry#A0A9J7JW67-1", "sequence": { "sequence": "MAAAAGGPCVRSSRELWTILLGRSALRELSQIEAELNKYWQRLLEGLSYYKPPSSSSAERVKANKDVASPLKELGLRISKFLGLDEEQSVQLLQCYLQEDYRGTRDALKTVLQDERQSQALTLKIADYYYEERTCILRCVLHLLTYFQDERHPYRAEYADCVDKLEKELVLKYRQQFEELYRMEAPTWETHGNLMTERQVSRWFVQCLREQSMLLEIIFLYYAYFEMSPNDLLILTKMFKDQGFGSRQTNRHLVDETMDPFVDRIGYFSALILVEGMDIESLHKCALDDRRELHQFAQDGLVCQDMDRVMLTLGDIPHHAPVLLAWALLRHTLNPEETSSVVRKIGGTAIQLNVFQYLTRLLRSLASGGNDCTTSTACMCVYGLLSFALTSLELHTLGNQQDVIDTACEVLADPSLPELFWGTEPTSGLGIILDSVCGMFPHLLSPLLQLLRALVSGKSTAKKVYSFLDKMSFYNELHKHKPHDVLSHEDGTLWRRQTPKLLYPLGGQTNLRIPQGTVGQVMLDDRAYLVRWEYSYSSWTLFTCEIEMLLHVVSTADVIQHCQRVKPIIDLVHKVISTDLSIADCLLPITSRIYMLLQRLTTVISPPVNVIASCVNCLTVLAARNPAKVWTDLRHTGFLPFVAHPVSNMSQMISAEGMNAGGYGNLLMNSEQPQGEYGVTVAFLRLVTTLVKGQLGSTQSQGLVPCVMFVLKEMLPSYHKWRYNSHGVRELIGCLILELIHAILNLCQETDLHSSHTPSLPSLCICSLAYTEAGQTVISIMGIGVDTIDMVMAAQPRSDGPEGQGQGQLLIKTVKLAFSVTNNVIRLKPPSNVVSPLEQALTQHGAHGNNLIAVLAKYIYHRHDPALPRLAIQLLKRLATVAPMSVYACLGSDAAAIRDAFLTRLQSKIEDMRIKVMILEFLTVAVETQPGLIELFLNLEVKDGSDGSKEFSLGVWSCLHVVLELIDSQQQDRYWCPPLLHRAAIAFLHALWQDRRDSAMLVLRTKPKFWENLTSPLFGTLSPPSETSEPSILETCALIMKIICLEIYYVVKGSLDQSLKDTLKKFSSEKRFAYWSGYVKSLAVYMAETEGSSCTSLLEYQMLVSAWRMLLIIATSHADIMHLTDVAVRRQLFLDVLDGTKALLLVSTSVNCLRLGSMMCTLLLILLRQWKRELGAVDKILGPLTEVLEGVLQADQQLMEKTKAKVFSAFITVLQMKEMRVSEIPQYSQLVLNVCETLQEEVIALFDQTRHSLASGSAAEDKDSMETDDCPRPRHKDQRDGVCVLGLHLAKELCEVDEDGDSWLQVTRRLPILPTLLTTLEVSLRMKQNLHFTEAALHLLLTLARTQQGATAVAGAGITQSICLPLLSVYQLSSNGTGQAPSTSRKSLDAPSWPGVYRLSMSLMERLLKTLRYNFLTEALDFVGVHQERTLQCLNAVRTVQSLACLEEADHTVGFILQLSHFRKEWHFHLPQLMRDVQVNLGYLCQACTSLLHSRKMLQHYLQNKNGDGLPSAVTPRVHRPATTTTTTTTTTTTVLAVPSACSSKQPVADTEASEQRALHTVQYGLLKILSRTLAALRHFTPDVCQILLDQSLDLAEYNFLFALSFTTPTFDSEVAPSFGTLLATVNVALNMLGELDKKKESLTQAVGLSTQAEGTRTLKSLLMFTMENCFYLLISQAVRYLRDPAVHPRDKQRMKQELSSELSTLLSSLSRYFRRGTPSSPAAGVLPSPQGKATSLSKASPESQEPLIQLVHAFVRHVQR", "length": 1761, "header": "tr|A0A9J7JW67-1|A0A9J7H5J3_CRIGR Computationally mapped isoform of Nucleoporin NUP188 OS=Cricetulus griseus OX=10029 GN=LOC100753702 PE=3 SV=1 CANONICAL=A0A9J7H5J3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1547, "start_aa": "Thr", "end_pos": 1547, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1547", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JW67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW67" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JW67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW67" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753702", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753702", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J3" } ], "pmid": "" }, { "name": "RNA export from nucleus", "id": "GO:0006405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006405", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J3" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear pore inner ring", "id": "GO:0044611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044611", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1044, "end_pos": 1046, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1407, "end_pos": 1409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 648, "end_pos": 650, "annotation": "n_glycosylation_sequon" }, { "start_pos": 886, "end_pos": 888, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H5J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J3" }, { "id": "PF10487", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10487" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleoporin Nup188 N-terminal", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 480, "start_aa": "Gln", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H5J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5J3" }, { "id": "PF21093", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21093" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleoporin Nup188 N-terminal subdomain III", "eco_id": "ECO_0000259", "start_pos": 529, "end_pos": 887, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1547 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1044, "end_pos": 1046 }, { "start_pos": 1407, "end_pos": 1409 }, { "start_pos": 648, "end_pos": 650 }, { "start_pos": 886, "end_pos": 888 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases internal stop codons :: corrected 2 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304067", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304067" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dnah17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N7", "locus": {} } ], "crossref": [ { "id": "100768695", "url": "https://www.ncbi.nlm.nih.gov/gene/100768695", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013602", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013602", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035706", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035706", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768695", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768695", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H5N7", "url": "https://www.orthodb.org/?gene=A0A9J7H5N7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45703", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45703", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45703:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45703:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08393", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08393", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12774", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12774", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12775", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12775", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12781", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12781", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17852", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17852", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18198", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18199", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18199", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304067", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304067", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H5N7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPDARLDYLENVSFIVLKYKADKWGKLIGAEENMAMLTEFFDKADIPVLVLTLNPAGMIVPCLGFPETLKSKGLYFIKTKPENVTKDNYKTRLLFGDISPTPVEQLIAVVEEVLYSLLNQSENMNGWPRVVSEDIVKQVHRLKNEMFVMGGKVKGKTLLPIPEHLGSLDGTLESMERIPSTLDNSLLHSIETIIIDWSHQIRDVLSKDSAQALLDGLHPLPRVEFDFWDARLMNLRCIHEQLNRPKVNKIVEILEKAKSCYWPALQNVYMNVTQGLKEASDIVLYLKPLRILLDEMEQADFTVLPNFIVKVLSTICFIWATSEHYNTPSRVIVILREFSNQIIEMTRTYLSPEEVLKGLQGEIEEVLFGISLSVGVLKELFHAYDFCCANMKIFFKDKTPVPWEFPSSLAFSRMNSFFHRVQTIEDLYKTAIEFLKLEKIEVGGVRGNILGNLVTQIYDEVFDLVKVFAECKYDPLDPGDSSFDDDYKDFETKIQDLDRRLATIFCQAFDDCSSIESAAKLLYMCGGLLERPLILVEVVPRYSVLLEMFNNELDNAKLMYDAQMAASAQGQIPPIHKNMSSVAGQLKWSLELQERLEVSMRHLKHIEHPVMSSVEAKLVYEKYDEMMELLKGSREKIYQQWVAGVDQDCHFNLGQPLIQRDPYSNLIQVNFSKALVAVLREVKYLTFQHQKEIPTSAETLFSENETFRKFVGNLELIVGWYNEIKTTVMEVEFPLIKLELEEIDIKLLSAETTLFWNGENVFQYIQEMREVLYNLQNRIQKAKQNVEGITQAMQEWSANPLFERKDNKKEALLDLDGRVANLNKRYAAVKDAGVRIQAMVAENAELFRADTTSQPWKDYVNYIDSMVLDEFDHFIRKSLTYLMDNMTMDESIAPLFEIRMELDEEGLTYNPSLEMGEEGGFLMLIEGLINDLYNVARLIPRLAKGRINYKTDLEDITDLIEMREEVSNLVIGAMKVAEEYQDSFERYSYLWVDDLQESMKNFLIFGHTPTPEELDTRVDDTIPKTPPSLAQFQQQIDSYEKLYEEVSRCENTKVFHGWLQCDCRPFKQALLNTIKRWSFLFKRYLSNHVTNSLDDLENFMTVTRSGLKKPLKEGDYDGLVEVMGHLMKVKERQVATDSMFEPLKQTIELLKSYGEEMPEETHLKLQELPEKWTHTKKLAIQVKQNVSPLQANEVNILRRKCQQFELKQHEFREKFRREAPFSFSDPEPYKSLNKQQKSISAMESVMEALCKSAGLFEVTVPDYKQLKACHKEVRLLKELWDMIVMVNTSIDDWKTTKWKDINVEQMDIDCKKFAKDVRSLDKEMKTWDAFVGLDNTVKNMITSLRAVSELQNPAIRDRHWQQLMQATQVKFEMSEETTLADLLQLNLHKYEDEVRNIVDKAVKESGMEKILKALDSTWTTMEFEHEPHPRTGTMMLKSDEVLVETLEDNQVQLQNLMMSKYLSHFLKEVTSWQQKLSTADSVISIWFEVQRTWGHLESIFIGSEDIRAQLPEDSKRFDGIDQEFKALMADAVKTPNVVEATNKPGLYDKLEMLKKSLAVCEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASGQPVKIGLGMYSKEDEFVDFDRECDLSGQVEVWLNRVLDRMCATLRHEIPEAVVTYEEKPREQWIFDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIKDYNKKQISQLNALITLLIGNLSPGDRMKIMTICTIDVHARDVVAKMITAKVESSQAFTWQSQLRHRWDEEKKHCFANICDAQIQYSYEYLGNTPRLVITPLTDRXGPDTHPSAPHTSLGQVSGPPEGTDRNLLPAGLWKSLPPSDTSLSFSSXSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKKFNFLGEIISLIPTVGIFITMNPGYAGRTELPENLKALFRPCAMVVPDFELICEIMLVAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPTRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIIELKLQAEDSFVLKVVQLEELLQVRHSVFVIGNAGSGKSQVLKSLNKTYQNMKRKPVAVDLDPKAVTCDELFGIINPATREWKDGLFSTIMRDLANITHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLTILFDKYLPTCLDKLRVGFKRITPVPEITIIQTILYLLECLLTEKNAPPDSPKELYELYFVFACFWAFGGAMFQDQLIDYRVEFSRWWINEFKTIKLPSQGTIFDYYIDPETKKFMPWTDKVPAFELDPDVPLQASLVHTTETIRIRYFMDLLMAKAWPVMLVGNAGTGKSVLMGDKLESLGTDDYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLIYFIDDMNMPEVDKYGTVAPHTLIRQHMDHGHWYDRQKLTLKDVHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALITIYNTILAQHLSYRSTPLVIQRLSNQLVNAALALHQKIASTFLPTAIKFHYIFNLRDLSNIFQGILFSLAEILRTPLDLVRLWLHEAERVYGDKMVDDKDQETLRRVTMASTKKFFDDLGEEHIFARPNIFCHFAQGIGDPKYFPVTDVAHLNKLLVDVLDSYNEVNAVMNLVLFDDAVAHICKINRILESPRGNALLVGVGGSGKQSLSRLAAYISALDVFQITLKKGYSIPDLKIDLAAQYIKSAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFGEDDLENIIFSMRPQVKSLGMNDTREACWKFFIEKVRKQLKVGFHLDSCLGAQLSSSYPQPYMVRLGAPGGLGCVAWGPKMSGPAHLIHPGLQPEVKTSISLFMAYVHTTVNEMSKLYLAIERRYNYTTPKTFLEQIKLYQNLLAKKRMELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNENADKLIQVVGVETEKVSKEKAIADEEEIKVEVINKNVTEKQKACETDLAKAEPALIAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDALKKFDKEHIPEACLKAFRPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQDKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVISLANRLVGGLASENVRWAESVENFKNQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYINKLKVPIPITEGLDPLTLLTDDADVASWNNQGLPSDRMSTENATILCNTERWPLIVDAQLQGIKWIKNKYGDELKAIRLGQKSYLDIIEHAISDGDILLIENIGETVDPVLDPLLGRNTIKKGKFIKIGDKEVEYHPNFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKASLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTANEIEEKVQEAKITESKINEARENYRPAAARASLLYFILNDLNKINPIYQFSLKAFNVVFEKAIQNTMPAEEVKQRVMNLTDEITYSVFMYTARGLFERDKLIFLAQVTFQVLSMKKELNPMELDFLLRFPFKAGVVSPVDFLQHQSWGGIKALAEMDEFKNLDNDIEGSAKRWKKLVESEAPEKEVFPKEWKNKTALQKLCMVRCMRPDRMTYAVKNFVEEKMGSKFVEGRSLEFSKSYKESSPSTPIFFILSPGVDPLKDVEALGKRLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQNIHLVARWLSTLDKKVERFSSGSHEDYRVFISAEPAPTPEAHIIPQGILENAIKITNEPPTGMYANLHKALDLFTQDTLEMCTKEIEFKCILFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLMEFIRVEMLEGEVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDEILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDMEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLQRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKDLTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV", "length": 4454, "header": "tr|A0A9J7H5N7-1|A0A9J7H5N7_CRIGR Isoform 1 of LOW QUALITY PROTEIN: dynein heavy chain 17, axonemal isoform X3 OS=Cricetulus griseus OX=10029 GN=Dnah17 PE=3 SV=1 CANONICAL=A0A9J7H5N7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H5N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N7/entry#A0A9J7H5N7-1", "sequence": { "sequence": "MPDARLDYLENVSFIVLKYKADKWGKLIGAEENMAMLTEFFDKADIPVLVLTLNPAGMIVPCLGFPETLKSKGLYFIKTKPENVTKDNYKTRLLFGDISPTPVEQLIAVVEEVLYSLLNQSENMNGWPRVVSEDIVKQVHRLKNEMFVMGGKVKGKTLLPIPEHLGSLDGTLESMERIPSTLDNSLLHSIETIIIDWSHQIRDVLSKDSAQALLDGLHPLPRVEFDFWDARLMNLRCIHEQLNRPKVNKIVEILEKAKSCYWPALQNVYMNVTQGLKEASDIVLYLKPLRILLDEMEQADFTVLPNFIVKVLSTICFIWATSEHYNTPSRVIVILREFSNQIIEMTRTYLSPEEVLKGLQGEIEEVLFGISLSVGVLKELFHAYDFCCANMKIFFKDKTPVPWEFPSSLAFSRMNSFFHRVQTIEDLYKTAIEFLKLEKIEVGGVRGNILGNLVTQIYDEVFDLVKVFAECKYDPLDPGDSSFDDDYKDFETKIQDLDRRLATIFCQAFDDCSSIESAAKLLYMCGGLLERPLILVEVVPRYSVLLEMFNNELDNAKLMYDAQMAASAQGQIPPIHKNMSSVAGQLKWSLELQERLEVSMRHLKHIEHPVMSSVEAKLVYEKYDEMMELLKGSREKIYQQWVAGVDQDCHFNLGQPLIQRDPYSNLIQVNFSKALVAVLREVKYLTFQHQKEIPTSAETLFSENETFRKFVGNLELIVGWYNEIKTTVMEVEFPLIKLELEEIDIKLLSAETTLFWNGENVFQYIQEMREVLYNLQNRIQKAKQNVEGITQAMQEWSANPLFERKDNKKEALLDLDGRVANLNKRYAAVKDAGVRIQAMVAENAELFRADTTSQPWKDYVNYIDSMVLDEFDHFIRKSLTYLMDNMTMDESIAPLFEIRMELDEEGLTYNPSLEMGEEGGFLMLIEGLINDLYNVARLIPRLAKGRINYKTDLEDITDLIEMREEVSNLVIGAMKVAEEYQDSFERYSYLWVDDLQESMKNFLIFGHTPTPEELDTRVDDTIPKTPPSLAQFQQQIDSYEKLYEEVSRCENTKVFHGWLQCDCRPFKQALLNTIKRWSFLFKRYLSNHVTNSLDDLENFMTVTRSGLKKPLKEGDYDGLVEVMGHLMKVKERQVATDSMFEPLKQTIELLKSYGEEMPEETHLKLQELPEKWTHTKKLAIQVKQNVSPLQANEVNILRRKCQQFELKQHEFREKFRREAPFSFSDPEPYKSLNKQQKSISAMESVMEALCKSAGLFEVTVPDYKQLKACHKEVRLLKELWDMIVMVNTSIDDWKTTKWKDINVEQMDIDCKKFAKDVRSLDKEMKTWDAFVGLDNTVKNMITSLRAVSELQNPAIRDRHWQQLMQATQVKFEMSEETTLADLLQLNLHKYEDEVRNIVDKAVKESGMEKILKALDSTWTTMEFEHEPHPRTGTMMLKSDEVLVETLEDNQVQLQNLMMSKYLSHFLKEVTSWQQKLSTADSVISIWFEVQRTWGHLESIFIGSEDIRAQLPEDSKRFDGIDQEFKALMADAVKTPNVVEATNKPGLYDKLEMLKKSLAVCEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASGQPVKIGLGMYSKEDEFVDFDRECDLSGQVEVWLNRVLDRMCATLRHEIPEAVVTYEEKPREQWIFDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIKDYNKKQISQLNALITLLIGNLSPGDRMKIMTICTIDVHARDVVAKMITAKVESSQAFTWQSQLRHRWDEEKKHCFANICDAQIQYSYEYLGNTPRLVITPLTDRXGPDTHPSAPHTSLGQVSGPPEGTDRNLLPAGLWKSLPPSDTSLSFSSXSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKKFNFLGEIISLIPTVGIFITMNPGYAGRTELPENLKALFRPCAMVVPDFELICEIMLVAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPTRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIIELKLQAEDSFVLKVVQLEELLQVRHSVFVIGNAGSGKSQVLKSLNKTYQNMKRKPVAVDLDPKAVTCDELFGIINPATREWKDGLFSTIMRDLANITHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLTILFDKYLPTCLDKLRVGFKRITPVPEITIIQTILYLLECLLTEKNAPPDSPKELYELYFVFACFWAFGGAMFQDQLIDYRVEFSRWWINEFKTIKLPSQGTIFDYYIDPETKKFMPWTDKVPAFELDPDVPLQASLVHTTETIRIRYFMDLLMAKAWPVMLVGNAGTGKSVLMGDKLESLGTDDYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLIYFIDDMNMPEVDKYGTVAPHTLIRQHMDHGHWYDRQKLTLKDVHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALITIYNTILAQHLSYRSTPLVIQRLSNQLVNAALALHQKIASTFLPTAIKFHYIFNLRDLSNIFQGILFSLAEILRTPLDLVRLWLHEAERVYGDKMVDDKDQETLRRVTMASTKKFFDDLGEEHIFARPNIFCHFAQGIGDPKYFPVTDVAHLNKLLVDVLDSYNEVNAVMNLVLFDDAVAHICKINRILESPRGNALLVGVGGSGKQSLSRLAAYISALDVFQITLKKGYSIPDLKIDLAAQYIKSAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFGEDDLENIIFSMRPQVKSLGMNDTREACWKFFIEKVRKQLKVGFHLDSCLGAQLSSSYPQPYMVRLGAPGGLGCVAWGPKMSGPAHLIHPGLQPEVKTSISLFMAYVHTTVNEMSKLYLAIERRYNYTTPKTFLEQIKLYQNLLAKKRMELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNENADKLIQVVGVETEKVSKEKAIADEEEIKVEVINKNVTEKQKACETDLAKAEPALIAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDALKKFDKEHIPEACLKAFRPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQDKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVISLANRLVGGLASENVRWAESVENFKNQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYINKLKVPIPITEGLDPLTLLTDDADVASWNNQGLPSDRMSTENATILCNTERWPLIVDAQLQGIKWIKNKYGDELKAIRLGQKSYLDIIEHAISDGDILLIENIGETVDPVLDPLLGRNTIKKGKFIKIGDKEVEYHPNFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKASLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTANEIEEKVQEAKITESKINEARENYRPAAARASLLYFILNDLNKINPIYQFSLKAFNVVFEKAIQNTMPAEEVKQRVMNLTDEITYSVFMYTARGLFERDKLIFLAQVTFQVLSMKKELNPMELDFLLRFPFKAGVVSPVDFLQHQSWGGIKALAEMDEFKNLDNDIEGSAKRWKKLVESEAPEKEVFPKEWKNKTALQKLCMVRCMRPDRMTYAVKNFVEEKMGSKFVEGRSLEFSKSYKESSPSTPIFFILSPGVDPLKDVEALGKRLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQNIHLVARWLSTLDKKVERFSSGSHEDYRVFISAEPAPTPEAHIIPQGILENAIKITNEPPTGMYANLHKALDLFTQDTLEMCTKEIEFKCILFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLMEFIRVEMLEGEVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDEILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDMEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLQRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKDLTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV", "length": 4454, "header": "tr|A0A9J7H5N7-1|A0A9J7H5N7_CRIGR Isoform 1 of LOW QUALITY PROTEIN: dynein heavy chain 17, axonemal isoform X3 OS=Cricetulus griseus OX=10029 GN=Dnah17 PE=3 SV=1 CANONICAL=A0A9J7H5N7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 101, "start_aa": "Thr", "end_pos": 101, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr101", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3965, "start_aa": "Thr", "end_pos": 3965, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3965", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768695", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768695", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N7" } ], "pmid": "" }, { "name": "minus-end-directed microtubule motor activity", "id": "GO:0008569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008569", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N7" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N7" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N7" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N7" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N7" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5N7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5N7" } ], "pmid": "" } ] } ] }, "pro_annotation": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027286824", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286824", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GKD8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GKD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GKD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GKD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7T1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7T1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7T1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTCEAEQRAPDGEERGDSSKGPRRVPVFVPKTETQRKATVTMAASSVTAPQGLLTFRNVSVDFSQEEWECLDSSQRALYMDVMWENYSNLVFVENHCICGKNEIVLNQGSKHIVHEDVKTQEKSHSCHELGVTIHESSQCIPYNTSGTTENCQGYRSGNHRDASTDSSNLRRHGSGNTGEEQYKYKDYGECLNMCSTISQSPQIHAGKEEHKNAEYDELFDSKRELTMKLIRNGKKRPQCRKCGKCFRTHLSLSRHQRAHPAEKPCKFIECDKSSLLLSHRKVQKTHYRGKPSKCTECGKCFYHSSGFKSCRIHTGEESYKCKNCRKSFICCSGLRKLRVSQRPYKCKQCSKSFYTLSHLEYHYRRHSGEKLYKCNECGKSLSTSSSLKKHQRIHTGEKIYRCSECGKSFTFRTSLRLHQRIHTGEKPYKCNECGKCFIQKVNLRTHQTIHSGEKPYKCSECGKSFTVGSGLRRHQTVHTGEKPYKCGKCGKSFPIVSDLRNHQKIHTGEKPHKCSECEKCFIWKADLRTHQKVHTGEKPYRCSECGKSFTTGSGLRRHERIHTGERPYKCTECDKYFVQKTNLRRHQRIHTGEKPYHCSECGKSFNTDSYLRIHQKIHTGERPYKCGECDKYFIQKAKLRIHQKIHTGEKPFNCSECDKCFIQKGNLISHQRIHTGEKPYKCSGCDKSFTIGSVLRKHEKTHTGRNTLILYPGSQV", "length": 718, "header": "tr|A0A9J7H7T1-1|A0A9J7H7T1_CRIGR Isoform 1 of Zinc finger protein 345-like isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC113837322 PE=3 SV=1 CANONICAL=A0A9J7H7T1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GKD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7T1/entry#A0A9J7GKD8-1", "sequence": { "sequence": "MAASSVTAPQGLLTFRNVSVDFSQEEWECLDSSQRALYMDVMWENYSNLVFVENHCICGKNEIVLNQGSKHIVHEDVKTQEKSHSCHELGVTIHESSQCIPYNTSGTTENCQGYRSGNHRDASTDSSNLRRHGSGNTGEEQYKYKDYGECLNMCSTISQSPQIHAGKEEHKNAEYDELFDSKRELTMKLIRNGKKRPQCRKCGKCFRTHLSLSRHQRAHPAEKPCKFIECDKSSLLLSHRKVQKTHYRGKPSKCTECGKCFYHSSGFKSCRIHTGEESYKCKNCRKSFICCSGLRKLRVSQRPYKCKQCSKSFYTLSHLEYHYRRHSGEKLYKCNECGKSLSTSSSLKKHQRIHTGEKIYRCSECGKSFTFRTSLRLHQRIHTGEKPYKCNECGKCFIQKVNLRTHQTIHSGEKPYKCSECGKSFTVGSGLRRHQTVHTGEKPYKCGKCGKSFPIVSDLRNHQKIHTGEKPHKCSECEKCFIWKADLRTHQKVHTGEKPYRCSECGKSFTTGSGLRRHERIHTGERPYKCTECDKYFVQKTNLRRHQRIHTGEKPYHCSECGKSFNTDSYLRIHQKIHTGERPYKCGECDKYFIQKAKLRIHQKIHTGEKPFNCSECDKCFIQKGNLISHQRIHTGEKPYKCSGCDKSFTIGSVLRKHEKTHTGRNTLILYPGSQV", "length": 676, "header": "tr|A0A9J7GKD8-1|A0A9J7GKD8_CRIGR Computationally mapped isoform of Zinc finger protein 345-like isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC113837322 PE=3 SV=1 CANONICAL=A0A9J7H7T1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H5P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7T1/entry#A0A9J7H5P3-1", "sequence": { "sequence": "MLTCEAEQRAPDGEERGDSSKGPRVPVFVPKTETQRKATVTMAASSVTAPQGLLTFRNVSVDFSQEEWECLDSSQRALYMDVMWENYSNLVFVENHCICGKNEIVLNQGSKHIVHEDVKTQEKSHSCHELGVTIHESSQCIPYNTSGTTENCQGYRSGNHRDASTDSSNLRRHGSGNTGEEQYKYKDYGECLNMCSTISQSPQIHAGKEEHKNAEYDELFDSKRELTMKLIRNGKKRPQCRKCGKCFRTHLSLSRHQRAHPAEKPCKFIECDKSSLLLSHRKVQKTHYRGKPSKCTECGKCFYHSSGFKSCRIHTGEESYKCKNCRKSFICCSGLRKLRVSQRPYKCKQCSKSFYTLSHLEYHYRRHSGEKLYKCNECGKSLSTSSSLKKHQRIHTGEKIYRCSECGKSFTFRTSLRLHQRIHTGEKPYKCNECGKCFIQKVNLRTHQTIHSGEKPYKCSECGKSFTVGSGLRRHQTVHTGEKPYKCGKCGKSFPIVSDLRNHQKIHTGEKPHKCSECEKCFIWKADLRTHQKVHTGEKPYRCSECGKSFTTGSGLRRHERIHTGERPYKCTECDKYFVQKTNLRRHQRIHTGEKPYHCSECGKSFNTDSYLRIHQKIHTGERPYKCGECDKYFIQKAKLRIHQKIHTGEKPFNCSECDKCFIQKGNLISHQRIHTGEKPYKCSGCDKSFTIGSVLRKHEKTHTGRNTLILYPGSQV", "length": 717, "header": "tr|A0A9J7H5P3-1|A0A9J7H7T1_CRIGR Computationally mapped isoform of Zinc finger protein 345-like isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC113837322 PE=3 SV=1 CANONICAL=A0A9J7H7T1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7T1/entry#A0A9J7H7T1-1", "sequence": { "sequence": "MLTCEAEQRAPDGEERGDSSKGPRRVPVFVPKTETQRKATVTMAASSVTAPQGLLTFRNVSVDFSQEEWECLDSSQRALYMDVMWENYSNLVFVENHCICGKNEIVLNQGSKHIVHEDVKTQEKSHSCHELGVTIHESSQCIPYNTSGTTENCQGYRSGNHRDASTDSSNLRRHGSGNTGEEQYKYKDYGECLNMCSTISQSPQIHAGKEEHKNAEYDELFDSKRELTMKLIRNGKKRPQCRKCGKCFRTHLSLSRHQRAHPAEKPCKFIECDKSSLLLSHRKVQKTHYRGKPSKCTECGKCFYHSSGFKSCRIHTGEESYKCKNCRKSFICCSGLRKLRVSQRPYKCKQCSKSFYTLSHLEYHYRRHSGEKLYKCNECGKSLSTSSSLKKHQRIHTGEKIYRCSECGKSFTFRTSLRLHQRIHTGEKPYKCNECGKCFIQKVNLRTHQTIHSGEKPYKCSECGKSFTVGSGLRRHQTVHTGEKPYKCGKCGKSFPIVSDLRNHQKIHTGEKPHKCSECEKCFIWKADLRTHQKVHTGEKPYRCSECGKSFTTGSGLRRHERIHTGERPYKCTECDKYFVQKTNLRRHQRIHTGEKPYHCSECGKSFNTDSYLRIHQKIHTGERPYKCGECDKYFIQKAKLRIHQKIHTGEKPFNCSECDKCFIQKGNLISHQRIHTGEKPYKCSGCDKSFTIGSVLRKHEKTHTGRNTLILYPGSQV", "length": 718, "header": "tr|A0A9J7H7T1-1|A0A9J7H7T1_CRIGR Isoform 1 of Zinc finger protein 345-like isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC113837322 PE=3 SV=1 CANONICAL=A0A9J7H7T1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5P3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5P3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113837322", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837322", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7T1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7T1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7T1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7T1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7T1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7T1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7T1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7T1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7T1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7T1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7T1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7T1" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7T1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7T1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" }, { "start_pos": 655, "end_pos": 657, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H5S0-1", "uniprot_ac": "A0A9J7H5S0", "uniprot_id": "A0A9J7H5S0_CRIGR", "mass": { "chemical_mass": 19281.0, "monoisotopic_mass": 19281.0 }, "refseq": { "ac": "XP_035304390", "name": "von Hippel-Lindau disease tumor suppressor isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304390" }, "gene_names": [ { "name": "Vhl", "type": "recommended", "evidence": [ { "id": "A0A9J7H5S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5S0" } ] }, { "name": "Vhl", "type": "synonym", "evidence": [ { "id": "XP_035304390", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304390" } ] } ], "protein_names": [ { "name": "von Hippel-Lindau disease tumor suppressor", "type": "recommended", "evidence": [ { "id": "A0A9J7H5S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5S0/entry#names_and_taxonomy" } ] }, { "name": "pVHL", "type": "synonym", "evidence": [ { "id": "A0A9J7H5S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5S0/entry#names_and_taxonomy" } ] }, { "name": "von Hippel-Lindau disease tumor suppressor isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035304390", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304390" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304390" } ] }, { "annotation": "Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2. 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This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305381", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305381" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5T4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100766315", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5T4", "locus": {} } ], "crossref": [ { "id": "cd19941", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19941", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766315", "url": "https://www.ncbi.nlm.nih.gov/gene/100766315", "database": "GeneID", "categories": [ 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"glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H5U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5U9#function" }, { "id": "A0A9J7H5U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5U9" }, { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" } ], "binding_site_uniprot": 317, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 317, "end_pos": 317, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.16.4", "ec_name": "(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin.", "evidence": [ { "id": "1.14.16.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.16.4" }, { "id": "1.14.16.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.16.4" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H5V0-1", "uniprot_ac": "A0A9J7H5V0", "uniprot_id": "A0A9J7H5V0_CRIGR", "mass": { "chemical_mass": 93473.0, "monoisotopic_mass": 93473.0 }, "refseq": { "ac": "XP_035304443", "name": "probable ubiquitin carboxyl-terminal hydrolase MINDY-4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304443" }, "gene_names": [ { "name": "Mindy4", "type": "recommended", "evidence": [ { "id": "A0A9J7H5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0" } ] }, { "name": "Mindy4", "type": "synonym", "evidence": [ { "id": "XP_035304443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304443" } ] } ], "protein_names": [ { "name": "Ubiquitin carboxyl-terminal hydrolase MINDY", "type": "recommended", "evidence": [ { "id": "A0A9J7H5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "A0A9J7H5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0/entry#names_and_taxonomy" } ] }, { "name": "probable ubiquitin carboxyl-terminal hydrolase MINDY-4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035304443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304443" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304443" } ] }, { "annotation": "Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K131", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K131#function" }, { "database": "UniProtKB", "id": "RU367088", "url": "https://www.uniprot.org/uniprotkb/RU367088#function" }, { "database": "UniProtKB", "id": "A0A9J7KAR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAR2#function" }, { "database": "UniProtKB", "id": "A0A9J7KC67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC67#function" }, { "database": "UniProtKB", "id": "A0A9J7H5V0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0#function" }, { "database": "UniProtKB", "id": "A0A9J7GIU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIU1#function" }, { "database": "UniProtKB", "id": "A0A9J7GIV5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIV5#function" } ] }, { "annotation": "Probable hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K131", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K131#function" }, { "database": "UniProtKB", "id": "ARBA00037630", "url": "https://www.uniprot.org/uniprotkb/ARBA00037630#function" }, { "database": "UniProtKB", "id": "A0A9J7KAR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAR2#function" }, { "database": "UniProtKB", "id": "A0A9J7KC67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC67#function" }, { "database": "UniProtKB", "id": "A0A9J7H5V0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0#function" }, { "database": "UniProtKB", "id": "A0A9J7GIU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIU1#function" }, { "database": "UniProtKB", "id": "A0A9J7GIV5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIV5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5V0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mindy4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0", "locus": {} } ], "crossref": [ { "id": "A0A9J7H5V0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H5V0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100773513", "url": "https://www.ncbi.nlm.nih.gov/gene/100773513", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025257", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025257", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059022", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059022", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773513", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773513", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H5V0", "url": "https://www.orthodb.org/?gene=A0A9J7H5V0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12473", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12473", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12473:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12473:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13898", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13898", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304443", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GIU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GIU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GIV5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GIV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5V0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K131", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K131", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K131-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K131-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KC67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KC67-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLPSSLPRPWNAGSPGRGGVLPGAEATVATATPLYWAQRIPRVLGLQAAAWPGGSTSSMDSLYVEEVAASLVREFLSRKGLKKTFVTMDQERPRCELSINSRNDLRKVLHLEFLYRENKAKEKPLKTNLELITRYFLDHSGNTDDLSQETLIPALPVPKTNNKLPSSCLETTLVNIYDLSDEDTGRRTSWSEAGKARHDNFDGDTLGNFISPKKSPYKSKPVHTVAGDSLPLVPAWEKVEQLHSSEPCIDVKRPVERTRPKSGLIVRGMMAGPVASSPQDSFRKRSLRRSSSLSRKLQAPEECQQPSESLVQTPACPGPQEVPSSSSDSVSRSPLGQLNELPMEKPNASPSSQGPSQRDRARLRRVSEDGLLGSSHTETSTTSLKLYLPGGNSRVTQERPERAFKRQGSQPPSLRKNQLVSDKASDKPDALWLATPWLCFLPEDVEDELIKEDIVLSPLPSMPKLQAVSKPIDLSLAKEMKTLLFGSTFCCFSEEWKLQNFSFSDTASLKYGIVQNKGGPCGVLAAVQGCVLKKLLFDEGSRTNSNLRGRFQHSLNSHISVRRSDIFCRLKPSDAQRTHCLALAIADILWRAGGKEQAVVALASGTAHFSPTGKYKADGVLETLTLYSLTCSEDLVTFLQQRIHQFEVGPYGCILLTLSAILSRSLELVRQDFDVPTSHLIGAHGYCTQELVNLLLTGRAVSNVFNDVVELDSGDGNTMLLRGIKARSDIGFLSLFEHYNVCQVGCFLKTPRFPIWVVCSESHFSILFSLQPELLSDWRTERLFDLYYYDGLANQQEEIRLTVDTTKTSPEDSCRDLVPPLELCIRTKWKGASVNWNGSDPIL", "length": 844, "header": "tr|A0A9J7H5V0-1|A0A9J7H5V0_CRIGR Isoform 1 of Ubiquitin carboxyl-terminal hydrolase MINDY OS=Cricetulus griseus OX=10029 GN=Mindy4 PE=3 SV=1 CANONICAL=A0A9J7H5V0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GIU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0/entry#A0A9J7GIU1-1", "sequence": { "sequence": "MDSLYVEEVAASLVREFLSRKGLKKTFVTMDQERPRCELSINSRNDLRKVLHLEFLYRENKAKEKPLKTNLELITRYFLDHSGNTDDLSQETLIPALPVPKTNNKLPSSCLETTLVNIYDLSDEDTGRRTSWSEAGKARHDNFDGDTLGNFISPKKSPYKSKPVHTVAGDSLPLVPAWEKVEQLHSSEPCIDVKRPVERTRPKSGLIVRGMMAGPVASSPQDSFRKRSLRRSSSLSRKLQAPEECQQPSESLVQTPACPGPQEVPSSSSDSVSRSPLGQLNELPMEKPNASPSSQGPSQRDRARLRRVSEDGLLGSSHTETSTTSLKLYLPGGNSRVTQERPERAFKRQGSQPPSLRKNQLVSDKASDKPDALWLEDVEDELIKEDIVLSPLPSMPKLQAVSKPIDLSLAKEMKTLLFGSTFCCFSEEWKLQNFSFSDTASLKYGIVQNKGGPCGVLAAVQGCVLKKLLFDEGSRTNSNLRLKPSDAQRTHCLALAIADILWRAGGKEQAVVALASGTAHFSPTGKYKADGVLETLTLYSLTCSEDLVTFLQQRIHQFEVGPYGCILLTLSAILSRSLELVRQDFDVPTSHLIGAHGYCTQELVNLLLTGRAVSNVFNDVVELDSGDGNTMLLRGIKARSDIGFLSLFEHYNVCQVGCFLKTPRFPIWVVCSESHFSILFSLQPELLSDWRTERLFDLYYYDGLANQQEEIRLTVDTTKTSPEDSCRDLVPPLELCIRTKWKGASVNWNGSDPIL", "length": 755, "header": "tr|A0A9J7GIU1-1|A0A9J7GIU1_CRIGR Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase MINDY OS=Cricetulus griseus OX=10029 GN=Mindy4 PE=3 SV=1 CANONICAL=A0A9J7H5V0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GIV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0/entry#A0A9J7GIV5-1", "sequence": { "sequence": "MLLPSSLPRPWNAGSPGRGGVLPGAEATVATATPLYWAQRIPRVLGLQAAAWPGGSTSSMDSLYVEEVAASLVREFLSRKGLKKTFVTMDQERPRCELSINSRNDLRKVLHLEFLYRENKAKEKPLKTNLELITRYFLDHSGNTDDLSQETLIPALPVPKTNNKLPSSCLETTLVNIYDLSDEDTGRRTSWSEAGKARHDNFDGDTLGNFISPKKSPYKSKPVHTVAGDSLPLVPAWEKVEQLHSSEPCIDVKRPVERTRPKSGLIVRGMMAGPVASSPQDSFRKRSLRRSSSLSRKLQAPEECQQPSESLVQTPACPGPQEVPSSSSDSVSRSPLGQLNELPMEKPNASPSSQGPSQRDRARLRRVSEDGLLGSSHTETSTTSLKLYLPGGNSRVTQERPERAFKRQGSQPPSLRKNQLVSDKASDKPDALWLEDVEDELIKEDIVLSPLPSMPKLQAVSKPIDLSLAKEMKTLLFGSTFCCFSEEWKLQNFSFSDTASLKYGIVQNKGGPCGVLAAVQGCVLKKLLFDEGSRTNSNLRGRFQHSLNSHISVRRSDIFCRLKPSDAQRTHCLALAIADILWRAGGKEQAVVALASGTAHFSPTGKYKADGVLETLTLYSLTCSEDLVTFLQQRIHQFEVGPYGCILLTLSAILSRSLELVRQDFDVPTSHLIGAHGYCTQELVNLLLTGRAVSNVFNDVVELDSGDGNTMLLRGIKARSDIGFLSLFEHYNVCQVGCFLKTPRFPIWVVCSESHFSILFSLQPELLSDWRTERLFDLYYYDGLANQQEEIRLTVDTTKTSPEDSCRDLVPPLELCIRTKWKGASVNWNGSDPIL", "length": 835, "header": "tr|A0A9J7GIV5-1|A0A9J7GIV5_CRIGR Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase MINDY OS=Cricetulus griseus OX=10029 GN=Mindy4 PE=3 SV=1 CANONICAL=A0A9J7H5V0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H5V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0/entry#A0A9J7H5V0-1", "sequence": { "sequence": "MLLPSSLPRPWNAGSPGRGGVLPGAEATVATATPLYWAQRIPRVLGLQAAAWPGGSTSSMDSLYVEEVAASLVREFLSRKGLKKTFVTMDQERPRCELSINSRNDLRKVLHLEFLYRENKAKEKPLKTNLELITRYFLDHSGNTDDLSQETLIPALPVPKTNNKLPSSCLETTLVNIYDLSDEDTGRRTSWSEAGKARHDNFDGDTLGNFISPKKSPYKSKPVHTVAGDSLPLVPAWEKVEQLHSSEPCIDVKRPVERTRPKSGLIVRGMMAGPVASSPQDSFRKRSLRRSSSLSRKLQAPEECQQPSESLVQTPACPGPQEVPSSSSDSVSRSPLGQLNELPMEKPNASPSSQGPSQRDRARLRRVSEDGLLGSSHTETSTTSLKLYLPGGNSRVTQERPERAFKRQGSQPPSLRKNQLVSDKASDKPDALWLATPWLCFLPEDVEDELIKEDIVLSPLPSMPKLQAVSKPIDLSLAKEMKTLLFGSTFCCFSEEWKLQNFSFSDTASLKYGIVQNKGGPCGVLAAVQGCVLKKLLFDEGSRTNSNLRGRFQHSLNSHISVRRSDIFCRLKPSDAQRTHCLALAIADILWRAGGKEQAVVALASGTAHFSPTGKYKADGVLETLTLYSLTCSEDLVTFLQQRIHQFEVGPYGCILLTLSAILSRSLELVRQDFDVPTSHLIGAHGYCTQELVNLLLTGRAVSNVFNDVVELDSGDGNTMLLRGIKARSDIGFLSLFEHYNVCQVGCFLKTPRFPIWVVCSESHFSILFSLQPELLSDWRTERLFDLYYYDGLANQQEEIRLTVDTTKTSPEDSCRDLVPPLELCIRTKWKGASVNWNGSDPIL", "length": 844, "header": "tr|A0A9J7H5V0-1|A0A9J7H5V0_CRIGR Isoform 1 of Ubiquitin carboxyl-terminal hydrolase MINDY OS=Cricetulus griseus OX=10029 GN=Mindy4 PE=3 SV=1 CANONICAL=A0A9J7H5V0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K131-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0/entry#A0A9J7K131-1", "sequence": { "sequence": "MLLPSSLPRPWNAGSPGRGGVLPGAEATVATATPLYWAQRIPRVLGLQAAAWPGGSTSSMDSLYVEEVAASLVREFLSRKGLKKTFVTMDQERPRCELSINSRNDLRKVLHLEFLYRENKAKEKPLKTNLELITRYFLDHSGNTDDLSQETLIPALPVPKTNNKLPSSCLETTLVNIYDLSDEDTGRRTSWSEAGKARHDNFDGDTLGNFISPKKSPYKSKPVHTVAGDSLPLVPAWEKVEQLHSSEPCIDVKRPVERTRPKSGLIVRGMMAGPVASSPQDSFRKRSLRRSSSLSRKLQAPEECQQPSESLVQTPACPGPQEVPSSSSDSVSRSPLGQLNELPMEKPNASPSSQGPSQRDRARLRRVSEDGLLGSSHTETSTTSLKLYLPGGNSRVTQERPERAFKRQGSQPPSLRKNQLVSDKASDKPDALWLATPWLCFLPEDVEDELIKEDIVLSPLPSMPKLQAVSKPIDLSLAKEMKTLLFGSTFCCFSEEWKLQNFSFSDTASLKYGIVQNKGGPCGVLAAVQGCVLKKLLFDEGSRTNSNLRLKPSDAQRTHCLALAIADILWRAGGKEQAVVALASGTAHFSPTGKYKADGVLETLTLYSLTCSEDLVTFLQQRIHQFEVGPYGCILLTLSAILSRSLELVRQDFDVPTSHLIGAHGYCTQELVNLLLTGRAVSNVFNDVVELDSGDGNTMLLRGIKARSDIGFLSLFEHYNVCQVGCFLKTPRFPIWVVCSESHFSILFSLQPELLSDWRTERLFDLYYYDGLANQQEEIRLTVDTTKTSPEDSCRDLVPPLELCIRTKWKGASVNWNGSDPIL", "length": 823, "header": "tr|A0A9J7K131-1|A0A9J7H5V0_CRIGR Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase MINDY OS=Cricetulus griseus OX=10029 GN=Mindy4 PE=3 SV=1 CANONICAL=A0A9J7H5V0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0/entry#A0A9J7KAR2-1", "sequence": { "sequence": "MLLPSSLPRPWNAGSPGRGGVLPGAEATVATATPLYWAQRIPRVLGLQAAAWPGGSTSSMDSLYVEEVAASLVREFLSRKGLKKTFVTMDQERPRCELSINSRNDLRKVLHLEFLYRENKAKEKPLKTNLELITRYFLDHSGNTDDLSQETLIPALPVPKTNNKLPSSCLETTLVNIYDLSDEDTGRRTSWSEAGKARHDNFDGDTLGNFISPKKSPYKSKPVHTVAGDSLPLVPAWEKVEQLHSSEPCIDVKRPVERTRPKSGLIVRGMMAGPVASSPQDSFRKRSLRRSSSLSRKLQAPEECQQPSESLVQTPACPGPQEVPSSSSDSVSRSPLGQLNELPMEKPNASPSSQGPSQRDRARLRRVSEDGLLGSSHTETSTTSLKLYLPGGNSRVTQERPERAFKRQGSQPPSLRKNQLVSDKASDKPDALWLATPWLCFLPEDVEDELIKEDIVLSPLPSMPKLQAVSKPIDLSLAKEMKTLLFGSTFCCFSEEWKLQNFSFSDTASLKYGIVQNKGGPCGVLAAVQGCVLKKLLFDEGSRTNSNLVRQDFDVPTSHLIGAHGYCTQELVNLLLTGRAVSNVFNDVVELDSGDGNTMLLRGIKARSDIGFLSLFEHYNVCQVGCFLKTPRFPIWVVCSESHFSILFSLQPELLSDWRTERLFDLYYYDGLANQQEEIRLTVDTTKTSPEDSCRDLVPPLELCIRTKWKGASVNWNGSDPIL", "length": 723, "header": "tr|A0A9J7KAR2-1|A0A9J7H5V0_CRIGR Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase MINDY OS=Cricetulus griseus OX=10029 GN=Mindy4 PE=3 SV=1 CANONICAL=A0A9J7H5V0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KC67-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0/entry#A0A9J7KC67-1", "sequence": { "sequence": "MAPWLQQVSQSAQGCPGLKKTFVTMDQERPRCELSINSRNDLRKVLHLEFLYRENKAKEKPLKTNLELITRYFLDHSGNTDDLSQETLIPALPVPKTNNKLPSSCLETTLVNIYDLSDEDTGRRTSWSEAGKARHDNFDGDTLGNFISPKKSPYKSKPVHTVAGDSLPLVPAWEKVEQLHSSEPCIDVKRPVERTRPKSGLIVRGMMAGPVASSPQDSFRKRSLRRSSSLSRKLQAPEECQQPSESLVQTPACPGPQEVPSSSSDSVSRSPLGQLNELPMEKPNASPSSQGPSQRDRARLRRVSEDGLLGSSHTETSTTSLKLYLPGGNSRVTQERPERAFKRQGSQPPSLRKNQLVSDKASDKPDALWLATPWLCFLPEDVEDELIKEDIVLSPLPSMPKLQAVSKPIDLSLAKEMKTLLFGSTFCCFSEEWKLQNFSFSDTASLKYGIVQNKGGPCGVLAAVQGCVLKKLLFDEGSRTNSNLRGRFQHSLNSHISVRRSDIFCRLKPSDAQRTHCLALAIADILWRAGGKEQAVVALASGTAHFSPTGKYKADGVLETLTLYSLTCSEDLVTFLQQRIHQFEVGPYGCILLTLSAILSRSLELVRQDFDVPTSHLIGAHGYCTQELVNLLLTGRAVSNVFNDVVELDSGDGNTMLLRGIKARSDIGFLSLFEHYNVCQVGCFLKTPRFPIWVVCSESHFSILFSLQPELLSDWRTERLFDLYYYDGLANQQEEIRLTVDTTKTSPEDSCRDLVPPLELCIRTKWKGASVNWNGSDPIL", "length": 780, "header": "tr|A0A9J7KC67-1|A0A9J7H5V0_CRIGR Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase MINDY OS=Cricetulus griseus OX=10029 GN=Mindy4 PE=3 SV=1 CANONICAL=A0A9J7H5V0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K131", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K131" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K131", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K131" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773513", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773513", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5V0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0" } ], "pmid": "" }, { "name": "protein K48-linked deubiquitination", "id": "GO:0071108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071108", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5V0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5V0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0" } ], "pmid": "" }, { "name": "K48-linked deubiquitinase activity", "id": "GO:1990380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990380", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5V0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 838, "end_pos": 840, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V0" }, { "id": "SM01174", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01174" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Deubiquitinating enzyme MINDY-3/4 conserved", "eco_id": "ECO_0000259", "start_pos": 482, "end_pos": 839, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 348, "end_pos": 350 }, { "start_pos": 501, "end_pos": 503 }, { "start_pos": 838, "end_pos": 840 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H5V7-1", "uniprot_ac": "A0A9J7H5V7", "uniprot_id": "A0A9J7H5V7_CRIGR", "mass": { "chemical_mass": 59589.0, "monoisotopic_mass": 59589.0 }, "refseq": { "ac": "XP_035305437", "name": "CAP-Gly domain-containing linker protein 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305437" }, "gene_names": [ { "name": "Clip3", "type": "recommended", "evidence": [ { "id": "A0A9J7H5V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V7" } ] }, { "name": "Clip3", "type": "synonym", "evidence": [ { "id": "XP_035305437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305437" } ] } ], "protein_names": [ { "name": "CAP-Gly domain-containing linker protein 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305437" }, { "id": "A0A9J7H5V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305437" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5V7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Clip3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V7", "locus": {} } ], "crossref": [ { "id": "A0A9J7H5V7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H5V7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100771592", "url": "https://www.ncbi.nlm.nih.gov/gene/100771592", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771592", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771592", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H5V7", "url": "https://www.orthodb.org/?gene=A0A9J7H5V7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18916", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18916", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18916:SF77", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18916:SF77", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01302", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01302", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305437", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H5V7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKTDPAPMAPPPRGEEEVEEEEEEPVPEAPSPTQERRQKPVVHPSAPAPLPKDYAFTFFDPNDPACQEILFDPKTSIPELFAIVRQWVPQVQHKIDVIGNEILRRGCHVNDRDGLTDMTLLHYACKAGAHGVGDPAAAVRLSQQLLALGADVTLRSRWTNMNALHYAAYFDVPDLVRVLLKGARPRVVNSTCSDFNHGSALHIAASNLCLGAAKCLLEHGANPALRNRKGQVPAEVVPDPMDMSLDKAEAALVAKELRTLLEEAVPLSCTLPKVTLPNYDNVPGNLMLSALGLRLGDRVLLDGQKTGTLRFCGTTEFASGQWVGVELDEPEGKNDGSVGGVRYFICPPKQGLFASVSKISKAVDAPPSSVTSTPRTPRMDFSRMTGKGRREHKGKKKSPSSPSLGSLQQREGAKADVGDQVLVAGQKQGIVRFYGKTDFAPGYWYGIELDQPTGKHDGSVFGVRYFTCAPRHGVFAPASRIQRIGGSTDPPGDSVGAKKVHQVTMTQPKRTFTTVRTPKDIASENSISRLLFCCWFPWMLRAEMQS", "length": 547, "header": "tr|A0A9J7H5V7-1|A0A9J7H5V7_CRIGR Isoform 1 of CAP-Gly domain-containing linker protein 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Clip3 PE=4 SV=1 CANONICAL=A0A9J7H5V7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H5V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V7/entry#A0A9J7H5V7-1", "sequence": { "sequence": "MTKTDPAPMAPPPRGEEEVEEEEEEPVPEAPSPTQERRQKPVVHPSAPAPLPKDYAFTFFDPNDPACQEILFDPKTSIPELFAIVRQWVPQVQHKIDVIGNEILRRGCHVNDRDGLTDMTLLHYACKAGAHGVGDPAAAVRLSQQLLALGADVTLRSRWTNMNALHYAAYFDVPDLVRVLLKGARPRVVNSTCSDFNHGSALHIAASNLCLGAAKCLLEHGANPALRNRKGQVPAEVVPDPMDMSLDKAEAALVAKELRTLLEEAVPLSCTLPKVTLPNYDNVPGNLMLSALGLRLGDRVLLDGQKTGTLRFCGTTEFASGQWVGVELDEPEGKNDGSVGGVRYFICPPKQGLFASVSKISKAVDAPPSSVTSTPRTPRMDFSRMTGKGRREHKGKKKSPSSPSLGSLQQREGAKADVGDQVLVAGQKQGIVRFYGKTDFAPGYWYGIELDQPTGKHDGSVFGVRYFTCAPRHGVFAPASRIQRIGGSTDPPGDSVGAKKVHQVTMTQPKRTFTTVRTPKDIASENSISRLLFCCWFPWMLRAEMQS", "length": 547, "header": "tr|A0A9J7H5V7-1|A0A9J7H5V7_CRIGR Isoform 1 of CAP-Gly domain-containing linker protein 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Clip3 PE=4 SV=1 CANONICAL=A0A9J7H5V7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5V7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771592", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771592", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5V7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V7" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5V7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V7" } ], "pmid": "" }, { "name": "microtubule plus-end", "id": "GO:0035371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035371", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5V7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule plus-end binding", "id": "GO:0051010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051010", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5V7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5V7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H5V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5V7" }, { "id": "PS50245", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50245" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CAP-Gly", "eco_id": "ECO_0000259", "start_pos": 314, "end_pos": 356, "start_aa": "Gly", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 34 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H5X4-1", "uniprot_ac": "A0A9J7H5X4", "uniprot_id": "A0A9J7H5X4_CRIGR", "mass": { "chemical_mass": 53231.0, "monoisotopic_mass": 53231.0 }, "refseq": { "ac": "XP_035293219", "name": "anomalous homeobox protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293219" }, "gene_names": [ { "name": "Anhx", "type": "recommended", "evidence": [ { "id": "A0A9J7H5X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5X4" } ] }, { "name": "Anhx", "type": "synonym", "evidence": [ { "id": "XP_035293219", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293219" } ] } ], "protein_names": [ { "name": "Anomalous homeobox protein", "type": "synonym", "evidence": [ { "id": "A0A9J7H5X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5X4/entry#names_and_taxonomy" } ] }, { "name": "anomalous homeobox protein", "type": "synonym", "evidence": [ { "id": "XP_035293219", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293219" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 46% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615938.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035293219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293219" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5X4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5X4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Anhx", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5X4", "locus": {} } ], "crossref": [ { "id": "A0A9J7H5X4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H5X4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "118237889", "url": "https://www.ncbi.nlm.nih.gov/gene/118237889", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:118237889", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118237889", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H5X4", "url": "https://www.orthodb.org/?gene=A0A9J7H5X4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10390:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10390:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16878", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16878", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035293219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293219", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H5X4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5X4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5X4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQNFLRLLREQGDAQPLPPDLVILAGKLCQDFQQNPAQMIHLVETILESQHCWELLSNEEVALVCTQVLIQKEQWLLALQILKGCQVPGGSQELVELWNDIHYHLTTRRLSVTKLNPGQRFRCRKRNPPPPNICPEGPKSRNFLPEVRYHLQDFATSVGAYPKKAHLEKLALETGLTTEQVYNWFANYRRRQRALLLHMPRAQEASSEVSSAKESGPQPLQLSGYHHKSVAVSPGSVRGEGSWTLQSSEISPRSQGPQYPASSFSGDYKTSQPLAFRSLYGYESYQEWPGHHSAGLTSMGLTPGLCPLASVSPMVDSSVAAPESWMMPLMLPSFKEIFLPMEQLGCRQQLDSGMDPAVAPMAMAMAALRGPRHAGFTGLPGSRPQSLYPEEGPGPRSGQGASTPDCKLHHLQSSLEVMSASSAMQLPVSTREQSQPLPSSQVQWPGGQASWNAVWRATMLLEFSEGNIGQHARVGMGGQHME", "length": 482, "header": "tr|A0A9J7H5X4-1|A0A9J7H5X4_CRIGR Isoform 1 of Anomalous homeobox protein OS=Cricetulus griseus OX=10029 GN=Anhx PE=3 SV=1 CANONICAL=A0A9J7H5X4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H5X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5X4/entry#A0A9J7H5X4-1", "sequence": { "sequence": "MQNFLRLLREQGDAQPLPPDLVILAGKLCQDFQQNPAQMIHLVETILESQHCWELLSNEEVALVCTQVLIQKEQWLLALQILKGCQVPGGSQELVELWNDIHYHLTTRRLSVTKLNPGQRFRCRKRNPPPPNICPEGPKSRNFLPEVRYHLQDFATSVGAYPKKAHLEKLALETGLTTEQVYNWFANYRRRQRALLLHMPRAQEASSEVSSAKESGPQPLQLSGYHHKSVAVSPGSVRGEGSWTLQSSEISPRSQGPQYPASSFSGDYKTSQPLAFRSLYGYESYQEWPGHHSAGLTSMGLTPGLCPLASVSPMVDSSVAAPESWMMPLMLPSFKEIFLPMEQLGCRQQLDSGMDPAVAPMAMAMAALRGPRHAGFTGLPGSRPQSLYPEEGPGPRSGQGASTPDCKLHHLQSSLEVMSASSAMQLPVSTREQSQPLPSSQVQWPGGQASWNAVWRATMLLEFSEGNIGQHARVGMGGQHME", "length": 482, "header": "tr|A0A9J7H5X4-1|A0A9J7H5X4_CRIGR Isoform 1 of Anomalous homeobox protein OS=Cricetulus griseus OX=10029 GN=Anhx PE=3 SV=1 CANONICAL=A0A9J7H5X4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7H5X4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "skeletal muscle fiber development", "id": "GO:0048741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048741", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5X4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5X4" } ], "pmid": "" }, { "name": "regulation of skeletal muscle cell proliferation", "id": "GO:0014857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014857", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5X4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5X4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5X4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5X4" 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H5Y5-1", "uniprot_ac": "A0A9J7H5Y5", "uniprot_id": "A0A9J7H5Y5_CRIGR", "mass": { "chemical_mass": 84783.0, "monoisotopic_mass": 84783.0 }, "refseq": { "ac": "XP_035305655", "name": "synaptotagmin-like protein 5 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305655" }, "gene_names": [ { "name": "Sytl5", "type": "recommended", "evidence": [ { "id": "A0A9J7H5Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5" } ] }, { "name": "Sytl5", "type": "synonym", "evidence": [ { "id": "XP_035305655", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305655" } ] } ], "protein_names": [ { "name": "Synaptotagmin-like protein 5", "type": "recommended", "evidence": [ { "id": "A0A9J7H5Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5/entry#names_and_taxonomy" } ] }, { "name": "synaptotagmin-like protein 5 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_035305655", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305655" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305655", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305655" } ] }, { "annotation": "May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5#function" }, { "database": "UniProtKB", "id": "ARBA00053749", "url": "https://www.uniprot.org/uniprotkb/ARBA00053749#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sytl5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5", "locus": {} } ], "crossref": [ { "id": "A0A9J7H5Y5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H5Y5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04020", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04020", 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"MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQETSRVCVHCQKNLGLIFDRGDPCQVCALRVCSECRVTGLGGSWKCTVCAKVAQLKIISGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPGSEDIQSQEQARQDVDKSDMSSIRQKASHEGPKRKGFLLSKFRSVTRGEIRTPKPESGRSYSLDLDSQNLQNFKSAPGSDRRSAASSDLIDQEAGRGTPKNSYSNGGIPVTQRSPAPSARSVTSISSRYELLSVPQMKYSLACSFFVVRRVLLWLPFLTKSHRRNTSVTGASLSSDRSRSELDLSESFPEDIEDTSSIRSRSVPGALDKDLNSLEETEDGDDDLVSSGFSANPHSLVTGLSTNFQAGSDRKRSYLNVPDADSDTTSLNSMMSAYSETGDYGNVKVTGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRSNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIAFDSWNFENPCDEWFVLQPKVELAPDIGLQYKGELTVVLRYIPPEENSIFPVGQPQGKKTFKKGKKQESAVISGGILEVFIKEAKNLTSVKSGGSDSFVKGYLLPDDNKATKHKTVVVKKSVNPQWNHTFIFSGLYPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKTVDWMDSRGEEQRLWQKMVDNPGTSIEGVLMLRSSMAKCRL", "length": 756, "header": "tr|A0A9J7H5Y5-1|A0A9J7H5Y5_CRIGR Isoform 1 of Synaptotagmin-like protein 5 OS=Cricetulus griseus OX=10029 GN=Sytl5 PE=4 SV=1 CANONICAL=A0A9J7H5Y5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H5Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5/entry#A0A9J7H5Y5-1", "sequence": { "sequence": "MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQETSRVCVHCQKNLGLIFDRGDPCQVCALRVCSECRVTGLGGSWKCTVCAKVAQLKIISGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPGSEDIQSQEQARQDVDKSDMSSIRQKASHEGPKRKGFLLSKFRSVTRGEIRTPKPESGRSYSLDLDSQNLQNFKSAPGSDRRSAASSDLIDQEAGRGTPKNSYSNGGIPVTQRSPAPSARSVTSISSRYELLSVPQMKYSLACSFFVVRRVLLWLPFLTKSHRRNTSVTGASLSSDRSRSELDLSESFPEDIEDTSSIRSRSVPGALDKDLNSLEETEDGDDDLVSSGFSANPHSLVTGLSTNFQAGSDRKRSYLNVPDADSDTTSLNSMMSAYSETGDYGNVKVTGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRSNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIAFDSWNFENPCDEWFVLQPKVELAPDIGLQYKGELTVVLRYIPPEENSIFPVGQPQGKKTFKKGKKQESAVISGGILEVFIKEAKNLTSVKSGGSDSFVKGYLLPDDNKATKHKTVVVKKSVNPQWNHTFIFSGLYPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKTVDWMDSRGEEQRLWQKMVDNPGTSIEGVLMLRSSMAKCRL", "length": 756, "header": "tr|A0A9J7H5Y5-1|A0A9J7H5Y5_CRIGR Isoform 1 of Synaptotagmin-like protein 5 OS=Cricetulus griseus OX=10029 GN=Sytl5 PE=4 SV=1 CANONICAL=A0A9J7H5Y5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761117", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761117", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5" } ], "pmid": "" }, { "name": "neurexin family protein binding", "id": "GO:0042043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042043", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5" } ], "pmid": "" }, { "name": "exocytic vesicle", "id": "GO:0070382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070382", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" }, { "start_pos": 666, "end_pos": 668, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H5Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 433, "end_pos": 554, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H5Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Y5" }, { "id": "PS50916", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50916" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RabBD", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 123, "start_aa": "Phe", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 313, "end_pos": 315 }, { "start_pos": 501, "end_pos": 503 }, { "start_pos": 625, "end_pos": 627 }, { "start_pos": 666, "end_pos": 668 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H5Z6-1", "uniprot_ac": "A0A9J7H5Z6", "uniprot_id": "A0A9J7H5Z6_CRIGR", "mass": { "chemical_mass": 38729.0, "monoisotopic_mass": 38729.0 }, "refseq": { "ac": "XP_035304936", "name": "receptor expression-enhancing protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304936" }, "gene_names": [ { "name": "Reep1", "type": "recommended", "evidence": [ { "id": "A0A9J7H5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z6" } ] }, { "name": "Reep1", "type": "synonym", "evidence": [ { "id": "XP_035304936", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304936" } ] } ], "protein_names": [ { "name": "Receptor expression-enhancing protein", "type": "recommended", "evidence": [ { "id": "A0A9J7H5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z6/entry#names_and_taxonomy" } ] }, { "name": "receptor expression-enhancing protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035304936", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304936" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 22% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304936", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304936" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Z6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Reep1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z6", "locus": {} } ], "crossref": [ { "id": "A0A9J7H5Z6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H5Z6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100767668", "url": "https://www.ncbi.nlm.nih.gov/gene/100767668", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767668", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767668", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H5Z6", "url": "https://www.orthodb.org/?gene=A0A9J7H5Z6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12300:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12300:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304936", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304936", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H5Z6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPIITTMPGITTMPGITTMPTVTTMPGITTMPTVTTMPGITTMPTVTTMPGITTMPGITTMPGITTMPTVTTMPGITTMLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLCWFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVHFGKRGLNVAATAAVMAASKGQGALSERLRSFSMQDLTTIRGDGAPAPSGSPPPGTGRSSGKHGQPKMSRSASESAGSSVCTCCPTCRTRKVVEGDVNEGGVKSWEPHQVQSPLAFSDEEEEDLLEFMYKYKAPRRTELPLEAPPRTLRYRFRKKSTSSSATETT", "length": 352, "header": "tr|A0A9J7H5Z6-1|A0A9J7H5Z6_CRIGR Isoform 1 of Receptor expression-enhancing protein OS=Cricetulus griseus OX=10029 GN=Reep1 PE=3 SV=1 CANONICAL=A0A9J7H5Z6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H5Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z6/entry#A0A9J7H5Z6-1", "sequence": { "sequence": "MPIITTMPGITTMPGITTMPTVTTMPGITTMPTVTTMPGITTMPTVTTMPGITTMPGITTMPGITTMPTVTTMPGITTMLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLCWFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVHFGKRGLNVAATAAVMAASKGQGALSERLRSFSMQDLTTIRGDGAPAPSGSPPPGTGRSSGKHGQPKMSRSASESAGSSVCTCCPTCRTRKVVEGDVNEGGVKSWEPHQVQSPLAFSDEEEEDLLEFMYKYKAPRRTELPLEAPPRTLRYRFRKKSTSSSATETT", "length": 352, "header": "tr|A0A9J7H5Z6-1|A0A9J7H5Z6_CRIGR Isoform 1 of Receptor expression-enhancing protein OS=Cricetulus griseus OX=10029 GN=Reep1 PE=3 SV=1 CANONICAL=A0A9J7H5Z6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H5Z6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Z6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H616", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H616" }, { "id": "PF03939", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03939" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein uL23 N-terminal", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 67, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 93, 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H631-1", "uniprot_ac": "A0A9J7H631", "uniprot_id": "A0A9J7H631_CRIGR", "mass": { "chemical_mass": 89439.0, "monoisotopic_mass": 89439.0 }, "refseq": { "ac": "XP_035305012", "name": "LOW QUALITY PROTEIN: zinc finger protein 345", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305012" }, "gene_names": [ { "name": "LOC107977594", "type": "recommended", "evidence": [ { "id": "A0A9J7H631", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H631" } ] }, { "name": "LOC107977594", "type": "synonym", "evidence": [ { "id": "XP_035305012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305012" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: zinc finger protein 345", "type": "synonym", "evidence": [ { "id": "XP_035305012", "database": "RefSeq", "url": 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This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305012", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305012" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H631", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H631#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H631", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H631" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC107977594", "url": 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"MAALKKELRRTWIRERVERESKPLRTQKKETPPIPWPSPLQALKVAYGRSPMPSPNGLGSEKPIWVPEWCVPHVDLDSAPHPGPVQDNPDIIRVVWALVRNQPILMPVRQSSCLFPAFFSTNITLGMAASNIQLEQSFDPFAKSKALPLMQQPAGTPPSIPDITPMVVEDHHTREEIMLYRIRRDFGITIAIVASIAISVTPAAIAGQFCYAIQEMIPKECTQDNCQRETSGCLGNNSPGDLHIRWFSVGRCKECEKFFTNGSDLQVHQRIHTGERPHNCKFCGMSFTRGSTLQVHQRIHTVDKPYKCSDCGKSFKHKSTLQVHQRIHSGEKPYKCKDCGKSFTNGSYLQVHQRIHTGEKPYKCSDCGKSFKHKSTLQVHQRMHTGERPHNCKFCAKSFTRGSTLQVHQRIHTGEKPYKCSLCGKFFIQRTHLQIHQRMHTGERPHNCKFCAKSFTRGSALQVHQRIHTGEKPYKCSDCGKSFKHKSTLQVHQRIHSGEKPYKCKDCGKSFTNGSDLQVHQRIHTGEKPYKCSLCGKFFIQRIHLQVHQRIHTGEKPYKCSDCGKSFKHKSTLQVHQRIHSGEKPYKCKDCGKSFTNGSDLQVHQRIHTGEKPYKCSLCGKFFIQRIHLQVHQRIHTGEKPYKCKVCGKSFTSGSYLQVHQRIHTGEKPYNCKLCGKSFTRGSHLQIHQKIHTGMXPYKCSDCENIFKHKSTLQGHQRIHNGEKPYNFNECGKYFTNASDLQVHQRLHSREKPYNCKECGKFFNYGSDIQAHQRIHTGQKC", "length": 781, "header": "tr|A0A9J7H631-1|A0A9J7H631_CRIGR Isoform 1 of LOW QUALITY PROTEIN: zinc finger protein 345 OS=Cricetulus griseus OX=10029 GN=LOC107977594 PE=3 SV=1 CANONICAL=A0A9J7H631-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H631-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H631/entry#A0A9J7H631-1", "sequence": { "sequence": "MAALKKELRRTWIRERVERESKPLRTQKKETPPIPWPSPLQALKVAYGRSPMPSPNGLGSEKPIWVPEWCVPHVDLDSAPHPGPVQDNPDIIRVVWALVRNQPILMPVRQSSCLFPAFFSTNITLGMAASNIQLEQSFDPFAKSKALPLMQQPAGTPPSIPDITPMVVEDHHTREEIMLYRIRRDFGITIAIVASIAISVTPAAIAGQFCYAIQEMIPKECTQDNCQRETSGCLGNNSPGDLHIRWFSVGRCKECEKFFTNGSDLQVHQRIHTGERPHNCKFCGMSFTRGSTLQVHQRIHTVDKPYKCSDCGKSFKHKSTLQVHQRIHSGEKPYKCKDCGKSFTNGSYLQVHQRIHTGEKPYKCSDCGKSFKHKSTLQVHQRMHTGERPHNCKFCAKSFTRGSTLQVHQRIHTGEKPYKCSLCGKFFIQRTHLQIHQRMHTGERPHNCKFCAKSFTRGSALQVHQRIHTGEKPYKCSDCGKSFKHKSTLQVHQRIHSGEKPYKCKDCGKSFTNGSDLQVHQRIHTGEKPYKCSLCGKFFIQRIHLQVHQRIHTGEKPYKCSDCGKSFKHKSTLQVHQRIHSGEKPYKCKDCGKSFTNGSDLQVHQRIHTGEKPYKCSLCGKFFIQRIHLQVHQRIHTGEKPYKCKVCGKSFTSGSYLQVHQRIHTGEKPYNCKLCGKSFTRGSHLQIHQKIHTGMXPYKCSDCENIFKHKSTLQGHQRIHNGEKPYNFNECGKYFTNASDLQVHQRLHSREKPYNCKECGKFFNYGSDIQAHQRIHTGQKC", "length": 781, "header": "tr|A0A9J7H631-1|A0A9J7H631_CRIGR Isoform 1 of LOW QUALITY PROTEIN: zinc finger protein 345 OS=Cricetulus griseus OX=10029 GN=LOC107977594 PE=3 SV=1 CANONICAL=A0A9J7H631-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 201, "start_aa": "Thr", "end_pos": 201, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr201", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H631", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H631" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H631", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H631" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:107977594", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:107977594", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H631", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H631" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H631", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H631" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H631", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H631" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H631", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H631" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 597, "end_pos": 599, "annotation": "n_glycosylation_sequon" }, { "start_pos": 737, "end_pos": 739, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H631", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H631" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 250, "end_pos": 277, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 201 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 236, "end_pos": 238 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 513, "end_pos": 515 }, { "start_pos": 597, "end_pos": 599 }, { "start_pos": 737, "end_pos": 739 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H884-1", "uniprot_ac": "A0A9J7H884", "uniprot_id": "A0A9J7H884_CRIGR", "mass": { "chemical_mass": 209232.0, "monoisotopic_mass": 209232.0 }, "refseq": { "ac": "XP_035305544", "name": "fer-1-like protein 6 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305544" }, "gene_names": [ { "name": "LOC107977007", "type": "recommended", "evidence": [ { "id": "A0A9J7H884", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H884" } ] }, { "name": "LOC107977007", "type": "synonym", "evidence": [ { "id": "XP_035305544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305544" } ] } ], "protein_names": [ { "name": "Fer-1-like protein 6", "type": "recommended", "evidence": [ { "id": "A0A9J7H884", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H884/entry#names_and_taxonomy" } ] }, { "name": "fer-1-like protein 6 isoform X2", "type": 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This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305544", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305544" } ] }, { "annotation": "Calcium/phospholipid-binding protein which is essential for proper development of skeletal and cardiac muscle.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H884", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H884#function" }, { "database": "UniProtKB", "id": "ARBA00094315", "url": "https://www.uniprot.org/uniprotkb/ARBA00094315#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H884", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H884" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC107977007", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H884", "locus": {} } ], "crossref": [ { "id": "cd04011", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04011", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04017", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04017", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04018", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04018", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08374", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08374", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107977007", "url": "https://www.ncbi.nlm.nih.gov/gene/107977007", "database": "GeneID", 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"MFGLKLKKKKKNKAEKGLILTNKGAQDGQSDSEAPQEGPSHQERPEGDAVQDDTSITPGLSAPLKRRAKLLTKIHDGEVKSQSFQIAITITEARQLVGENIDPVVTIEIGEEKKQSTVKEGTNSPFYNEYFVFDFIGPQVHLFDKIIKISVLHHKLIGSILIGSFRVDVGTVYNQPGHQFCDKWALLTDPGDIRTGTKGYLKCDISVTGKGDVLQTNPKTFDAEEQVEKNLLIPQGFPSERPWARFYVRLYRAEGLPKMNSSIMANVTKAFVGDSKDLVDPFVEVSFAGQTGRTSVQKNCADPVWHEQVVFKEMFPPLCRRVKIQVWDEGSMSDVALATHFIDLKKISNEQDGDKGFLPTFGPAWINLYGSPRNQSLMDDYQELNEGFGEGVSFRGRILVEIAVEILSGGAQESKFSKALKELKLPSKDKDSKSSKGSSKDKADKTDDGKAQQAADKTNSTEVEVESFAVPPEIIPEKYEEFLLFGAFFEATMIDRKIGDKPISFEVSIGNFGNLIDGGSHHGSKKKSAELVEEDVLPLLHEGGKDVSHDSVISTSSTTHPEKPLVTEGNRNYSYLPFGAKKPCVSFISSWGDQTFRLHWSNMLGKMADLLEEGIEEVRELVKVSEEAPEEKMKTVLRAFISQSSAFISEAEKKPKMLNQTALDKKRLTLCWQELEAMVKEAKGVIQQQKKKLSVDEMIGEAQGYVEKIRFLVDEPQHTIPDVFIWMLSNNKRVAYARIAAKDLLYSPIPEQVGKYCGKIKTHFLKLPGKRPAGWTVQAKVDIYLWLGSTRYSNAILDNLPAGYEAETPSKASGTHHPPSTLLYQAQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSQCQTTKVISQTLSPTWNQMLLFNELVLHGEERELAESPPLVVVELYDSDAVGKPEYLGATVAAPVVTLANQDYEPPKLCYHPVFCGNLPGGDLLAVFELLQVPSSGLQGLPPIDPPDITQIYPVPSNIRPVLSKYRVEVLFWGVREMKKVQLLSVDRPQVLIECGGRGVKSCVIQSYKNNPNFSVQAEAFDVELPENELLHPPLSICVVDWRAFGRSTLVGTYTINCLKQFLCKSRETLALPSQRDGAWARPDSQGDIEPSRPSSSQDPPADHIYVDVDPPPTVVPDSAQAQTATLADIPDSSPMLEPEHKAVSQEPPKDGKVKQDPRKPSRRSTKRRKRTIADESAENVIDWWSKYDASLKKAQKEKENNTKEKRAMEAKPDEVVLDIDDGPKRKKDKMFKKKLKDEGSDGIPNLAVLKIYDGDLESEFNNFEDWVKTFELFRGKSSEDDHSLDGDRVIGKFKGSFCIYKSPEESTSEDSGQLRIQQGIPPNQPIQVLIRVYIVAAFNLSPADPDGKSDPYIVLRLGKTEIKDRDKYIPKQLNPVFGRSFEIQATLPKESLLSILIYDHDMIGSDDLIGETKIDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPHFHPGKIQIGNQVFSGKTVFTEEDSEEMVESYEHLALKVLHSWEDIPEVGCRLVPEHIESRPLYHKDKPGMEQGRLQMWVDMFPKDTPQLGPPVDISPRKPKGYELRVTIWNTEDVILEDENIFTGQKSSDIYVKGWIKGLEDDRQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQMVITKRENIFSLEKMECKSPAVLVLQVWDFERLSSDDFLGSLEMNLNSFPRAAKSAKACDLSKFENASEENKISIFQQKRVRGWWPFAKSKELTGKVEAEFHLVTAEEAEKNPVGKARKEPEPLAKPNRPDTSFSWFVSPFKCLYHLIWKNYKKYIIIAFILLILVVFLVLFIYTLPGAISRRIVVGGS", "length": 1861, "header": "tr|A0A9J7H884-1|A0A9J7H884_CRIGR Isoform 1 of Fer-1-like protein 6 OS=Cricetulus griseus OX=10029 GN=LOC107977007 PE=3 SV=1 CANONICAL=A0A9J7H884-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H643-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H884/entry#A0A9J7H643-1", "sequence": { "sequence": "MGKFEQEEMDVEVLHHKLIGSILIGSFRVDVGTVYNQPGHQFCDKWALLTDPGDIRTGTKGYLKCDISVTGKGDVLQTNPKTFDAEEQVEKNLLIPQGFPSERPWARFYVRLYRAEGLPKMNSSIMANVTKAFVGDSKDLVDPFVEVSFAGQTGRTSVQKNCADPVWHEQVVFKEMFPPLCRRVKIQVWDEGSMSDVALATHFIDLKKISNEQDGDKGFLPTFGPAWINLYGSPRNQSLMDDYQELNEGFGEGVSFRGRILVEIAVEILSGGAQESKFSKALKELKLPSKDKDSKSSKGSSKDKADKTDDGKAQQAADKTNSTEVEVESFAVPPEIIPEKYEEFLLFGAFFEATMIDRKIGDKPISFEVSIGNFGNLIDGGSHHGSKKKSAELVEEDVLPLLHEGGKDVSHDSVISTSSTTHPEKPLVTEGNRNYSYLPFGAKKPCVSFISSWGDQTFRLHWSNMLGKMADLLEEGIEEVRELVKVSEEAPEEKMKTVLRAFISQSSAFISEAEKKPKMLNQTALDKKRLTLCWQELEAMVKEAKGVIQQQKKKLSVDEMIGEAQGYVEKIRFLVDEPQHTIPDVFIWMLSNNKRVAYARIAAKDLLYSPIPEQVGKYCGKIKTHFLKLPGKRPAGWTVQAKVDIYLWLGSTRYSNAILDNLPAGYEAETPSKASGTHHPPSTLLYQAQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSQCQTTKVISQTLSPTWNQMLLFNELVLHGEERELAESPPLVVVELYDSDAVGKPEYLGATVAAPVVTLANQDYEPPKLCYHPVFCGNLPGGDLLAVFELLQVPSSGLQGLPPIDPPDITQIYPVPSNIRPVLSKYRVEVLFWGVREMKKVQLLSVDRPQVLIECGGRGVKSCVIQSYKNNPNFSVQAEAFDVELPENELLHPPLSICVVDWRAFGRSTLVGTYTINCLKQFLCKSRETLALPSQRDGAWARPDSQGDIEPSRPSSSQDPPADHIYVDVDPPPTVVPDSAQAQTATLADIPDSSPMLEPEHKAVSQEPPKDGKVKQDPRKPSRRSTKRRKRTIADESAENVIDWWSKYDASLKKAQKEKENNTKEKRAMEAKPDEVVLDIDDGPKRKKDKMFKKKLKDEGSDGIPNLAVLKIYDGDLESEFNNFEDWVKTFELFRGKSSEDDHSLDGDRVIGKFKGSFCIYKSPEESTSEDSGQLRIQQGIPPNQPIQVLIRVYIVAAFNLSPADPDGKSDPYIVLRLGKTEIKDRDKYIPKQLNPVFGRSFEIQATLPKESLLSILIYDHDMIGSDDLIGETKIDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPHFHPGKIQIGNQVFSGKTVFTEEDSEEMVESYEHLALKVLHSWEDIPEVGCRLVPEHIESRPLYHKDKPGMEQGRLQMWVDMFPKDTPQLGPPVDISPRKPKGYELRVTIWNTEDVILEDENIFTGQKSSDIYVKGWIKGLEDDRQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQMVITKRENIFSLEKMECKSPAVLVLQVWDFERLSSDDFLGSLEMNLNSFPRAAKSAKACDLSKFENASEENKISIFQQKRVRGWWPFAKSKELTGKVEAEFHLVTAEEAEKNPVGKARKEPEPLAKPNRPDTSFSWFVSPFKCLYHLIWKNYKKYIIIAFILLILVVFLVLFIYTLPGAISRRIVVGGS", "length": 1723, "header": "tr|A0A9J7H643-1|A0A9J7H884_CRIGR Computationally mapped isoform of Fer-1-like protein 6 OS=Cricetulus griseus OX=10029 GN=LOC107977007 PE=3 SV=1 CANONICAL=A0A9J7H884-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H884-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H884/entry#A0A9J7H884-1", "sequence": { "sequence": "MFGLKLKKKKKNKAEKGLILTNKGAQDGQSDSEAPQEGPSHQERPEGDAVQDDTSITPGLSAPLKRRAKLLTKIHDGEVKSQSFQIAITITEARQLVGENIDPVVTIEIGEEKKQSTVKEGTNSPFYNEYFVFDFIGPQVHLFDKIIKISVLHHKLIGSILIGSFRVDVGTVYNQPGHQFCDKWALLTDPGDIRTGTKGYLKCDISVTGKGDVLQTNPKTFDAEEQVEKNLLIPQGFPSERPWARFYVRLYRAEGLPKMNSSIMANVTKAFVGDSKDLVDPFVEVSFAGQTGRTSVQKNCADPVWHEQVVFKEMFPPLCRRVKIQVWDEGSMSDVALATHFIDLKKISNEQDGDKGFLPTFGPAWINLYGSPRNQSLMDDYQELNEGFGEGVSFRGRILVEIAVEILSGGAQESKFSKALKELKLPSKDKDSKSSKGSSKDKADKTDDGKAQQAADKTNSTEVEVESFAVPPEIIPEKYEEFLLFGAFFEATMIDRKIGDKPISFEVSIGNFGNLIDGGSHHGSKKKSAELVEEDVLPLLHEGGKDVSHDSVISTSSTTHPEKPLVTEGNRNYSYLPFGAKKPCVSFISSWGDQTFRLHWSNMLGKMADLLEEGIEEVRELVKVSEEAPEEKMKTVLRAFISQSSAFISEAEKKPKMLNQTALDKKRLTLCWQELEAMVKEAKGVIQQQKKKLSVDEMIGEAQGYVEKIRFLVDEPQHTIPDVFIWMLSNNKRVAYARIAAKDLLYSPIPEQVGKYCGKIKTHFLKLPGKRPAGWTVQAKVDIYLWLGSTRYSNAILDNLPAGYEAETPSKASGTHHPPSTLLYQAQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSQCQTTKVISQTLSPTWNQMLLFNELVLHGEERELAESPPLVVVELYDSDAVGKPEYLGATVAAPVVTLANQDYEPPKLCYHPVFCGNLPGGDLLAVFELLQVPSSGLQGLPPIDPPDITQIYPVPSNIRPVLSKYRVEVLFWGVREMKKVQLLSVDRPQVLIECGGRGVKSCVIQSYKNNPNFSVQAEAFDVELPENELLHPPLSICVVDWRAFGRSTLVGTYTINCLKQFLCKSRETLALPSQRDGAWARPDSQGDIEPSRPSSSQDPPADHIYVDVDPPPTVVPDSAQAQTATLADIPDSSPMLEPEHKAVSQEPPKDGKVKQDPRKPSRRSTKRRKRTIADESAENVIDWWSKYDASLKKAQKEKENNTKEKRAMEAKPDEVVLDIDDGPKRKKDKMFKKKLKDEGSDGIPNLAVLKIYDGDLESEFNNFEDWVKTFELFRGKSSEDDHSLDGDRVIGKFKGSFCIYKSPEESTSEDSGQLRIQQGIPPNQPIQVLIRVYIVAAFNLSPADPDGKSDPYIVLRLGKTEIKDRDKYIPKQLNPVFGRSFEIQATLPKESLLSILIYDHDMIGSDDLIGETKIDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPHFHPGKIQIGNQVFSGKTVFTEEDSEEMVESYEHLALKVLHSWEDIPEVGCRLVPEHIESRPLYHKDKPGMEQGRLQMWVDMFPKDTPQLGPPVDISPRKPKGYELRVTIWNTEDVILEDENIFTGQKSSDIYVKGWIKGLEDDRQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQMVITKRENIFSLEKMECKSPAVLVLQVWDFERLSSDDFLGSLEMNLNSFPRAAKSAKACDLSKFENASEENKISIFQQKRVRGWWPFAKSKELTGKVEAEFHLVTAEEAEKNPVGKARKEPEPLAKPNRPDTSFSWFVSPFKCLYHLIWKNYKKYIIIAFILLILVVFLVLFIYTLPGAISRRIVVGGS", "length": 1861, "header": "tr|A0A9J7H884-1|A0A9J7H884_CRIGR Isoform 1 of Fer-1-like protein 6 OS=Cricetulus griseus OX=10029 GN=LOC107977007 PE=3 SV=1 CANONICAL=A0A9J7H884-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1144, "start_aa": "Thr", "end_pos": 1144, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1144", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H643", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H643" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H643", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H643" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:107977007", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:107977007", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "plasma membrane organization", "id": "GO:0007009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007009", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H884", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H884" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H884", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H884" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H884", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H884" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1043, "end_pos": 1045, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1231, "end_pos": 1233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1370, "end_pos": 1372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1738, "end_pos": 1740, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 659, "end_pos": 661, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H884", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H884" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 185, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1144 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1043, "end_pos": 1045 }, { "start_pos": 1231, "end_pos": 1233 }, { "start_pos": 1370, "end_pos": 1372 }, { "start_pos": 1738, "end_pos": 1740 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 266, "end_pos": 268 }, { "start_pos": 374, "end_pos": 376 }, { "start_pos": 459, "end_pos": 461 }, { "start_pos": 572, "end_pos": 574 }, { "start_pos": 659, "end_pos": 661 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H645-1", "uniprot_ac": "A0A9J7H645", "uniprot_id": "A0A9J7H645_CRIGR", "mass": { "chemical_mass": 43303.0, "monoisotopic_mass": 43303.0 }, "refseq": { "ac": "XP_035305028", "name": "zinc finger protein 615-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305028" }, "gene_names": [ { "name": "LOC113830935", "type": "recommended", "evidence": [ { "id": "A0A9J7H645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H645" } ] }, { "name": "LOC113830935", "type": "synonym", "evidence": [ { "id": "XP_035305028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305028" } ] } ], "protein_names": [ { "name": "Zinc finger protein 615-like isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H645/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 615-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305028" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 14% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305028", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305028" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H645", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H645#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H645", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H645" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113830935", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H645", "locus": {} } ], "crossref": [ { "id": "A0A9J7H645", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H645", "database": "AlphaFoldDB", "categories": [] }, { "id": "113830935", "url": "https://www.ncbi.nlm.nih.gov/gene/113830935", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113830935", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113830935", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H645", "url": "https://www.orthodb.org/?gene=A0A9J7H645", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19818:SF158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19818:SF158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305028", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305028", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H645", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H645", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H645-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H645-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSSTVWHKAMSGWSIVSKRKVTIDTGSLRKAFSTKSSLTAHQEIHMGDKPYICSECGKGFIEKRRLVGHHRTHTGEKPFICSKCGKGFTLKDSLITHQQTHTGEKPYTCSECGKSFSLKSHLVIHHRIHTGEKPYVCNECGKGFPTKVQLIIHQQTHTGDKPYTCHDCGKGSALKNRLIVHQRTHTGEKPYVCNECGKGFLTKTRLIIHQRTHTGAKPYKCNRCGKGFPEKSQLNVHQRTHTGEKPYVCSQCGKGLSEKKMLIAHQRAHNGEKPYLCNECGNGFMMKSTLSIHQQTHIGEKPYKCNECSKGFLHKNDLITHQRIHTGEKPYECNECGKAFTTKSWLNVHQRTHTGERPYGCCDCEKAFTHLSTLVKHKRIHC", "length": 383, "header": "tr|A0A9J7H645-1|A0A9J7H645_CRIGR Isoform 1 of Zinc finger protein 615-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC113830935 PE=3 SV=1 CANONICAL=A0A9J7H645-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H645-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H645/entry#A0A9J7H645-1", "sequence": { "sequence": "MGSSTVWHKAMSGWSIVSKRKVTIDTGSLRKAFSTKSSLTAHQEIHMGDKPYICSECGKGFIEKRRLVGHHRTHTGEKPFICSKCGKGFTLKDSLITHQQTHTGEKPYTCSECGKSFSLKSHLVIHHRIHTGEKPYVCNECGKGFPTKVQLIIHQQTHTGDKPYTCHDCGKGSALKNRLIVHQRTHTGEKPYVCNECGKGFLTKTRLIIHQRTHTGAKPYKCNRCGKGFPEKSQLNVHQRTHTGEKPYVCSQCGKGLSEKKMLIAHQRAHNGEKPYLCNECGNGFMMKSTLSIHQQTHIGEKPYKCNECSKGFLHKNDLITHQRIHTGEKPYECNECGKAFTTKSWLNVHQRTHTGERPYGCCDCEKAFTHLSTLVKHKRIHC", "length": 383, "header": "tr|A0A9J7H645-1|A0A9J7H645_CRIGR Isoform 1 of Zinc finger protein 615-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC113830935 PE=3 SV=1 CANONICAL=A0A9J7H645-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H645", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H645" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H645", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H645" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H645", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H645" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H645", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H645" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H645", "url": 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} ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305606" } ] } ], "protein_names": [ { "name": "Tip-associated protein", "type": "recommended", "evidence": [ { "id": "A0A9J7H651", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H651/entry#names_and_taxonomy" } ] }, { "name": "Tip-associating protein", "type": "synonym", "evidence": [ { "id": "A0A9J7H651", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H651/entry#names_and_taxonomy" } ] }, { "name": "mRNA export factor TAP", "type": "synonym", "evidence": [ { "id": "A0A9J7H651", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H651/entry#names_and_taxonomy" } ] }, { "name": "nuclear RNA export factor 2", "type": "synonym", "evidence": [ { "id": "XP_035305606", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305606" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305606", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305606" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H651", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H651" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100765765", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H651", "locus": {} } ], "crossref": [ { "id": "A0A9J7H651", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H651", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14342", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14342", "database": "CDD", "categories": [ "Protein 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"categories": [ "Protein Classification" ] }, { "id": "IPR030217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765765", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765765", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H651", "url": 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"MDGHSVFQGRKRSSNYIGHKFDRKNHHLGHPGTPYASRPKRRRIKYSDEDQSFPSVWEDDKQQESELGLGARNRNLDSWFKVTIPNGKKYDKTWLIKSIQDFCSVPLNVVDFHYDKKRARFFVQNARTASALKDISNKICDETSQKIPILVTPSIVPYSVQNKFTSEQMEVLKVAVMKRYDASQKSLDLQRFRFDQDLMDNDIDMMLNRRSCMIATLQIVQRNIPELLALNVCNNKLYQLDGLSDLIEKAPQVKILNLSRNKLKSFFELEKVKDLNLEELWLEGNPFCNHVSDQSDYISAIRDLFPKLLRLDGKELILPAELILPAQMDIEVPQETRTDSELIKNLVLQFLKEYYLCYDNGDRFRLLDAYHDEACFSLAIPFNFNDPDMSNLEEYFKYNRDIKKLQDSYTRMRLLKHTKQDIVDSLSLLPKTQHDFCSFWVDLCLHTDIMLCFSVNGLFKEVEGKCQGCIRAFTRIFIATHYSNSRICIMNDELIVRNASPREIKNAFISLPPADTSSKPPLSEEQQEMVKSFSVQSGMKLNWSQKCLEDNGWDYTKAAEVFTIMQNEDKIPKEFFK", "length": 577, "header": "tr|A0A9J7H651-1|A0A9J7H651_CRIGR Isoform 1 of Tip-associated protein OS=Cricetulus griseus OX=10029 GN=LOC100765765 PE=3 SV=1 CANONICAL=A0A9J7H651-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H651-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H651/entry#A0A9J7H651-1", "sequence": { "sequence": "MDGHSVFQGRKRSSNYIGHKFDRKNHHLGHPGTPYASRPKRRRIKYSDEDQSFPSVWEDDKQQESELGLGARNRNLDSWFKVTIPNGKKYDKTWLIKSIQDFCSVPLNVVDFHYDKKRARFFVQNARTASALKDISNKICDETSQKIPILVTPSIVPYSVQNKFTSEQMEVLKVAVMKRYDASQKSLDLQRFRFDQDLMDNDIDMMLNRRSCMIATLQIVQRNIPELLALNVCNNKLYQLDGLSDLIEKAPQVKILNLSRNKLKSFFELEKVKDLNLEELWLEGNPFCNHVSDQSDYISAIRDLFPKLLRLDGKELILPAELILPAQMDIEVPQETRTDSELIKNLVLQFLKEYYLCYDNGDRFRLLDAYHDEACFSLAIPFNFNDPDMSNLEEYFKYNRDIKKLQDSYTRMRLLKHTKQDIVDSLSLLPKTQHDFCSFWVDLCLHTDIMLCFSVNGLFKEVEGKCQGCIRAFTRIFIATHYSNSRICIMNDELIVRNASPREIKNAFISLPPADTSSKPPLSEEQQEMVKSFSVQSGMKLNWSQKCLEDNGWDYTKAAEVFTIMQNEDKIPKEFFK", "length": 577, "header": "tr|A0A9J7H651-1|A0A9J7H651_CRIGR Isoform 1 of Tip-associated protein OS=Cricetulus griseus OX=10029 GN=LOC100765765 PE=3 SV=1 CANONICAL=A0A9J7H651-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 152, "start_aa": "Thr", "end_pos": 152, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr152", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H651", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H651" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H651", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H651" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765765", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765765", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "poly(A)+ mRNA export from nucleus", "id": "GO:0016973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016973", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H651", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H651" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H651", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H651" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H651", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H651" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H651", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H651" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H651", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H651" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H651", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H651" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 542, "end_pos": 544, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H651", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H651" }, { "id": "PS50177", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50177" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NTF2", "eco_id": "ECO_0000259", "start_pos": 346, "end_pos": 496, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H651", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H651" }, { "id": "PS51281", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51281" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TAP-C", "eco_id": "ECO_0000259", "start_pos": 524, "end_pos": 577, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 152 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 257, "end_pos": 259 }, { "start_pos": 498, "end_pos": 500 }, { "start_pos": 542, "end_pos": 544 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H663-1", "uniprot_ac": "A0A9J7H663", "uniprot_id": "A0A9J7H663_CRIGR", "mass": { "chemical_mass": 97329.0, "monoisotopic_mass": 97329.0 }, "refseq": { "ac": "XP_035305059", "name": "leukocyte immunoglobulin-like receptor subfamily B member 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305059" }, "gene_names": [ { "name": "LOC113837258", "type": "recommended", "evidence": [ { "id": "A0A9J7H663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H663" } ] }, { "name": "LOC113837258", "type": "synonym", "evidence": [ { "id": "XP_035305059", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305059" } ] } ], "protein_names": [ { "name": "Leukocyte immunoglobulin-like receptor subfamily B member 3 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H663/entry#names_and_taxonomy" } ] }, { "name": "leukocyte immunoglobulin-like receptor subfamily B member 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305059", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305059" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 58% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305059", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305059" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H663", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H663" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113837258", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H663", "locus": {} } ], "crossref": [ { "id": "A0A9J7H663", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H663", "database": "AlphaFoldDB", "categories": [] }, { "id": "113837258", "url": "https://www.ncbi.nlm.nih.gov/gene/113837258", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113837258", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837258", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H663", "url": "https://www.orthodb.org/?gene=A0A9J7H663", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11738:SF179", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11738:SF179", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305059", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305059", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H663", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H663", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H663-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H663-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHQVQKAPGSGDRAPVSGQTLTGNSIAGLSLNIRIPVLAGALFKPTLRTVPSNVVATGNQVTFFCEGPLDTKEYRLYKEGSQDYLLPTTILETDNRGTFSISSVQWYNAGQYWCEYKSSNETSEHSDMLQLVVTGVHPSNPILSAIPSPVVASGGNVTLQCESQGMYNTFVLMKDDKKFSSQVPSQNMYPKAVFTVGPVTANQRWRFTCYGYLGSSPQLWSLPSNHLELLVSGKCKKPTLSAEPGSVIALKNDVTVLCEGTKETQIYFLHKEGSPVPLDSQTPKQPGNKALFSIASIERHHAGKYRCYSYGSAGWSQHSDPLELAVTGFYSSKVTLSALPSPVVISGQHVTLQCVSQQAYNGFILLKEDQKFSRPVSSQNRHHGLSGGHFRVGPVTHNQRWRFTCYGYYLNNPQLWSVSSNALELLVSGNLHKPSIWAHPGSVVSSGSSVTIWCWGTQQTLTYVIHKEGSPEPSHIETQVDHNNKAKFSLPSVSSLNAGRYNCYSYSSAGWTERSDTLELVVTGVHDDKPTLSALPSPVVTSGGNVSLQCISFKGYDGFILTGADLKFPRSQKAQFINKGKSQALFPEISVTYSKNGPFRCYGYYTNTSYVWSEASNPLEIHVSGLSRKPYLVTQQETVLAPGENLTLKCFSETNYDRFALYKEGEHDLTQVSACQPQDGHFHTNFTVGSGNYFIGGRYRCLGAHSNSSEWSAPSDPLDILITGHPLVALNLSVHPGPTVSSGENVTLLCQSSVPVDTFFLFKEGEAHPYMQQSSQSQDPQHEAKFFMSAVTLDLGGSYICLGSERLSPFLLSHSSVPVEITVSGPARHQKAVIGVSVVLFLLLFLLILFLLRLRHQTKDRKGAQTKTHMQPPADSVTRDKSLQKR", "length": 887, "header": "tr|A0A9J7H663-1|A0A9J7H663_CRIGR Isoform 1 of Leukocyte immunoglobulin-like receptor subfamily B member 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC113837258 PE=4 SV=1 CANONICAL=A0A9J7H663-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H663-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H663/entry#A0A9J7H663-1", "sequence": { "sequence": 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H683-1", "uniprot_ac": "A0A9J7H683", "uniprot_id": "A0A9J7H683_CRIGR", "mass": { "chemical_mass": 184853.0, "monoisotopic_mass": 184853.0 }, "refseq": { "ac": "XP_035303919", "name": "ATP-binding cassette sub-family A member 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303919" }, "gene_names": [ { "name": "Abca6", "type": "recommended", "evidence": [ { "id": "A0A9J7H683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H683" } ] }, { "name": "Abca6", "type": "synonym", "evidence": [ { "id": "XP_035303919", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303919" } ] } ], "protein_names": [ { "name": "ATP-binding cassette sub-family A member 6", "type": "synonym", "evidence": [ { "id": "XP_035303919", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303919" }, { "id": "A0A9J7H683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H683/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303919", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303919" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H683", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H683" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Abca6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H683", "locus": {} } ], "crossref": [ { "id": "cd03263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772341", "url": "https://www.ncbi.nlm.nih.gov/gene/100772341", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056264", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056264", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772341", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772341", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ITSQIVF", "url": "https://omabrowser.org/oma/group/ITSQIVF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H683", "url": "https://www.orthodb.org/?gene=A0A9J7H683", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19229", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19229", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19229:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19229:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12698", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12698", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23321", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23321", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26955", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26955", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303919", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303919", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H683", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H683", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H683-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H683-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTMKEISVYQQTRALLHKNLLKKWRMKRESFLEWSIPIIVGLYMGLFSYFKENMQFPEIPPKDLGSVDEFNGSSIMVVYTPISNITQLIMNKTTLAPSMKGTTIIGVPSKKDLDEVLLNSIPHALGIIFNDTFSYKLEVFLMYGNPFLKEDLLAHCWDIYGDISCSLSRYWKKGFVPLQTAINAAIIEITTNHSVMEELMSVNAVTMKTLPFITKDIFQYEFFILFCLLYFSSFMYFISRNVTKERKKYKELMKIMGLQDSAFWLSWGLIYVGFIFIISIFIAIIITSAKIIVMTGFLVIFTLFFLYGLSLITVAFLMAVLLQKAILTNLVIFLFTLFWGCVGFTVLHKQLPTSLEWILSICSPFAFTSGMAKIISLDYNLNGVVFPDPSGESYLILVTFSILAFDALIYFVLALYFDKILPYGNEHSYSPLFFLNSSSCLQQKSSSNQVLERGIDPELPSDDSFEPVAPEYQGKEAIRIRNIKKEYKGKSGKVEALKGLFLDIYESQITAILGRSGAGKSSLLNILNGLYVPTSGLVTVYNKNLSEMQDLKEIRRITGVCPQHNVQFDALTVKENLTLFAKIKGILPQKVKQEVQQIILELDMQNIQDNLVEHLSEGQKRKLTFGIATLGDPQILLLDEPTVGLDPFSRQRVWSFLKERKANRVILFSTQFMDEADILADRKVILSNGSLKCTGSSVFLKRKWGLGYHLSLFIDETCDLEQITSSINHHIPDAKLKAKTKEKLVYILPLERTSKFPDFFRDLDKYSDQGLVNYEVSMSTLNEAFMNMEGESTTKQNFEKRETIRDTESLQEMEPAYPSLSEVQRTVSPMKLWGMQVCAIARLRILKLKRERKAFLTFLLIFGIALFPLIMEKMANAVIEQKNDWEFKTELYFLSPGQLPEGLRTSLLVINNTESNIEDFIQSLKHQNIVLEVDDFENRNGTESLSYNGAIIVSGRQKDYRFSVVCNTKRLHCFPILMNVLSNGILHMLNHTQYIRIEEAVFSSDLIMLWFGILEGLLFLLLVACSISPHIAMSSVSDYKKKADSQLWISGLYPSAYWCGQAVVDINLFNVILLSSYFTLHVTKLMHIYLTSEVVLSIVVVLFGCAASLVFLTYVISFVFGKRRKNSGLWSICFFTVMAVMFKILLTEFFSETLLIIMMVLVPSFSLIAFLIFLEMRSFQHYSEFGEIKYGLSGVDLLLCLIPYFHTLLFIFVLRCLELKCGKNVMRKDPIFRISPRSVKVQPNLEEHIGEDEDEDEDVQAERIRTSAALSTSNLNERPVIIANGLYKEYAGQKKCCFSKRTKKVAARNISFCVNKGEILGLLGPNGAGKTSSVRMIAGITKPAAGEVELKGSSSAVGYQGDGTIKFGYCPQENMLWPILTVKEHLQVYASVKGLRKKDATIAISRLVNAFKLHDQLNVLVQKLAAGATRKLCFVLSILGDSSILILDEPSTGLDVSEQQQVWQAIQAAVKDNDRGVLLTTHDLAEAEALCDRVAIMVSGRLRCIGSIQHLKRKFGKDYILELKVNETSQVPLVHRDIVKLFPQAARQERYFSLLTYQLPITDVYPLSQAFHKLEAVKHSFNLEEYSLSQCTLDKVFLELSKDQELETVHEEADTTVRWKLLPRLDEL", "length": 1628, "header": "tr|A0A9J7H683-1|A0A9J7H683_CRIGR Isoform 1 of ATP-binding cassette sub-family A member 6 OS=Cricetulus griseus OX=10029 GN=Abca6 PE=3 SV=1 CANONICAL=A0A9J7H683-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H683-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H683/entry#A0A9J7H683-1", "sequence": { "sequence": "MTMKEISVYQQTRALLHKNLLKKWRMKRESFLEWSIPIIVGLYMGLFSYFKENMQFPEIPPKDLGSVDEFNGSSIMVVYTPISNITQLIMNKTTLAPSMKGTTIIGVPSKKDLDEVLLNSIPHALGIIFNDTFSYKLEVFLMYGNPFLKEDLLAHCWDIYGDISCSLSRYWKKGFVPLQTAINAAIIEITTNHSVMEELMSVNAVTMKTLPFITKDIFQYEFFILFCLLYFSSFMYFISRNVTKERKKYKELMKIMGLQDSAFWLSWGLIYVGFIFIISIFIAIIITSAKIIVMTGFLVIFTLFFLYGLSLITVAFLMAVLLQKAILTNLVIFLFTLFWGCVGFTVLHKQLPTSLEWILSICSPFAFTSGMAKIISLDYNLNGVVFPDPSGESYLILVTFSILAFDALIYFVLALYFDKILPYGNEHSYSPLFFLNSSSCLQQKSSSNQVLERGIDPELPSDDSFEPVAPEYQGKEAIRIRNIKKEYKGKSGKVEALKGLFLDIYESQITAILGRSGAGKSSLLNILNGLYVPTSGLVTVYNKNLSEMQDLKEIRRITGVCPQHNVQFDALTVKENLTLFAKIKGILPQKVKQEVQQIILELDMQNIQDNLVEHLSEGQKRKLTFGIATLGDPQILLLDEPTVGLDPFSRQRVWSFLKERKANRVILFSTQFMDEADILADRKVILSNGSLKCTGSSVFLKRKWGLGYHLSLFIDETCDLEQITSSINHHIPDAKLKAKTKEKLVYILPLERTSKFPDFFRDLDKYSDQGLVNYEVSMSTLNEAFMNMEGESTTKQNFEKRETIRDTESLQEMEPAYPSLSEVQRTVSPMKLWGMQVCAIARLRILKLKRERKAFLTFLLIFGIALFPLIMEKMANAVIEQKNDWEFKTELYFLSPGQLPEGLRTSLLVINNTESNIEDFIQSLKHQNIVLEVDDFENRNGTESLSYNGAIIVSGRQKDYRFSVVCNTKRLHCFPILMNVLSNGILHMLNHTQYIRIEEAVFSSDLIMLWFGILEGLLFLLLVACSISPHIAMSSVSDYKKKADSQLWISGLYPSAYWCGQAVVDINLFNVILLSSYFTLHVTKLMHIYLTSEVVLSIVVVLFGCAASLVFLTYVISFVFGKRRKNSGLWSICFFTVMAVMFKILLTEFFSETLLIIMMVLVPSFSLIAFLIFLEMRSFQHYSEFGEIKYGLSGVDLLLCLIPYFHTLLFIFVLRCLELKCGKNVMRKDPIFRISPRSVKVQPNLEEHIGEDEDEDEDVQAERIRTSAALSTSNLNERPVIIANGLYKEYAGQKKCCFSKRTKKVAARNISFCVNKGEILGLLGPNGAGKTSSVRMIAGITKPAAGEVELKGSSSAVGYQGDGTIKFGYCPQENMLWPILTVKEHLQVYASVKGLRKKDATIAISRLVNAFKLHDQLNVLVQKLAAGATRKLCFVLSILGDSSILILDEPSTGLDVSEQQQVWQAIQAAVKDNDRGVLLTTHDLAEAEALCDRVAIMVSGRLRCIGSIQHLKRKFGKDYILELKVNETSQVPLVHRDIVKLFPQAARQERYFSLLTYQLPITDVYPLSQAFHKLEAVKHSFNLEEYSLSQCTLDKVFLELSKDQELETVHEEADTTVRWKLLPRLDEL", "length": 1628, "header": "tr|A0A9J7H683-1|A0A9J7H683_CRIGR Isoform 1 of ATP-binding cassette sub-family A member 6 OS=Cricetulus griseus OX=10029 GN=Abca6 PE=3 SV=1 CANONICAL=A0A9J7H683-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H683", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H683" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H683", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H683" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772341", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772341", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "M0R890-1", "protein_name": "ATP binding cassette subfamily A member 6", "gene_name": "Abca6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSMKELSVRQQTRVLLHKNLLKKWRMKRESLLEWSIPVVIGLYMGLFSYFKENNQVPEVPPQDLGSIDEFNGSSIMVVYTPISNVTQQIMNKTITAPTMKGTRIVGVPSEKDLDEMLLDHVPRAFGIVFNDTFFYKLKVYLMYGNPFLKEDLLAHCWDTYPHVFCSLTRYWKRGFVALQTAINAAIIEVTTKHPVMEELMSVNAFNMKTLPFISKDIFQYEIFILFCLLYFSSFIYFASRSVTKERKHSKEFMKVMGLQDSAFWLSWGLIYVGFIFIFSVFIAVIITSTRIIVMTGFLVIFTLFFLYGLSVIAVTFLMAVLLQKAIITNLFVFLFNLFWGCVGFTVLHKELPSSLEWVLSICSPFAFTSGMTKIIFLEYNLNGVVFPDPSGESYVMIAVFFILAFDGLLYLVLALYFDKILPCGADRRAAPLFFLNPVSCFRKRTSRNKVTERDIDPELPSDEYFEPVDPEYQGKEAIRIRNIRKEYKGKSGKVEALKGLFFDVYESQITAVLGHGGAGKSSLLNILNGLSVPTSGLATVYNKNLSEMQDLKEIRKMIGVCPQHNVQFDALTVKENLTLFANIKGIVPQSVAQEVQQILSELDMQTIQDELAEHLSEGQKRKLTFGVAILGDPRILLLDEPTAGLDPFSRQRVWGFLKERRADRVILFSTQFTDEADILADRKVILSNGALKCTGSSVFLKRKWGLGYHLSLFMNETCDSEQLTSFINHHIPGAKLKAKTKEKLVYTLPLEKTSKFPEFFSDLDKYSGQGLMNYEVSMSTLNEVFMNLEGEPSTTQDFEKGETLTDSDSLNEMEVAPPSLSKAQKTMSAMSLWRMQVCAIARLRVLKLRRERKAFLTFLPLLGISLIPLITEYMANALIEVKTNWEFKTDLYFLSPGQLPQGLRTSLLVINNTESNIEDFVQSLKHQNIVLEVDDFENRNATESLSYNGAIIVSGRQKDYRFSAVCNTKRLHCFPILMNVISNGILRMLNHTQHIRLEEDVLSSGIVVVWFGILEASLSILFIVCSVSPHIAMSSISDFKKKADSQLWISGLYPSAYWCGQALVDITLLSGILLTGYITLYTTKLMHIYLTGEIVLSIVLLAFGCAASLVFLTYVISFVFGKKRKNSGLWSICFFIVITIMFDTVLMDPFNEALLISAMMLVPSFSLNALLIVLEMRAYQYYREFGESKYGLSGVDLLLCLIPYFHTLLFIFVLRCLELKYGKNVVRKDPLFRIAPQSLHVQPNPEEPVDEDEDVQAERMRTSDALSTVNLDEKPAIIASCLHKEYTGQKKWCCSKRRKKIAVRNISFCVNKGEILGLLGPEGAGKSSSLRMIAGIMKPTAGEVELKELSSAVAHQGEGHGAAKLGYCPQENVLWPILTVKEHLEVYAAVKGLRKKDAVIAISRLVNAFKLHDQLNVQARNLVVGLTRKLCFALSILGNSPVLILDEPSTGLDVSGKQQMWQAIQAAVKDNKKGVLLSTHDLAEAEALCDRAAIMVSGRLRLIGSIQHLKRRFGKDYILELRVKEISQEPLVHKEILRLFPQAARQDRCFSLLTYKLPVTDVHPLSQAFHKLEAVKRGFNLDDYSLSQCTLDRVFLELSKEQELGDVHEEADITMRWKLLPPSDEL", "length": 1627 }, "evidence": [ { "id": "A0A9J7H683", "url": "https://omabrowser.org/oma/group/A0A9J7H683/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K441-1", "protein_name": "ATP-binding cassette sub-family A member 6", "gene_name": "Abca6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKELSVHVRQQTRALLHKILLKKWRRKRESLLEWSIPIIIGLHMGLFSYLARNIQVLEVPPQDLGSLNEFNGSSLVVVYTPISNITQQIMNKTTFAPTMKGTRIIGVPSIEDLDEVLLHNIPDALGVIFNDSFSYQLKVLRMYGNPFLKEDLLAHCWDTHSQAFCSLSKYWERGFVALQTAINAGIIEVTTNHSVMEELMSIDGINMKTLPFIPRDLSDYEIFILFCLLYFSSFIYFASSNVTKERKQCKEVMKVMGLQDSAFWLSWGLIYVGFIFIISIFIAIIITSTQIIMMTGFLVIFTLFFLYGLSLIAVTFLMAVLLQKAVLTNLIVLFFTLFWGCVGFTVLHKELPPSLEWVLSIFSPFAFTSGMAKVIFQDYNLNGVVFPDPSGESYVMIAVFFILAFDSLLYLVLALYFDKILLYGAEHRSAPLFFLNPTSCFRKTANRNKVIERDLDPELPSDEYFEPVDPEYQGKEAIRIRNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKAIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADILADRKVLIANGALKCTGSSVFLKRKWGLGYHLSLFMDETCDSERLTSFINHHIPYAKLKAKTKEKLVYILPLERTSEFPEFFSDLDKYSGQGLMSYEVSMSTLNDVFLNLEGEPSTKQDFEKRETATDSESLNDMEVAYPSLSQVQETVSTMSLWRMQVCAIARLRILKLKRERKAFLIILLLLGIALLPLVIEYVANALLEVKNNWEFKTDLYFLSPGQLPQGLRTSLLVINNTESNIEDFLQSLKHQNIVLEVDDFENRNATNSLSYNGAIIVSGRQKDYRFSAVCNTKRLHCFPILMNVISNGILHMLNHTQYIRIKEDIFSPFIVLVWTGIQETCLFILCVICSLSPHIAMSSVSDYKKKADSQLWISGLYPSAYWCGQAVVDISLFSGMLLTSYFTSYTSKLLNIDMTSEIVFSVIVLALGCAASLVFLTYVISFVFGKRKKNSTLWSICFLLVIAITFEKVANGPFNEALVISATMLVPSFALNGLLVVLEMRAYQYYIEFEEIKHGLSAVDLLLCLIPYIHTLLFIFVLRCLELKYGKNVVRRDPIFRIAPQSLKAQPNPEEPIDEDENVQAERLRTSDALSTPNLDEKPVIIASCLHKEYAGQKKHCCSRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRKFGQDYVLELRVKDVSQEPLVHREILKLFPQAARQDRCFSLLTYKLPVTDVHPLSQAFHKLEAVKHGFDLEDYSLSQCTLDRVILELSKEQELGTVYEEADMTLGRKLLPPSDEL", "length": 1624 }, "evidence": [ { "id": "A0A9J7H683", "url": "https://omabrowser.org/oma/group/A0A9J7H683/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N139-1", "protein_name": "ATP-binding cassette sub-family A member 6", "gene_name": "ABCA6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNMKQKSVYQQTKALLCKNFLKKWRMKRESLLEWGLSILLGLCIALFSSSMRNVQFPGMAPQNLGRVDKFNSSSLMVVYTPISNLTQQIMNKTALAPLLKGTSVIGAPNKTHMDEILLENLPYAMGIIFNETFSYKLIFFQGYNSPLWKEDFSAHCWDGYGEFSCTLTKYWNRGFVALQTAINTAIIEITTNHPVMEELMSVTAITMKTLPFITKNLLHNEMFILFFLLHFSPLVYFISLNVTKERKKSKNLMKMMGLQDSAFWLSWGLIYAGFIFIISIFVTIIITFTQIIVMTGFMVIFILFFLYGLSLVALVFLMSVLLKKAVLTNLVVFLLTLFWGCLGFTVFYEQLPSSLEWILNICSPFAFTTGMIQIIKLDYNLNGVIFPDPSGDSYTMIATFSMLLLDGLIYLLLALYFDKILPYGDERHYSPLFFLNSSSCFQHQRTNAKVIEKEIDAEHPSDDYFEPVAPEFQGKEAIRIRNVKKEYKGKSGKVEALKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDILTVKENLSLFAKIKGIHLKEVEQEVQRILLELDMQNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVWSLLRERRADHVILFSTQSMDEADILADRKVIMSNGRLKCAGSSMFLKRRWGLGYHLSLHRNEICNPEQITSFITHHIPDAKLKTENKEKLVYTLPLERTNTFPDLFSDLDKCSDQGVTGYDISMSTLNEVFMKLEGQSTIEQDFEQVEMIRDSESLNEMELAHSSFSEMQTAVSDMGLWRMQVFAMARLRFLKLKRQTKVLLTLLLVFGIAIFPLIVENIMYAMLNEKIDWEFKNELYFLSPGQLPQEPRTSLLIINNTESNIEDFIKSLKHQNILLEVDDFENRNGTDGLSYNGAIIVSGKQKDYRFSVVCNTKRLHCFPILMNIISNGLLQMFNHTQHIRIESSPFPLSHIGLWTGLPDGSFFLFLVLCSISPYITMGSISDYKKNAKSQLWISGLYTSAYWCGQALVDVSFFILILLLMYLIFYIENMQYLLITSQIVFALVIVTPGYAASLVFFIYMISFIFRKRRKNSGLWSFYFFFASTIMFSITLINHFDLSILITTMVLVPSYTLLGFKTFLEVRDQEHYREFPEANFELSATDFLVCFIPYFQTLLFVFVLRCMELKCGKKRMRKDPVFRISPQSRDAKPNPEEPIDEDEDIQTERIRTATALTTSILDEKPVIIASCLHKEYAGQKKSCFSKRKKKIAARNISFCVQEGEILGLLGPNGAGKSSSIRMISGITKPTAGEVELKGCSSVLGHLGYCPQENVLWPMLTLREHLEVYAAVKGLRKADARLAIARLVSAFKLHEQLNVPVQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERGVLLTTHNLAEAEALCDRVAIMVSGRLRCIGSIQHLKNKLGKDYILELKVKETSQVTLVHTEILKLFPQAAGQERYSSLLTYKLPVADVYPLSQTFHKLEAVKHNFNLEEYSLSQCTLEKVFLELSKEQEVGNFDEEIDTTMRWKLLPHSDEP", "length": 1617 }, "evidence": [ { "id": "A0A9J7H683", "url": "https://omabrowser.org/oma/group/A0A9J7H683/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H683", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H683" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H683", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H683" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H683", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H683" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H683", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H683" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H683", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H683" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1309, "end_pos": 1311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1526, "end_pos": 1528, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 688, "end_pos": 690, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" }, { "start_pos": 911, "end_pos": 913, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" }, { "start_pos": 940, "end_pos": 942, "annotation": "n_glycosylation_sequon" }, { "start_pos": 990, "end_pos": 992, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H683" }, { "id": "PS50893", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transporter", "eco_id": "ECO_0000259", "start_pos": 478, "end_pos": 713, "start_aa": "Ile", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1309, "end_pos": 1311 }, { "start_pos": 130, "end_pos": 132 }, { "start_pos": 1526, "end_pos": 1528 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 241, "end_pos": 243 }, { "start_pos": 436, "end_pos": 438 }, { "start_pos": 544, "end_pos": 546 }, { "start_pos": 576, "end_pos": 578 }, { "start_pos": 688, "end_pos": 690 }, { "start_pos": 71, "end_pos": 73 }, { "start_pos": 84, "end_pos": 86 }, { "start_pos": 911, "end_pos": 913 }, { "start_pos": 91, "end_pos": 93 }, { "start_pos": 940, "end_pos": 942 }, { "start_pos": 990, "end_pos": 992 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H689-1", "uniprot_ac": "A0A9J7H689", "uniprot_id": "A0A9J7H689_CRIGR", "mass": { "chemical_mass": 95046.0, "monoisotopic_mass": 95046.0 }, "refseq": { "ac": "XP_035303756", "name": "uncharacterized protein LOC100768826", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303756" }, "gene_names": [ { "name": "LOC100768826", "type": "recommended", "evidence": [ { "id": "A0A9J7H689", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H689" } ] }, { "name": "LOC100768826", "type": "synonym", "evidence": [ { "id": "XP_035303756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303756" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC100768826", "type": "synonym", "evidence": [ { "id": "A0A9J7H689", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H689/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC100768826", "type": "synonym", "evidence": [ { "id": "XP_035303756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303756" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303756", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303756" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H689", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H689" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100768826", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H689", "locus": {} } ], "crossref": [ { "id": "A0A9J7H689", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H689", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04104", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04104", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768826", "url": "https://www.ncbi.nlm.nih.gov/gene/100768826", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030385", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030385", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768826", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768826", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H689", "url": "https://www.orthodb.org/?gene=A0A9J7H689", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32341", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32341", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32341:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32341:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05049", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05049", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303756", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303756", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H689", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H689", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H689-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H689-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQTSSSTPPQKEDPNSTSSLGSDLHNFRMETKILSQELATLIGSYLEDGNLRGTVSAISNALIDIENAPLNIAVMGEIGAGKSSLINALQGVGPDEEGAAASTGVICTTTERAPYPYAKLPSVTLWDLPGIGSTAFQPHDYLKKIKFEEYDFFIIVSSGRFKHNDAELAKAIVQVNRSFYFVRTHTDHDLMVHKQCSPRRFNRENVLKQIRNTISSMLKEITQQEPPVFLVSNFDVSDFDFPKLETTLLKDLPAHKRHIFMLTLPSVTHSTIDQKRDTMKQKVWKESVMPRAWTNIPFRGLTKNDVEKLEETLNLCRSSFGLDETSLVNIAEDTYVTLEELKANIKSPHLFSEEQGKSLTDKLLEYISNPYFSKVFHLQNYFIDTVANDVKILLSKEELFTEKHLLLQTATHKPSRPSPSTAQLLASSFENFFKNFKKESKILSEETIALIESHLENKNLPGAVSAISDALRNVDRAPLNIAVTGETGAGKSSFINALKGVWDEKEGAAPTGVTETTMKRTPYTHPKLPTVTIWDLPGIGSTSFPLQNYLTEMKFAEYDFFVIISATRFKDTDAHLAKAIAKMNTKFYFVRTKIDHDLDNERRSKSKTFNRHSVLKKIRDDYSKHLKEALSSEPRIFLVSNFDVSDFDFPELETTLLGELPAHKRHIFMLSLHSVTESAIDRKRDFLKQKIWLEALKAGAWATIPLGGLVRDKIQKVEETLDLYRSYFGLDDASLENIAKDFNVSVNEIKAHLKSFHLLTRAKDMSLEEKLLKYIEYISSVTGGPLATGLYFRKTFYLKSLFIDTVSSDAKTLLNKEEFLSKKVGSCMSDDTEYWEALTEP", "length": 842, "header": "tr|A0A9J7H689-1|A0A9J7H689_CRIGR Isoform 1 of Uncharacterized protein LOC100768826 OS=Cricetulus griseus OX=10029 GN=LOC100768826 PE=3 SV=1 CANONICAL=A0A9J7H689-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H689-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H689/entry#A0A9J7H689-1", "sequence": { "sequence": "MGQTSSSTPPQKEDPNSTSSLGSDLHNFRMETKILSQELATLIGSYLEDGNLRGTVSAISNALIDIENAPLNIAVMGEIGAGKSSLINALQGVGPDEEGAAASTGVICTTTERAPYPYAKLPSVTLWDLPGIGSTAFQPHDYLKKIKFEEYDFFIIVSSGRFKHNDAELAKAIVQVNRSFYFVRTHTDHDLMVHKQCSPRRFNRENVLKQIRNTISSMLKEITQQEPPVFLVSNFDVSDFDFPKLETTLLKDLPAHKRHIFMLTLPSVTHSTIDQKRDTMKQKVWKESVMPRAWTNIPFRGLTKNDVEKLEETLNLCRSSFGLDETSLVNIAEDTYVTLEELKANIKSPHLFSEEQGKSLTDKLLEYISNPYFSKVFHLQNYFIDTVANDVKILLSKEELFTEKHLLLQTATHKPSRPSPSTAQLLASSFENFFKNFKKESKILSEETIALIESHLENKNLPGAVSAISDALRNVDRAPLNIAVTGETGAGKSSFINALKGVWDEKEGAAPTGVTETTMKRTPYTHPKLPTVTIWDLPGIGSTSFPLQNYLTEMKFAEYDFFVIISATRFKDTDAHLAKAIAKMNTKFYFVRTKIDHDLDNERRSKSKTFNRHSVLKKIRDDYSKHLKEALSSEPRIFLVSNFDVSDFDFPELETTLLGELPAHKRHIFMLSLHSVTESAIDRKRDFLKQKIWLEALKAGAWATIPLGGLVRDKIQKVEETLDLYRSYFGLDDASLENIAKDFNVSVNEIKAHLKSFHLLTRAKDMSLEEKLLKYIEYISSVTGGPLATGLYFRKTFYLKSLFIDTVSSDAKTLLNKEEFLSKKVGSCMSDDTEYWEALTEP", "length": 842, "header": "tr|A0A9J7H689-1|A0A9J7H689_CRIGR Isoform 1 of Uncharacterized protein LOC100768826 OS=Cricetulus griseus OX=10029 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annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 4% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"MGSGRVPGFCLLVLLVHARAAQHGKAAQDVDECVEGTDHCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFRLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRPEEGTNCMNKNHGCAHICRETPKGGTACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHVKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCSCPVGFMLQPDRKTCKDIDECRLNNGGCDHMCRNTVGSFECSCKKGYKLLINERSCQDIDECSFDRTCDHMCVNTPGSFQCLCHRGYLLYGVTHCGDVDECSSNKGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPVKCQSNPGASKAMLSCNRSGKKDTCALTCPSRARFLPESENGFTVSCGTPSPKAAAARGIHPGNGTTSNQCHEAAVLSVKQRASFKIKDAKCRLHLRNKGKVEEASRMAGPGGASCSDCQVTFIHLKCDSSRKGKGRRARTPGKEVTRLTLELEAEVRAEETTAGCGLPCLRQRMERRLKGSLKMLRKSINQDRFLLRLAGLDYELAHKPGQVAGDRAELTEVCRPGQHRAGTKCVSCPQGTYYHGQTEQCVPCPAGTFQEREGQLSCDLCPGSDAHGPLGATNVTTCAGQCPPGQHSVDGFKPCQPCPRGTYQPEAGRTLCFPCGGGLTTKHEGAVSFQDCDTKVQCSPGHYYNTSTHRCIRCPMGSYQPHFRQNFCTRCPGNTSTDFDGSTSVAQCKNRQCGGELGEFTGYIESPNYPGNYPAGVECVWNINPPPKRKILIVVPEIFLPSEDECGDVLVMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYVTYDEDYEQLVEDIVRDGRLYASENHQEILKDKKLIKAFFEVLAHPQNYFKYTEKHKEMLPKSFIKLLRSKVSSFLRPYK", "length": 992, "header": "tr|A0A9J7H6B9-1|A0A9J7H6B9_CRIGR Isoform 1 of Signal peptide, CUB and EGF-like domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=Scube3 PE=4 SV=1 CANONICAL=A0A9J7H6B9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H6B9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6B9/entry#A0A9J7H6B9-1", "sequence": { "sequence": "MGSGRVPGFCLLVLLVHARAAQHGKAAQDVDECVEGTDHCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFRLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRPEEGTNCMNKNHGCAHICRETPKGGTACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHVKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCSCPVGFMLQPDRKTCKDIDECRLNNGGCDHMCRNTVGSFECSCKKGYKLLINERSCQDIDECSFDRTCDHMCVNTPGSFQCLCHRGYLLYGVTHCGDVDECSSNKGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPVKCQSNPGASKAMLSCNRSGKKDTCALTCPSRARFLPESENGFTVSCGTPSPKAAAARGIHPGNGTTSNQCHEAAVLSVKQRASFKIKDAKCRLHLRNKGKVEEASRMAGPGGASCSDCQVTFIHLKCDSSRKGKGRRARTPGKEVTRLTLELEAEVRAEETTAGCGLPCLRQRMERRLKGSLKMLRKSINQDRFLLRLAGLDYELAHKPGQVAGDRAELTEVCRPGQHRAGTKCVSCPQGTYYHGQTEQCVPCPAGTFQEREGQLSCDLCPGSDAHGPLGATNVTTCAGQCPPGQHSVDGFKPCQPCPRGTYQPEAGRTLCFPCGGGLTTKHEGAVSFQDCDTKVQCSPGHYYNTSTHRCIRCPMGSYQPHFRQNFCTRCPGNTSTDFDGSTSVAQCKNRQCGGELGEFTGYIESPNYPGNYPAGVECVWNINPPPKRKILIVVPEIFLPSEDECGDVLVMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYVTYDEDYEQLVEDIVRDGRLYASENHQEILKDKKLIKAFFEVLAHPQNYFKYTEKHKEMLPKSFIKLLRSKVSSFLRPYK", "length": 992, "header": "tr|A0A9J7H6B9-1|A0A9J7H6B9_CRIGR Isoform 1 of Signal peptide, CUB and EGF-like domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=Scube3 PE=4 SV=1 CANONICAL=A0A9J7H6B9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6B9/entry#A0A9J7HAD3-1", "sequence": { "sequence": "MGSGRVPGFCLLVLLVHARAAQHGKAAQDVDECVEGTDHCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFRLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRPEGTNCMNKNHGCAHICRETPKGGTACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHVKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCSCPVGFMLQPDRKTCKDIDECRLNNGGCDHMCRNTVGSFECSCKKGYKLLINERSCQDIDECSFDRTCDHMCVNTPGSFQCLCHRGYLLYGVTHCGDVDECSSNKGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPVKCQSNPGASKAMLSCNRSGKKDTCALTCPSRARFLPESENGFTVSCGTPSPKAAAARGIHPGNGTTSNQCHEAAVLSVKQRASFKIKDAKCRLHLRNKGKVEEASRMAGPGGASCSDCQVTFIHLKCDSSRKGKGRRARTPGKEVTRLTLELEAEVRAEETTAGCGLPCLRQRMERRLKGSLKMLRKSINQDRFLLRLAGLDYELAHKPGQVAGDRAELTEVCRPGQHRAGTKCVSCPQGTYYHGQTEQCVPCPAGTFQEREGQLSCDLCPGSDAHGPLGATNVTTCAGQCPPGQHSVDGFKPCQPCPRGTYQPEAGRTLCFPCGGGLTTKHEGAVSFQDCDTKVQCSPGHYYNTSTHRCIRCPMGSYQPHFRQNFCTRCPGNTSTDFDGSTSVAQCKNRQCGGELGEFTGYIESPNYPGNYPAGVECVWNINPPPKRKILIVVPEIFLPSEDECGDVLVMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYVTYDEDYEQLVEDIVRDGRLYASENHQEILKDKKLIKAFFEVLAHPQNYFKYTEKHKEMLPKSFIKLLRSKVSSFLRPYK", "length": 991, "header": "tr|A0A9J7HAD3-1|A0A9J7HAD3_CRIGR Computationally mapped isoform of Signal peptide, CUB and EGF-like domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=Scube3 PE=4 SV=1 CANONICAL=A0A9J7H6B9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6B9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6B9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6B9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6B9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758001", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758001", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of smoothened signaling pathway", "id": "GO:0045880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045880", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6B9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6B9" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6B9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6B9" } ], "pmid": "" }, { "name": "positive regulation of osteoblast differentiation", "id": "GO:0045669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045669", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6B9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6B9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6B9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6B9" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6B9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6B9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6B9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6B9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 684, "end_pos": 686, "annotation": "n_glycosylation_sequon" }, { "start_pos": 755, "end_pos": 757, "annotation": "n_glycosylation_sequon" }, { "start_pos": 784, "end_pos": 786, "annotation": "n_glycosylation_sequon" }, { "start_pos": 865, "end_pos": 867, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H6B9", "database": "UniProtKB", "url": 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"phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 417, "end_pos": 419 }, { "start_pos": 464, "end_pos": 466 }, { "start_pos": 684, "end_pos": 686 }, { "start_pos": 755, "end_pos": 757 }, { "start_pos": 784, "end_pos": 786 }, { "start_pos": 865, "end_pos": 867 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H6C0-1", "uniprot_ac": "A0A9J7H6C0", "uniprot_id": "A0A9J7H6C0_CRIGR", "mass": { "chemical_mass": 15933.0, "monoisotopic_mass": 15933.0 }, "refseq": { "ac": "XP_035303346", "name": "60S ribosomal protein L27a-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303346" }, "gene_names": [ { "name": "LOC113836823", "type": "recommended", "evidence": [ { "id": "A0A9J7H6C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C0" } ] }, { "name": "LOC113836823", "type": "synonym", "evidence": [ { "id": "XP_035303346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303346" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein uL15", "type": "recommended", "evidence": [ { "id": "A0A9J7H6C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C0/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L27a-like", "type": "synonym", "evidence": [ { "id": "XP_035303346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303346" } ] }, { "name": "60S ribosomal protein L27a", "type": "synonym", "evidence": [ { "id": "A0A9J7H6C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303346", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303346" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6C0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113836823", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C0", "locus": {} } ], "crossref": [ { "id": "A0A9J7H6C0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H6C0", "database": "AlphaFoldDB", "categories": [] }, { "id": "113836823", "url": "https://www.ncbi.nlm.nih.gov/gene/113836823", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113836823", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113836823", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H6C0", "url": "https://www.orthodb.org/?gene=A0A9J7H6C0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11721", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11721", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11721:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11721:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00828", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00828", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303346", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303346", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H6C0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSRLRKTRKLRGHMSHGHGRIGKHHKHPGGLGNAGGMHHHRINFDKYHPGYFGKGGMRHYHLKRNQSFCPTVNLDKLWTLVSEQTRVNAAKNKTGAVPIIDVRSGYYKVPGKGKLPKQPVIVKAKFFSRRAEEKIKGVGGA", "length": 142, "header": "tr|A0A9J7H6C0-1|A0A9J7H6C0_CRIGR Isoform 1 of Large ribosomal subunit protein uL15 OS=Cricetulus griseus OX=10029 GN=LOC113836823 PE=3 SV=1 CANONICAL=A0A9J7H6C0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H6C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C0/entry#A0A9J7H6C0-1", "sequence": { "sequence": "MPSRLRKTRKLRGHMSHGHGRIGKHHKHPGGLGNAGGMHHHRINFDKYHPGYFGKGGMRHYHLKRNQSFCPTVNLDKLWTLVSEQTRVNAAKNKTGAVPIIDVRSGYYKVPGKGKLPKQPVIVKAKFFSRRAEEKIKGVGGA", "length": 142, "header": "tr|A0A9J7H6C0-1|A0A9J7H6C0_CRIGR Isoform 1 of Large ribosomal subunit protein uL15 OS=Cricetulus griseus OX=10029 GN=LOC113836823 PE=3 SV=1 CANONICAL=A0A9J7H6C0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6C0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6C0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H6C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C0" }, { "id": "PF00828", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00828" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein uL15/eL18", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 141, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 66, "end_pos": 68 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303989" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dock2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C1", "locus": {} } ], "crossref": [ { "id": "cd11706", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11706", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766266", "url": "https://www.ncbi.nlm.nih.gov/gene/100766266", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046769", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046769", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046770", "url": 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16172", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16172", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23554", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23554", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303989", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H6C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1859, "header": "tr|A0A9J7H6C1-1|A0A9J7H6C1_CRIGR Isoform 1 of Dedicator of cytokinesis protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dock2 PE=3 SV=1 CANONICAL=A0A9J7H6C1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1687, "start_aa": "Thr", "end_pos": 1687, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1687", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766266", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766266", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C1" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C1" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": 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"date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H6C4-1", "uniprot_ac": "A0A9J7H6C4", "uniprot_id": "A0A9J7H6C4_CRIGR", "mass": { "chemical_mass": 19529.0, "monoisotopic_mass": 19529.0 }, "refseq": { "ac": "XP_035305686", "name": "60S ribosomal protein L19-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305686" }, "gene_names": [ { "name": "LOC103159764", "type": "recommended", "evidence": [ { "id": "A0A9J7H6C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C4" } ] }, { "name": "LOC103159764", "type": "synonym", "evidence": [ { "id": "XP_035305686", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305686" } ] } ], "protein_names": [ { "name": "Ribosomal protein L19", "type": "recommended", "evidence": [ { "id": "A0A9J7H6C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6C4/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L19-like isoform 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6K4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6K4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768629", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768629", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6K4" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304857", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304857" } ] }, { "annotation": "Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. Plays a role in the assembly of the gamma-tubulin ring complex (gTuRC), which regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments. Part of the ACTR1A/ACTB filament around which the dynactin complex is built. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6L7#function" }, { "database": "UniProtKB", "id": "ARBA00093387", "url": "https://www.uniprot.org/uniprotkb/ARBA00093387#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6L7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Actg2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6L7", "locus": {} } ], "crossref": [ { "id": "A0A9J7H6L7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H6L7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768744", "url": "https://www.ncbi.nlm.nih.gov/gene/100768744", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768744", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768744", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H6L7", "url": "https://www.orthodb.org/?gene=A0A9J7H6L7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11937", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11937", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304857", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304857", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H6L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6L7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPVLPDKWLTILFSSHPKVLQALAHSATSTMCEEETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVHRKCF", "length": 407, "header": "tr|A0A9J7H6L7-1|A0A9J7H6L7_CRIGR Isoform 1 of Actin, cytoplasmic 1 OS=Cricetulus griseus OX=10029 GN=Actg2 PE=3 SV=1 CANONICAL=A0A9J7H6L7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H6L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6L7/entry#A0A9J7H6L7-1", "sequence": { "sequence": "MSPVLPDKWLTILFSSHPKVLQALAHSATSTMCEEETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVHRKCF", "length": 407, "header": "tr|A0A9J7H6L7-1|A0A9J7H6L7_CRIGR Isoform 1 of Actin, cytoplasmic 1 OS=Cricetulus griseus OX=10029 GN=Actg2 PE=3 SV=1 CANONICAL=A0A9J7H6L7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6L7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6L7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768744", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768744", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6L7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6L7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 44, "end_pos": 46 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H6M3-1", "uniprot_ac": "A0A9J7H6M3", "uniprot_id": "A0A9J7H6M3_CRIGR", "mass": { "chemical_mass": 56802.0, "monoisotopic_mass": 56802.0 }, "refseq": { "ac": "XP_035303987", "name": "rhomboid-related protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303987" }, "gene_names": [ { "name": "Rhbdl1", "type": "recommended", "evidence": [ { "id": "A0A9J7H6M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6M3" } ] }, { "name": "Rhbdl1", "type": "synonym", "evidence": [ { "id": "XP_035303987", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303987" } ] } ], "protein_names": [ { "name": "Rhomboid-related protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7H6M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6M3/entry#names_and_taxonomy" } ] }, { "name": "3.4.21.105", "type": "synonym", "evidence": [ { "id": "A0A9J7H6M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6M3/entry#names_and_taxonomy" } ] }, { "name": "Rhomboid-like protein 1", "type": "synonym", "evidence": [ { "id": "A0A9J7H6M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6M3/entry#names_and_taxonomy" } ] }, { "name": "rhomboid-related protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035303987", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303987" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 20% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303987", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303987" } ] }, { "annotation": "May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6M3#function" }, { "database": "UniProtKB", "id": "ARBA00057065", "url": "https://www.uniprot.org/uniprotkb/ARBA00057065#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6M3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rhbdl1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6M3", "locus": {} } ], "crossref": [ { "id": "A0A9J7H6M3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H6M3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100771192", "url": "https://www.ncbi.nlm.nih.gov/gene/100771192", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022764", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022764", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771192", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771192", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H6M3", "url": "https://www.orthodb.org/?gene=A0A9J7H6M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45840", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45840", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45840:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45840:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01694", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01694", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303987", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303987", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H6M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6M3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSCGSGSSCLVGDRSAQDVRESRRRVRVLGTRVLCPCTRRAGISVTLSELGAHRAEQVERAGRGGAERSAEQPLPASADPGPRPGSMDRSSLLQLIQEQGEYEVLEQPNQASCPARAWEQAGSSKQALTGPEVQLPSQPGSALWLEVGPPSTPPPQQLDPENTGFIGADTFAGLVHSHELPLDPTKLDMLVALAQSNERGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGLLDEPGLGIYKRFVRYVAYEILPCEVDRRWYFYRHRSCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAIFWNVFAYDLLGADIPPPP", "length": 517, "header": "tr|A0A9J7H6M3-1|A0A9J7H6M3_CRIGR Isoform 1 of Rhomboid-related protein 1 OS=Cricetulus griseus OX=10029 GN=Rhbdl1 PE=3 SV=1 CANONICAL=A0A9J7H6M3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H6M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6M3/entry#A0A9J7H6M3-1", "sequence": { "sequence": "MPSCGSGSSCLVGDRSAQDVRESRRRVRVLGTRVLCPCTRRAGISVTLSELGAHRAEQVERAGRGGAERSAEQPLPASADPGPRPGSMDRSSLLQLIQEQGEYEVLEQPNQASCPARAWEQAGSSKQALTGPEVQLPSQPGSALWLEVGPPSTPPPQQLDPENTGFIGADTFAGLVHSHELPLDPTKLDMLVALAQSNERGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGLLDEPGLGIYKRFVRYVAYEILPCEVDRRWYFYRHRSCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAIFWNVFAYDLLGADIPPPP", "length": 517, "header": "tr|A0A9J7H6M3-1|A0A9J7H6M3_CRIGR Isoform 1 of Rhomboid-related protein 1 OS=Cricetulus griseus OX=10029 GN=Rhbdl1 PE=3 SV=1 CANONICAL=A0A9J7H6M3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 153, "start_aa": "Thr", "end_pos": 153, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr153", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"monoisotopic_mass": 78240.0 }, "refseq": { "ac": "XP_035304181", "name": "ras guanyl-releasing protein 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304181" }, "gene_names": [ { "name": "Rasgrp3", "type": "recommended", "evidence": [ { "id": "A0A9J7H6P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P0" } ] }, { "name": "Rasgrp3", "type": "synonym", "evidence": [ { "id": "XP_035304181", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304181" } ] } ], "protein_names": [ { "name": "Ras guanyl-releasing protein 3 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H6P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P0/entry#names_and_taxonomy" } ] }, { "name": "ras guanyl-releasing protein 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035304181", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304181" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304181", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304181" } ] }, { "annotation": "Functions as a calcium- and diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. Activates the Erk/MAP kinase cascade. Regulates T-cell/B-cell development, homeostasis and differentiation by coupling T-lymphocyte/B-lymphocyte antigen receptors to Ras. Regulates NK cell cytotoxicity and ITAM-dependent cytokine production by activation of Ras-mediated ERK and JNK pathways. Functions in mast cell degranulation and cytokine secretion, regulating FcERI-evoked allergic responses. May also function in differentiation of other cell types. Proto-oncogene, which promotes T-cell lymphomagenesis when its expression is deregulated.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6P0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P0#function" }, { "database": "UniProtKB", "id": "ARBA00056571", "url": "https://www.uniprot.org/uniprotkb/ARBA00056571#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6P0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rasgrp3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P0", "locus": {} } ], "crossref": [ { "id": "A0A9J7H6P0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H6P0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00051", "url": 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304181", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304181", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H6P0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSSGLGKAATLDELLNTCIEMFDDNGELNDSYLPRIVLLMHRWYLSSTELAEKLLCMYQNTSGEGCDEFRLKVCYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHINLMDISSIPSYDWMRRVTQRKKASKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYVIHGCLENNPTLERSIALFNGISKWVQLMVLSKPSPQQRAEVITKFINVAQKLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCEGFKIPILGVHLKDLIAVHVIFPDWLEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLLTLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWASGVIPKPDPTIINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMNYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRLARAPSLGSNPGSLPGSPALPPVQDEVFEFPGVAAGHRDLDSRAITLVTGSSRKISVRLQRATTSQATQTEPVWSEADWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPMVQGGVDVVDRGTAFEPDQDEGQDEAKQDGEDG", "length": 691, "header": "tr|A0A9J7H6P0-1|A0A9J7H6P0_CRIGR Isoform 1 of Ras guanyl-releasing protein 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Rasgrp3 PE=3 SV=1 CANONICAL=A0A9J7H6P0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H6P0-1", "url": 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"glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305204", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305204" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6P1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P1#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H795", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H795" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100763909", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR050636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763909", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763909", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H6P1", "url": "https://www.orthodb.org/?gene=A0A9J7H6P1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H795", "url": "https://www.orthodb.org/?gene=A0A9J7H795", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24376", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24376", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24376:SF189", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24376:SF189", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H795", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H795", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H795-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H795-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYHQEDDTNSDMTSDDDMSRTGRETPPPRSSHSFSSDRDQERRGRSREVEPRDRWPYNRNPRSRLPQRDLSLPVMSRSHFGLERDDDRRSLDYESRSQDAESYQNIVDRNEDKSPQNPIQDNLENYRKLLSLGVQLAEDDRHSHMTQGHSSRSKRSAYPSTSRGLKPMPEGKKPAHRRGICEEESSHGVIMEKFIKDVSRSSKSGRAREPNERPPPRFPRPSDNWKDSSSTKRESVIQERAPEAGTFRGAFRVNTELLSRSRALERKRRYHFESDDKGHESKSCVRKKPFECGSEMRQAMSMGNVNSAPSTDAQPIDPLGADPYVCDECGRSFGVISEFVEHQIMHTRENLYEYGESFIHSVAVNEVQKGQGGGKRFECKECGETFRRSAALAEHRQTHAREYLAEGRDQDDEDAVMPSPTFSELQKMYGKDKFYECKVCKETFLHSSALIEHQKTHGRGNPGDDERQRERERMRARAREQREQREREREREREREREREPFLTCPNFNEFHNMYRKEKFYECKVCGESFLHLSSLREHQKIHTRGNPFENKNRACEETFVPSQALKRRQKTYREKLFEFNNARDALMDGAGPGDHHKNRPRKSFFEGRAFEKPFTESHKSHTITRPPENKDEDKPFTISANPNDKPKPPAAEGGSQGKPFQRSVIRGALGFTKPKPVAESSTQTSGVFTHPRALSAASAYDGKDYKGSLIHSLPVPRALKRHRASGQGECSSDDGEPSIYMPDLTSKRRKIPGAGEDAYTGSSSLGLGLGLGRRDPILPIVPRAEPPTLSAESRDSSQDVTFSVPSSSVREHQKARAKKKYMEPRSNETSVIHSLGPFGDLQAIRRRPKIFECQECGEAFARRSELIEHQKIHDREGPSGSRLFERSVIRGRSRSLVPGDPQTSYAQERFVQEQVRKFRAFAQRSATSNSLGVQKIYNQEKYYAEEPHGKDTLGHKSHDTEPQGQKPHGDEPQDQEMRSSEEARGDQPHGQEPHGDEPQDQEPQDQEMRNSSDEPRGDEPHGQQSPRQAPASGSNEHERHRHDDVGDTIYECQDCGLGFADLSDLTSHQDVHSRKSLVDSREYAHSEVHAHSLGEFEKKFSGEKLYECPKCGESFTHSSLLFEHQRIHEQDQLHSSSAKTSDDGLVALMPARPRRNRGNEASTAAVSGSAIRCRQCGQGFIHSSALNEHMRQHRDEEAAAMEQGELAEDMFIQGLALTEYQGSETEEKLFECTVCGECFFTAKQLGDHHTKVHKDEPYEYGPSYTHASFLTEPLRKRMPLYECKDCGQPFLDDTVIDERMVFHRQREREQERDRDGSDIVAAPAARDGEANALVPQEALRIQGSNAEMAEPEVEAAEPEVEAAEPEVEAAEPDGEAEGPEGEAAEPDGEAEQPNGEAEQPNGEADEPDGAGIEDPEERAVAAAAAASDDDDEPEDEVEEPEGDADEPDVADLEDPEEEGEDQEIEVEEPYYNCHECTETFATSAAFGEHLKSHASVIIFEPANAPGECSGYIEHASTSAGGAEQADDKYFKCDVCGQLFHDRLSLARHQNSHTG", 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Computationally mapped isoform of Paternally-expressed gene 3 protein OS=Cricetulus griseus OX=10029 GN=LOC100763909 PE=3 SV=1 CANONICAL=A0A9J7H795-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H795-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H795/entry#A0A9J7H795-1", "sequence": { "sequence": "MYHQEDDTNSDMTSDDDMSRTGRETPPPRSSHSFSSDRDQERRGRSREVEPRDRWPYNRNPRSRLPQRDLSLPVMSRSHFGLERDDDRRSLDYESRSQDAESYQNIVDRNEDKSPQNPIQDNLENYRKLLSLGVQLAEDDRHSHMTQGHSSRSKRSAYPSTSRGLKPMPEGKKPAHRRGICEEESSHGVIMEKFIKDVSRSSKSGRAREPNERPPPRFPRPSDNWKDSSSTKRESVIQERAPEAGTFRGAFRVNTELLSRSRALERKRRYHFESDDKGHESKSCVRKKPFECGSEMRQAMSMGNVNSAPSTDAQPIDPLGADPYVCDECGRSFGVISEFVEHQIMHTRENLYEYGESFIHSVAVNEVQKGQGGGKRFECKECGETFRRSAALAEHRQTHAREYLAEGRDQDDEDAVMPSPTFSELQKMYGKDKFYECKVCKETFLHSSALIEHQKTHGRGNPGDDERQRERERMRARAREQREQREREREREREREREREPFLTCPNFNEFHNMYRKEKFYECKVCGESFLHLSSLREHQKIHTRGNPFENKNRACEETFVPSQALKRRQKTYREKLFEFNNARDALMDGAGPGDHHKNRPRKSFFEGRAFEKPFTESHKSHTITRPPENKDEDKPFTISANPNDKPKPPAAEGGSQGKPFQRSVIRGALGFTKPKPVAESSTQTSGVFTHPRALSAASAYDGKDYKGSLIHSLPVPRALKRHRASGQGECSSDDGEPSIYMPDLTSKRRKIPGAGEDAYTGSSSLGLGLGLGRRDPILPIVPRAEPPTLSAESRDSSQDVTFSVPSSSVREHQKARAKKKYMEPRSNETSVIHSLGPFGDLQAIRRRPKIFECQECGEAFARRSELIEHQKIHDREGPSGSRLFERSVIRGRSRSLVPGDPQTSYAQERFVQEQVRKFRAFAQRSATSNSLGVQKIYNQEKYYAEEPHGKDTLGHKSHDTEPQGQKPHGDEPQDQEMRSSEEARGDQPHGQEPHGDEPQDQEPQDQEMRNSSDEPRGDEPHGQQSPRQAPASGSNEHERHRHDDVGDTIYECQDCGLGFADLSDLTSHQDVHSRKSLVDSREYAHSEVHAHSLGEFEKKFSGEKLYECPKCGESFTHSSLLFEHQRIHEQDQLHSSSAKTSDDGLVALMPARPRRNRGNEASTAAVSGSAIRCRQCGQGFIHSSALNEHMRQHRDEEAAAMEQGELAEDMFIQGLALTEYQGSETEEKLFECTVCGECFFTAKQLGDHHTKVHKDEPYEYGPSYTHASFLTEPLRKRMPLYECKDCGQPFLDDTVIDERMVFHRQREREQERDRDGSDIVAAPAARDGEANALVPQEALRIQGSNAEMAEPEVEAAEPEVEAAEPEVEAAEPDGEAEGPEGEAAEPDGEAEQPNGEAEQPNGEADEPDGAGIEDPEERAVAAAAAASDDDDEPEDEVEEPEGDADEPDVADLEDPEEEGEDQEIEVEEPYYNCHECTETFATSAAFGEHLKSHASVIIFEPANAPGECSGYIEHASTSAGGAEQADDKYFKCDVCGQLFHDRLSLARHQNSHTG", "length": 1555, "header": "tr|A0A9J7H795-1|A0A9J7H795_CRIGR Isoform 1 of Paternally-expressed gene 3 protein OS=Cricetulus griseus OX=10029 GN=LOC100763909 PE=3 SV=1 CANONICAL=A0A9J7H795-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6P1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6P1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6P1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763909", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763909", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H795", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H795" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H795", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H795" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H795", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H795" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H795", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H795" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H795", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H795" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": 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"length": 1683, "header": "tr|A0A9J7H6Q3-1|A0A9J7H6Q3_CRIGR Isoform 1 of Collagen alpha-1(XXIV) chain OS=Cricetulus griseus OX=10029 GN=LOC103158657 PE=4 SV=1 CANONICAL=A0A9J7H6Q3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1003, "start_aa": "Thr", "end_pos": 1003, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1003", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1412, "start_aa": "Thr", "end_pos": 1412, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1412", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103158657", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103158657", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q3" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1481, "end_pos": 1483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1547, "end_pos": 1549, "annotation": "n_glycosylation_sequon" }, { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" 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"date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H6Q9-1", "uniprot_ac": "A0A9J7H6Q9", "uniprot_id": "A0A9J7H6Q9_CRIGR", "mass": { "chemical_mass": 49538.0, "monoisotopic_mass": 49538.0 }, "refseq": { "ac": "XP_035304049", "name": "protein Wnt-9b isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304049" }, "gene_names": [ { "name": "Wnt9b", "type": "recommended", "evidence": [ { "id": "A0A9J7H6Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9" } ] }, { "name": "Wnt9b", "type": "synonym", "evidence": [ { "id": "XP_035304049", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304049" } ] } ], "protein_names": [ { "name": "Protein Wnt", "type": "recommended", "evidence": [ { "id": "A0A9J7H6Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9/entry#names_and_taxonomy" } ] }, { "name": "protein Wnt-9b isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035304049", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304049" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 28% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304049", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304049" } ] }, { "annotation": "Ligand for members of the frizzled family of seven transmembrane receptors.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Q9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9#function" }, { "database": "UniProtKB", "id": "RU003500", "url": "https://www.uniprot.org/uniprotkb/RU003500#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Q9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Wnt9b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9", "locus": {} } ], "crossref": [ { "id": "A0A9J7H6Q9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H6Q9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19354", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19354", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766088", "url": "https://www.ncbi.nlm.nih.gov/gene/100766088", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005817", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005817", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766088", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766088", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H6Q9", "url": "https://www.orthodb.org/?gene=A0A9J7H6Q9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12027:SF84", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12027:SF84", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00110", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00110", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304049", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304049", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H6Q9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAQDTQDESTKGALTMQTALQRKPLSGASMGLCRAEAKAPGISGFPDPSSSLYLAWALICSTPGWAHLIDLESTGAPGTLPGPPPSNEASYFSGRQRGYGIQPNVLAEAGNSNGRDPKLTISLLILSSLTGRDVLTPFPGLGTAAAPAQAGAHLKQCDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRQERWNCSLEGRTGLLQRGFKETAFLYAVSAAALTHALARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGPKRGSKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRYDTAVKVSSATNEALGRLELWAPAKPGGPAKGLAPRPGDLVYMEDSPSFCRPSKYSPGTAGRVCSRDASCSSLCCGRGYDTQSRVVAFSCHCQVQWCCYVECQQCAQQELVYTCKR", "length": 460, "header": "tr|A0A9J7H6Q9-1|A0A9J7H6Q9_CRIGR Isoform 1 of Protein Wnt OS=Cricetulus griseus OX=10029 GN=Wnt9b PE=3 SV=1 CANONICAL=A0A9J7H6Q9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H6Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9/entry#A0A9J7H6Q9-1", "sequence": { "sequence": "MGAQDTQDESTKGALTMQTALQRKPLSGASMGLCRAEAKAPGISGFPDPSSSLYLAWALICSTPGWAHLIDLESTGAPGTLPGPPPSNEASYFSGRQRGYGIQPNVLAEAGNSNGRDPKLTISLLILSSLTGRDVLTPFPGLGTAAAPAQAGAHLKQCDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRQERWNCSLEGRTGLLQRGFKETAFLYAVSAAALTHALARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGPKRGSKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRYDTAVKVSSATNEALGRLELWAPAKPGGPAKGLAPRPGDLVYMEDSPSFCRPSKYSPGTAGRVCSRDASCSSLCCGRGYDTQSRVVAFSCHCQVQWCCYVECQQCAQQELVYTCKR", "length": 460, "header": "tr|A0A9J7H6Q9-1|A0A9J7H6Q9_CRIGR Isoform 1 of Protein Wnt OS=Cricetulus griseus OX=10029 GN=Wnt9b PE=3 SV=1 CANONICAL=A0A9J7H6Q9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Q9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Q9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766088", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766088", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "frizzled binding", "id": "GO:0005109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005109", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Q9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9" } ], "pmid": "" }, { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Q9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Q9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Q9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Q9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9" } ], "pmid": "" }, { "name": "regulation of epithelial cell differentiation", "id": "GO:0030856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030856", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Q9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9" } ], "pmid": "" }, { "name": "cell fate commitment", "id": "GO:0045165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6Q9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6Q9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H6R8-1", "uniprot_ac": "A0A9J7H6R8", "uniprot_id": "A0A9J7H6R8_CRIGR", "mass": { "chemical_mass": 272373.0, "monoisotopic_mass": 272373.0 }, "refseq": { "ac": "XP_035304064", "name": "glutamine-rich protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304064" }, "gene_names": [ { "name": "Qrich2", "type": "recommended", "evidence": [ { "id": "A0A9J7H6R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6R8" } ] }, { "name": "Qrich2", "type": "synonym", "evidence": [ { "id": "XP_035304064", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304064" } ] } ], "protein_names": [ { "name": "Glutamine-rich protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H6R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6R8/entry#names_and_taxonomy" } ] }, { "name": "glutamine-rich protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035304064", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304064" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 48% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304064", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304064" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6R8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Qrich2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6R8", "locus": {} } ], "crossref": [ { "id": "100761476", "url": "https://www.ncbi.nlm.nih.gov/gene/100761476", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032013", "database": "InterPro", "categories": [ "Protein Classification" ] 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"MPPSLVADRVTLRELADLAIGTPEVGAVNFTALHTLIVSMLKSLNLQEVLIDFQYPSVEPGRPTETIRSSFSVPHVPASKEKQEKRRSVFRLSVPQQSLENQVKDLGNLVQDLSKQIKTMDNKVQGLATQVDNISTDADIFQEFPRLEEDITLMGPQIPSTKPSRSYESTEVKERPEPTVGPPPRATQPRLSKTQKETVPAKSLNVLQELAEDVRTLREAQQKMHEVTELDQQELHQRVNELEKLVKDREDYLDQLNRKLNFAPGGEDITMVTWEELEQAITDGWKASRRVNKQGSWAVALCGIPESSSDSSTATFGRRKMTSSTSNDLQSGVFPKASAADQASGSISGSDQILAGGVGQSPERVTSGDQGRRSAGFRDPHSRAREQSQATSDGRGTREPAAPTGPRRNEQQLGPIQQDLSVARDQHDGFRTSQGRAYPRPDEHGIGRIGMDQPALLHPGPYPQTVIPLTTGQLGMLPPEMDDQGLVPLGVDQSGLLPPSVPDRGLQGLDKTSIGPITSVPLSASQQGMVLPRADQIGMEQAVMYDSGVGPWARDRQGLIPVAVDQHGFLVFGQAQQGLIPPGVDQQGLVLPAGIDQRVVPTSLPGQYSLASPRLMPVSTYQQVIGQPRLEAPGFAQPGTEQRGLIQPGAEAHGAVQAFVDEHGVVQRGVVQPGVDPRGLIQPGAEARGVVQPGVDQRGLIQPGAEARGAVQPGIDQRGLIQPGAEAHGAVQAFVDEHGVVQRGVVQPGVDPRGLIQPGAEVRGVVQPGVDQRGLIQPGAEARGAVQAFVDEHGVVQRGVVQPGVDQRGLIQPGAEARGAVQAFVDEHGVVQHGVVQPGVDQRGLIQPGAEARGVVQPGVDQRGLIQPGAEAHGVVQPGVDQRGLIQPGAEARGVVQPGVDQRGLIQPGAEARGAVQAFVDERGVVQRGVVQPGVDQRGLIQPGAEVRGVVQPGVDQRGLIQPGAEARGVVQPGVDQRGLIQPGAEARGVVQSGVDQRGLIQPGAEVRGVVQPGVDPRMLMRPATTDRRISEPAGSDRRSDEDRRSSEPVGAERRSLSQSGASWRGSARPGADRQSSIQPGADQSLAQPGTDQRGLVPPGTDWNGLVLPGTDQHLVPPGAGQPSLIQPGLAQLGAGQQGLVQPGTGQPVWVQPSTDQRGWVQPGTFVPGLVQPSVDQHDLVPLGMDHHGLAQPSAAQHGLVRPDVYAPGLMQPGAVQDSLVQPRMDQHGFVQPGANWNFAQSGVDQLGMAQPSAVQPDLVQPGVAQRVPMQPGVIPSSWVQPDPYSPRLIQPGIDQYGLVQPRTDQYGFVQPGAAQHGLLQPGRNQQGLLQPGIDQIDWAQPGMGQSGSVQPGAGESSLAQPGMNQQGLAQPSMDQRDWVQPGLARPGALPHGSAQLSADQQGLAQPRVYQSGPVQPGVDQRGPVQPGVDQRGLVQPGVDQRGPVQPGVDQRGPVQPGVDQRGPVQPGVDHRGRLQHGVDHRGRLQHGVDHRGRLQPGVDQRGPVPPGVYQHGLGQPGVDQHGPVQPGVDQQGPVQPGVYQRGPVQPGVDQRGPVQPGVDQRGPVQPGVYQRGPWQPGVDQRGPWQPGVDQRGPGQPGVDQRGLGSLVWISVAWGSLVWISVAWGSLVWISVAWGSLVWISVAWCSLVWISVAWCSLVWISVAWGSLVWISVAWCSLVWISVAWGSLVWISVAWCSLVWISVAWGSLVWISVAWCSLVWISVAWCSLVWISVAWCSLVWISVAWCSLVWISVAWCSLVQALKVWLSLVQVLKFELATPTGPDQDTTRTRPHASLSYLLQASSGSETQTDRQESLEKLAPNFPMAVETFRLLGEIISLYVELKEHMRKLEEEQTGLTDMEKIQNLLTTMVKKSIPQDLQEQLKSLKALNKEIRQDKAKLDRIQKLLDSDSTGGKDIKPSHLSLQLGILRVTVSDIEKELSDLRDSQERGKAAMENSVSEASLYLQDQLDKLRTIIENMLSSSSTLLSMSMTPHKFTGTTVPGQIDPEATCPACSLDVSHQVSLLVQRYEQLQDMVSSLAASRPSKKAKLQSQDEELLGHVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIEVLYQGIERLEKEKADREHLEMEIDVKADKSALASKVSRIQFDATTEQLNHMMQELVAKMSGQEQDWQKLLDKLLAEMDSKLDRLELDPVKQMLEDRWKSLRQQLKERSPLYQADEAAAMRRQLLAHFHCLSCDRPLETSVTGQVLSMTPMVPSMPGHRSIRPYTVFELEQVRQQSRSNLKLGGSLSRGDLSQMERSVGRLRSMHSKMLMDIEKVQIHFGGSVKASSQMIRELLHAQCLSHPCYKRGLETADYTYSTVPRRCGGSHTLTYPYRRNRPQHLSPLEEIQIAMKHDEVDILGLDGHIYKGRMDTRLPGILAKDASGMPKSKSRQLQQLQQLQQLQQLQQLQQGQHGRPHNHRQPSLGLPPFRPLSAQMLTDSNAEMAGLQGSPSGLKVHMEVSPREEMEEPTRGPRSTAAH", "length": 2509, "header": "tr|A0A9J7H6R8-1|A0A9J7H6R8_CRIGR Isoform 1 of Glutamine-rich protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Qrich2 PE=4 SV=1 CANONICAL=A0A9J7H6R8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 179, "start_aa": "Thr", "end_pos": 179, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr179", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 404, "start_aa": "Thr", "end_pos": 404, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr404", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6R8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6R8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761476", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761476", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6R8" } ], "pmid": "" }, { "name": "cell projection assembly", "id": "GO:0030031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030031", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6R8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6R8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2074, "end_pos": 2076, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H6R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6R8" }, { "id": "PF16043", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16043" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4795", "eco_id": "ECO_0000259", "start_pos": 2049, "end_pos": 2255, "start_aa": "Gln", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 179, 404 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 }, { "start_pos": 2074, "end_pos": 2076 }, { "start_pos": 29, "end_pos": 31 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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}, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H7M8-1", "uniprot_ac": "A0A9J7H7M8", "uniprot_id": "A0A9J7H7M8_CRIGR", "mass": { "chemical_mass": 132332.0, "monoisotopic_mass": 132332.0 }, "refseq": { "ac": "XP_035296726", "name": "fibulin-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296726" }, "gene_names": [ { "name": "Fbln2", "type": "recommended", "evidence": [ { "id": "A0A9J7H7M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M8" } ] }, { "name": "Fbln2", "type": "synonym", "evidence": [ { "id": "XP_035296726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296726" } ] } ], "protein_names": [ { "name": "Fibulin-2", "type": "recommended", "evidence": [ { "id": "A0A9J7H7M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M8/entry#names_and_taxonomy" } ] }, { "name": "fibulin-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035296726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296726" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613584.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035296726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296726" } ] }, { "annotation": "Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6T5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T5#function" }, { "database": "UniProtKB", "id": "ARBA00053524", "url": "https://www.uniprot.org/uniprotkb/ARBA00053524#function" }, { "database": "UniProtKB", "id": "A0A9J7H7M8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7M8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fbln2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M8", "locus": {} } ], "crossref": [ { "id": "A0A9J7H7M8", "url": 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"categories": [ "Protein Classification" ] }, { "id": "IPR055088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763343", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763343", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H7M8", "url": "https://www.orthodb.org/?gene=A0A9J7H7M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24034", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24034", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24034:SF158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24034:SF158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47333:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47333:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01821", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01821", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22914", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22914", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24532", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24532", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035296726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296726", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H6T5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7M8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMLLQESAGAWLALALITALTVSPGTAVPWQDCTGAECPPLENCIEEALEPGACCATCVQQGCACEGYQYYDCVQGGFVDGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPNCIEAVVVADSCPQCGQVGCVHNGHKYAAGHTFHLSPCRACHCPDAGGELICYQLPGCHGNFSDAEEGDSERQYEDPYSYDQEVAEAETTMATVNEVQAGAEGPPAALGGGNLPPSSIRATPWPAALPRPTAAAALGPPASMQAKARRVTQEIDEEEEEEDEEEEEMEEMVVTEPPVAGDLGRLDSLPTTPPARPNLPVQEKEAEARAGPEENLIPDAQATPPSAGQEGAAPLSRSGPAGFIPSLATDSSPADPVKSSSHSTQSTLPPDRAQVSPSPEVPKEIPQRPQLRSQSRAEEDTDPNSVHSVPRGGPDVSTKDLIETCCAAGQQWAIDNDECQEIPQNGAESDVCRIAQRHCCVSYLKEKSCMAGVMGAKEGEACGAEDNDTCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPEATPRRVSEAEMANREALSLGTEAELPNSLPGDDQDECLLLPGELCQHLCINTVGSYRCACFPGFELQGDGRTCRPDGGAPQLDTARESAPRSESAQVSPNTIPLPVPQPNTCKDNGPCRQVCRVVGGTAMCSCFPGYAIMADGVSCEDQDECLMGTHDCSWKQFCVNTLGSFYCVNHTVLCAEGYILNAHRKCVDINECVTDLHTCTRDEHCVNTPGSFQCYKTLTCEPGYALTDGECTDVDECVTGTHNCQSGFSCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLLEPCRSGFSCINTVGSYTCQRNPLVCRRGYHANEDGSECVDVNECETGVHRCGEGQLCHNLPGSYRCDCKPGFQRDAFGRTCIDVNECWVSPGRLCQHTCENTPGSYRCSCAAGFILAADGKHCEDVNECEARRCSQECANIYGSYQCYCRQGYQLAEDGHSCTDIDECAQGAGILCTFRCVNVPGSYQCACPEQGYTMMANGRSCKDLDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVRVSETKCERTTCQDITECQTSPARITHYQLNFQTGLLVPAHIFRIGPAPAFAGDTISLTITKGNEEGYFVTSRLNAYTGVVSLQRSVLEPRDFALDVEMKLWRQGSVTTFLAKMYIFFTTFAP", "length": 1228, "header": "tr|A0A9J7H7M8-1|A0A9J7H7M8_CRIGR Isoform 1 of Fibulin-2 OS=Cricetulus griseus OX=10029 GN=Fbln2 PE=3 SV=1 CANONICAL=A0A9J7H7M8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H6T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M8/entry#A0A9J7H6T5-1", "sequence": { "sequence": 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"length": 1181, "header": "tr|A0A9J7H6T5-1|A0A9J7H7M8_CRIGR Computationally mapped isoform of Fibulin-2 OS=Cricetulus griseus OX=10029 GN=Fbln2 PE=3 SV=1 CANONICAL=A0A9J7H7M8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M8/entry#A0A9J7H7M8-1", "sequence": { "sequence": "MMLLQESAGAWLALALITALTVSPGTAVPWQDCTGAECPPLENCIEEALEPGACCATCVQQGCACEGYQYYDCVQGGFVDGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPNCIEAVVVADSCPQCGQVGCVHNGHKYAAGHTFHLSPCRACHCPDAGGELICYQLPGCHGNFSDAEEGDSERQYEDPYSYDQEVAEAETTMATVNEVQAGAEGPPAALGGGNLPPSSIRATPWPAALPRPTAAAALGPPASMQAKARRVTQEIDEEEEEEDEEEEEMEEMVVTEPPVAGDLGRLDSLPTTPPARPNLPVQEKEAEARAGPEENLIPDAQATPPSAGQEGAAPLSRSGPAGFIPSLATDSSPADPVKSSSHSTQSTLPPDRAQVSPSPEVPKEIPQRPQLRSQSRAEEDTDPNSVHSVPRGGPDVSTKDLIETCCAAGQQWAIDNDECQEIPQNGAESDVCRIAQRHCCVSYLKEKSCMAGVMGAKEGEACGAEDNDTCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPEATPRRVSEAEMANREALSLGTEAELPNSLPGDDQDECLLLPGELCQHLCINTVGSYRCACFPGFELQGDGRTCRPDGGAPQLDTARESAPRSESAQVSPNTIPLPVPQPNTCKDNGPCRQVCRVVGGTAMCSCFPGYAIMADGVSCEDQDECLMGTHDCSWKQFCVNTLGSFYCVNHTVLCAEGYILNAHRKCVDINECVTDLHTCTRDEHCVNTPGSFQCYKTLTCEPGYALTDGECTDVDECVTGTHNCQSGFSCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLLEPCRSGFSCINTVGSYTCQRNPLVCRRGYHANEDGSECVDVNECETGVHRCGEGQLCHNLPGSYRCDCKPGFQRDAFGRTCIDVNECWVSPGRLCQHTCENTPGSYRCSCAAGFILAADGKHCEDVNECEARRCSQECANIYGSYQCYCRQGYQLAEDGHSCTDIDECAQGAGILCTFRCVNVPGSYQCACPEQGYTMMANGRSCKDLDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVRVSETKCERTTCQDITECQTSPARITHYQLNFQTGLLVPAHIFRIGPAPAFAGDTISLTITKGNEEGYFVTSRLNAYTGVVSLQRSVLEPRDFALDVEMKLWRQGSVTTFLAKMYIFFTTFAP", "length": 1228, "header": "tr|A0A9J7H7M8-1|A0A9J7H7M8_CRIGR Isoform 1 of Fibulin-2 OS=Cricetulus griseus OX=10029 GN=Fbln2 PE=3 SV=1 CANONICAL=A0A9J7H7M8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6T5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6T5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763343", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763343", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7M8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M8" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7M8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7M8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7M8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1079, "end_pos": 1081, "annotation": "n_glycosylation_sequon" }, { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 744, 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"end_pos": 642, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1079, "end_pos": 1081 }, { "start_pos": 180, "end_pos": 182 }, { "start_pos": 504, "end_pos": 506 }, { "start_pos": 744, "end_pos": 746 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"gene_names": [ { "name": "LOC113832901", "type": "recommended", "evidence": [ { "id": "A0A9J7H6T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T8" } ] }, { "name": "LOC113832901", "type": "synonym", "evidence": [ { "id": "XP_035306631", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306631" } ] }, { "name": "LOC118239699", "type": "synonym", "evidence": [ { "id": "A0A9J7H6T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T8" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC113832901 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7H6T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC113832901 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035306631", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306631" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306631", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306631" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6T8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113832901", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T8", "locus": {} } ], "crossref": [ { "id": "A0A9J7H6T8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H6T8", "database": "AlphaFoldDB", "categories": [] }, { "id": "113832901", "url": "https://www.ncbi.nlm.nih.gov/gene/113832901", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050462", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050462", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:118239699", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239699", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HAS0", "url": "https://www.orthodb.org/?gene=A0A9J7HAS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18697", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18697", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306631", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306631", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H6T8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAS0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDY8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGHFPSLFGEGPRLEGFAIFTGDEEGGPPSSTLSQFLLSTLCRNRAAKVCSVLFGLCLVAVICALLSLETMGQTVTTPLSLTLSHWKDVQEYAHNQSVNVRKRKWITLCSSEWPTFDVGWPRDGTFNPQTIFQIKEKIMDPGPHGHPDQVAYIVTWEALVQDPPPWVRPFLHPKGPSLLPPSNRSNRPIPSAPTPPTPLIPPNPPSHSNLYPTVVKDTKAKEKKTPKVLPPGEDQLVDLLTEEPPPYPPLPPPPEAEADSAAALAEAAPDPSPMAYRLRGRREQPVPDSTTLPLRTGLNGQPQYWPFSASDLYNWKNNNPSFSADPVRLTSLIESVLTTHQPTWDDCQQLLQVLLTSEEKQRVLLEARKNVPGVNGQPTQLPNEIDAACPLERPEWDFTTEADTFSGWVEAFPTKHETAKIVTKKLLEEIFPRYGMPQVLGTDNGPAFVSQVSQSVATLLGIDWKLHCAYRPQSSGQVERMNRTIKETLTKLSLATGTRDWVLLLPLALYRARNTPGPHGLTPFEILYGVPTPIINFLDQDVSDFANSPSLQAHLQALQLVQREVWKPLAQAYKDQRDHPTIPHSYQIGDTVWVRRHQAKNLEPRWKGPYIVLLTTPTALKVDGIAAWIHASHVKPARPTDSATASEWTAHRTQNPLKIRLSRTPSC", "length": 668, "header": "tr|A0A9J7H6T8-1|A0A9J7H6T8_CRIGR Isoform 1 of Uncharacterized protein LOC113832901 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC113832901 PE=4 SV=1 CANONICAL=A0A9J7H6T8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H6T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T8/entry#A0A9J7H6T8-1", "sequence": { "sequence": "MTGHFPSLFGEGPRLEGFAIFTGDEEGGPPSSTLSQFLLSTLCRNRAAKVCSVLFGLCLVAVICALLSLETMGQTVTTPLSLTLSHWKDVQEYAHNQSVNVRKRKWITLCSSEWPTFDVGWPRDGTFNPQTIFQIKEKIMDPGPHGHPDQVAYIVTWEALVQDPPPWVRPFLHPKGPSLLPPSNRSNRPIPSAPTPPTPLIPPNPPSHSNLYPTVVKDTKAKEKKTPKVLPPGEDQLVDLLTEEPPPYPPLPPPPEAEADSAAALAEAAPDPSPMAYRLRGRREQPVPDSTTLPLRTGLNGQPQYWPFSASDLYNWKNNNPSFSADPVRLTSLIESVLTTHQPTWDDCQQLLQVLLTSEEKQRVLLEARKNVPGVNGQPTQLPNEIDAACPLERPEWDFTTEADTFSGWVEAFPTKHETAKIVTKKLLEEIFPRYGMPQVLGTDNGPAFVSQVSQSVATLLGIDWKLHCAYRPQSSGQVERMNRTIKETLTKLSLATGTRDWVLLLPLALYRARNTPGPHGLTPFEILYGVPTPIINFLDQDVSDFANSPSLQAHLQALQLVQREVWKPLAQAYKDQRDHPTIPHSYQIGDTVWVRRHQAKNLEPRWKGPYIVLLTTPTALKVDGIAAWIHASHVKPARPTDSATASEWTAHRTQNPLKIRLSRTPSC", "length": 668, "header": "tr|A0A9J7H6T8-1|A0A9J7H6T8_CRIGR Isoform 1 of Uncharacterized protein LOC113832901 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC113832901 PE=4 SV=1 CANONICAL=A0A9J7H6T8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T8/entry#A0A9J7HAS0-1", "sequence": { "sequence": "MTGHFPSLFGEGPRLEGFAIFTGDEEGGPPSSTLSQFLLSTLCRNRAAKVCSVLFGLCLVAVICALLSLETMGQTVTTPLSLTLSHWKDVQEYAHNQSVNVRKRKWITLCSSEWPTFDVGWPRDGTFNPQTIFQIKEKIMDPGPHGHPDQVAYIVTWEALVQDPPPWVRPFLHPKGPSLLPPSNRSNRPIPSAPTPPTPLIPPNPPSHSNLYPTVVKDTKAKEKKTPKVLPPGEDQLVDLLTEEPPPYPPLPPPPEAEADSAAALAEAAPDPSPMAYRLRGRREQPVPDSTTLPLRTGLNGQPQYWPFSASDLYNWKNNNPSFSADPVRLTSLIESVLTTHQPTWDDCQQLLQVLLTSEEKQRVLLEARKNVPGVNGQPTQLPNEIDAACPLERPEWDFTTEAAHLQALQLVQREVWKPLAQAYKDQRDHPTIPHSYQIGDTVWVRRHQAKNLEPRWKGPYIVLLTTPTALKVDGIAAWIHASHVKPARPTDSATASEWTAHRTQNPLKIRLSRTPSC", "length": 518, "header": "tr|A0A9J7HAS0-1|A0A9J7HAS0_CRIGR Computationally mapped isoform of Uncharacterized protein LOC113832901 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC113832901 PE=4 SV=1 CANONICAL=A0A9J7H6T8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KDY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T8/entry#A0A9J7KDY8-1", "sequence": { "sequence": "MTGHFPSLFGEGPRLEGFAIFTGDEEGGPPSSTLSQFLLSTLCRNRAAKVCSVLFGLCLVAVICALLSLETMGQTVTTPLSLTLSHWKDVQEYAHNQSVNVRKRKWITLCSSEWPTFDVGWPRDGTFNPQTIFQIKEKIMDPGPHGHPDQVAYIVTWEALVQDPPPWVRPFLHPKGPSLLPPSNRSNRPIPSAPTPPTPLIPPNPPSHSNLYPTVVKDTKAKEKKTPKVLPPGEDQLVDLLTEEPPPYPPLPPPPEAEADSAAALAEAAPDPSPMAYRLRGRREQPVPDSTTLPLRTGLNGQPQYWPFSASDLYNWKNNNPSFSADPVRLTSLIESVLTTHQPTWDDCQQLLQVLLTSEEKQRVLLEARKNVPGVNGQPTQLPNEIDAACPLERPEWDFTTEADTFSGWVEAFPTKHETAKIVTKKLLEEIFPRYGMPQVLGTDNGPAFVSQLIYRPSN", "length": 459, "header": "tr|A0A9J7KDY8-1|A0A9J7H6T8_CRIGR Computationally mapped isoform of Uncharacterized protein LOC113832901 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC113832901 PE=4 SV=1 CANONICAL=A0A9J7H6T8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 195, "start_aa": "Thr", "end_pos": 195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr195", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDY8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDY8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDY8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDY8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:118239699", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239699", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6T8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T8" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6T8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T8" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6T8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "virion assembly", "id": "GO:0019068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019068", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6T8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T8" } ], "pmid": "" }, { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6T8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H6T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6T8" }, { "id": "PS50994", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase catalytic", "eco_id": "ECO_0000259", "start_pos": 375, "end_pos": 532, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 195 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 }, { "start_pos": 483, "end_pos": 485 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H6V8-1", "uniprot_ac": "A0A9J7H6V8", "uniprot_id": "A0A9J7H6V8_CRIGR", "mass": { "chemical_mass": 37908.0, "monoisotopic_mass": 37908.0 }, "refseq": { "ac": "XP_035305465", "name": "serine/threonine-protein kinase SBK2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305465" }, "gene_names": [ { "name": "Sbk2", "type": "recommended", "evidence": [ { "id": "A0A9J7H6V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8" } ] }, { "name": "Sbk2", "type": "synonym", "evidence": [ { "id": "XP_035305465", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305465" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein kinase SBK2", "type": "recommended", "evidence": [ { "id": "A0A9J7H6V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A9J7H6V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8/entry#names_and_taxonomy" } ] }, { "name": "SH3 domain-binding kinase family member 2", "type": "synonym", "evidence": [ { "id": "A0A9J7H6V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein kinase SBK2", "type": "synonym", "evidence": [ { "id": "XP_035305465", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305465" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305465", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305465" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sbk2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8", "locus": {} } ], "crossref": [ { "id": "A0A9J7H6V8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H6V8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100768070", "url": "https://www.ncbi.nlm.nih.gov/gene/100768070", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768070", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768070", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H6V8", "url": "https://www.orthodb.org/?gene=A0A9J7H6V8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24359", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24359", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24359:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24359:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305465", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305465", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H6V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGKQSDDGSMDVAAVEDGGDEGLGGLTVEELQQGQETALALEDMMALSAQTLVRTEVDELYEEVRPLGQGRFGRVLLVTHRQKGTPLALKQLPKTSTSLRSFLYEFCVGLSLGTHPAIVAAYGIGIESASSYSFLTEPVLHGDLITFIQPKVGLPQPATQRCAAQLASALEHIHSHGLVYRDLKPENVLVCDPDCHRVKLTDFGHTRPRGTLLRLTGPPIPYTAPELCAPPPFPEGLPIQPALDAWALGVLIFCLLTGYFPWDQPLVEADAFFEDFIIWQASGQPQDRPQPWYGLSPVADALLWGLLDPQPRKRSPVSSIKGYLGQPWRQRGGEAEELAKELKEDG", "length": 347, "header": "tr|A0A9J7H6V8-1|A0A9J7H6V8_CRIGR Isoform 1 of Serine/threonine-protein kinase SBK2 OS=Cricetulus griseus OX=10029 GN=Sbk2 PE=3 SV=1 CANONICAL=A0A9J7H6V8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H6V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8/entry#A0A9J7H6V8-1", "sequence": { "sequence": "MPGKQSDDGSMDVAAVEDGGDEGLGGLTVEELQQGQETALALEDMMALSAQTLVRTEVDELYEEVRPLGQGRFGRVLLVTHRQKGTPLALKQLPKTSTSLRSFLYEFCVGLSLGTHPAIVAAYGIGIESASSYSFLTEPVLHGDLITFIQPKVGLPQPATQRCAAQLASALEHIHSHGLVYRDLKPENVLVCDPDCHRVKLTDFGHTRPRGTLLRLTGPPIPYTAPELCAPPPFPEGLPIQPALDAWALGVLIFCLLTGYFPWDQPLVEADAFFEDFIIWQASGQPQDRPQPWYGLSPVADALLWGLLDPQPRKRSPVSSIKGYLGQPWRQRGGEAEELAKELKEDG", "length": 347, "header": "tr|A0A9J7H6V8-1|A0A9J7H6V8_CRIGR Isoform 1 of Serine/threonine-protein kinase SBK2 OS=Cricetulus griseus OX=10029 GN=Sbk2 PE=3 SV=1 CANONICAL=A0A9J7H6V8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768070", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768070", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H6V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", "A0A8C2QND0-1", "G3HXQ8-1", "G3I724-1", "A0A8C2M0A2-1", "A0A9J7K2S5-1", "A0A8C2MMZ5-1", "A0A8C2QH69-1", "A0A8C2QL63-1", "A0A9J7K953-1", "A0A9J7G3C1-1", "A0A9J7GFS3-1", "A0A9J7JBH0-1", "A0A9J7FGD3-1", "A0A9J7FKM1-1", "A0A9J7JKJ1-1", "A0A9J7G180-1", "A0A9J7JTL3-1", "A0A9J7GQ42-1", "A0A9J7EZ53-1", "A0A9J7J5Z8-1", "A0A9J7EVK4-1", "A0A9J7F0G6-1", "A0A9J7FCC7-1", "A0A9J7K3S4-1", "A0A9J7GAF4-1", "A0A9J7GBF4-1", "A0A8C2MTI7-1", "A0A9J7J1N3-1", "A0A9J7F4P4-1", "A0A9J7JNU2-1", "A0A9J7FZY8-1", "A0A9J7H3M5-1", "A0A9J7JJV6-1", "A0A9J7GJE4-1", "A0A8C2LY52-1", "A0A9J7H8U3-1", "A0A9J7F821-1", "A0A8C2N185-1", "A0A9J7KFV8-1", "A0A8C2MQM0-1", "A0A8C2N310-1", "A0A9J7J6H1-1", "A0A9J7H2P9-1", "A0A9J7H4N5-1", "A0A3L7GPC7-1", "A0A9J7H6V8-1", "A0A3L7HV37-1", "A0A8C2LTZ7-1", "A0A9J7K7D8-1", "A0A8C2LDU9-1", "A0A8C2LTW4-1", "A0A9J7JAM4-1", "A0A9J7JXM2-1", "A0A9J7JRJ8-1", "A0A8C2QEB8-1", "A0A3L7HKC4-1", "A0A8C2LI14-1", "A0A8C2QDX9-1", "A0A9J7G1D9-1", "A0A9J7F985-1", "A0A8C2MCX3-1", "A0A8C2MEU5-1", "A0A8C2MFN1-1", "A0A8C2MMI4-1", "A0A9J7JAB2-1", "A0A9J7G969-1", "A0A8C2MQ42-1", "A0A8C2MR08-1", "A0A8C2MUQ5-1", "A0A9J7FZA7-1", "A0A8C2N3C9-1", "A0A8C2N6L4-1", "A0A8C2N9X1-1", "A0A8C2QHF9-1", "A0A8C2QI80-1", "A0A8C2QKP7-1", "A0A9J7F842-1", "A0A9J7FFS7-1", "A0A9J7FI14-1", "A0A9J7FJ23-1", "A0A9J7JLH7-1", "A0A9J7G270-1", "A0A8C2MH43-1", "A0A9J7FZ18-1", "A0A9J7G368-1", "A0A9J7G6S5-1", "A0A9J7K1H4-1", "A0A9J7H2T6-1", "A0A9J7H3N1-1", "A0A9J7H8L4-1", "A0A9J7JIW6-1", "A0A9J7JRI3-1", "A0A061I9F9-1", "A0A061HUS7-1", "A0A061HVM6-1", "A0A061I033-1", "A0A061I8L6-1", "A0A8C2MQS3-1", "A0A9J7F0Y2-1", "A0A061ILI7-1", "A0A9J7EZ49-1", "A0A8C2M9B6-1", "A0A8C2ML15-1", "A0A8C2LY02-1", "A0A8C2LZT2-1", "A0A8C2M165-1", "A0A8C2M5G2-1", "A0A8C2M3Y9-1", "A0A8C2M5A7-1", "A0A8C2M6A3-1", "A0A8C2MBW2-1", "A0A9J7JYU7-1", "A0A8C2MJ02-1", "A0A9J7JQD1-1", "A0A8C2MMQ4-1", "A0A8C2MQ73-1", "A0A8C2MQL9-1", "A0A9J7KE81-1", "A0A9J7JPE2-1", "A0A8C2LMC9-1", "A0A3L7I870-1", "A0A3L7IB60-1", "A0A3L7IBX6-1", "A0A3L7ID00-1", "A0A3L7IEL5-1", "A0A3L7IER1-1", "A0A8C2L7R1-1", "A0A8C2LC89-1", "A0A8C2LCN7-1", "A0A8C2LDQ8-1", "A0A8C2LEI8-1", "A0A8C2LH99-1", "A0A8C2LHE9-1", "A0A9J7GAB0-1", "A0A8C2LK72-1", "A0A8C2LMJ0-1", "A0A8C2LPR4-1", "A0A8C2LQB2-1", "A0A8C2LVV5-1", "P50310-1", "A0A8C2N4W2-1", "A0A9J7F0N6-1", "A0A9J7F3R3-1", "A0A8C2MV78-1", "A0A8C2MYH0-1", "A0A9J7JHJ2-1", "A0A8C2N0J6-1", "A0A8C2N210-1", "A0A8C2N457-1", "A0A8C2N756-1", "A0A8C2QGY5-1", "A0A8C2QJ34-1", "A0A8C2QJA4-1", "A0A9J7KDV7-1", "A0A8C2QNX2-1", "A0A8C2QPB0-1", "A0A9J7EVN3-1", "A0A8C2M6E6-1", "A0A9J7F2L0-1", "A0A9J7F5B0-1", "A0A8C2LDE5-1", "A0A9J7JB60-1", "A0A9J7F927-1", "A0A9J7FLY5-1", "A0A9J7F8V5-1", "A0A9J7F8T0-1", "A0A9J7FBT0-1", "A0A9J7FD79-1", "A0A9J7K2Q7-1", "A0A3L7I1R2-1", "A0A9J7FS53-1", "A0A9J7G9D1-1", "A0A9J7GD76-1", "A0A9J7FN68-1", "A0A9J7FNF0-1", "A0A9J7FUL0-1", "A0A9J7FVR6-1", "A0A9J7FYY3-1", "A0A9J7FZH7-1", "A0A9J7FZW1-1", "A0A9J7G1H0-1", "A0A9J7G5N9-1", "A0A8C2LFT9-1", "A0A9J7GBI2-1", "A0A8C2MB66-1", "A0A8C2LQS5-1", "A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3E2-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7F9C4-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2M7I3-1", "A0A8C2N3I1-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A9J7JQZ1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A3L7I1E7-1", "A0A9J7GBL6-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7H540-1", "A0A9J7H949-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H8W5-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GQY0-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7JPF2-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K3L1-1", "A0A9J7K6R5-1", "A0A9J7KB54-1", "A0A9J7K851-1", "A0A9J7KCM5-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7JA07-1", "A0A3L7HMX8-1", "A0A061HZ27-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2MP62-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "A0A9J7JYC5-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3HX91-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", "A0A8C2QND0-1", "G3HXQ8-1", "A0A8C2M0A2-1", "A0A9J7K2S5-1", "A0A8C2MMZ5-1", "A0A8C2QH69-1", "A0A8C2QL63-1", "A0A9J7K953-1", "A0A9J7JBH0-1", "A0A9J7FEY2-1", "A0A9J7FGD3-1", "A0A9J7FKM1-1", "A0A9J7JKJ1-1", "A0A9J7G3C1-1", "A0A9J7G180-1", "A0A9J7JTL3-1", "A0A9J7GFS3-1", "A0A9J7GQ42-1", "A0A9J7EZ53-1", "A0A9J7J5Z8-1", "A0A9J7F0G6-1", "A0A9J7FCC7-1", "A0A9J7EVK4-1", "A0A9J7K3S4-1", "A0A9J7GAF4-1", "A0A9J7GBF4-1", "A0A8C2MTI7-1", "A0A9J7J1N3-1", "A0A9J7F4P4-1", "A0A9J7JNU2-1", "A0A9J7H3M5-1", "A0A9J7JJV6-1", "A0A9J7GJE4-1", "A0A8C2LY52-1", "A0A9J7H8U3-1", "A0A9J7F821-1", "A0A8C2N185-1", "A0A9J7KFV8-1", "A0A8C2MQM0-1", "A0A8C2N310-1", "A0A9J7H6V8-1", "A0A9J7H2P9-1", "A0A9J7H4N5-1", "A0A3L7GPC7-1", "A0A9J7J6H1-1", "A0A3L7HV37-1", "A0A8C2LTZ7-1", "A0A9J7K7D8-1", "A0A9J7JXM2-1", "A0A8C2LDU9-1", "A0A8C2LTW4-1", "A0A9J7JAM4-1", "A0A9J7JRJ8-1", "A0A8C2QEB8-1", "A0A3L7HKC4-1", "A0A8C2LI14-1", "A0A8C2QDX9-1", "A0A9J7G1D9-1", "A0A9J7F985-1", "A0A9J7G270-1", "A0A9J7K1H4-1", "A0A8C2MCX3-1", "A0A8C2MEU5-1", "A0A8C2MFN1-1", "A0A8C2MMI4-1", "A0A9J7JAB2-1", "A0A9J7G969-1", "A0A8C2MQ42-1", "A0A8C2MR08-1", "A0A8C2MUQ5-1", "A0A9J7FZA7-1", "A0A8C2N3C9-1", "A0A8C2N6L4-1", "A0A8C2N9X1-1", "A0A8C2QHF9-1", "A0A8C2QI80-1", "A0A8C2QKP7-1", "A0A9J7FFS7-1", "A0A9J7FI14-1", "A0A9J7FJ23-1", "A0A9J7JLH7-1", "A0A8C2MH43-1", "A0A9J7FZ18-1", "A0A9J7G368-1", "A0A9J7G6S5-1", "A0A9J7H2T6-1", "A0A9J7H3N1-1", "A0A9J7H8L4-1", "A0A9J7JIW6-1", "A0A9J7JRI3-1", "A0A061ILI7-1", "A0A061HUS7-1", "A0A061HVM6-1", "A0A061I033-1", "A0A061I8L6-1", "A0A061I9F9-1", "A0A8C2MQS3-1", "A0A9J7F0Y2-1", "A0A9J7EZ49-1", "A0A8C2M6A3-1", "A0A8C2MQL9-1", "A0A8C2LY02-1", "A0A8C2LZT2-1", "A0A8C2M165-1", "A0A8C2M5G2-1", "A0A8C2M3Y9-1", "A0A8C2M5A7-1", "A0A8C2M9B6-1", "A0A8C2MBW2-1", "A0A9J7JYU7-1", "A0A8C2MJ02-1", "A0A8C2ML15-1", "A0A9J7JQD1-1", "A0A8C2MMQ4-1", "A0A8C2MQ73-1", "A0A9J7KE81-1", "A0A9J7JPE2-1", "A0A9J7F773-1", "A0A8C2L7R1-1", "A0A8C2LHE9-1", "A0A3L7I870-1", "A0A3L7IB60-1", "A0A3L7IBX6-1", "A0A3L7ID00-1", "A0A3L7IEL5-1", "A0A3L7IER1-1", "A0A8C2LC89-1", "A0A8C2LCN7-1", "A0A8C2LEI8-1", "A0A8C2LH99-1", "A0A9J7GAB0-1", "A0A8C2LK72-1", "A0A8C2LMC9-1", "A0A8C2LMJ0-1", "A0A9J7JQV6-1", "A0A8C2LPR4-1", "A0A8C2LQB2-1", "A0A8C2LVV5-1", "A0A8C2MYH0-1", "A0A8C2MV78-1", "A0A9J7JHJ2-1", "A0A8C2N0J6-1", "A0A8C2N210-1", "A0A8C2N457-1", "A0A8C2N4W2-1", "A0A8C2N756-1", "A0A8C2QGY5-1", "A0A8C2QJ34-1", "A0A8C2QJA4-1", "A0A9J7KDV7-1", "A0A8C2QNX2-1", "A0A8C2QPB0-1", "A0A9J7EVN3-1", "A0A9J7F0N6-1", "A0A8C2M6E6-1", "A0A9J7F2L0-1", "A0A9J7F3R3-1", "A0A9J7F5B0-1", "A0A8C2LDE5-1", "A0A9J7JB60-1", "A0A9J7F927-1", "A0A9J7F8V5-1", "A0A9J7F8T0-1", "A0A9J7FBT0-1", "A0A9J7FD79-1", "A0A9J7FLY5-1", "A0A9J7K2Q7-1", "A0A3L7I1R2-1", "A0A9J7FYY3-1", "A0A9J7GBI2-1", "A0A9J7FN68-1", "A0A9J7FNF0-1", "A0A9J7FS53-1", "A0A9J7FUL0-1", "A0A9J7FVR6-1", "A0A9J7FZH7-1", "A0A9J7FZW1-1", "A0A9J7G1H0-1", "A0A9J7G5F3-1", "A0A9J7G5N9-1", "A0A8C2LFT9-1", "A0A9J7G9D1-1", "A0A8C2MB66-1", "A0A9J7GD76-1", "A0A8C2LQS5-1", "A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GT89-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JIF8-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7F9C4-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A8C2M7I3-1", "A0A8C2MBI9-1", "A0A9J7JQZ1-1", "A0A8C2N3I1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7GBL6-1", "A0A9J7H8W5-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7H540-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H949-1", "A0A9J7GQY0-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] } ] }, { "uniprot_ac": "A0A8C2M3Y9", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] } ] }, { "uniprot_ac": "A0A8C2M497", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] } ] }, { "uniprot_ac": "A0A8C2N457", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] } ] }, { "uniprot_ac": "A0A8C2N4W2", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": 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"evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] } ] }, { "uniprot_ac": "A0A9J7G5N9", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": 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"ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] } ] }, { "uniprot_ac": "A0A9J7GAF4", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] } ] }, { "uniprot_ac": "A0A9J7GF59", "gene_name": "LOC103160391", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] } ] }, { "uniprot_ac": "A0A9J7GIN7", "gene_name": "Eif2ak3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] } ] }, { "uniprot_ac": "A0A9J7GJE4", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] } ] }, { "uniprot_ac": "A0A9J7GK55", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] } ] }, { "uniprot_ac": "A0A9J7GLT3", "gene_name": "LOC113838166", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] } ] }, { "uniprot_ac": "A0A9J7GMF3", "gene_name": "LOC103158537", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] } ] }, { "uniprot_ac": "A0A9J7GMK5", "gene_name": "Sbk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] } ] }, { "uniprot_ac": "A0A9J7GP29", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] } ] }, { "uniprot_ac": "A0A9J7GQ42", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] } ] }, { "uniprot_ac": "A0A9J7GQY0", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] } ] }, { "uniprot_ac": "A0A9J7GR05", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] } ] }, { "uniprot_ac": "A0A9J7GR29", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR29", "database": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H2E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H2E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2E9" } ] } ] }, { "uniprot_ac": "A0A9J7H2P9", "gene_name": "LOC113839030", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H2P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H2P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P9" } ] } ] }, { "uniprot_ac": "A0A9J7H2T6", "gene_name": "Ttn", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H2T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2T6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H2T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2T6" } ] } ] }, { "uniprot_ac": "A0A9J7H3E2", "gene_name": "LOC113836728", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "A0A9J7H3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E2" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "A0A9J7H3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E2" } ] } ] }, { "uniprot_ac": "A0A9J7H3L8", "gene_name": "Csnk2a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] } ] }, { "uniprot_ac": "A0A9J7H3M5", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] } ] }, { "uniprot_ac": "A0A9J7H3N1", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3N1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3N1" } ] } ] }, { "uniprot_ac": "A0A9J7H3S8", "gene_name": "Wnk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S8" } ] } ] }, { "uniprot_ac": "A0A9J7H401", "gene_name": "Akt2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H401", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H401" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H401", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H401" } ] } ] }, { "uniprot_ac": "A0A9J7H4N5", "gene_name": "LOC113837096", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H4N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H4N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5" } ] } ] }, { "uniprot_ac": "A0A9J7H4T9", "gene_name": "Ciita", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H4T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H4T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4T9" } ] } ] }, { "uniprot_ac": "A0A9J7H503", "gene_name": "LOC100752185", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H503", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H503" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H503", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H503" } ] } ] }, { "uniprot_ac": "A0A9J7H540", "gene_name": "LOC113837157", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540" } ] } ] }, { "uniprot_ac": "A0A9J7H5D8", "gene_name": "Nek8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H5D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H5D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5D8" } ] } ] }, { "uniprot_ac": "A0A9J7H6V8", "gene_name": "Sbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H6V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H6V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8" } ] } ] }, { "uniprot_ac": "A0A9J7H7J5", "gene_name": "Prkacb", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H7J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J5" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7H7J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J5" } ] } ] }, { "uniprot_ac": "A0A9J7H7W6", "gene_name": "LOC113837158", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H7W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H7W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6" } ] } ] }, { "uniprot_ac": "A0A9J7H8E3", "gene_name": "Map3k15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7H8E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3" } ] } ] }, { "uniprot_ac": "A0A9J7H8L4", "gene_name": "Irak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8L4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H8L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8L4" } ] } ] }, { "uniprot_ac": "A0A9J7H8U3", "gene_name": "Wnk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H8U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U3" } ] } ] }, { "uniprot_ac": "A0A9J7H8W5", "gene_name": "Nrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H8W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8W5" } ] } ] }, { "uniprot_ac": "A0A9J7H8W9", "gene_name": "LOC100767231", "activity": [ { "ec_number": "2.7.11.1", "activity": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ] } ] }, { "uniprot_ac": "A0A9J7J1N3", "gene_name": "Limk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J1N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J1N3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7J1N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J1N3" } ] } ] }, { "uniprot_ac": "A0A9J7J5Z8", "gene_name": "Camk2g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"https://www.uniprot.org/uniprotkb/A0A9J7JBH0" } ] } ] }, { "uniprot_ac": "A0A9J7JDU1", "gene_name": "Cdc42bpg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JDU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDU1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JDU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDU1" } ] } ] }, { "uniprot_ac": "A0A9J7JGG9", "gene_name": "Riok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JGG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGG9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JGG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGG9" } ] } ] }, { "uniprot_ac": "A0A9J7JGQ1", "gene_name": "Trpm6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGQ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGQ1" } ] } ] }, { "uniprot_ac": "A0A9J7JGR2", "gene_name": "Rock1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JGR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A9J7JGR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR2" } ] } ] }, { "uniprot_ac": "A0A9J7JHJ2", "gene_name": "Mast2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = 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Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 15% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H705", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H705" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H705", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H705" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753580", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753580", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H705", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H705" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H705", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H705" } ], "pmid": "" }, { "name": "tumor necrosis factor-mediated signaling pathway", "id": "GO:0033209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033209", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H705", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H705" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H705", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H705" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H705", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H705" }, { "id": "PF09257", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09257" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BCMA TALL-1 binding", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 40, "start_aa": "Cys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H709-1", "uniprot_ac": "A0A9J7H709", "uniprot_id": "A0A9J7H709_CRIGR", "mass": { "chemical_mass": 165288.0, "monoisotopic_mass": 165288.0 }, "refseq": { "ac": "XP_035306101", "name": "protein Shroom2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306101" }, "gene_names": [ { "name": "Shroom2", "type": "recommended", "evidence": [ { "id": "A0A9J7H709", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H709" } ] }, { "name": "Shroom2", "type": "synonym", "evidence": [ { "id": "XP_035306101", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306101" } ] } ], "protein_names": [ { "name": "Protein Shroom2 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H709", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H709/entry#names_and_taxonomy" } ] }, { "name": "protein Shroom2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035306101", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306101" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306101", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306101" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H709", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H709" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Shroom2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H709", "locus": {} } ], "crossref": [ { "id": "cd06750", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06750", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751470", "url": "https://www.ncbi.nlm.nih.gov/gene/100751470", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027685", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027685", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751470", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751470", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H709", "url": "https://www.orthodb.org/?gene=A0A9J7H709", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15012:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15012:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08687", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08687", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08688", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08688", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306101", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306101", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GK90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GK90-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H709", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H709", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H709-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H709-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGAEPRARPERLAEAEARAADGVRLVEVHLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDVNLSGFRQEAICLVKGSHKTLKLVVKRKSDPSWRPHSWHATKFFDTLHEPAASLFLSTSGSPSWKSQHHASSSSHDLSGSWEHPSLQRTSDHFSSVGSIDSLDHSSQLYPSGHLLSAKSNNSIDHLGGHSKRDSAYGSFSTCSSTPDHTLPKADASSTENILYKVGLWEASRSGNSRQSQSASDPQGLQDRPPCFTPRVLGNSSKSPRPEDNVEPKTTNSGRSNFGPVWYVPDKKKAPSSPPPLAPPSSSDSFAVAVRSHEKGRGPPVSDLASMQHFTTLPQVHPWGDRRLETTDRQWKLAHPSSSQQEGHLDCRWLSSDERAGGHTGALARHHFSLSSTDVHFLKSYHGSHHPRQCSDESPRVPSSSRELPHMTPGGGLQDPPTLSRDDNPAQVRWSGSANQKLDDRGRSHYFSLPPRQSMQGSAQVVIPRGDYWHSDRTPVDLEYPLLRPLGQRCYLQQHGETMASHEREGYHQLDAGIEGCCSGIQEPPKASHTVKAGLQCRPDDDFKLVDGEGGRISRQRTPMLHSLTQDGAWRPDSNKDCGNEKPPLLDGQMSKPTRRSDRFATTLRNEIQMRRAKLQKSKSTVTLAGDSEAEDCAGDWRANVRAVPEDSFPSTYKEHLKEAQTRVLKATSFQRRDLDPTPADQYPGQSEHRTCDHTASSSLSSFPGELESVPRLCEAGVAKPPSSGGGVPHILRIGGRKRFTAEQKLKSYSEPEKMNEVGISRDHSPHPNVRTPEDTVGTFADRWKFFEETSKSLLQRPNYRQALCGPSREKAERPQTGGSEFESTEPWFQKRSRATSCGEMLSDERKVEKVSEKLNPPRRLGTFAEYQASWKEQRKPLEASSGRYHSADDILDAGLDQQQRPQYIHERSRSSPSTDHYSQESPIEPNRQAEDSGGHKEALQCTLQAEEGFSALSPSVLSSAQPQDGQHVNEVTTVSQPEVQLSSKCQQLQISVMETSRSPSPQFAPQKLTDKPPMLIHEDNSARIERVMDNNTTVKMVPIKIVHSESQPEKESRQSLACPTELPTLPSGLERDQIKSLNTSEQCYSRFCVYTRQEVETPQRSRPPEPQPPSNPAPPVKDICSSPPPLNYGKAKEKTMDDLKSEELAREIVGKDKSLADILDPSVKIKTTMDLMEGIFPKDEYLLEEAQQRRKLLPKVPSPRVTEDKKQDPGVPGVVSLATNSTYYSTSAPKAELLIKMKDLQEPEEYSGGDLDHDLSVKKQELIDSISRKLQVLREARESLLEDIQANNALGDEVEAIVKDVCKPNEFDKFRMFIGDLDKVVNLLLSLSGRLARVENALNNLDDSPSPGDRQSLLEKQRILTQQHEDAKELKENLDRRERIVFDILATYLSEENLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKCLFDSLQPERSK", 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"length": 1485, "header": "tr|A0A9J7H709-1|A0A9J7H709_CRIGR Isoform 1 of Protein Shroom2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Shroom2 PE=3 SV=1 CANONICAL=A0A9J7H709-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 724, "start_aa": "Thr", "end_pos": 724, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr724", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H709", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H709" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304399", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304399" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H718", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H718" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lrrn1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H718", "locus": {} } ], "crossref": [ { "id": "A0A9J7H718", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H718", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, 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"MARLSIGIAACRMVLSLLMTSLTESSILNSECPQLCVCEIRPWFTPQSTYREATTVDCNDLRLTRIPSNLSSDTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQISEMTDYCLQDLSNLQELYINHNQISTISANAFSGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFRPLSNLRSLVLAGMYLTDVPGNALVGLDSLESLSFYDNKLIKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAVYQKTVESLPNLREISIHSNPLRCDCVIHWINSNKTNIRFMEPLSMFCAMPPEYRGQQVKEVLIQDSSEQCLPMISHDTFPNHLNMDIGTTVFLDCRAMAEPEPEIYWVTPIGNKITVETLSDKYKLSNEGTLEIANIQIEDSGRYTCVAQNVQGADTRVAAIKVNGTLLDGAQVLKIYVKQTESHSILVSWKVNSNVMTSNLKWSSATMKIDNPHITYTARVPVDVHEYNLTHLQPSTDYEVCLTVSNIHQQTQKSCVNVTTKNAAFTLDISDHETSTALAAVMGSMFAVISLASIAVYIAKRFKRKNYHHSLKKYMQKTSSIPLNELYPPLINLWEGDSEKDKDGSADTKPTQVDTSRSYYMW", "length": 716, "header": "tr|A0A9J7H718-1|A0A9J7H718_CRIGR Isoform 1 of Leucine-rich repeat neuronal protein 1 OS=Cricetulus griseus OX=10029 GN=Lrrn1 PE=4 SV=1 CANONICAL=A0A9J7H718-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H718-1", "url": 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"gene_names": [ { "name": "LOC100772039", "type": "recommended", "evidence": [ { "id": "A0A9J7H742", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H742" } ] }, { "name": "LOC100772039", "type": "synonym", "evidence": [ { "id": "XP_035304915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304915" } ] } ], "protein_names": [ { "name": "Murinoglobulin-1-like isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H742", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H742/entry#names_and_taxonomy" } ] }, { "name": "murinoglobulin-1-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035304915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304915" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 4% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304915", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304915" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H742", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H742" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100772039", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H742", "locus": {} } ], "crossref": [ { "id": "cd02897", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02897", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772039", "url": "https://www.ncbi.nlm.nih.gov/gene/100772039", "database": "GeneID", "categories": [ 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"length": 1494, "header": "tr|A0A9J7H742-1|A0A9J7H742_CRIGR Isoform 1 of Murinoglobulin-1-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100772039 PE=3 SV=1 CANONICAL=A0A9J7H742-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H742-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H742/entry#A0A9J7H742-1", "sequence": { "sequence": "MMKGRQALQCLISILLAFLPSVSSLDGQHEPEQPKIMVLVPSQLRTKTPEKICLHLYQLSEPVTVKASLKFSWESRSLFNDLVVDKDLFHCVSFTLPRVSSSEEKVSLSVHVKGPKHEFSKTNEVTVKNQENVVFVQTDKPMYKPGQPVKFRVVSMDTNLHPLNELFPLVYIEDPKTNRIMQWRDINTENGLKQLSFSLSSEPILGSYKIVLENQSRSKKEHYFTVEEYVLPRFEVQVKVPKALFIKDEKLKVTVCGVYTYGKPVPGHVKIRTCHKYPLYRRQIETQCKESSSQLDNNGCSTQEEDITELQLKEKTFEDQYLHVNAKITEEGTGLEFSGSGTTKIERTIAKLIFVKADSHFKQGIPFVVKVRLVDVKGAPIPNEEVFIKLWELDYTNKTTTDQHGLAEFSINTTTFNVHFLIIKVYHKEQSSCFHKLCLNEHTESLHMAQSVYSFSWSYIHLEKDAGVLPCSQTHTVRVHFLVKGPVLSALRDLTFYYLVMAKGSIIQTGSHTHHTEPKESPVIGDFDLEIPVELSMAPVTSVFVYTIFPNGEIIADSAKYYVEKCLLNKVDLSFTPARSLPASQAHLQVTASPQSLCGLRAVDQSVLLLRPEAEVSPSWIYNLPEIRNTEYIPTPDQIFQELELCVWTDNPTDEVLLHPDEKDVYGYVKDMGLKAFTNLKIKYRKFCISYGDNYPTVAVPSLGFDDVTNEGDSRTKPEVGQEELVTETIRKYFPETWIWDLVTVNSSGVTEMEVTVPDTITEWKAGVFCLSNDTGLGLSPVVSLQAFKPFFVELTMPYSVIRGEAFTLKATVFNYLPTCIRVGVLLEDSPDFTAVPVAKDQDSHCLCANGRHTESWLVTPKSLGNVNFSVTAEAQQSPEPCGSEVATVPETGKKDTVVKVLIVEPEGIKKEHTFSSLLCASDAKISEKVSLKLPLKVVEDSVRAHFSVQGDILSSAIKNTQNLLHMPFGCGEQNMVLFAPNIYVLKYLNETQQLTQNIKSKAIGYLTEGYQRELNYKHKDGSYSSFGDQDGQSEGNTWLTAFVLKSFAQARAFIFIDEKHITHAFTWLSQQQQDNGCFRSSGSMFNNAMKGGVKDEVTLSAYVTIAFLESSIPDPHPVVSKALTCLESSWKTIQQEGNGNFVYTKALLAYAFALAGNQDKRNEIMKSLDNEAIKEENSIHWERPQKPMQSERSLYKPQAPSAEVEMNAYVLLTLLTAQPAPTPEDLDVALRIVKWLTKQQNPQGGFSSTQDTVVALHALSKYGAVTFAGSQKTPSVTIQSSGTFSRTFQIESSNRLLLQQVSLPDIPGDYDISVSGEGCVYAQTTLRYNVQLEKQESAFTLRVQTLPLTCGNPEGHNSFQISLEISYTGSRPASNMVIVDVKMVSGFIPLKPTVKKLERSEHVSKTEMSNNNVLLYVDQVTNQTLTFSFVIQQDIPVRNLQPAIVKVYDYYETDEVVFAEYSAPCSSGEHLAFLATSLPLASFTTKLPRTFVR", "length": 1494, "header": "tr|A0A9J7H742-1|A0A9J7H742_CRIGR Isoform 1 of Murinoglobulin-1-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100772039 PE=3 SV=1 CANONICAL=A0A9J7H742-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1223, "start_aa": "Thr", "end_pos": 1223, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1223", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H742", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H742" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H742", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H742" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772039", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772039", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protease binding", "id": "GO:0002020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H742", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H742" } ], "pmid": "" }, { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H742", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H742" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H742", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H742" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1423, "end_pos": 1425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 746, "end_pos": 748, "annotation": "n_glycosylation_sequon" }, { "start_pos": 773, "end_pos": 775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 868, "end_pos": 870, "annotation": 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"Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-2-macroglobulin bait region", "eco_id": "ECO_0000259", "start_pos": 460, "end_pos": 610, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H742", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H742" }, { "id": "SM01361", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01361" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-macroglobulin receptor-binding", "eco_id": "ECO_0000259", "start_pos": 1375, "end_pos": 1462, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1223 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1423, "end_pos": 1425 }, { "start_pos": 214, "end_pos": 216 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 412, "end_pos": 414 }, { "start_pos": 746, "end_pos": 748 }, { "start_pos": 773, "end_pos": 775 }, { "start_pos": 868, "end_pos": 870 }, { "start_pos": 990, "end_pos": 992 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H752-1", "uniprot_ac": "A0A9J7H752", "uniprot_id": "A0A9J7H752_CRIGR", "mass": { "chemical_mass": 68393.0, "monoisotopic_mass": 68393.0 }, "refseq": { "ac": "XP_035304931", "name": "LOW QUALITY PROTEIN: glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304931" }, "gene_names": [ { "name": "LOC103159270", "type": "recommended", "evidence": [ { "id": "A0A9J7H752", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752" } ] }, { "name": "LOC103159270", "type": "synonym", "evidence": [ { "id": "XP_035304931", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304931" } ] } ], "protein_names": [ { "name": "glutamine--fructose-6-phosphate transaminase (isomerizing)", "type": "recommended", "evidence": [ { "id": "A0A9J7H752", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752/entry#names_and_taxonomy" } ] }, { "name": "2.6.1.16", "type": "synonym", "evidence": [ { "id": "A0A9J7H752", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "type": "synonym", "evidence": [ { "id": "XP_035304931", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304931" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel assembly gap :: added 106 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) and transcript sequence (IACG01178763.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304931", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304931" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H752", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC103159270", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752", "locus": {} } ], "crossref": [ { "id": "cd00714", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00714", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05008", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05008", "database": "CDD", 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"https://www.ebi.ac.uk/interpro/entry/IPR035490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103159270", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103159270", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H752", "url": "https://www.orthodb.org/?gene=A0A9J7H752", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10937", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10937", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10937:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10937:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13522", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13522", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304931", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304931", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H752", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H752-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGLDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNWESQDVSFTTLVERVIQQLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTGKDKKGSCNLSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDDVAAVVDGRLSIHRIKRTAGDHPGRAVQTLQMEIQQIMKGLKDHITEIQRCQLLILIAVAQVTTLTRQGLEELTELLVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLMGLRYCKERGAVTVGITNTVSSSISRETDCGVHINAGPEIGVASTKSMDDEIQKLXQQKSFLIKGRGYHYATWLEGALKIKEITYMHSEGILAGELKHGSLALLDKLMPVIMIIMRYHTYAKCQNALQQVVAQQGCPVVICDKEDTETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVSDHLCRTMGWLLTRVDFPWNLAKSVTVE", "length": 608, "header": "tr|A0A9J7H752-1|A0A9J7H752_CRIGR Isoform 1 of glutamine--fructose-6-phosphate transaminase (isomerizing) OS=Cricetulus griseus OX=10029 GN=LOC103159270 PE=4 SV=1 CANONICAL=A0A9J7H752-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H752-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752/entry#A0A9J7H752-1", "sequence": { "sequence": "MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGLDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNWESQDVSFTTLVERVIQQLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTGKDKKGSCNLSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDDVAAVVDGRLSIHRIKRTAGDHPGRAVQTLQMEIQQIMKGLKDHITEIQRCQLLILIAVAQVTTLTRQGLEELTELLVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLMGLRYCKERGAVTVGITNTVSSSISRETDCGVHINAGPEIGVASTKSMDDEIQKLXQQKSFLIKGRGYHYATWLEGALKIKEITYMHSEGILAGELKHGSLALLDKLMPVIMIIMRYHTYAKCQNALQQVVAQQGCPVVICDKEDTETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVSDHLCRTMGWLLTRVDFPWNLAKSVTVE", "length": 608, "header": "tr|A0A9J7H752-1|A0A9J7H752_CRIGR Isoform 1 of glutamine--fructose-6-phosphate transaminase (isomerizing) OS=Cricetulus griseus OX=10029 GN=LOC103159270 PE=4 SV=1 CANONICAL=A0A9J7H752-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 404, "start_aa": "Thr", "end_pos": 404, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr404", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H752", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H752", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103159270", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103159270", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H752", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752" } ], "pmid": "" }, { "name": "UDP-N-acetylglucosamine metabolic process", "id": "GO:0006047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006047", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H752", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752" } ], "pmid": "" }, { "name": "fructose 6-phosphate metabolic process", "id": "GO:0006002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006002", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H752", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "glutamine-fructose-6-phosphate transaminase (isomerizing) activity", "id": "GO:0004360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004360", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H752", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752" } ], "pmid": "" }, { "name": "carbohydrate derivative binding", "id": "GO:0097367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097367", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H752", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H752", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752" }, { "id": "PS51278", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51278" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glutamine amidotransferase type-2", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 287, "start_aa": "Cys", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H752", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H752" }, { "id": "PS51464", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51464" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SIS", "eco_id": "ECO_0000259", "start_pos": 323, "end_pos": 438, "start_aa": "His", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.6.1.16", "ec_name": "D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate.", "evidence": [ { "id": "2.6.1.16", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.16" }, { "id": "2.6.1.16", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.6.1.16" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 404 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 237, "end_pos": 239 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { 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}, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": 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"XP_035305615", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305615" } ] } ], "protein_names": [ { "name": "Dachshund homolog 2 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H754/entry#names_and_taxonomy" } ] }, { "name": "dachshund homolog 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305615", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305615" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305615", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305615" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H754", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H754" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dach2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H754", "locus": {} } ], "crossref": [ { "id": "A0A9J7H754", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H754", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21081", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21081", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752459", "url": "https://www.ncbi.nlm.nih.gov/gene/100752459", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752459", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752459", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H754", "url": "https://www.orthodb.org/?gene=A0A9J7H754", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12577", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12577", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12577:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12577:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305615", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305615", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H754", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H754", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H754-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H754-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVSAPPVISATSSSAGVPGGLFRAEPLYSSPGEPPRLTPNLINSFMANNHSGSVGGGGIGGGNSGSSNSNTNECRMVDMHGVKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPGRPPKRSLGVLQDNARLLPHAVPGLLSPGIITPTGITAAAMAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKIQSPLAAPGSQHGIAQAALAGQTSLGGAPTLNPLQQNHLLSNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLSRAGASVIKERIPESPSPAPSLEENHRPGSQTSSHPSSSVSSSPSQMDHHSERMVMMPNNREELIVDQDNGQTIKKFQRDNKEEVPAQIPMMKSPLDKIQLAPGQALPPGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRIELYREREIRENLERQLAVELQSRSTMQKRLKKEKKAKRKLQEALEFESKRREQVEQALKQATASDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGTINSILFRISA", "length": 630, "header": "tr|A0A9J7H754-1|A0A9J7H754_CRIGR Isoform 1 of Dachshund homolog 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dach2 PE=3 SV=1 CANONICAL=A0A9J7H754-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H754-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H754/entry#A0A9J7H754-1", "sequence": { "sequence": "MAVSAPPVISATSSSAGVPGGLFRAEPLYSSPGEPPRLTPNLINSFMANNHSGSVGGGGIGGGNSGSSNSNTNECRMVDMHGVKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPGRPPKRSLGVLQDNARLLPHAVPGLLSPGIITPTGITAAAMAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKIQSPLAAPGSQHGIAQAALAGQTSLGGAPTLNPLQQNHLLSNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLSRAGASVIKERIPESPSPAPSLEENHRPGSQTSSHPSSSVSSSPSQMDHHSERMVMMPNNREELIVDQDNGQTIKKFQRDNKEEVPAQIPMMKSPLDKIQLAPGQALPPGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRIELYREREIRENLERQLAVELQSRSTMQKRLKKEKKAKRKLQEALEFESKRREQVEQALKQATASDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGTINSILFRISA", "length": 630, "header": "tr|A0A9J7H754-1|A0A9J7H754_CRIGR Isoform 1 of Dachshund homolog 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dach2 PE=3 SV=1 CANONICAL=A0A9J7H754-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H754", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H754" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H754", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H754" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752459", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752459", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H754", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H754" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H754", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H754" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H754", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H754" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H754", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H754" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" }, { "start_pos": 608, "end_pos": 610, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H754" }, { "id": "PF02437", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02437" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SKI/SNO/DAC", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 168, "start_aa": "Ser", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 182, "end_pos": 184 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 251, "end_pos": 253 }, { "start_pos": 50, "end_pos": 52 }, { "start_pos": 608, "end_pos": 610 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H762-1", "uniprot_ac": "A0A9J7H762", "uniprot_id": "A0A9J7H762_CRIGR", "mass": { "chemical_mass": 100974.0, "monoisotopic_mass": 100974.0 }, "refseq": { "ac": "XP_035304948", "name": "PAX-interacting protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304948" }, "gene_names": [ { "name": "Paxip1", "type": "recommended", "evidence": [ { "id": "A0A9J7H762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H762" } ] }, { "name": "Paxip1", "type": "synonym", "evidence": [ { "id": "XP_035304948", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304948" } ] } ], "protein_names": [ { "name": "PAX-interacting protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7H762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H762/entry#names_and_taxonomy" } ] }, { "name": "PAX transactivation activation domain-interacting protein", "type": "synonym", "evidence": [ { "id": "A0A9J7H762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H762/entry#names_and_taxonomy" } ] }, { "name": "PAX-interacting protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035304948", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304948" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304948", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304948" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H762", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H762" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Paxip1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H762", "locus": {} } ], "crossref": [ { "id": "A0A9J7H762", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H762", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17710", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17710", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17711", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17711", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17712", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17712", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17714", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17714", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17730", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17730", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774278", "url": "https://www.ncbi.nlm.nih.gov/gene/100774278", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774278", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774278", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H762", "url": "https://www.orthodb.org/?gene=A0A9J7H762", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23196", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23196", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23196:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23196:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00533", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00533", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12738", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12738", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16589", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16589", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304948", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304948", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H762", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H762", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H762-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H762-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 34% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303992", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303992" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100768653", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G2", "locus": {} } ], "crossref": [ { "id": "A0A9J7H7G2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H7G2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100768653", "url": "https://www.ncbi.nlm.nih.gov/gene/100768653", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768653", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768653", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H7G2", "url": "https://www.orthodb.org/?gene=A0A9J7H7G2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47009", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47009", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47009:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47009:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303992", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303992", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H7G2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMHLQVFISGLILLLPAFIESFPKVRGVVGHPVTLPCTYSVSHGVSPMCWGRGACFSDKCKDAVILTNGYYVYYERNNRYHLTGKILQGNVSLTIEKVNESDSGLYCCQVEMKQWNVVQTLTISLRIQPGSDPTRNPPTMTKGFYIGIPITLMLLLLVSIMVITIVIISFNNDINDLPLTVNSCYMYINLMILEVQEVVPTPHPQKISTMGLYIGISVSVVLLLLTGILLTISE", "length": 234, "header": "tr|A0A9J7H7G2-1|A0A9J7H7G2_CRIGR Isoform 1 of Hepatitis A virus cellular receptor 1 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100768653 PE=3 SV=1 CANONICAL=A0A9J7H7G2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H7G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G2/entry#A0A9J7H7G2-1", "sequence": { "sequence": "MMHLQVFISGLILLLPAFIESFPKVRGVVGHPVTLPCTYSVSHGVSPMCWGRGACFSDKCKDAVILTNGYYVYYERNNRYHLTGKILQGNVSLTIEKVNESDSGLYCCQVEMKQWNVVQTLTISLRIQPGSDPTRNPPTMTKGFYIGIPITLMLLLLVSIMVITIVIISFNNDINDLPLTVNSCYMYINLMILEVQEVVPTPHPQKISTMGLYIGISVSVVLLLLTGILLTISE", "length": 234, "header": "tr|A0A9J7H7G2-1|A0A9J7H7G2_CRIGR Isoform 1 of Hepatitis A virus cellular receptor 1 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100768653 PE=3 SV=1 CANONICAL=A0A9J7H7G2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768653", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768653", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G2" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phagocytosis, engulfment", "id": "GO:0006911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006911", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G2" } ], "pmid": "" }, { "name": "positive regulation of mast cell activation", "id": "GO:0033005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033005", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "virus receptor activity", "id": "GO:0001618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001618", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G2" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H7G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 124, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 90, "end_pos": 92 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H7G5-1", "uniprot_ac": "A0A9J7H7G5", "uniprot_id": "A0A9J7H7G5_CRIGR", "mass": { "chemical_mass": 81465.0, "monoisotopic_mass": 81465.0 }, "refseq": { "ac": "XP_035305825", "name": "sodium/hydrogen exchanger 6 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305825" }, "gene_names": [ { "name": "Slc9a6", "type": "recommended", "evidence": [ { "id": "A0A9J7H7G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ] }, { "name": "Slc9a6", "type": "synonym", "evidence": [ { "id": "XP_035305825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305825" } ] } ], "protein_names": [ { "name": "Sodium/hydrogen exchanger", "type": "recommended", "evidence": [ { "id": "A0A9J7H7G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5/entry#names_and_taxonomy" } ] }, { "name": "sodium/hydrogen exchanger 6 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_035305825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305825" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305825" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc9a6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5", "locus": {} } ], "crossref": [ { "id": "A0A9J7H7G5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H7G5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100768229", "url": "https://www.ncbi.nlm.nih.gov/gene/100768229", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002090", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004709", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004709", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768229", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768229", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H7G5", "url": "https://www.orthodb.org/?gene=A0A9J7H7G5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10110", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10110", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10110:SF94", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10110:SF94", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00999", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00999", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305825", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LN96", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LN96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LN96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LN96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GQ20", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GQ20-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGARRGWRQAPVLRGVGRPRARPLQRPLLLLFAVSVFGWAGASDGSGGTTRAMDEEIVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFFFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRYYARLWGYRDELRHGLYPQGAHSLFGEMDRVGVDSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTDSATASAPRRFMGNNSEDALDRELTFGDHELVIRGTRLVLPMDDSEPALNSLDDTRHSPA", "length": 732, "header": "tr|A0A9J7H7G5-1|A0A9J7H7G5_CRIGR Isoform 1 of Sodium/hydrogen exchanger OS=Cricetulus griseus OX=10029 GN=Slc9a6 PE=3 SV=1 CANONICAL=A0A9J7H7G5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LN96-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5/entry#A0A8C2LN96-1", "sequence": { "sequence": "MAGARRGWRQAPVLRGVGRPRARPLQRPLLLLFAVSVFGWAGASDGSGGTTRAMDEEIVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFFFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRVGVDSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTDSATASAPRRFMGNNSEDALDRELTFGDHELVIRGTRLVLPMDDSEPALNSLDDTRHSPA", "length": 702, "header": "tr|A0A8C2LN96-1|A0A8C2LN96_CRIGR Computationally mapped isoform of Sodium/hydrogen exchanger OS=Cricetulus griseus OX=10029 GN=Slc9a6 PE=3 SV=1 CANONICAL=A0A9J7H7G5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GQ20-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5/entry#A0A9J7GQ20-1", "sequence": { "sequence": "MDEEIVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFFFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRVGVDSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTDSATASAPRRFMGNNSEDALDRELTFGDHELVIRGTRLVLPMDDSEPALNSLDDTRHSPA", "length": 649, "header": "tr|A0A9J7GQ20-1|A0A9J7GQ20_CRIGR Computationally mapped isoform of Sodium/hydrogen exchanger OS=Cricetulus griseus OX=10029 GN=Slc9a6 PE=3 SV=1 CANONICAL=A0A9J7H7G5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5/entry#A0A9J7H7G5-1", "sequence": { "sequence": "MAGARRGWRQAPVLRGVGRPRARPLQRPLLLLFAVSVFGWAGASDGSGGTTRAMDEEIVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFFFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRYYARLWGYRDELRHGLYPQGAHSLFGEMDRVGVDSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTDSATASAPRRFMGNNSEDALDRELTFGDHELVIRGTRLVLPMDDSEPALNSLDDTRHSPA", "length": 732, "header": "tr|A0A9J7H7G5-1|A0A9J7H7G5_CRIGR Isoform 1 of Sodium/hydrogen exchanger OS=Cricetulus griseus OX=10029 GN=Slc9a6 PE=3 SV=1 CANONICAL=A0A9J7H7G5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768229", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768229", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "sodium:proton antiporter activity", "id": "GO:0015385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015385", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ], "pmid": "" }, { "name": "potassium:proton antiporter activity", "id": "GO:0015386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015386", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ], "pmid": "" }, { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ], "pmid": "" }, { "name": "axonal spine", "id": "GO:0044308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044308", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of intracellular pH", "id": "GO:0051453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051453", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ], "pmid": "" }, { "name": "sodium ion import across plasma membrane", "id": "GO:0098719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098719", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7G5" } ], "pmid": "" }, { "name": "regulation of 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"monoisotopic_mass": 107027.0 }, "refseq": { "ac": "XP_035304022", "name": "seizure protein 6 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304022" }, "gene_names": [ { "name": "Sez6", "type": "recommended", "evidence": [ { "id": "A0A9J7H7I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7I1" } ] }, { "name": "Sez6", "type": "synonym", "evidence": [ { "id": "XP_035304022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304022" } ] } ], "protein_names": [ { "name": "Seizure protein 6 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H7I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7I1/entry#names_and_taxonomy" } ] }, { "name": "seizure protein 6 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035304022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304022" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304022" } ] }, { "annotation": "May play a role in cell-cell recognition and in neuronal membrane signaling. Seems to be important for the achievement of the necessary balance between dendrite elongation and branching during the elaboration of a complex dendritic arbor. Involved in the development of appropriate excitatory synaptic connectivity.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7I1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7I1#function" }, { "database": "UniProtKB", "id": "ARBA00053515", "url": "https://www.uniprot.org/uniprotkb/ARBA00053515#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7I1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7I1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sez6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7I1", "locus": {} } ], "crossref": [ { "id": "A0A9J7H7I1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H7I1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00033", "url": 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The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7J2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J2#function" }, { "database": "UniProtKB", "id": "ARBA00045555", "url": "https://www.uniprot.org/uniprotkb/ARBA00045555#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7J2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Copz2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J2", "locus": {} } ], "crossref": [ { "id": "A0A9J7H7J2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H7J2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14829", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14829", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761728", "url": "https://www.ncbi.nlm.nih.gov/gene/100761728", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761728", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761728", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H7J2", "url": "https://www.orthodb.org/?gene=A0A9J7H7J2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11043", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11043", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11043:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11043:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01217", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027290460", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290460", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H7J2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIWVHFESGVSFLCQFQEPSLYTIKAVFILDNDGRRLLAKYYDDTFPSMKEQMAFEKNVFNKTSRAESEIAFLGGMTIVYKSSIDLLLYVVGSSSENELMLMSVLACLFDSLSHILRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRTDDTGLTEQSVAQVLQSAKEQIKWSLLK", "length": 188, "header": "tr|A0A9J7H7J2-1|A0A9J7H7J2_CRIGR Isoform 1 of Coatomer subunit zeta OS=Cricetulus griseus OX=10029 GN=Copz2 PE=3 SV=1 CANONICAL=A0A9J7H7J2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H7J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J2/entry#A0A9J7H7J2-1", "sequence": { "sequence": "MIWVHFESGVSFLCQFQEPSLYTIKAVFILDNDGRRLLAKYYDDTFPSMKEQMAFEKNVFNKTSRAESEIAFLGGMTIVYKSSIDLLLYVVGSSSENELMLMSVLACLFDSLSHILRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRTDDTGLTEQSVAQVLQSAKEQIKWSLLK", "length": 188, "header": "tr|A0A9J7H7J2-1|A0A9J7H7J2_CRIGR Isoform 1 of Coatomer subunit zeta OS=Cricetulus griseus OX=10029 GN=Copz2 PE=3 SV=1 CANONICAL=A0A9J7H7J2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7J2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7J2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761728", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761728", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7J2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J2" } ], "pmid": "" }, { "name": "COPI vesicle coat", "id": "GO:0030126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030126", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7J2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7J2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J2" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7J2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J2" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7J2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H7J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J2" }, { "id": "PF01217", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP complex mu/sigma subunit", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 160, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H7J3-1", "uniprot_ac": "A0A9J7H7J3", "uniprot_id": "A0A9J7H7J3_CRIGR", "mass": { "chemical_mass": 96255.0, "monoisotopic_mass": 96255.0 }, "refseq": { "ac": "XP_035304695", "name": "E3 ubiquitin-protein ligase PDZRN3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304695" }, "gene_names": [ { "name": "Pdzrn3", "type": "recommended", "evidence": [ { "id": "A0A9J7H7J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J3" } ] }, { "name": "Pdzrn3", "type": "synonym", "evidence": [ { "id": "XP_035304695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304695" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase PDZRN3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035304695", "database": "RefSeq", "url": 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This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304695", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304695" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pdzrn3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J3", "locus": {} } ], "crossref": [ { "id": "A0A9J7H7J3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H7J3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06715", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06715", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06716", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06716", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752863", "url": "https://www.ncbi.nlm.nih.gov/gene/100752863", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752863", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752863", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H7J3", "url": "https://www.orthodb.org/?gene=A0A9J7H7J3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JWX1", "url": "https://www.orthodb.org/?gene=A0A9J7JWX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15545", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15545", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15545:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15545:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304695", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304695", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H7J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7J3-1", "url": 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"MSASRFLACLSSFPEFLQCWTILWKCKGEETKSLTLVLHRDSGSLGFNIIGGRPCVDNQDGSSSEGIFVSKIVDSGPAAKEGGLQIHDRIIEVNGKDLSRATHDQAVEAFKTAKEPIVVQVLRRTPRTKMFTPASESQLVDTGTQTDITFEHIMALTKMSSPSPPVLDPYLLPEEHPSSHEYYDPNDYMGDIHQDMDREELELEEVGLYRMNSQDKLGLTVCYRTDDEDDIGIYISEIDPNSIAAKDGRIREGDRIIQINGIEVQNREEAVALLTSEENKNFSLLIARPELQLDEGWMDDDRNDFLDDLHMDMLEEQHHQAMQFTASVLQQKKHEEDGGTTDTATILSNQHEKDSGVGRTDESTRNDESSEQENNGEDATASSNPLAGQRKLTCSQDTLGSGDLPFSNESFISADCTDVDYLGIPVDECERFRELLELKCQVQSSSPYSLYYPSSPLDAAGKSDPESVDKELELLNEELRSIELECLSIVRAHKMQQLKEQYRESWMLHHSGFRNYNTSVDVRRHELSDITELPEKSDKDSSSAYNTGESCRSTPLTLEISPDNSLRRMAEGSSEGATANVEAYRPSPKNLLAITEDPEVSTPNYSPSAKELDPSQALESKERRVSDGSRSPTASPKLGSAYLPSYHHSPYKHAHIPAHAQHYQSYMHLIQQKSAVEYAQSQMSLVSMCKDLNSSNSAEPRMEWKVKIRSDGTRYITKRPVRDRLLRERALKIREERSGLTTDDDAMSEMKMGRYWSKEERKQHLVKAKEQRRRREFMMQSRLDCLKEQQAADDRKEMNILELSHKKMMKKRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV", "length": 849, "header": "tr|A0A9J7H7J3-1|A0A9J7H7J3_CRIGR Isoform 1 of E3 ubiquitin-protein ligase PDZRN3 isoform X1 OS=Cricetulus griseus 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##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 39% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304054", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304054" } ] }, { "annotation": "Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription. Necessary for the stability of the TFIIH complex and for the presence of normal levels of TFIIH in the cell.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7K1#function" }, { "database": "UniProtKB", "id": "ARBA00060174", "url": "https://www.uniprot.org/uniprotkb/ARBA00060174#function" } ] }, { "annotation": "In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. 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This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305385", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305385" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7L7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ptprh", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7L7", "locus": {} } ], "crossref": [ { "id": "A0A9J7H7L7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H7L7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, 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"tr|A0A9J7H7L7-1|A0A9J7H7L7_CRIGR Isoform 1 of Receptor-type tyrosine-protein phosphatase H OS=Cricetulus griseus OX=10029 GN=Ptprh PE=4 SV=1 CANONICAL=A0A9J7H7L7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H7L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7L7/entry#A0A9J7H7L7-1", "sequence": { "sequence": 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"tr|A0A9J7H7L7-1|A0A9J7H7L7_CRIGR Isoform 1 of Receptor-type tyrosine-protein phosphatase H OS=Cricetulus griseus OX=10029 GN=Ptprh PE=4 SV=1 CANONICAL=A0A9J7H7L7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7L7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7L7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764809", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764809", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7L7" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7L7", "url": 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"annotation": "n_glycosylation_sequon" }, { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 698, "end_pos": 700, "annotation": "n_glycosylation_sequon" }, { "start_pos": 730, "end_pos": 732, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3H060-1", "G3H622-1", "G3H9Q0-1", "A0A8C2LH05-1", "G3HKY7-1", "G3GWQ6-1", "G3HBF6-1", "G3GRD1-1", "G3H8H2-1", "A0A9J7FG56-1", "A0A061IAM9-1", "A0A9J7GE78-1", "A0A9J7GZK0-1", "A0A061HX98-1", "A0A061HZS8-1", "A0A3L7HEJ5-1", "A0A8C2LYZ8-1", "A0A9J7JC04-1", "A0A8C2MQ28-1", "A0A3L7I231-1", "A0A9J7EY47-1", "A0A8C2LVB9-1", "A0A8C2MZ43-1", "A0A9J7G003-1", 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"evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] } ] }, { "uniprot_ac": "A0A061HZS8", "gene_name": "Ptpn14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HZS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZS8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HZS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZS8" } ] } ] }, { "uniprot_ac": "A0A061IAM9", "gene_name": "LOC100766206", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] } ] }, { "uniprot_ac": "A0A3L7HAL2", "gene_name": "Pgp", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] } ] }, { "uniprot_ac": "A0A3L7HEJ5", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] } ] }, { "uniprot_ac": "A0A3L7I231", "gene_name": "Ptp4a3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] } ] }, { "uniprot_ac": "A0A3L7IA07", "gene_name": "Ptp4a2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] } ] }, { "uniprot_ac": "A0A8C2LH05", "gene_name": "Acp1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] } ] }, { "uniprot_ac": "A0A8C2LVB9", "gene_name": "Dusp22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] } ] }, { "uniprot_ac": "A0A8C2LYZ8", "gene_name": "Ptprf", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] } ] }, { "uniprot_ac": "A0A8C2MFV5", "gene_name": "LOC100758361", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] } ] }, { "uniprot_ac": "A0A8C2MQ28", "gene_name": "Ptprz1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] } ] }, { "uniprot_ac": "A0A8C2MZ43", "gene_name": "Ptprg", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] } ] }, { "uniprot_ac": "A0A8C2N2E5", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] } ] }, { "uniprot_ac": "A0A8C2N686", "gene_name": "Ptp4a1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ] } ] }, { "uniprot_ac": "A0A8C2QC02", "gene_name": "Ptpn6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] } ] }, { "uniprot_ac": "A0A8C2QCP2", "gene_name": "Dusp28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] } ] }, { "uniprot_ac": "A0A8C2QH88", "gene_name": "Dusp12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] } ] }, { "uniprot_ac": "A0A9J7EXY7", "gene_name": "Ptpn13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] } ] }, { "uniprot_ac": "A0A9J7EY47", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] } ] }, { "uniprot_ac": "A0A9J7EZC9", "gene_name": "Ptpn18", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] } ] }, { "uniprot_ac": "A0A9J7EZL1", "gene_name": "LOC113830718", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] } ] }, { "uniprot_ac": "A0A9J7F2A0", "gene_name": "Ptpn12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7F2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2A0" } ] } ] }, { "uniprot_ac": "A0A9J7FB56", "gene_name": "Ptpru", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FB56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FB56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB56" } ] } ] }, { "uniprot_ac": "A0A9J7FEN1", "gene_name": "Eya1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] } ] }, { "uniprot_ac": "A0A9J7FEZ5", "gene_name": "Ptpn2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] } ] }, { "uniprot_ac": "A0A9J7FG56", "gene_name": "Cdc25c", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] } ] }, { "uniprot_ac": "A0A9J7FIV0", "gene_name": "LOC100763249", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] } ] }, { "uniprot_ac": "A0A9J7FKB3", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] } ] }, { "uniprot_ac": "A0A9J7FMB0", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] } ] }, { "uniprot_ac": "A0A9J7FWJ6", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FWX7", "gene_name": "LOC103158664", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] } ] }, { "uniprot_ac": "A0A9J7FYL8", "gene_name": "Ptpn11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] } ] }, { "uniprot_ac": "A0A9J7G003", "gene_name": "Ptprs", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G003" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G003" } ] } ] }, { "uniprot_ac": "A0A9J7G168", "gene_name": "LOC100762307", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ] } ] }, { "uniprot_ac": "A0A9J7G1A0", "gene_name": "Ptpn4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": 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"id": "A0A9J7GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX92" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX92" } ] } ] }, { "uniprot_ac": "A0A9J7GZK0", "gene_name": "Ptprc", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZK0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZK0" } ] } ] }, { "uniprot_ac": "A0A9J7H152", "gene_name": "Ptprt", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H152", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305401", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305401" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7M6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC103162086", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M6", "locus": {} } ], "crossref": [ { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "103162086", "url": "https://www.ncbi.nlm.nih.gov/gene/103162086", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103162086", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103162086", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H7M6", "url": "https://www.orthodb.org/?gene=A0A9J7H7M6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305401", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305401", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H7M6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFFFQTQKPREQEEGRMNAPLVNASQHLVTFRDVSVDLSQEEWECLDCAQRALYVDVMLENYRNLVFVGNRCICHNYENVLDQSSMPIVHQHANTQVKPYKCNQPCSIIHKSSQYTDNTRDSVEICNNYVCGNHRDASVESLNRHKSGNPGEEPCEGKGCINCLSLCSIISRNQRVYAVRKKTENTKHDKFFDSKHDLTLKRTNSGKKPNQSWKCGKSFKTDSSLSRHQRAHTRQKHYKCTKCSKSFLRLSQVKVHCKFHCGEKPYKCMECPKWLYHTSEFKRQFRLHSGENIYKYSEDDKSLITKDHLGPHPRLHTGEKPYKCNECDRSFTQRSSLRTHLRIHMGEKPYKCSECEKCFTQRGHLTNHQRVHTGEKPYKCSECDKSFTKKDHLRIHYRIHTGEKPYKCTDCDKSFTQKSSLITHQRLHMGEKPYRCSECDTCFTQTGHLKIHQRIHTGVKPYKCSDCDRSFTTKDHLRTHQRLHTGEKPYKCSECFKSFISCSNLRKHQKIHXGQEPYKCTETEKSFTSSSSLRRH", "length": 536, "header": "tr|A0A9J7H7M6-1|A0A9J7H7M6_CRIGR Isoform 1 of LOW QUALITY PROTEIN: zinc finger protein 54 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC103162086 PE=3 SV=1 CANONICAL=A0A9J7H7M6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H7M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7M6/entry#A0A9J7H7M6-1", "sequence": { "sequence": "MFFFQTQKPREQEEGRMNAPLVNASQHLVTFRDVSVDLSQEEWECLDCAQRALYVDVMLENYRNLVFVGNRCICHNYENVLDQSSMPIVHQHANTQVKPYKCNQPCSIIHKSSQYTDNTRDSVEICNNYVCGNHRDASVESLNRHKSGNPGEEPCEGKGCINCLSLCSIISRNQRVYAVRKKTENTKHDKFFDSKHDLTLKRTNSGKKPNQSWKCGKSFKTDSSLSRHQRAHTRQKHYKCTKCSKSFLRLSQVKVHCKFHCGEKPYKCMECPKWLYHTSEFKRQFRLHSGENIYKYSEDDKSLITKDHLGPHPRLHTGEKPYKCNECDRSFTQRSSLRTHLRIHMGEKPYKCSECEKCFTQRGHLTNHQRVHTGEKPYKCSECDKSFTKKDHLRIHYRIHTGEKPYKCTDCDKSFTQKSSLITHQRLHMGEKPYRCSECDTCFTQTGHLKIHQRIHTGVKPYKCSDCDRSFTTKDHLRTHQRLHTGEKPYKCSECFKSFISCSNLRKHQKIHXGQEPYKCTETEKSFTSSSSLRRH", "length": 536, "header": "tr|A0A9J7H7M6-1|A0A9J7H7M6_CRIGR Isoform 1 of LOW QUALITY PROTEIN: zinc finger protein 54 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC103162086 PE=3 SV=1 CANONICAL=A0A9J7H7M6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24383", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24383:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24383:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305279", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305279", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H7R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7R2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7R2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7R2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPQPPPPAQGSPPHRGRGRGRGRGRGRGRGRGRGGTGAPRAPLPCPTCGRLFRFPYYLSRHRLSHSGLRPHACPLCPKAFRRPAHLSRHLRGHGPQPPLRCAACPRTFPEPAQLRRHLAQEHAGGEVDVSTQRAVKEEPEASWGPQDEGVEQPSTAAAGGAEEVVAAAAAAAAEWPETWPSGDPAPLAAPTSTDPRESEAKEAEAGAAELRAELALAAGRQEEKQVLLQADWTLLCLRCREAFATKGELKAHPCLRPEGEQEGEGGPPPRPKRHQCSICLKAFARPWSLSRHRLVHSTDRPFVCPDCGLAFRLASYLRQHRRVHGPLSLLAPLPGAGKKDDKSSGGRNSGRGPEGGEGAECGGASEGGEGGQNGGDATPARPPAGEPRFWCPECGKGFRRRAHLRQHGVTHSGARPFQCVRCQREFKRLADLARHAQVHAGGPAPHPCPRCPRRFSRAYSLLRHQRCHRAELERAELERATALQALQSQAAQSPQTPLKQETEGLPLSIAHIKEEPPSPGTPPQSPRAPPVFLSASCFDSQDHSAFEMEDEEVDSKAHLRGLGGLAS", "length": 568, "header": "tr|A0A9J7H7R2-1|A0A9J7H7R2_CRIGR Isoform 1 of Zinc finger protein 579 OS=Cricetulus griseus OX=10029 GN=LOC113837246 PE=3 SV=1 CANONICAL=A0A9J7H7R2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H7R2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7R2/entry#A0A9J7H7R2-1", "sequence": { "sequence": "MDPQPPPPAQGSPPHRGRGRGRGRGRGRGRGRGRGGTGAPRAPLPCPTCGRLFRFPYYLSRHRLSHSGLRPHACPLCPKAFRRPAHLSRHLRGHGPQPPLRCAACPRTFPEPAQLRRHLAQEHAGGEVDVSTQRAVKEEPEASWGPQDEGVEQPSTAAAGGAEEVVAAAAAAAAEWPETWPSGDPAPLAAPTSTDPRESEAKEAEAGAAELRAELALAAGRQEEKQVLLQADWTLLCLRCREAFATKGELKAHPCLRPEGEQEGEGGPPPRPKRHQCSICLKAFARPWSLSRHRLVHSTDRPFVCPDCGLAFRLASYLRQHRRVHGPLSLLAPLPGAGKKDDKSSGGRNSGRGPEGGEGAECGGASEGGEGGQNGGDATPARPPAGEPRFWCPECGKGFRRRAHLRQHGVTHSGARPFQCVRCQREFKRLADLARHAQVHAGGPAPHPCPRCPRRFSRAYSLLRHQRCHRAELERAELERATALQALQSQAAQSPQTPLKQETEGLPLSIAHIKEEPPSPGTPPQSPRAPPVFLSASCFDSQDHSAFEMEDEEVDSKAHLRGLGGLAS", "length": 568, "header": "tr|A0A9J7H7R2-1|A0A9J7H7R2_CRIGR Isoform 1 of Zinc finger protein 579 OS=Cricetulus griseus OX=10029 GN=LOC113837246 PE=3 SV=1 CANONICAL=A0A9J7H7R2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { 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"predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 522, "start_aa": "Thr", "end_pos": 522, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr522", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7R2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7R2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113837246", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837246", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7R2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7R2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7R2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7R2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7R2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 71, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 48, 379, 522 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H7S3-1", "uniprot_ac": "A0A9J7H7S3", "uniprot_id": "A0A9J7H7S3_CRIGR", "mass": { "chemical_mass": 91898.0, "monoisotopic_mass": 91898.0 }, "refseq": { "ac": "XP_035304167", "name": "LOW QUALITY PROTEIN: probable E3 ubiquitin-protein ligase MARCHF10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304167" }, "gene_names": [ { "name": "Marchf10", "type": "recommended", "evidence": [ { "id": "A0A9J7H7S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S3" } ] }, { "name": "Marchf10", "type": "synonym", "evidence": [ { "id": "XP_035304167", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304167" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "A0A9J7H7S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S3/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A9J7H7S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S3/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: probable E3 ubiquitin-protein ligase MARCHF10", "type": "synonym", "evidence": [ { "id": "XP_035304167", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304167" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304167", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304167" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Marchf10", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7S3", "locus": {} } ], "crossref": [ { "id": "A0A9J7H7S3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H7S3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100771778", "url": "https://www.ncbi.nlm.nih.gov/gene/100771778", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H7W6-1", "uniprot_ac": "A0A9J7H7W6", "uniprot_id": "A0A9J7H7W6_CRIGR", "mass": { "chemical_mass": 69192.0, "monoisotopic_mass": 69192.0 }, "refseq": { "ac": "XP_035304880", "name": "sperm motility kinase 2B-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304880" }, "gene_names": [ { "name": "LOC113837158", "type": "recommended", "evidence": [ { "id": "A0A9J7H7W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6" } ] }, { "name": "LOC113837158", "type": "synonym", "evidence": [ { "id": "XP_035304880", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304880" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A9J7H7W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A9J7H7W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6/entry#names_and_taxonomy" } ] }, { "name": "sperm motility kinase 2B-like", "type": "synonym", "evidence": [ { "id": "XP_035304880", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304880" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304880", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304880" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7W6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113837158", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6", "locus": {} } ], "crossref": [ { "id": "cd14337", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14337", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113837158", "url": "https://www.ncbi.nlm.nih.gov/gene/113837158", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113837158", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837158", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304880", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304880", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H7W6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQGREVCYSCEESFMTDDKMMMSVGHGHFSEMKLAFHVPTVTCVAVKVLRMKKKNASLVEVSIMKSLQHPDIIKLFGMVQSRDTTYLMMEHTSQGDLRHILELGSLQESEARRLFTQILLAMQYCHANHIAHRDIKANNILLNCRGNAKLSGFDLAAKVTPGQKLRDFCSTLLYCAPELLLEKAYDGCAADIWSLGVLLFLMVVGHFPFQDSSSEGVRRQILAANVRIPEHVSRDIFNVIVKMLMIKPHRRPTVDQILMCPMIREGKPHSPPVSTQKHPGTVSRGIVSTMTVMGYKSEEIIDSLRDQKYDQVMATYPILQHQSPGGDCGLEATNNKEVSVTKEVTITKEAAIIQDPTITQEEDMAHEVTMTLEKTTTKEMTMDDGVSMTQTESITEEETIIKHEDIILEATITMEETVAQLRTLTQERTITQEEAITHGQPEDALTRERTITQEDTITKHEDIILEATITMEETVAHLRTLTRERTITQEEAITHGQPEDALTRERTITEEETITHGQPEDALTQERTITQEEAITHGQPEDAGPASSGNRRRSGWKRVKKIMVNCLRHLCCCCLPPAKRRQDSCKTLAPKTRDPAVTHRSSSEEVQPQLRGL", "length": 614, "header": "tr|A0A9J7H7W6-1|A0A9J7H7W6_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=LOC113837158 PE=4 SV=1 CANONICAL=A0A9J7H7W6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H7W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6/entry#A0A9J7H7W6-1", "sequence": { "sequence": "MEQGREVCYSCEESFMTDDKMMMSVGHGHFSEMKLAFHVPTVTCVAVKVLRMKKKNASLVEVSIMKSLQHPDIIKLFGMVQSRDTTYLMMEHTSQGDLRHILELGSLQESEARRLFTQILLAMQYCHANHIAHRDIKANNILLNCRGNAKLSGFDLAAKVTPGQKLRDFCSTLLYCAPELLLEKAYDGCAADIWSLGVLLFLMVVGHFPFQDSSSEGVRRQILAANVRIPEHVSRDIFNVIVKMLMIKPHRRPTVDQILMCPMIREGKPHSPPVSTQKHPGTVSRGIVSTMTVMGYKSEEIIDSLRDQKYDQVMATYPILQHQSPGGDCGLEATNNKEVSVTKEVTITKEAAIIQDPTITQEEDMAHEVTMTLEKTTTKEMTMDDGVSMTQTESITEEETIIKHEDIILEATITMEETVAQLRTLTQERTITQEEAITHGQPEDALTRERTITQEDTITKHEDIILEATITMEETVAHLRTLTRERTITQEEAITHGQPEDALTRERTITEEETITHGQPEDALTQERTITQEEAITHGQPEDAGPASSGNRRRSGWKRVKKIMVNCLRHLCCCCLPPAKRRQDSCKTLAPKTRDPAVTHRSSSEEVQPQLRGL", "length": 614, "header": "tr|A0A9J7H7W6-1|A0A9J7H7W6_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=LOC113837158 PE=4 SV=1 CANONICAL=A0A9J7H7W6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 161, "start_aa": "Thr", "end_pos": 161, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr161", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7W6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7W6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113837158", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837158", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7W6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6" } ], "pmid": "" }, { "name": "tau-protein kinase activity", "id": "GO:0050321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050321", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7W6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7W6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7W6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7W6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", 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"A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", 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"url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] } ] }, { "uniprot_ac": "A0A8C2M3Y9", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] } ] }, { "uniprot_ac": "A0A8C2M497", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] } ] }, { "uniprot_ac": "A0A8C2N185", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] } ] }, { "uniprot_ac": "A0A8C2N210", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] } ] }, { "uniprot_ac": "A0A8C2N3I1", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] } ] }, { "uniprot_ac": "A0A8C2N3U2", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] } ] }, { "uniprot_ac": "A0A8C2N457", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] } ] }, { "uniprot_ac": "A0A8C2N4W2", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] } ] }, { "uniprot_ac": "A0A8C2N6L4", "gene_name": "Prkg1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N6L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L4" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8C2N6L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L4" } ] } ] }, { "uniprot_ac": "A0A8C2N756", "gene_name": "Map2k5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N756" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2N756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N756" } ] } ] }, { "uniprot_ac": "A0A8C2N9X1", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N9X1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2N9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N9X1" } ] } ] }, { "uniprot_ac": "A0A8C2QDX9", "gene_name": "Csnk1g1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] } ] }, { 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"ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] } ] }, { "uniprot_ac": "A0A8C2QLT0", "gene_name": "Nek9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] } ] }, { "uniprot_ac": "A0A8C2QMB3", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] } ] }, { "uniprot_ac": "A0A8C2QND0", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] } ] }, { "uniprot_ac": "A0A8C2QNX2", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": 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} ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F821", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] } ] }, { "uniprot_ac": "A0A9J7F8T0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] } ] }, { "uniprot_ac": "A0A9J7G5N9", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": 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"ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] } ] }, { "uniprot_ac": "A0A9J7GAF4", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8W9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H8W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8W9" } ] } ] }, { "uniprot_ac": "A0A9J7H949", "gene_name": "LOC100750729", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H949" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H949" } ] } ] }, { "uniprot_ac": "A0A9J7HEQ9", "gene_name": "LOC113838165", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ] } ] }, { "uniprot_ac": "A0A9J7J1N3", "gene_name": "Limk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J1N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J1N3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7J1N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J1N3" } ] } ] }, { "uniprot_ac": "A0A9J7J5Z8", "gene_name": "Camk2g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7J5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8" } ] } ] }, { "uniprot_ac": "A0A9J7J6E9", "gene_name": "Vrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J6E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7J6E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6E9" } ] } ] }, { "uniprot_ac": "A0A9J7J6H1", "gene_name": "LOC100752268", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J6H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6H1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7J6H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6H1" } ] } ] }, { "uniprot_ac": "A0A9J7J728", "gene_name": "LOC113832236", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J728", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J728" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7J728", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J728" } ] } ] }, { "uniprot_ac": "A0A9J7JA07", "gene_name": "LOC100750629", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA07" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA07" } ] } ] }, { "uniprot_ac": "A0A9J7JAB2", "gene_name": "Stk24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAB2" } ] } ] }, { "uniprot_ac": "A0A9J7JAM4", "gene_name": "Sik1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JAM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAM4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JAM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAM4" } ] } ] }, { "uniprot_ac": "A0A9J7JB60", "gene_name": "Dclk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JB60" } ] } ] }, { "uniprot_ac": "A0A9J7JBH0", "gene_name": "Srpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JBH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JBH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH0" } ] } ] }, { "uniprot_ac": "A0A9J7JDU1", "gene_name": "Cdc42bpg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JDU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDU1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JDU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDU1" } ] } ] }, { "uniprot_ac": "A0A9J7JGG9", "gene_name": "Riok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JGG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGG9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JGG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGG9" } ] } ] }, { "uniprot_ac": "A0A9J7JGQ1", "gene_name": "Trpm6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGQ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGQ1" } ] } ] }, { "uniprot_ac": "A0A9J7JGR2", "gene_name": "Rock1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JGR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A9J7JGR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR2" } ] } ] }, { "uniprot_ac": "A0A9J7JHJ2", "gene_name": "Mast2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JQZ1", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] } ] }, { "uniprot_ac": "A0A9J7JRI3", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": 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This record is derived from a genomic sequence (NW_003615953.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035293228", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293228" } ] }, { "annotation": "Central receptor component of the translocase of the outer membrane of mitochondria (TOM) complex essential for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOMM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore. The TOM complex associates with the ion channel VDAC2 and PINK1 kinase at depolarized mitochondria, this interaction stabilizes PINK1 at the outer mitochondrial membrane and triggers downstream mitophagy by the recruitment of the E3 ubiquitin ligase PRKN. Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7X6#function" }, { "database": "UniProtKB", "id": "ARBA00094332", "url": "https://www.uniprot.org/uniprotkb/ARBA00094332#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7X6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100761610", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7X6", "locus": {} } ], "crossref": [ { "id": "100761610", "url": "https://www.ncbi.nlm.nih.gov/gene/100761610", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761610", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761610", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H7X6", "url": "https://www.orthodb.org/?gene=A0A9J7H7X6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12430", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12430", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12430:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12430:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02064", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02064", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035293228", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293228", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H7X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7X6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGQNSDIAVGICSSLFIRYHIYFDCKRRSDPNFKNRLQERRKKQKLAKERTGLSKLHYLKDAEAVQKFFLEEIQLGEELLAQSEYEKGVDNLKNAIVVCAQPQQLLQXTLPPPXFQMLLTKLPTISQRTVSAQTLAEDDVE", "length": 142, "header": "tr|A0A9J7H7X6-1|A0A9J7H7X6_CRIGR Isoform 1 of Mitochondrial import receptor subunit TOM20 homolog OS=Cricetulus griseus OX=10029 GN=LOC100761610 PE=3 SV=1 CANONICAL=A0A9J7H7X6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H7X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7X6/entry#A0A9J7H7X6-1", "sequence": { "sequence": "MVGQNSDIAVGICSSLFIRYHIYFDCKRRSDPNFKNRLQERRKKQKLAKERTGLSKLHYLKDAEAVQKFFLEEIQLGEELLAQSEYEKGVDNLKNAIVVCAQPQQLLQXTLPPPXFQMLLTKLPTISQRTVSAQTLAEDDVE", "length": 142, "header": "tr|A0A9J7H7X6-1|A0A9J7H7X6_CRIGR Isoform 1 of Mitochondrial import receptor subunit TOM20 homolog OS=Cricetulus griseus OX=10029 GN=LOC100761610 PE=3 SV=1 CANONICAL=A0A9J7H7X6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7X6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7X6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761610", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761610", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7X6" } ], "pmid": "" }, { "name": "protein targeting", "id": "GO:0006605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006605", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7X6" } ], "pmid": "" }, { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7X6" } ], "pmid": "" }, { "name": "tRNA import into mitochondrion", "id": "GO:0016031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016031", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7X6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial outer membrane translocase complex", "id": "GO:0005742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005742", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7X6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein transmembrane transporter activity", "id": "GO:0008320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008320", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7X6" } ], "pmid": "" }, { "name": "mitochondrion targeting sequence binding", "id": "GO:0030943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030943", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7X6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H7Y7-1", "uniprot_ac": "A0A9J7H7Y7", "uniprot_id": "A0A9J7H7Y7_CRIGR", "mass": { "chemical_mass": 168644.0, "monoisotopic_mass": 168644.0 }, "refseq": { "ac": "XP_035304914", "name": "murinoglobulin-1-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304914" }, "gene_names": [ { "name": "LOC100760619", "type": "recommended", "evidence": [ { "id": "A0A9J7H7Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Y7" } ] }, { "name": "LOC100760619", "type": "synonym", "evidence": [ { "id": "XP_035304914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304914" } ] } ], "protein_names": [ { "name": "Murinoglobulin-1-like isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H7Y7", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304914", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304914" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7Y7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Y7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100760619", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Y7", "locus": {} } ], "crossref": [ { "id": "cd02897", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02897", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760619", "url": "https://www.ncbi.nlm.nih.gov/gene/100760619", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047565", "url": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07677", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07677", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07678", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07678", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07703", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07703", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { 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"length": 1502, "header": "tr|A0A9J7H7Y7-1|A0A9J7H7Y7_CRIGR Isoform 1 of Murinoglobulin-1-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100760619 PE=3 SV=1 CANONICAL=A0A9J7H7Y7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H7Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Y7/entry#A0A9J7H7Y7-1", "sequence": { "sequence": "MKKGRKALQCLLSVLLAFLPSASSFYGQPKFMALVPSQLRTETPEKICLHLYQLSEPVTVKASLQFSWGSRSLFNDLVVDKDMFHCVSFTLPRVSSSEEKVSLSVHVKGPKHEFSQTNEVMVKNQENVVFVQTDKPMYKPGQPVKFRVVAMDTNLHPLNELFPLAYIEDPKTNRIMQWRDINTENGLKQLSFSLSSEPILGSYKIVLQKQSGVKREHYFTVEEFVLPRFEVRVKVPKAIFFKDEKMNVTVCGVYTYGKPVPGHVKIRTCHKYQQYRRQIETQCRESSYQLDNNGCSTQEEDITELQLKEKTFEDQYLHVNAKITEEGTGLEFSGSGSTKIERAAIKLIFVKADSHFKQGIPFIVKVRLVDVKGAPIPNEEVFIKPRELDYTNVTTTDQHGLAEFSINTTNFDKHSLTIKVYHKEESSCFHKLCLNEHTESLHVAHSVYSFSRSYIQLEKDTGILPCSQTHTVRVHFIVKGRVVITMRDLTFYYLVMAKDSIIQTGSYTHDMEPEKSPVKGDFDLQIPGELSMAPVISVLVYTIFPNGEIIADSAKFYVEKCLLNRVDLSFTPARSLPASQVHLQVTASPLSLCGLRAVDQSVLLLRPEAELSPSWIYNLPEMRQTEFIPTLDQLFQELEPCVETNKPTDEVLLHPDEKDVYHYVKDMGLKAFTNLKIKHRKFCLPLLCMDFCIVWISDPRVCTYTPFMPSLGFDDVTNKGDSRTMPEVGHEDLATETIRKYFPETWIWDLVTVNSSGVTEMEVTVPDTITEWKAGALCLSNDTGLGLSPVVSLQAFQPFFVELTMPYSVIRGEAFTLKATVFNYLPTCIRVGVLLEDSPDFTAVPVAKDQDSHCLCANGRHTASWLVTPKSLGNVNFSVTAEAQQSPEPCGSEVATVPETGKKDTVVKVLIVEPEGIKKEHTFSSLLCASDAKISEKVSLKLPSKVVEDSVRAHFSVQGDILSSAIKNTQNLLHMPFGCGEQNMVLFAPNIYVLKYLNETQQLTQNIKSKAIGYLTEGYQRELNYKHKDGSYSAFGDQNGQRKGNTWLTAFVLKSFAQARAFIFVDETHITHAFTWLSQQQQDNGCFRSSGSLFNNAMKGGIKDEVTLSAYITIAFLESSIPDTHPVVSKALTCLESSWKTIQQGGNDNLVYTKALLAYAFALAGNQDKRNEILKSLDNEAIKEENSIHWERPQKPMQSERSLYKPQAPSAEVEINAYVLLTLLTAQPAPTPEDLDVALRIVKWLTKQQNPQGGFSSTQDTVVALHALSKYGAVTFAGSQKTPSVTIQSSGTFSRIFQIESSNRLLLQQVLLPDIPGDYDINVSGEGCVYAQTTLRYNVQLEKQESAFTLRVQTLPLTCGNPEGHNSFQISLEISYTGSRPASNMVIVDVKMVSGFIPLKPTVKKLERSEHVSKTEMSTNKVLLYVDQVTNQTLTFSFVIQQDIPVRNLQPAIVKVYDYYETDEVVFAEYSAPCSSGEHLAFLATSLPLASFTPKLPKTFVR", "length": 1502, "header": "tr|A0A9J7H7Y7-1|A0A9J7H7Y7_CRIGR Isoform 1 of Murinoglobulin-1-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100760619 PE=3 SV=1 CANONICAL=A0A9J7H7Y7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1231, "start_aa": "Thr", "end_pos": 1231, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1231", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7Y7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Y7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7Y7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Y7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760619", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760619", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protease binding", "id": "GO:0002020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7Y7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Y7" } ], "pmid": "" }, { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7Y7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Y7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7Y7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Y7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1322, "end_pos": 1324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1431, "end_pos": 1433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 754, "end_pos": 756, "annotation": "n_glycosylation_sequon" }, { "start_pos": 781, "end_pos": 783, "annotation": 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"http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01359" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-2-macroglobulin bait region", "eco_id": "ECO_0000259", "start_pos": 455, "end_pos": 605, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H7Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Y7" }, { "id": "SM01361", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01361" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-macroglobulin receptor-binding", "eco_id": "ECO_0000259", "start_pos": 1383, "end_pos": 1470, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1231 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1322, "end_pos": 1324 }, { "start_pos": 1431, "end_pos": 1433 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 754, "end_pos": 756 }, { "start_pos": 781, "end_pos": 783 }, { "start_pos": 876, "end_pos": 878 }, { "start_pos": 998, "end_pos": 1000 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", 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"uniprot_canonical_ac": "A0A9J7H7Z1-1", "uniprot_ac": "A0A9J7H7Z1", "uniprot_id": "A0A9J7H7Z1_CRIGR", "mass": { "chemical_mass": 149933.0, "monoisotopic_mass": 149933.0 }, "refseq": { "ac": "XP_035307295", "name": "contactin-associated protein-like 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307295" }, "gene_names": [ { "name": "Cntnap2", "type": "recommended", "evidence": [ { "id": "A0A9J7H7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Z1" } ] }, { "name": "Cntnap2", "type": "synonym", "evidence": [ { "id": "XP_035307295", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307295" } ] } ], "protein_names": [ { "name": "Contactin-associated protein-like 2 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Z1/entry#names_and_taxonomy" } ] }, { "name": "contactin-associated protein-like 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035307295", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307295" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307295", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307295" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7Z1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Z1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cntnap2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Z1", "locus": {} } ], "crossref": [ { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00057", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00057", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761620", "url": "https://www.ncbi.nlm.nih.gov/gene/100761620", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003585", "url": 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. 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"categories": [ "Protein Classification" ] }, { "id": "IPR014745", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014745", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761373", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761373", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H805", "url": "https://www.orthodb.org/?gene=A0A9J7H805", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19944", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19944", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19944:SF101", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19944:SF101", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307315", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307315", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H805", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H805", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H805-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H805-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPRVSSLLLAAAVALMVLSSPGAQGTDSPRDSVFQFKGLCYYTNGTQRMRLVNRYIYNREEFVRFDSNVDEFRAVTELGRSWAEDFNSQKEVLEQKRAEMETVCRHNYEQTETTTSLRRREQPKVAVYLTKTEALNHHNLLVCSVTDFYPARIKVRWFRNGQEETVGVVSTKVIQNGDWTYQVLVMLEMTPQRGDVYTCHVEHPSLQSPVSVEWSAQSESAQSKMLSGIGGFVLGLIFLGLGLFIRHRSQKGPRGPPPAGNKYFSPYLGGGAGVWGSYSDSRECLMKLAVAL", "length": 293, "header": "tr|A0A9J7H805-1|A0A9J7H805_CRIGR Isoform 1 of Rano class II histocompatibility antigen, A beta chain isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100761373 PE=3 SV=1 CANONICAL=A0A9J7H805-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H805-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H805/entry#A0A9J7H805-1", "sequence": { "sequence": "MAPRVSSLLLAAAVALMVLSSPGAQGTDSPRDSVFQFKGLCYYTNGTQRMRLVNRYIYNREEFVRFDSNVDEFRAVTELGRSWAEDFNSQKEVLEQKRAEMETVCRHNYEQTETTTSLRRREQPKVAVYLTKTEALNHHNLLVCSVTDFYPARIKVRWFRNGQEETVGVVSTKVIQNGDWTYQVLVMLEMTPQRGDVYTCHVEHPSLQSPVSVEWSAQSESAQSKMLSGIGGFVLGLIFLGLGLFIRHRSQKGPRGPPPAGNKYFSPYLGGGAGVWGSYSDSRECLMKLAVAL", "length": 293, "header": "tr|A0A9J7H805-1|A0A9J7H805_CRIGR Isoform 1 of Rano class II histocompatibility antigen, A beta chain isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100761373 PE=3 SV=1 CANONICAL=A0A9J7H805-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H805", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H805" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H805", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H805" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761373", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761373", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H805", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H805" } ], "pmid": "" }, { "name": "MHC class II protein complex", "id": "GO:0042613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042613", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H805", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H805" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H805", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H805" } ], "pmid": "" }, { "name": "antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "id": "GO:0002504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002504", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H805", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H805" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H805", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H805" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 212, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H807-1", "uniprot_ac": "A0A9J7H807", "uniprot_id": "A0A9J7H807_CRIGR", "mass": { "chemical_mass": 107679.0, "monoisotopic_mass": 107679.0 }, "refseq": { "ac": "XP_035306857", "name": "solute carrier family 5 member 4A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306857" }, "gene_names": [ { "name": "LOC100770560", "type": "recommended", "evidence": [ { "id": "A0A9J7H807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H807" } ] }, { "name": "LOC100770560", "type": "synonym", "evidence": [ { "id": "XP_035306857", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306857" } ] } ], "protein_names": [ { "name": "Solute carrier family 5 member 4A isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H807/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 5 member 4A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035306857", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306857" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306857", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306857" } ] }, { "annotation": "May function as a transcription factor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IEZ5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEZ5#function" }, { "database": "UniProtKB", "id": "ARBA00003729", "url": "https://www.uniprot.org/uniprotkb/ARBA00003729#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H807", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H807" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100770560", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H807", "locus": {} } ], "crossref": [ { "id": "100770560", "url": "https://www.ncbi.nlm.nih.gov/gene/100770560", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038377", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038377", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770560", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770560", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H807", "url": "https://www.orthodb.org/?gene=A0A9J7H807", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11819", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11819", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11819:SF112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11819:SF112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306857", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306857", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7IEZ5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7IEZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H807", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H807", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H807-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H807-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQPFVLCDEEQEPSQAPDEDAELIFVGVEHVNDDSELIFVGMSSNSKPANSNILNRVTPGSRLKRKRNRLRTATTQRPQPSQPSGPATPSSDTVIVLPASPAESRSTDSPIIIEPLSEPDYRSNSPQVVPDSSPEGSPLVTVSSSQHSPPVRAALSVGDLNESSYVSKCHSTSGANAVNPQRPDLIIEIVEEPSPASAPSGTSQTSNPQPSTPASHVPQSLNPVVNGEHSVHNSPTNVHPGQENGLAPGGFSSLASQETPDPKKGSLTLLLSDLYYGQHKGDGQPEQKTHTIFKCPSCLKALKNVKFMNHTKHHVELERQGNDGWESHTTCLHCYRQFTSPFQLECHVDRVHTAPNPATVCKICDLSFETDQVLLQHMKDNHKPGEMPYVCQMGASLFASNIGSGHFVGLAGTGAASGIAVTAFESHSFLFLLILGWFFVPIYIKAGVVTTPEYLRKRFGGQRLQIYLSVLSLFICVALTISSNIFSGAIFIKLAFGLDLYLSIFVLLAITAVFTITGGLASVIYTDTLQAVIMLVGSFILMVFAFIEVGGYENFTEKYMNAIPSVIEGDNLTISPSCYTPRPDSFHIFRDAVTGDIPWPGTIFGMVTTGMWYWCTDQVIVQRCICGKNMSHVKAACIVCGYLKLLPIFFMVMPGMISRILYTDMVACVVPSECVKQCGVDIGCTNYAYPTMVLKLMPMGLRGLMLSVMVASLISSLTSIFNSASTLFTMDLYTKIRKKASERELLIAGRLFVSVLIVTSILWVPIVQVSQGGQLIHYTESISSYLGPPIAAVFLLGIFCKRVNEQGAFWGLMVGLVMGLIRMIAEFSYGTGSCLAASNCPKIICGVHYLYYAIILFSVSALVILGVSFLTKPIPDVHLYRLCWTLRNSEEERIDLDAEEKRDEGADDGTEDDQTEKPRGCLKKTYDLFCGLQKTGPKLTKEEEEVLKKKLTDTSEEPFWRNVVNTNVIVLLAVAVFFYGYFG", "length": 984, "header": "tr|A0A9J7H807-1|A0A9J7H807_CRIGR Isoform 1 of Solute carrier family 5 member 4A isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100770560 PE=3 SV=1 CANONICAL=A0A9J7H807-1" }, "isoforms": [ { "isoform_ac": "A0A3L7IEZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H807/entry#A0A3L7IEZ5-1", "sequence": { "sequence": "MEQPFVLCDEEQEPSQAPDEDAELIFVGVEHVNDDSELIFVGMSSNSKPANSNILNRVTPGSRLKRKRNRLRTATTQRPQPSQPSGPATPSSDTVIVLPASPAESRSTDSPIIIEPLSEPDYRSNSPQVVPDSSPEGSPLVTVSSSQHSPPVRAALSVGDLNESSYVSKCHSTSGANAVNPQRPDLIIEIVEEPSPASAPSGTSQTSNPQPSTPASHVPQSLNPVVNGEHSVHNSPTNVHPGQENGLAPGGFSSLASQETPDPKKGSLTLLLSDLYYGQHKGDGQPEQKTHTIFKCPSCLKALKNVKFMNHTKHHVELERQGNDGWESHTTCLHCYRQFTSPFQLECHVDRVHTAPNPATVCKICDLSFETDQVLLQHMKDNHKPGEMPYVCQVCKYRSSSFSDVDAHFRKCHVNTKNLLCPFCLKIFKTGTPYMCHYRGHWEKNGHQCSKCRLQFLTFKEKMEHKTRCHQIFKRPKHLEGLPPDTKVVIQVSAEPVESESVKVASITVSTTDWEPSSPKSPGRPSKRSH", "length": 530, "header": "tr|A0A3L7IEZ5-1|A0A3L7IEZ5_CRIGR Computationally mapped isoform of Zinc finger protein 280B isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100770560 PE=4 SV=1 CANONICAL=A0A9J7H807-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H807-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H807/entry#A0A9J7H807-1", "sequence": { "sequence": "MEQPFVLCDEEQEPSQAPDEDAELIFVGVEHVNDDSELIFVGMSSNSKPANSNILNRVTPGSRLKRKRNRLRTATTQRPQPSQPSGPATPSSDTVIVLPASPAESRSTDSPIIIEPLSEPDYRSNSPQVVPDSSPEGSPLVTVSSSQHSPPVRAALSVGDLNESSYVSKCHSTSGANAVNPQRPDLIIEIVEEPSPASAPSGTSQTSNPQPSTPASHVPQSLNPVVNGEHSVHNSPTNVHPGQENGLAPGGFSSLASQETPDPKKGSLTLLLSDLYYGQHKGDGQPEQKTHTIFKCPSCLKALKNVKFMNHTKHHVELERQGNDGWESHTTCLHCYRQFTSPFQLECHVDRVHTAPNPATVCKICDLSFETDQVLLQHMKDNHKPGEMPYVCQMGASLFASNIGSGHFVGLAGTGAASGIAVTAFESHSFLFLLILGWFFVPIYIKAGVVTTPEYLRKRFGGQRLQIYLSVLSLFICVALTISSNIFSGAIFIKLAFGLDLYLSIFVLLAITAVFTITGGLASVIYTDTLQAVIMLVGSFILMVFAFIEVGGYENFTEKYMNAIPSVIEGDNLTISPSCYTPRPDSFHIFRDAVTGDIPWPGTIFGMVTTGMWYWCTDQVIVQRCICGKNMSHVKAACIVCGYLKLLPIFFMVMPGMISRILYTDMVACVVPSECVKQCGVDIGCTNYAYPTMVLKLMPMGLRGLMLSVMVASLISSLTSIFNSASTLFTMDLYTKIRKKASERELLIAGRLFVSVLIVTSILWVPIVQVSQGGQLIHYTESISSYLGPPIAAVFLLGIFCKRVNEQGAFWGLMVGLVMGLIRMIAEFSYGTGSCLAASNCPKIICGVHYLYYAIILFSVSALVILGVSFLTKPIPDVHLYRLCWTLRNSEEERIDLDAEEKRDEGADDGTEDDQTEKPRGCLKKTYDLFCGLQKTGPKLTKEEEEVLKKKLTDTSEEPFWRNVVNTNVIVLLAVAVFFYGYFG", "length": 984, "header": "tr|A0A9J7H807-1|A0A9J7H807_CRIGR Isoform 1 of Solute carrier family 5 member 4A isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100770560 PE=3 SV=1 CANONICAL=A0A9J7H807-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 213, "start_aa": "Thr", "end_pos": 213, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr213", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 59, "start_aa": "Thr", "end_pos": 59, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr59", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 89, "start_aa": "Thr", "end_pos": 89, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr89", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H807", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H807" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H807", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H807" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770560", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770560", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "D-glucose:sodium symporter activity", "id": "GO:0005412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005412", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H807", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H807" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H807", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H807" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H807", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H807" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H807", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H807" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H807", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H807" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", 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"uniprot_ac": "A0A9J7H810", "uniprot_id": "A0A9J7H810_CRIGR", "mass": { "chemical_mass": 52058.0, "monoisotopic_mass": 52058.0 }, "refseq": { "ac": "XP_035305617", "name": "60S ribosomal protein L5-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305617" }, "gene_names": [ { "name": "LOC100757709", "type": "recommended", "evidence": [ { "id": "A0A9J7H810", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H810" } ] }, { "name": "LOC100757709", "type": "synonym", "evidence": [ { "id": "XP_035305617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305617" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein uL18", "type": "recommended", "evidence": [ { "id": "A0A9J7H810", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H810/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L5-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305617" } ] }, { "name": "60S ribosomal protein L5", "type": "synonym", "evidence": [ { "id": "A0A9J7H810", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H810/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 37% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305617", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305617" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H810", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H810" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100757709", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H810", "locus": {} } ], "crossref": [ { "id": "A0A9J7H810", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H810", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00432", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00432", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757709", "url": "https://www.ncbi.nlm.nih.gov/gene/100757709", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757709", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757709", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H810", "url": "https://www.orthodb.org/?gene=A0A9J7H810", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23410", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23410", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23410:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23410:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14204", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14204", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305617", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305617", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H810", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H810", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H810-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H810-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLKTKKGIAILLFWIKETDITVPVQSPWNIPLLPVKKTGASGSHVSDSSRETGVRCLGPEICIHQPPIGRDSLVKKEWTAQAHRLMQDTRGKDHSPRNNQHDSGNWPSSGYSSVLHTIFGVARTKCRRACRSVWSCSCGCLFHRIGFVKIVKNKAYFKRYQVRFRRQREGKTDSYARKRLVIQDKNKYNTPKYRKIVRVTERSSARLPVPIIEGDMIVCTSYEHELPKYGVKVGLTNYTAAYCTSLLLARRLFNRFGMGKIYEGQVEVTGDEYNVESIDSQPGAFTCYLYAGLAQTTTGNKVFGGLKGAVDGGLSIPHSTKRFPGYDSESKEINAEVHRKHIMGQNAADHMGYLIEEEEEEDKKQFSQYIKNNVTPDMEEMYKKAHAAIPENPVYEKKPKRKVKKKRWNRPKMSLVQKKDRVAQKKASLMAHLKALGYKEEIMLKKSRHKEVIKL", "length": 456, "header": "tr|A0A9J7H810-1|A0A9J7H810_CRIGR Isoform 1 of Large ribosomal subunit protein uL18 OS=Cricetulus griseus OX=10029 GN=LOC100757709 PE=3 SV=1 CANONICAL=A0A9J7H810-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H810-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H810/entry#A0A9J7H810-1", "sequence": { "sequence": "MTLKTKKGIAILLFWIKETDITVPVQSPWNIPLLPVKKTGASGSHVSDSSRETGVRCLGPEICIHQPPIGRDSLVKKEWTAQAHRLMQDTRGKDHSPRNNQHDSGNWPSSGYSSVLHTIFGVARTKCRRACRSVWSCSCGCLFHRIGFVKIVKNKAYFKRYQVRFRRQREGKTDSYARKRLVIQDKNKYNTPKYRKIVRVTERSSARLPVPIIEGDMIVCTSYEHELPKYGVKVGLTNYTAAYCTSLLLARRLFNRFGMGKIYEGQVEVTGDEYNVESIDSQPGAFTCYLYAGLAQTTTGNKVFGGLKGAVDGGLSIPHSTKRFPGYDSESKEINAEVHRKHIMGQNAADHMGYLIEEEEEEDKKQFSQYIKNNVTPDMEEMYKKAHAAIPENPVYEKKPKRKVKKKRWNRPKMSLVQKKDRVAQKKASLMAHLKALGYKEEIMLKKSRHKEVIKL", "length": 456, "header": "tr|A0A9J7H810-1|A0A9J7H810_CRIGR Isoform 1 of Large ribosomal subunit protein uL18 OS=Cricetulus griseus OX=10029 GN=LOC100757709 PE=3 SV=1 CANONICAL=A0A9J7H810-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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[ { "name": "MAU2 chromatid cohesion factor homolog", "type": "recommended", "evidence": [ { "id": "A0A9J7H827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H827/entry#names_and_taxonomy" } ] }, { "name": "Cohesin loading complex subunit SCC4 homolog", "type": "synonym", "evidence": [ { "id": "A0A9J7H827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H827/entry#names_and_taxonomy" } ] }, { "name": "MAU2 chromatid cohesion factor homolog", "type": "synonym", "evidence": [ { "id": "XP_035307351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307351" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 22% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307351", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307351" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H827", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H827" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC118237723", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H827", "locus": {} } ], "crossref": [ { "id": "A0A9J7H827", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H827", "database": "AlphaFoldDB", "categories": [] }, { "id": "118237723", "url": "https://www.ncbi.nlm.nih.gov/gene/118237723", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:118237723", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118237723", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H827", "url": "https://www.orthodb.org/?gene=A0A9J7H827", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10345", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10345", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307351", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307351", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H827", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H827", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H827-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H827-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRRHLRGGSRGCGALGLVGNVVLLRQSRPTLVGQRVSSPQRRRRPFVKPFSREPQTPRPRPSQRFRLSVEAACCCAGQDGGSGAAAAAQAAAAAQAAAAQAAQAEAAESWYLALLGFAEHFRTSSPPKIRLCVHCLQAVFPFKPPQRIEARTHLQLGSVLYHHTKNSEQARSHLEKAWLISQQIPQFEDVKFEAASLLSELYCQENSVDAAKPLLRKAIQISQQTPYWHCRLLFQLAQLHTLEKDLVSACDLLGVGAEYARVVGSEYTRALFLLSKGMVSQGWMGAAILQEGSHLARRPYCKKEGTWLLGVFSRTRALL", "length": 320, "header": "tr|A0A9J7H827-1|A0A9J7H827_CRIGR Isoform 1 of MAU2 chromatid cohesion factor homolog OS=Cricetulus griseus OX=10029 GN=LOC118237723 PE=3 SV=1 CANONICAL=A0A9J7H827-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H827-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H827/entry#A0A9J7H827-1", "sequence": { "sequence": "MLRRHLRGGSRGCGALGLVGNVVLLRQSRPTLVGQRVSSPQRRRRPFVKPFSREPQTPRPRPSQRFRLSVEAACCCAGQDGGSGAAAAAQAAAAAQAAAAQAAQAEAAESWYLALLGFAEHFRTSSPPKIRLCVHCLQAVFPFKPPQRIEARTHLQLGSVLYHHTKNSEQARSHLEKAWLISQQIPQFEDVKFEAASLLSELYCQENSVDAAKPLLRKAIQISQQTPYWHCRLLFQLAQLHTLEKDLVSACDLLGVGAEYARVVGSEYTRALFLLSKGMVSQGWMGAAILQEGSHLARRPYCKKEGTWLLGVFSRTRALL", "length": 320, "header": "tr|A0A9J7H827-1|A0A9J7H827_CRIGR Isoform 1 of MAU2 chromatid cohesion factor homolog OS=Cricetulus griseus OX=10029 GN=LOC118237723 PE=3 SV=1 CANONICAL=A0A9J7H827-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614393.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007646290", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646290" } ] }, { "annotation": "Functions as an ubiquitin ligase protein, and regulates Notch signaling. By promoting the ubiquitination and subsequent degradation of target proteins, it can block activation of the Notch signaling pathway, potentially acting as a tumor suppressor in human cancers.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J769", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J769#function" }, { "database": "UniProtKB", "id": "ARBA00094264", "url": "https://www.uniprot.org/uniprotkb/ARBA00094264#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H828", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H828" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dtx3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H828", "locus": {} } ], "crossref": [ { "id": "cd09633", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09633", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16711", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16711", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764385", "url": "https://www.ncbi.nlm.nih.gov/gene/100764385", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039399", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039399", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764385", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764385", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XAEHPNP", "url": "https://omabrowser.org/oma/group/XAEHPNP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H828", "url": "https://www.orthodb.org/?gene=A0A9J7H828", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J769", "url": "https://www.orthodb.org/?gene=A0A9J7J769", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12622", "url": 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"A0A9J7J769-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J769-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFVLSRMAACGGTCKNKVTVSKPVWDFLSKETPARLARLREEHRVSILIDGETSDIYVLQLSPQGPPPAPPNGLYLARKALKGLLKEAEKELKKAQRQGELMGCLALGGGGEHPELHRPGPPPLRAAPLLPPGARGLPPPPPPLPPPLPPRLREEAEEQESTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLVGNQPQNGRMLVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLCASSSSASPAPSPLSISTLGESSTPSAGSLLTGDHPPPSLCFHPSPHVLSCNKTKSLQILAYLGFGGSLLMGTGEGSEFGLY", "length": 405, "header": "tr|A0A9J7H828-1|A0A9J7H828_CRIGR Isoform 1 of E3 ubiquitin-protein ligase OS=Cricetulus griseus OX=10029 GN=Dtx3 PE=3 SV=1 CANONICAL=A0A9J7H828-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H828-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H828/entry#A0A9J7H828-1", "sequence": { "sequence": 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"MSFVLSRMAACGGTCKNKVTVSKPVWDFLSKETPARLARLREEHRVSILIDGETSDIYVLQLSPQGPPPAPPNGLYLARKALKGLLKEAEKELKKAQRQGELMGCLALGGGGEHPELHRPGPPPLRAAPLLPPGARGLPPPPPPLPPPLPPRLREEAEEQESTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLVGNQPQNGRMLVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFGYPDPTYLTRVQEELRAKGITDD", "length": 347, "header": "tr|A0A9J7J769-1|A0A9J7J769_CRIGR Computationally mapped isoform of E3 ubiquitin-protein ligase OS=Cricetulus griseus OX=10029 GN=Dtx3 PE=3 SV=1 CANONICAL=A0A9J7H828-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 347, "start_aa": "Thr", "end_pos": 347, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr347", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H828", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H828" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H828", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H828" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764385", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764385", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LDP4-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Dtx3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFVLSRMAACGGSCKNKVTVSKPVWDFLSKETPARLARLREEHRVSILIDGETSDIYVLQLSPQGPPPAPPNGLYLARKALKGLLKEAEKELKKAQRQGELMGCLALGGGGEHPELHRPGPPPLRAAPLLPPGARGLPPPPPPLPPPLPPRLREDAEEQETTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLVGNQPQNGRMLVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFGYPDPTYLTRVQEELRAKGITDD", "length": 347 }, "evidence": [ { "id": "A0A9J7H828", "url": "https://omabrowser.org/oma/group/A0A9J7H828/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80V91-1", "protein_name": "E3 ubiquitin-protein ligase DTX3", "gene_name": "Dtx3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFVLSRMAACGGSCKNKVTVSKPVWDFLSKETPARLARLREEHRVSILIDGETSDIYVLQLSPQGPPPAPPNGLYLARKALKGLLKEAEKELKKAQRQGELMGCLALGGGGEHPELHRPGPPPLRAAPLLPPGARGLPPPPPPLPPPLPPRLREDAEEQETTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLVGNQPQNGRMLVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFGYPDPTYLTRVQEELRAKGITDD", "length": 347 }, "evidence": [ { "id": "A0A9J7H828", "url": "https://omabrowser.org/oma/group/A0A9J7H828/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N9I9-1", "protein_name": "E3 ubiquitin-protein ligase DTX3", "gene_name": "DTX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"XP_035305644", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305644" } ] } ], "protein_names": [ { "name": "mitogen-activated protein kinase kinase kinase", "type": "recommended", "evidence": [ { "id": "A0A9J7H8E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.25", "type": "synonym", "evidence": [ { "id": "A0A9J7H8E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3/entry#names_and_taxonomy" } ] }, { "name": "mitogen-activated protein kinase kinase kinase 15 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305644", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305644" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305644", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305644" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Map3k15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3", "locus": {} } ], "crossref": [ { "id": "A0A9J7H8E3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H8E3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06624", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06624", "database": "CDD", "categories": [ "Protein Classification" ] 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13281", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13281", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20302", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20302", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305644", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305644", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H8E3", 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"MYFLDFSVLKIEYIVCLLKASSGNYYFIPYTVTPCADYFCCESDAQRRASEYMQPNWDTILGPLCMPLVDKFTSLLKDIRVTSCAYYKETLLNDIRKAREKYQGDELAKELTRIKFRMDNIEVLTSDIIINLLLSYRDIQDYDAMVKLVETLKMLPTCDLADQHNIKFHYAFALNRKKEVGSLFLQIRDVIHEQGRTPMEGIWRNSTGDREKALQVMLQVLQSCDHPAPDMFCLCGRIYKDIFLDSGCEEDASRDSAIEWYRKGFELQSSLYSGINLAVLLIVAGQQFETSMELRKIGVRLNSLLGRKGSLEKMNNYWDVGQFFTVSMLASDVGKAVQAAERLFKLKPPVWYLRSLVQNLLLIQRFKKPITEYSPRQERLNFWLDIIFEATNEVTNGLRFPVLVIEPTKVYQPSYVSINNEAEERTVSLWHVSPTEMKQIHEWNFTPSSIKGISLSKFDERCCFLYVHDNSDDFQIYFSTEDQCNRFCSLVKEMLNNGVGSTVELEGEADGDTLEYEYDHDVNGERIVLGKGSYGIVYAGRDLSNQVRIAIKEIPERDIRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCTETFAGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSRPPFHELGEPQAAMFKVGMFKIHPEIPESLSTEARAFILSCFEPDPHKRATAANLLQEGFLRQVNKGKKNRIAFKPSESVRSATGTLALPSAGELMCSSSSEHGSVSPDSDAQHDAFFEKTQVPKHQLSHLLSVPDESAALEDRSTALSPEERDPGLFLLRKDSERRAILYRILWEEQNQVASNLQECVVQSSEELLLSVGHIKQIIGILRDFIRSPEHRVMAATISKLKVDLDFDSSSINQIHLILFGFQDAVNRILRNHLIRPHWMFAMDNIIRRAVQAAVAILIPELQAHFEPASETEGVDKDTEVEGDYPLVDLLGQVHMTPRGTRPGSVGIQEGQPNQQDPTLQLSKLRQENNRLWEHLVQKEREYQNLLRLTLEQKTQELHHLQLQYKSSGGTENPVPPDEVGTDRELIDWLQLQGADANTIEKIVEEDYTLSDILNDITKEDLRCLRLRGGVLCRLWHAVSQHRRQMQESSH", "length": 1197, "header": "tr|A0A9J7H8E3-1|A0A9J7H8E3_CRIGR Isoform 1 of mitogen-activated protein kinase kinase kinase OS=Cricetulus griseus OX=10029 GN=Map3k15 PE=3 SV=1 CANONICAL=A0A9J7H8E3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H8E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3/entry#A0A9J7H8E3-1", "sequence": { "sequence": "MYFLDFSVLKIEYIVCLLKASSGNYYFIPYTVTPCADYFCCESDAQRRASEYMQPNWDTILGPLCMPLVDKFTSLLKDIRVTSCAYYKETLLNDIRKAREKYQGDELAKELTRIKFRMDNIEVLTSDIIINLLLSYRDIQDYDAMVKLVETLKMLPTCDLADQHNIKFHYAFALNRKKEVGSLFLQIRDVIHEQGRTPMEGIWRNSTGDREKALQVMLQVLQSCDHPAPDMFCLCGRIYKDIFLDSGCEEDASRDSAIEWYRKGFELQSSLYSGINLAVLLIVAGQQFETSMELRKIGVRLNSLLGRKGSLEKMNNYWDVGQFFTVSMLASDVGKAVQAAERLFKLKPPVWYLRSLVQNLLLIQRFKKPITEYSPRQERLNFWLDIIFEATNEVTNGLRFPVLVIEPTKVYQPSYVSINNEAEERTVSLWHVSPTEMKQIHEWNFTPSSIKGISLSKFDERCCFLYVHDNSDDFQIYFSTEDQCNRFCSLVKEMLNNGVGSTVELEGEADGDTLEYEYDHDVNGERIVLGKGSYGIVYAGRDLSNQVRIAIKEIPERDIRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCTETFAGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSRPPFHELGEPQAAMFKVGMFKIHPEIPESLSTEARAFILSCFEPDPHKRATAANLLQEGFLRQVNKGKKNRIAFKPSESVRSATGTLALPSAGELMCSSSSEHGSVSPDSDAQHDAFFEKTQVPKHQLSHLLSVPDESAALEDRSTALSPEERDPGLFLLRKDSERRAILYRILWEEQNQVASNLQECVVQSSEELLLSVGHIKQIIGILRDFIRSPEHRVMAATISKLKVDLDFDSSSINQIHLILFGFQDAVNRILRNHLIRPHWMFAMDNIIRRAVQAAVAILIPELQAHFEPASETEGVDKDTEVEGDYPLVDLLGQVHMTPRGTRPGSVGIQEGQPNQQDPTLQLSKLRQENNRLWEHLVQKEREYQNLLRLTLEQKTQELHHLQLQYKSSGGTENPVPPDEVGTDRELIDWLQLQGADANTIEKIVEEDYTLSDILNDITKEDLRCLRLRGGVLCRLWHAVSQHRRQMQESSH", "length": 1197, "header": "tr|A0A9J7H8E3-1|A0A9J7H8E3_CRIGR Isoform 1 of mitogen-activated protein kinase kinase kinase OS=Cricetulus griseus OX=10029 GN=Map3k15 PE=3 SV=1 CANONICAL=A0A9J7H8E3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 33, "start_aa": "Thr", "end_pos": 33, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr33", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751831", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751831", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3" } ], "pmid": "" }, { "name": "MAP kinase kinase kinase activity", "id": "GO:0004709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004709", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to stress", "id": "GO:0033554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033554", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + 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"url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3HX91-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", "A0A8C2QND0-1", "G3HXQ8-1", "A0A8C2M0A2-1", "A0A9J7K2S5-1", 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"G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] } ] }, { "uniprot_ac": "A0A8C2M3Y9", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", 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"url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] } ] }, { "uniprot_ac": "A0A8C2N185", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] } ] }, { "uniprot_ac": "A0A8C2N210", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": 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] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", 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H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] } ] }, { "uniprot_ac": "A0A9J7G5N9", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] } ] }, { "uniprot_ac": "A0A9J7G8N4", "gene_name": "Sgk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] } ] }, { "uniprot_ac": "A0A9J7G969", "gene_name": "LOC100754771", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] } ] }, { "uniprot_ac": "A0A9J7GES8", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": 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"ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] } ] }, { "uniprot_ac": "A0A9J7GQ42", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] } ] }, { "uniprot_ac": "A0A9J7GQY0", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] } ] }, { "uniprot_ac": "A0A9J7GR05", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] } ] }, { "uniprot_ac": "A0A9J7GR29", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": 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] }, { "uniprot_ac": "A0A9J7GT89", "gene_name": "LOC100774420", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] } ] }, { "uniprot_ac": "A0A9J7GTU0", "gene_name": "LOC100757707", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTU0" } ] } ] }, { "uniprot_ac": "A0A9J7GVC9", "gene_name": "LOC100759146", 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] } ] }, { "uniprot_ac": "A0A9J7GZH5", "gene_name": "Ripk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GZH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GZH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZH5" } ] } ] }, { "uniprot_ac": "A0A9J7H0E7", "gene_name": "Ksr2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H0E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0E7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H0E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0E7" } ] } ] }, { "uniprot_ac": "A0A9J7H0W8", "gene_name": "Dapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H0W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0W8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H0W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0W8" } ] } ] }, { "uniprot_ac": "A0A9J7H1I4", "gene_name": "LOC100764243", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H1I4", "database": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H2T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2T6" } ] } ] }, { "uniprot_ac": "A0A9J7H3E2", "gene_name": "LOC113836728", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "A0A9J7H3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E2" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "A0A9J7H3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E2" } ] } ] }, { "uniprot_ac": "A0A9J7H3L8", "gene_name": "Csnk2a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H503", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H503" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H503", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H503" } ] } ] }, { "uniprot_ac": "A0A9J7H540", "gene_name": "LOC113837157", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540" } ] } ] }, { "uniprot_ac": "A0A9J7H5D8", "gene_name": "Nek8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H5D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H5D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5D8" } ] } ] }, { "uniprot_ac": "A0A9J7H6V8", "gene_name": "Sbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H6V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H6V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8" } ] } ] }, { "uniprot_ac": "A0A9J7H7J5", "gene_name": "Prkacb", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H7J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J5" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7H7J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J5" } ] } ] }, { "uniprot_ac": "A0A9J7H7W6", "gene_name": "LOC113837158", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H7W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H7W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6" } ] } ] }, { "uniprot_ac": "A0A9J7H8E3", "gene_name": "Map3k15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7H8E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3" } ] } ] }, { "uniprot_ac": "A0A9J7H8L4", "gene_name": "Irak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8L4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H8L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8L4" } ] } ] }, { "uniprot_ac": "A0A9J7H8U3", "gene_name": "Wnk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H8U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U3" } ] } ] }, { "uniprot_ac": "A0A9J7H8W5", "gene_name": "Nrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H8W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8W5" } ] } ] }, { "uniprot_ac": "A0A9J7H8W9", "gene_name": "LOC100767231", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8W9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H8W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8W9" } ] } ] }, { "uniprot_ac": "A0A9J7H949", "gene_name": "LOC100750729", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H949" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H949" } ] } ] }, { "uniprot_ac": "A0A9J7HEQ9", "gene_name": "LOC113838165", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ] } ] }, { "uniprot_ac": "A0A9J7J1N3", "gene_name": "Limk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J1N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J1N3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7J1N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J1N3" } ] } ] }, { "uniprot_ac": "A0A9J7J5Z8", "gene_name": "Camk2g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7J5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8" } ] } ] }, { "uniprot_ac": "A0A9J7J6E9", "gene_name": "Vrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J6E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7J6E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6E9" } ] } ] }, { "uniprot_ac": "A0A9J7J6H1", "gene_name": "LOC100752268", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J6H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6H1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7J6H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6H1" } ] } ] }, { "uniprot_ac": "A0A9J7J728", "gene_name": "LOC113832236", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J728", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J728" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7J728", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J728" } ] } ] }, { "uniprot_ac": "A0A9J7JA07", "gene_name": "LOC100750629", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA07" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA07" } ] } ] }, { "uniprot_ac": "A0A9J7JAB2", "gene_name": "Stk24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAB2" } ] } ] }, { "uniprot_ac": "A0A9J7JAM4", "gene_name": "Sik1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JAM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAM4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JAM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAM4" } ] } ] }, { "uniprot_ac": "A0A9J7JB60", "gene_name": "Dclk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JB60" } ] } ] }, { "uniprot_ac": "A0A9J7JBH0", "gene_name": "Srpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JBH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JBH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH0" } ] } ] }, { "uniprot_ac": "A0A9J7JDU1", "gene_name": "Cdc42bpg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JDU1", "database": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGQ1" } ] } ] }, { "uniprot_ac": "A0A9J7JGR2", "gene_name": "Rock1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JGR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A9J7JGR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR2" } ] } ] }, { "uniprot_ac": "A0A9J7JHJ2", "gene_name": "Mast2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JQZ1", "gene_name": "Wnk1", "activity": [ { "ec_number": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] } ] }, { "uniprot_ac": "G3IN30", "gene_name": "Plk1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] } ] }, { "uniprot_ac": "O55076", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] } ] }, { "uniprot_ac": "P25321", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P25321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25321" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P25321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25321" } ] } ] }, { "uniprot_ac": "P50310", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "P50310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50310" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P50310", "database": "UniProtKB", "url": 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8F0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769749", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769749", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8F0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8F0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1144, "end_pos": 1146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1288, "end_pos": 1290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1426, "end_pos": 1428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1144, "end_pos": 1146 }, { "start_pos": 1288, "end_pos": 1290 }, { "start_pos": 1426, "end_pos": 1428 }, { "start_pos": 290, "end_pos": 292 }, { "start_pos": 350, "end_pos": 352 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H8G1-1", "uniprot_ac": "A0A9J7H8G1", "uniprot_id": "A0A9J7H8G1_CRIGR", "mass": { "chemical_mass": 111632.0, "monoisotopic_mass": 111632.0 }, "refseq": { "ac": "XP_027285880", "name": "liprin-beta-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285880" }, "gene_names": [ { "name": "Ppfibp1", "type": "recommended", "evidence": [ { "id": "A0A9J7H8G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1" } ] }, { "name": "Ppfibp1", "type": "synonym", "evidence": [ { "id": "XP_027285880", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285880" } ] } ], "protein_names": [ { "name": "Liprin-beta-1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7H8G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1/entry#names_and_taxonomy" } ] }, { "name": "liprin-beta-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027285880", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285880" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027285880", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285880" } ] }, { "annotation": "May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JRD1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRD1#function" }, { "database": "UniProtKB", "id": "ARBA00060046", "url": "https://www.uniprot.org/uniprotkb/ARBA00060046#function" }, { "database": "UniProtKB", "id": "A0A9J7JXK1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXK1#function" }, { "database": "UniProtKB", "id": "A0A9J7JZA5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZA5#function" }, { "database": "UniProtKB", "id": "A0A9J7K0U1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0U1#function" }, { "database": "UniProtKB", "id": "A0A9J7H8G1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1#function" }, { "database": "UniProtKB", "id": "A0A9J7GHK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK3#function" }, { "database": "UniProtKB", "id": "A0A9J7GHL1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHL1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ppfibp1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1", "locus": {} } ], "crossref": [ { "id": "cd09563", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09563", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09566", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09566", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09569", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09569", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754722", "url": "https://www.ncbi.nlm.nih.gov/gene/100754722", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754722", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754722", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H8G1", "url": "https://www.orthodb.org/?gene=A0A9J7H8G1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027285880", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285880", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GHK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GHK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GHL1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GHL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8G1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRD1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXK1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZA5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K0U1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0U1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K0U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0U1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLELVAEVSNLKLKLTAVEKDRLDYEDRFRDTEGLIQEISDLRLKVSEMDSERLQYEKKLKSTKDELTSLKEQLEEKECEVKRLQERVLCRTKGDGMEILDRDENVKKKLKEKNIEVQKMKKAVESLMAANEEKDQKIEDLRQCLNRYKKMQDPAILAQGQDGECEGLFHSSSISTLLDAQGFSDLERSTSSTPGMGSPSRDPFNTSAPEELQASAPSLLPPSMGVETSEKSKLPTKPEASFEDTDGKAILGAAAEAPLCDGLSTSSLQKSSSLGNLKRETSDGLEKESIQKPAEDKAPTDSCTFGTLPPKVPGHDVSMDDNPFGTRKARSSFGRGFFKIKSNKRTASAPNLDRKRSASAPTLAETEKETAEHLDLAGTSRPKGSQGTSPFQMSPPSPDSKKKSRGIMRLFGRLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDTPFAKWTKEQVCSWLAEQGLGSYLSSGKHWIISGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNYGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENGVTASEVQQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLTFSNFGNLRKKKHEDGEEYVCPMDLGQVSGSSSQKGFRPGLDMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV", "length": 997, "header": "tr|A0A9J7H8G1-1|A0A9J7H8G1_CRIGR Isoform 1 of Liprin-beta-1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ppfibp1 PE=3 SV=1 CANONICAL=A0A9J7H8G1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GHK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1/entry#A0A9J7GHK3-1", "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLELVAEVSNLKLKLTAVEKDRLDYEDRFRDTEGLIQEISDLRLKVSEMDSERLQYEKKLKSTKDELTSLKEQLEEKECEVKRLQERVLCRTKGDGMEILDRDENVKKKLKEKNIEVQKMKKAVESLMAANEEKDQKIEDLRQCLNRYKKMQDPAILAQGQDGECEGLFHSSSISTLLDAQGFSDLERSTSSTPGMGSPSRDPFNTSAPEELQASAPSLLPPSMGVETSEKSKLPTKPEASFEDTDGKAILGAAAEAPLCDGLSTSSLQKSSSLGNLKRETSDGLDKAPTDSCTFGTLPPKVPGHDVSMDDNPFGTRKARSSFGRGFFKIKSNKRTASAPNLDRKRSASAPTLAETEKETAEHLDLAGTSRPKGSQGTSPFQMSPPSPDSKKKSRGIMRLFGRLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDTPFAKWTKEQVCSWLAEQGLGSYLSSGKHWIISGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNYGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENGVTASEVQQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLTFSNFGNLRKKKHEDGEEYVCPMDLGQVSGSSSQKGFRPGLDMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV", "length": 987, "header": "tr|A0A9J7GHK3-1|A0A9J7GHK3_CRIGR Computationally mapped isoform of Liprin-beta-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ppfibp1 PE=3 SV=1 CANONICAL=A0A9J7H8G1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GHL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1/entry#A0A9J7GHL1-1", "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLELVAEVSNLKLKLTAVEKDRLDYEDRFRDTEGLIQEISDLRLKVSEMDSERLQYEKKLKSTKDELTSLKEQLEEKECEVKRLQERVLCRTKGDGMEILDRDIEVQKMKKAVESLMAANEEKDQKIEDLRQCLNRYKKMQDPAILAQGQDGECEGLFHSSSISTLLDAQGFSDLERSTSSTPGMGSPSRDPFNTSAPEELQASAPSLLPPSMGVETSEKSKLPTKPEASFEDTDGKAILGAAAEAPLCDGLSTSSLQKSSSLGNLKRETSDGLEKESIQKPAEDKAPTDSCTFGTLPPKVPGHDVSMDDNPFGTRKARSSFGRGFFKIKSNKRTASAPNLDRKRSASAPTLAETEKETAEHLDLAGTSRPKGSQGTSPFQMSPPSPDSKKKSRGIMRLFGRLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDTPFAKWTKEQVCSWLAEQGLGSYLSSGKHWIISGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNYGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENGVTASEVQQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLTFSNFGNLRKKKHEDGEEYVCPMDLGQVSGSSSQKGFRPGLDMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV", "length": 986, "header": "tr|A0A9J7GHL1-1|A0A9J7GHL1_CRIGR Computationally mapped isoform of Liprin-beta-1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Ppfibp1 PE=3 SV=1 CANONICAL=A0A9J7H8G1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H8G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1/entry#A0A9J7H8G1-1", "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLELVAEVSNLKLKLTAVEKDRLDYEDRFRDTEGLIQEISDLRLKVSEMDSERLQYEKKLKSTKDELTSLKEQLEEKECEVKRLQERVLCRTKGDGMEILDRDENVKKKLKEKNIEVQKMKKAVESLMAANEEKDQKIEDLRQCLNRYKKMQDPAILAQGQDGECEGLFHSSSISTLLDAQGFSDLERSTSSTPGMGSPSRDPFNTSAPEELQASAPSLLPPSMGVETSEKSKLPTKPEASFEDTDGKAILGAAAEAPLCDGLSTSSLQKSSSLGNLKRETSDGLEKESIQKPAEDKAPTDSCTFGTLPPKVPGHDVSMDDNPFGTRKARSSFGRGFFKIKSNKRTASAPNLDRKRSASAPTLAETEKETAEHLDLAGTSRPKGSQGTSPFQMSPPSPDSKKKSRGIMRLFGRLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDTPFAKWTKEQVCSWLAEQGLGSYLSSGKHWIISGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNYGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENGVTASEVQQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLTFSNFGNLRKKKHEDGEEYVCPMDLGQVSGSSSQKGFRPGLDMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV", "length": 997, "header": "tr|A0A9J7H8G1-1|A0A9J7H8G1_CRIGR Isoform 1 of Liprin-beta-1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ppfibp1 PE=3 SV=1 CANONICAL=A0A9J7H8G1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JRD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1/entry#A0A9J7JRD1-1", "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLELVAEVSNLKLKLTAVEKDRLDYEDRFRDTEGLIQEISDLRLKVSEMDSERLQYEKKLKSTKDELTSLKEQLEEKECEVKRLQERVLCRTKGDGMEILDRDENVKKKLKEKNIEVQKMKKAVESLMAANEEKDQKIEDLRQCLNRYKKMQDPAILAQGQDGECEGLFHSSSISTLLDAQGFSDLERSTSSTPGMGSPSRDPFNTSAPEELQASAPSLLPPSMGVETSEKSKLPTKPEASFEDTDGKAILGAAAEAPLCDGLSTSSLQKSSSLGNLKRETSDGLDKAPTDSCTFGTLPPKVPGHDVSMDDNPFGTRKARSSFGRGFFKIKSNKRTASAPNLAETEKETAEHLDLAGTSRPKGSQGTSPFQMSPPSPDSKKKSRGIMRLFGRLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDTPFAKWTKEQVCSWLAEQGLGSYLSSGKHWIISGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNYGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENGVTASEVQQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLTFSNFGNLRKKKHEDGEEYVCPMDLGQVSGSSSQKGFRPGLDMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV", "length": 976, "header": "tr|A0A9J7JRD1-1|A0A9J7H8G1_CRIGR Computationally mapped isoform of Liprin-beta-1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ppfibp1 PE=3 SV=1 CANONICAL=A0A9J7H8G1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JXK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1/entry#A0A9J7JXK1-1", "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLELVAEVSNLKLKLTAVEKDRLDYEDRFRDTEGLIQEISDLRLKVSEMDSERLQYEKKLKSTKDELTSLKEQLEEKECEVKRLQERVLCRTKGDGMEILDRDENVKKKLKEKNIEVQKMKKAVESLMAANEEKDQKIEDLRQCLNRYKKMQDPAILAQGQDGECEGLFHSSSISTLLDAQGFSDLERSTSSTPGMGSPSRDPFNTSAPEELQASAPSLLPPSMGVETSEKSKLPTKPEASFEDTDGKAILGAAAEAPLCDGLSTSSLQKSSSLGNLKRETSDGLEKESIQKPAEDKAPTDSCTFGTLPPKVPGHDVSMDDNPFGTRKARSSFGRGFFKIKSNKRTASAPNLAETEKETAEHLDLAGTSRPKGSQGTSPFQMSPPSPDSKKKSRGIMRLFGRLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDTPFAKWTKEQVCSWLAEQGLGSYLSSGKHWIISGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNYGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENGVTASEVQQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLTFSNFGNLRKKKHEDGEEYVCPMDLGQVSGSSSQKGFRPGLDMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV", "length": 986, "header": "tr|A0A9J7JXK1-1|A0A9J7H8G1_CRIGR Computationally mapped isoform of Liprin-beta-1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ppfibp1 PE=3 SV=1 CANONICAL=A0A9J7H8G1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JZA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1/entry#A0A9J7JZA5-1", "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLELVAEVSNLKLKLTAVEKDRLDYEDRFRDTEGLIQEISDLRLKVSEMDSERLQYEKKLKSTKDELTSLKEQLEEKECEVKRLQERVLCRTKGDGMEILDRDIEVQKMKKAVESLMAANEEKDQKIEDLRQCLNRYKKMQDPAILAQGQDGECEGLFHSSSISTLLDAQGFSDLERSTSSTPGMGSPSRDPFNTSAPEELQASAPSLLPPSMGVETSEKSKLPTKPEASFEDTDGKAILGAAAEAPLCDGLSTSSLQKSSSLGNLKRETSDGLDKAPTDSCTFGTLPPKVPGHDVSMDDNPFGTRKARSSFGRGFFKIKSNKRTASAPNLAETEKETAEHLDLAGTSRPKGSQGTSPFQMSPPSPDSKKKSRGIMRLFGRLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDTPFAKWTKEQVCSWLAEQGLGSYLSSGKHWIISGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNYGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENGVTASEVQQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLTFSNFGNLRKKKHEDGEEYVCPMDLGQVSGSSSQKGFRPGLDMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV", "length": 965, "header": "tr|A0A9J7JZA5-1|A0A9J7H8G1_CRIGR Computationally mapped isoform of Liprin-beta-1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ppfibp1 PE=3 SV=1 CANONICAL=A0A9J7H8G1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K0U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1/entry#A0A9J7K0U1-1", "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLELVAEVSNLKLKLTAVEKDRLDYEDRFRDTEGLIQEISDLRLKVSEMDSERLQYEKKLKSTKDELTSLKEQLEEKECEVKRLQERVLCRTKGDGMEILDRDIEVQKMKKAVESLMAANEEKDQKIEDLRQCLNRYKKMQDPAILAQGQDGECEGLFHSSSISTLLDAQGFSDLERSTSSTPGMGSPSRDPFNTSAPEELQASAPSLLPPSMGVETSEKSKLPTKPEASFEDTDGKAILGAAAEAPLCDGLSTSSLQKSSSLGNLKRETSDGLEKESIQKPAEDKAPTDSCTFGTLPPKVPGHDVSMDDNPFGTRKARSSFGRGFFKIKSNKRTASAPNLAETEKETAEHLDLAGTSRPKGSQGTSPFQMSPPSPDSKKKSRGIMRLFGRLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDTPFAKWTKEQVCSWLAEQGLGSYLSSGKHWIISGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNYGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENGVTASEVQQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLTFSNFGNLRKKKHEDGEEYVCPMDLGQVSGSSSQKGFRPGLDMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV", "length": 975, "header": "tr|A0A9J7K0U1-1|A0A9J7H8G1_CRIGR Computationally mapped isoform of Liprin-beta-1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ppfibp1 PE=3 SV=1 CANONICAL=A0A9J7H8G1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 361, "start_aa": "Thr", "end_pos": 361, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr361", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JRD1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRD1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JRD1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRD1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754722", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754722", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neuromuscular junction development", "id": "GO:0007528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007528", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 844, "end_pos": 846, "annotation": "n_glycosylation_sequon" }, { "start_pos": 967, "end_pos": 969, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H8G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G1" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 633, "end_pos": 697, "start_aa": "Trp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 361 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, "end_pos": 151 }, { "start_pos": 373, "end_pos": 375 }, { "start_pos": 844, "end_pos": 846 }, { "start_pos": 967, "end_pos": 969 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H8G9-1", "uniprot_ac": "A0A9J7H8G9", "uniprot_id": "A0A9J7H8G9_CRIGR", "mass": { "chemical_mass": 176412.0, "monoisotopic_mass": 176412.0 }, "refseq": { "ac": "XP_035307003", "name": "leucine-rich repeat-containing protein 7 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307003" }, "gene_names": [ { "name": "Lrrc7", "type": "recommended", "evidence": [ { "id": "A0A9J7H8G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9" } ] }, { "name": "Lrrc7", "type": "synonym", "evidence": [ { "id": "XP_035307003", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307003" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 7 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7H8G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 7 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035307003", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307003" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307003", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307003" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lrrc7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9", "locus": {} } ], "crossref": [ { "id": "cd06749", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06749", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774869", "url": "https://www.ncbi.nlm.nih.gov/gene/100774869", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774869", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774869", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H8G9", "url": "https://www.orthodb.org/?gene=A0A9J7H8G9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23119:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23119:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307003", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307003", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H8G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCL2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESLMRGRNPPQYQRSPCKEARAALRKRPEEELQCLEMTTKRKLIGRLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSSLPTSIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFSELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKALIPLQTEAHPETKQRVLTNYMFPQQPRGDEDFQSDSDSFNPTLWEEQRQQRMTVAFEFEDKKEDDESAGKVKALSCQAPWDRGQRGITLQPARLSGDCCTPWARCDQQIQDMPVPQSDPQLAWGCISGLQQDRSMCAPLPVAAQSTTLPSLSGRQVEINLKRYPTPYPEDLKNMVKSVQNLVGKPSHGVRVENSNPTANTEQTVKEKFEHKWPVAPKEITVEDSFVHPANEMRIGELHPSLAETPLYPPKLVLLGKDKKESTDESEVDKTHCLNNSVSSGTYSDYSPSQASSGSSNTRVKVGSLQTTAKDTVHNSLWGNRIAPPFPQPLDAKPLLSQREAVPPGNLPQRPDRLPMSDAFPDNWTDGSHYDNTGFVSEEATAENANNNPLLSAKARSIPAHGRRPLIRQDRIVGVPLELEQSTHRHTPETEVPPSNPWQNWTRTPSPFEDRTAFPSKLETTPTTSPLPERKDHMKEPTETPGPFSPGVPWEYHDPTPNRSLGNVFSQIHCRPDSSKGVIAISKSTERLSPLMKDIKSNKFKKSQSIDEIDIGTYKVYNIPLENYASGSDHLGSHERPDKLLGPEHGMSSMSRSQSVPMLDDEMLMYGSSKGPPQQKASMTKKVYQFDQSFNPQGAVEVKAEKRIPPPFAHNSEYVQQPSKNIAKDLVSPRAYRGYPPMEQMLSFSQPSVNEDAIMNAQFASQGPRAGFLRRADSLASSTEMAMFRRVSEPHELPPGDRYGRAAYRGGLEGQSSISMTDPQFLKRNGRYEDEHPSYQEVKAQGGNFPAKNLTQRRPLSARSYSTESYGASQTRPVSARPTMAALLEKIPSDYNLGNYGDKPSDNSDVKTRPTPVKGEESCGKMPADWRQQLLRHIEARRLDRNAAYKHNTVNLGMLPYGGISAMHADRSMTLNLQTKSKFDLQDLPLQKTPSQQSNILDNGQEDVSPSGQWNPYPLGRRDVPPDTIAKKAGSHIQTLMGSQSLQHRSREQQPYEGNINKVTIQQFQSPLPIQIPSSQATRGPQPGRCLIQTKGQRSMDGYPEQFCVRIEKNPGLGFSISGGISGQGNPFKPSDKGIFVTRVQPDGPASNLLQPGDKILQANGHSFVHMEHEKAVLLLKSFQNTVDLVIQRELTV", "length": 1574, "header": "tr|A0A9J7H8G9-1|A0A9J7H8G9_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 7 isoform X2 OS=Cricetulus griseus OX=10029 GN=Lrrc7 PE=3 SV=1 CANONICAL=A0A9J7H8G9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H8G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9/entry#A0A9J7H8G9-1", "sequence": { "sequence": "MESLMRGRNPPQYQRSPCKEARAALRKRPEEELQCLEMTTKRKLIGRLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSSLPTSIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFSELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKALIPLQTEAHPETKQRVLTNYMFPQQPRGDEDFQSDSDSFNPTLWEEQRQQRMTVAFEFEDKKEDDESAGKVKALSCQAPWDRGQRGITLQPARLSGDCCTPWARCDQQIQDMPVPQSDPQLAWGCISGLQQDRSMCAPLPVAAQSTTLPSLSGRQVEINLKRYPTPYPEDLKNMVKSVQNLVGKPSHGVRVENSNPTANTEQTVKEKFEHKWPVAPKEITVEDSFVHPANEMRIGELHPSLAETPLYPPKLVLLGKDKKESTDESEVDKTHCLNNSVSSGTYSDYSPSQASSGSSNTRVKVGSLQTTAKDTVHNSLWGNRIAPPFPQPLDAKPLLSQREAVPPGNLPQRPDRLPMSDAFPDNWTDGSHYDNTGFVSEEATAENANNNPLLSAKARSIPAHGRRPLIRQDRIVGVPLELEQSTHRHTPETEVPPSNPWQNWTRTPSPFEDRTAFPSKLETTPTTSPLPERKDHMKEPTETPGPFSPGVPWEYHDPTPNRSLGNVFSQIHCRPDSSKGVIAISKSTERLSPLMKDIKSNKFKKSQSIDEIDIGTYKVYNIPLENYASGSDHLGSHERPDKLLGPEHGMSSMSRSQSVPMLDDEMLMYGSSKGPPQQKASMTKKVYQFDQSFNPQGAVEVKAEKRIPPPFAHNSEYVQQPSKNIAKDLVSPRAYRGYPPMEQMLSFSQPSVNEDAIMNAQFASQGPRAGFLRRADSLASSTEMAMFRRVSEPHELPPGDRYGRAAYRGGLEGQSSISMTDPQFLKRNGRYEDEHPSYQEVKAQGGNFPAKNLTQRRPLSARSYSTESYGASQTRPVSARPTMAALLEKIPSDYNLGNYGDKPSDNSDVKTRPTPVKGEESCGKMPADWRQQLLRHIEARRLDRNAAYKHNTVNLGMLPYGGISAMHADRSMTLNLQTKSKFDLQDLPLQKTPSQQSNILDNGQEDVSPSGQWNPYPLGRRDVPPDTIAKKAGSHIQTLMGSQSLQHRSREQQPYEGNINKVTIQQFQSPLPIQIPSSQATRGPQPGRCLIQTKGQRSMDGYPEQFCVRIEKNPGLGFSISGGISGQGNPFKPSDKGIFVTRVQPDGPASNLLQPGDKILQANGHSFVHMEHEKAVLLLKSFQNTVDLVIQRELTV", "length": 1574, "header": "tr|A0A9J7H8G9-1|A0A9J7H8G9_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 7 isoform X2 OS=Cricetulus griseus OX=10029 GN=Lrrc7 PE=3 SV=1 CANONICAL=A0A9J7H8G9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HCL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9/entry#A0A9J7HCL2-1", "sequence": { "sequence": "MESLMRGRNPPQYQRSPCKEARAALRKRPEEELQCLEMTTKRKLIGRLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSSLPTSIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFSELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKALIPLQTEAHPETKQRVLTNYMFPQQPRGDEDFQSDSDSFNPTLWEEQRQQRMTVAFEFEDKKEDDESAGKVKALSCQAPWDRGQRGITLQPARLSGDCCTPWARCDQQIQDMPVPQSDPQLAWGCISGLQQDRSMCAPLPVAAQSTTLPSLSGRQVEINLKRYPTPYPEDLKNMVKSVQNLVGKPSHGVRVENSNPTANTEQTVKEKFEHKWPVAPKEITVEDSFVHPANEMRIGELHPSLAETPLYPPKLVLLGKDKKESTDESEVDKTHCLNNSVSSGTYSDYSPSQASSGSSNTRVKVGSLQTTAKDTVHNSLWGNRIAPPFPQPLDAKPLLSQREAVPPGNLPQRPDRLPMSDAFPDNWTDGSHYDNTGFVSEEATAENANNNPLLSAKARSIPAHGRRPLIRQDRIVGVPLELEQSTHRHTPETEVPPSNPWQNWTRTPSPFEDRTAFPSKLETTPTTSPLPERKDHMKEPTETPGPFSPGVPWEYHDPTPNRSLGNVFSQIHCRPDSSKGVIAISKSTERLSPLMKDIKSNKFKKSQSIDEIDIGTYKVYNIPLENYASGSDHLGSHERPDKLLGPEHGMSSMSRSQSVPMLDDEMLMYGSSKGPPQQKASMTKKVYQFDQSFNPQGAVEVKAEKRIPPPFAHNSEYVQQPSKNIAKDLVSPRAYRGYPPMEQMLSFSQPSVNEDAIMNAQFASQGPRAGFLRRADSLASSTEMAMFRRVSEPHELPPGDRYGRAAYRGGLEGQSSISMTDPQFLKRNGRYEDEHPSYQEVKAQGGNFPAKNLTQRRPLSARSYSTESYGASQTRPVSARPTMAALLEKIPSDYNLGNYGDKPSDNSDVKTRPTPVKGEESCGKMPADWRQQLLRHIEARRLDRTPSQQSNILDNGQEDVSPSGQWNPYPLGRRDVPPDTIAKKAGSHIQTLMGSQSLQHRSREQQPYEGNINKVTIQQFQSPLPIQIPSSQATRGPQPGRCLIQTKGQRSMDGYPEQFCVRIEKNPGLGFSISGGISGQGNPFKPSDKGIFVTRVQPDGPASNLLQPGDKILQANGHSFVHMEHEKAVLLLKSFQNTVDLVIQRELTV", "length": 1527, "header": "tr|A0A9J7HCL2-1|A0A9J7HCL2_CRIGR Computationally mapped isoform of Leucine-rich repeat-containing protein 7 isoform X3 OS=Cricetulus griseus OX=10029 GN=Lrrc7 PE=3 SV=1 CANONICAL=A0A9J7H8G9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774869", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774869", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "neurotransmitter receptor transport, endosome to postsynaptic membrane", "id": "GO:0098887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9" } ], "pmid": "" }, { "name": "positive regulation of neuron projection development", "id": "GO:0010976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010976", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9" } ], "pmid": "" }, { "name": "receptor clustering", "id": "GO:0043113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043113", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9" } ], "pmid": "" }, { "name": "neurotransmitter receptor transport postsynaptic membrane to endosome", "id": "GO:0098968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098968", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9" } ], "pmid": "" }, { "name": "establishment or maintenance of epithelial cell apical/basal polarity", "id": "GO:0045197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045197", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9" } ], "pmid": "" }, { "name": "axon initial segment", "id": "GO:0043194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043194", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8G9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1230, "end_pos": 1232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 716, "end_pos": 718, "annotation": "n_glycosylation_sequon" }, { "start_pos": 804, "end_pos": 806, "annotation": "n_glycosylation_sequon" }, { "start_pos": 881, "end_pos": 883, "annotation": "n_glycosylation_sequon" }, { "start_pos": 939, "end_pos": 941, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H8G9", "database": "UniProtKB", "url": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H8H1-1", "uniprot_ac": "A0A9J7H8H1", "uniprot_id": "A0A9J7H8H1_CRIGR", "mass": { "chemical_mass": 138031.0, "monoisotopic_mass": 138031.0 }, "refseq": { "ac": "XP_035305160", "name": "zinc finger protein 420 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305160" }, "gene_names": [ { "name": "LOC103161318", "type": "recommended", "evidence": [ { "id": "A0A9J7H8H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8H1" } ] }, { "name": "LOC103161318", "type": "synonym", "evidence": [ { "id": "XP_035305160", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305160" } ] } ], "protein_names": [ { "name": "Zinc finger protein 420", "type": "recommended", "evidence": [ { "id": "A0A9J7H8H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8H1/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 420 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_035305160", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305160" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305160", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305160" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8H1#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A8C2LM35", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LM35#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8H1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC103161318", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8H1", "locus": {} } ], "crossref": [ { "id": "A0A9J7H8H1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H8H1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "103161318", "url": "https://www.ncbi.nlm.nih.gov/gene/103161318", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TFEYKEC", "url": "https://omabrowser.org/oma/group/TFEYKEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H8H1", "url": "https://www.orthodb.org/?gene=A0A9J7H8H1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226:SF412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226:SF412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305160", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305160", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LM35", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LM35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LM35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LM35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8H1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHVMTFRDVAIDFSPEEWECLTLEQRHLYRDVMLENYSHLVSVGLCIYQPHEFPVLAKEQDAFMDLGSEGRRFCPDIDPVWRKNKVLPKDSTRAGQLSQWEVLETDTNHSLEGLCPRADWEGKGQVPTPRETQEECFKQMTLTYEKLLMAFNQCPRLHIEEKASGFKSEKSFSFAEDPTQPQLIHTGEQSEDDKKCGKTFPPGSKLTRCRAVHPGKKAFQCEECGKAFSFRSSLTGHKRIHTGEKPFKCKECGKAFRFHSLLSVHVRIHTGEKSYECKECGKYFNYSSDLTRHHRIHTGEKPYQCRQCGKAFSCGSDLTRHERIHTGEKPYECNECGKAFIQQSHLIKHQRTHTGEKPYVCKECGKAFTCGSQLSQHKKIHTGDKLHKCKECKNSFSFALDHTQRQLIYIGEKFFEDKENGKTFFPDSKLAGFQTVHAGKKIYGCKECGKTFTLRSIVSSLKKIHNREKLFKCKDCEKAFRCPSDLSRHQKIHTGEKPYKCKECGKGFICRSDLGRHQRVHTGVKPYVCKECGKAFTRGAHLTQHQKSHSKKSHELSGGDKAFCCKECPKAFRYSSELTRHQRLHTGEKPYKCQDCWKAFASASDLARHQRIHTGERPYECSECGKAFIQQSHLIKHQRIHTGKKPYKCEECGKAFRRASHLTQHQSVHTGEKPYECEQCGKAFSRDSQLSLHQRLHTGEKPYACKECGKAFTQSSQLILHHRIHTGEKPYKCDECGKTFIRSSQLSRHQKVHTGEKPFECKACGKAFPQNSQLTLHQRLHTGEKLYDCKECRKVFTQLSQLLLHRRSHTGEKPYECKECGKAFICASQLSQHQKIHNGEKPYECKECGKAFIRGSLLMQHQRIHTGEKPYKCDDCGKAFIRGSQLTQHQRIHTNEKPYECKECGKTFSHGSQLTQHQRIHTGEKPYQCKECGKAFNRGSLLTRHQRIHTGEKPYDCKECGKNFSRGSELTQHERIHTGEKPYECKECGKSFIRSSQLTQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLHTGEKPYVCSECGKAFARGLLLIQHQRIHTGEKPYRCRECGKAFIRGSQLTQHQRTHTGEKPYECKECGKAFGHGSQLTLHQRIHTGEKPYECKECRKAFTQSSHLSRHQRIHTGEKPYQCKECEKAFTRGSQLMQHQRIHSSDKSVDCKECGIDFSHHSQFFI", "length": 1197, "header": "tr|A0A9J7H8H1-1|A0A9J7H8H1_CRIGR Isoform 1 of Zinc finger protein 420 OS=Cricetulus griseus OX=10029 GN=LOC103161318 PE=3 SV=1 CANONICAL=A0A9J7H8H1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LM35-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8H1/entry#A0A8C2LM35-1", "sequence": { "sequence": "MITYDKMSIFGPHTYLSQHPPGYSTEKPYKCEECGKAFRRASHLTQHQSVHTGEKPYECEQCGKAFSRDSQLSLHQRLHTGEKPYACKECGKAFTQSSQLILHHRIHTGEKPYKCDECGKTFIRSSQLSRHQKVHTGEKPFECKACGKAFPQNSQLTLHQRLHTGEKLYDCKECRKVFTQLSQLLLHRRSHTGEKPYECKECGKAFICASQLSQHQKIHNGEKPYECKECGKAFIRGSLLMQHQRIHTGEKPYKCDDCGKAFIRGSQLTQHQRIHTNEKPYECKECGKTFSHGSQLTQHQRIHTGEKPYQCKECGKAFNRGSLLTRHQRIHTGEKPYDCKECGKNFSRGSELTQHERIHTGEKPYECKECGKSFIRSSQLTQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLHTGEKPYVCSECGKAFARGLLLIQHQRIHTGEKPYRCRECGKAFIRGSQLTQHQRTHTGEKPYECKECGKAFGHGSQLTLHQRIHTGEKPYECKECRKAFTQSSHLSRHQRIHTGEKPYQCKECEKAFTRGSQLMQHQRIHSSDKSVDCKECGIDFSHHSQFFI", "length": 578, "header": "tr|A0A8C2LM35-1|A0A8C2LM35_CRIGR Computationally mapped isoform of Zinc finger protein 420 OS=Cricetulus griseus OX=10029 GN=LOC103161318 PE=3 SV=1 CANONICAL=A0A9J7H8H1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H8H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8H1/entry#A0A9J7H8H1-1", "sequence": { "sequence": "MAHVMTFRDVAIDFSPEEWECLTLEQRHLYRDVMLENYSHLVSVGLCIYQPHEFPVLAKEQDAFMDLGSEGRRFCPDIDPVWRKNKVLPKDSTRAGQLSQWEVLETDTNHSLEGLCPRADWEGKGQVPTPRETQEECFKQMTLTYEKLLMAFNQCPRLHIEEKASGFKSEKSFSFAEDPTQPQLIHTGEQSEDDKKCGKTFPPGSKLTRCRAVHPGKKAFQCEECGKAFSFRSSLTGHKRIHTGEKPFKCKECGKAFRFHSLLSVHVRIHTGEKSYECKECGKYFNYSSDLTRHHRIHTGEKPYQCRQCGKAFSCGSDLTRHERIHTGEKPYECNECGKAFIQQSHLIKHQRTHTGEKPYVCKECGKAFTCGSQLSQHKKIHTGDKLHKCKECKNSFSFALDHTQRQLIYIGEKFFEDKENGKTFFPDSKLAGFQTVHAGKKIYGCKECGKTFTLRSIVSSLKKIHNREKLFKCKDCEKAFRCPSDLSRHQKIHTGEKPYKCKECGKGFICRSDLGRHQRVHTGVKPYVCKECGKAFTRGAHLTQHQKSHSKKSHELSGGDKAFCCKECPKAFRYSSELTRHQRLHTGEKPYKCQDCWKAFASASDLARHQRIHTGERPYECSECGKAFIQQSHLIKHQRIHTGKKPYKCEECGKAFRRASHLTQHQSVHTGEKPYECEQCGKAFSRDSQLSLHQRLHTGEKPYACKECGKAFTQSSQLILHHRIHTGEKPYKCDECGKTFIRSSQLSRHQKVHTGEKPFECKACGKAFPQNSQLTLHQRLHTGEKLYDCKECRKVFTQLSQLLLHRRSHTGEKPYECKECGKAFICASQLSQHQKIHNGEKPYECKECGKAFIRGSLLMQHQRIHTGEKPYKCDDCGKAFIRGSQLTQHQRIHTNEKPYECKECGKTFSHGSQLTQHQRIHTGEKPYQCKECGKAFNRGSLLTRHQRIHTGEKPYDCKECGKNFSRGSELTQHERIHTGEKPYECKECGKSFIRSSQLTQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLHTGEKPYVCSECGKAFARGLLLIQHQRIHTGEKPYRCRECGKAFIRGSQLTQHQRTHTGEKPYECKECGKAFGHGSQLTLHQRIHTGEKPYECKECRKAFTQSSHLSRHQRIHTGEKPYQCKECEKAFTRGSQLMQHQRIHSSDKSVDCKECGIDFSHHSQFFI", "length": 1197, "header": "tr|A0A9J7H8H1-1|A0A9J7H8H1_CRIGR Isoform 1 of Zinc finger protein 420 OS=Cricetulus griseus OX=10029 GN=LOC103161318 PE=3 SV=1 CANONICAL=A0A9J7H8H1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8H1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8H1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9T6Q9-1", "protein_name": "Zinc finger protein 420", "gene_name": "ZNF420", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGRGLRPWRSLAWLPQGGRTRNRAGTPGTRSWALNCTLYRAPRGRKNDCCTVRSKLQDLPSRGANKLLSPKKDIYETGLSQWEMSARLENCDLENSSSRDHLEVKGTLEKQQENQAYFSQGMIIYDNMSIFNQHAYLSQHPRCHSTEKPYKCKECGKAFRRASHLTQHQSIHTGEKPYECKQCGKAFSRDSQLSLHQRLHTGEKPYACKECGKAFTQSSQLILHHRIHTGEKPYKCEECGKAFIRSSQLTRHQKVHTGEKPYECKECGKAFTQNSQLTLHQRLHTGEKLYECKECRKVFTQLSQLILHKRIHTGEKPYECKECGKAFICGSQLSQHQKIHNGEKPYECQECGKAFIRGSLLMQHQRIHTGEKPYKCEECGKAFIRGSQLTQHQRIHTNEKPYECKECGKTFSHGSQLTQHQRIHTGEKPYQCKECGKAFNRGSLLTRHQRIHTGEKPYECKECGKTFSRGSELTQHERIHTGEKPYECKECGKSFIRGSQLTQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLHTGEKPYVCNECGKAFARGLLLIQHQRIHTGEKPYQCKECGKAFIRGSQLTQHQRIHTGEKPYGCKECGKAFSHGSQLTLHQRIHTGEKPYECKECRKAFTQSSHLSRHQRVHTGEKPYQCRECGKAFTRGSQLTQHQRIHISEKSFAYKECGIDFSHDSQVYI", "length": 699 }, "evidence": [ { "id": "A0A9J7H8H1", "url": "https://omabrowser.org/oma/group/A0A9J7H8H1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3Z901-1", "protein_name": "Zinc finger protein 420", "gene_name": "LOC134478826", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITHDKMSIFSPGTHLPQHPQGYSTEKPYKCEECGKAFRRASHLSQHHSIHTGEKPYECKQCGKAFSRDSQLSLHQRLHTGEKPYTCKECGKAFTQSSQLILHHRIHTGEKPYKCEACGKAFIRSSQLSRHQKVHTGEKPFECKECGKAFTQNSQLTLHQRLHTGEKLYDCKECRKVFTQLSQLILHRRIHTGEKPYECKECGKAFICGSQLSQHQKTHNGEKPYECKECGKAFIRGSLLMQHQRIHTGEKPYKCDECGKAFIRGSQLTQHQRIHTNEKPYECKECGKTFSHGSQLTQHQRIHTGEKPYQCKECGKAFNRGSLLTRHQRIHTGEKPYKCKECGKDFSRGSELTQHERIHTGEKPYECKECGKSFIRGSQLTQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLHTGEKPYVCSECGKAFARGLLLIQHQRIHTGEKPYECRECGKAFIRGSQLTQHQRTHTGEKPYECRECGKAFGHGSQLTLHQRVHTGEKPYECKECRKAFAQSSHLSRHQRVHTGEKPYQCKECEKAFTRGSQLTQHQRIHISDKSFDCKECRIDLSHHSQIFI", "length": 578 }, "evidence": [ { "id": "A0A9J7H8H1", "url": "https://omabrowser.org/oma/group/A0A9J7H8H1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8TAQ5-1", "protein_name": "Zinc finger protein 420", "gene_name": "ZNF420", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARKLVMFRDVAIDFSQEEWECLDSAQRDLYRDVMLENYSNLVSLDLPSRCASKDLSPEKNTYETELSQWEMSDRLENCDLEESNSRDYLEAKGKMEKQQENQKEYFRQGMIIYDKMSIFNQHTYLSQHSRCHSTEKPYKCKECGKAFRRASHLTQHQSIHTGEKPYECKQCGKAFSRDSQLSLHQRLHTGEKPYACKECGKAFTQSSQLILHHRIHTGEKPYKCEECGKAFIRSSQLTRHQKVHTGEKPYECKECGKAFTQNSQLTLHQRLHTGEKLYECKECRKVFTQLSQLILHKRIHTGEKPYECKECGKAFICGSQLSQHQKIHNGEKPYECKECGRAFIRGSLLMQHQRIHTGEKPYKCEECGKAFIRGSQLTQHQRIHTNEKPYECKECGKMFSHGSQLTQHQRIHTGEKPYQCKECGKAFNRGSLLTRHQRIHTGEKPYECKECGKTFSRGSELTQHERIHTGEKPYECKECGKSFIRGSQLTQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLHTGEKPYVCNECGKAFARGLLLIQHQRIHTGEKPYQCKECGKAFIRGSQLTQHQRIHTGEKPYECKECGKAFSHGSQLTLHQRIHTGEKPYECRECRKAFTQSSHLSRHQRIHTGEKPYQCKECGKAFTRGSQLTQHQRIHISEKSFEYKECGIDFSHGSQVYM", "length": 688 }, "evidence": [ { "id": "A0A9J7H8H1", "url": "https://omabrowser.org/oma/group/A0A9J7H8H1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307588", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307588" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8H2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8H2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100759913", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8H2", "locus": {} } ], "crossref": [ { "id": "A0A9J7H8H2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H8H2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05767", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05767", "database": "CDD", "categories": [ "Protein 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Classification" ] }, { "id": "cge:113832475", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113832475", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H8P4", "url": "https://www.orthodb.org/?gene=A0A9J7H8P4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16675:SF251", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16675:SF251", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307312", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H8P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8P4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRIPVLCALLWLAAILGLAQTGAGSHSLRYFYTIESRPSLREPRFIAVGYVDDTQFVRFDSDAENPRYEPRAQWMEREEPEYWERETRKAKELEQSFRGKLRTLLGYYNQNKGGSHTFQHLSGCHLGSNGRFQRGYEQFAYDGNDYIALNDDLRTWTAADPEAQMAWRKWEQTGEAERHRAYLEGECVEWLHRHLEHGKDQLLRTDPPKTHVTHHPKPDGKVTLRCWALGFYPADITLTWNKDEEELTQDMEIVETRPAGDGTFQKWAAVEVPVGEEQNYTCFVEHEGLPEPLTLRWEPPQSTITIGTIVGAVLGAVILVCIIGGFMMWMRKNTGVEGRVEKETVTLLKVRM", "length": 352, "header": "tr|A0A9J7H8P4-1|A0A9J7H8P4_CRIGR Isoform 1 of H-2 class I histocompatibility antigen, Q10 alpha chain-like OS=Cricetulus griseus OX=10029 GN=LOC113832475 PE=3 SV=1 CANONICAL=A0A9J7H8P4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H8P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8P4/entry#A0A9J7H8P4-1", "sequence": { "sequence": "MRIPVLCALLWLAAILGLAQTGAGSHSLRYFYTIESRPSLREPRFIAVGYVDDTQFVRFDSDAENPRYEPRAQWMEREEPEYWERETRKAKELEQSFRGKLRTLLGYYNQNKGGSHTFQHLSGCHLGSNGRFQRGYEQFAYDGNDYIALNDDLRTWTAADPEAQMAWRKWEQTGEAERHRAYLEGECVEWLHRHLEHGKDQLLRTDPPKTHVTHHPKPDGKVTLRCWALGFYPADITLTWNKDEEELTQDMEIVETRPAGDGTFQKWAAVEVPVGEEQNYTCFVEHEGLPEPLTLRWEPPQSTITIGTIVGAVLGAVILVCIIGGFMMWMRKNTGVEGRVEKETVTLLKVRM", "length": 352, "header": "tr|A0A9J7H8P4-1|A0A9J7H8P4_CRIGR Isoform 1 of H-2 class I histocompatibility antigen, Q10 alpha chain-like OS=Cricetulus griseus OX=10029 GN=LOC113832475 PE=3 SV=1 CANONICAL=A0A9J7H8P4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8P4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8P4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113832475", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113832475", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "antigen processing and presentation of endogenous peptide antigen via MHC class Ib", "id": "GO:0002476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002476", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8P4" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8P4" } ], "pmid": "" }, { "name": "antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent", "id": "GO:0002486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002486", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8P4" } ], "pmid": "" }, { "name": "positive regulation of T cell mediated cytotoxicity", "id": "GO:0001916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001916", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8P4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8P4", "url": 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"XP_035307270", "name": "LOW QUALITY PROTEIN: GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307270" }, "gene_names": [ { "name": "LOC100765573", "type": "recommended", "evidence": [ { "id": "A0A9J7H8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6" } ] }, { "name": "LOC100765573", "type": "synonym", "evidence": [ { "id": "XP_035307270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307270" } ] } ], "protein_names": [ { "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "type": "recommended", "evidence": [ { "id": "A0A9J7H8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.131", "type": "synonym", "evidence": [ { "id": "A0A9J7H8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035307270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307270" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 22% of CDS bases frameshifts :: corrected 1 indel internal stop codons :: corrected 4 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307270", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307270" } ] }, { "annotation": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the fourth and fifth mannose residues to the dolichol-linked oligosaccharide chain, to produce Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide. Man(5)GlcNAc(2)-PP-dolichol is a substrate for ALG3, the following enzyme in the biosynthetic pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6#function" }, { "database": "UniProtKB", "id": "ARBA00045128", "url": "https://www.uniprot.org/uniprotkb/ARBA00045128#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100765573", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6", "locus": {} } ], "crossref": [ { "id": "cd03806", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03806", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765573", "url": "https://www.ncbi.nlm.nih.gov/gene/100765573", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765573", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765573", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H8Q6", "url": "https://www.orthodb.org/?gene=A0A9J7H8Q6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45919", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45919", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45919:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45919:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00534", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00534", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15924", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15924", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307270", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307270", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29523", "url": "https://www.rhea-db.org/rhea/29523", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVVAFFHPYCNAGGGGERVLWCALRALQKKYPEAICVVYTGDINASGQQILEGAVRRFNIKLAHPVQFVFLRKRYLVEDSRYPHFTLLGQSLGSVLLGWEALTQRVPDVYIDSMGYAFTLPLFKYIGSCXIGSYVHYPTISTDMLSVVKNQNTGFNNVAFISRNALLCKAKLIYYYXFVYGRVVPCSDVVMVNSSWTLNHILLLWNVGHCTNIVYPPCDVQTFLDIPLHEKKVTPAYLLVSIGQFRPEKNHNHVFQIKAFAKMLNEKAAESXPSLKLVLIGGCRNKDDELXVSXLRKLSENLGIQENVEFKINISFDELKNYLSEATIGLHTMWNEHFGIGIDECMAAGTIILAHNSGGPKFDIVFPHEGQITGFLAEGEEGYAETMAHILSLSAEKRLQIRRTARASVSMFSDQEFEVSFLSSVEKLGNAKFIISGARAALTSDLLPLKPAGGGGVAGIERSTHLLHSPGSVCQGVGGKRAPSRRQPQPRLGTKVSRKHSVPAPTPLPVPGGGDPRQLLGKSRKGAWGPGSRGRAGAQGAGGGLAGRPRG", "length": 551, "header": "tr|A0A9J7H8Q6-1|A0A9J7H8Q6_CRIGR Isoform 1 of GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Cricetulus griseus OX=10029 GN=LOC100765573 PE=3 SV=1 CANONICAL=A0A9J7H8Q6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H8Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6/entry#A0A9J7H8Q6-1", "sequence": { "sequence": "MVVAFFHPYCNAGGGGERVLWCALRALQKKYPEAICVVYTGDINASGQQILEGAVRRFNIKLAHPVQFVFLRKRYLVEDSRYPHFTLLGQSLGSVLLGWEALTQRVPDVYIDSMGYAFTLPLFKYIGSCXIGSYVHYPTISTDMLSVVKNQNTGFNNVAFISRNALLCKAKLIYYYXFVYGRVVPCSDVVMVNSSWTLNHILLLWNVGHCTNIVYPPCDVQTFLDIPLHEKKVTPAYLLVSIGQFRPEKNHNHVFQIKAFAKMLNEKAAESXPSLKLVLIGGCRNKDDELXVSXLRKLSENLGIQENVEFKINISFDELKNYLSEATIGLHTMWNEHFGIGIDECMAAGTIILAHNSGGPKFDIVFPHEGQITGFLAEGEEGYAETMAHILSLSAEKRLQIRRTARASVSMFSDQEFEVSFLSSVEKLGNAKFIISGARAALTSDLLPLKPAGGGGVAGIERSTHLLHSPGSVCQGVGGKRAPSRRQPQPRLGTKVSRKHSVPAPTPLPVPGGGDPRQLLGKSRKGAWGPGSRGRAGAQGAGGGLAGRPRG", "length": 551, "header": "tr|A0A9J7H8Q6-1|A0A9J7H8Q6_CRIGR Isoform 1 of GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Cricetulus griseus OX=10029 GN=LOC100765573 PE=3 SV=1 CANONICAL=A0A9J7H8Q6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 506, "start_aa": "Thr", "end_pos": 506, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr506", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765573", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765573", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity", "id": "GO:0004377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004377", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29523", "name": "", "equation": "an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3HHJ1-1", "A0A9J7H8Q6-1" ], "evidence": [ { "id": "29523", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29523" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7H8Q6", "gene_name": "LOC100765573", "activity": [ { "ec_number": "2.4.1.131", "activity": "an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+).", "evidence": [ { "id": "A0A9J7H8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6" } ] }, { "ec_number": "2.4.1.131", "activity": "", "evidence": [ { "id": "A0A9J7H8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6" } ] } ] }, { "uniprot_ac": "G3HHJ1", "gene_name": "Alg11", "activity": [ { "ec_number": "2.4.1.131", "activity": "an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+).", "evidence": [ { "id": "G3HHJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HHJ1" } ] }, { "ec_number": "2.4.1.131", "activity": "", "evidence": [ { "id": "G3HHJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HHJ1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6" }, { "id": "PF15924", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15924" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ALG11 mannosyltransferase N-terminal", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 205, "start_aa": "Val", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Q6" }, { "id": "PF00534", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00534" } ], "ann_type": "Domain_Extent_Annotation", 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Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305326" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JTI0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTI0#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A9J7H8S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2#function" }, { "database": "UniProtKB", "id": "A0A9J7GMT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMT8#function" } ] }, { "annotation": "May have a role during differentiation processes.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JTI0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTI0#function" }, { "database": "UniProtKB", "id": "ARBA00053403", "url": "https://www.uniprot.org/uniprotkb/ARBA00053403#function" }, { "database": "UniProtKB", "id": "A0A9J7H8S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2#function" }, { "database": "UniProtKB", "id": "A0A9J7GMT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMT8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC103162235", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2", "locus": {} } ], "crossref": [ { "id": "A0A9J7H8S2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H8S2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "103162235", "url": "https://www.ncbi.nlm.nih.gov/gene/103162235", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103162235", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103162235", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H8S2", "url": "https://www.orthodb.org/?gene=A0A9J7H8S2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF75", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF75", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305326", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GMT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GMT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTI0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGFFLFQRCFSEPHSLPPRNIEEPTGSCSSDTMALAQGSVTFRDVAVDFSKDEWDFLDSAQKSLYRDVMRENYSHFISLGPSISKRDVITLLDKDGKEPEIIVKEGKRRCCPDLESRFKTNTSSADKDIYEVYSLQWELMEKIRSHSPQGSGLRDDWEYESKVERPKEPQKGYLGQWKMTSEKGTYKKHRFLTEYQKVQSGEKFYECKECRKTFIRRSTLSQHLRIHTGEKPYKCKECGQPFRQRAHLIRHYKLHTGEKPYACKECGKAFTVLQELTQHQRLHTGEKPYACKECGKAFRVHQQLARHQRIHTGEKPYECKDCGKTFRQCTHLTRHQRLHTSQKLYDCKECGKAFVCGPDLRVHQKIHFGEKPYACKDCGKSFRICQQLTVHQSIHTGEKPHECKDCGKTFRLRQQLVRHQRIHTREKPYECVDCWKTFSSYPQLISHQSIHAGERPFECEACGKAFRLYSQLTQHQSIHTGEKPYQCKECRKPFRLLSQLSQHQSIHTGEKPYQCKDCGKAFRLYSFLSQHQRIHTGEKPYKCKECKKAFRQHSHLTQHQKIHGGT", "length": 566, "header": "tr|A0A9J7H8S2-1|A0A9J7H8S2_CRIGR Isoform 1 of Zinc finger protein 14 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC103162235 PE=3 SV=1 CANONICAL=A0A9J7H8S2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GMT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2/entry#A0A9J7GMT8-1", "sequence": { "sequence": "MALAQGSVTFRDVAVDFSKDEWDFLDSAQKSLYRDVMRENYSHFISLDLESRFKTNTSSADKDIYEVYSLQWELMEKIRSHSPQGSGLRDDWEYESKVERPKEPQKGYLGQWKMTSEKGTYKKHRFLTEYQKVQSGEKFYECKECRKTFIRRSTLSQHLRIHTGEKPYKCKECGQPFRQRAHLIRHYKLHTGEKPYACKECGKAFTVLQELTQHQRLHTGEKPYACKECGKAFRVHQQLARHQRIHTGEKPYECKDCGKTFRQCTHLTRHQRLHTSQKLYDCKECGKAFVCGPDLRVHQKIHFGEKPYACKDCGKSFRICQQLTVHQSIHTGEKPHECKDCGKTFRLRQQLVRHQRIHTREKPYECVDCWKTFSSYPQLISHQSIHAGERPFECEACGKAFRLYSQLTQHQSIHTGEKPYQCKECRKPFRLLSQLSQHQSIHTGEKPYQCKDCGKAFRLYSFLSQHQRIHTGEKPYKCKECKKAFRQHSHLTQHQKIHGGT", "length": 501, "header": "tr|A0A9J7GMT8-1|A0A9J7GMT8_CRIGR Computationally mapped isoform of Zinc finger protein 14 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC103162235 PE=3 SV=1 CANONICAL=A0A9J7H8S2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H8S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2/entry#A0A9J7H8S2-1", "sequence": { "sequence": "MGFFLFQRCFSEPHSLPPRNIEEPTGSCSSDTMALAQGSVTFRDVAVDFSKDEWDFLDSAQKSLYRDVMRENYSHFISLGPSISKRDVITLLDKDGKEPEIIVKEGKRRCCPDLESRFKTNTSSADKDIYEVYSLQWELMEKIRSHSPQGSGLRDDWEYESKVERPKEPQKGYLGQWKMTSEKGTYKKHRFLTEYQKVQSGEKFYECKECRKTFIRRSTLSQHLRIHTGEKPYKCKECGQPFRQRAHLIRHYKLHTGEKPYACKECGKAFTVLQELTQHQRLHTGEKPYACKECGKAFRVHQQLARHQRIHTGEKPYECKDCGKTFRQCTHLTRHQRLHTSQKLYDCKECGKAFVCGPDLRVHQKIHFGEKPYACKDCGKSFRICQQLTVHQSIHTGEKPHECKDCGKTFRLRQQLVRHQRIHTREKPYECVDCWKTFSSYPQLISHQSIHAGERPFECEACGKAFRLYSQLTQHQSIHTGEKPYQCKECRKPFRLLSQLSQHQSIHTGEKPYQCKDCGKAFRLYSFLSQHQRIHTGEKPYKCKECKKAFRQHSHLTQHQKIHGGT", "length": 566, "header": "tr|A0A9J7H8S2-1|A0A9J7H8S2_CRIGR Isoform 1 of Zinc finger protein 14 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC103162235 PE=3 SV=1 CANONICAL=A0A9J7H8S2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JTI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2/entry#A0A9J7JTI0-1", "sequence": { "sequence": "MGFFLFQRCFSEPHSLPPRNIEEPTGSCSSDTMALAQGSVTFRDVAVDFSKDEWDFLDSAQKSLYRDVMRENYSHFISLDLESRFKTNTSSADKDIYEVYSLQWELMEKIRSHSPQGSGLRDDWEYESKVERPKEPQKGYLGQWKMTSEKGTYKKHRFLTEYQKVQSGEKFYECKECRKTFIRRSTLSQHLRIHTGEKPYKCKECGQPFRQRAHLIRHYKLHTGEKPYACKECGKAFTVLQELTQHQRLHTGEKPYACKECGKAFRVHQQLARHQRIHTGEKPYECKDCGKTFRQCTHLTRHQRLHTSQKLYDCKECGKAFVCGPDLRVHQKIHFGEKPYACKDCGKSFRICQQLTVHQSIHTGEKPHECKDCGKTFRLRQQLVRHQRIHTREKPYECVDCWKTFSSYPQLISHQSIHAGERPFECEACGKAFRLYSQLTQHQSIHTGEKPYQCKECRKPFRLLSQLSQHQSIHTGEKPYQCKDCGKAFRLYSFLSQHQRIHTGEKPYKCKECKKAFRQHSHLTQHQKIHGGT", "length": 533, "header": "tr|A0A9J7JTI0-1|A0A9J7H8S2_CRIGR Computationally mapped isoform of Zinc finger protein 14 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC103162235 PE=3 SV=1 CANONICAL=A0A9J7H8S2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JTI0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTI0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JTI0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTI0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103162235", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103162235", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H8S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 205, "end_pos": 232, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7H8S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S2" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 112, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H8T0-1", "uniprot_ac": "A0A9J7H8T0", "uniprot_id": "A0A9J7H8T0_CRIGR", "mass": { "chemical_mass": 34957.0, "monoisotopic_mass": 34957.0 }, "refseq": { "ac": "XP_035305345", "name": "vomeronasal type-1 receptor 2-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305345" }, "gene_names": [ { "name": "LOC107978890", "type": "recommended", "evidence": [ { "id": "A0A9J7H8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8T0" } ] }, { "name": "LOC107978890", "type": "synonym", "evidence": [ { "id": "XP_035305345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305345" } ] } ], "protein_names": [ { "name": "Vomeronasal type-1 receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7H8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8T0/entry#names_and_taxonomy" } ] }, { "name": "vomeronasal type-1 receptor 2-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305345" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003613842.1) annotated using gene prediction method: Gnomon. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8T9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8T9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760577", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760577", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MIV5-1", "protein_name": "ATP-binding cassette sub-family F member 2", "gene_name": "Abcf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSDLAKKKAAKKKEAAKARQRPRKGHEENGDAVTEPQVAEEKNETNGRETTGDGEVDLLTKELEDFEMKKAAARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLSAVGKREVPIPEHIDIYHLTREMPPSDKTPLQCVMEVDTERAMLEREAERLAHEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSKLVDEEPQLTKRTHNV", "length": 627 }, "evidence": [ { "id": "A0A9J7H8T9", "url": "https://omabrowser.org/oma/group/A0A9J7H8T9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QZ64-1", "protein_name": "ATP-binding cassette sub-family F member 2", "gene_name": "abcf2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPSDLAKKKAAKKKEAAKARGRTRKPEDGVNGDAEKPEIQENGAAEVNGVDSLAKELDEFELKKTEARAVTGVLASHPNSTDVHISSLSLTFHGQELLSDTSLELNSGRRYGLIGLNGTGKSMLLSAISHREVPIPEHIDIYHLTREMAPSEKTALQCVMEVDEERIKLEKEAERLAHEDSECEKLMELYERLEELDADKASMRASRILHGLGFTTSMQQKKLKDFSGGWRMRVALARALFLKPFMLLLDEPTNHLDLDACVWLEEELSQFKRILVLISHSQDFLNGVCTNIIHLHQRKLKYYTGNYDQYVKTREELEENQMKRFNWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLQKMVASGLTERVVNDKTLSFYFPPCGKIPPPVIMVQNVSFRYSENTPYIYKNLEFGIDLDTRVALVGPNGAGKSTLLKLLTGELLPSDGMIRKHSHVKIGRYHQHLTEQLELDLSPLEYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCFAWLAWQNPHMLFLDEPTNHLDIETIDALAEAINDFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWSRDILAYKEHLKSKIDKQMHDL", "length": 613 }, "evidence": [ { "id": "A0A9J7H8T9", "url": "https://omabrowser.org/oma/group/A0A9J7H8T9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P40024-1", "protein_name": "ABC transporter ATP-binding protein ARB1", "gene_name": "ARB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPPVSASKAKRDAKKAEREAKKAAAGKTIRKLGRKKEAAAEESEVDAAAREIKMMKLQQDKDGLSDRVVTGVLSSLETSRDIKLSSVSLLFHGKVLIQDSGLELNYGRRYGLLGENGCGKSTFLKALATREYPIPEHIDIYLLDEPAEPSELSALDYVVTEAQHELKRIEDLVEKTILEDGPESELLEPLYERMDSLDPDTFESRAAIILIGLGFNKKTILKKTKDMSGGWKMRVALAKALFVKPTLLLLDDPTAHLDLEACVWLEEYLKRFDRTLVLVSHSQDFLNGVCTNMIDMRAQKLTAYGGNYDSYHKTRSELETNQMKQYNKQQEEIQHIKKFIASAGTYANLVKQAKSRQKILDKMEADGLVQPVVPDKVFSFRFPQVERLPPPVLAFDDISFHYESNPSENLYEHLNFGVDMDSRIALVGPNGVGKSTLLKIMTGELTPQSGRVSRHTHVKLGVYSQHSQDQLDLTKSALEFVRDKYSNISQDFQFWRGQLGRYGLTGEGQTVQMATLSEGQRSRVVFALLALEQPNVLLLDEPTNGLDIPTIDSLADAINEFNGGVVVVSHDFRLLDKIAQDIFVVENKTATRWDGSILQYKNKLAKNVVL", "length": 610 }, "evidence": [ { "id": "A0A9J7H8T9", "url": "https://omabrowser.org/oma/group/A0A9J7H8T9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q2KJA2-1", "protein_name": "ATP-binding cassette sub-family F member 2", "gene_name": "ABCF2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPSDLAKKKAAKKKEAAKARQRPRKGHEENGDAITEPQVAEERNEEANGRETTEVDLLTKELEDFEMKKAAARAVTGVLASHPNSTDAHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSDKTPLQCVMEVDTERAMLEREAERLAHEDAECEKLLELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINDFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSKLVGEEPQPTRRTHNV", "length": 625 }, "evidence": [ { "id": "A0A9J7H8T9", "url": "https://omabrowser.org/oma/group/A0A9J7H8T9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99LE6-1", "protein_name": "ATP-binding cassette sub-family F member 2", "gene_name": "Abcf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSDLAKKKAAKKKEAAKARQRPRKGHEENGDAVTEPQVAEEKIEEANGRETTGDGEVDLLTKELEDFEMKKAAARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSEKTPLQCVMEVDTERAMLEREAERLAHEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSKLVDEEPQLTKRTHNV", "length": 628 }, "evidence": [ { "id": "A0A9J7H8T9", "url": "https://omabrowser.org/oma/group/A0A9J7H8T9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FJH6-1", "protein_name": "ABC transporter F family member 1", "gene_name": "ABCF1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDASKKKAAQKKAAAAAKRGGKAAAPSKSAATSSNGVDSLSSGVDALQISDRTCTGVLCSHPQSRDIRIESLSVTFHGYDLIVDSMLELNYGRRYGLLGLNGCGKSTLLTAIGRREIPIPDQMDIYHLSHEIEATDMSSLEAVVSCDEERLRLEKEVEILVQQDDGGGERLQSIYERLDAMDAETAEKRAAEILFGLGFDKEMQAKKTKDFSGGWRMRIALARALFIMPTILLLDEPTNHLDLEACVWLEESLKNFDRILVVVSHSQDFLNGVCTNIIHMQSKQLKYYTGNFDQYCQTRSELEENQMKQYRWEQEQISHMKEYIARFGHGSAKLARQAQSKEKTLAKMERGGLTEKVARDSVLVFRFADVGKLPPPVLQFVEVSFGYTPDYLIYKNIDFGVDLDSRVALVGPNGAGKSTLLKLMTGELHPTEGMVRRHNHLKIAQYHQHLAEKLDLELPALLYMMREFPGTEEEKMRAAIGRFGLTGKAQVMPMKNLSDGQRSRVIFAWLAYKQPNMLLLDEPTNHLDIETIDSLAEALNEWDGGLVLVSHDFRLINQVAHEIWVCEKQCITKWNGDIMDFKRHLKAKAGLED", "length": 595 }, "evidence": [ { "id": "A0A9J7H8T9", "url": "https://omabrowser.org/oma/group/A0A9J7H8T9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9UG63-1", "protein_name": "ATP-binding cassette sub-family F member 2", "gene_name": "ABCF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSDLAKKKAAKKKEAAKARQRPRKGHEENGDVVTEPQVAEKNEANGRETTEVDLLTKELEDFEMKKAAARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLAHEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSKLVDEEPQLTKRTHNV", "length": 623 }, "evidence": [ { "id": "A0A9J7H8T9", "url": "https://omabrowser.org/oma/group/A0A9J7H8T9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VXR5-1", "protein_name": "ATP-binding cassette sub-family F member 2", "gene_name": "Dmel\\CG9281", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSAAKKREAQKKKDARNKKIQQIPSTKKANGVPERELTEEEKLCAKLEEEARISAEARSCTGSLAVHPRSRDVKIANFSITFFGSELLQDTMLELNCGRRYGLIGLNGCGKSSLLAVLGGREVPVPPHIDIFHLTREIPASSKSALQCVMEVDEERIKLEKLAEELAMSEEDDAQEQLIDIYERLDDMSADLAEVKAARILHGLGFDKAMQQKQAKDFSGGWRMRIALARALFVKPHLLLLDEPTNHLDLDACVWLEEELKTYKRILVLISHSQDFLNGVCTNIIHLTGKRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQISHMKNYIARFGHGSAKLARQAQSKEKTLAKMVAQGLTEKVSDDKVLNFYFPSCGKVPPPVIMVQNVNFRYNDETPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPTSGMIRKNSHLRIARYHQHLHELLDLDASPLEYMMRAFPDVKEKEEMRKIIGRYGLTGRQQVCPIRQLSDGQRCRVVFAWLAWQVPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRLINQVAEEIWVCEKETVTKWKGGILDYKDHLKNKITSENEKKAKAGK", "length": 611 }, "evidence": [ { "id": "A0A9J7H8T9", "url": "https://omabrowser.org/oma/group/A0A9J7H8T9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8T9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8T9" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8T9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8T9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8T9" }, { "id": "PS50893", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transporter", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 327, "start_aa": "Val", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 402, "end_pos": 404 }, { "start_pos": 518, "end_pos": 520 }, { "start_pos": 84, "end_pos": 86 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H8U0-1", "uniprot_ac": "A0A9J7H8U0", "uniprot_id": "A0A9J7H8U0_CRIGR", "mass": { "chemical_mass": 63383.0, "monoisotopic_mass": 63383.0 }, "refseq": { "ac": "XP_035305361", "name": "coiled-coil domain-containing protein 61 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305361" }, "gene_names": [ { "name": "LOC100758950", "type": "recommended", "evidence": [ { "id": "A0A9J7H8U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U0" } ] }, { "name": "LOC100758950", "type": "synonym", "evidence": [ { "id": "XP_035305361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305361" } ] } ], "protein_names": [ { "name": "Centrosomal protein CCDC61", "type": "recommended", "evidence": [ { "id": "A0A9J7H8U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U0/entry#names_and_taxonomy" } ] }, { "name": "Coiled-coil domain-containing protein 61", "type": "synonym", "evidence": [ { "id": "A0A9J7H8U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U0/entry#names_and_taxonomy" } ] }, { "name": "VFL3 homolog", "type": "synonym", "evidence": [ { "id": "A0A9J7H8U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U0/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 61 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305361" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305361", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305361" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8U0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100758950", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U0", "locus": {} } ], "crossref": [ { "id": "A0A9J7H8U0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H8U0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22284", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22284", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758950", "url": "https://www.ncbi.nlm.nih.gov/gene/100758950", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR049733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758950", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758950", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H8U0", "url": "https://www.orthodb.org/?gene=A0A9J7H8U0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22691", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22691", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22691:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22691:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27933", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27933", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27935", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27935", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305361", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305361", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GLX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GLX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8U0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KD26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KD26-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD26-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGKVKPIRSEKAGSGAEPKVRRLNRSWRGASVEPVCGNCAGAGTLAMNQPTVLQVDYFFRGVEHAVRVVVSGQVLELEVEDRMTADQWRGEFDANFIEDLTHKTGNFKQFSIFCNMLESALTQSSESVTLDLLTYTDLESLRSRKLGGRPGSLAPRSAQLNSKRYLILIYSVEFDRIHYPLPLPYQGKPDPVVLQGIIRSLKEELGRLRGLDGGQDTRDTREAEIWHLREQVTRLASEKRELEVQLGRSREEALAGRAARQEAEALRGLVRGLETELRQERGLGGRAAGRRSQDCRRLAKEVRLEEVKASERNLRARLKTLNNELALYRRGRRNLPASAPAREDRASTSRERSTSRGRAATRSSSRRAAAGPGSRPAARPSPSPTGARAPRFDPTAFVKAKEKKQREIRMKQQQQQQQLQQRNRTGSGGSGDGPSVSWTQQTRPATAMTARGDANRSRNRSSSVDSFRSRCSSVSSCSDLDFSESVSRSRRCRVRGKPPSPTPWSGRKMKSTTRERSNHQRHLANSGGWVPVKEYSPEYQGADMAEIDARLKALQEYMNRLDTRS", "length": 567, "header": "tr|A0A9J7H8U0-1|A0A9J7H8U0_CRIGR Isoform 1 of Centrosomal protein CCDC61 OS=Cricetulus griseus OX=10029 GN=LOC100758950 PE=3 SV=1 CANONICAL=A0A9J7H8U0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GLX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U0/entry#A0A9J7GLX7-1", "sequence": { "sequence": "MAAGKVKPIRSEKAGSGAEPKVRRLNRSWRGASVEPVCGNCAGAGTLAMNQPTVLQVDYFFRGVEHAVRVVVSGQVLELEVEDRMTADQWRGEFDANFIEDLTHKTGNFKQFSIFCNMLESALTQSSESVTLDLLTYTDLESLRSRKLGGRPGSLAPRSAQLNSKRYLILIYSVEFDRIHYPLPLPYQGKPDPVVLQGIIRSLKEELGRLRGLDGGQDTRDTREAEIWHLREQVTRLASEKRELEVQLGRSREEALAGRAARQEAEALRGLVRGLETELRQERGLGGRAAGRRSQDCRRLAKELEEVKASERNLRARLKTLNNELALYRRGRRNLPASAPAREDRASTSRERSTSRGRAATRSSSRRAAAGPGSRPAARPSPSPTGARAPRFDPTAFVKAKEKKQREIRMKQQQQQQQLQQRNRTGSGGSGDGPSVSWTQQTRPATAMTARGDANRSRNRSSSVDSFRSRCSSVSSCSDLDFSESVSRSRRCRVRGKPPSPTPWSGRKMKSTTRERSNHQRHLANSGGWVPVKEYSPEYQGADMAEIDARLKALQEYMNRLDTRS", "length": 565, "header": "tr|A0A9J7GLX7-1|A0A9J7GLX7_CRIGR Computationally mapped isoform of Centrosomal protein CCDC61 OS=Cricetulus griseus OX=10029 GN=LOC100758950 PE=3 SV=1 CANONICAL=A0A9J7H8U0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H8U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U0/entry#A0A9J7H8U0-1", "sequence": { "sequence": "MAAGKVKPIRSEKAGSGAEPKVRRLNRSWRGASVEPVCGNCAGAGTLAMNQPTVLQVDYFFRGVEHAVRVVVSGQVLELEVEDRMTADQWRGEFDANFIEDLTHKTGNFKQFSIFCNMLESALTQSSESVTLDLLTYTDLESLRSRKLGGRPGSLAPRSAQLNSKRYLILIYSVEFDRIHYPLPLPYQGKPDPVVLQGIIRSLKEELGRLRGLDGGQDTRDTREAEIWHLREQVTRLASEKRELEVQLGRSREEALAGRAARQEAEALRGLVRGLETELRQERGLGGRAAGRRSQDCRRLAKEVRLEEVKASERNLRARLKTLNNELALYRRGRRNLPASAPAREDRASTSRERSTSRGRAATRSSSRRAAAGPGSRPAARPSPSPTGARAPRFDPTAFVKAKEKKQREIRMKQQQQQQQLQQRNRTGSGGSGDGPSVSWTQQTRPATAMTARGDANRSRNRSSSVDSFRSRCSSVSSCSDLDFSESVSRSRRCRVRGKPPSPTPWSGRKMKSTTRERSNHQRHLANSGGWVPVKEYSPEYQGADMAEIDARLKALQEYMNRLDTRS", "length": 567, "header": "tr|A0A9J7H8U0-1|A0A9J7H8U0_CRIGR Isoform 1 of Centrosomal protein CCDC61 OS=Cricetulus griseus OX=10029 GN=LOC100758950 PE=3 SV=1 CANONICAL=A0A9J7H8U0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KD26-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U0/entry#A0A9J7KD26-1", "sequence": { "sequence": "MNQPTVLQVDYFFRGVEHAVRVVVSGQVLELEVEDRMTADQWRGEFDANFIEDLTHKTGNFKQFSIFCNMLESALTQSSESVTLDLLTYTDLESLRSRKLGGRPGSLAPRSAQLNSKRYLILIYSVEFDRIHYPLPLPYQGKPDPVVLQGIIRSLKEELGRLRGLDGGQDTRDTREAEIWHLREQVTRLASEKRELEVQLGRSREEALAGRAARQEAEALRGLVRGLETELRQERGLGGRAAGRRSQDCRRLAKEVRLEEVKASERNLRARLKTLNNELALYRRGRRNLPASAPAREDRASTSRERSTSRGRAATRSSSRRAAAGPGSRPAARPSPSPTGARAPRFDPTAFVKAKEKKQREIRMKQQQQQQQLQQRNRTGSGGSGDGPSVSWTQQTRPATAMTARGDANRSRNRSSSVDSFRSRCSSVSSCSDLDFSESVSRSRRCRVRGKPPSPTPWSGRKMKSTTRERSNHQRHLANSGGWVPVKEYSPEYQGADMAEIDARLKALQEYMNRLDTRS", "length": 519, "header": "tr|A0A9J7KD26-1|A0A9J7H8U0_CRIGR Computationally mapped isoform of Centrosomal protein CCDC61 OS=Cricetulus griseus OX=10029 GN=LOC100758950 PE=3 SV=1 CANONICAL=A0A9J7H8U0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 504, "start_aa": "Thr", "end_pos": 504, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr504", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KD26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD26" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KD26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD26" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758950", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758950", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8U0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U0" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8U0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H8U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U0" }, { "id": "PF27933", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27933" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Coiled-coil", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 192, "start_aa": "Gln", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 504 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 26, "end_pos": 28 }, { "start_pos": 425, "end_pos": 427 }, { "start_pos": 457, "end_pos": 459 }, { "start_pos": 461, "end_pos": 463 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H8U5-1", "uniprot_ac": "A0A9J7H8U5", "uniprot_id": "A0A9J7H8U5_CRIGR", "mass": { "chemical_mass": 24746.0, "monoisotopic_mass": 24746.0 }, "refseq": { "ac": "XP_035307221", "name": "ras-related protein Rab-25 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307221" }, "gene_names": [ { "name": "Rab25", "type": "recommended", "evidence": [ { "id": "A0A9J7H8U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U5" } ] }, { "name": "Rab25", "type": "synonym", "evidence": [ { "id": "XP_035307221", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307221" } ] } ], "protein_names": [ { "name": "Ras-related protein Rab-25", "type": "recommended", "evidence": [ { "id": "A0A9J7H8U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U5/entry#names_and_taxonomy" } ] }, { "name": "ras-related protein Rab-25 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035307221", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307221" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 4% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307221" } ] }, { "annotation": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB25 regulates epithelial cell differentiation, proliferation and survival, thereby playing key roles in tumorigenesis. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions. May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8U5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U5#function" }, { "database": "UniProtKB", "id": "ARBA00055320", "url": "https://www.uniprot.org/uniprotkb/ARBA00055320#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8U5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rab25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U5", "locus": {} } ], "crossref": [ { "id": "A0A9J7H8U5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H8U5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01868", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01868", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757986", "url": "https://www.ncbi.nlm.nih.gov/gene/100757986", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757986", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757986", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H8U5", "url": "https://www.orthodb.org/?gene=A0A9J7H8U5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47979", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47979", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307221", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H8U5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKCGTLAQVGSERLCPGSALRSPLSTSSVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAVKAQIWDTAGLERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLSQAREVPTEEACMFAENNGLLFLETSALDSTNVELAFQTVLKEIFAKVSKQRQNSTRANAITLGNAEAGQDSGPGEKRACCINL", "length": 228, "header": "tr|A0A9J7H8U5-1|A0A9J7H8U5_CRIGR Isoform 1 of Ras-related protein Rab-25 OS=Cricetulus griseus OX=10029 GN=Rab25 PE=3 SV=1 CANONICAL=A0A9J7H8U5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H8U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U5/entry#A0A9J7H8U5-1", "sequence": { "sequence": "MEKCGTLAQVGSERLCPGSALRSPLSTSSVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAVKAQIWDTAGLERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLSQAREVPTEEACMFAENNGLLFLETSALDSTNVELAFQTVLKEIFAKVSKQRQNSTRANAITLGNAEAGQDSGPGEKRACCINL", "length": 228, "header": "tr|A0A9J7H8U5-1|A0A9J7H8U5_CRIGR Isoform 1 of Ras-related protein Rab-25 OS=Cricetulus griseus OX=10029 GN=Rab25 PE=3 SV=1 CANONICAL=A0A9J7H8U5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"XP_035307350", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307350" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 6% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307350", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307350" } ] }, { "annotation": "Lysosomal thiol reductase that can reduce protein disulfide bonds. Facilitates the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8U7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U7#function" }, { "database": "UniProtKB", "id": "RU369109", "url": "https://www.uniprot.org/uniprotkb/RU369109#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8U7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ifi30", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U7", "locus": {} } ], "crossref": [ { "id": "A0A9J7H8U7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H8U7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100759310", "url": "https://www.ncbi.nlm.nih.gov/gene/100759310", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759310", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759310", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H8U7", "url": "https://www.orthodb.org/?gene=A0A9J7H8U7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13234:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13234:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307350", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307350", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H8U7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWCDRTCWPQEEGTLEGGPCGLEPGRGVVSGGGASACLKSPTSKAQPAVVPTFSSAAMPRSLFLPLLPLLLLLLPEAPRAARVSPLQASSEAAATCKAHDLCLLGPRPLPPAPPVNVSLYYESLCGACRYFLVRDLFPTWLMVMEIINVTLVPYGNAQERNVSGTWEFTCQHGELECRLNKVEACLLDKLEKEAALLTIVCVEEMQDMEKKLGPCLQVYAPEVSPDSIMECATGERGTQLMHANAQLTEALQPPHEYVPWVLVNEKPLKDPSQLLSTVCQLYQGVEKPDICSSMADPPRKVCYK", "length": 304, "header": "tr|A0A9J7H8U7-1|A0A9J7H8U7_CRIGR Isoform 1 of Gamma-interferon-inducible lysosomal thiol reductase OS=Cricetulus griseus OX=10029 GN=Ifi30 PE=3 SV=1 CANONICAL=A0A9J7H8U7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H8U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U7/entry#A0A9J7H8U7-1", "sequence": { "sequence": "MWCDRTCWPQEEGTLEGGPCGLEPGRGVVSGGGASACLKSPTSKAQPAVVPTFSSAAMPRSLFLPLLPLLLLLLPEAPRAARVSPLQASSEAAATCKAHDLCLLGPRPLPPAPPVNVSLYYESLCGACRYFLVRDLFPTWLMVMEIINVTLVPYGNAQERNVSGTWEFTCQHGELECRLNKVEACLLDKLEKEAALLTIVCVEEMQDMEKKLGPCLQVYAPEVSPDSIMECATGERGTQLMHANAQLTEALQPPHEYVPWVLVNEKPLKDPSQLLSTVCQLYQGVEKPDICSSMADPPRKVCYK", "length": 304, "header": "tr|A0A9J7H8U7-1|A0A9J7H8U7_CRIGR Isoform 1 of Gamma-interferon-inducible lysosomal thiol reductase OS=Cricetulus griseus OX=10029 GN=Ifi30 PE=3 SV=1 CANONICAL=A0A9J7H8U7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"A0A9J7H8W5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8W5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8W5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8W5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8W5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8W5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1058, "end_pos": 1060, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 671, "end_pos": 673, "annotation": "n_glycosylation_sequon" }, { 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"https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { 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"https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] } ] }, { "uniprot_ac": "A0A8C2N185", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] } ] }, { "uniprot_ac": "A0A8C2N210", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] } ] }, { "uniprot_ac": "A0A8C2N3I1", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] } ] }, { "uniprot_ac": "A0A8C2N3U2", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] } ] }, { "uniprot_ac": "A0A8C2N457", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] } ] }, { "uniprot_ac": "A0A8C2N4W2", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] } ] }, { "uniprot_ac": "A0A8C2N6L4", "gene_name": "Prkg1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N6L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L4" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8C2N6L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L4" } ] } ] }, { "uniprot_ac": "A0A8C2N756", "gene_name": "Map2k5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N756" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2N756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N756" } ] } ] }, { "uniprot_ac": "A0A8C2N9X1", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N9X1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2N9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N9X1" } ] } ] }, { "uniprot_ac": "A0A8C2QDX9", "gene_name": "Csnk1g1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] } ] }, { "uniprot_ac": "A0A8C2QEB8", "gene_name": "Bub1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEB8" } ] } ] }, { "uniprot_ac": "A0A8C2QGY5", "gene_name": "Ttbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QGY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGY5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QGY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGY5" } ] } ] }, { "uniprot_ac": "A0A8C2QH69", "gene_name": "Sgk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QH69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QH69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH69" } ] } ] }, { "uniprot_ac": "A0A8C2QHF9", "gene_name": "Lrrk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] } ] }, { "uniprot_ac": "A0A8C2QHS8", "gene_name": "Ripk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] } ] }, { "uniprot_ac": "A0A8C2QI80", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] } ] }, { "uniprot_ac": "A0A8C2QIA1", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] } ] }, { "uniprot_ac": "A0A8C2QJ34", "gene_name": "Oxsr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] } ] }, { "uniprot_ac": "A0A8C2QJA4", "gene_name": "Pak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJA4" } ] } ] }, { "uniprot_ac": "A0A8C2QKP7", "gene_name": "Nlk", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QKP7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QKP7" } ] } ] }, { "uniprot_ac": "A0A8C2QL63", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] } ] }, { "uniprot_ac": "A0A8C2QLT0", "gene_name": "Nek9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] } ] }, { "uniprot_ac": "A0A8C2QMB3", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] } ] }, { "uniprot_ac": "A0A8C2QND0", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] } ] }, { "uniprot_ac": "A0A8C2QNX2", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] } ] }, { "uniprot_ac": "A0A8C2QPB0", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] } ] }, { "uniprot_ac": "A0A9J7EUQ5", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] } ] }, { "uniprot_ac": "A0A9J7EVK4", "gene_name": "Bmp2k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] } ] }, { "uniprot_ac": "A0A9J7EVN3", "gene_name": "LOC100754361", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] } ] }, { "uniprot_ac": "A0A9J7EXX8", "gene_name": "LOC113832238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] } ] }, { "uniprot_ac": "A0A9J7F0J6", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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} ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ 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"https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] } ] }, { "uniprot_ac": "A0A9J7GP29", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] } ] }, { "uniprot_ac": "A0A9J7H3M5", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] } ] }, { "uniprot_ac": "A0A9J7H3N1", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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{ "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JQZ1", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] } ] }, { "uniprot_ac": "A0A9J7JRI3", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", 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"count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H8Z9-1", "uniprot_ac": "A0A9J7H8Z9", "uniprot_id": "A0A9J7H8Z9_CRIGR", "mass": { "chemical_mass": 80570.0, "monoisotopic_mass": 80570.0 }, "refseq": { "ac": "XP_035305494", "name": "LOW QUALITY PROTEIN: tRNA wybutosine-synthesizing protein 2 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305494" }, "gene_names": [ { "name": "LOC113837486", "type": "recommended", "evidence": [ { "id": "A0A9J7H8Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z9" } ] }, { "name": "LOC113837486", "type": "synonym", "evidence": [ { "id": "XP_035305494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305494" } ] } ], "protein_names": [ { "name": "tRNA wybutosine-synthesizing protein 2 homolog", "type": "recommended", "evidence": [ { "id": "A0A9J7H8Z9", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305494", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305494" } ] }, { "annotation": "S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF25133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305494", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305494", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36355", "url": "https://www.rhea-db.org/rhea/36355", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H8Z9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTGLSYWRGKHAVVRRHHCLMAQRLHGITADERFRGQERGSRITHTALSTTRRRRRLVLTLLADPNKHGGGGFTAPRGASSLIAGAPLGPARPLTSLPARRAGDLRASERAIDARGGRMEEIGAEPPAVVAVVTEPRFAQTYRDFLERRRLLDGRQRVRRLRDDAVALPLLAGAGAAPEQLLRELRERVAPGSSCSLQRLPSPSPSPSAETRGCSPAARLARELRLLLRERGLPWSPELQADLPRTWRRHGDLLLLGDRCFRAEPWRSLGSELWVAVASALGARRVARRGPVQPDGARTPSVTLLLGEHGWVEHRDNGIRYAFDVTRCMFSCGNVAEKLRVASLACAGEVVVDLYAGIGYFTLPFLVHAGAAFVHACEWNPHAALALRRNLQLNGVAHRCRVHLGDNRELPLRDAADRVNLGLLPSSEAGWPVACRVLRKDAGGILHIHQNVESFSGKSPQKGVPEDEPGAPPGDPLPAAARPEWRSWAASAGARIAALLEQVHGKQWSTRVLRVHPVKSYAPHVDHLVLDLECRPLLXSWLEGVTLGDTVAPREGLTASAEFSLTLRFPVLFSNADVEASGKDETVATAPLIRDTVTTAGPSQLHTGREAPPQGYPKDEEGSCAPRVRLLSQEETVLPAVLSSAHADRHTDGRTDREGGRRVHGGERCFAPPGSILAGTAVGCRRLAGSSDTPRPDSGGDGRAGQHPRAPGMLTGSPALRRSAASIPPLPGASPTGPAHAPPPARP", "length": 748, "header": "tr|A0A9J7H8Z9-1|A0A9J7H8Z9_CRIGR Isoform 1 of tRNA wybutosine-synthesizing protein 2 homolog OS=Cricetulus griseus OX=10029 GN=LOC113837486 PE=4 SV=1 CANONICAL=A0A9J7H8Z9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H8Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z9/entry#A0A9J7H8Z9-1", "sequence": { "sequence": "MDTGLSYWRGKHAVVRRHHCLMAQRLHGITADERFRGQERGSRITHTALSTTRRRRRLVLTLLADPNKHGGGGFTAPRGASSLIAGAPLGPARPLTSLPARRAGDLRASERAIDARGGRMEEIGAEPPAVVAVVTEPRFAQTYRDFLERRRLLDGRQRVRRLRDDAVALPLLAGAGAAPEQLLRELRERVAPGSSCSLQRLPSPSPSPSAETRGCSPAARLARELRLLLRERGLPWSPELQADLPRTWRRHGDLLLLGDRCFRAEPWRSLGSELWVAVASALGARRVARRGPVQPDGARTPSVTLLLGEHGWVEHRDNGIRYAFDVTRCMFSCGNVAEKLRVASLACAGEVVVDLYAGIGYFTLPFLVHAGAAFVHACEWNPHAALALRRNLQLNGVAHRCRVHLGDNRELPLRDAADRVNLGLLPSSEAGWPVACRVLRKDAGGILHIHQNVESFSGKSPQKGVPEDEPGAPPGDPLPAAARPEWRSWAASAGARIAALLEQVHGKQWSTRVLRVHPVKSYAPHVDHLVLDLECRPLLXSWLEGVTLGDTVAPREGLTASAEFSLTLRFPVLFSNADVEASGKDETVATAPLIRDTVTTAGPSQLHTGREAPPQGYPKDEEGSCAPRVRLLSQEETVLPAVLSSAHADRHTDGRTDREGGRRVHGGERCFAPPGSILAGTAVGCRRLAGSSDTPRPDSGGDGRAGQHPRAPGMLTGSPALRRSAASIPPLPGASPTGPAHAPPPARP", "length": 748, "header": "tr|A0A9J7H8Z9-1|A0A9J7H8Z9_CRIGR Isoform 1 of tRNA wybutosine-synthesizing protein 2 homolog OS=Cricetulus griseus OX=10029 GN=LOC113837486 PE=4 SV=1 CANONICAL=A0A9J7H8Z9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Z9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Z9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113837486", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837486", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "tRNA methyltransferase activity", "id": "GO:0008175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008175", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H8Z9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z9" } ], "pmid": "" }, { "name": "tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity", "id": "GO:0102522", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z9" } ] }, { "ec_number": "2.5.1.114", "activity": "", "evidence": [ { "id": "A0A9J7H8Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z9" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H8Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8Z9" }, { "id": "PS51684", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51684" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM-dependent methyltransferase TRM5/TYW2-type", "eco_id": "ECO_0000259", "start_pos": 248, "end_pos": 537, "start_aa": "Trp", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.5.1.114", "ec_name": "4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 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genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307454" } ] }, { "annotation": "Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins. Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H901", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H901#function" }, { "database": "UniProtKB", "id": "ARBA00053549", "url": "https://www.uniprot.org/uniprotkb/ARBA00053549#function" }, { "database": "UniProtKB", "id": "A0A061IIP4", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H901", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H901" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Bola1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H901", "locus": {} } ], "crossref": [ { "id": "A0A9J7H901", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H901", "database": "AlphaFoldDB", "categories": [] }, { "id": "100758926", "url": "https://www.ncbi.nlm.nih.gov/gene/100758926", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036065", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036065", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758926", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758926", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H901", "url": "https://www.orthodb.org/?gene=A0A9J7H901", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46229", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46229", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46229:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46229:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01722", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01722", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307454", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IIP4", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IIP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H901", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H901", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H901-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H901-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEMQSLEFAQLVFDLALIQCFLTTFPSLHFGMRMLRAQLARCTVPMATRACASRDSAGSAAGGPVEAAIRAKLEQALSPEVLELRNESGGHAVPAGSETHFRVAVVSSRFEGMSPLQRHRLVHAALSEELAGPVHALAIQAKTPAQWRENPQLDTSPPCLGGSKKTRGTS", "length": 170, "header": "tr|A0A9J7H901-1|A0A9J7H901_CRIGR Isoform 1 of BolA-like protein 1 OS=Cricetulus griseus OX=10029 GN=Bola1 PE=3 SV=1 CANONICAL=A0A9J7H901-1" }, "isoforms": [ { "isoform_ac": "A0A061IIP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H901/entry#A0A061IIP4-1", "sequence": { "sequence": "MLRAQLARCTVPMATRACASRDSAGSAAGGPVEAAIRAKLEQALSPEVLELRNESGGHAVPAGSETHFRVAVVSSRFEGMSPLQRHRLVHAALSEELAGPVHALAIQAKTPAQWRENPQLDTSPPCLGGSKKTRGTS", "length": 137, "header": "tr|A0A061IIP4-1|A0A061IIP4_CRIGR Computationally mapped isoform of BolA-like protein 1 OS=Cricetulus griseus OX=10029 GN=Bola1 PE=3 SV=1 CANONICAL=A0A9J7H901-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H901-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H901/entry#A0A9J7H901-1", "sequence": { "sequence": "MEMQSLEFAQLVFDLALIQCFLTTFPSLHFGMRMLRAQLARCTVPMATRACASRDSAGSAAGGPVEAAIRAKLEQALSPEVLELRNESGGHAVPAGSETHFRVAVVSSRFEGMSPLQRHRLVHAALSEELAGPVHALAIQAKTPAQWRENPQLDTSPPCLGGSKKTRGTS", "length": 170, "header": "tr|A0A9J7H901-1|A0A9J7H901_CRIGR Isoform 1 of BolA-like protein 1 OS=Cricetulus griseus OX=10029 GN=Bola1 PE=3 SV=1 CANONICAL=A0A9J7H901-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H901", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H901" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H901", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H901" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758926", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758926", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H901", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H901" } ], "pmid": "" }, { "name": "iron-sulfur cluster assembly complex", "id": "GO:1990229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990229", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H901", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H901" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 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"function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307321", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307321" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H903", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H903" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100764815", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H903", "locus": {} } ], "crossref": [ { "id": "A0A9J7H903", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H903", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05713", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05713", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764815", "url": "https://www.ncbi.nlm.nih.gov/gene/100764815", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053896", "url": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22705", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22705", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307321", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307321", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H903", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H903", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H903-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H903-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGSPTFPPDGCLLSLLLLVSTIVSGEVSSFSVRGQTEPITVLLGAEATLPCQLSPAQSASPMHIRWYRARLTPAVLVFHDGQEQGDVQMPEYRGRTRLVRDAIATGDVTLQIQQVQASDDGLYHCQVTHGFTSQEAVIELRVKGLGSAPLVRMTGPENNGIQVSCSSSGWFPKPRVQWRNNAGDTLLSSSESQTQDGAGLFHVETSLLVTDRAVGNVTCSIQNPLHDQEEVKAIFLPEPFFPRTSPWKVALACLLPILLVLFGGTSLAGWKEHQAKRREVEKKSAEQQEMSQKKEEMKIALKKRDDLQAELDQRKALYREDWKKALLYPDWRKELFQLAPVRIKHEVTHQDKPGPETEESSREETAHPSLSSPQEDHNIITLYQEGFMLGRYYWEVDVGDTEEWTLGVYELSTQDVPSRESLRKFRVLEKKGDEYRALAFCSQAVSLEEPLLLETRPLKIAIFLDQEDNDLSFYNMTDETHIFSFAQARFLGSLYPYFTRHPVGLSPSHSPK", "length": 513, "header": "tr|A0A9J7H903-1|A0A9J7H903_CRIGR Isoform 1 of Butyrophilin-like protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100764815 PE=3 SV=1 CANONICAL=A0A9J7H903-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H903-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H903/entry#A0A9J7H903-1", "sequence": { "sequence": "MKGSPTFPPDGCLLSLLLLVSTIVSGEVSSFSVRGQTEPITVLLGAEATLPCQLSPAQSASPMHIRWYRARLTPAVLVFHDGQEQGDVQMPEYRGRTRLVRDAIATGDVTLQIQQVQASDDGLYHCQVTHGFTSQEAVIELRVKGLGSAPLVRMTGPENNGIQVSCSSSGWFPKPRVQWRNNAGDTLLSSSESQTQDGAGLFHVETSLLVTDRAVGNVTCSIQNPLHDQEEVKAIFLPEPFFPRTSPWKVALACLLPILLVLFGGTSLAGWKEHQAKRREVEKKSAEQQEMSQKKEEMKIALKKRDDLQAELDQRKALYREDWKKALLYPDWRKELFQLAPVRIKHEVTHQDKPGPETEESSREETAHPSLSSPQEDHNIITLYQEGFMLGRYYWEVDVGDTEEWTLGVYELSTQDVPSRESLRKFRVLEKKGDEYRALAFCSQAVSLEEPLLLETRPLKIAIFLDQEDNDLSFYNMTDETHIFSFAQARFLGSLYPYFTRHPVGLSPSHSPK", "length": 513, "header": "tr|A0A9J7H903-1|A0A9J7H903_CRIGR Isoform 1 of Butyrophilin-like protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100764815 PE=3 SV=1 CANONICAL=A0A9J7H903-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H903", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H903" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H903", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H903" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764815", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764815", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H903", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H903" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H903", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H903" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H903", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H903" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H903", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H903" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H909-1", "uniprot_ac": "A0A9J7H909", "uniprot_id": "A0A9J7H909_CRIGR", "mass": { "chemical_mass": 62918.0, "monoisotopic_mass": 62918.0 }, "refseq": { "ac": "XP_035307555", "name": "EGF-like and EMI domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307555" }, "gene_names": [ { "name": "LOC100765263", "type": "recommended", "evidence": [ { "id": "A0A9J7H909", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H909" } ] }, { "name": "LOC100765263", "type": "synonym", "evidence": [ { "id": "XP_035307555", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307555" } ] } ], "protein_names": [ { "name": "EGF-like and EMI domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035307555", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307555" }, { "id": "A0A9J7H909", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H909/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307555" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H909", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H909" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100765263", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H909", "locus": {} } ], "crossref": [ { "id": "A0A9J7H909", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H909", "database": "AlphaFoldDB", "categories": [] }, { "id": "100765263", "url": "https://www.ncbi.nlm.nih.gov/gene/100765263", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765263", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765263", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H909", "url": "https://www.orthodb.org/?gene=A0A9J7H909", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24035", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24035", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24035:SF138", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24035:SF138", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24050", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24050", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24050:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24050:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307555", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H909", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H909", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H909-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H909-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H964", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H964-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H964-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSPLWFWCFCVWAADRWPPGSALQLQPGMPNVCKEEQLTVVGLSRPCTQAFIETVKFWKQGCTGLRWCVAYERRTRYYTIYRQVYVTEHQTVFRCCPGWSRWNDEPGCLSSVSSLGTHFSGRLCSDGADLQCLCSQGFHGPHCQYDINECAVDNGGCHDQCCNTIGSYYCKCQAGQKLEEDGKGCEDIDECAVVNGGCQQRCINTLGTFHCECDTGYRRHADERTCIKTDPCAGGNGCAHLCQSENGVARCTCHAGYQLSEDKKACEDINECAEELVPCAHRCVNSEGSFTCACHPGFELGADGKHCYRIELEIVNICEENNGGCSHHCEPAIGGPHCSCNHGHQLDADEKTCIALDDEQFEEEEEVLDILRFPGLLVQSSPQPLPYYAPSLTASYEDENNDEEDQEAEGEFQGLTALQRVVCLDGTFGPDCSLSCEDCMNGGRCQEGESGCVCPEGWNGILCNESNTQRTGMDQQAPLGCLKGFFGKDCKRKCHCAKDGHCHRVYGACICDLGRYGRFCHLSCPRGTYGAGCSLECQCVEENTLDCSAKNGSCTCKSGYQGNRCQEGTIQ", "length": 572, "header": "tr|A0A9J7H909-1|A0A9J7H909_CRIGR Isoform 1 of EGF-like and EMI domain-containing protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100765263 PE=3 SV=1 CANONICAL=A0A9J7H909-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H909-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H909/entry#A0A9J7H909-1", "sequence": { "sequence": "MTSPLWFWCFCVWAADRWPPGSALQLQPGMPNVCKEEQLTVVGLSRPCTQAFIETVKFWKQGCTGLRWCVAYERRTRYYTIYRQVYVTEHQTVFRCCPGWSRWNDEPGCLSSVSSLGTHFSGRLCSDGADLQCLCSQGFHGPHCQYDINECAVDNGGCHDQCCNTIGSYYCKCQAGQKLEEDGKGCEDIDECAVVNGGCQQRCINTLGTFHCECDTGYRRHADERTCIKTDPCAGGNGCAHLCQSENGVARCTCHAGYQLSEDKKACEDINECAEELVPCAHRCVNSEGSFTCACHPGFELGADGKHCYRIELEIVNICEENNGGCSHHCEPAIGGPHCSCNHGHQLDADEKTCIALDDEQFEEEEEVLDILRFPGLLVQSSPQPLPYYAPSLTASYEDENNDEEDQEAEGEFQGLTALQRVVCLDGTFGPDCSLSCEDCMNGGRCQEGESGCVCPEGWNGILCNESNTQRTGMDQQAPLGCLKGFFGKDCKRKCHCAKDGHCHRVYGACICDLGRYGRFCHLSCPRGTYGAGCSLECQCVEENTLDCSAKNGSCTCKSGYQGNRCQEGTIQ", "length": 572, "header": "tr|A0A9J7H909-1|A0A9J7H909_CRIGR Isoform 1 of EGF-like and EMI domain-containing protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100765263 PE=3 SV=1 CANONICAL=A0A9J7H909-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H964-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H909/entry#A0A9J7H964-1", "sequence": { "sequence": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307882", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307882" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9S5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100752571", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5", "locus": {} } ], "crossref": [ { "id": "A0A9J7H9S5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H9S5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07416", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07416", "database": "CDD", "categories": [ "Protein 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00149", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00149", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307882", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307882", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H925", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H925", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H925-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H925-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9S5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLFGARLLESESGVNAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAMPSDANLNSINKALASETNGTDSNGSNSSNIQ", "length": 508, "header": "tr|A0A9J7H9S5-1|A0A9J7H9S5_CRIGR Isoform 1 of Serine/threonine-protein phosphatase OS=Cricetulus griseus OX=10029 GN=LOC100752571 PE=3 SV=1 CANONICAL=A0A9J7H9S5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H925-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5/entry#A0A9J7H925-1", "sequence": { "sequence": "MRPWDACLPVHVIAAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAMPSDANLNSINKALASETNGTDSNGSNSSNIQ", "length": 506, "header": "tr|A0A9J7H925-1|A0A9J7H9S5_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase OS=Cricetulus griseus OX=10029 GN=LOC100752571 PE=3 SV=1 CANONICAL=A0A9J7H9S5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5/entry#A0A9J7H9S5-1", "sequence": { "sequence": "MKLFGARLLESESGVNAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAMPSDANLNSINKALASETNGTDSNGSNSSNIQ", "length": 508, "header": "tr|A0A9J7H9S5-1|A0A9J7H9S5_CRIGR Isoform 1 of Serine/threonine-protein phosphatase OS=Cricetulus griseus OX=10029 GN=LOC100752571 PE=3 SV=1 CANONICAL=A0A9J7H9S5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H925", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H925" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H925", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H925" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "calcineurin-mediated signaling", "id": "GO:0097720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097720", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9S5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin-dependent protein phosphatase activity", "id": "GO:0033192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033192", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9S5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9S5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9S5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 503, "end_pos": 505, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GV48-1", "G3GWQ6-1", "G3H060-1", "G3H9Q0-1", "G3H7Z6-1", "G3I157-1", "G3HCQ6-1", "A0A8C2MA30-1", "G3HMJ7-1", "G3I434-1", "G3H622-1", "G3HKY7-1", "G3GRD1-1", "G3I4H5-1", "G3H8H2-1", "A0A9J7F890-1", "A0A8C2MW37-1", "A0A061I6V7-1", "A0A9J7GBP5-1", "A0A9J7JFN8-1", "A0A9J7G7W0-1", "A0A9J7GE78-1", "A0A061HVT3-1", "A0A061HX98-1", "A0A3L7HX32-1", "A0A8C2LYQ8-1", "A0A8C2M5N0-1", "A0A9J7JBH1-1", "A0A9J7EY47-1", "A0A8C2LGL9-1", "A0A8C2LVB9-1", "A0A8C2QH88-1", "A0A9J7F130-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FXD0-1", "A0A9J7G243-1", "A0A9J7GEM4-1", "A0A9J7G1B8-1", "A0A9J7K1J8-1", "A0A9J7K5S1-1", "A0A9J7EZL1-1", "A0A8C2QCP2-1", "A0A8C2LTP5-1", "A0A8C2N2E5-1", "A0A8C2QBZ1-1", "A0A3L7HBF4-1", "A0A9J7GK96-1", "A0A8C2LI03-1", "A0A9J7G0U7-1", "A0A9J7GD33-1", "A0A9J7H9S5-1", "A0A9J7HCJ8-1", "A0A9J7GJY7-1", "A0A9J7JYW1-1", "A0A3L7I513-1", "A0A9J7FKB3-1", "A0A8C2LGY1-1", "A0A3L7HEM4-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GV48-1", "G3GWQ6-1", "G3H060-1", "G3H9Q0-1", "G3H622-1", "G3HKY7-1", "G3H7Z6-1", "G3I157-1", "G3HCQ6-1", "A0A8C2MA30-1", "G3HMJ7-1", "A0A8C2MF90-1", "A0A9J7GX39-1", "G3I434-1", "G3GRD1-1", "G3I4H5-1", "G3H8H2-1", "A0A9J7F890-1", "A0A8C2MW37-1", "A0A061I6V7-1", "A0A9J7GBP5-1", "A0A9J7JFN8-1", "A0A9J7G7W0-1", "A0A9J7GE78-1", "A0A061HX98-1", "A0A3L7HEJ5-1", "A0A3L7HX32-1", "A0A8C2LYQ8-1", "A0A8C2M5N0-1", "A0A9J7JBH1-1", "A0A8C2ME51-1", "A0A8C2MTQ0-1", "A0A3L7IJ01-1", "A0A9J7EY47-1", "A0A8C2LGL9-1", "A0A8C2LVB9-1", "A0A8C2QH88-1", "A0A9J7F130-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FXD0-1", "A0A9J7G243-1", "A0A9J7GEM4-1", "A0A9J7G1B8-1", "A0A9J7K1J8-1", "A0A9J7K5S1-1", "A0A9J7EZL1-1", "A0A9J7F6Q7-1", "A0A8C2N2E5-1", "A0A8C2LTP5-1", "A0A8C2QBZ1-1", "A0A8C2QCP2-1", "A0A3L7HBF4-1", "A0A3L7HC66-1", "A0A9J7GK96-1", "A0A8C2LI03-1", "A0A9J7G0U7-1", "A0A9J7GD33-1", "A0A9J7H9S5-1", "A0A9J7HCJ8-1", "A0A9J7GJY7-1", "A0A9J7JXQ8-1", "A0A9J7JYW1-1", "A0A9J7FKB3-1", "A0A8C2LGY1-1", "A0A3L7HEM4-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HVT3", "gene_name": "Ppm1k", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.52", "activity": "O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + H2O = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.52", "activity": "", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] } ] }, { "uniprot_ac": "A0A061HX98", "gene_name": "Dusp9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] } ] }, { "uniprot_ac": "A0A061I6V7", "gene_name": "Pgam5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061I6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6V7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061I6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6V7" } ] } ] }, { "uniprot_ac": "A0A3L7HBF4", "gene_name": "Cpped1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBF4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBF4" } ] } ] }, { "uniprot_ac": "A0A3L7HC66", "gene_name": "Ppp6c", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HC66" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HC66" } ] } ] }, { "uniprot_ac": "A0A3L7HEJ5", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] } ] }, { "uniprot_ac": "A0A3L7HEM4", "gene_name": "Ctdspl2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEM4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEM4" } ] } ] }, { "uniprot_ac": "A0A3L7HX32", "gene_name": "Dusp8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] } ] }, { "uniprot_ac": "A0A3L7I513", "gene_name": "Pdxp", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] } ] }, { "uniprot_ac": "A0A3L7IJ01", "gene_name": "Ppp2cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7IJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJ01" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7IJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJ01" } ] } ] }, { "uniprot_ac": "A0A8C2LGL9", "gene_name": "Ppp1cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LGL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGL9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LGL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGL9" } ] } ] }, { "uniprot_ac": "A0A8C2LGY1", "gene_name": "Ppp1ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LGY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGY1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LGY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGY1" } ] } ] }, { "uniprot_ac": "A0A8C2LI03", "gene_name": "Ctdsp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI03" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI03" } ] } ] }, { "uniprot_ac": "A0A8C2LTP5", "gene_name": "LOC100752571", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LTP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTP5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LTP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTP5" } ] } ] }, { "uniprot_ac": "A0A8C2LVB9", "gene_name": "Dusp22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] } ] }, { "uniprot_ac": "A0A8C2LYQ8", "gene_name": "Ppm1l", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYQ8" } ] } ] }, { "uniprot_ac": "A0A8C2M5N0", "gene_name": "Ppp1cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2M5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5N0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2M5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5N0" } ] } ] }, { "uniprot_ac": "A0A8C2MA30", "gene_name": "Phlpp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MA30" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MA30" } ] } ] }, { "uniprot_ac": "A0A8C2ME51", "gene_name": "Ppm1g", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2ME51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ME51" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2ME51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ME51" } ] } ] }, { "uniprot_ac": "A0A8C2MF90", "gene_name": "Ssh2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MF90" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MF90" } ] } ] }, { "uniprot_ac": "A0A8C2MTQ0", "gene_name": "Ssh1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTQ0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTQ0" } ] } ] }, { "uniprot_ac": "A0A8C2MW37", "gene_name": "Ppp3cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ] } ] }, { "uniprot_ac": "A0A8C2N2E5", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] } ] }, { "uniprot_ac": "A0A8C2QBZ1", "gene_name": "Ctdspl", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QBZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QBZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ] } ] }, { "uniprot_ac": "A0A8C2QCP2", "gene_name": "Dusp28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] } ] }, { "uniprot_ac": "A0A8C2QH88", "gene_name": "Dusp12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": 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"O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] } ] }, { "uniprot_ac": "A0A9J7EZL1", "gene_name": "LOC113830718", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] } ] }, { "uniprot_ac": "A0A9J7F130", "gene_name": "LOC100769947", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F130" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F130" } ] } ] }, { "uniprot_ac": "A0A9J7F6Q7", "gene_name": "LOC103164195", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F6Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6Q7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F6Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6Q7" } ] } ] }, { "uniprot_ac": "A0A9J7F890", "gene_name": "Ctdsp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F890" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F890" } ] } ] }, { "uniprot_ac": "A0A9J7FKB3", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] } ] }, { "uniprot_ac": "A0A9J7FMB0", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] } ] }, { "uniprot_ac": "A0A9J7FWJ6", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FXD0", "gene_name": "Ppm1f", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXD0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXD0" } ] } ] }, { "uniprot_ac": "A0A9J7G0U7", "gene_name": "Pptc7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ] } ] }, { "uniprot_ac": "A0A9J7G1B8", "gene_name": "Phlpp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B8" } ] } ] }, { "uniprot_ac": "A0A9J7G243", "gene_name": "Ppm1a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G243" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G243" } ] } ] }, { "uniprot_ac": "A0A9J7G7W0", "gene_name": "Ptpmt1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.27", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] } ] }, { "uniprot_ac": "A0A9J7GBP5", "gene_name": "Rpap2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GBP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GBP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP5" } ] } ] }, { "uniprot_ac": "A0A9J7GD33", "gene_name": "Ublcp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GD33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GD33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ] } ] }, { "uniprot_ac": "A0A9J7GE78", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] } ] }, { "uniprot_ac": "A0A9J7GEM4", "gene_name": "Ppm1e", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEM4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEM4" } ] } ] }, { "uniprot_ac": "A0A9J7GJY7", "gene_name": "Ppef1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJY7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJY7" } ] } ] }, { "uniprot_ac": "A0A9J7GK96", "gene_name": "Ppm1n", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK96" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK96" } ] } ] }, { "uniprot_ac": "A0A9J7GX39", "gene_name": "Ssh3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GX39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX39" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GX39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX39" } ] } ] }, { "uniprot_ac": "A0A9J7H9S5", "gene_name": "LOC100752571", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7H9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5" } ] } ] }, { "uniprot_ac": "A0A9J7HCJ8", "gene_name": "Ppp3cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7HCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7HCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JBH1", "gene_name": "Cdc14a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] } ] }, { "uniprot_ac": "A0A9J7JFN8", "gene_name": "Epm2a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] } ] }, { "uniprot_ac": "A0A9J7JXQ8", "gene_name": "Ppp2ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXQ8" } ] } ] }, { "uniprot_ac": "A0A9J7JYW1", "gene_name": "Ctdnep1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JYW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYW1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JYW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYW1" } ] } ] }, { "uniprot_ac": "A0A9J7K1J8", "gene_name": "LOC100761879", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7K1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1J8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7K1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1J8" } ] } ] }, { "uniprot_ac": "A0A9J7K5S1", "gene_name": "Ilkap", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7K5S1", "database": "UniProtKB", "url": 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Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305543", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305543" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H927", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H927" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100756676", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H927", "locus": {} } ], "crossref": [ { "id": "A0A9J7H927", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H927", "database": "AlphaFoldDB", "categories": [] }, { "id": "100756676", "url": "https://www.ncbi.nlm.nih.gov/gene/100756676", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45984:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45984:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13877", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13877", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305543", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305543", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H927", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H927", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H927-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H927-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHWVTSIFLYHVSAMAAKDCPSLWSFGTTKTFKIPVEHLDFKYIEKCSDVKHLEKILCVLRSGEEGYYPELTEFCEKRLMGLAPGSRALRKDKPAATASSFTAEEWEKIDSDLKTWVSEIKREENTRYFHDPETYQEVEDHLPPVRGSDDSAHRGKETYSKNKPAKKKVPRDYAEWDKFDVEKECSKIDEDYKEKMIVDNKAHLSKIETKIDTAGLTEKEKSFLADREKGKGNEAFHAGDYEEAIMYYTRSLSALPTVSAYNNRAQAAIKLQQWNSAVQDCEKALKLEPGNMKALLRRATAYKHQNKLQEAAEDLKVVLSVEPHNDMARKILSEIESDLKKPESASEPQTQGKRMVIEEVESSGDEGEKQSRDKPEDGGGDTAGAMGNNIPRKLLGRSEGSRRSRRGRTPTPGPRAEQRGGPREPVATTTSGGGDTPQPGEPRAPDGPGDLRSRGNELFRCGQFAQAAAQYSAAIAQLEPAGGASVDELSILYSNRAACYLKEGNCSCCIQDCNRALELCPFSVKPLLRRAMAYETSEKYRKAYVDYKTVLQIDYGIQLASSSINRLTNILMELDGPKWREKLPPTPVVPSTSEPLPPAAAETPDREPQPSGCPAGITDEKLFQVLKEEGNQLVRDKNYKDAISKYSECLKINSQECAIYTNRALCYLKLGQFEEAKLDCDQALQIDGENEKACYRLALAQEGLKNRQESLADPGQALLHPGAGEAKMGPQEATRDPDAKNGTAPTSKGRERRRIQVQEVNESSDEEPERPAEASAASPPASEGAGNRGSAECSPKLEVSKPSNAYEFGQVLNAICTKKDAEACAHLLAITAPKDLPVWLSNKLEGDMFLLLIQSLKSHLVAKDPSLVYEHLLHLSKAQRFKMTLTLINGGQKEQIVQLLDSLSHAPTDRFTVEDVQALRRQYEL", "length": 925, "header": "tr|A0A9J7H927-1|A0A9J7H927_CRIGR Isoform 1 of Sperm-associated antigen 1 OS=Cricetulus griseus OX=10029 GN=LOC100756676 PE=4 SV=1 CANONICAL=A0A9J7H927-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H927-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H927/entry#A0A9J7H927-1", "sequence": { "sequence": "MHWVTSIFLYHVSAMAAKDCPSLWSFGTTKTFKIPVEHLDFKYIEKCSDVKHLEKILCVLRSGEEGYYPELTEFCEKRLMGLAPGSRALRKDKPAATASSFTAEEWEKIDSDLKTWVSEIKREENTRYFHDPETYQEVEDHLPPVRGSDDSAHRGKETYSKNKPAKKKVPRDYAEWDKFDVEKECSKIDEDYKEKMIVDNKAHLSKIETKIDTAGLTEKEKSFLADREKGKGNEAFHAGDYEEAIMYYTRSLSALPTVSAYNNRAQAAIKLQQWNSAVQDCEKALKLEPGNMKALLRRATAYKHQNKLQEAAEDLKVVLSVEPHNDMARKILSEIESDLKKPESASEPQTQGKRMVIEEVESSGDEGEKQSRDKPEDGGGDTAGAMGNNIPRKLLGRSEGSRRSRRGRTPTPGPRAEQRGGPREPVATTTSGGGDTPQPGEPRAPDGPGDLRSRGNELFRCGQFAQAAAQYSAAIAQLEPAGGASVDELSILYSNRAACYLKEGNCSCCIQDCNRALELCPFSVKPLLRRAMAYETSEKYRKAYVDYKTVLQIDYGIQLASSSINRLTNILMELDGPKWREKLPPTPVVPSTSEPLPPAAAETPDREPQPSGCPAGITDEKLFQVLKEEGNQLVRDKNYKDAISKYSECLKINSQECAIYTNRALCYLKLGQFEEAKLDCDQALQIDGENEKACYRLALAQEGLKNRQESLADPGQALLHPGAGEAKMGPQEATRDPDAKNGTAPTSKGRERRRIQVQEVNESSDEEPERPAEASAASPPASEGAGNRGSAECSPKLEVSKPSNAYEFGQVLNAICTKKDAEACAHLLAITAPKDLPVWLSNKLEGDMFLLLIQSLKSHLVAKDPSLVYEHLLHLSKAQRFKMTLTLINGGQKEQIVQLLDSLSHAPTDRFTVEDVQALRRQYEL", "length": 925, "header": "tr|A0A9J7H927-1|A0A9J7H927_CRIGR Isoform 1 of Sperm-associated antigen 1 OS=Cricetulus griseus OX=10029 GN=LOC100756676 PE=4 SV=1 CANONICAL=A0A9J7H927-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 411, "start_aa": "Thr", "end_pos": 411, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr411", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H927", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H927" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H927", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H927" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756676", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756676", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H927", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H927" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H927", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H927" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H927", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H927" } ], "pmid": "" }, { "name": "dynein axonemal particle", "id": "GO:0120293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120293", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H927", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H927" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H927", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H927" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" }, { "start_pos": 741, "end_pos": 743, "annotation": "n_glycosylation_sequon" }, { "start_pos": 761, "end_pos": 763, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H927" }, { "id": "PF13877", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13877" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNA-polymerase II-associated protein 3-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 801, "end_pos": 893, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 411 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 505, "end_pos": 507 }, { "start_pos": 741, "end_pos": 743 }, { "start_pos": 761, "end_pos": 763 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": 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"total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7H930-1", "uniprot_ac": "A0A9J7H930", "uniprot_id": "A0A9J7H930_CRIGR", "mass": { "chemical_mass": 36994.0, "monoisotopic_mass": 36994.0 }, "refseq": { "ac": "XP_035292799", "name": "olfactory receptor 6C76-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292799" }, "gene_names": [ { "name": "LOC100769803", "type": "recommended", "evidence": [ { "id": "A0A9J7H930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H930" } ] }, { "name": "LOC100769803", "type": "synonym", "evidence": [ { "id": "XP_035292799", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292799" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7H930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H930/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 6C76-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035292799", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292799" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615493.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035292799", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292799" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H930", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H930" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100769803", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H930", "locus": {} } ], "crossref": [ { "id": "A0A9J7H930", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H930", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769803", "url": "https://www.ncbi.nlm.nih.gov/gene/100769803", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769803", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769803", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H930", "url": "https://www.orthodb.org/?gene=A0A9J7H930", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JAE5", "url": "https://www.orthodb.org/?gene=A0A9J7JAE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035292799", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292799", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H930", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H930", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H930-1", "url": 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Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 57% of CDS bases internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304933", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304933" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H949", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H949" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100750729", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H949", "locus": {} } ], "crossref": [ { "id": "cd14337", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14337", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100750729", "url": "https://www.ncbi.nlm.nih.gov/gene/100750729", "database": "GeneID", "categories": [ 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non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=LOC100750729 PE=4 SV=1 CANONICAL=A0A9J7H949-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7H949" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H949", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H949" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H949", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H949" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H949", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H949" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"A0A8C2LPE9-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A8C2M7I3-1", "A0A8C2MBI9-1", "A0A9J7JQZ1-1", "A0A8C2N3I1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7GBL6-1", "A0A9J7H8W5-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7H540-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H949-1", "A0A9J7GQY0-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP 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"ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] } ] }, { "uniprot_ac": "A0A8C2N185", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": 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"id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] } ] }, { "uniprot_ac": "A0A9J7F1D2", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F821", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] } ] }, { "uniprot_ac": "A0A9J7F8T0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] } ] }, { "uniprot_ac": "A0A9J7G8N4", "gene_name": "Sgk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] } ] }, { "uniprot_ac": "A0A9J7G969", "gene_name": "LOC100754771", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] } ] }, { "uniprot_ac": "A0A9J7G9D1", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBI2", "gene_name": "LOC100771767", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] } ] }, { "uniprot_ac": "A0A9J7GBL6", "gene_name": "Ttbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] } ] }, { "uniprot_ac": "A0A9J7GD76", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] } ] }, { "uniprot_ac": "A0A9J7GES8", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP 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"https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] } ] }, { "uniprot_ac": "A0A9J7GJE4", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] } ] }, { "uniprot_ac": "A0A9J7GK55", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] } ] }, { "uniprot_ac": "A0A9J7GLT3", "gene_name": "LOC113838166", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] } ] }, { "uniprot_ac": "A0A9J7GMF3", "gene_name": "LOC103158537", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] } ] }, { "uniprot_ac": "A0A9J7GQ42", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] } ] }, { "uniprot_ac": "A0A9J7GQY0", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] } ] }, { "uniprot_ac": "A0A9J7GR05", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] } ] }, { "uniprot_ac": "A0A9J7GR29", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] } ] }, { "uniprot_ac": "A0A9J7GRB5", "gene_name": "LOC113838167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRB5" } ] } ] }, { "uniprot_ac": "A0A9J7GRC1", "gene_name": "LOC100764806", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRC1" } ] } ] }, { "uniprot_ac": "A0A9J7GT89", "gene_name": "LOC100774420", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] } ] }, { 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GX76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GX76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX76" } ] } ] }, { "uniprot_ac": "A0A9J7GY39", "gene_name": "Akt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] } ] }, { "uniprot_ac": "A0A9J7GZH5", "gene_name": "Ripk4", "activity": [ { "ec_number": "2.7.11.1", "activity": 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"ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "A0A9J7H3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E2" } ] } ] }, { "uniprot_ac": "A0A9J7H3L8", "gene_name": "Csnk2a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] } ] }, { "uniprot_ac": "A0A9J7H3M5", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] } ] }, { "uniprot_ac": "G3IN30", "gene_name": "Plk1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] } ] }, { "uniprot_ac": "O55076", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] } ] }, { "uniprot_ac": "P25321", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P25321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25321" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P25321", "database": "UniProtKB", 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"database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755544", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755544", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H9A3", "url": "https://www.orthodb.org/?gene=A0A9J7H9A3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10796", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10796", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10796:SF36", 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Isoform 1 of Patched domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Ptchd1 PE=3 SV=1 CANONICAL=A0A9J7H9A3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H9A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9A3/entry#A0A9J7H9A3-1", "sequence": { "sequence": 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Isoform 1 of Patched domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Ptchd1 PE=3 SV=1 CANONICAL=A0A9J7H9A3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"https://www.uniprot.org/uniprotkb/A0A9J7H9A3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cognition", "id": "GO:0050890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050890", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9A3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9A3" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9A3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9A3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, 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"eco_id": "ECO_0000259", "start_pos": 313, "end_pos": 472, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 178, "end_pos": 180 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 364, "end_pos": 366 }, { "start_pos": 371, "end_pos": 373 }, { "start_pos": 596, "end_pos": 598 }, { "start_pos": 613, "end_pos": 615 }, { "start_pos": 644, "end_pos": 646 }, { "start_pos": 653, "end_pos": 655 }, { "start_pos": 77, "end_pos": 79 }, { "start_pos": 807, "end_pos": 809 }, { "start_pos": 863, "end_pos": 865 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 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This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305042", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305042" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9B0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100764224", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9B0", "locus": {} } ], "crossref": [ { "id": "A0A9J7H9B0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H9B0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100764224", "url": "https://www.ncbi.nlm.nih.gov/gene/100764224", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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"function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 5% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305660", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305660" } ] }, { "annotation": "Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9B1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9B1#function" }, { "database": "UniProtKB", "id": "ARBA00035003", "url": "https://www.uniprot.org/uniprotkb/ARBA00035003#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9B1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9B1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306407" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9C5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100769684", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9C5", "locus": {} } ], "crossref": [ { "id": "A0A9J7H9C5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H9C5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769684", "url": "https://www.ncbi.nlm.nih.gov/gene/100769684", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769684", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769684", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FPYCDLR", "url": "https://omabrowser.org/oma/group/FPYCDLR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H9C5", "url": "https://www.orthodb.org/?gene=A0A9J7H9C5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306407", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H9C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9C5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9C5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVRWLNQSSTYDFILLGIFSHNPTDHLLFSVVMLVFTVALCGNGLLIFLIYTDPRLHTPMYLFLSQLSLMDLMLVCTNVPKMAINFLSGRKSISFVGCSIQIGLFVCLVGSEGLLLGLMAYDRYVAISHPLHYPVLMNQKVCLQIVGSSWAFGIVDGLVQMLVVMSFPYCNLREVDHFFCEMLSLLKLACVDTSLFEKVVFVCCVFMLLFPFSIIVASYARILGAVLRMHSTQSRKKAMATCSSHLTAVSFFYGAAMFIYLRPRRYRTPSQDKVVSIFYTVLTPMLNPLIYSLRNRDVIGALQKGLDRCRVGSQH", "length": 315, "header": "tr|A0A9J7H9C5-1|A0A9J7H9C5_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100769684 PE=3 SV=1 CANONICAL=A0A9J7H9C5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H9C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9C5/entry#A0A9J7H9C5-1", "sequence": { "sequence": "MVRWLNQSSTYDFILLGIFSHNPTDHLLFSVVMLVFTVALCGNGLLIFLIYTDPRLHTPMYLFLSQLSLMDLMLVCTNVPKMAINFLSGRKSISFVGCSIQIGLFVCLVGSEGLLLGLMAYDRYVAISHPLHYPVLMNQKVCLQIVGSSWAFGIVDGLVQMLVVMSFPYCNLREVDHFFCEMLSLLKLACVDTSLFEKVVFVCCVFMLLFPFSIIVASYARILGAVLRMHSTQSRKKAMATCSSHLTAVSFFYGAAMFIYLRPRRYRTPSQDKVVSIFYTVLTPMLNPLIYSLRNRDVIGALQKGLDRCRVGSQH", "length": 315, "header": "tr|A0A9J7H9C5-1|A0A9J7H9C5_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100769684 PE=3 SV=1 CANONICAL=A0A9J7H9C5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9C5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9C5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769684", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769684", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A387-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259610", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEIWLNQSSTDDFVLLGIFSHGPADLVLFSAVMIVFMVAICGNILLIFLIYIDPRLHTPMYFFLSQLSLMDLMLVCTNVPQMAVNFLSGRKYISFVGCGIQIGLFVCLVGSEGLLLGLMAYDRYVAITHPLHYPILMSQRVCLQIVGSSWAFGIIDGFTQMVVVMTFPYCGLREVDHFFCEMLSLLKLACIDTSIFENMIFVCCVIMLFLPFSIIVASYARILKAVLHMRSAQAGKKALATCSSHLTAVSLFYGAAMFIYLRPRRYRAPSHDKVVSIFYTVLTPMLNPLIYSLRNREVMGALRKGLDRCRIANQP", "length": 315 }, "evidence": [ { "id": "A0A9J7H9C5", "url": "https://omabrowser.org/oma/group/A0A9J7H9C5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6A837-1", "protein_name": "Olfactory receptor", "gene_name": "Or2v2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMWLNQSFTDDFILLGIFSYSPTDLLLFSVVMLVFTVALCGNVLLILLIYTDPRLHTPMYFFLSQLSLMDLMLVCTNVPKMALNFLSGKKSISFMGCGIQIGLFVCLVGSEGLLLGLMAYDRYVAISHPLHYPVLMNKKVCLQIVGSSWAFGIVDGLVQMVVVMTFPYCSLREVDHFFCEMLSLLKLACMDTSLFEKVVFVCCVFMLLFPFSIIVASYTRILGTVLRMHSAKSQKKALATCSSHLTAVSFFYGAAMFIYLRPRQYRTPSQDKMVSIFYTVLTPMLNPLIYSLRNRDVIGALQKRLDRCRIGSHH", "length": 315 }, "evidence": [ { "id": "A0A9J7H9C5", "url": "https://omabrowser.org/oma/group/A0A9J7H9C5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X8G3-1", "protein_name": "Olfactory receptor", "gene_name": "OR2V2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEIWLNQSSTDDFVLLGIFSHSSTDLVLFSAVMMVFIVALCGNILLIFLIFMDPQLHTPMYFFLSQLSFMDLMLVCTNVPKMAANFLSGRKSISFVGCGMQIGLFVCLVGSEGLLLGLMAYDRYVAISHPLHYPILMSQRVCLQIVGSSWVFGITDGLIQMVVVMTFPYCGLREVDHFFCEMLSLLKLACIDTSIFENVIFACCVFMLFLPFSIIVASYARILRTVLHMHSAQAVRKALATCSSHLTAVFLFYGAAMFIYLRPKRYRAPSHDKVVSVFYTVLTPMLNPLIYSLRNREVMGALRKGLDHCRIVNQH", "length": 315 }, "evidence": [ { "id": "A0A9J7H9C5", "url": "https://omabrowser.org/oma/group/A0A9J7H9C5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96R30-1", "protein_name": "Olfactory receptor 2V2", "gene_name": "OR2V2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METWVNQSYTDGFFLLGIFSHSTADLVLFSVVMAVFTVALCGNVLLIFLIYMDPHLHTPMYFFLSQLSLMDLMLVCTNVPKMAANFLSGRKSISFVGCGIQIGLFVCLVGSEGLLLGLMAYDRYVAISHPLHYPILMNQRVCLQITGSSWAFGIIDGLIQMVVVMNFPYCGLRKVNHFFCEMLSLLKLACVDTSLFEKVIFACCVFMLLFPFSIIVASYAHILGTVLQMHSAQAWKKALATCSSHLTAVTLFYGAAMFIYLRPRHYRAPSHDKVASIFYTVLTPMLNPLIYSLRNREVMGALRKGLDRCRIGSQH", "length": 315 }, "evidence": [ { "id": "A0A9J7H9C5", "url": "https://omabrowser.org/oma/group/A0A9J7H9C5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9C5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9C5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9C5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7H9C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9C5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": 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NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. 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{ "name": "probable tRNA methyltransferase 9B", "type": "synonym", "evidence": [ { "id": "XP_035308056", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308056" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N5#function" }, { "database": "UniProtKB", "id": "ARBA00025038", "url": "https://www.uniprot.org/uniprotkb/ARBA00025038#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC103160806", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N5", "locus": {} } ], "crossref": [ { "id": "A0A9J7H9N5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7H9N5", "database": "AlphaFoldDB", "categories": [] }, { "id": "103160806", "url": "https://www.ncbi.nlm.nih.gov/gene/103160806", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103160806", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103160806", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR11961", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11961", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307728", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H9N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNVEKDKKILVQKCAQCLTVEKGGNHKPGPNLHGVFGRKTGEDSPIQMGEDTLMEHLENPKKYIPGTKMSFAGIKKEERVDLIAYLKKATNV", "length": 93, "header": "tr|A0A9J7H9N5-1|A0A9J7H9N5_CRIGR Isoform 1 of Cytochrome c-like OS=Cricetulus griseus OX=10029 GN=LOC103160806 PE=3 SV=1 CANONICAL=A0A9J7H9N5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H9N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9N5/entry#A0A9J7H9N5-1", "sequence": { "sequence": "MGNVEKDKKILVQKCAQCLTVEKGGNHKPGPNLHGVFGRKTGEDSPIQMGEDTLMEHLENPKKYIPGTKMSFAGIKKEERVDLIAYLKKATNV", "length": 93, "header": "tr|A0A9J7H9N5-1|A0A9J7H9N5_CRIGR Isoform 1 of Cytochrome c-like OS=Cricetulus griseus OX=10029 GN=LOC103160806 PE=3 SV=1 CANONICAL=A0A9J7H9N5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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] }, { "uniprot_canonical_ac": "A0A9J7H9P3-1", "uniprot_ac": "A0A9J7H9P3", "uniprot_id": "A0A9J7H9P3_CRIGR", "mass": { "chemical_mass": 38645.0, "monoisotopic_mass": 38645.0 }, "refseq": { "ac": "XP_035307304", "name": "saoe class I histocompatibility antigen, A alpha chain-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307304" }, "gene_names": [ { "name": "LOC100751667", "type": "recommended", "evidence": [ { "id": "A0A9J7H9P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P3" } ] }, { "name": "LOC100751667", "type": "synonym", "evidence": [ { "id": "XP_035307304", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307304" } ] } ], "protein_names": [ { "name": "Saoe class I histocompatibility antigen, A alpha chain-like", "type": "synonym", "evidence": [ { "id": "A0A9J7H9P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P3/entry#names_and_taxonomy" } ] }, { "name": "saoe class I histocompatibility antigen, A alpha chain-like", "type": "synonym", "evidence": [ { "id": "XP_035307304", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307304" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307304", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307304" } ] }, { "annotation": "Involved in the presentation of foreign antigens to the immune system.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P3#function" }, { "database": "UniProtKB", "id": "ARBA00002297", "url": "https://www.uniprot.org/uniprotkb/ARBA00002297#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100751667", "url": 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Classification" ] }, { "id": "cge:100751667", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751667", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H9P3", "url": "https://www.orthodb.org/?gene=A0A9J7H9P3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16675:SF169", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16675:SF169", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307304", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307304", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H9P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSAVPHTLLLLLAAALPPTQACAGSHSLRYFSTAFHNPDNNKPRVMVVGYVDNTEILSFDSDEASQQVKPRVPFMAQDREHLEELTRLGRRVLIVGRIELRILFSYRSQRENGSLTIQELCGCDVGPDHRLLHGYKQIAYEGQDYISLTEDMRSWTAVDIKEAQITRRKWEASGFAKLFRSFFEGSCVAWLLRYLDKGKEMLLRAEPPKTNVTHHPRPEGEATLKCWALGFYPADITLIWQKEEEDLTQDMDLIETRPAGDGTFQKWAAVVVPSGEEQRYTCHVNHEGLPEPLILRWEPPPSPTPPIMGIVAGLVLLGVLVTGAVAAIVMRKNTEMEKDVVR", "length": 343, "header": "tr|A0A9J7H9P3-1|A0A9J7H9P3_CRIGR Isoform 1 of Saoe class I histocompatibility antigen, A alpha chain-like OS=Cricetulus griseus OX=10029 GN=LOC100751667 PE=3 SV=1 CANONICAL=A0A9J7H9P3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H9P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9P3/entry#A0A9J7H9P3-1", "sequence": { "sequence": "MGSAVPHTLLLLLAAALPPTQACAGSHSLRYFSTAFHNPDNNKPRVMVVGYVDNTEILSFDSDEASQQVKPRVPFMAQDREHLEELTRLGRRVLIVGRIELRILFSYRSQRENGSLTIQELCGCDVGPDHRLLHGYKQIAYEGQDYISLTEDMRSWTAVDIKEAQITRRKWEASGFAKLFRSFFEGSCVAWLLRYLDKGKEMLLRAEPPKTNVTHHPRPEGEATLKCWALGFYPADITLIWQKEEEDLTQDMDLIETRPAGDGTFQKWAAVVVPSGEEQRYTCHVNHEGLPEPLILRWEPPPSPTPPIMGIVAGLVLLGVLVTGAVAAIVMRKNTEMEKDVVR", "length": 343, "header": "tr|A0A9J7H9P3-1|A0A9J7H9P3_CRIGR Isoform 1 of Saoe class I histocompatibility antigen, A alpha chain-like OS=Cricetulus griseus OX=10029 GN=LOC100751667 PE=3 SV=1 CANONICAL=A0A9J7H9P3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", 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Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307758", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307758" } ] }, { "annotation": "Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9Q6#function" }, { "database": "UniProtKB", "id": "RU311113", "url": "https://www.uniprot.org/uniprotkb/RU311113#function" }, { "database": "UniProtKB", "id": "ARBA00002449", "url": "https://www.uniprot.org/uniprotkb/ARBA00002449#function" }, { "database": "UniProtKB", "id": "A0A9J7HDU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDU9#function" }, { "database": "UniProtKB", "id": "A0A9J7J7V2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7V2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9Q6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H9Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9Q6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:118237705", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118237705", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1L1S0Y9-1", "protein_name": "Cyclin-dependent kinases regulatory subunit", "gene_name": "CKS1B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAHKQIYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHLMSESEWRNLGVQQSQGWVHYMIHEPEPHILLFRRPLPKKPEK", "length": 79 }, "evidence": [ { "id": "A0A9J7H9Q6", "url": "https://omabrowser.org/oma/group/A0A9J7H9Q6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A480C3W8-1", 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This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306619", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306619" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA09", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA09" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ascl1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA09", "locus": {} } ], "crossref": [ { "id": "A0A9J7HA09", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HA09", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19742", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19742", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772145", "url": "https://www.ncbi.nlm.nih.gov/gene/100772145", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772145", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772145", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HA09", "url": "https://www.orthodb.org/?gene=A0A9J7HA09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13935", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13935", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13935:SF153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13935:SF153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306619", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306619", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HA09", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA09-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGSGKMESGAGQQPQPPQPFLPPAACFFATAAAAAAAAAAQSAQQQQQQQQQQQPPPQPQQAPQLSPVADGQPSGGGHKSAAKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSNDMNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF", "length": 236, "header": "tr|A0A9J7HA09-1|A0A9J7HA09_CRIGR Isoform 1 of Achaete-scute homolog 1 OS=Cricetulus griseus OX=10029 GN=Ascl1 PE=4 SV=1 CANONICAL=A0A9J7HA09-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HA09-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA09/entry#A0A9J7HA09-1", "sequence": { "sequence": "MEGSGKMESGAGQQPQPPQPFLPPAACFFATAAAAAAAAAAQSAQQQQQQQQQQQPPPQPQQAPQLSPVADGQPSGGGHKSAAKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSNDMNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF", "length": 236, "header": "tr|A0A9J7HA09-1|A0A9J7HA09_CRIGR Isoform 1 of Achaete-scute homolog 1 OS=Cricetulus griseus OX=10029 GN=Ascl1 PE=4 SV=1 CANONICAL=A0A9J7HA09-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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}, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HA39-1", "uniprot_ac": "A0A9J7HA39", "uniprot_id": "A0A9J7HA39_CRIGR", "mass": { "chemical_mass": 108629.0, "monoisotopic_mass": 108629.0 }, "refseq": { "ac": "XP_035307579", "name": "peroxisome biogenesis factor 6 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307579" }, "gene_names": [ { "name": "Pex6", "type": "recommended", "evidence": [ { "id": "A0A9J7HA39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ] }, { "name": "Pex6", "type": "synonym", "evidence": [ { "id": "XP_035307579", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307579" } ] } ], "protein_names": [ { "name": "Peroxisomal ATPase PEX6", "type": "recommended", "evidence": [ { "id": "A0A9J7HA39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39/entry#names_and_taxonomy" } ] }, { "name": "Peroxin-6", "type": "synonym", "evidence": [ { "id": "A0A9J7HA39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39/entry#names_and_taxonomy" } ] }, { "name": "Peroxisomal biogenesis factor 6", "type": "synonym", "evidence": [ { "id": "A0A9J7HA39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39/entry#names_and_taxonomy" } ] }, { "name": "peroxisome biogenesis factor 6 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035307579", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307579" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307579", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307579" } ] }, { "annotation": "Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling. Specifically recognizes PEX5 monoubiquitinated at 'Cys-11', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel. Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39#function" }, { "database": "UniProtKB", "id": "ARBA00057209", "url": "https://www.uniprot.org/uniprotkb/ARBA00057209#function" }, { "database": "UniProtKB", "id": "A0A9J7J8N2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8N2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pex6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39", "locus": {} } ], "crossref": [ { "id": "A0A9J7HA39", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HA39", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19481", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19481", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19527", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19527", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773621", "url": "https://www.ncbi.nlm.nih.gov/gene/100773621", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050168", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050168", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773621", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773621", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HA39", "url": "https://www.orthodb.org/?gene=A0A9J7HA39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23077", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23077", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23077:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23077:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25394", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25394", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25395", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25395", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307579", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307579", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA39-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8N2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8N2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALAVLRVLDPFPAETPPLAVLLPPGGPWPATGLGLVLALRPASESPAGPALLVAALEGPGSQNGQRGPGPPQLLVSRALLRLLALGPGARVRARPVRRPPALGWALLGSAPGPGPGPRVGPLLVRRGESLPVPGSRVLETRPALQGLLGPGTRLAVTELRGRAKLGPESTQHSRLPPPPVASSFAVSHAVRQLKGVLGGTGDALGVTRSCLRGLGLFQGEWVWVARVGEFPNTSQPHLAKVQLLEPRWDLSERLGPSSGQLGEPLADGLVFVPATLAFNLGCDPLEVGELRIQRYLEGSIIPEDRGSCSLMSGPPFARELHIEIVSSPHYSANGDYDHVLYRHFHTPRVVQEGDVLCVPTVGQVEILEGSPEKLPRLSASSCDLCQVRHPARNAWLTFVNIQSFVLIGTWCFLWWREVFFKVKKAVGEAPDGPASAFLADTTHTSLYMAGSALSRVPLLPSGRSTPWDSLSPPGLEALVNELCAILKPHLQPGGTLLTGTSCVLLQGPPGSGKTTAVTAACSRLGLHLLKVPCYSLCADSSGAVETKLQAAFSRARRCRPAVLLLTAIDLLGRDRDGLDEDARVVATLRHLLLDEDPVSNCPPLMVVATTSRAQDLPTDVHTAFPHELEVPVLSEEQRLSVLQALTAHLPLGQEVNLLQLARRCAGFVVGDLYALLTHTSRVACARIRASGLAGGLSEEDEGELCAAGFPLLAEDFGQALDQLQTAHSQAVGAPKIPSVSWHDVGGLQDVKKEILETIQLPLEHPELLSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGASEDRASQLRVLSAITRKFKLEASVSLVNVLDRCPPQLTGADLYSLCSDAMTTALKRRVRDLEEGLEMGSSALLLTMEDLLQAAARLQPSVSEQELLRYKRIQRKFAAC", "length": 1018, "header": "tr|A0A9J7HA39-1|A0A9J7HA39_CRIGR Isoform 1 of Peroxisomal ATPase PEX6 OS=Cricetulus griseus OX=10029 GN=Pex6 PE=3 SV=1 CANONICAL=A0A9J7HA39-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HA39-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39/entry#A0A9J7HA39-1", "sequence": { "sequence": "MALAVLRVLDPFPAETPPLAVLLPPGGPWPATGLGLVLALRPASESPAGPALLVAALEGPGSQNGQRGPGPPQLLVSRALLRLLALGPGARVRARPVRRPPALGWALLGSAPGPGPGPRVGPLLVRRGESLPVPGSRVLETRPALQGLLGPGTRLAVTELRGRAKLGPESTQHSRLPPPPVASSFAVSHAVRQLKGVLGGTGDALGVTRSCLRGLGLFQGEWVWVARVGEFPNTSQPHLAKVQLLEPRWDLSERLGPSSGQLGEPLADGLVFVPATLAFNLGCDPLEVGELRIQRYLEGSIIPEDRGSCSLMSGPPFARELHIEIVSSPHYSANGDYDHVLYRHFHTPRVVQEGDVLCVPTVGQVEILEGSPEKLPRLSASSCDLCQVRHPARNAWLTFVNIQSFVLIGTWCFLWWREVFFKVKKAVGEAPDGPASAFLADTTHTSLYMAGSALSRVPLLPSGRSTPWDSLSPPGLEALVNELCAILKPHLQPGGTLLTGTSCVLLQGPPGSGKTTAVTAACSRLGLHLLKVPCYSLCADSSGAVETKLQAAFSRARRCRPAVLLLTAIDLLGRDRDGLDEDARVVATLRHLLLDEDPVSNCPPLMVVATTSRAQDLPTDVHTAFPHELEVPVLSEEQRLSVLQALTAHLPLGQEVNLLQLARRCAGFVVGDLYALLTHTSRVACARIRASGLAGGLSEEDEGELCAAGFPLLAEDFGQALDQLQTAHSQAVGAPKIPSVSWHDVGGLQDVKKEILETIQLPLEHPELLSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGASEDRASQLRVLSAITRKFKLEASVSLVNVLDRCPPQLTGADLYSLCSDAMTTALKRRVRDLEEGLEMGSSALLLTMEDLLQAAARLQPSVSEQELLRYKRIQRKFAAC", "length": 1018, "header": "tr|A0A9J7HA39-1|A0A9J7HA39_CRIGR Isoform 1 of Peroxisomal ATPase PEX6 OS=Cricetulus griseus OX=10029 GN=Pex6 PE=3 SV=1 CANONICAL=A0A9J7HA39-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J8N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39/entry#A0A9J7J8N2-1", "sequence": { "sequence": "MALAVLRVLDPFPAETPPLAVLLPPGGPWPATGLGLVLALRPASESPAGPALLVAALEGPGSQNGQRGPGPPQLLVSRALLRLLALGPGARVRARPVRRPPALGWALLGSAPGPGPGPRVGPLLVRRGESLPVPGSRVLETRPALQGLLGPGTRLAVTELRGRAKLGPESTQHSRLPPPPVASSFAVSHAVRQLKGVLGGTGDALGVTRSCLRGLGLFQGEWVWVARVGEFPNTSQPHLAKVQLLEPRWDLSERLGPSSGQLGEPLADGLVFVPATLAFNLGCDPLEVGELRIQRYLEGSIIPEDRGSCSLMSGPPFARELHIEIVSSPHYSANGDYDHVLYRHFHTPRVVQEGDVLCVPTVGQVEILEGSPEKLPRWREVFFKVKKAVGEAPDGPASAFLADTTHTSLYMAGSALSRVPLLPSGRSTPWDSLSPPGLEALVNELCAILKPHLQPGGTLLTGTSCVLLQGPPGSGKTTAVTAACSRLGLHLLKVPCYSLCADSSGAVETKLQAAFSRARRCRPAVLLLTAIDLLGRDRDGLDEDARVVATLRHLLLDEDPVSNCPPLMVVATTSRAQDLPTDVHTAFPHELEVPVLSEEQRLSVLQALTAHLPLGQEVNLLQLARRCAGFVVGDLYALLTHTSRVACARIRASGLAGGLSEEDEGELCAAGFPLLAEDFGQALDQLQTAHSQAVGAPKIPSVSWHDVGGLQDVKKEILETIQLPLEHPELLSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGASEDRASQLRVLSAITRKFKLEASVSLVNVLDRCPPQLTGADLYSLCSDAMTTALKRRVRDLEEGLEMGSSALLLTMEDLLQAAARLQPSVSEQELLRYKRIQRKFAAC", "length": 980, "header": "tr|A0A9J7J8N2-1|A0A9J7J8N2_CRIGR Computationally mapped isoform of Peroxisomal ATPase PEX6 OS=Cricetulus griseus OX=10029 GN=Pex6 PE=3 SV=1 CANONICAL=A0A9J7HA39-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773621", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773621", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ], "pmid": "" }, { "name": "ubiquitin-modified protein reader activity", "id": "GO:0140036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140036", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ], "pmid": "" }, { "name": "protein transporter activity", "id": "GO:0140318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140318", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ], "pmid": "" }, { "name": "photoreceptor outer segment", "id": "GO:0001750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein import into peroxisome matrix", "id": "GO:0016558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016558", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ], "pmid": "" }, { "name": "protein import into peroxisome matrix, translocation", "id": "GO:0016561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016561", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ], "pmid": "" }, { "name": "protein unfolding", "id": "GO:0043335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043335", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ], "pmid": "" }, { "name": "protein targeting to peroxisome", "id": "GO:0006625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006625", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA39" } ], "pmid": 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{ "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MB35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB35" } ] } ] }, { "uniprot_ac": "A0A8C2MBY6", "gene_name": "Entpd3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8C2MBY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBY6" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8C2MBY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBY6" } ] } ] }, { "uniprot_ac": "A0A8C2MCA5", "gene_name": "Ddx41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MCA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCA5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MCA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCA5" } ] } ] }, { "uniprot_ac": "A0A8C2MCS3", "gene_name": "Ddx47", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MCS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCS3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MCS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCS3" } ] } ] }, { "uniprot_ac": "A0A8C2MFM1", "gene_name": "Vps4b", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFM1" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8C2MFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFM1" } ] } ] }, { "uniprot_ac": 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= ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MQ86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ86" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MQ86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ86" } ] } ] }, { "uniprot_ac": "A0A8C2MVH8", "gene_name": "Mcm7", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MVH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVH8" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8C2MVH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVH8" } ] } ] }, { "uniprot_ac": "A0A8C2MWE0", "gene_name": "Snrnp200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWE0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWE0" } ] } ] }, { "uniprot_ac": "A0A8C2MWH4", "gene_name": "Ddx25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MWH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MWH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ] } ] }, { "uniprot_ac": "A0A8C2MYM8", "gene_name": "Tdrd9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYM8" } ] } ] }, { "uniprot_ac": "A0A8C2N055", "gene_name": "Ythdc2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2N055", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N055" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2N055", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N055" } ] } ] }, { "uniprot_ac": "A0A8C2N184", "gene_name": "Entpd8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8C2N184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N184" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8C2N184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N184" } ] } ] }, { "uniprot_ac": "A0A8C2N236", "gene_name": "Atp13a4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8C2N236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N236" } ] } ] }, { "uniprot_ac": "A0A8C2N386", "gene_name": "Vcp", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2N386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N386" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8C2N386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N386" } ] } ] }, { "uniprot_ac": "A0A8C2QH91", "gene_name": "Ino80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8C2QH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH91" } ] } ] }, { "uniprot_ac": "A0A8C2QHV1", "gene_name": "Ddx20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] } ] }, { "uniprot_ac": "A0A8C2QLX9", "gene_name": "Ddx52", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QLX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLX9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QLX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLX9" } ] } ] }, { "uniprot_ac": "A0A8C2QM19", "gene_name": "Clpx", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QM19" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8C2QM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QM19" } ] } ] }, { "uniprot_ac": "A0A8C2QNE7", "gene_name": "Eif4a3", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNE7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNE7" } ] } ] }, { "uniprot_ac": "A0A9J7F1E5", "gene_name": "Hltf", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A9J7F1E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A9J7F1E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E5" } ] } ] }, { "uniprot_ac": "A0A9J7F876", "gene_name": "Ddx11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7F876", "database": 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"uniprot_ac": "A0A9J7FPK3", "gene_name": "Twnk", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7FPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPK3" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7FPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPK3" } ] } ] }, { "uniprot_ac": "A0A9J7FTT2", "gene_name": "Mcm5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A9J7FTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT2" } ] } ] }, { "uniprot_ac": "A0A9J7FU33", "gene_name": 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phosphate + H(+).", "evidence": [ { "id": "A0A9J7FXI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXI2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FXI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXI2" } ] } ] }, { "uniprot_ac": "A0A9J7FYM8", "gene_name": "Ddx54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYM8" } ] } ] }, { "uniprot_ac": "A0A9J7G1N4", "gene_name": "Fancm", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G1N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1N4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G1N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1N4" } ] } ] }, { "uniprot_ac": "A0A9J7G2T1", "gene_name": "Dhx9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G2T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G2T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T1" } ] } ] }, { "uniprot_ac": "A0A9J7G412", "gene_name": "Helz2", "activity": [ { "ec_number": "3.1.13.1", "activity": "Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] }, { "ec_number": "3.1.13.1", "activity": "", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] } ] }, { "uniprot_ac": "A0A9J7G5W9", "gene_name": "Spata5l1", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A9J7G5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W9" } ] } ] }, { "uniprot_ac": "A0A9J7G659", "gene_name": "Rtel1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A0A9J7G659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G659" } ] } ] }, { "uniprot_ac": "A0A9J7G6M1", "gene_name": "Mcm8", "activity": [ { "ec_number": "2.7.8.41", "activity": "a CDP-1,2-diacyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + CMP + H(+).", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M1" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M1" } ] }, { "ec_number": "2.7.8.41", "activity": "", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": 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"evidence": [ { "id": "A0A9J7G7V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G7V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8" } ] } ] }, { "uniprot_ac": "A0A9J7GCV1", "gene_name": "Ddx31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GCV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7GCV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1" } ] } ] }, { "uniprot_ac": "A0A9J7GDX9", "gene_name": "Hfm1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7GDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9" } ] } ] }, { "uniprot_ac": "A0A9J7GF88", "gene_name": "Dhx33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GF88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF88" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7GF88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF88" } ] } ] }, { "uniprot_ac": "A0A9J7GHR4", "gene_name": "Ercc2", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7GHR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHR4" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7GHR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHR4" } ] } ] }, { "uniprot_ac": "A0A9J7GID0", "gene_name": "LOC103158905", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GID0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GID0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7GID0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GID0" } ] } ] }, { "uniprot_ac": "A0A9J7GN75", "gene_name": "LOC100753355", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GN75" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7GN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GN75" } ] } ] }, { "uniprot_ac": "A0A9J7GR00", "gene_name": "Entpd1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A9J7GR00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR00" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A9J7GR00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR00" } ] } ] }, { "uniprot_ac": "A0A9J7GRQ0", "gene_name": "Ak6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A9J7GRQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRQ0" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A9J7GRQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRQ0" } ] } ] }, { "uniprot_ac": "A0A9J7H1K5", "gene_name": "LOC100755041", 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predicted by automated computational analysis. 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"https://www.ebi.ac.uk/interpro/entry/IPR043151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763050", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763050", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HAJ0", "url": "https://www.orthodb.org/?gene=A0A9J7HAJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16062", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16062", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16062:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16062:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01426", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01426", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308462", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308462", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HA71", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA71-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAR8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAV7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBI7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCW0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HD62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HD62-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HF18", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HF18-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7E9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7E9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K443", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K443-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K443-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KF55", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KF55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KF55-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KF55-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDTQGTEGSSPSYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKTIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRIRTASNLAAARLTGPSHSKSSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSTIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKQSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGTAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDNRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1708, "header": "tr|A0A9J7HAJ0-1|A0A9J7HAJ0_CRIGR Isoform 1 of Protein polybromo-1 OS=Cricetulus griseus OX=10029 GN=Pbrm1 PE=4 SV=1 CANONICAL=A0A9J7HAJ0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HA71-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0/entry#A0A9J7HA71-1", "sequence": { "sequence": "MKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDTQGTEGSSPSYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKTIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRIRTASNLAAARLTGPSHSKSSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSTIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKQSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGTAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDNRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1693, "header": "tr|A0A9J7HA71-1|A0A9J7HAJ0_CRIGR Computationally mapped isoform of Protein polybromo-1 OS=Cricetulus griseus OX=10029 GN=Pbrm1 PE=4 SV=1 CANONICAL=A0A9J7HAJ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0/entry#A0A9J7HAJ0-1", "sequence": { "sequence": "MKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDTQGTEGSSPSYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKTIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRIRTASNLAAARLTGPSHSKSSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSTIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKQSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGTAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDNRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1708, "header": "tr|A0A9J7HAJ0-1|A0A9J7HAJ0_CRIGR Isoform 1 of Protein polybromo-1 OS=Cricetulus griseus OX=10029 GN=Pbrm1 PE=4 SV=1 CANONICAL=A0A9J7HAJ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0/entry#A0A9J7HAR8-1", "sequence": { "sequence": "MKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDTQGTEGSSPSYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKTIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRIRTASNLAAARLTGPSHSKSSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSTIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKQSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKRAEKSEDSSGTAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDNRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1707, "header": "tr|A0A9J7HAR8-1|A0A9J7HAR8_CRIGR Computationally mapped isoform of Protein polybromo-1 OS=Cricetulus griseus OX=10029 GN=Pbrm1 PE=4 SV=1 CANONICAL=A0A9J7HAJ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0/entry#A0A9J7HAV7-1", "sequence": { "sequence": "MKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDTQGTEGSSPSYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKTIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRIRTASNLAAARLTGPSHSKSSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSTIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKQSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGTAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDNRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1638, "header": "tr|A0A9J7HAV7-1|A0A9J7HAV7_CRIGR Computationally mapped isoform of Protein polybromo-1 OS=Cricetulus griseus OX=10029 GN=Pbrm1 PE=4 SV=1 CANONICAL=A0A9J7HAJ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HBI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0/entry#A0A9J7HBI7-1", "sequence": { "sequence": "MKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDTQGTEGSSPSYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKTIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRIRTASNLAAARLTGPSHSKSSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSTIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKQSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGTAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDNRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1601, "header": "tr|A0A9J7HBI7-1|A0A9J7HBI7_CRIGR Computationally mapped isoform of Protein polybromo-1 OS=Cricetulus griseus OX=10029 GN=Pbrm1 PE=4 SV=1 CANONICAL=A0A9J7HAJ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HCW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0/entry#A0A9J7HCW0-1", "sequence": { "sequence": "MGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDTQGTEGSSPSYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKTIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRIRTASNLAAARLTGPSHSKSSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSTIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKQSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGTAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDNRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1580, "header": "tr|A0A9J7HCW0-1|A0A9J7HCW0_CRIGR Computationally mapped isoform of Protein polybromo-1 OS=Cricetulus griseus OX=10029 GN=Pbrm1 PE=4 SV=1 CANONICAL=A0A9J7HAJ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HD62-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0/entry#A0A9J7HD62-1", "sequence": { "sequence": "MKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDTQGTEGSSPSYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKTIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRIRTASNLAAARLTGPSHSKSSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSTIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKQSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGTAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDNRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1641, "header": "tr|A0A9J7HD62-1|A0A9J7HD62_CRIGR Computationally mapped isoform of Protein polybromo-1 OS=Cricetulus griseus OX=10029 GN=Pbrm1 PE=4 SV=1 CANONICAL=A0A9J7HAJ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HDR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0/entry#A0A9J7HDR3-1", "sequence": { "sequence": "MKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDTQGTEGSSPSYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKTIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRISNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSTIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKQSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGTAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDNRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1676, "header": "tr|A0A9J7HDR3-1|A0A9J7HDR3_CRIGR Computationally mapped isoform of Protein polybromo-1 OS=Cricetulus griseus OX=10029 GN=Pbrm1 PE=4 SV=1 CANONICAL=A0A9J7HAJ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HDW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0/entry#A0A9J7HDW9-1", "sequence": { "sequence": "MKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDTQGTEGSSPSYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKTIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRIRTASNLAAARLTGPSHSKSSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSTIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKQSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGTAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDNRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1653, "header": "tr|A0A9J7HDW9-1|A0A9J7HDW9_CRIGR Computationally mapped isoform of Protein polybromo-1 OS=Cricetulus griseus OX=10029 GN=Pbrm1 PE=4 SV=1 CANONICAL=A0A9J7HAJ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HF18-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0/entry#A0A9J7HF18-1", "sequence": { "sequence": "MKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDTQGTEGSSPSYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKTIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRISNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSTIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKQSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGTAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDNRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1606, "header": "tr|A0A9J7HF18-1|A0A9J7HF18_CRIGR Computationally mapped isoform of Protein polybromo-1 OS=Cricetulus griseus OX=10029 GN=Pbrm1 PE=4 SV=1 CANONICAL=A0A9J7HAJ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J7E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0/entry#A0A9J7J7E9-1", "sequence": { "sequence": "MGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDTQGTEGSSPSYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKTIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRIRTASNLAAARLTGPSHSKSSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSTIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKQSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGTAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDNRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1702, "header": "tr|A0A9J7J7E9-1|A0A9J7J7E9_CRIGR Computationally mapped isoform of Protein polybromo-1 OS=Cricetulus griseus OX=10029 GN=Pbrm1 PE=4 SV=1 CANONICAL=A0A9J7HAJ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K443-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0/entry#A0A9J7K443-1", "sequence": { "sequence": "MKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDTQGTEGSSPSYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKTIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRISNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSTIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKQSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGTAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDNRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1569, "header": "tr|A0A9J7K443-1|A0A9J7HAJ0_CRIGR Computationally mapped isoform of Protein polybromo-1 OS=Cricetulus griseus OX=10029 GN=Pbrm1 PE=4 SV=1 CANONICAL=A0A9J7HAJ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0/entry#A0A9J7KBZ9-1", "sequence": { "sequence": "MKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDTQGTEGSSPSYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKTIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRIRTASNLAAARLTGPSHSKSSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSTIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKQSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKRAEKSEDSSGTAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDNRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1600, "header": "tr|A0A9J7KBZ9-1|A0A9J7HAJ0_CRIGR Computationally mapped isoform of Protein polybromo-1 OS=Cricetulus griseus OX=10029 GN=Pbrm1 PE=4 SV=1 CANONICAL=A0A9J7HAJ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KF55-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0/entry#A0A9J7KF55-1", "sequence": { "sequence": "MKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVPTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKAYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDTQGTEGSSPSYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKTIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRIRTASNLAAARLTGPSHSKSSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNNQGQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSTIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKDKRKELGPLPDDDDMASPKLKQSRKSGVSPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVESNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIRIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGTAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDNRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIIPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV", "length": 1656, "header": "tr|A0A9J7KF55-1|A0A9J7HAJ0_CRIGR Computationally mapped isoform of Protein polybromo-1 OS=Cricetulus griseus OX=10029 GN=Pbrm1 PE=4 SV=1 CANONICAL=A0A9J7HAJ0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1490, "start_aa": "Thr", "end_pos": 1490, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1490", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 34, "start_aa": "Thr", "end_pos": 34, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr34", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K443" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K443" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763050", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763050", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0" } ], "pmid": "" }, { "name": "RSC-type complex", "id": "GO:0016586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016586", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1021, "end_pos": 1023, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1281, "end_pos": 1283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1401, "end_pos": 1403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 690, "end_pos": 692, "annotation": "n_glycosylation_sequon" }, { "start_pos": 792, "end_pos": 794, "annotation": "n_glycosylation_sequon" }, { "start_pos": 874, "end_pos": 876, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HAJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0" }, { "id": "PS51038", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51038" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAH", "eco_id": "ECO_0000259", "start_pos": 975, "end_pos": 1093, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7HAJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0" }, { "id": "PS50014", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromo", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 140, "start_aa": "Gln", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7HAJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ0" }, { "id": "PS50118", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMG box", "eco_id": "ECO_0000259", "start_pos": 1398, "end_pos": 1466, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 34, 1490 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1021, "end_pos": 1023 }, { "start_pos": 1281, "end_pos": 1283 }, { "start_pos": 1401, "end_pos": 1403 }, { "start_pos": 243, "end_pos": 245 }, { "start_pos": 470, "end_pos": 472 }, { "start_pos": 690, "end_pos": 692 }, { "start_pos": 792, "end_pos": 794 }, { "start_pos": 874, "end_pos": 876 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HAJ4-1", "uniprot_ac": "A0A9J7HAJ4", "uniprot_id": "A0A9J7HAJ4_CRIGR", "mass": { "chemical_mass": 86569.0, "monoisotopic_mass": 86569.0 }, "refseq": { "ac": "XP_035308477", "name": "UV-stimulated scaffold protein A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308477" }, "gene_names": [ { "name": "Uvssa", "type": "recommended", "evidence": [ { "id": "A0A9J7HAJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ4" } ] }, { "name": "Uvssa", "type": "synonym", "evidence": [ { "id": "XP_035308477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308477" } ] } ], "protein_names": [ { "name": "UV-stimulated scaffold protein A", "type": "recommended", "evidence": [ { "id": "A0A9J7HAJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ4/entry#names_and_taxonomy" } ] }, { "name": "UV-stimulated scaffold protein A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035308477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308477" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308477", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308477" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Uvssa", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ4", "locus": {} } ], "crossref": [ { "id": "100766412", "url": "https://www.ncbi.nlm.nih.gov/gene/100766412", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766412", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766412", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HAJ4", "url": "https://www.orthodb.org/?gene=A0A9J7HAJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28670", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28670", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28670:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28670:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09740", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09740", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20867", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20867", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308477", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308477", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HA80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA80-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDS4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J5X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J5X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQKLSQLIEELTTSGESQLNAQKMKELKKICKSSEEQLSHAYHLLKTQLTQDHAEIRLSAFQIVDELFTRSHQFRVLLVSDFQEFLELTLGTDNDHPLPPPREAAQRLKQAAMQAVEGWNEKFGEAYKKLALGYHFLKHTKKVDFQDVNARTVAERKREEEKQKHLDKIHRESAERAKREMEEMSDEIRCCLTEVENCFKLLVPLDLGPYPEDKFFGEATSHESDLPGSQNEEQPCCSKDLVASTYHVESVVGLKALAQSSMQDPSRDEDEHSDPEEFLRSHGLGSHKYTLDVELPSAYRSFLETLPSRHLKEMKSLSRKGRMAGVTETLEPTGEDSPERKTREGGSERSSPLDGLKVLENEDNLAVLHAARDSLRLIQIKFLPAVCSWVQRFTRAGIYSEHLKQAIDLKMELELALKKYEELNIKPERGQRSRTEALEDSEDEDQDFVEVPEKEGYEPRIPDHLRAEYGLEPKAPLKTLEKGPAVCSLQERTRMRKEEEASDPTSAAAQLLRLQDCLPSNSPSSTRVFLGPEEAQKQAEWARAPIVPFGVDLCYWGQEKLTSGKILKSDSQHRFWKPSEIEEEVDSAQVSEMLHSRHITFAGKFEPVQHQCRALRPNGKLCERQDRLKCPFHGKIIPRDDKGQPLNPEDRAREQRQQLQRQQAHPDWQDPEFMKDVEAATGVDLGSSKYSKKGKGKKKKHPNLTDLREHANTTRARLEKKIFAKAAVQRVVAAMNQMDQKKHEKFANQFNYALN", "length": 756, "header": "tr|A0A9J7HAJ4-1|A0A9J7HAJ4_CRIGR Isoform 1 of UV-stimulated scaffold protein A OS=Cricetulus griseus OX=10029 GN=Uvssa PE=3 SV=1 CANONICAL=A0A9J7HAJ4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HA80-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ4/entry#A0A9J7HA80-1", "sequence": { "sequence": "MYAFCALGLVTELCHYRKRYGSETLTVDRGAHNFRRIPTECSENEGTEENLQEFLELTLGTDNDHPLPPPREAAQRLKQAAMQAVEGWNEKFGEAYKKLALGYHFLKHTKKVDFQDVNARTVAERKREEEKQKHLDKIHRESAERAKREMEEMSDEIRCCLTEVENCFKLLVPLDLGPYPEDKFFGEATSHESDLPGSQNEEQPCCSKDLVASTYHVESVVGLKALAQSSMQDPSRDEDEHSDPEEFLRSHGLGSHKYTLDVELPSAYRSFLETLPSRHLKEMKSLSRKGRMAGVTETLEPTGEDSPERKTREGGSERSSPLDGLKVLENEDNLAVLHAARDSLRLIQIKFLPAVCSWVQRFTRAGIYSEHLKQAIDLKMELELALKKYEELNIKPERGQRSRTEALEDSEDEDQDFVEVPEKEGYEPRIPDHLRAEYGLEPKAPLKTLEKGPAVCSLQERTRMRKEEEASDPTSAAAQLLRLQDCLPSNSPSSTRVFLGPEEAQKQAEWARAPIVPFGVDLCYWGQEKLTSGKILKSDSQHRFWKPSEIEEEVDSAQVSEMLHSRHITFAGKFEPVQHQCRALRPNGKLCERQDRLKCPFHGKIIPRDDKGQPLNPEDRAREQRQQLQRQQAHPDWQDPEFMKDVEAATGVDLGSSKYSKKGKGKKKKHPNLTDLREHANTTRARLEKKIFAKAAVQRVVAAMNQMDQKKHEKFANQFNYALN", "length": 724, "header": "tr|A0A9J7HA80-1|A0A9J7HAJ4_CRIGR Computationally mapped isoform of UV-stimulated scaffold protein A OS=Cricetulus griseus OX=10029 GN=Uvssa PE=3 SV=1 CANONICAL=A0A9J7HAJ4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ4/entry#A0A9J7HAJ4-1", "sequence": { "sequence": "MDQKLSQLIEELTTSGESQLNAQKMKELKKICKSSEEQLSHAYHLLKTQLTQDHAEIRLSAFQIVDELFTRSHQFRVLLVSDFQEFLELTLGTDNDHPLPPPREAAQRLKQAAMQAVEGWNEKFGEAYKKLALGYHFLKHTKKVDFQDVNARTVAERKREEEKQKHLDKIHRESAERAKREMEEMSDEIRCCLTEVENCFKLLVPLDLGPYPEDKFFGEATSHESDLPGSQNEEQPCCSKDLVASTYHVESVVGLKALAQSSMQDPSRDEDEHSDPEEFLRSHGLGSHKYTLDVELPSAYRSFLETLPSRHLKEMKSLSRKGRMAGVTETLEPTGEDSPERKTREGGSERSSPLDGLKVLENEDNLAVLHAARDSLRLIQIKFLPAVCSWVQRFTRAGIYSEHLKQAIDLKMELELALKKYEELNIKPERGQRSRTEALEDSEDEDQDFVEVPEKEGYEPRIPDHLRAEYGLEPKAPLKTLEKGPAVCSLQERTRMRKEEEASDPTSAAAQLLRLQDCLPSNSPSSTRVFLGPEEAQKQAEWARAPIVPFGVDLCYWGQEKLTSGKILKSDSQHRFWKPSEIEEEVDSAQVSEMLHSRHITFAGKFEPVQHQCRALRPNGKLCERQDRLKCPFHGKIIPRDDKGQPLNPEDRAREQRQQLQRQQAHPDWQDPEFMKDVEAATGVDLGSSKYSKKGKGKKKKHPNLTDLREHANTTRARLEKKIFAKAAVQRVVAAMNQMDQKKHEKFANQFNYALN", "length": 756, "header": "tr|A0A9J7HAJ4-1|A0A9J7HAJ4_CRIGR Isoform 1 of UV-stimulated scaffold protein A OS=Cricetulus griseus OX=10029 GN=Uvssa PE=3 SV=1 CANONICAL=A0A9J7HAJ4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HDS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ4/entry#A0A9J7HDS4-1", "sequence": { "sequence": "MSMLGLWQKGSEKRRSRSTWIKSTEKVLNGLRGKWKNEEQPCCSKDLVASTYHVESVVGLKALAQSSMQDPSRDEDEHSDPEEFLRSHGLGSHKYTLDVELPSAYRSFLETLPSRHLKEMKSLSRKGRMAGVTETLEPTGEDSPERKTREGGSERSSPLDGLKVLENEDNLAVLHAARDSLRLIQIKFLPAVCSWVQRFTRAGIYSEHLKQAIDLKMELELALKKYEELNIKPERGQRSRTEALEDSEDEDQDFVEVPEKEGYEPRIPDHLRAEYGLEPKAPLKTLEKGPAVCSLQERTRMRKEEEASDPTSAAAQLLRLQDCLPSNSPSSTRVFLGPEEAQKQAEWARAPIVPFGVDLCYWGQEKLTSGKILKSDSQHRFWKPSEIEEEVDSAQVSEMLHSRHITFAGKFEPVQHQCRALRPNGKLCERQDRLKCPFHGKIIPRDDKGQPLNPEDRAREQRQQLQRQQAHPDWQDPEFMKDVEAATGVDLGSSKYSKKGKGKKKKHPNLTDLREHANTTRARLEKKIFAKAAVQRVVAAMNQMDQKKHEKFANQFNYALN", "length": 561, "header": "tr|A0A9J7HDS4-1|A0A9J7HDS4_CRIGR Computationally mapped isoform of UV-stimulated scaffold protein A isoform X4 OS=Cricetulus griseus OX=10029 GN=Uvssa PE=4 SV=1 CANONICAL=A0A9J7HAJ4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J5X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ4/entry#A0A9J7J5X6-1", "sequence": { "sequence": "MDQKLSQLIEELTTSGESQLNAQKMKELKKICKSSEEQLSHAYHLLKTQLTQDHAEIRLSAFQIVDELFTRSHQFRVLLVSDFQEFLELTLGTDNDHPLPPPREAAQRLKQAAMQAVEGWNEKFGEAYKKLALGYHFLKHTKKVDFQDVNARTVAERKREEEKQKHLDKIHRESAERAKREMEEMSDEIRCCLTEVENCFKLLVPLDLGPYPEDKFFGEATSHESDLPGSQNEEQPCCSKDLVASTYHVESVVGLKALAQSSMQDPSRDEDEHSDPEEFLRSHGLGSHKYTLDVELPSDGLKVLENEDNLAVLHAARDSLRLIQIKFLPAVCSWVQRFTRAGIYSEHLKQAIDLKMELELALKKYEELNIKPERGQRSRTEALEDSEDEDQDFVEVPEKEGYEPRIPDHLRAEYGLEPKAPLKTLEKGPAVCSLQERTRMRKEEEASDPTSAAAQLLRLQDCLPSNSPSSTRVFLGPEEAQKQAEWARAPIVPFGVDLCYWGQEKLTSGKILKSDSQHRFWKPSEIEEEVDSAQVSEMLHSRHITFAGKFEPVQHQCRALRPNGKLCERQDRLKCPFHGKIIPRDDKGQPLNPEDRAREQRQQLQRQQAHPDWQDPEFMKDVEAATGVDLGSSKYSKKGKGKKKKHPNLTDLREHANTTRARLEKKIFAKAAVQRVVAAMNQMDQKKHEKFANQFNYALN", "length": 700, "header": "tr|A0A9J7J5X6-1|A0A9J7J5X6_CRIGR Computationally mapped isoform of UV-stimulated scaffold protein A OS=Cricetulus griseus OX=10029 GN=Uvssa PE=3 SV=1 CANONICAL=A0A9J7HAJ4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA80" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA80" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766412", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766412", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAJ4" } ], "pmid": "" }, { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000993", "evidence": [ { "database": "UniProtKB", "id": 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"header": "tr|A0A9J7HA88-1|A0A9J7HA88_CRIGR Isoform 1 of Nonsense-mediated mRNA decay factor OS=Cricetulus griseus OX=10029 GN=LOC113837422 PE=4 SV=1 CANONICAL=A0A9J7HA88-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HA88-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA88/entry#A0A9J7HA88-1", "sequence": { "sequence": 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"header": "tr|A0A9J7HA88-1|A0A9J7HA88_CRIGR Isoform 1 of Nonsense-mediated mRNA decay factor OS=Cricetulus griseus OX=10029 GN=LOC113837422 PE=4 SV=1 CANONICAL=A0A9J7HA88-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 151, "start_aa": "Thr", "end_pos": 151, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr151", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA88", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA88" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HA98-1", "uniprot_ac": "A0A9J7HA98", "uniprot_id": "A0A9J7HA98_CRIGR", "mass": { "chemical_mass": 302730.0, "monoisotopic_mass": 302730.0 }, "refseq": { "ac": "XP_035305562", "name": "thyroglobulin isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305562" }, "gene_names": [ { "name": "LOC107977585", "type": "recommended", "evidence": [ { "id": "A0A9J7HA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA98" } ] }, { "name": "LOC107977585", "type": "synonym", "evidence": [ { "id": "XP_035305562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305562" } ] } ], "protein_names": [ { "name": "Thyroglobulin", "type": "recommended", "evidence": [ { "id": "A0A9J7HA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA98/entry#names_and_taxonomy" } ] }, { "name": "thyroglobulin isoform X3", "type": "synonym", "evidence": [ { "id": "XP_035305562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305562" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305562" } ] }, { "annotation": "Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA98", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA98#function" }, { "database": "UniProtKB", "id": "ARBA00059113", "url": "https://www.uniprot.org/uniprotkb/ARBA00059113#function" }, { "database": "UniProtKB", "id": "A0A9J7GHS9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHS9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA98", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA98" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC107977585", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA98", "locus": {} } ], "crossref": [ { "id": "cd00191", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00191", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107977585", "url": "https://www.ncbi.nlm.nih.gov/gene/107977585", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016324", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016324", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:107977585", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:107977585", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HA98", "url": "https://www.orthodb.org/?gene=A0A9J7HA98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14093", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14093", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14093:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14093:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00086", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00086", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00135", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00135", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305562", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GHS9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GHS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA98", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA98-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA98-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALVLWVFALLSSVCLAAANIFEYQVDAQPLRPCELQREKAFLKQAGYVPQCSEDGNFRTVQCQNDGRSCWCVDVDGREVPGSRQLGRPTACLSFCQLHRQQILLSSYINSTDAPYLPQCQDSGDYAPVQCGLGQVQCWCVDTEGMEVYGTRQPGRPTRCPRSCEIRNRRLLHGVGDKSPPQCSADGEFMAVQCKFVNTTDMMIFDLIHSYNRFPDAFVTFSSFRSRFPEVSGYCYCADSQGRELAETGLELLLDEIYDTIFAGLDRASTFTQSTLYRILQRRFLAIQFIISGRFRCPTKCEVESFAATRYGHPYIPRCSRNGGYQATQCQTEGPCWCVDAQGTEIPGTRQQGQSPSCAEDQSCASERQQALSRLYFGTPGYFSQQDLPSSEDRQVPESGARLATSCPPTVKELFVDSGLLRSMAGEQYQQLSASGSLLREAIRAIFPSRELAGLALRFTTNPKRLQQNLFGGTFLVNAAQFNLSGALGTRGAFNFSQFFQQLGLPGFQDGDRATDLAKLRPVGLDSNSTPETPRISEKTVAMNKPVVGTFGFEVNLQENQNALKFLASLLELPEFLVFLQRALSVPEDIARDLGDVVEIVFSAQACGQTPGRLFVPSCTAGGSYEEIQCYAGECWCVDSRGKELDGSRVRGRRPRCPTKCEKQRAQMQSLAGSQPAGSSFFVPSCTREGYFLPVQCFDSVCYCVDAEGQAIPGTQSTIGEPKQCPSVCQLQAEQAFLEAVQVLMSNVSTLPSPSSVYIPQCSASGQWRRVQCDGPPEQVFEWYERWNTQNSGGQELAPAALLMKIVSSRETASRNFSLFLQSLYEAGEQRIFPVLAQYPSLPDVPQAVLEGAPTQPGENVLLDPYVFWQALNGQLRRYPGPYTDFSKPLAHFDLRSCWCVEETGQELDGTRNKPGEIPTCPGPCEEVKLRALKFIKETEEIVLASNGSSFPLGESFLVAEGIQLTSEELGLPPLHPLREETFSEKFLRGAEYAIRLAAQSTLNFYQRLRAPQGESDEAASPLWSGPYVPQCDVLGGWEPMQCHAGTGHCWCVDGHGEFIPTSLTTRSTQRPQCPTSCELSRANGLLSAWKQAGPQGNPGPGDLFTPSCLQTGQYARQQSSPTGTWCVDPASGERTPPNTNGSAQCPGLCDVLKSGTLTRKVSPGYTPICEAQGGGFSPVQCDMAQGSCWCVLDNGEEVPGTRVEGTQPACESPQCPLPFSESDVTDGVVFCETAAGPGVTAVQQCQLLCLEGRQSAFPLGPLTCSLESRRWVSPPPLRACQRPQPWQTMKTQAHFQLLLPPGKMCSTDYSGLLLAFQVFILDELATRGFCQIWVKTFETLVSSTVCDNSSVQVGCLTAERLGVNVTWKLQLGDISVASLPDLLSIERALVGQDLLGRFADLIQSSKFQFHLDSKTFPADTSLYFLHGGSFVTSPRTQLGCLEGFYRISATSQDPLGCVKCPEGSFSQDGRCNPCPVGTYQEQAGSSTCIPCPRGRTTIATGAFSKAHCVTDCQRNEAGLQCDQDGQYQAIQRDRDSGTAFCVDSEGQRLQWLQTEAELSDSQCQTMQKFEKVPEAKVIFDASSPVIVKSKVPSAGSPLVQCLADCADDKACSFLTVSTMGPEVSCDFYSWTRDNFACMTFDQEQDAVGTGSSKAARFRSLQCQVKVRASGADSLAVYAKKGHKYTAASQKSFEPTGFQNVLSGLYSPAVFSASGTTLTDAHLFCLLACDRDSCCDGFILTQVKAGPTICGLLSSPDVLACHINDWRNDSDTQANATCAGVTYDQGTRQMALVLGGQEFLQGLTLLEGTQEAVTSFQQVYLWKDSDVGSRPESMGCGRGVVPRLDSPAEADVATELFLPLDATQVIVNTSHSLPSKQYWLFTHLFSPEQANLWCLARCAQEPTFCRLADITETSPLYFTCSLYPEAQVCDSVLESNAKNCSQVLPRQPKALFRKKVVLNERVNNFYTRLPFQKLTGISIRDKIPMSGKPISNGFFECERLCDRDPCCTGFGFLNVSQLQGGEVACLTLSSMGIHTCSEENGATWRILDCGSGDTEVSTYPFGWYQKPAVQSDIPSFCPSAALPSLTEEKVALNSWQTLPLSSAIIDPSIKHFDVAHISTTATSNFSVARDFCLQECSRHQACLVTTLQIQPGGVRCVFYPDTHNCMHSLRSQTCWLLLREEAEYIYRKSGTPRLLSGVASAPSVRIDPFGQLQGGSRVIKVGTSWKQVYQFLGVPYAAPPLGDNRFGPPELLNWTGSWDATKPRASCWQPGTPTPTPPQISEDCLYLNVFVPEDLVSNASVLVFFHNTMEMEGGGGQLTIDGSILAAVGNFIVVTANYRVGVFGFLSSGSDEVAGNWGLLDQVAALTWVQTHIGAFGGDPRRVTLASDRGGADVASLHLLITRAARIQLFRRALLMGGSALSPAAVISPDRAQRQAVALAKDVGCLGSIQEVVSCLRQKPANILNDGQTKLLAVSGPFHYWGPVVDGQYLREVPARALKRPLPAKVDLLIGGSQDDGIINRAKAVKQFEERQGRTNSKTAFYQALQNSLGGEDSDAGILAAAVWYYSLEHSTDDYASFSRALENATRDYFIICPMINMASLWARRTRGNVFMYHVPENYGHGSLELLADVQYAFGLPFYSAHQGQFSRAEQSLSLKVMQYFSNFIRSGNPNYPHEFSRKASEFAAPWPDFVPGAAGESYKEFSAQLPNRQGLKRADCSFWSKYIQALKDAGNGAKDAQLTNSGEEGRAVESGLEEDFSGSLEPGPKSYSK", "length": 2770, "header": "tr|A0A9J7HA98-1|A0A9J7HA98_CRIGR Isoform 1 of Thyroglobulin OS=Cricetulus griseus OX=10029 GN=LOC107977585 PE=3 SV=1 CANONICAL=A0A9J7HA98-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GHS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA98/entry#A0A9J7GHS9-1", "sequence": { "sequence": "MALVLWVFALLSSVCLAAANIFEYQVDAQPLRPCELQREKAFLKQAGYVPQCSEDGNFRTVQCQNDGRSCWCVDVDGREVPGSRQLGRPTACLSFCQLHRQQILLSSYINSTDAPYLPQCQDSGDYAPVQCGLGQVQCWCVDTEGMEVYGTRQPGRPTRCPRSCEIRNRRLLHGVGDKSPPQCSADGEFMAVQCKFVNTTDMMIFDLIHSYNRFPDAFVTFSSFRSRFPEVSGYCYCADSQGRELAETGLELLLDEIYDTIFAGLDRASTFTQSTLYRILQRRFLAIQFIISGRFRCPTKCEVESFAATRYGHPYIPRCSRNGGYQATQCQTEGPCWCVDAQGTEIPGTRQQGQSPSCAEDQSCASERQQALSRLYFGTPGYFSQQDLPSSEDRQVPESGARLATSCPPTVKELFVDSGLLRSMAGEQYQQLSASGSLLREAIRAIFPSRELAGLALRFTTNPKRLQQNLFGGTFLVNAAQFNLSGALGTRGAFNFSQFFQQLGLPGFQDGDRATDLAKLRPVGLDSNSTPETPRISEKTVAMNKPVVGTFGFEVNLQENQNALKFLASLLELPEFLVFLQRALSVPEDIARDLGDVVEIVFSAQACGQTPGRLFVPSCTAGGSYEEIQCYAGECWCVDSRGKELDGSRVRGRRPRCPTKCEKQRAQMQSLAGSQPAGSSFFVPSCTREGYFLPVQCFDSVCYCVDAEGQAIPGTQSTIGEPKQCPSVCQLQAEQAFLEAVQVLMSNVSTLPSPSSVYIPQCSASGQWRRVQCDGPPEQVFEWYERWNTQNSGGQELAPAALLMKIVSSRETASRNFSLFLQSLYEAGEQRIFPVLAQYPSLPDVPQAVLEGAPTQPGENVLLDPYVFWQALNGQLRRYPGPYTDFSKPLAHFDLRSCWCVEETGQELDGTRNKPGEIPTCPGPCEEVKLRALKFIKETEEIVLASNGSSFPLGESFLVAEGIQLTSEELGLPPLHPLREETFSEKFLRGAEYAIRLAAQSTLNFYQRLRAPQGESDEAASPLWSGPYVPQCDVLGGWEPMQCHAGTGHCWCVDGHGEFIPTSLTTRSTQRPQCPTSCELSRANGLLSAWKQAGPQGNPGPGDLFTPSCLQTGQYARQQSSPTGTWCVDPASGERTPPNTNGSAQCPGLCDVLKSGTLTRKVSPGYTPICEAQGGGFSPVQCDMAQGSCWCVLDNGEEVPGTRVEGTQPACESPQCPLPFSESDVTDGVVFCETAAGPGVTAVQQCQLLCLEGRQSAFPLGPLTCSLESRRWVSPPPLRACQRPQPWQTMKTQAHFQLLLPPGKMCSTDYSGLLLAFQVFILDELATRGFCQIWVKTFETLVSSTVCDNSSVQVGCLTAERLGVNVTWKLQLGDISVASLPDLLSIERALVGQDLLGRFADLIQSSKFQFHLDSKTFPADTSLYFLHGGSFVTSPRTQLGCLEGFYRISATSQDPLGCVKCPEGSFSQDGRCNPCPVGTYQEQAGSSTCIPCPRGRTTIATGAFSKAHCVTDCQRNEAGLQCDQDGQYQAIQRDRDSGTAFCVDSEGQRLQWLQTEAELSDSQCQTMQKFEKVPEAKVIFDASSPVIVKSKVPSAGSPLVQCLADCADDKACSFLTVSTMGPEVSCDFYSWTRDNFACMTFDQEQDAVGTGSSKAARFRSLQCQVKVRASGADSLAVYAKKGHKYTAASQKSFEPTGFQNVLSGLYSPAVFSASGTTLTDAHLFCLLACDRDSCCDGFILTQVKAGPTICGLLSSPDVLACHINDWRNDSDTQANATCAGVTYDQGTRQMALVLGGQEFLQGLTLLEGTQEAVTSFQQVYLWKDSDVGSRPESMGCGRGVVPRLDSPAEADVATELFLPLDATQVIVNTSHSLPSKQYWLFTHLFSPEQANLWCLARCAQEPTFCRLADITETSPLYFTCSLYPEAQVCDSVLESNAKNCSQVLPRQPKALFRKKVVLNERVNNFYTRLPFQKLTGISIRDKIPMSGKPISNGFFECERLCDRDPCCTGFGFLNVSQLQGGEVACLTLSSMGIHTCSEENGATWRILDCGSGDTEVSTYPFGWYQKPAVQSDIPSFCPSAALPSLTEEKVALNSWQTLPLSSAIIDPSIKHFDVAHISTTATSNFSVARDFCLQECSRHQACLVTTLQIQPGGVRCVFYPDTHNCMHSLRSQTCWLLLREEAEYIYRKSGTPRLLSGVASAPSVRIDPFGQLQGGSRVIKVGTSWKQVYQFLGVPYAAPPLGDNRFGPPELLNWTGSWDATKPRASCWQPGTPTPTPPQISEDCLYLNVFVPEDLVSNASVLVFFHNTMEMEGGGGQLTIDGSILAAVGNFIVVTANYRVGVFGFLSSGSDEVAGNWGLLDQVAALTWVQTHIGAFGGDPRRVTLASDRGGADVASLHLLITRAARIQLFRRALLMGGSALSPAAVISPDRAQRQAVALAKDVGCLGSIQEVVSCLRQKPANILNDGQTKLLAVSGPFHYWGPVVDGQYLREVPARALKRPLPAKVDLLIGGSQDDGIINRAKAVKQFEERQGRTNSKTAFYQALQNSLGGEDSDAGILAAAVWYYSLEHSTDDYASFSRALENATRDYFIICPMINMASLWARRTRGNVFMYHVPENYGHGSLELLADVQYAFGLPFYSAHQGQFSRAEQSLSLKVMQYFSNFIRSGNPNYPHEFSRKASEFAAPWPDFVPGAAGESYKEFSAQLPNRQGLKRADCSFWSKYIQALKDADGAKDAQLTNSGEEGRAVESGLEEDFSGSLEPGPKSYSK", "length": 2769, "header": "tr|A0A9J7GHS9-1|A0A9J7GHS9_CRIGR Computationally mapped isoform of Thyroglobulin OS=Cricetulus griseus OX=10029 GN=LOC107977585 PE=3 SV=1 CANONICAL=A0A9J7HA98-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HA98-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA98/entry#A0A9J7HA98-1", "sequence": { "sequence": "MALVLWVFALLSSVCLAAANIFEYQVDAQPLRPCELQREKAFLKQAGYVPQCSEDGNFRTVQCQNDGRSCWCVDVDGREVPGSRQLGRPTACLSFCQLHRQQILLSSYINSTDAPYLPQCQDSGDYAPVQCGLGQVQCWCVDTEGMEVYGTRQPGRPTRCPRSCEIRNRRLLHGVGDKSPPQCSADGEFMAVQCKFVNTTDMMIFDLIHSYNRFPDAFVTFSSFRSRFPEVSGYCYCADSQGRELAETGLELLLDEIYDTIFAGLDRASTFTQSTLYRILQRRFLAIQFIISGRFRCPTKCEVESFAATRYGHPYIPRCSRNGGYQATQCQTEGPCWCVDAQGTEIPGTRQQGQSPSCAEDQSCASERQQALSRLYFGTPGYFSQQDLPSSEDRQVPESGARLATSCPPTVKELFVDSGLLRSMAGEQYQQLSASGSLLREAIRAIFPSRELAGLALRFTTNPKRLQQNLFGGTFLVNAAQFNLSGALGTRGAFNFSQFFQQLGLPGFQDGDRATDLAKLRPVGLDSNSTPETPRISEKTVAMNKPVVGTFGFEVNLQENQNALKFLASLLELPEFLVFLQRALSVPEDIARDLGDVVEIVFSAQACGQTPGRLFVPSCTAGGSYEEIQCYAGECWCVDSRGKELDGSRVRGRRPRCPTKCEKQRAQMQSLAGSQPAGSSFFVPSCTREGYFLPVQCFDSVCYCVDAEGQAIPGTQSTIGEPKQCPSVCQLQAEQAFLEAVQVLMSNVSTLPSPSSVYIPQCSASGQWRRVQCDGPPEQVFEWYERWNTQNSGGQELAPAALLMKIVSSRETASRNFSLFLQSLYEAGEQRIFPVLAQYPSLPDVPQAVLEGAPTQPGENVLLDPYVFWQALNGQLRRYPGPYTDFSKPLAHFDLRSCWCVEETGQELDGTRNKPGEIPTCPGPCEEVKLRALKFIKETEEIVLASNGSSFPLGESFLVAEGIQLTSEELGLPPLHPLREETFSEKFLRGAEYAIRLAAQSTLNFYQRLRAPQGESDEAASPLWSGPYVPQCDVLGGWEPMQCHAGTGHCWCVDGHGEFIPTSLTTRSTQRPQCPTSCELSRANGLLSAWKQAGPQGNPGPGDLFTPSCLQTGQYARQQSSPTGTWCVDPASGERTPPNTNGSAQCPGLCDVLKSGTLTRKVSPGYTPICEAQGGGFSPVQCDMAQGSCWCVLDNGEEVPGTRVEGTQPACESPQCPLPFSESDVTDGVVFCETAAGPGVTAVQQCQLLCLEGRQSAFPLGPLTCSLESRRWVSPPPLRACQRPQPWQTMKTQAHFQLLLPPGKMCSTDYSGLLLAFQVFILDELATRGFCQIWVKTFETLVSSTVCDNSSVQVGCLTAERLGVNVTWKLQLGDISVASLPDLLSIERALVGQDLLGRFADLIQSSKFQFHLDSKTFPADTSLYFLHGGSFVTSPRTQLGCLEGFYRISATSQDPLGCVKCPEGSFSQDGRCNPCPVGTYQEQAGSSTCIPCPRGRTTIATGAFSKAHCVTDCQRNEAGLQCDQDGQYQAIQRDRDSGTAFCVDSEGQRLQWLQTEAELSDSQCQTMQKFEKVPEAKVIFDASSPVIVKSKVPSAGSPLVQCLADCADDKACSFLTVSTMGPEVSCDFYSWTRDNFACMTFDQEQDAVGTGSSKAARFRSLQCQVKVRASGADSLAVYAKKGHKYTAASQKSFEPTGFQNVLSGLYSPAVFSASGTTLTDAHLFCLLACDRDSCCDGFILTQVKAGPTICGLLSSPDVLACHINDWRNDSDTQANATCAGVTYDQGTRQMALVLGGQEFLQGLTLLEGTQEAVTSFQQVYLWKDSDVGSRPESMGCGRGVVPRLDSPAEADVATELFLPLDATQVIVNTSHSLPSKQYWLFTHLFSPEQANLWCLARCAQEPTFCRLADITETSPLYFTCSLYPEAQVCDSVLESNAKNCSQVLPRQPKALFRKKVVLNERVNNFYTRLPFQKLTGISIRDKIPMSGKPISNGFFECERLCDRDPCCTGFGFLNVSQLQGGEVACLTLSSMGIHTCSEENGATWRILDCGSGDTEVSTYPFGWYQKPAVQSDIPSFCPSAALPSLTEEKVALNSWQTLPLSSAIIDPSIKHFDVAHISTTATSNFSVARDFCLQECSRHQACLVTTLQIQPGGVRCVFYPDTHNCMHSLRSQTCWLLLREEAEYIYRKSGTPRLLSGVASAPSVRIDPFGQLQGGSRVIKVGTSWKQVYQFLGVPYAAPPLGDNRFGPPELLNWTGSWDATKPRASCWQPGTPTPTPPQISEDCLYLNVFVPEDLVSNASVLVFFHNTMEMEGGGGQLTIDGSILAAVGNFIVVTANYRVGVFGFLSSGSDEVAGNWGLLDQVAALTWVQTHIGAFGGDPRRVTLASDRGGADVASLHLLITRAARIQLFRRALLMGGSALSPAAVISPDRAQRQAVALAKDVGCLGSIQEVVSCLRQKPANILNDGQTKLLAVSGPFHYWGPVVDGQYLREVPARALKRPLPAKVDLLIGGSQDDGIINRAKAVKQFEERQGRTNSKTAFYQALQNSLGGEDSDAGILAAAVWYYSLEHSTDDYASFSRALENATRDYFIICPMINMASLWARRTRGNVFMYHVPENYGHGSLELLADVQYAFGLPFYSAHQGQFSRAEQSLSLKVMQYFSNFIRSGNPNYPHEFSRKASEFAAPWPDFVPGAAGESYKEFSAQLPNRQGLKRADCSFWSKYIQALKDAGNGAKDAQLTNSGEEGRAVESGLEEDFSGSLEPGPKSYSK", "length": 2770, "header": "tr|A0A9J7HA98-1|A0A9J7HA98_CRIGR Isoform 1 of Thyroglobulin OS=Cricetulus griseus OX=10029 GN=LOC107977585 PE=3 SV=1 CANONICAL=A0A9J7HA98-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2274, "start_aa": "Thr", "end_pos": 2274, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2274", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2276, "start_aa": "Thr", "end_pos": 2276, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2276", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA98", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA98" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"https://www.ncbi.nlm.nih.gov/protein/XP_035308330" }, "gene_names": [ { "name": "Lyg1", "type": "recommended", "evidence": [ { "id": "A0A9J7HA99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA99" } ] }, { "name": "Lyg1", "type": "synonym", "evidence": [ { "id": "XP_035308330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308330" } ] } ], "protein_names": [ { "name": "Lysozyme g-like protein", "type": "recommended", "evidence": [ { "id": "A0A9J7HA99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA99/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.-", "type": "synonym", "evidence": [ { "id": "A0A9J7HA99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA99/entry#names_and_taxonomy" } ] }, { "name": "lysozyme g-like protein 1", "type": "synonym", "evidence": [ { "id": "XP_035308330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308330" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308330" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA99" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lyg1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA99", "locus": {} } ], "crossref": [ { "id": "A0A9J7HA99", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HA99", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16888", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16888", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762750", "url": "https://www.ncbi.nlm.nih.gov/gene/100762750", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762750", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762750", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SHAPTSW", "url": "https://omabrowser.org/oma/group/SHAPTSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7HA99", "url": "https://www.orthodb.org/?gene=A0A9J7HA99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31698", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31698", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31698:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31698:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_035308330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308330", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HA99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA99-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPLWLLLGLLALTGSSESSNWGCYGNIRTLNTPGASCVIGRRHGLPYCGVRASERLAEIDRPYLLRYQPTMRIVGRKYCMDPAVIAGVLSRESQGGNFVVDMDNVGNGIGVIQDPNFYPPTSWKSESWVSQKTEILTSKIKEIQTRFPTWTPDQYLRGGLCAYSKGPSFVRSNQDLNCDFCNDVLARAKYFKNHGF", "length": 197, "header": "tr|A0A9J7HA99-1|A0A9J7HA99_CRIGR Isoform 1 of Lysozyme g-like protein OS=Cricetulus griseus OX=10029 GN=Lyg1 PE=3 SV=1 CANONICAL=A0A9J7HA99-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HA99-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA99/entry#A0A9J7HA99-1", "sequence": { "sequence": "MSPLWLLLGLLALTGSSESSNWGCYGNIRTLNTPGASCVIGRRHGLPYCGVRASERLAEIDRPYLLRYQPTMRIVGRKYCMDPAVIAGVLSRESQGGNFVVDMDNVGNGIGVIQDPNFYPPTSWKSESWVSQKTEILTSKIKEIQTRFPTWTPDQYLRGGLCAYSKGPSFVRSNQDLNCDFCNDVLARAKYFKNHGF", "length": 197, "header": "tr|A0A9J7HA99-1|A0A9J7HA99_CRIGR Isoform 1 of Lysozyme g-like protein OS=Cricetulus griseus OX=10029 GN=Lyg1 PE=3 SV=1 CANONICAL=A0A9J7HA99-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA99" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA99" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762750", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762750", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZZJ5-1", "protein_name": "Lysozyme g-like protein", "gene_name": "Lyg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPLWLLLGLLALTGSSESSNWGCYGNIRTLDTPGASCRIGRRYGLSYCGVRASERLAEVDRPYLLRYQPTMRLVGQKYCMDPAVIAGVLSRESPGGNFVLDMGNMGSGLGMVKESKFYPPTAWKSETWVSQKTQTLTSSIKEIKTRFPTWTTDQHLRGGLCAYSKGPNFVRSNQDLNCDFCNDVLARAKYFKNHGF", "length": 197 }, "evidence": [ { "id": "A0A9J7HA99", "url": "https://omabrowser.org/oma/group/A0A9J7HA99/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N1E2-1", "protein_name": "Lysozyme g-like protein 1", "gene_name": "LYG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSALWLLLGLLALMDLSESSNWGCYGNIQSLDTPGASCGIGRRHGLNYCGVRASERLAEIDMPYLLKYQPMMQTIGQKYCMDPAVIAGVLSRKSPGDKILVNMGDRTSMVQDPGSQAPTSWISESQVSQTTEVLTTRIKEIQRRFPTWTPDQYLRGGLCAYSGGAGYVRSSQDLSCDFCNDVLARAKYLKRHGF", "length": 194 }, "evidence": [ { "id": "A0A9J7HA99", "url": "https://omabrowser.org/oma/group/A0A9J7HA99/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D7Q0-1", "protein_name": "Lysozyme g-like protein 1", "gene_name": "Lyg1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPLWLLLGLLALTGSSESSSWGCYGNIRTLDTPGASCRIGRRYGLTYCGVRASERLAEVDRPYLLRHQPTMRLVGQKYCMDPAVIAGVLSRESPGGNYVVDLGNIGSGLGMVKETKFYPPTAWKSETWVSQKTQTLTSSIKEIKTRFPTWTADQHLRGGLCAYSKGPNFVRSNQDLNCDFCNDVLARAKYFKDHGF", "length": 197 }, "evidence": [ { "id": "A0A9J7HA99", "url": "https://omabrowser.org/oma/group/A0A9J7HA99/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA99" } ], "pmid": "" }, { "name": "peptidoglycan catabolic process", "id": "GO:0009253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009253", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA99" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lysozyme activity", "id": "GO:0003796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003796", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HAB6-1", "uniprot_ac": "A0A9J7HAB6", "uniprot_id": "A0A9J7HAB6_CRIGR", "mass": { "chemical_mass": 48260.0, "monoisotopic_mass": 48260.0 }, "refseq": { "ac": "XP_035305581", "name": "DEP domain-containing mTOR-interacting protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305581" }, "gene_names": [ { "name": "Deptor", "type": "recommended", "evidence": [ { "id": "A0A9J7HAB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB6" } ] }, { "name": "Deptor", "type": "synonym", "evidence": [ { "id": "XP_035305581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305581" } ] } ], "protein_names": [ { "name": "DEP domain-containing mTOR-interacting protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305581" }, { "id": "A0A9J7HAB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305581", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305581" } ] }, { "annotation": "Negative regulator of the mTORC1 and mTORC2 complexes: inhibits the protein kinase activity of MTOR, thereby inactivating both complexes. DEPTOR inhibits mTORC1 and mTORC2 to induce autophagy. In contrast to AKT1S1/PRAS40, only partially inhibits mTORC1 activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GNN9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNN9#function" }, { "database": "UniProtKB", "id": "ARBA00054257", "url": "https://www.uniprot.org/uniprotkb/ARBA00054257#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAB6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Deptor", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB6", "locus": {} } ], "crossref": [ { "id": "A0A9J7HAB6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HAB6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04441", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04441", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04442", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04442", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23067", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23067", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "103160978", "url": "https://www.ncbi.nlm.nih.gov/gene/103160978", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037335", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037335", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103160978", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103160978", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HAB6", "url": "https://www.orthodb.org/?gene=A0A9J7HAB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22829:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22829:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00610", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00610", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305581", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305581", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GNN9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GNN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAB6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEGSGGGGSDSNAGGSGGAQQRELERMAEVLVTGEQLRLRLHEEKVIKDRRHHLKTYPNCFVAKELIDWLIEHKEASDRETAIKLMQKLADRGIIHHVCDEHKEFKDVKLFYRFRKDDGTFPLDNEVKAFMRGQRLYEKLMSPETTLLQPREEEGVKYERTFMASEFLDWLVQEGEATTRKEGEQLCHRLMEHGIIQHVSNKHPFVDSNLLYQFRMNFRRRRRLMELLSEKSPSSQETHDSPFCLRKQSHDNRKSTSFMSVSPSKEIKIVSAVRRSSMSSCGSSGYFSSSPTLSSSPPVLCNPKSVLKRPVTSEELLTPGAPYARKTFTIVGDAVGWGFVVRGSKPCHIQAVDPSGPAAAAGMKKQEGRHDIASSTLQKPSCHLEKTVSKSYSLGLPSHDRQPWMLHGIFLSHQERAVSCPISQAH", "length": 427, "header": "tr|A0A9J7HAB6-1|A0A9J7HAB6_CRIGR Isoform 1 of DEP domain-containing mTOR-interacting protein isoform X2 OS=Cricetulus griseus OX=10029 GN=Deptor PE=4 SV=1 CANONICAL=A0A9J7HAB6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GNN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB6/entry#A0A9J7GNN9-1", "sequence": { "sequence": "MEEGSGGGGSDSNAGGSGGAQQRELERMAEVLVTGEQLRLRLHEEKVIKDRRHHLKTYPNCFVAKELIDWLIEHKEASDRETAIKLMQKLADRGIIHHVCDEHKEFKDVKLFYRFRKDDGTFPLDNEVKAFMRGQRLYEKLMSPETTLLQPREEEGVKYERTFMASEFLDWLVQEGEATTRKEGEQLCHRLMEHGIIQHVSNKHPFVDSNLLYQFRMNFRRRRRLMELLSEKSPSSQETHDSPFCLRKQSHDNRKSTSFMSVSPSKEIKIVSAVRRSSMSSCGSSGYFSSSPTLSSSPPVLCNPKSVLKRPVTSEELLTPGAPYARKTFTIVGDAVGWGFVVRGSKPCHIQAVDPSGPAAAAGMKVCQFVVSVNGLNVLNVDYRTVSNLILTGPRTIVMEVMEELDC", "length": 407, "header": "tr|A0A9J7GNN9-1|A0A9J7GNN9_CRIGR Computationally mapped isoform of DEP domain-containing mTOR-interacting protein OS=Cricetulus griseus OX=10029 GN=Deptor PE=4 SV=1 CANONICAL=A0A9J7HAB6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB6/entry#A0A9J7HAB6-1", "sequence": { "sequence": "MEEGSGGGGSDSNAGGSGGAQQRELERMAEVLVTGEQLRLRLHEEKVIKDRRHHLKTYPNCFVAKELIDWLIEHKEASDRETAIKLMQKLADRGIIHHVCDEHKEFKDVKLFYRFRKDDGTFPLDNEVKAFMRGQRLYEKLMSPETTLLQPREEEGVKYERTFMASEFLDWLVQEGEATTRKEGEQLCHRLMEHGIIQHVSNKHPFVDSNLLYQFRMNFRRRRRLMELLSEKSPSSQETHDSPFCLRKQSHDNRKSTSFMSVSPSKEIKIVSAVRRSSMSSCGSSGYFSSSPTLSSSPPVLCNPKSVLKRPVTSEELLTPGAPYARKTFTIVGDAVGWGFVVRGSKPCHIQAVDPSGPAAAAGMKKQEGRHDIASSTLQKPSCHLEKTVSKSYSLGLPSHDRQPWMLHGIFLSHQERAVSCPISQAH", "length": 427, "header": "tr|A0A9J7HAB6-1|A0A9J7HAB6_CRIGR Isoform 1 of DEP domain-containing mTOR-interacting protein isoform X2 OS=Cricetulus griseus OX=10029 GN=Deptor PE=4 SV=1 CANONICAL=A0A9J7HAB6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAB6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103160978", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103160978", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAB6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB6" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAB6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB6" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAB6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAB6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB6" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAB6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor signaling 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"A0A9J7HAB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB6" }, { "id": "PS50186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DEP", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 117, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306826" } ] }, { "annotation": "Involved in the presentation of foreign antigens to the immune system.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAB8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB8#function" }, { "database": "UniProtKB", "id": "ARBA00002297", "url": "https://www.uniprot.org/uniprotkb/ARBA00002297#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAB8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100762763", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB8", "locus": {} } ], "crossref": [ { "id": "A0A9J7HAB8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HAB8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07698", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07698", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762763", "url": "https://www.ncbi.nlm.nih.gov/gene/100762763", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011161", "url": 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"Enzyme and Pathway" ] }, { "id": "A0A9J7HAB8", "url": "https://www.orthodb.org/?gene=A0A9J7HAB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16675:SF251", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16675:SF251", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306826", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HAB8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRWRRALLLLLAAALAPSQTRAGSHSLRYFSTFVSRPGLGEPRYMEVGYVDDTQFVRFDSDAENPRMEPRAPWMEREGPEYWERETWRAKDWEQDFRLYLRTALGYYNQSEGGSHTYQVCVCGCDMGSDGRLLHGYEKHAYEGRDYLVLNEDLRTWTVADPAVQITQHMLQQDGYEERYRAYLEDECLKSLRRYLENGKDQLLRTDPPKAHVTHHPGPKGDVTLRCWAMGFYPAEITLTWQREEEEQTQDMELVETRPSGDGTFQKWAAVVVPSGEEQKYTCHVYPEGLPEPLTLRWEPPPQSTVPIMAVIAVLVLLVTIITAVVAVSRKKRRNTGVQDEDSKTHKNELILMLAAGDSGL", "length": 361, "header": "tr|A0A9J7HAB8-1|A0A9J7HAB8_CRIGR Isoform 1 of LOW QUALITY PROTEIN: H-2 class I histocompatibility antigen, Q10 alpha chain-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100762763 PE=3 SV=1 CANONICAL=A0A9J7HAB8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HAB8-1", "url": 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"Enzyme and Pathway" ] }, { "id": "A0A9J7HAQ6", "url": "https://www.orthodb.org/?gene=A0A9J7HAQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14113:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14113:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05715", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05715", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306616", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HAQ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNEASLEGEGLPEGLAAAAGGAGGSGSALHPGIPGGMEADLSQLSEEERRQIAAVMSRAQGLPEGSVPAAAAESPSMHRKQELESSQPPKQPGKPPDPGRPTQPGLSKSRTTDTFRAEQKLPGRSPSTISLKESKSRSDFKEEYKSSMMPGFLSDVNPLSAVSSVVNKFNPFDLISDSEASQEETTQKQKVAQKDQGKSEGITKPPLQQPSPKSVPKQGPAKEVIQQENALKSASSQQTEKIKPQLPSTGKPSQASSQLPPMDQAKLPIQRDTTRPQTKPSDLGKPSQQSPAKTPAQQASPGKSVAQQPGPAKASVQQPGSTKSPAPPAGTMKPPAQPPVTSKPPAQQVGVEKTLSQQPGPKSLAQTPGVGKIPPGPVKSPAQQPGTAKPPAQQPVLQPLVKVPGPAKTPAQQSGPGKTPAQQPGTAKPSPQQPLPAKPQPQQPLPAKPQPQQPLPAKPQPQQPLPAKPQPQKPLPAKPQPQQPTPAKPQPQQPTPAKPQPQQPTPAKPSAQQPVPPKPSAQQPVPPKPSAQQPMKPTSQTVTERPLQPPPPSAAQTPGQDISKTICPLCNTTELLLHIPDKANFNTCTECQTTVCSLCGFNPNPHLTEIKEWLCLNCQMQRALGGELAPIPSSPHPSPKAASVPPAVAASKPPVPSQPASPKKEPPPKQESPKAPELKKPPPLVKQPTLHGPATVTAPKPSVAEALPAASLPEQDKAPVPDVKPKQPKMAEQRADVQSSVAAATKSDVLSSQVQPQAQEQATPPLKTDSAKPSQSFPPTGEKITPFDSKALPRPSSDSKIISHPGPSSESKDLKHIDPTHKKEEPKKTQTKMSPKPDAKPVPKGSPTPSGPRPTTGQAVSPSQQSLKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPPPQTGPVVPTKPVPTPSQTPAAHGPPKSTGQFPPAPAKAMPVKKETKAPAAESSESKPEPALAVKKIEKDKKPPPGKVSKPPPAESESALLTHKPDKITKVEANCPLCKTELNIGSQEPPNFNTCTECKSQVCNLCGFNPTPHLTEIQEWLCLNCQTNRAISGQLGDMGKMPPVSSGSKASPVPAPADPSSQKTGSHMKGKKKETEVKTEAKKLIPEKETVSIEKTPPTVTTDEKLEETKLEKSKVSALQEKKSSSEEEKPRSEEKMGKEPSAEEKLASAEENPPLEGKKPTPEDKKLPPEVKPLALEGEEKHEILQAQVQIPEEKPTGSVVTKALQEEGQPEARTGDQPGHTPQPLPKQGEKESQAKQPQVEGSAKSDQVDPNKEKTEKEEDKSDTPSSQQPKSPQGLSDTGYSSDGISGSLGEIPSLIPSDEKDLLKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLSEKSEMKAQPQKVSPEQPRDAQKSQIPSDTQDITISEEEDKESQEKKESSKRDSQQGFPSRKDHKEKPELADDLSPRRASYDSVEDSSESENSPVAHRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRSQLKEIGGVTESHKREETKGKGKSAAGKHRRLTRKSSTSFDDDAGRRHSWHDEDDETYDESPELKFRETKSQESEELVVAGGGGLRRFKTIELNSAIADKYSAESSQKKTALYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKQESKQQRKARHRTHGPLLPTIEDSSEEEELREEEELLKEQEKQRELEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSVMQKEGVQKALKSAEEMYEEMMQKTHKYKAFPSANERDDVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEQNGFMQQRGREQKIRIPEQIYDDPMQKITDLQKEFYELESLHSVVPQEDIVSSSYIIPESHEIVDLGTMVTSTSEEKKLLDADTAYEELMRRQQMQVTDGSSPTQTTVGDDMAESAMDFDRVQDTSLTSSILSGASLTDSTSSATLSIPDVKITQHFSAEDLEDEYVTDYTREIQEMIAHESLILTYSEPSESAASVPPSDTPSLTSSISSVCTTDSSSPVTTLDSLTTAYTEPADVITKFEDSEEISSSTYFPGSIIDYPEDISVSLDRTTTPESRTNVDHIVISFSSIAPSVTESVGAKADRSQAVPMSTDSPICDKDPLKGKKETGDGIILEVLDAYTDKREESEAELTKISLPETGLVQTPSSFIAPQMKEQPVTPYSVSGKMSGQEKPTYRLPSASVPVSTHPSKSRPFFRSSSLDISAQPPPPPPPRPPPPFPPPPPPPLPPATSPKPTIYPKKKLAVAAPVTPTTVVTTHIDTITTVEATTARKSNGLPATKICATTPPPVPPKPSSIPTGLVFTHRPEPSKPPIAPKPAVPQIPVTTQKTTDTCPKPTALSLTSNMSLNLVTSADYKLPSPTSPLSPHSNKSSPRYSKSLMETYVVITLPSEPGTPTDSSAAQAITSWPLGSPPKDLVSLETVFSVVPAMTATEIPSSSQPTLYAPGTLETFSAAPVVTASLFQGAPTSPTKLLTTEASKTMVSTTRSAVPSIAPRSVSIPIPPEPLALDRHQYKENGNLQLIGDAIDLRTIPKTEAKATEKCMDLSASAMDVKRQTTANEVYGRQISAVQPSIMNLSAASSLVAPVTLDSETVAVVTGTAGTGSQVSVEHAMVSPLQLTTSKHTESPYRISSGQPFPMIRDEAPINLSLGPSAQPVTLAVTKPVTVPPVGVTNGWTDSTASQGIPDGEVVDLSTSKSHRTVVTMDESTSNVVTKIIEDDEKPVDLTAGRRAVCCDMVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNLAEAGHFFYKSKNAFDYSGGADAAVDLTSGRVTTGEVMDYSSKTTGPYPETRQVISGVGISTPQYSTARMTPPPGPQYGVGSVLRSSNGVVYSSVATPIPSTFAITTQPGSIFSTTVRDLSGIHTTDALTSLSALHQSQPMPRSYFITTGASETDISVTSMDINASLQTMTLETLPAETMDSVPALTTASEVFSEVVGEENTLLVVSEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQSMKQHLLYQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKLRQIYQYNYDPSGTASPQTTTEQAILEGPYAAQEGSQFWATEDATTTASTVVAIEIPQTQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKVRGQYEEMGESMADDPRNLKKIVDSGVQTDDEETADRSYASRRRKSKKSVDTSVQTDDEDQDEWDVPSRSRRKARPGKYGDSATEGDKPLSKVSSVAVQTVAEISVQTEPLGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTETDSDTQSPPYLGATSPPKDKKRPTPLEIGYSSSHLRADTTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPGSPKTAKMMQRSMSDPKPLSPTADESSRAPFQYSEGFTTKGSQTMTASGTQKKVKRTLPNPPPEEASTGTQSTYSTLGTASRRRMCRTNTMARAKILQDIDRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSSTRPSRIESQHGIERPRTAPQTEFSQFIPPQTQTEAQLVPPTSPYTQYQYSSPALPTQAPTPYTQQSHFQQQTLYHQQVSPYQTQPTFQAVATMSFTPQAQPTPSPQPSYQLPSQMMVIQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTYAVSHLGSKYNSLDLRIGLEERSSMVSSPISSISADSFYADIDHHTSRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRLLRTTETRRSQEVTDFLAPLQTSSRLHSYVKAEEDPMEDPYELKLLKQQIKQEFRRGTESLDHLAGLPHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPKMSKFSPIQESRDLEPDYPSYMSSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSLGSGLGTLGNTIRSALQDEADKSYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQEAEALDVSFGHSSSSSRTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEVAVAMYDVSLVSKAYHLRREETDWFDKPRESRLENGHVLDRKLPERLVHSRPLSQHQEQILQMNGKTMHYIFPHTRIKITRDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEHTGKLVEGMQVLEWNGIPLTSKTYEEVQSIINQQSGEAEICVRLDLNMLSDSENPQHLELHEPPKAVDKAKSPGVDPKQLAAELQKVSLQQSPLVMSSVVEKGSHAHSGPTSAGSSSVPSPGQPGSPSVSKKKHGSSKPTDATKVASHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGAEYKRRTKYVQKSLNPEWNQTVIYKSISMEQLMKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAAEAAVQQLRIQPTKPANHRPAESSVSTGSSGSSVGSGYSVDSEGSGGAAGETNLLPIPRIGKMGQNGQDLVKQPGMGATDTEAKTQVMGEIKLALKKEMKTDGEQLIVEILQCRNITYKFKSPDHLPDLYVKIYVINISTQKKVIKKKTRVCRHDREPSFNETFRFSLSPAGHSLQILLFSNGGKFMKKTLIGEACIWLDKVDLRKRIVNWHKLLVSPTQTH", "length": 5107, "header": "tr|A0A9J7HAQ6-1|A0A9J7HAQ6_CRIGR Isoform 1 of Protein piccolo OS=Cricetulus griseus OX=10029 GN=Pclo PE=4 SV=1 CANONICAL=A0A9J7HAQ6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HAQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAQ6/entry#A0A9J7HAQ6-1", "sequence": { "sequence": "MGNEASLEGEGLPEGLAAAAGGAGGSGSALHPGIPGGMEADLSQLSEEERRQIAAVMSRAQGLPEGSVPAAAAESPSMHRKQELESSQPPKQPGKPPDPGRPTQPGLSKSRTTDTFRAEQKLPGRSPSTISLKESKSRSDFKEEYKSSMMPGFLSDVNPLSAVSSVVNKFNPFDLISDSEASQEETTQKQKVAQKDQGKSEGITKPPLQQPSPKSVPKQGPAKEVIQQENALKSASSQQTEKIKPQLPSTGKPSQASSQLPPMDQAKLPIQRDTTRPQTKPSDLGKPSQQSPAKTPAQQASPGKSVAQQPGPAKASVQQPGSTKSPAPPAGTMKPPAQPPVTSKPPAQQVGVEKTLSQQPGPKSLAQTPGVGKIPPGPVKSPAQQPGTAKPPAQQPVLQPLVKVPGPAKTPAQQSGPGKTPAQQPGTAKPSPQQPLPAKPQPQQPLPAKPQPQQPLPAKPQPQQPLPAKPQPQKPLPAKPQPQQPTPAKPQPQQPTPAKPQPQQPTPAKPSAQQPVPPKPSAQQPVPPKPSAQQPMKPTSQTVTERPLQPPPPSAAQTPGQDISKTICPLCNTTELLLHIPDKANFNTCTECQTTVCSLCGFNPNPHLTEIKEWLCLNCQMQRALGGELAPIPSSPHPSPKAASVPPAVAASKPPVPSQPASPKKEPPPKQESPKAPELKKPPPLVKQPTLHGPATVTAPKPSVAEALPAASLPEQDKAPVPDVKPKQPKMAEQRADVQSSVAAATKSDVLSSQVQPQAQEQATPPLKTDSAKPSQSFPPTGEKITPFDSKALPRPSSDSKIISHPGPSSESKDLKHIDPTHKKEEPKKTQTKMSPKPDAKPVPKGSPTPSGPRPTTGQAVSPSQQSLKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPPPQTGPVVPTKPVPTPSQTPAAHGPPKSTGQFPPAPAKAMPVKKETKAPAAESSESKPEPALAVKKIEKDKKPPPGKVSKPPPAESESALLTHKPDKITKVEANCPLCKTELNIGSQEPPNFNTCTECKSQVCNLCGFNPTPHLTEIQEWLCLNCQTNRAISGQLGDMGKMPPVSSGSKASPVPAPADPSSQKTGSHMKGKKKETEVKTEAKKLIPEKETVSIEKTPPTVTTDEKLEETKLEKSKVSALQEKKSSSEEEKPRSEEKMGKEPSAEEKLASAEENPPLEGKKPTPEDKKLPPEVKPLALEGEEKHEILQAQVQIPEEKPTGSVVTKALQEEGQPEARTGDQPGHTPQPLPKQGEKESQAKQPQVEGSAKSDQVDPNKEKTEKEEDKSDTPSSQQPKSPQGLSDTGYSSDGISGSLGEIPSLIPSDEKDLLKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLSEKSEMKAQPQKVSPEQPRDAQKSQIPSDTQDITISEEEDKESQEKKESSKRDSQQGFPSRKDHKEKPELADDLSPRRASYDSVEDSSESENSPVAHRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRSQLKEIGGVTESHKREETKGKGKSAAGKHRRLTRKSSTSFDDDAGRRHSWHDEDDETYDESPELKFRETKSQESEELVVAGGGGLRRFKTIELNSAIADKYSAESSQKKTALYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKQESKQQRKARHRTHGPLLPTIEDSSEEEELREEEELLKEQEKQRELEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSVMQKEGVQKALKSAEEMYEEMMQKTHKYKAFPSANERDDVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEQNGFMQQRGREQKIRIPEQIYDDPMQKITDLQKEFYELESLHSVVPQEDIVSSSYIIPESHEIVDLGTMVTSTSEEKKLLDADTAYEELMRRQQMQVTDGSSPTQTTVGDDMAESAMDFDRVQDTSLTSSILSGASLTDSTSSATLSIPDVKITQHFSAEDLEDEYVTDYTREIQEMIAHESLILTYSEPSESAASVPPSDTPSLTSSISSVCTTDSSSPVTTLDSLTTAYTEPADVITKFEDSEEISSSTYFPGSIIDYPEDISVSLDRTTTPESRTNVDHIVISFSSIAPSVTESVGAKADRSQAVPMSTDSPICDKDPLKGKKETGDGIILEVLDAYTDKREESEAELTKISLPETGLVQTPSSFIAPQMKEQPVTPYSVSGKMSGQEKPTYRLPSASVPVSTHPSKSRPFFRSSSLDISAQPPPPPPPRPPPPFPPPPPPPLPPATSPKPTIYPKKKLAVAAPVTPTTVVTTHIDTITTVEATTARKSNGLPATKICATTPPPVPPKPSSIPTGLVFTHRPEPSKPPIAPKPAVPQIPVTTQKTTDTCPKPTALSLTSNMSLNLVTSADYKLPSPTSPLSPHSNKSSPRYSKSLMETYVVITLPSEPGTPTDSSAAQAITSWPLGSPPKDLVSLETVFSVVPAMTATEIPSSSQPTLYAPGTLETFSAAPVVTASLFQGAPTSPTKLLTTEASKTMVSTTRSAVPSIAPRSVSIPIPPEPLALDRHQYKENGNLQLIGDAIDLRTIPKTEAKATEKCMDLSASAMDVKRQTTANEVYGRQISAVQPSIMNLSAASSLVAPVTLDSETVAVVTGTAGTGSQVSVEHAMVSPLQLTTSKHTESPYRISSGQPFPMIRDEAPINLSLGPSAQPVTLAVTKPVTVPPVGVTNGWTDSTASQGIPDGEVVDLSTSKSHRTVVTMDESTSNVVTKIIEDDEKPVDLTAGRRAVCCDMVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNLAEAGHFFYKSKNAFDYSGGADAAVDLTSGRVTTGEVMDYSSKTTGPYPETRQVISGVGISTPQYSTARMTPPPGPQYGVGSVLRSSNGVVYSSVATPIPSTFAITTQPGSIFSTTVRDLSGIHTTDALTSLSALHQSQPMPRSYFITTGASETDISVTSMDINASLQTMTLETLPAETMDSVPALTTASEVFSEVVGEENTLLVVSEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQSMKQHLLYQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKLRQIYQYNYDPSGTASPQTTTEQAILEGPYAAQEGSQFWATEDATTTASTVVAIEIPQTQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKVRGQYEEMGESMADDPRNLKKIVDSGVQTDDEETADRSYASRRRKSKKSVDTSVQTDDEDQDEWDVPSRSRRKARPGKYGDSATEGDKPLSKVSSVAVQTVAEISVQTEPLGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTETDSDTQSPPYLGATSPPKDKKRPTPLEIGYSSSHLRADTTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPGSPKTAKMMQRSMSDPKPLSPTADESSRAPFQYSEGFTTKGSQTMTASGTQKKVKRTLPNPPPEEASTGTQSTYSTLGTASRRRMCRTNTMARAKILQDIDRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSSTRPSRIESQHGIERPRTAPQTEFSQFIPPQTQTEAQLVPPTSPYTQYQYSSPALPTQAPTPYTQQSHFQQQTLYHQQVSPYQTQPTFQAVATMSFTPQAQPTPSPQPSYQLPSQMMVIQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTYAVSHLGSKYNSLDLRIGLEERSSMVSSPISSISADSFYADIDHHTSRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRLLRTTETRRSQEVTDFLAPLQTSSRLHSYVKAEEDPMEDPYELKLLKQQIKQEFRRGTESLDHLAGLPHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPKMSKFSPIQESRDLEPDYPSYMSSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSLGSGLGTLGNTIRSALQDEADKSYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQEAEALDVSFGHSSSSSRTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEVAVAMYDVSLVSKAYHLRREETDWFDKPRESRLENGHVLDRKLPERLVHSRPLSQHQEQILQMNGKTMHYIFPHTRIKITRDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEHTGKLVEGMQVLEWNGIPLTSKTYEEVQSIINQQSGEAEICVRLDLNMLSDSENPQHLELHEPPKAVDKAKSPGVDPKQLAAELQKVSLQQSPLVMSSVVEKGSHAHSGPTSAGSSSVPSPGQPGSPSVSKKKHGSSKPTDATKVASHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGAEYKRRTKYVQKSLNPEWNQTVIYKSISMEQLMKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAAEAAVQQLRIQPTKPANHRPAESSVSTGSSGSSVGSGYSVDSEGSGGAAGETNLLPIPRIGKMGQNGQDLVKQPGMGATDTEAKTQVMGEIKLALKKEMKTDGEQLIVEILQCRNITYKFKSPDHLPDLYVKIYVINISTQKKVIKKKTRVCRHDREPSFNETFRFSLSPAGHSLQILLFSNGGKFMKKTLIGEACIWLDKVDLRKRIVNWHKLLVSPTQTH", "length": 5107, "header": "tr|A0A9J7HAQ6-1|A0A9J7HAQ6_CRIGR Isoform 1 of Protein piccolo OS=Cricetulus griseus OX=10029 GN=Pclo PE=4 SV=1 CANONICAL=A0A9J7HAQ6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1218, "start_aa": "Thr", "end_pos": 1218, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1218", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3906, "start_aa": "Thr", "end_pos": 3906, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3906", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 4631, "start_aa": "Thr", "end_pos": 4631, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4631", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAR3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAR3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772545", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772545", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HAR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAR3" }, { "id": "SM00993", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00993" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Vps72/YL1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 290, "end_pos": 319, "start_aa": "Glu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 242 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HAT4-1", "uniprot_ac": "A0A9J7HAT4", "uniprot_id": "A0A9J7HAT4_CRIGR", "mass": { "chemical_mass": 69033.0, "monoisotopic_mass": 69033.0 }, "refseq": { "ac": "XP_035305915", "name": "kelch-like protein 13", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305915" }, "gene_names": [ { "name": "Klhl13", "type": "recommended", "evidence": [ { "id": "A0A9J7HAT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAT4" } ] }, { "name": "Klhl13", "type": "synonym", "evidence": [ { "id": "XP_035305915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305915" } ] } ], "protein_names": [ { "name": "Kelch-like protein 13", "type": "synonym", "evidence": [ { "id": "A0A9J7HAT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAT4/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 13", "type": "synonym", "evidence": [ { "id": "XP_035305915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305915" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305915", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305915" } ] }, { "annotation": "Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAT4#function" }, { "database": "UniProtKB", "id": "ARBA00056604", "url": "https://www.uniprot.org/uniprotkb/ARBA00056604#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAT4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Klhl13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAT4", "locus": {} } ], "crossref": [ { "id": "A0A9J7HAT4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HAT4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18239", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18239", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18449", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18449", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764640", "url": "https://www.ncbi.nlm.nih.gov/gene/100764640", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764640", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764640", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HAT4", "url": "https://www.orthodb.org/?gene=A0A9J7HAT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305915", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305915", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HAT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLSLGSSEMGLSAHLQSCKAGSTRIFTSNTHSSVVLQGFEQLRHDGLLCDVTLLPGDTDDAFPVHRVMMASASDYFKAMFTGGMKEQELMCIKLHGVSKVGLRKIIDFIYTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLISGVTLDNCVEVGRIANTYHLTEVDKYVNTFVLKNFPALMGTGEFLKLPFERLAFVLSSNSLKQCTELDLFKATCRWLRLEEPRMDFAAKLMKNIRFPLMTPQELINYVQTVDFMRTDNTCVNLLLEASNYQMMPFMQPVMQSDRTAIRSDTTHLVTLGGVLRQQLVVSKELRMYDEKTHEWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWIQVASLNEKRTFFHLSALKGLLYAVGGRNAAGELPTVECYNPKTNEWTYVAKMNEPHYGHAGTVYGGVMYISGGITHDTFQKELMCFDPDTDKWTQKAPMTTVRGLHCMCTVGDRLYVIGGNHFRGTSDYDDVLSCEYYSPIHDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKDEWHKVFDLPESLGGIRACTLTVFPPESSTPSPSRESPLSAP", "length": 613, "header": "tr|A0A9J7HAT4-1|A0A9J7HAT4_CRIGR Isoform 1 of Kelch-like protein 13 OS=Cricetulus griseus OX=10029 GN=Klhl13 PE=4 SV=1 CANONICAL=A0A9J7HAT4-1" }, "isoforms": [ { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HAY2-1", "uniprot_ac": "A0A9J7HAY2", "uniprot_id": "A0A9J7HAY2_CRIGR", "mass": { "chemical_mass": 71320.0, "monoisotopic_mass": 71320.0 }, "refseq": { "ac": "XP_007640944", "name": "protection of telomeres protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640944" }, "gene_names": [ { "name": "Pot1", "type": "recommended", "evidence": [ { "id": "A0A9J7HAY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY2" } ] }, { "name": "Pot1", "type": "synonym", "evidence": [ { "id": "XP_007640944", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640944" } ] } ], "protein_names": [ { "name": "Protection of telomeres protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7HAY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY2/entry#names_and_taxonomy" } ] }, { "name": "POT1-like telomere end-binding protein", "type": "synonym", "evidence": [ { "id": "A0A9J7HAY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY2/entry#names_and_taxonomy" } ] }, { "name": "protection of telomeres protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007640944", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640944" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613878.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007640944", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640944" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pot1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY2", "locus": {} } ], "crossref": [ { "id": "cd04497", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04497", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04498", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04498", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20374", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20374", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758846", "url": "https://www.ncbi.nlm.nih.gov/gene/100758846", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028389", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028389", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758846", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758846", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NHVHLAK", "url": "https://omabrowser.org/oma/group/NHVHLAK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7HAY2", "url": "https://www.orthodb.org/?gene=A0A9J7HAY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14513", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14513", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14513:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14513:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21375", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21375", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007640944", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640944", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HAY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HB23", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HB23-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB23-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLVPVTPYTYTPLNLLKEGAIVNVYAVVKFFKPPYLSKGTDYCSVVTIVDQTNVKLTCMLFSGNYEALPIIYKVGDIVRFHRLKIQVYKNELQGINSSGFASLTFEGTLGTPVTARTSSKLFSFTPQDEKMVEALRVWASTHISASSTVVQLCDVQPMQYYDLTCQLLGKAEVDGTAFLLKVWDGTRTVFPSWRVSIQDLNFEGDLSHILRLQSLVIDILVYDNHVQVAKSLKIGSFLRIYSLHTKLHSVNTDTNSSLLRLEFHLHGGTSYGRGIRVLPETSSCVDQLKKDLEGADLAVNQPSNSQSANEDNFELSNSGSGSVSLYEVERCQQVSATILTDHQYLEKTPLCAILKQKAPQQYRIRAKLRSYMPRRLFQSVKLLCPKCHSLQEVPYENNLDKILQDAAAIAPNSKLQDTTLYDSKVWSTEGQGGRQVAVHFVKNDNILPLSSECLILIEGGRLCEVSKLSSKFHSVIPVRSGPEDLELLDLSAPFLIQGKVYHYGCKQCSNLKPIQNLNSLLNKGLWIPSAVAEVLGIVPLQYVFVMTFTLDDGTGVLDVYLKDSENFFKIPASEILTDDDHQRSLETIMNMICPPEIKIDAYPWLECLIKSYTVTLGTERRICYQIFDTTVAEDNI", "length": 637, "header": "tr|A0A9J7HAY2-1|A0A9J7HAY2_CRIGR Isoform 1 of Protection of telomeres protein 1 OS=Cricetulus griseus OX=10029 GN=Pot1 PE=3 SV=1 CANONICAL=A0A9J7HAY2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HAY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY2/entry#A0A9J7HAY2-1", "sequence": { "sequence": "MSLVPVTPYTYTPLNLLKEGAIVNVYAVVKFFKPPYLSKGTDYCSVVTIVDQTNVKLTCMLFSGNYEALPIIYKVGDIVRFHRLKIQVYKNELQGINSSGFASLTFEGTLGTPVTARTSSKLFSFTPQDEKMVEALRVWASTHISASSTVVQLCDVQPMQYYDLTCQLLGKAEVDGTAFLLKVWDGTRTVFPSWRVSIQDLNFEGDLSHILRLQSLVIDILVYDNHVQVAKSLKIGSFLRIYSLHTKLHSVNTDTNSSLLRLEFHLHGGTSYGRGIRVLPETSSCVDQLKKDLEGADLAVNQPSNSQSANEDNFELSNSGSGSVSLYEVERCQQVSATILTDHQYLEKTPLCAILKQKAPQQYRIRAKLRSYMPRRLFQSVKLLCPKCHSLQEVPYENNLDKILQDAAAIAPNSKLQDTTLYDSKVWSTEGQGGRQVAVHFVKNDNILPLSSECLILIEGGRLCEVSKLSSKFHSVIPVRSGPEDLELLDLSAPFLIQGKVYHYGCKQCSNLKPIQNLNSLLNKGLWIPSAVAEVLGIVPLQYVFVMTFTLDDGTGVLDVYLKDSENFFKIPASEILTDDDHQRSLETIMNMICPPEIKIDAYPWLECLIKSYTVTLGTERRICYQIFDTTVAEDNI", "length": 637, "header": "tr|A0A9J7HAY2-1|A0A9J7HAY2_CRIGR Isoform 1 of Protection of telomeres protein 1 OS=Cricetulus griseus OX=10029 GN=Pot1 PE=3 SV=1 CANONICAL=A0A9J7HAY2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HB23-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY2/entry#A0A9J7HB23-1", "sequence": { "sequence": "MSLVPVTPYTYTPLNLLKEGAIVNVYAVVKFFKPPYLSKGTDYCSVVTIVDQTNVKLTCMLFSGNYEALPIIYKVGDIVRFHRLKIQVYKNELQGINSSGFASLTFEGTLGTPVTARTSSKLFSFTPQDEKMVEALRVWASTHISASSTVVQLCDVQPMQYYDLTCQLLGKAEVDGTAFLLKIGSFLRIYSLHTKLHSVNTDTNSSLLRLEFHLHGGTSYGRGIRVLPETSSCVDQLKKDLEGADLAVNQPSNSQSANEDNFELSNSGSGSVSLYEVERCQQVSATILTDHQYLEKTPLCAILKQKAPQQYRIRAKLRSYMPRRLFQSVKLLCPKCHSLQEVPYENNLDKILQDAAAIAPNSKLQDTTLYDSKVWSTEGQGGRQVAVHFVKNDNILPLSSECLILIEGGRLCEVSKLSSKFHSVIPVRSGPEDLELLDLSAPFLIQGKVYHYGCKQCSNLKPIQNLNSLLNKGLWIPSAVAEVLGIVPLQYVFVMTFTLDDGTGVLDVYLKDSENFFKIPASEILTDDDHQRSLETIMNMICPPEIKIDAYPWLECLIKSYTVTLGTERRICYQIFDTTVAEDNI", "length": 585, "header": "tr|A0A9J7HB23-1|A0A9J7HB23_CRIGR Computationally mapped isoform of Protection of telomeres protein 1 OS=Cricetulus griseus OX=10029 GN=Pot1 PE=3 SV=1 CANONICAL=A0A9J7HAY2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758846", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758846", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JX31-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "Pot1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLVPVTPYTYTPLNLLKEGAVANVYGVVKFFKPPYLSKGTDYCSVVTIVDPTNVKLTCMLFSGNYEALPIIYKVGDIVRFHRLKIQVYKNELQGINSSGFASLTFEGTLGTPVTARTSSKVFSFTSQDQKMVEALRVWASKHIAASSSLVQLCDAQPLQYYDLTCQLLGKAEVDGTAFLLKVWDGTRTMFPSWRVSIQNLTFEGDLSHIQRLQSLVIDILVYDNHVQVAKSLKIGSFIRIYSLHTKLQSVDSETSKSLLRLEFHLHGGTSYGRGIRVLPDESSCVDQLKKDLECADSAVTQPSNGICQSKNEDSFVLSSSASGSVSLYEEERCQQVSSTILTDHQHLEKTPLCAVLKQKAPQQYRVRAKLRSYLPRRLPQSVKLICPQCHSLQEVPHEDSLDKLLQDAATKAPDIRLQGTSLYESKIWTTEGQGGRQVAVHFVKKDGVLPLSSECLILIEGGRLCEVSKLSSKFHSVIPVRSGPEDLELLDISAPFLIQGKLHHYGCKQCSSLKPIQNLNSLLNKGPWIPSSVAKVLGIVPLQYVFVMTFTLDDGTGVLDTYLKDSENFFKIPASEVLTDDNLQRNLEAIMDMICPPGIKVDAYPWLECLIKSYNVTIGTEQRICYQIFDTTVAEDV", "length": 638 }, "evidence": [ { "id": "A0A9J7HAY2", "url": "https://omabrowser.org/oma/group/A0A9J7HAY2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A287A5Z9-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLELIKEVNGVPQVDLLSKLHKIDFRSLQPDCDYSQKYIQGKLSLISSLTYGENKRAVLKIGLQEQENSNAEINTINILLFGKLAKDCAKVFYDGDTIAVAGFVVLSAASTSKDGKHSLFLKASEDFQSTVYVYVKSVRDFSTESMSLVPATHYIYTPLNQLKGGMIVNVYGVVKFFKPPYLSRGTDYCSVVTIVDQTNVKLTCLFFSGNYEALPVIYKNGDIVRFHRLKIQVYKKETQGITSSGFASLTFEGTLGAPIIPRTSSKCFNFTTEDHKMVEALRVWASTHISPSSTLVKLCDVQPMQYFDLTCQLLGKAEVDGASYLLKVWDGTKTPFPSWRVLIQDLVFEGDLDHIHRLQNLTIDILVYDNHVQVAKSLKVGSFLRIYSLHTKLQSVNSENTATFLALEFHLHGGTSYGRGIRVLPESNSDVDQLKKVLESADLPASQCLDGICQSQQEDTFSNISSSGSVSLYEVERCQQLSATILTDHQYLEKTPLCAILKQKAPQQYRVRAKLRSYKPRRLFQSVKLYCPKCHSLQEVPHEGDLDIILQEGANKTPDTKLQNTSLYDSKIWTTKDQGERKVAIHFVKNNGILPLSNDCLILIEGGTLSEICKLSKKFHSVIPVRSGHEDLELLNLSAPFLIQGKIHHYGCKQCSHLRSIQNLNSLADKTTWIPSSVAEVLGIVPLQHVFVMTFTLDDGTGVLEAYLMDSEKFFQIPASEVLLSDNLQEIMDMIMDMFCPTGAKIDAYPWLECFIKSYNVTSGTEQQICYQIFDTTVAEDLI", "length": 784 }, "evidence": [ { "id": "A0A9J7HAY2", "url": "https://omabrowser.org/oma/group/A0A9J7HAY2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0X9W5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMGGSIQVVGILCSVFFSMVFMRKLNRKWASEISRFGSPHQLDAVVLGCSFILRDILIAAMPVQVLKIIKGKLETQLPSHLQREDLKHLQTGLDHTNKYFQGIVILSYPLTKLGDGTDFFKIVLQDDTCSRINSINVLMYGKMAEDCAKLIRNGDTFIVAGFKVAESPTAREDGRHACHLQVSEESGSAIFICTQPSITPFSEATSPSVAPKYVYTPLNCLKDGTVVNLYGIVKFFKPPYISKGTDYCSVVTLVDQSNVKLTCTLFNGNLDSLPKIYKNGDIVRFHRVKIREYNGQMQGITSAGFASLTFDGTVGAPVVPRASSKVYTFVDEEQKTVEELRIWAASNLSVSGPEAKLSDVKPMMFFDLTCQLVGKAKVDGSSFLLKVWDGTKCPYPTWKVPVEAKELEGDRVLLHHLRNLTVDVLVYDNHVQLAKSLKTGSFLRIYSIHTKQASAKNEDISSHIEFHLHGGTCYGRGIGILPENNPDVEELKSFLECVELTDSQNMESVSSLELGDTFDSYTDLESPLQRCQQLSATVLTDHQDMSNTVLKTVLNSSAPQQYRIRAKLRSFKPQKLYQSVKLHCSKCNTLQEVPNGDAIDFILQGCAATAPNPELQSMSWYESVVWTTEEDQGRKITIHFVKHYEMLQRPENTLLMIEGGTLKEIWKLTRRFKCVIPVKSKEDDLELLDLSAPFLLQGNIKYYGCKKCSTPKSIKNLSSLAEKREPSWEPTEIAQVLGIEPLQYVFVMKFTLVDGTGVLNAYLFDYEKFFQIPASEILTNSFLQQKMEMTMNTLSPPGRKLDDLPWLECFIKSYNVADGMKHQVYYQIFDTTVAEDVV", "length": 838 }, "evidence": [ { "id": "A0A9J7HAY2", "url": "https://omabrowser.org/oma/group/A0A9J7HAY2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7F0D5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "pot1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPVEKVNNSSDLDTKVPSCLQLTSIGQLTLTSDPSHRCVKARVLRKGPVISCAQRDGLEMLRAEIREEDPLQSTTEHTSINVIFFDTLAKDFSQSVKQGDIVLLANFTISKSPTFLRDKLHPCQLEMDNKDACVYVCPSAIPGPSSSEAKYVYVPLNKLKSKTLVNVYGVVTFFKQPFPSKGSDYCTTLKITDQSDVKVICTIFCKKLEDHPLIFRVGDIIRLHRFKAEAFRDSITLINTFGWSTVTFNGIIDSPIVPRTSSKSFFYGEADKRRVQELRQWAANQSLCSDLNTSLSSVQPHMYFDFTCQLLAKAVMHSGCILLKVWDGTRCQLPLLQVAVPPDELEGECTLAKDKMNLTANVLVYDNHLEVARDLKPGAFLRFYNLRALLQKVPGQLPDQPEHLGFHLHGGTVYGRGLRSLPAETPDLLSLKSVLEKHVDLDEHEEVNDGTLLEIWYTPPESIVLPNDENPGAEENAGPAYTVQTCEHNTQRITLAQVKRSTPPLSCHVRARVKKYLPQQLYQCLKLFCSKCKTMKDVPDDSAVANIFLESARDNQPCDEQWAATSSANSREPGRTISMHVSKDMVGKSSHMQLIFIEGMTLDEISVLSRDHKNLVPVRSENSKMTRMDLTAPFLFSGKKRYYGCKQCSRNTFENPVFTGVETWDEQAVAAVLGVQMMQYRFLIQFELDDVTDTIEALLWEDAERFFHISAVDASGCQDLQDRIQTIMDTIQPPESSLEERPWMDFCLSVYTVKDNDRNKVCYQITNTEIVKQ", "length": 773 }, "evidence": [ { "id": "A0A9J7HAY2", "url": "https://omabrowser.org/oma/group/A0A9J7HAY2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q91WC1-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "Pot1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLVSTAPYTYTPLNLLKEGTIANVYGVVKFFKPPYVSKGTDYCSVVTIVDQTNVKLTCMLFSGNYEALPIIYKVGDIVRFHRLKIQVYKNELQGINCSGFASLTFEGTVGMPVTARTSSKVFSFTPQDQKMVEALRVWASKHISASSTLVQLCDAQPMQYYDLTCQLLGKAQVDSTAFLLKVWDGTQTVLPSWRVSTQDLTFEGDLSHIERLQSLVVDILVYDNHVQVARSIEVGCFLRLYSLHTKLQPGNSETSSSESLRLEFHLHGGTSYGRGIRVLPDTSPCVDQLKKALEGANLPVTETSTGICQSENGDSSALSNSGSGAVSPYEEERCQQVSATILTNHQHLEKTPLCAILTQKAPQQYRVRAKLRSYLPRRLSQSVKLLCPKCHSVQEVPHGDSLDKILQDAATEAPDIKLKATSLYYSKVWTTEDQGGRQVAVHFVKNNGILPASSECLILIEGGRLCEVSKLSSKFHSVMPVRSGPESLELLTLSAPFLIQGKVHHYGCKQCSSLKPIQNLNSRFHKGPWTPSSVAEALGVVPLQYVFVMVFTLDDGTGVLEAYLKDSEHFFKIPASEVLTDDDLQRSLETIMDMICPPGIKVDAYPWLECLLKSYNVTIGTERRICYQIFDTTVAENVV", "length": 640 }, "evidence": [ { "id": "A0A9J7HAY2", "url": "https://omabrowser.org/oma/group/A0A9J7HAY2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { 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"url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098505", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY2" } ], "pmid": "" }, { "name": "telomerase inhibitor activity", "id": "GO:0010521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010521", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY2" } ], "pmid": "" }, { "name": "nuclear telomere cap complex", "id": "GO:0000783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000783", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY2" } ], "pmid": "" } ] }, { 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"uniprot_canonical_ac": "A0A9J7HAY7-1", "uniprot_ac": "A0A9J7HAY7", "uniprot_id": "A0A9J7HAY7_CRIGR", "mass": { "chemical_mass": 21624.0, "monoisotopic_mass": 21624.0 }, "refseq": { "ac": "XP_035308711", "name": "motile sperm domain-containing protein 1-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308711" }, "gene_names": [ { "name": "LOC100756773", "type": "recommended", "evidence": [ { "id": "A0A9J7HAY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY7" } ] }, { "name": "LOC100756773", "type": "synonym", "evidence": [ { "id": "XP_035308711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308711" } ] } ], "protein_names": [ { "name": "Motile sperm domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7HAY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY7/entry#names_and_taxonomy" } ] }, { "name": "motile sperm domain-containing protein 1-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035308711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308711" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308711", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308711" } ] }, { "annotation": "Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY7#function" }, { "database": "UniProtKB", "id": "ARBA00045707", "url": "https://www.uniprot.org/uniprotkb/ARBA00045707#function" }, { "database": "UniProtKB", "id": "A0A9J7HB69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB69#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100756773", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY7", "locus": {} } ], "crossref": [ { "id": "A0A9J7HAY7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HAY7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100756773", "url": "https://www.ncbi.nlm.nih.gov/gene/100756773", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000535", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000535", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008962", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008962", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756773", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756773", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HB69", "url": "https://www.orthodb.org/?gene=A0A9J7HB69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34441", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34441", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34441:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34441:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00635", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00635", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308711", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308711", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HB69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HB69-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHQQKRQPELVEGNLPVFVFPTELIFYADDQSTHKQVLTLYKPYEFALKFKVLCTTPNKYVVVDAAGAVKPQCCVEIVIRHRDVRSCHYGVIDKFCLQVSEQSQRKALGRKEVIATLLPSAKEQQKEEEERRIKEHLTESVFFEQSCQPENITVSSGPSLLTVLLGVVCIVALMLPTLGIWNRWCLSTST", "length": 190, "header": "tr|A0A9J7HAY7-1|A0A9J7HAY7_CRIGR Isoform 1 of Motile sperm domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=LOC100756773 PE=4 SV=1 CANONICAL=A0A9J7HAY7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HAY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY7/entry#A0A9J7HAY7-1", "sequence": { "sequence": 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756773", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756773", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HAY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAY7" }, { "id": "PF00635", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00635" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MSP", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 110, "start_aa": "Val", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 24% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. 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##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307260", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307260" } ] }, { "annotation": "Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. Slow skeletal protein that binds to both myosin and actin. In vitro, binds to native thin filaments and modifies the activity of actin-activated myosin ATPase. 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Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 7% of CDS bases frameshifts :: corrected 1 indel internal stop codons :: corrected 3 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307301", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307301" } ] }, { "annotation": "Involved in pre-mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB46#function" }, { "database": "UniProtKB", "id": "RU367071", "url": "https://www.uniprot.org/uniprotkb/RU367071#function" } ] }, { "annotation": "Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB46#function" }, { "database": "UniProtKB", "id": "ARBA00045201", "url": "https://www.uniprot.org/uniprotkb/ARBA00045201#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB46" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100754137", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB46", "locus": {} } ], "crossref": [ { "id": "100754137", "url": "https://www.ncbi.nlm.nih.gov/gene/100754137", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754137", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754137", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HB46", "url": "https://www.orthodb.org/?gene=A0A9J7HB46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12942", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12942", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12942:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12942:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11708", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11708", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307301", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307301", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HB46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HB46-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALFTLNFLNIDAQGHTAAKRHTSEPKRPKELLLDHRGSQFILLATAVDTVNATPMSGSKEMXLEEPKKMTREDRRKNTELEEQRKLGNATAEVDEEGKDINPHIPQYISSVAWYIDPSKTPTLKHQRKQPEKEKQFSSSREWYKRGVKENSVSTKYGKGACENGGAMTHKNEDCFKRPRRVGANFTGTSIAPEEHIQPQLMFDYGGKRDXRNAYSSEEPVETVEEYNKLYLAKXSLKTLKLKEELASGKLMGQANSPKHQWGQEEPNSQKKKDHNSEKEDEDKYADDIDMPGQNFISKRYITVQNLRIREDTAKFRNLDPNSAYYNPKTRAMREYPYVNTGKNPDEVSYAGDNCVRYTGDTCSMAQTQLFTWEAYGKGTEVHLQADPTKLELLYTSFKVKKEDFKEQQNESILEKYGGQEHLDAAPAELLLAQTDYVEYSRHGTVMKGQERTVACSKYEEDVKIHNHMHIWGSYWKEGQXGYKCCHSFFKYSYCTGGTGKERVHSEECIINGATGEESVMRPQTLMQLHQEKLNPHEKKKKKRKKHQKSSSHSDKDRKHKKRKKAVNAEETRLLHVKEIMQIDEWKRPYSSICETQEPNEEEMEAYRMKQQRPDDPMVSFLGYSHR", "length": 627, "header": "tr|A0A9J7HB46-1|A0A9J7HB46_CRIGR Isoform 1 of Pre-mRNA-splicing factor SLU7 OS=Cricetulus griseus OX=10029 GN=LOC100754137 PE=3 SV=1 CANONICAL=A0A9J7HB46-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HB46-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB46/entry#A0A9J7HB46-1", "sequence": { "sequence": "MALFTLNFLNIDAQGHTAAKRHTSEPKRPKELLLDHRGSQFILLATAVDTVNATPMSGSKEMXLEEPKKMTREDRRKNTELEEQRKLGNATAEVDEEGKDINPHIPQYISSVAWYIDPSKTPTLKHQRKQPEKEKQFSSSREWYKRGVKENSVSTKYGKGACENGGAMTHKNEDCFKRPRRVGANFTGTSIAPEEHIQPQLMFDYGGKRDXRNAYSSEEPVETVEEYNKLYLAKXSLKTLKLKEELASGKLMGQANSPKHQWGQEEPNSQKKKDHNSEKEDEDKYADDIDMPGQNFISKRYITVQNLRIREDTAKFRNLDPNSAYYNPKTRAMREYPYVNTGKNPDEVSYAGDNCVRYTGDTCSMAQTQLFTWEAYGKGTEVHLQADPTKLELLYTSFKVKKEDFKEQQNESILEKYGGQEHLDAAPAELLLAQTDYVEYSRHGTVMKGQERTVACSKYEEDVKIHNHMHIWGSYWKEGQXGYKCCHSFFKYSYCTGGTGKERVHSEECIINGATGEESVMRPQTLMQLHQEKLNPHEKKKKKRKKHQKSSSHSDKDRKHKKRKKAVNAEETRLLHVKEIMQIDEWKRPYSSICETQEPNEEEMEAYRMKQQRPDDPMVSFLGYSHR", "length": 627, "header": "tr|A0A9J7HB46-1|A0A9J7HB46_CRIGR Isoform 1 of Pre-mRNA-splicing factor SLU7 OS=Cricetulus griseus OX=10029 GN=LOC100754137 PE=3 SV=1 CANONICAL=A0A9J7HB46-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB46" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754137", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754137", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB46" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB46" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "pre-mRNA 3'-splice site binding", "id": "GO:0030628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030628", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], 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"authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HB48-1", "uniprot_ac": "A0A9J7HB48", "uniprot_id": "A0A9J7HB48_CRIGR", "mass": { "chemical_mass": 74465.0, "monoisotopic_mass": 74465.0 }, "refseq": { "ac": "XP_035308951", "name": "ATP-binding cassette sub-family G member 3-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308951" }, "gene_names": [ { "name": "LOC100769836", "type": "recommended", "evidence": [ { "id": "A0A9J7HB48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB48" } ] }, { "name": "LOC100769836", "type": "synonym", "evidence": [ { "id": "XP_035308951", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308951" } ] } ], "protein_names": [ { "name": "ATP-binding cassette sub-family G member 3-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035308951", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308951" }, { "id": "A0A9J7HB48", "database": 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308951", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308951" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB48" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100769836", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB48", "locus": {} } ], "crossref": [ { "id": "A0A9J7HB48", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HB48", "database": "AlphaFoldDB", "categories": [] }, { "id": "100769836", "url": "https://www.ncbi.nlm.nih.gov/gene/100769836", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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##RefSeq-Attributes-START## ab initio :: 13% of CDS bases internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307339" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB66", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB66#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB66", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB66" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113832509", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB66", "locus": {} } ], "crossref": [ { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113832509", "url": "https://www.ncbi.nlm.nih.gov/gene/113832509", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113832509", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113832509", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HB66", "url": "https://www.orthodb.org/?gene=A0A9J7HB66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24377", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24377", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307339", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HB66", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HB66-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTENAVTYDDVRVNFTPDEWAILDPFQKNLYKEVMLDTYKNLTDIGYNLKDHNIEEPDQISTQHGRHEKRHIGEYIHCGKAFASLHYLQMQKSTHSQKKPYECTQCGKRFVNTRYLQVHKRTHTGKKSYTCNQCDKVFAYHGSLKKHKKTHSGEKPYKCNQCDKAFARHDNLQQHKRTHTGEKPYKCNQCEKAFARQSSMSIHKRTHSGEKPYKCNQCDKAFAHCSTLQDHKRTHNGEKPYKCNQCGKAFSRQSALQIHKRIHSGEKCYKCNQCDKAFVQPSSLQNHKRTHTGEKPYKCNQCDKAFVQPNSLQRHKRTHTGEKPYKCNQCDKDFPQKRHFQIHKRTCTGEKPXKCNQYSKAFAHKNNL", "length": 368, "header": "tr|A0A9J7HB66-1|A0A9J7HB66_CRIGR Isoform 1 of LOW QUALITY PROTEIN: zinc finger protein 431-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC113832509 PE=3 SV=1 CANONICAL=A0A9J7HB66-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HB66-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB66/entry#A0A9J7HB66-1", "sequence": { "sequence": "MTENAVTYDDVRVNFTPDEWAILDPFQKNLYKEVMLDTYKNLTDIGYNLKDHNIEEPDQISTQHGRHEKRHIGEYIHCGKAFASLHYLQMQKSTHSQKKPYECTQCGKRFVNTRYLQVHKRTHTGKKSYTCNQCDKVFAYHGSLKKHKKTHSGEKPYKCNQCDKAFARHDNLQQHKRTHTGEKPYKCNQCEKAFARQSSMSIHKRTHSGEKPYKCNQCDKAFAHCSTLQDHKRTHNGEKPYKCNQCGKAFSRQSALQIHKRIHSGEKCYKCNQCDKAFVQPSSLQNHKRTHTGEKPYKCNQCDKAFVQPNSLQRHKRTHTGEKPYKCNQCDKDFPQKRHFQIHKRTCTGEKPXKCNQYSKAFAHKNNL", "length": 368, "header": "tr|A0A9J7HB66-1|A0A9J7HB66_CRIGR Isoform 1 of LOW QUALITY PROTEIN: zinc finger protein 431-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC113832509 PE=3 SV=1 CANONICAL=A0A9J7HB66-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB66", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB66" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB66", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB66" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113832509", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113832509", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB66", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB66" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB66", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB66" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB66", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB66" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB66", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB66" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB66", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB66" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB66" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 101, "end_pos": 128, "start_aa": "Tyr", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7HB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB66" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 82, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 41, "end_pos": 43 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HB77-1", "uniprot_ac": "A0A9J7HB77", "uniprot_id": "A0A9J7HB77_CRIGR", "mass": { "chemical_mass": 106845.0, "monoisotopic_mass": 106845.0 }, "refseq": { "ac": "XP_035307355", "name": "kinesin-like protein KIF6 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307355" }, "gene_names": [ { "name": "Kif6", "type": "recommended", "evidence": [ { "id": "A0A9J7HB77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB77" } ] }, { "name": "Kif6", "type": "synonym", "evidence": [ { "id": "XP_035307355", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307355" } ] } ], "protein_names": [ { "name": "Kinesin-like protein", "type": "recommended", "evidence": [ { "id": "A0A9J7HB77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB77/entry#names_and_taxonomy" } ] }, { "name": "kinesin-like protein KIF6 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035307355", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307355" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 17% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307355", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307355" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HB77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB77" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Kif6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB77", "locus": {} } ], "crossref": [ { "id": "A0A9J7HB77", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HB77", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01375", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01375", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770243", "url": "https://www.ncbi.nlm.nih.gov/gene/100770243", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770243", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770243", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HB77", "url": "https://www.orthodb.org/?gene=A0A9J7HB77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47968", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47968", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47968:SF67", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47968:SF67", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23735", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23735", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307355", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307355", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HB77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HB77-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKQTIQIFARVKPSMRKQQQGIYSIDEDEKLTPSLEILLPRDLADGFVNNKRENYRFKFQRIFDQDAKQEIIFEIIAKPVAESVLSGYNGTIFAYGQTGSGKTFTITGGAERYSDRGIIPRTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASKLEDLPKVTILEDPDQNIHLKNLSLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLTSKEPGSATVRHAKLHLVDLAGSERVAKTGVGGLLLTEAKYINLSLHYLEQVIIALSEKHRTHIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNIDESISTCRFAQRVALIKNEAVLNEEIDPRLMIIRLQKEISDLKTELAMATGEWKTEELSKAELLQLEKLIASFLEDQDPESRLEVGADMRKIHHCFHHFKKLLNDKNTMKNTISSETTHQACQEPLKDEEYTKLRDLLKQRDNEINILVNMLKKEKKKTQDALHLSSKEMSETRTAQNSPFIPKSPAGQSTAVSSALYQAQDLSTCRRRSSLLHKKTGMREEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQRFSEAKALGESINETRNKIGQLKDAITQRHLQQVALGISENSVTPSMPDLQEEKLRAQLEEEKTRYKMTFMRLKALKVEIEHLQLLMDKAKVKLQKEFQVWWTEEANNLQANSPTTNPQEHLKPLPQQDQPQLVSKKRRNVGLLLGKSTHQAVMLNGPNTSGELPDVDPPSVSMQRSSETTQGQQCGQGKIASASLECQQGPATTDGCTDTGKLKVIVSPKDSLEPPYNLMSQERMEGDVYQGWEPEDVVDNLDVCDRNARRIIPSPCPSQYSQGPSGSRTQLQDSIPERPMSSIPLTGDSQTDSDILAFIKARQSILQKKWLPHSLSFLLPICGLEGIRLHVDGALELKENCHAHIRQLDCH", "length": 945, "header": 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Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616100.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 18, 2018 this sequence version replaced XP_016818726.1. 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. 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"evidence": [ { "id": "A0A9J7HBI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBI3/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: CXXC-type zinc finger protein 4-like", "type": "synonym", "evidence": [ { "id": "XP_035307032", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307032" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307032" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBI3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBI3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113833499", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBI3", "locus": {} } ], "crossref": [ { "id": "113833499", "url": "https://www.ncbi.nlm.nih.gov/gene/113833499", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113833499", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113833499", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HBI3", "url": "https://www.orthodb.org/?gene=A0A9J7HBI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13419", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13419:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13419:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307032", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HBI3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBI3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNTNVCVEPGPSPEAPGLPKESHLPEGALNSLVDYNSEMERYRSFATSFYKTNGGAFPQAAKIARITTPIFPSSAAAAAAAARIGMSPWNCDNAATAAATAMLWGSGGRRRGGGGGGGGGGGAGAGRKSSSAAASASASSSAILXAAGGGGGSGGGGGGGRTSMHHRNDSQRLGKAGCPPEPSLQMANTNFLSTLSPEHCRPLAGECMNKLKCGAAEAEIMNLPERVGTFSAIPALGGISLPPGVIVMTALHSPAAASAAVTDSAFQIANLADCPQNHSSSSSSSSGGAGGANPAKKKRKRCGVCVPCKRLINCGVCSSCRNRKTGHQICKFRKCEELKKKPGTSLERTPVPSAEAFRWFF", "length": 361, "header": "tr|A0A9J7HBI3-1|A0A9J7HBI3_CRIGR Isoform 1 of CXXC-type zinc finger protein 4 OS=Cricetulus griseus OX=10029 GN=LOC113833499 PE=4 SV=1 CANONICAL=A0A9J7HBI3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HBI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBI3/entry#A0A9J7HBI3-1", "sequence": { "sequence": "MNTNVCVEPGPSPEAPGLPKESHLPEGALNSLVDYNSEMERYRSFATSFYKTNGGAFPQAAKIARITTPIFPSSAAAAAAAARIGMSPWNCDNAATAAATAMLWGSGGRRRGGGGGGGGGGGAGAGRKSSSAAASASASSSAILXAAGGGGGSGGGGGGGRTSMHHRNDSQRLGKAGCPPEPSLQMANTNFLSTLSPEHCRPLAGECMNKLKCGAAEAEIMNLPERVGTFSAIPALGGISLPPGVIVMTALHSPAAASAAVTDSAFQIANLADCPQNHSSSSSSSSGGAGGANPAKKKRKRCGVCVPCKRLINCGVCSSCRNRKTGHQICKFRKCEELKKKPGTSLERTPVPSAEAFRWFF", "length": 361, "header": "tr|A0A9J7HBI3-1|A0A9J7HBI3_CRIGR Isoform 1 of CXXC-type zinc finger protein 4 OS=Cricetulus griseus OX=10029 GN=LOC113833499 PE=4 SV=1 CANONICAL=A0A9J7HBI3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"Protein Classification" ] }, { "id": "IPR047253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762639", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762639", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HBK7", "url": "https://www.orthodb.org/?gene=A0A9J7HBK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45983", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45983", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45983:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45983:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307198", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307198", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HBK7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQREILQRLLNEAQKKKINNEEFANEFLKLKRQSTKYKADKTYPTTVAQRPKNIKKNRYKDILPYDHSLVELSLITSDEDSSYINANFIKGVYGPRAYIATQGPLSTTVLDFWRMIWEYRILVIVMACMEFEMGKKKCERYWAEPGETQLQFGPFSIFCEAEKKKSDYIIRTLKVKFNNKTRIVYQFHYKNWPDHDVPSSIDPILELIWDIRCYQEDDCVPICVHCSAGCGRTGVICAIDYTRMLLKDGIVPENFSVFSLIQEMRTQRPSLVQTQEQYELVYNAVLELFKRHMDIIGDEPSGREIEAESSVPDSCSPDLPKNATKDAKTTKQQSEQRVQAESADTSSVDRISEISAKDFVLRSAKSSPSFDFLELNCGCNNKAVITREGQAKASPIVGEPLQKYQSLDFGSILCGSCPGAPPINTADRCRNSRTPVIRTKSTPFELIQQRKTHELDMEDCSLFLESQLHEPCLVELQAQKVVHVSSEELNYSLPRASEQQTCDIPCVPQHSPNTFRVRSCMSLVEDPYFPSSPPNSADSKMSFDLPENQDGATFPCALLPVSPTTPLSYCNSHDSLMSSPVASFPLTLNQETAKEATSLRLDDEIPPPLPERTPESFIVAEEAGEYLHQDGSPPPPLPERTLESFFLADEDCLQAKPIETYSTSYPETTENSISSKQTLKTPGKSFTRSKSLKIFRNMKKSVCNSSPSSKPAECVQPKNSSSFLNFGFGNRFSKPKGPRNPPSTWNI", "length": 748, "header": "tr|A0A9J7HBK7-1|A0A9J7HBK7_CRIGR Isoform 1 of protein-tyrosine-phosphatase OS=Cricetulus griseus OX=10029 GN=Ptpn22 PE=3 SV=1 CANONICAL=A0A9J7HBK7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HBK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7/entry#A0A9J7HBK7-1", "sequence": { "sequence": "MDQREILQRLLNEAQKKKINNEEFANEFLKLKRQSTKYKADKTYPTTVAQRPKNIKKNRYKDILPYDHSLVELSLITSDEDSSYINANFIKGVYGPRAYIATQGPLSTTVLDFWRMIWEYRILVIVMACMEFEMGKKKCERYWAEPGETQLQFGPFSIFCEAEKKKSDYIIRTLKVKFNNKTRIVYQFHYKNWPDHDVPSSIDPILELIWDIRCYQEDDCVPICVHCSAGCGRTGVICAIDYTRMLLKDGIVPENFSVFSLIQEMRTQRPSLVQTQEQYELVYNAVLELFKRHMDIIGDEPSGREIEAESSVPDSCSPDLPKNATKDAKTTKQQSEQRVQAESADTSSVDRISEISAKDFVLRSAKSSPSFDFLELNCGCNNKAVITREGQAKASPIVGEPLQKYQSLDFGSILCGSCPGAPPINTADRCRNSRTPVIRTKSTPFELIQQRKTHELDMEDCSLFLESQLHEPCLVELQAQKVVHVSSEELNYSLPRASEQQTCDIPCVPQHSPNTFRVRSCMSLVEDPYFPSSPPNSADSKMSFDLPENQDGATFPCALLPVSPTTPLSYCNSHDSLMSSPVASFPLTLNQETAKEATSLRLDDEIPPPLPERTPESFIVAEEAGEYLHQDGSPPPPLPERTLESFFLADEDCLQAKPIETYSTSYPETTENSISSKQTLKTPGKSFTRSKSLKIFRNMKKSVCNSSPSSKPAECVQPKNSSSFLNFGFGNRFSKPKGPRNPPSTWNI", "length": 748, "header": "tr|A0A9J7HBK7-1|A0A9J7HBK7_CRIGR Isoform 1 of protein-tyrosine-phosphatase OS=Cricetulus griseus OX=10029 GN=Ptpn22 PE=3 SV=1 CANONICAL=A0A9J7HBK7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 565, "start_aa": "Thr", "end_pos": 565, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr565", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBK7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBK7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762639", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762639", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBK7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBK7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBK7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ], "pmid": "" }, { "name": "negative regulation of T cell activation", "id": "GO:0050868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050868", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBK7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "non-membrane spanning protein tyrosine phosphatase activity", "id": "GO:0004726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004726", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBK7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 705, "end_pos": 707, "annotation": "n_glycosylation_sequon" }, { "start_pos": 720, "end_pos": 722, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3H060-1", "G3H622-1", "G3H9Q0-1", "A0A8C2LH05-1", "G3HKY7-1", "G3GWQ6-1", "G3HBF6-1", "G3GRD1-1", "G3H8H2-1", "A0A9J7FG56-1", "A0A061IAM9-1", "A0A9J7GE78-1", "A0A9J7GZK0-1", "A0A061HX98-1", "A0A061HZS8-1", "A0A3L7HEJ5-1", "A0A8C2LYZ8-1", "A0A9J7JC04-1", "A0A8C2MQ28-1", "A0A3L7I231-1", "A0A9J7EY47-1", "A0A8C2LVB9-1", "A0A8C2MZ43-1", "A0A9J7G003-1", "A0A8C2QC02-1", "A0A9J7JD11-1", "A0A8C2QH88-1", "A0A9J7EXY7-1", "A0A9J7JC62-1", "A0A9J7FEN1-1", "A0A9J7FB56-1", "A0A9J7FEZ5-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FWX7-1", "A0A9J7G1A0-1", "A0A9J7JTT7-1", "A0A9J7G7L1-1", "A0A9J7G7K2-1", "A0A9J7GNR2-1", "A0A9J7JU39-1", "A0A9J7KAX8-1", "A0A9J7GQG9-1", "A0A9J7GX92-1", "A0A9J7F2A0-1", "A0A9J7EZC9-1", "A0A9J7EZL1-1", "A0A9J7FIV0-1", "A0A8C2MFV5-1", "A0A8C2N2E5-1", "A0A8C2N686-1", "A0A8C2QCP2-1", "A0A3L7IA07-1", "A0A9J7FYL8-1", "A0A9J7G168-1", "A0A9J7GBQ5-1", "A0A9J7H7L7-1", "A0A9J7HBK7-1", "A0A9J7GQC8-1", "A0A9J7H152-1", "A0A9J7KDA7-1", "A0A9J7KDM0-1", "A0A9J7J766-1", "A0A9J7FKB3-1", "A0A3L7HAL2-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HX98", "gene_name": "Dusp9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] } ] }, { "uniprot_ac": "A0A061HZS8", "gene_name": "Ptpn14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HZS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZS8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HZS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZS8" } ] } ] }, { "uniprot_ac": "A0A061IAM9", "gene_name": "LOC100766206", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] } ] }, { "uniprot_ac": "A0A3L7HAL2", "gene_name": "Pgp", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] } ] }, { "uniprot_ac": "A0A3L7HEJ5", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] } ] }, { "uniprot_ac": "A0A3L7I231", "gene_name": "Ptp4a3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] } ] }, { "uniprot_ac": "A0A3L7IA07", "gene_name": "Ptp4a2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] } ] }, { "uniprot_ac": "A0A8C2LH05", "gene_name": "Acp1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] } ] }, { "uniprot_ac": "A0A8C2LVB9", "gene_name": "Dusp22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] } ] }, { "uniprot_ac": "A0A8C2LYZ8", "gene_name": "Ptprf", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] } ] }, { "uniprot_ac": "A0A8C2MFV5", "gene_name": "LOC100758361", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] } ] }, { "uniprot_ac": "A0A8C2MQ28", "gene_name": "Ptprz1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] } ] }, { "uniprot_ac": "A0A8C2MZ43", "gene_name": "Ptprg", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] } ] }, { "uniprot_ac": "A0A8C2N2E5", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] } ] }, { "uniprot_ac": "A0A8C2N686", "gene_name": "Ptp4a1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ] } ] }, { "uniprot_ac": "A0A8C2QC02", "gene_name": "Ptpn6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] } ] }, { "uniprot_ac": "A0A8C2QCP2", "gene_name": "Dusp28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] } ] }, { "uniprot_ac": "A0A8C2QH88", "gene_name": "Dusp12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] } ] }, { "uniprot_ac": "A0A9J7EXY7", "gene_name": "Ptpn13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] } ] }, { "uniprot_ac": "A0A9J7EY47", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] } ] }, { "uniprot_ac": "A0A9J7EZC9", "gene_name": "Ptpn18", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] } ] }, { "uniprot_ac": "A0A9J7EZL1", "gene_name": "LOC113830718", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] } ] }, { "uniprot_ac": "A0A9J7F2A0", "gene_name": "Ptpn12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7F2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2A0" } ] } ] }, { "uniprot_ac": "A0A9J7FB56", "gene_name": "Ptpru", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FB56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FB56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB56" } ] } ] }, { "uniprot_ac": "A0A9J7FEN1", "gene_name": "Eya1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] } ] }, { "uniprot_ac": "A0A9J7FEZ5", "gene_name": "Ptpn2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] } ] }, { "uniprot_ac": "A0A9J7FG56", "gene_name": "Cdc25c", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] } ] }, { "uniprot_ac": "A0A9J7FIV0", "gene_name": "LOC100763249", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] } ] }, { "uniprot_ac": "A0A9J7FKB3", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] } ] }, { "uniprot_ac": "A0A9J7FMB0", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] } ] }, { "uniprot_ac": "A0A9J7FWJ6", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FWX7", "gene_name": "LOC103158664", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] } ] }, { "uniprot_ac": "A0A9J7FYL8", "gene_name": "Ptpn11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] } ] }, { "uniprot_ac": "A0A9J7G003", "gene_name": "Ptprs", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G003" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G003" } ] } ] }, { "uniprot_ac": "A0A9J7G168", "gene_name": "LOC100762307", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ] } ] }, { "uniprot_ac": "A0A9J7G1A0", "gene_name": "Ptpn4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] } ] }, { "uniprot_ac": "A0A9J7G7K2", "gene_name": "Ptpn1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] } ] }, { "uniprot_ac": "A0A9J7G7L1", "gene_name": "Ptprj", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] } ] }, { "uniprot_ac": "A0A9J7GBQ5", "gene_name": "LOC100764354", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ5" } ] } ] }, { "uniprot_ac": "A0A9J7GE78", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] } ] }, { "uniprot_ac": "A0A9J7GNR2", "gene_name": "Ptpn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNR2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNR2" } ] } ] }, { "uniprot_ac": "A0A9J7GQC8", "gene_name": "LOC100757114", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GQC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQC8" } ] } ] }, { "uniprot_ac": "A0A9J7GQG9", "gene_name": "Ptprd", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] } ] }, { "uniprot_ac": "A0A9J7GX92", "gene_name": "Ptpre", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX92" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX92" } ] } ] }, { "uniprot_ac": "A0A9J7GZK0", "gene_name": "Ptprc", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZK0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZK0" } ] } ] }, { "uniprot_ac": "A0A9J7H152", "gene_name": "Ptprt", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H152" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7H152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H152" } ] } ] }, { "uniprot_ac": "A0A9J7H7L7", "gene_name": "Ptprh", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H7L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7L7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7H7L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7L7" } ] } ] }, { "uniprot_ac": "A0A9J7HBK7", "gene_name": "Ptpn22", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7HBK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7HBK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ] } ] }, { "uniprot_ac": "A0A9J7J766", "gene_name": "Ptpn20", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7J766", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J766" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7J766", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J766" } ] } ] }, { "uniprot_ac": "A0A9J7JC04", "gene_name": "Eya3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JC04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC04" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JC04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC04" } ] } ] }, { "uniprot_ac": "A0A9J7JC62", "gene_name": "Tns2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC62" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC62" } ] } ] }, { "uniprot_ac": "A0A9J7JD11", "gene_name": "Ptprm", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JD11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD11" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JD11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD11" } ] } ] }, { "uniprot_ac": "A0A9J7JTT7", "gene_name": "Ptpra", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JTT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTT7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JTT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTT7" } ] } ] }, { "uniprot_ac": "A0A9J7JU39", "gene_name": "Eya4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JU39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU39" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JU39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU39" } ] } ] }, { "uniprot_ac": "A0A9J7KAX8", "gene_name": "Eya2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7KAX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAX8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7KAX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAX8" } ] } ] }, { "uniprot_ac": "A0A9J7KDA7", "gene_name": "Ptprb", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7KDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7KDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ] } ] }, { "uniprot_ac": "A0A9J7KDM0", "gene_name": "LOC100769324", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7KDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7KDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ] } ] }, { "uniprot_ac": "G3GRD1", "gene_name": "Dusp10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] } ] }, { "uniprot_ac": "G3GWQ6", "gene_name": "Dusp29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. 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"glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 669, "start_aa": "Thr", "end_pos": 669, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr669", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBR9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBR9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBR9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBR9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752832", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752832", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "guanylate cyclase activity", "id": "GO:0004383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004383", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBR9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBR9" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBR9", 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"MEQASPTRKIPSNVITCRAAIVWTANARLSIEEVKVDPPKAGEVKIKIISAGVCGTDXEGKNKVPLPAILGLEGAGIVESVGQGVTTIKPGDKVLMFPLPECRECIYCLHPKGNFCKKEDILSSTGLMLDGTSRFTCRGKKIYHLYGTSTFTEYTVVDEIAVAKIDDATPMDKVCVTSCEVLTGFGAVFNTAQVTPGSTCVFFGLGGISSAIVMGCKASGASRIIRVDINEQKFPRARALGITDCLNPNRLKKSVDEVVMKMTGIGVDFAFEAIGLIETMVEALKSWNVSYGVYVIMGEAPSGSQFSFDPMVLLPGRTLKSSVMGVKDPRRGTFVEGDPHPRIGETTNFGCKSKRWLTLGRRFPIGRGCGGGGRPLPARPQPRGAAPGGQAWVAAPPGCYQDISWSRGREFLLGAAKYKRTQLGTTQTQAQFIRRIQTDRQDETRQKTRQRIRTTLTSQTWMADLGTEVPHRARVRGRGAPSPRSAPALGPSARRAGLGRGPAWVNRDEIPKLVSDYVENKINTDALITHKLPFEKNQGSIQIVTRGKLLLKMLPSGLHSRHSDLKSAKETDWSSA", "length": 576, "header": "tr|A0A9J7HBZ6-1|A0A9J7HBZ6_CRIGR Isoform 1 of LOW QUALITY PROTEIN: alcohol dehydrogenase 1-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC118237968 PE=4 SV=1 CANONICAL=A0A9J7HBZ6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HBZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBZ6/entry#A0A9J7HBZ6-1", "sequence": { "sequence": "MEQASPTRKIPSNVITCRAAIVWTANARLSIEEVKVDPPKAGEVKIKIISAGVCGTDXEGKNKVPLPAILGLEGAGIVESVGQGVTTIKPGDKVLMFPLPECRECIYCLHPKGNFCKKEDILSSTGLMLDGTSRFTCRGKKIYHLYGTSTFTEYTVVDEIAVAKIDDATPMDKVCVTSCEVLTGFGAVFNTAQVTPGSTCVFFGLGGISSAIVMGCKASGASRIIRVDINEQKFPRARALGITDCLNPNRLKKSVDEVVMKMTGIGVDFAFEAIGLIETMVEALKSWNVSYGVYVIMGEAPSGSQFSFDPMVLLPGRTLKSSVMGVKDPRRGTFVEGDPHPRIGETTNFGCKSKRWLTLGRRFPIGRGCGGGGRPLPARPQPRGAAPGGQAWVAAPPGCYQDISWSRGREFLLGAAKYKRTQLGTTQTQAQFIRRIQTDRQDETRQKTRQRIRTTLTSQTWMADLGTEVPHRARVRGRGAPSPRSAPALGPSARRAGLGRGPAWVNRDEIPKLVSDYVENKINTDALITHKLPFEKNQGSIQIVTRGKLLLKMLPSGLHSRHSDLKSAKETDWSSA", "length": 576, "header": "tr|A0A9J7HBZ6-1|A0A9J7HBZ6_CRIGR Isoform 1 of LOW QUALITY PROTEIN: alcohol dehydrogenase 1-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC118237968 PE=4 SV=1 CANONICAL=A0A9J7HBZ6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 195, "start_aa": "Thr", "end_pos": 195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr195", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBZ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBZ6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBZ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBZ6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:118237968", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118237968", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBZ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBZ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBZ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBZ6" } ], "pmid": "" }, { "name": "all-trans-retinol dehydrogenase (NAD+) activity", "id": "GO:0004745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004745", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBZ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBZ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "retinol metabolic process", "id": "GO:0042572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042572", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBZ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBZ6" } ], "pmid": "" }, { "name": "retinoic acid metabolic process", "id": "GO:0042573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042573", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBZ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBZ6" }, { "id": "PF00107", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00107" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alcohol dehydrogenase-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 207, "end_pos": 326, "start_aa": "Gly", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7HBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBZ6" }, { "id": "PF08240", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alcohol dehydrogenase-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 166, "start_aa": "Ala", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 195 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 288, "end_pos": 290 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HBZ7-1", "uniprot_ac": "A0A9J7HBZ7", "uniprot_id": "A0A9J7HBZ7_CRIGR", "mass": { "chemical_mass": 49697.0, "monoisotopic_mass": 49697.0 }, "refseq": { "ac": "XP_035309431", "name": "zinc finger protein 431-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309431" }, "gene_names": [ { "name": "LOC113837925", "type": "recommended", "evidence": [ { "id": "A0A9J7HBZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBZ7" } ] }, { "name": "LOC113837925", "type": "synonym", "evidence": [ { "id": "XP_035309431", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309431" } ] } ], "protein_names": [ { "name": "Zinc finger protein 431-like", "type": "synonym", "evidence": [ { "id": "A0A9J7HBZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBZ7/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 431-like", "type": "synonym", "evidence": [ { "id": "XP_035309431", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309431" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309431" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBZ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBZ7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113837925", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBZ7", "locus": {} } ], "crossref": [ { "id": "A0A9J7HBZ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HBZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113837925", "url": "https://www.ncbi.nlm.nih.gov/gene/113837925", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113837925", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837925", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HBZ7", "url": "https://www.orthodb.org/?gene=A0A9J7HBZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19818:SF157", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19818:SF157", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309431", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HBZ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYMVSLYSCRNHMPNPITYDDVHIDFTWKEWTLLDTSQKNLYKDVMLETYKNLTDIGYSWEDNTTEEQCTSSKRHERHEGSQTGEKRSAYTQCLKSFAHNSHLQRHKTTHTGEKPYECNQCGKAFARNSHLQIHKRTHTGEKPYECNQCGKAFSQHSHLQTHKRTHSGEKPYECIQCGKAFPHQSTLKMHKRTHTGEKPYGCNQCGQAFARHSHLKMHKRRHTGEKPYECSQCGKAFSHQNTLQMHKRIHTGEKPYECNQCGKAFIYNSVLRVHKRSHTGEKPYECNQCGKVFSHHSNLQMHKRTHTGEKPYECNQCGKAFARNSHLQMHKRVHTGEKPYECNQCGKAFARNSHLQMHKRVHTGEKPYECNQCGKAFAHNSHLQIHKRTHTGEKPYECIQCGKAFVQHISLQMHEGTHKEQKHYE", "length": 425, "header": "tr|A0A9J7HBZ7-1|A0A9J7HBZ7_CRIGR Isoform 1 of Zinc finger protein 431-like OS=Cricetulus griseus OX=10029 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"https://www.ncbi.nlm.nih.gov/protein/XP_035309140" }, "gene_names": [ { "name": "Adamts3", "type": "recommended", "evidence": [ { "id": "A0A9J7HC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC02" } ] }, { "name": "Adamts3", "type": "synonym", "evidence": [ { "id": "XP_035309140", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309140" } ] } ], "protein_names": [ { "name": "A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_035309140", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309140" }, { "id": "A0A9J7HC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC02/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309140", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309140" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC02", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC02" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Adamts3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC02", "locus": {} } ], "crossref": [ { "id": "A0A9J7HC02", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HC02", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04273", "database": "CDD", "categories": [ "Protein Classification" ] 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"Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758325", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758325", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HC02", "url": "https://www.orthodb.org/?gene=A0A9J7HC02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723:SF158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723:SF158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05986", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05986", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19236", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19236", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309140", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309140", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HC02", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC02-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HEA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HEA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVQIDLPIKRYREYELVTPVSTNLKGHYISHILSANHKKRSPRDVSSNSEQLFFNVTAFGRDFHLRLKPNTHFIAPGAVVEWHETSPRPGNITDPGNSHQHGSASEKIWRSEPLQTSCAYVGDIMDIPGTSVAISNCDGLAGMIRSDTEEYFIEPLERGKQMEEETGRIHIVYKRAAVEQTPRGVSKDVYYRESDVEGLDDLGTVYSNIGQQLNETMRRRRHSGENDYNIEVLLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWACQQQKPDPNHAEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFEHDWPKLPELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAAGKWCYKGHCMWKNANQQKQDGNWGSWTKFGSCSRTCGTGVRFRTRQCNNPTPINGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNSHFEYQNSKHHWLPHEHPDSKKRCHLYCQSKETGDVAYMKQLVHDGTRCSYKDPYSICVRGECVKVGCDKEIGSNKVEDKCGVCGGDNSHCRTVKGTFTRTPRKLGKTRGVFVLPKGARNISLAETRETKNVLAIKNQATGHYILNGKGEEAKSRTFIDLGVEWDYSIEDDIETLHTDGPLHDPVIVLIIPQENDTRSSLTYKYIIHEDSVPTINSNNVIQEELDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEVNKKPKPIRRMCNIQECTHPLWAAEEWEHCSKSCGSSGYQLRTVRCLQPLHDGTNRSVHSKYCLGERPESRRPCNRVPCPAQWKTGPWNECSVTCGEGTEVRQVLCRTGDHCDGEKPESIRPCQLPPCNDEPCLGDKSIFCQMEVLARYCSIPGYNKLCCESCSKRSGTLPPSYLHEAAEIHSDAIFGPSDLPRSLVMPTPFLPYYSGTHAEKKSLSSTSSMANPNAYAAFRASSRPSANFPQEKIQQAGRKMLVSIPPSSSIKTDHFRSASPVAAAPSPDASDSIGASTQTRTPKKDGKNISKRHPVRSATSER", 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"length": 1175, "header": "tr|A0A9J7HC02-1|A0A9J7HC02_CRIGR Isoform 1 of A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X4 OS=Cricetulus griseus OX=10029 GN=Adamts3 PE=4 SV=1 CANONICAL=A0A9J7HC02-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HEA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC02/entry#A0A9J7HEA6-1", "sequence": { "sequence": "MVQIDLPIKRYREYELVTPVSTNLKGHYISHILSANHKKRSPRDVSSNSEQLFFNVTAFGRDFHLRLKPNTHFIAPGAVVEWHETSPRPGNITDPGNSHQHGSASEKIWRSEPLQTSCAYVGDIMDIPGTSVAISNCDGLAGMIRSDTEEYFIEPLERGKQMEEETGRIHIVYKRAAVEQTPRGVSKDVYYRESDVEGLDDLGTVYSNIGQQLNETMRRRRHSGENDYNIEVLLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWACQQQKPDPNHAEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFEHDWPKLPELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAAGKWCYKGHCMWKNANQQKQDGNWGSWTKFGSCSRTCGTGVRFRTRQCNNPTPINGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNSHFEYQNSKHHWLPHEHPDSKKRCHLYCQSKETGDVAYMKQLVHDGTRCSYKDPYSICVRGECVKVGCDKEIGSNKVEDKCGVCGGDNSHCRTVKGTFTRTPRKLGYLKMFDIPPGARHVLVQEDEASPHVLAIKNQATGHYILNGKGEEAKSRTFIDLGVEWDYSIEDDIETLHTDGPLHDPVIVLIIPQENDTRSSLTYKYIIHEDSVPTINSNNVIQEELDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEVNKKPKPIRRMCNIQECTHPLWAAEEWEHCSKSCGSSGYQLRTVRCLQPLHDGTNRSVHSKYCLGERPESRRPCNRVPCPAQWKTGPWNECSVTCGEGTEVRQVLCRTGDHCDGEKPESIRPCQLPPCNDEPCLGDKSIFCQMEVLARYCSIPGYNKLCCESCSKRSGTLPPSYLHEAAEIHSDAIFGPSDLPRSLVMPTPFLPYYSGTHAEKKSLSSTSSMANPNAYAAFRASSRPSANFPQEKIQQAGRKMLVSIPPSSSIKTDHFRSASPVAAAPSPDASDSIGASTQTRTPKKDGKNISKRHPVRSATSER", "length": 1174, "header": "tr|A0A9J7HEA6-1|A0A9J7HEA6_CRIGR Computationally mapped isoform of A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X3 OS=Cricetulus griseus OX=10029 GN=Adamts3 PE=4 SV=1 CANONICAL=A0A9J7HC02-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC02", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC02" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC02", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC02" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758325", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758325", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC02", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC02" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC02", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC02" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC02", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC02" } ], "pmid": "" }, { "name": "collagen fibril organization", "id": "GO:0030199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC02", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC02" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC02", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1161, "end_pos": 1163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" }, { "start_pos": 713, "end_pos": 715, "annotation": "n_glycosylation_sequon" }, { "start_pos": 787, "end_pos": 789, "annotation": "n_glycosylation_sequon" }, { "start_pos": 915, "end_pos": 917, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC02" }, { "id": "PS50900", "database": "PROSITE", "url": 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This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309509" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC46" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113838583", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC46", "locus": {} } ], "crossref": [ { "id": "A0A9J7HC46", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HC46", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04138", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04138", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113838583", "url": "https://www.ncbi.nlm.nih.gov/gene/113838583", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113838583", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838583", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HC83", "url": "https://www.orthodb.org/?gene=A0A9J7HC83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309509", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HC46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC46-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC83", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC83-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEYKLMVVGADGVGKSALTIQLIQNHFVDVYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAMNNTKSFEAIHHYREQIKRAKDSEDMPMVLVGNKCDLPSRTVDTNQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGRVKNKKCIVM", "length": 189, "header": "tr|A0A9J7HC46-1|A0A9J7HC46_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113838583 PE=3 SV=1 CANONICAL=A0A9J7HC46-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HC46-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC46/entry#A0A9J7HC46-1", "sequence": { "sequence": "MSEYKLMVVGADGVGKSALTIQLIQNHFVDVYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAMNNTKSFEAIHHYREQIKRAKDSEDMPMVLVGNKCDLPSRTVDTNQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGRVKNKKCIVM", "length": 189, "header": "tr|A0A9J7HC46-1|A0A9J7HC46_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113838583 PE=3 SV=1 CANONICAL=A0A9J7HC46-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HC83-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC46/entry#A0A9J7HC83-1", "sequence": { "sequence": "MSEYKLMVVGADGVGKSALTIQLIQNHFVDVYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAMNNTKSFEAIHHYREQIKRAKDSEDMPMVLVGNKCDLPSRTVDTNQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRQNHKEKMSKDGKKKKKKSKTKCIIM", "length": 189, "header": "tr|A0A9J7HC83-1|A0A9J7HC83_CRIGR Computationally mapped isoform of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113838583 PE=3 SV=1 CANONICAL=A0A9J7HC46-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HCH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC46/entry#A0A9J7HCH7-1", "sequence": { "sequence": "MSEYKLMVVGADGVGKSALTIQLIQNHFVDVYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAMNNTKSFEAIHHYREQIKRAKDSEDMPMVLVGNKCDLPSRTVDTNQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKINGKKKKKKSKTKCIIM", "length": 187, "header": "tr|A0A9J7HCH7-1|A0A9J7HCH7_CRIGR Computationally mapped isoform of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113838583 PE=3 SV=1 CANONICAL=A0A9J7HC46-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "cge:113838583", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838583", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC46" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC46" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC46" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRJ8-1", "G3GY22-1", "G3H2D6-1", "G3HID1-1", "A0A9J7FY79-1", "G3IBI0-1", "G3HIM4-1", "G3HLW5-1", "G3I0B0-1", "G3H8L7-1", "G3IMU0-1", "G3HQ45-1", "G3HX83-1", "G3H515-1", "G3HRK4-1", "G3HWS3-1", "G3I185-1", "G3I2E9-1", "G3IHJ9-1", "G3I5Q9-1", "G3H3P1-1", "G3HGA7-1", "A0A9J7K0Q7-1", "G3I8B8-1", "A0A9J7FPY4-1", "A0A9J7JNI7-1", "A0A9J7JTM0-1", "G3HXK0-1", "G3I1T6-1", "A0A8C2M8V3-1", "G3HAT4-1", "G3HBU1-1", "A0A8C2MG78-1", "A0A9J7JFJ5-1", "A0A061I5F7-1", "A0A9J7GMX4-1", "G3H3X0-1", "A0A8C2MG41-1", "A0A8C2MJU2-1", "A0A8C2MKJ3-1", "A0A8C2QMP3-1", "A0A9J7F720-1", "A0A061IFE4-1", "A0A061HZZ7-1", "A0A8C2M6H7-1", "A0A8C2M9W6-1", "A0A9J7H2L4-1", "A0A8C2MH13-1", "A0A8C2MMV7-1", "A0A8C2MPE2-1", "A0A8C2LL65-1", "A0A3L7HXE9-1", "A0A8C2LGZ8-1", "A0A8C2LIB5-1", "A0A8C2LNU7-1", "A0A9J7JYH7-1", "A0A8C2LV21-1", "A0A9J7GDV9-1", "A0A8C2QEY0-1", "A0A9J7FVQ6-1", "A0A9J7K0X9-1", "A0A9J7J7P8-1", "A0A8C2M2X0-1", "A0A8C2MAV7-1", "A0A8C2MQL3-1", "A0A3L7HA69-1", "A0A8C2LLE7-1", "A0A061HWM0-1", "A0A061I5K5-1", "A0A061IH58-1", "A0A061INW8-1", "A0A3L7GXQ2-1", "A0A9J7GN19-1", "A0A3L7HQ44-1", "A0A3L7IA35-1", "A0A3L7IMK5-1", "A0A8C2LIE2-1", "A0A9J7GAZ9-1", "A0A9J7HCG9-1", "A0A9J7HC46-1", "A0A9J7HC79-1", "A0A9J7HCE0-1", "A0A9J7JRE1-1", "A0A9J7GJ78-1", "A0A9J7GKH5-1", "A0A9J7GL76-1", "A0A9J7GLC6-1", "A0A9J7GRC9-1", "A0A9J7GM12-1", "A0A9J7GM74-1", "A0A9J7GP64-1", "A0A9J7GPV5-1", "A0A9J7GQI1-1", "A0A9J7GR82-1", "A0A9J7JY44-1", "A0A9J7JTP9-1", "A0A9J7HGR2-1", "A0A9J7JZZ6-1", "A0A9J7K3I9-1", "A0A9J7K4X6-1", "A0A9J7HD72-1", "A0A9J7KEX2-1", "A0A9J7KFX8-1", "A0A9J7KEY0-1", "A0A9J7KF02-1", "A0A9J7KF14-1", "A0A9J7HFH8-1", "A0A9J7HEY0-1", "A0A9J7KG38-1", "A0A9J7HCJ6-1", "A0A9J7HCM3-1", "A0A9J7HCS9-1", "A0A9J7HD53-1", "A0A9J7HD81-1", "A0A9J7HFN4-1", "A0A9J7HCM7-1", "A0A9J7HCP3-1", "A0A9J7HD44-1", "A0A9J7HFL5-1", "A0A9J7HEX1-1", "A0A9J7HF32-1", "A0A9J7HFQ3-1", "A0A9J7GPD5-1", "A0A9J7HGT1-1", "A0A9J7HH79-1", "A0A9J7GR00-1", "P09445-1", "P62629-1", "P68361-1", "P68362-1", "P68365-1", "Q9QVY3-1", "A0A9J7F4Q2-1", "A0A9J7H7U2-1", "G3GW97-1", "A0A9J7K418-1", "A0A8C2QEV4-1", "A0A9J7FCD6-1", "A0A9J7JMD0-1", "A0A9J7K9Z1-1", "A0A9J7K3M9-1", "A0A8C2ME21-1", "A0A061I233-1", "A0A3L7H955-1", "A0A8C2MJ36-1", "A0A9J7FDQ9-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HWM0", "gene_name": "LOC113837706", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061HWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HWM0" } ] }, { 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"https://www.uniprot.org/uniprotkb/A0A061I233" } ] } ] }, { "uniprot_ac": "A0A061I5F7", "gene_name": "Rac1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061I5F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I5F7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061I5F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I5F7" } ] } ] }, { "uniprot_ac": "A0A061I5K5", "gene_name": "Rasl11a", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061I5K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I5K5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061I5K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I5K5" } ] } ] }, { "uniprot_ac": "A0A061IFE4", "gene_name": "Rab24", "activity": [ { 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"url": "https://www.uniprot.org/uniprotkb/A0A061INW8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061INW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061INW8" } ] } ] }, { "uniprot_ac": "A0A3L7GXQ2", "gene_name": "LOC113838564", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3L7GXQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GXQ2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3L7GXQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GXQ2" } ] } ] }, { "uniprot_ac": "A0A3L7H955", "gene_name": "Rab43", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3L7H955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H955" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": 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RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309525", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309525" } ] }, { "annotation": "Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. Binds to polypyrimidine-rich controlling element (PCE) of CFTR and promotes exon skipping of CFTR exon 9, thereby antagonizing TIA1 and its role in exon inclusion of CFTR exon 9. Plays a role in the splicing of pyruvate kinase PKM by binding repressively to a polypyrimidine tract flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC54", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC54#function" }, { "database": "UniProtKB", "id": "ARBA00055436", "url": "https://www.uniprot.org/uniprotkb/ARBA00055436#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC54", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC54" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100766574", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC54", "locus": {} } ], "crossref": [ { "id": "A0A9J7HC54", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HC54", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12777", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12777", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766574", "url": "https://www.ncbi.nlm.nih.gov/gene/100766574", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766574", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766574", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HC54", "url": "https://www.orthodb.org/?gene=A0A9J7HC54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309525", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309525", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HC54", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC54-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC54-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGIVPDIAVGTKRGSEELFSTCVSSGPFIMSSSTSAANGNDSKKFKGDNRNTEVPSRVIHVRSLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYLQFSNHKELKTDSSPNHARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRILVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNRFQALLQYADPVSAQHAKLSLDGQNIYKAWCSLRIDFSKLTSLYVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGLSVPNVHGALAPLAIPSAASAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVLRVKILFNNKENALVQMADGSQAQRAMSHLNGHKLHGKSLRIILSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSPTLHLSNIPPSLSEDDLKNLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGDNHHLRVSFSKSTI", "length": 529, "header": "tr|A0A9J7HC54-1|A0A9J7HC54_CRIGR Isoform 1 of Polypyrimidine tract-binding protein 1 OS=Cricetulus griseus OX=10029 GN=LOC100766574 PE=4 SV=1 CANONICAL=A0A9J7HC54-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HC54-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC54/entry#A0A9J7HC54-1", "sequence": { "sequence": "MDGIVPDIAVGTKRGSEELFSTCVSSGPFIMSSSTSAANGNDSKKFKGDNRNTEVPSRVIHVRSLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYLQFSNHKELKTDSSPNHARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRILVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNRFQALLQYADPVSAQHAKLSLDGQNIYKAWCSLRIDFSKLTSLYVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGLSVPNVHGALAPLAIPSAASAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVLRVKILFNNKENALVQMADGSQAQRAMSHLNGHKLHGKSLRIILSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSPTLHLSNIPPSLSEDDLKNLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGDNHHLRVSFSKSTI", "length": 529, "header": "tr|A0A9J7HC54-1|A0A9J7HC54_CRIGR Isoform 1 of Polypyrimidine tract-binding protein 1 OS=Cricetulus griseus OX=10029 GN=LOC100766574 PE=4 SV=1 CANONICAL=A0A9J7HC54-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:100766574", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766574", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC54", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC54" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC54", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC54" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC54", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC54" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC54", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC54" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC54", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC54" } ], "pmid": "" }, { "name": "negative regulation of mRNA metabolic process", "id": "GO:1903312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903312", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC54", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC54" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HC54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC54" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 142, "start_aa": "Arg", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A9J7HC64-1", "uniprot_ac": "A0A9J7HC64", "uniprot_id": "A0A9J7HC64_CRIGR", "mass": { "chemical_mass": 53271.0, "monoisotopic_mass": 53271.0 }, "refseq": { "ac": "XP_035307906", "name": "cytokine receptor-like factor 1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307906" }, "gene_names": [ { "name": "Crlf1", "type": "recommended", "evidence": [ { "id": "A0A9J7HC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ] }, { "name": "Crlf1", "type": "synonym", "evidence": [ { "id": "XP_035307906", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307906" } ] } ], "protein_names": [ { "name": "Cytokine receptor-like factor 1", "type": "recommended", "evidence": [ { "id": "A0A9J7HC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64/entry#names_and_taxonomy" } ] }, { "name": "Cytokine-like factor 1", "type": "synonym", "evidence": [ { "id": "A0A9J7HC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64/entry#names_and_taxonomy" } ] }, { "name": "cytokine receptor-like factor 1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_035307906", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307906" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307906", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307906" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Crlf1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64", "locus": {} } ], "crossref": [ { "id": "A0A9J7HC64", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HC64", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767254", "url": "https://www.ncbi.nlm.nih.gov/gene/100767254", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767254", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767254", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HC64", "url": "https://www.orthodb.org/?gene=A0A9J7HC64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23036:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23036:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307906", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307906", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MHR1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MHR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MHR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MHR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F6D0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F6D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6D0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F849", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F849", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F849-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F849-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F8B5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F8B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8B5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9Z3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAM4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBX2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC64-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HE31", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HE31-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBI8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAGRPGPAAQSARRPPRPLSSLWSPLLLCVLGVPRGGSGTHTAVISPQDPTLLIGSSLQATCSIHGDTPGATAEGLYWTLNGRRLPSELSHLLNTSTLALALANLNGSRQQSGDNLVCHARDGSILAGSCLYVGLPPEKPFNISCWSRNMKDLTCRWTPGAHGDTFLHTNYSLKYKLRWYGQDNTCEDYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDVLDVVTRPAPPPVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSDLVWEAAVPPACAPCRLHSDTTAPLSLERPGPGGGVCEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSFRLYDQWRAWMQKSHKTRNQLFFPSTGRGDPALGQTGHGERSCRINYKGQAILLQLAELEVCPN", "length": 486, "header": "tr|A0A9J7HC64-1|A0A9J7HC64_CRIGR Isoform 1 of Cytokine receptor-like factor 1 OS=Cricetulus griseus OX=10029 GN=Crlf1 PE=3 SV=1 CANONICAL=A0A9J7HC64-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MHR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64/entry#A0A8C2MHR1-1", "sequence": { "sequence": "MPAGRPGPAAQSARRPPRPLSSLWSPLLLCVLGVPRGGSGTHTAVISPQDPTLLIGSSLQATCSIHGDTPGATAEGLYWTLNGRRLPSELSHLLNTSTLALALANLNGSRQQSGDNLVCHARDGSILAGSCLYVGLPPEKPFNISCWSRNMKDLTCRWTPGAHGDTFLHTNYSLKYKLRWYGQDNTCEDYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDVLDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSERPGPGGGVCEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSFRLYDQWRAWMQKSHKTRNQDEGILPSGRRGTARGPAG", "length": 425, "header": "tr|A0A8C2MHR1-1|A0A9J7HC64_CRIGR Computationally mapped isoform of Cytokine receptor-like factor 1 OS=Cricetulus griseus OX=10029 GN=Crlf1 PE=3 SV=1 CANONICAL=A0A9J7HC64-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F6D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64/entry#A0A9J7F6D0-1", "sequence": { "sequence": "MPAGRPGPAAQSARRPPRPLSSLWSPLLLCVLGVPRGGSGTHTAVISPQDPTLLIGSSLQATCSIHGDTPGATAEGLYWTLNGRRLPSELSHLLNTSTLALALANLNGSRQQSGDNLVCHARDGSILAGSCLYVGLPPEKPFNISCWSRNMKDLTCRWTPGAHGDTFLHTNYSLKYKLRWYGQDNTCEDYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDVLDVVTRPAPPPVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSERPGPGGGVCEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSFRLYDQWRAWMQKSHKTRNQLFFPSTGRGDPALGQTGHGERSCRINYKGQAILLQLAELEVCPN", "length": 442, "header": "tr|A0A9J7F6D0-1|A0A9J7HC64_CRIGR Computationally mapped isoform of Cytokine receptor-like factor 1 OS=Cricetulus griseus OX=10029 GN=Crlf1 PE=3 SV=1 CANONICAL=A0A9J7HC64-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F849-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64/entry#A0A9J7F849-1", "sequence": { "sequence": "MPAGRPGPAAQSARRPPRPLSSLWSPLLLCVLGVPRGGSGTHTAVISPQDPTLLIGSSLQATCSIHGDTPGATAEGLYWTLNGRRLPSELSHLLNTSTLALALANLNGSRQQSGDNLVCHARDGSILAGSCLYVGLPPEKPFNISCWSRNMKDLTCRWTPGAHGDTFLHTNYSLKYKLRWYGQDNTCEDYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDVLDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSERPGPGGGVCEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSFRLYDQWRAWMQKSHKTRNQLFFPSTGRGDPALGQTGHGERSCRINYKGQAILLQLAELEVCPN", "length": 451, "header": "tr|A0A9J7F849-1|A0A9J7HC64_CRIGR Computationally mapped isoform of Cytokine receptor-like factor 1 OS=Cricetulus griseus OX=10029 GN=Crlf1 PE=3 SV=1 CANONICAL=A0A9J7HC64-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F8B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64/entry#A0A9J7F8B5-1", "sequence": { "sequence": "MPAGRPGPAAQSARRPPRPLSSLWSPLLLCVLGVPRGGSGTHTAVISPQDPTLLIGSSLQATCSIHGDTPGATAEGLYWTLNGRRLPSELSHLLNTSTLALALANLNGSRQQSGDNLVCHARDGSILAGSCLYVGLPPEKPFNISCWSRNMKDLTCRWTPGAHGDTFLHTNYSLKYKLRWYGQDNTCEDYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDVLDVVTRPAPPPVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSERPGPGGGVCEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSFRLYDQWRAWMQKSHKTRNQLFFPSTGRGDPALGQTGHGERSCRINYKGQAILLQLAELEVCPN", "length": 459, "header": "tr|A0A9J7F8B5-1|A0A9J7HC64_CRIGR Computationally mapped isoform of Cytokine receptor-like factor 1 OS=Cricetulus griseus OX=10029 GN=Crlf1 PE=3 SV=1 CANONICAL=A0A9J7HC64-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64/entry#A0A9J7H9Z3-1", "sequence": { "sequence": "MPAGRPGPAAQSARRPPRPLSSLWSPLLLCVLGVPRGGSGTHTAVISPQDPTLLIGSSLQATCSIHGDTPGATAEGLYWTLNGRRLPSELSHLLNTSTLALALANLNGSRQQSGDNLVCHARDGSILAGSCLYVGLPPEKPFNISCWSRNMKDLTCRWTPGAHGDTFLHTNYSLKYKLRWYGQDNTCEDYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDVLDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSDLVWEAAVPPACAPCRLHSDTTAPLSLERPGPGGGVCEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSFRLYDQWRAWMQKSHKTRNQLFFPSTGRGDPALGQTGHGERSCRINYKGQAILLQLAELEVCPN", "length": 478, "header": "tr|A0A9J7H9Z3-1|A0A9J7HC64_CRIGR Computationally mapped isoform of Cytokine receptor-like factor 1 OS=Cricetulus griseus OX=10029 GN=Crlf1 PE=3 SV=1 CANONICAL=A0A9J7HC64-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64/entry#A0A9J7HAM4-1", "sequence": { "sequence": "MPAGRPGPAAQSARRPPRPLSSLWSPLLLCVLGVPRGGSGTHTAVISPQDPTLLIGSSLQATCSIHGDTPGATAEGLYWTLNGRRLPSELSHLLNTSTLALALANLNGSRQQSGDNLVCHARDGSILAGSCLYVGLPPEKPFNISCWSRNMKDLTCRWTPGAHGDTFLHTNYSLKYKLRWYGQDNTCEDYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDVLDVVTRPAPPPVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSDLVWEAAVPPACAPCRLHSDTTAPLSLERPGPGGGVCEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSFRLYDQWRAWMQKSHKTRNQHRTRGSCPRADGARREVLPDKL", "length": 464, "header": "tr|A0A9J7HAM4-1|A0A9J7HC64_CRIGR Computationally mapped isoform of Cytokine receptor-like factor 1 OS=Cricetulus griseus OX=10029 GN=Crlf1 PE=3 SV=1 CANONICAL=A0A9J7HC64-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HBX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64/entry#A0A9J7HBX2-1", "sequence": { "sequence": "MPAGRPGPAAQSARRPPRPLSSLWSPLLLCVLGVPRGGSGTHTAVISPQDPTLLIGSSLQATCSIHGDTPGATAEGLYWTLNGRRLPSELSHLLNTSTLALALANLNGSRQQSGDNLVCHARDGSILAGSCLYVGLPPEKPFNISCWSRNMKDLTCRWTPGAHGDTFLHTNYSLKYKLRWYGQDNTCEDYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDVLDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSERPGPGGGVCEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSFRLYDQWRAWMQKSHKTRNQHRTRGSCPRADGARREVLPDKL", "length": 429, "header": "tr|A0A9J7HBX2-1|A0A9J7HC64_CRIGR Computationally mapped isoform of Cytokine receptor-like factor 1 OS=Cricetulus griseus OX=10029 GN=Crlf1 PE=3 SV=1 CANONICAL=A0A9J7HC64-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HC64-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64/entry#A0A9J7HC64-1", "sequence": { "sequence": "MPAGRPGPAAQSARRPPRPLSSLWSPLLLCVLGVPRGGSGTHTAVISPQDPTLLIGSSLQATCSIHGDTPGATAEGLYWTLNGRRLPSELSHLLNTSTLALALANLNGSRQQSGDNLVCHARDGSILAGSCLYVGLPPEKPFNISCWSRNMKDLTCRWTPGAHGDTFLHTNYSLKYKLRWYGQDNTCEDYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDVLDVVTRPAPPPVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSDLVWEAAVPPACAPCRLHSDTTAPLSLERPGPGGGVCEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSFRLYDQWRAWMQKSHKTRNQLFFPSTGRGDPALGQTGHGERSCRINYKGQAILLQLAELEVCPN", "length": 486, "header": "tr|A0A9J7HC64-1|A0A9J7HC64_CRIGR Isoform 1 of Cytokine receptor-like factor 1 OS=Cricetulus griseus OX=10029 GN=Crlf1 PE=3 SV=1 CANONICAL=A0A9J7HC64-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HE31-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64/entry#A0A9J7HE31-1", "sequence": { "sequence": "MPAGRPGPAAQSARRPPRPLSSLWSPLLLCVLGVPRGGSGTHTAVISPQDPTLLIGSSLQATCSIHGDTPGATAEGLYWTLNGRRLPSELSHLLNTSTLALALANLNGSRQQSGDNLVCHARDGSILAGSCLYVGLPPEKPFNISCWSRNMKDLTCRWTPGAHGDTFLHTNYSLKYKLRWYGQDNTCEDYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDVLDVVTRPAPPPVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSDLVWEAAVPPACAPCRLHSDTTAPLSLERPGPGGGVCEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSFRLYDQWRAWMQKSHKTRNQLFFPSTGRGDPALGQTGHGERSCRINYKGQAILLQLAELEVCPN", "length": 469, "header": "tr|A0A9J7HE31-1|A0A9J7HE31_CRIGR Computationally mapped isoform of Cytokine receptor-like factor 1 isoform X6 OS=Cricetulus griseus OX=10029 GN=Crlf1 PE=3 SV=1 CANONICAL=A0A9J7HC64-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64/entry#A0A9J7KBI8-1", "sequence": { "sequence": "MPAGRPGPAAQSARRPPRPLSSLWSPLLLCVLGVPRGGSGTHTAVISPQDPTLLIGSSLQATCSIHGDTPGATAEGLYWTLNGRRLPSELSHLLNTSTLALALANLNGSRQQSGDNLVCHARDGSILAGSCLYVGLPPEKPFNISCWSRNMKDLTCRWTPGAHGDTFLHTNYSLKYKLRWYGQDNTCEDYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDVLDVVTRPAPPPVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSDLVWEAAVPPACAPCRLHSDTTAPLSLERPGPGGGVCEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSFRLYDQWRAWMQKSHKTRNQDEGILPSGRRGTARGPAG", "length": 460, "header": "tr|A0A9J7KBI8-1|A0A9J7HC64_CRIGR Computationally mapped isoform of Cytokine receptor-like factor 1 OS=Cricetulus griseus OX=10029 GN=Crlf1 PE=3 SV=1 CANONICAL=A0A9J7HC64-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MHR1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MHR1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MHR1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MHR1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767254", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767254", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ], "pmid": "" }, { "name": "CRLF-CLCF1 complex", "id": "GO:0097058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097058", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ], "pmid": "" }, { "name": "protein secretion", "id": "GO:0009306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009306", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ], "pmid": "" }, { "name": "ureteric bud development", "id": "GO:0001657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001657", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ], "pmid": "" }, { "name": "negative regulation of motor neuron apoptotic process", "id": "GO:2000672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000672", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via STAT", "id": "GO:0097696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097696", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ], "pmid": "" }, { "name": "cytokine binding", "id": "GO:0019955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019955", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ], "pmid": "" }, { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ], "pmid": "" }, { "name": "ciliary neurotrophic factor receptor binding", "id": "GO:0005127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005127", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ], "pmid": "" }, { "name": "protein carrier chaperone", "id": "GO:0140597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140597", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC64" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 140, "end_pos": 235, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 143, "end_pos": 145 }, { "start_pos": 171, "end_pos": 173 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 420, "end_pos": 422 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J511-1", "uniprot_ac": "A0A9J7J511", "uniprot_id": "A0A9J7J511_CRIGR", "mass": { "chemical_mass": 85902.0, "monoisotopic_mass": 85902.0 }, "refseq": { "ac": "XP_027249024", "name": "tripartite motif-containing protein 46 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249024" }, "gene_names": [ { "name": "Trim46", "type": "recommended", "evidence": [ { "id": "A0A9J7J511", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" } ] }, { "name": "Trim46", "type": "synonym", "evidence": [ { "id": "XP_027249024", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249024" } ] } ], "protein_names": [ { "name": "Tripartite motif-containing protein 46", "type": "recommended", "evidence": [ { "id": "A0A9J7J511", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511/entry#names_and_taxonomy" } ] }, { "name": "tripartite motif-containing protein 46 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027249024", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249024" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027249024", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249024" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J511", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Trim46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511", "locus": {} } ], "crossref": [ { "id": "A0A9J7J511", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J511", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12895", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12895", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16757", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16757", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19786", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19786", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19849", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19849", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757214", "url": "https://www.ncbi.nlm.nih.gov/gene/100757214", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757214", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757214", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7J511", "url": "https://www.orthodb.org/?gene=A0A9J7J511", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18568", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18568", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027249024", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249024", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2ML74", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2ML74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2U5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2U5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J511", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J511-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J9T5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9T5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J9T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9T5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J9U6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9U6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J9U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9U6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATGARLSQRRCQPCSPPPLPSPSLPVPPSFVSAAPLTGMAAKRGTKTSMKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQTIIFPCPACQGDVELGERGLSGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLAYILGNQDTVQTQICELEETIRHTEVSGQQAKEEVSQLVRGLGAMLEEKRASLLQAIEECQQERLSRLSAQIHEHQSLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHCQLDVGREMKLLTELNFLRVPEAPVIDTQRTFAYDQIFLCWRLPPHSPPAWHYTVEFRRTDVPAQPGPARWQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDGRWGASRERLAISKDQRAVRSIPGLPLLLAAERLLTGCHLSVDVVLGDVAVTQGRSYWACAVDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEALPPFAFLTIGMGKILLGSGASSNAGLTGRDGPAAGCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLECPLDCSGPVCPAFCFIGGGAVQLQEPVGTKPERKVTIGGFAKLD", "length": 785, "header": "tr|A0A9J7J511-1|A0A9J7J511_CRIGR Isoform 1 of Tripartite motif-containing protein 46 OS=Cricetulus griseus OX=10029 GN=Trim46 PE=3 SV=1 CANONICAL=A0A9J7J511-1" }, "isoforms": [ { "isoform_ac": "A0A8C2ML74-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511/entry#A0A8C2ML74-1", "sequence": { "sequence": "MAEGEDMQTLTSIMDALVRISTSMKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQTIIFPCPACQGDVELGERGLSGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLAYILGNQDTVQTQICELEETIRHTEVSGQQAKEEVSQLVRGLGAMLEEKRASLLQAIEECQQERLSRLSAQIHEHQSLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHCQLDVGREMKLLTELNFLRVPEAPVIDTQRTFAYDQIFLCWRLPPHSPPAWHYTVEFRRTDVPAQPGPARWQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDGRWGASRERLAISKDQRAVRSIPGLPLLLAAERLLTGCHLSVDVVLGDVAVTQGRSYWACAVDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEALPPFAFLTIGMGKILLGSGASSNAGLTGRDGPAAGCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLECPLDCSGPVCPAFCFIGGGAVQLQEPVGTKPERKVTIGGFAKLD", "length": 759, "header": "tr|A0A8C2ML74-1|A0A9J7J511_CRIGR Computationally mapped isoform of Tripartite motif-containing protein 46 OS=Cricetulus griseus OX=10029 GN=Trim46 PE=3 SV=1 CANONICAL=A0A9J7J511-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F2U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511/entry#A0A9J7F2U5-1", "sequence": { "sequence": "MATGARLSQRRCQPCSPPPLPSPSLPVPPSFVSAAPLTGMAAKRGTKTSMKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQTIIFPCPACQGDVELGERGLSGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLAYILGNQDTVQTQICELEETIRHTEVSGQQAKEEVSQLVRGLGAMLEEKRASLLQAIEECQQERLSRLSAQIHEHQSLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHCQLDVGREMKLLTELNFLRVPEAPVIDTQRTFAYDQIFLCWRLPPHSPPAWHYTVEFRRTDVPAQPGPARWQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPGTTQTADMTAVPKMLR", "length": 571, "header": "tr|A0A9J7F2U5-1|A0A9J7J511_CRIGR Computationally mapped isoform of Tripartite motif-containing protein 46 OS=Cricetulus griseus OX=10029 GN=Trim46 PE=3 SV=1 CANONICAL=A0A9J7J511-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J511-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511/entry#A0A9J7J511-1", "sequence": { "sequence": "MATGARLSQRRCQPCSPPPLPSPSLPVPPSFVSAAPLTGMAAKRGTKTSMKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQTIIFPCPACQGDVELGERGLSGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLAYILGNQDTVQTQICELEETIRHTEVSGQQAKEEVSQLVRGLGAMLEEKRASLLQAIEECQQERLSRLSAQIHEHQSLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHCQLDVGREMKLLTELNFLRVPEAPVIDTQRTFAYDQIFLCWRLPPHSPPAWHYTVEFRRTDVPAQPGPARWQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDGRWGASRERLAISKDQRAVRSIPGLPLLLAAERLLTGCHLSVDVVLGDVAVTQGRSYWACAVDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEALPPFAFLTIGMGKILLGSGASSNAGLTGRDGPAAGCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLECPLDCSGPVCPAFCFIGGGAVQLQEPVGTKPERKVTIGGFAKLD", "length": 785, "header": "tr|A0A9J7J511-1|A0A9J7J511_CRIGR Isoform 1 of Tripartite motif-containing protein 46 OS=Cricetulus griseus OX=10029 GN=Trim46 PE=3 SV=1 CANONICAL=A0A9J7J511-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J9T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511/entry#A0A9J7J9T5-1", "sequence": { "sequence": "MAEGEDMQTLTSIMDALVRISTSMKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQTIIFPCPACQGDVELGERGLSGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLAYILGNQDTVQTQICELEETIRHTEVSGQQAKEEVSQLVRGLGAMLEEKRASLLQAIEECQQERLSRLSAQIHEHQSLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHCQLDVGREMKLLTELNFLRVPEAPVIDTQRTFAYDQIFLCWRLPPHSPPAWHYTVEFRRTDVPAQPGPARWQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPGTTQTADMTAVPKMLR", "length": 545, "header": "tr|A0A9J7J9T5-1|A0A9J7J9T5_CRIGR Computationally mapped isoform of Tripartite motif-containing protein 46 isoform X5 OS=Cricetulus griseus OX=10029 GN=Trim46 PE=4 SV=1 CANONICAL=A0A9J7J511-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J9U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511/entry#A0A9J7J9U6-1", "sequence": { "sequence": "MKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQTIIFPCPACQGDVELGERGLSGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLAYILGNQDTVQTQICELEETIRHTEVSGQQAKEEVSQLVRGLGAMLEEKRASLLQAIEECQQERLSRLSAQIHEHQSLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHCQLDVGREMKLLTELNFLRVPEAPVIDTQRTFAYDQIFLCWRLPPHSPPAWHYTVEFRRTDVPAQPGPARWQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDGRWGASRERLAISKDQRAVRSIPGLPLLLAAERLLTGCHLSVDVVLGDVAVTQGRSYWACAVDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEALPPFAFLTIGMGKILLGSGASSNAGLTGRDGPAAGCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLECPLDCSGPVCPAFCFIGGGAVQLQEPVGTKPERKVTIGGFAKLD", "length": 736, "header": "tr|A0A9J7J9U6-1|A0A9J7J9U6_CRIGR Computationally mapped isoform of Tripartite motif-containing protein 46 OS=Cricetulus griseus OX=10029 GN=Trim46 PE=3 SV=1 CANONICAL=A0A9J7J511-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 109, "start_aa": "Thr", "end_pos": 109, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr109", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2ML74", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML74" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2ML74", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML74" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757214", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757214", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J511", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J511", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" } ], "pmid": "" }, { "name": "axon initial segment", "id": "GO:0043194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043194", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J511", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" } ], "pmid": "" }, { "name": "proximal neuron projection", "id": "GO:1990769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990769", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J511", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" } ], "pmid": "" }, { "name": "main axon", "id": "GO:0044304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044304", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J511", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J511", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J511", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J511", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" } ], "pmid": "" }, { "name": "anterograde synaptic vesicle transport", "id": "GO:0048490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048490", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J511", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J511", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J511", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J511", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 248, "end_pos": 289, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7J511", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 539, "end_pos": 773, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7J511", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" }, { "id": "PS51262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "COS", "eco_id": "ECO_0000259", "start_pos": 396, "end_pos": 453, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7J511", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J511" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 455, "end_pos": 554, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 109 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 176, "end_pos": 178 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HC62-1", "uniprot_ac": "A0A9J7HC62", "uniprot_id": "A0A9J7HC62_CRIGR", "mass": { "chemical_mass": 70307.0, "monoisotopic_mass": 70307.0 }, "refseq": { "ac": "XP_035307426", "name": "potassium voltage-gated channel subfamily C member 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307426" }, "gene_names": [ { "name": "Kcnc2", "type": "recommended", "evidence": [ { "id": "A0A9J7HC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62" } ] }, { "name": "Kcnc2", "type": "synonym", "evidence": [ { "id": "XP_035307426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307426" } ] } ], "protein_names": [ { "name": "Potassium voltage-gated channel subfamily C member 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7HC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62/entry#names_and_taxonomy" } ] }, { "name": "potassium voltage-gated channel subfamily C member 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035307426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307426" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307426", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307426" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Kcnc2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62", "locus": {} } ], "crossref": [ { "id": "A0A9J7HC62", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HC62", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18415", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18415", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759610", "url": "https://www.ncbi.nlm.nih.gov/gene/100759610", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759610", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759610", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HC62", "url": "https://www.orthodb.org/?gene=A0A9J7HC62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537:SF172", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537:SF172", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307426", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307426", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MYX5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MYX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H957", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H957", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H957-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H957-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9V7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9V7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC62-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKIENNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPQGDCLTAAGDKLQPLPPPLSPPPRPPPLSPVPSSCFEGGAGNCSSHGGNGSDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSAVLQYEIETDPALTYVEGVCVVWFTFEFLVRIIFSPNKLEFVKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPLASSPTFCKTELNMACNSTQSDTCLGKENRLLEHNRSVLSGDDSTGSEPPLSPPERLPIRRSSTRDKNRRGETCFLLTTGDYTCTSDGGIRKGYEKSRSLNNIAGLAGNALRLSPVTSPYNSPCPLRRSRSPIPSIL", "length": 638, "header": "tr|A0A9J7HC62-1|A0A9J7HC62_CRIGR Isoform 1 of Potassium voltage-gated channel subfamily C member 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Kcnc2 PE=4 SV=1 CANONICAL=A0A9J7HC62-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MYX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62/entry#A0A8C2MYX5-1", "sequence": { "sequence": "MGKIENNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPQGDCLTAAGDKLQPLPPPLSPPPRPPPLSPVPSSCFEGGAGNCSSHGGNGSDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSAVLQYEIETDPALTYVEGVCVVWFTFEFLVRIIFSPNKLEFVKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPLASSPTFCKTELNMACNSTQSDTCLGKENRLLEHNRSVLSGDDSTGSEPPLSPPERLPIRRSSTRDKNRRGETCFLLTTGDYTCTSDGGIRKASTLEPMESTTQSRGDTRQEAHWDCVHLLNFGCPTGSSFPAL", "length": 635, "header": "tr|A0A8C2MYX5-1|A0A9J7HC62_CRIGR Computationally mapped isoform of Potassium voltage-gated channel subfamily C member 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Kcnc2 PE=4 SV=1 CANONICAL=A0A9J7HC62-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H957-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62/entry#A0A9J7H957-1", "sequence": { "sequence": "MGKIENNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPQGDCLTAAGDKLQPLPPPLSPPPRPPPLSPVPSSCFEGGAGNCSSHGGNGSDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSAVLQYEIETDPALTYVEGVCVVWFTFEFLVRIIFSPNKLEFVKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPLASSPTFCKTELNMACNSTQSDTCLGKENRLLEHNRSVLSGDDSTGSEPPLSPPERLPIRRSSTRDKNRRGETCFLLTTGDYTCTSDGGIRKDNCKEVVITGYTQAEARSLT", "length": 613, "header": "tr|A0A9J7H957-1|A0A9J7HC62_CRIGR Computationally mapped isoform of Potassium voltage-gated channel subfamily C member 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Kcnc2 PE=4 SV=1 CANONICAL=A0A9J7HC62-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62/entry#A0A9J7H9V7-1", "sequence": { "sequence": "MGKIENNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPQGDCLTAAGDKLQPLPPPLSPPPRPPPLSPVPSSCFEGGAGNCSSHGGNGSDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSAVLQYEIETDPALTYVEGVCVVWFTFEFLVRIIFSPNKLEFVKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPLASSPTFCKTELNMACNSTQSDTCLGKENRLLEHNRSDNCKEVVITGYTQAEARSLT", "length": 558, "header": "tr|A0A9J7H9V7-1|A0A9J7HC62_CRIGR Computationally mapped isoform of Potassium voltage-gated channel subfamily C member 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Kcnc2 PE=4 SV=1 CANONICAL=A0A9J7HC62-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HC62-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62/entry#A0A9J7HC62-1", "sequence": { "sequence": "MGKIENNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPQGDCLTAAGDKLQPLPPPLSPPPRPPPLSPVPSSCFEGGAGNCSSHGGNGSDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSAVLQYEIETDPALTYVEGVCVVWFTFEFLVRIIFSPNKLEFVKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPLASSPTFCKTELNMACNSTQSDTCLGKENRLLEHNRSVLSGDDSTGSEPPLSPPERLPIRRSSTRDKNRRGETCFLLTTGDYTCTSDGGIRKGYEKSRSLNNIAGLAGNALRLSPVTSPYNSPCPLRRSRSPIPSIL", "length": 638, "header": "tr|A0A9J7HC62-1|A0A9J7HC62_CRIGR Isoform 1 of Potassium voltage-gated channel subfamily C member 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Kcnc2 PE=4 SV=1 CANONICAL=A0A9J7HC62-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HDA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62/entry#A0A9J7HDA7-1", "sequence": { "sequence": "MGKIENNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPQGDCLTAAGDKLQPLPPPLSPPPRPPPLSPVPSSCFEGGAGNCSSHGGNGSDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSAVLQYEIETDPALTYVEGVCVVWFTFEFLVRIIFSPNKLEFVKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPLASSPTFCKTELNMACNSTQSDTCLGKENRLLEHNRSGYEKSRSLNNIAGLAGNALRLSPVTSPYNSPCPLRRSRSPIPSIL", "length": 583, "header": "tr|A0A9J7HDA7-1|A0A9J7HDA7_CRIGR Computationally mapped isoform of Potassium voltage-gated channel subfamily C member 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Kcnc2 PE=4 SV=1 CANONICAL=A0A9J7HC62-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYX5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYX5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYX5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYX5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759610", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759610", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "delayed rectifier potassium channel activity", "id": "GO:0005251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005251", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62" } ], "pmid": "" }, { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62" } ], "pmid": "" }, { "name": "neuronal cell body membrane", "id": "GO:0032809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032809", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62" } ], "pmid": "" }, { "name": "dendrite membrane", "id": "GO:0032590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032590", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62" } ], "pmid": "" }, { "name": "action potential", "id": "GO:0001508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62" } ], "pmid": "" }, { "name": "membrane hyperpolarization", "id": "GO:0060081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060081", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62" } ], "pmid": "" }, { "name": "regulation of action potential firing rate", "id": "GO:0099605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099605", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC62" }, { "id": "SM00225", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 159, "start_aa": "Glu", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 259, "end_pos": 261 }, { "start_pos": 266, "end_pos": 268 }, { "start_pos": 518, "end_pos": 520 }, { "start_pos": 536, "end_pos": 538 }, { "start_pos": 84, "end_pos": 86 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J7J6-1", "uniprot_ac": "A0A9J7J7J6", "uniprot_id": "A0A9J7J7J6_CRIGR", "mass": { "chemical_mass": 57268.0, "monoisotopic_mass": 57268.0 }, "refseq": { "ac": "XP_027243227", "name": "runt-related transcription factor 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243227" }, "gene_names": [ { "name": "Runx2", "type": "recommended", "evidence": [ { "id": "A0A9J7J7J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7J6" } ] }, { "name": "Runx2", "type": "synonym", "evidence": [ { "id": "XP_027243227", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243227" } ] } ], "protein_names": [ { "name": "Runt-related transcription factor 2 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7J7J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7J6/entry#names_and_taxonomy" } ] }, { "name": "runt-related transcription factor 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027243227", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243227" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027243227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243227" } ] }, { "annotation": "Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EUE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUE8#function" }, { "database": "UniProtKB", "id": "PIRNR009374", "url": "https://www.uniprot.org/uniprotkb/PIRNR009374#function" }, { "database": "UniProtKB", "id": "A0A9J7EYY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYY1#function" }, { "database": "UniProtKB", "id": "A0A9J7EYY5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYY5#function" }, { "database": "UniProtKB", "id": "A0A9J7F045", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F045#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7J6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7J6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Runx2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7J6", "locus": {} } ], "crossref": [ { "id": "A0A9J7J7J6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J7J6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100753922", "url": "https://www.ncbi.nlm.nih.gov/gene/100753922", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013711", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013711", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016554", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016554", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753922", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753922", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7EYY5", "url": "https://www.orthodb.org/?gene=A0A9J7EYY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J7J6", "url": "https://www.orthodb.org/?gene=A0A9J7J7J6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11950", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11950", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11950:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11950:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08504", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08504", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027243227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243227", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7EUE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EUE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EWL3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EWL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EWL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EWL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EYY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EYY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EYY5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EYY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F045", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F045", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F045-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F045-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7J6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7J6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7J6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQQQQQQEAAARRRRAAAQRRAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDSEPSTLDSQSSTTLFLSSEEPGPSTAALPSPSSSCEPQAFSPSSTMLPSLLPPLSTASTAPGPCIPRRGGLYTIVTSSPEAAPHLVDWLPNCPSATSPGVRGKDHERPQPVLAPAPALERGHIQHPGSARDDHAEGPRTSPPPCAPEVTIATLEANVGDILVELRTMNGHLDIIAKALTKLASSLVPQPQPEAPDTN", "length": 529, "header": "tr|A0A9J7J7J6-1|A0A9J7J7J6_CRIGR Isoform 1 of Runt-related transcription factor 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Runx2 PE=4 SV=1 CANONICAL=A0A9J7J7J6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7EUE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7J6/entry#A0A9J7EUE8-1", "sequence": { "sequence": "MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQQQQQQEAAARRRRAAAQRRAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRNPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSASYQFPMVPGGDRSPSRMLPACTTTSNGSTLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY", "length": 432, "header": "tr|A0A9J7EUE8-1|A0A9J7J7J6_CRIGR Computationally mapped isoform of Runt-related transcription factor 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Runx2 PE=4 SV=1 CANONICAL=A0A9J7J7J6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EWL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7J6/entry#A0A9J7EWL3-1", "sequence": { "sequence": "MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQQQQQQEAAARRRRAAAQRRAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRNPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDSEPSTLDSQSSTTLFLSSEEPGPSTAALPSPSSSCEPQAFSPSSTMLPSLLPPLSTASTAPGPCIPRRGGLYTIVTSSPEAAPHLVDWLPNCPSATSPGVRGKDHERPQPVLAPAPALERGHIQHPGSARDDHAEGPRTSPPPCAPEVTIATLEANVGDILVELRTMNGHLDIIAKALTKLASSLVPQPQPEAPDTN", "length": 471, "header": "tr|A0A9J7EWL3-1|A0A9J7J7J6_CRIGR Computationally mapped isoform of Runt-related transcription factor 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Runx2 PE=4 SV=1 CANONICAL=A0A9J7J7J6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EYY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7J6/entry#A0A9J7EYY1-1", "sequence": { "sequence": "MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQQQQQQEAAARRRRAAAQRRAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSASYQFPMVPGGDRSPSRMLPACTTTSNGSTLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY", "length": 490, "header": "tr|A0A9J7EYY1-1|A0A9J7J7J6_CRIGR Computationally mapped isoform of Runt-related transcription factor 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Runx2 PE=4 SV=1 CANONICAL=A0A9J7J7J6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EYY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7J6/entry#A0A9J7EYY5-1", "sequence": { "sequence": "MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQQQQQQEAAARRRRAAAQRRAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSSLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSASYQFPMVPGGDRSPSRMLPACTTTSNGSTLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY", "length": 512, "header": "tr|A0A9J7EYY5-1|A0A9J7J7J6_CRIGR Computationally mapped isoform of Runt-related transcription factor 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Runx2 PE=4 SV=1 CANONICAL=A0A9J7J7J6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F045-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7J6/entry#A0A9J7F045-1", "sequence": { "sequence": "MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQQQQQQEAAARRRRAAAQRRAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRNPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSSLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSASYQFPMVPGGDRSPSRMLPACTTTSNGSTLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY", "length": 454, "header": "tr|A0A9J7F045-1|A0A9J7J7J6_CRIGR Computationally mapped isoform of Runt-related transcription factor 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Runx2 PE=4 SV=1 CANONICAL=A0A9J7J7J6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J7J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7J6/entry#A0A9J7J7J6-1", "sequence": { "sequence": "MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQQQQQQEAAARRRRAAAQRRAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDSEPSTLDSQSSTTLFLSSEEPGPSTAALPSPSSSCEPQAFSPSSTMLPSLLPPLSTASTAPGPCIPRRGGLYTIVTSSPEAAPHLVDWLPNCPSATSPGVRGKDHERPQPVLAPAPALERGHIQHPGSARDDHAEGPRTSPPPCAPEVTIATLEANVGDILVELRTMNGHLDIIAKALTKLASSLVPQPQPEAPDTN", "length": 529, "header": "tr|A0A9J7J7J6-1|A0A9J7J7J6_CRIGR Isoform 1 of Runt-related transcription factor 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Runx2 PE=4 SV=1 CANONICAL=A0A9J7J7J6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EUE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUE8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027249725", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249725" } ] }, { "annotation": "Molecular adapter that recruits protein complexes required for cilium assembly and function to the cilium basal body. At the exit of mitosis, localizes to the basal body and ciliary base of the forming primary cilium where it recruits and activates RAB8A to direct vesicle-mediated transport of proteins to the cilium. Also recruits the BBSome, a complex involved in cilium biogenesis, by bridging it to PCM1 at the centriolar satellites of the cilium. It is also required for the recruitment to the cilium basal body of the intraflagellar transport (IFT) machinery as well as the ciliary appendage proteins CEP164 and NINEIN. Functions as a regulator of Hedgehog signaling both through its role in cilium assembly but also probably through its ability to retain GLI3 within the cytoplasm. It is involved in spermatogenesis through its role in organization of the basal body and assembly of the sperm flagellum. 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"id": "A0A8C2N3C5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N3C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F3U2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F3U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3U2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F761", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F761", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F761-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F761-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F7S8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F7S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F7S8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F879", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F879", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F879-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F879-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J5H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JAB0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JAB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JAB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JAB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JBT7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JBT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KF38", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KF38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KF38-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KF38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFQKHIYYPLANSPEGPDASAAGAAPMASVPPGAASGPLPFFQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKLIRLAQLTIEYLMHSQEFLTSQLNLVEERLRLSLIDYEQSKQLLSKQAGEIKLLKDECKRRKKMLSTQQLMIEAKASYYQEEVCQEAMLQTPGLLPQADGKTHCRHLNLSLSFQCHFCDKAFMNQAFLQSHIQRRHSAESHLEYNTKAQTDRLQKEIDMLKEQLQLTRSQLESAQYAHAVRFSKEHEMQKTKEDDFLKLFERWKEEEKEKLLDEMEKVKEMFMKEFKELTSKNSALEYQLLEIQKSNMQIKSNIGTLKDINECKEDHPPCPQDFQNMLQLLDSQASKWSDRFQVLNEEHSKEKGQLLSHIEKLRSSMMEDLSADNVFYKRRVEELGQKVQEQNELILSQRQQIREFTSKPCNNVGELKGNPLTWQAMDSKPANPAAPMGAPATQTLDGASSLPMVHEQGFSSHVLEPIEELSSEEEKGRENEQKLNKKTHFRKTLRGNPSSKGLRTNLEKELGKKLRSFGIDADIHGIPCEILNKSLKAMQLARHDLAKQMPNIQQIRESLEHQLICKIEEKVSLTSDRHNDPPMIISAAEEAPKATQLPPQSRPLVRQRAVFTDKVAVPKLKKNTKEIPLLKKFSATKTPPFSSEEEPEEEDLIQAYVSSDLMTLQPCKNSMSNLRKSSVRSDTDWTEGSEMEDSDVSPKPSGTSIKIQTEDVESMVLHEGSGSNLVTGMNIAETLVKREELHEFKCAEVDNDDWDVSSLEEEKSLEKRMEQREPLPVKRDLSSSQLPRAWGPVNPREFKEEDFICVTVPPRAGPEPSVSLNQHLEYQDDRSSSPLWASELCGLLPCVRLGTYCHTVTGQRGCNIAIVKISLLRIKTVFERRLPYTELRGCSRTRTLRPSENILDSS", "length": 962, "header": "tr|A0A9J7J5H1-1|A0A9J7J5H1_CRIGR Isoform 1 of Zinc finger protein DZIP1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dzip1 PE=3 SV=1 CANONICAL=A0A9J7J5H1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N3C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1/entry#A0A8C2N3C5-1", "sequence": { "sequence": "MPFQKHIYYPLANSPEGPDASAAGAAPMASVPPGAASGPLPFFQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKLIRLAQLTIEYLMHSQEFLTSQLNLVEERLRLSLIDYEQSKQLLSKQAGEIKLLKDECKRRKKMLSTQQLMIEAKASYYQCHFCDKAFMNQAFLQSHIQRRHSAESHLEYNTKAQTDRLQKEIDMLKEQLQLTRSQLESAQYAHAVRFSKEHEMQKTKEDDFLKLFERWKEEEKEKLLDEMEKVKEMFMKEFKELTSKNSALEYQLLEIQKSNMQIKSNIGTLKDINECKEDHPPCPQDFQNMLQLLDSQASKWSDRFQVLNEEHSKEKGQLLSHIEKLRSSMMEDLSADNVFYKRRVEELGQKVQEQNELILSQRQQIREFTSKPCNNVGELKGNPLTWQAMDSKPANPAAPMGAPATQTLDGASSLPMVHEQGFSSHVLEPIEELSSEEEKGRENEQKLNKKTHFRKTLRGNPSSKGLRTNLEKELGKKLRSFGIDADIHGIPCEILNKSLKAMQLARHDLAKQMPNIQQIRESLEHQLICKIEEKVSLTSDRHNDPPMIISAAEEAPKATQLPPQSRPLVRQRAVFTDKVAVPKLKKNTKEIPLLKKFSATKTPPFSSEEEPEEEDLIQAYVSSDLMTLQPCKNSMSNLRKSSVRSDTDWTEGSEMEDSDVSPKPSGTSIKIQTEDVESMVLHEGSGSNLVTGMNIAETLVKREELHEFKCAEVDNDDWDVSSLEEEKSLEKRMEQREPLPVKRDLSSSQLPRAWGPVNPREFKEEGLQEKEASTLKSSLVTVTDWSDVLDV", "length": 849, "header": "tr|A0A8C2N3C5-1|A0A9J7J5H1_CRIGR Computationally mapped isoform of Zinc finger protein DZIP1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dzip1 PE=3 SV=1 CANONICAL=A0A9J7J5H1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F2Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1/entry#A0A9J7F2Y4-1", "sequence": { "sequence": "MPFQKHIYYPLANSPEGPDASAAGAAPMASVPPGAASGPLPFFQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKLIRLAQLTIEYLMHSQEFLTSQLNLVEERLRLSLIDYEQSKQLLSKQAGEIKLLKDECKRRKKMLSTQQLMIEAKASYYQEEVCQEAMLQTPGLLPQADGKTHCRHLNLSLSFQCHFCDKAFMNQAFLQSHIQRRHSAESHLEYNTKAQTDRLQKEIDMLKEQLQLTRSQLESAQYAHAVRFSKEHEMQKTKEDDFLKLFERWKEEEKEKLLDEMEKVKEMFMKEFKELTSKNSALEYQLLEIQKSNMQIKSNIGTLKDINECKEDHPPCPQDFQNMLQLLDSQASKWSDRFQVLNEEHSKEKGQLLSHIEKLRSSMMEDLSADNVFYKRRVEELGQKVQEQNELILSQRQQIREFTSKPCNNVGELKGNPLTWQAMDSKPANPAAPMGAPATQTLDGASSLPMVHEQGFSSHVLEPIEELSSEEEKGRENEQKLNKKTHFRKTLRGNPSSKGLRTNLEKELGKKLRSFGIDADIHGIPCEILNKSLKAMQLARHDLAKQMPNIQQIRESLEHQLICKIEEKVSLTSDRHNDPPMIISAAEEAPKATQLPPQSRPLVRQRAVFTDKVAVPKLKKNTKEIPLLKKFSATKTPPFSSEEEPEEEDLIQAYVSSDLMTLQPCKNSMSNLRKSSVRSDTDWTEGSEMEDSDVSPKPSGTSIKIQTEDVESMVLHEGSGSNLVTGMNIAETLVKREELHEFKCAEVDNDDWDVSSLEEEKSLEKRMEQREPLPVKRDLSSSQLPRAWGPVNPREFKEEGLQEKEASTLKSSLVTVTDWSDVLDV", "length": 883, "header": "tr|A0A9J7F2Y4-1|A0A9J7J5H1_CRIGR Computationally mapped isoform of Zinc finger protein DZIP1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dzip1 PE=3 SV=1 CANONICAL=A0A9J7J5H1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F3U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1/entry#A0A9J7F3U2-1", "sequence": { "sequence": "MPFQKHIYYPLANSPEGPDASAAGAAPMASVPPGAASGPLPFFQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKLIRLAQLTIEYLMHSQEFLTSQLNLVEERLRLSLIDYEQSKQLLSKQAGEIKLLKDECKRRKKMLSTQQLMIEAKASYYQCHFCDKAFMNQAFLQSHIQRRHSAESHLEYNTKAQTDRLQKEIDMLKEQLQLTRSQLESAQYAHAVRFSKEHEMQKTKEDDFLKLFERWKEEEKEKLLDEMEKVKEMFMKEFKELTSKNSALEYQLLEIQKSNMQIKSNIGTLKDINECKEDHPPCPQDFQNMLQLLDSQASKWSDRFQVLNEEHSKEKGQLLSHIEKLRSSMMEDLSADNVFYKRRVEELGQKVQEQNELILSQRQQIREFTSKPCNNVGELKGNPLTWQAMDSKPANPAAPMGAPATQTLDGASSLPMVHEQGFSSHVLEPIEELSSEEEKGRENEQKLNKKTHFRKTLRGNPSSKGLRTNLEKELGKKLRSFGIDADIHGIPCEILNKSLKAMQLARHDLAKQMPNIQQIRESLEHQLICKIEEKVSLTSDRHNDPPMIISAAEEAPKATQLPPQSRPLVRQRAVFTDKVAVPKLKKNTKEIPLLKKFSATKTPPFSSEEEPEEEDLIQAYVSSDLMTLQPCKNSMSNLRKSSVRSDTDWTEGSEMEDSDVSPKPSGTSIKIQTEDVESMVLHEGSGSNLVTGMNIAETLVKREELHEFKCAEVDNDDWDVSSLEEEKSLEKRMEQREPLPVKRDLSSSQLPRAWGPVNPREFKEEDFICVTVPPRAGPEPSVSLNQHLEYQDDRSSSPLWASELCGLLPCVRLGTYCHTVTGQRGCNIAIVKISLLRIKTVFERRLPYTELRGCSRTRTLRPSENILDSS", "length": 928, "header": "tr|A0A9J7F3U2-1|A0A9J7J5H1_CRIGR Computationally mapped isoform of Zinc finger protein DZIP1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dzip1 PE=3 SV=1 CANONICAL=A0A9J7J5H1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F761-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1/entry#A0A9J7F761-1", "sequence": { "sequence": "MPFQKHIYYPLANSPEGPDASAAGAAPMASVPPGAASGPLPFFQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKLIRLAQLTIEYLMHSQEFLTSQLNLVEERLRLSLIDYEQSKQLLSKQAGEIKLLKDECKRRKKMLSTQQLMIEAKASYYQEEVCQEAMLQTPGLLPQADGKTHCRHLNLSLSFQCHFCDKAFMNQAFLQSHIQRRHSAESHLEYNTKAQTDRLQKEIDMLKEQLQLTRSQLESAQYAHAVRFSKEHEMQKTKEDDFLKLFERWKEEEKEKLLDEMEKVKEMFMKEFKELTSKNSALEYQLLEIQKSNMQIKSNIGTLKDINECKEDHPPCPQDFQNMLQLLDSQASKWSDRFQVLNEEHSKEKGQLLSHIEKLRSSMMEDLSADNVFYKRRVEELGQKVQEQNELILSQRQQIREFTSKPCNNVGELKGNPLTWQAMDSKPANPAAPKQGFSSHVLEPIEELSSEEEKGRENEQKLNKKTHFRKTLRGNPSSKGLRTNLEKELGKKLRSFGIDADIHGIPCEILNKSLKAMQLARHDLAKQMPNIQQIRESLEHQLICKIEEKVSLTSDRHNDPPMIISAAEEAPKATQLPPQSRPLVRQRAVFTDKVAVPKLKKNTKEIPLLKKFSATKTPPFSSEEEPEEEDLIQAYVSSDLMTLQPCKNSMSNLRKSSVRSDTDWTEGSEMEDSDVSPKPSGTSIKIQTEDVESMVLHEGSGSNLVTGMNIAETLVKREELHEFKCAEVDNDDWDVSSLEEEKSLEKRMEQREPLPVKRDLSSSQLPRAWGPVNPREFKEEGLQEKEASTLKSSLVTVTDWSDVLDV", "length": 864, "header": "tr|A0A9J7F761-1|A0A9J7J5H1_CRIGR Computationally mapped isoform of Zinc finger protein DZIP1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dzip1 PE=3 SV=1 CANONICAL=A0A9J7J5H1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F7S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1/entry#A0A9J7F7S8-1", "sequence": { "sequence": "MPFQKHIYYPLANSPEGPDASAAGAAPMASVPPGAASGPLPFFQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKLIRLAQLTIEYLMHSQEFLTSQLNLVEERLRLSLIDYEQSKQLLSKQAGEIKLLKDECKRRKKMLSTQQLMIEAKASYYQEEVCQEAMLQTPGLLPQADGKTHCRHLNLSLSFQCHFCDKAFMNQAFLQSHIQRRHSAESHLEYNTKAQTDRLQKEIDMLKEQLQLTRSQLESAQYAHAVRFSKEHEMQKTKEDDFLKLFERWKEEEKEKLLDEMEKVKEMFMKEFKELTSKNSALEYQLLEIQKSNMQIKSNIGTLKDINECKEDHPPCPQDFQNMLQLLDSQASKWSDRFQVLNEEHSKEKGQLLSHIEKLRSSMMEDLSADNVFYKRRVEELGQKVQEQNELILSQRQQIREFTSKPCNNVGELKGNPLTWQAMDSKPANPAAPMGAPATQTLDGASSLPMVHEQGFSSHVLEPIEELSSEEEKGRENEQKLNKKTHFRKTLRGNPSSKGLRTNLEKELGKKLRSFGIDADIHGIPCEILNKSLKAMQLARHDLAKQMPNIQQIRESLEHQLICKIEEKVSLTSDRHNDPPMIISAAEEAPKATQLPPQSRPLVRQRAVFTDKVAVPKLKKNTKEIPLLKKFSATKTPPFSSEEEPEEEDLIQAYVSSDLMTLQPCKNSMSNLRKSSVRSDTDWTEGSEMEDSDVSPKPSGTSIKIQTEDVESMVLHEGSGSNLVTGMNIAETLVKREELHEFKCAEVDNDDWDVSSLEEEKSLEKRMEQREPLPVKRDLSSSQLPRAWGPVNPREFKEEDFICVTVPPRAGPEPSVSLNQHLEYQDDRTSRKGSKHSEK", "length": 897, "header": "tr|A0A9J7F7S8-1|A0A9J7J5H1_CRIGR Computationally mapped isoform of Zinc finger protein DZIP1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dzip1 PE=3 SV=1 CANONICAL=A0A9J7J5H1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F879-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1/entry#A0A9J7F879-1", "sequence": { "sequence": "MPFQKHIYYPLANSPEGPDASAAGAAPMASVPPGAASGPLPFFQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKLIRLAQLTIEYLMHSQEFLTSQLNLVEERLRLSLIDYEQSKQLLSKQAGEIKLLKDECKRRKKMLSTQQLMIEAKASYYQEEVCQEAMLQTPGLLPQADGKTHCRHLNLSLSFQCHFCDKAFMNQAFLQSHIQRRHSAESHLEYNTKAQTDRLQKEIDMLKEQLQLTRSQLESAQYAHAVRFSKEHEMQKTKEDDFLKLFERWKEEEKEKLLDEMEKVKEMFMKEFKELTSKNSALEYQLLEIQKSNMQIKSNIGTLKDINECKEDHPPCPQDFQNMLQLLDSQASKWSDRFQVLNEEHSKEKGQLLSHIEKLRSSMMEDLSADNVFYKRRVEELGQKVQEQNELILSQRQQIREFTSKPCNNVGELKGNPLTWQAMDSKPANPAAPMGAPATQTLDGASSLPMVHEQGFSSHVLEPIEELSSEEEKGRENEQKLNKKTHFRKTLRGNPSSKGLRTNLEKELGKKLRSFGIDADIHGIPCEILNKSLKAMQLARHDLAKQMPNIQQIRESLEHQLICKIEEKVSLTSDRHNDPPMIISAAEEAPKATQLPPQSRPLVRQRAVFTDKVAVPKLKKNTKEIPLLKKFSATKTPPFSSEEEPEEEDLIQAYVSSDLMTLQPCKNSMSNLRKSSVRSDTDWTEGSEMEDSDVSPKPSGTSIKIQTEDVESMVLHEGSGSNLVTGMNIAETLVKREELHEFKLCHVSSIGSLVLFPPSPSMSAAQPKPHREREALFL", "length": 836, "header": "tr|A0A9J7F879-1|A0A9J7J5H1_CRIGR Computationally mapped isoform of Zinc finger protein DZIP1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dzip1 PE=3 SV=1 CANONICAL=A0A9J7J5H1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HDT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1/entry#A0A9J7HDT3-1", "sequence": { "sequence": "MPFQKHIYYPLANSPEGPDASAAGAAPMASVPPGAASGPLPFFQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKLIRLAQLTIEYLMHSQEFLTSQLNLVEERLRLSLIDYEQSKQLLSKQAGEIKLLKDECKRRKKMLSTQQLMIEAKASYYQEEVCQEAMLQTPGLLPQADGKTHCRHLNLSLSFQCHFCDKAFMNQAFLQSHIQRRHSAESHLEYNTKAQTDRLQKEIDMLKEQLQLTRSQLESAQYAHAVRFSKEHEMQKTKEDDFLKLFERWKEEEKEKLLDEMEKVKEMFMKEFKELTSKNSALEYQLLEIQKSNMQIKSNIGTLKDINECKEDHPPCPQDFQNMLQLLDSQASKWSDRFQVLNEEHSKEKGQLLSHIEKLRSSMMEDLSADNVFYKRRVEELGQKVQEQNELILSQRQQIREFTSKPCNNVGELKGNPLTWQAMDSKPANPAAPMGAPATQTLDGASSLPMVHEQGFSSHVLEPIEELSSEEEKGRENEQKLNKKTHFRKTLRGNPSSKGLRTNLEKELGKKLRSFGIDADIHGIPCEILNKSLKAMQLARHDLAKQMPNIQQIRESLEHQLICKIEEKVSLTSDRHNDPPMIISAAEEAPKATQLPPQSRPLVRQRAVFTDKVAVPKLKKNTKEIPLLKKFSATNGYRWCHFLSWCVWDRCSLQDASLQLRGGAGRRGLDPGVRFFRPDDPAAV", "length": 742, "header": "tr|A0A9J7HDT3-1|A0A9J7HDT3_CRIGR Computationally mapped isoform of Cilium assembly protein DZIP1 OS=Cricetulus griseus OX=10029 GN=Dzip1 PE=3 SV=1 CANONICAL=A0A9J7J5H1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J5H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1/entry#A0A9J7J5H1-1", "sequence": { "sequence": "MPFQKHIYYPLANSPEGPDASAAGAAPMASVPPGAASGPLPFFQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKLIRLAQLTIEYLMHSQEFLTSQLNLVEERLRLSLIDYEQSKQLLSKQAGEIKLLKDECKRRKKMLSTQQLMIEAKASYYQEEVCQEAMLQTPGLLPQADGKTHCRHLNLSLSFQCHFCDKAFMNQAFLQSHIQRRHSAESHLEYNTKAQTDRLQKEIDMLKEQLQLTRSQLESAQYAHAVRFSKEHEMQKTKEDDFLKLFERWKEEEKEKLLDEMEKVKEMFMKEFKELTSKNSALEYQLLEIQKSNMQIKSNIGTLKDINECKEDHPPCPQDFQNMLQLLDSQASKWSDRFQVLNEEHSKEKGQLLSHIEKLRSSMMEDLSADNVFYKRRVEELGQKVQEQNELILSQRQQIREFTSKPCNNVGELKGNPLTWQAMDSKPANPAAPMGAPATQTLDGASSLPMVHEQGFSSHVLEPIEELSSEEEKGRENEQKLNKKTHFRKTLRGNPSSKGLRTNLEKELGKKLRSFGIDADIHGIPCEILNKSLKAMQLARHDLAKQMPNIQQIRESLEHQLICKIEEKVSLTSDRHNDPPMIISAAEEAPKATQLPPQSRPLVRQRAVFTDKVAVPKLKKNTKEIPLLKKFSATKTPPFSSEEEPEEEDLIQAYVSSDLMTLQPCKNSMSNLRKSSVRSDTDWTEGSEMEDSDVSPKPSGTSIKIQTEDVESMVLHEGSGSNLVTGMNIAETLVKREELHEFKCAEVDNDDWDVSSLEEEKSLEKRMEQREPLPVKRDLSSSQLPRAWGPVNPREFKEEDFICVTVPPRAGPEPSVSLNQHLEYQDDRSSSPLWASELCGLLPCVRLGTYCHTVTGQRGCNIAIVKISLLRIKTVFERRLPYTELRGCSRTRTLRPSENILDSS", "length": 962, "header": "tr|A0A9J7J5H1-1|A0A9J7J5H1_CRIGR Isoform 1 of Zinc finger protein DZIP1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dzip1 PE=3 SV=1 CANONICAL=A0A9J7J5H1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JAB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1/entry#A0A9J7JAB0-1", "sequence": { "sequence": "MPFQKHIYYPLANSPEGPDASAAGAAPMASVPPGAASGPLPFFQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKLIRLAQLTIEYLMHSQEFLTSQLNLVEERLRLSLIDYEQSKQLLSKQAGEIKLLKDECKRRKKMLSTQQLMIEAKASYYQEEVCQEAMLQTPGLLPQADGKTHCRHLNLSLSFQCHFCDKAFMNQAFLQSHIQRRHSAESHLEYNTKAQTDRLQKEIDMLKEQLQLTRSQLESAQYAHAVRFSKEHEMQKTKEDDFLKLFERWKEEEKEKLLDEMEKVKEMFMKEFKELTSKNSALEYQLLEIQKSNMQIKSNIGTLKDINECKEDHPPCPQDFQNMLQLLDSQASKWSDRFQVLNEEHSKEKGQLLSHIEKLRSSMMEDLSADNVFYKRRVEELGQKVQEQNELILSQRQQIREFTSKPCNNVGELKGNPLTWQAMDSKPANPAAPKQGFSSHVLEPIEELSSEEEKGRENEQKLNKKTHFRKTLRGNPSSKGLRTNLEKELGKKLRSFGIDADIHGIPCEILNKSLKAMQLARHDLAKQMPNIQQIRESLEHQLICKIEEKVSLTSDRHNDPPMIISAAEEAPKATQLPPQSRPLVRQRAVFTDKVAVPKLKKNTKEIPLLKKFSATKTPPFSSEEEPEEEDLIQAYVSSDLMTLQPCKNSMSNLRKSSVRSDTDWTEGSEMEDSDVSPKPSGTSIKIQTEDVESMVLHEGSGSNLVTGMNIAETLVKREELHEFKCAEVDNDDWDVSSLEEEKSLEKRMEQREPLPVKRDLSSSQLPRAWGPVNPREFKEEDFICVTVPPRAGPEPSVSLNQHLEYQDDRSSSPLWASELCGLLPCVRLGTYCHTVTGQRGCNIAIVKISLLRIKTVFERRLPYTELRGCSRTRTLRPSENILDSS", "length": 943, "header": "tr|A0A9J7JAB0-1|A0A9J7JAB0_CRIGR Computationally mapped isoform of Zinc finger protein DZIP1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Dzip1 PE=3 SV=1 CANONICAL=A0A9J7J5H1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JAB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1/entry#A0A9J7JAB7-1", "sequence": { "sequence": "MPFQKHIYYPLANSPEGPDASAAGAAPMASVPPGAASGPLPFFQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKLIRLAQLTIEYLMHSQEFLTSQLNLVEERLRLSLIDYEQSKQLLSKQAGEIKLLKDECKRRKKMLSTQQLMIEAKASYYQEEVCQEAMLQTPGLLPQADGKTHCRHLNLSLSFQCHFCDKAFMNQAFLQSHIQRRHSAESHLEYNTKAQTDRLQKEIDMLKEQLQLTRSQLESAQYAHAVRFSKEHEMQKTKEDDFLKLFERWKEEEKEKLLDEMEKVKEMFMKEFKELTSKNSALEYQLLEIQKSNMQIKSNIGTLKDINECKEDHPPCPQDFQNMLQLLDSQASKWSDRFQVLNEEHSKEKGQLLSHIEKLRSSMMEDLSADNVFYKRRVEELGQKVQEQNELILSQRQQIREFTSKPCNNVGELKGNPLTWQAMDSKPANPAAPMGAPATQTLDGASSLPMVHEQGFSSHVLEPIEELSSEEEKGRENEQKLNKKTHFRKTLRGNPSSKGLRTNLEKELGKKLRSFGIDADIHGIPCEILNKSLKAMQLARHDLAKQMPNIQQIRESLEHQLICKIEEKVSLTSDRHNDPPMIISAAEEAPKATQLPPQSRPLVRQRAVFTDKVAVPKLKKNTKEIPLLKKFSATKTPPFSSEEEPEEEDLIQAYVSSDLMTLQPCKNSMSNLRKSSVRSDTDWTEGSEMEDSDVSPKPSGTSIKIQTEDVESMVLHEGSGSNLVTGMNIAETLVKREELHEFKCAEVDNDDWDVSSLEEEKSLEKRMEQREPLPVKRDLSSSQLPRAWGPVNPREFKEEDFICVTVPPRAGPEPSVSLNQHLEYQDDSPVSVCSQLITQHQHVENSISRHHCERQGERSRTQALMPAAQELKGVRMDGHRPCPVRRARSVGGFSSSLPESL", "length": 959, "header": "tr|A0A9J7JAB7-1|A0A9J7JAB7_CRIGR Computationally mapped isoform of Zinc finger protein DZIP1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Dzip1 PE=3 SV=1 CANONICAL=A0A9J7J5H1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JBT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1/entry#A0A9J7JBT7-1", "sequence": { "sequence": "MPFQKHIYYPLANSPEGPDASAAGAAPMASVPPGAASGPLPFFQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKLIRLAQLTIEYLMHSQEFLTSQLNLVEERLRLSLIDYEQSKQLLSKQAGEIKLLKDECKRRKKMLSTQQLMIEAKASYYQEEVCQEAMLQTPGLLPQADGKTHCRHLNLSLSFQCHFCDKAFMNQAFLQSHIQRRHSAESHLEYNTKAQTDRLQKEIDMLKEQLQLTRSQLESAQYAHAVRFSKEHEMQKTKEDDFLKLFERWKEEEKEKLLDEMEKVKEMFMKEFKELTSKNSALEYQLLEIQKSNMQIKSNIGTLKDINECKEDHPPCPQDFQNMLQLLDSQASKWSDRFQVLNEEHSKEKGQLLSHIEKLRSSMMEDLSADNVFYKRRVEELGQKVQEQNELILSQRQQIREFTSKPCNNVGELKGNPLTWQAMDSKPANPAAPMGAPATQTLDGASSLPMVHEQGFSSHVLEPIEELSSEEEKGRENEQKLNKKTHFRKTLRGNPSSKGLRTNLEKELGKKLRSFGIDADIHGIPCEILNKSLKAMQLARHDLAKQMPNIQQIRESLEHQLICKIEEKVSLTSDRHNDPPMIISAAEEAPKATQLPPQSRPLVRQRAVFTDKVAVPKLKKNTKEIPLLKKFSATKTPPFSSEEEPEEEDLIQAYVSSDLMTLQPCKNSMSNLRKSSVRSDTDWTEGSEMEDSDVSPKPSGTSIKIQTEDVESMVLHEGSGSNLVTGMNIAETLVKREELHEFKCAEVDNDDWDVSSLEEEKSLEKRMEQREPLPVKRDLSSSQLPRAWGPVNPREFKEEGLVLNLQSL", "length": 866, "header": "tr|A0A9J7JBT7-1|A0A9J7JBT7_CRIGR Computationally mapped isoform of Zinc finger protein DZIP1 isoform X9 OS=Cricetulus griseus OX=10029 GN=Dzip1 PE=3 SV=1 CANONICAL=A0A9J7J5H1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KF38-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1/entry#A0A9J7KF38-1", "sequence": { "sequence": "MPFQKHIYYPLANSPEGPDASAAGAAPMASVPPGAASGPLPFFQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKLIRLAQLTIEYLMHSQEFLTSQLNLVEERLRLSLIDYEQSKQLLSKQAGEIKLLKDECKRRKKMLSTQQLMIEAKASYYQEEVCQEAMLQTPGLLPQADGKTHCRHLNLSLSFQCHFCDKAFMNQAFLQSHIQRRHSAESHLEYNTKAQTDRLQKEIDMLKEQLQLTRSQLESAQYAHAVRFSKEHEMQKTKEDDFLKLFERWKEEEKEKLLDEMEKVKEMFMKEFKELTSKNSALEYQLLEIQKSNMQIKSNIGTLKDINECKEDHPPCPQDFQNMLQLLDSQASKWSDRFQVLNEEHSKEKGQLLSHIEKLRSSMMEDLSADNVFYKRRVEELGQKVQEQNELILSQRQQIREFTSKPCNNVGELKGNPLTWQAMDSKPANPAAPMGAPATQTLDGASSLPMVHEQGFSSHVLEPIEELSSEEEKGRENEQKLNKKTHFRKTLRGNPSSKGLRTNLEKELGKKLRSFGIDADIHGIPCEILNKSLKAMQLARHDLAKQMPNIQQIRESLEHQLICKIEEKVSLTSDRHNDPPMIISAAEEAPKATQLPPQSRPLVRQRAVFTDKVAVPKLKKNTKEIPLLKKFSATKTPPFSSEEEPEEEDLIQAYVSSDLMTLQPCKNSMSNLRKSSVRSDTDWTEGSEMEDSDVSPKPSGTSIKIQTEDVESMVLHEGSGSNLVTGMNIAETLVKREELHEFKCAEVDNDDWDVSSLEEEKSLEKRMEQREPLPVKRDLSSSQLPRAWGPVNPREFKEEDFICVTVPPRAGPEPSVSLNQHLEYQDDSFRY", "length": 889, "header": "tr|A0A9J7KF38-1|A0A9J7J5H1_CRIGR Computationally mapped isoform of Zinc finger protein DZIP1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dzip1 PE=3 SV=1 CANONICAL=A0A9J7J5H1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F3U2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3U2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F3U2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3U2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766464", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766464", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" }, { "name": "ciliary transition fiber", "id": "GO:0097539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097539", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" }, { "name": "positive regulation of protein localization to cilium", "id": "GO:1903566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903566", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" }, { "name": "ciliary basal body organization", "id": "GO:0032053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032053", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" }, { "name": "sperm flagellum assembly", "id": "GO:0120316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120316", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" }, { "name": "protein-containing complex localization to centriolar satellite", "id": "GO:0140706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140706", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" }, { "name": "BBSome binding", "id": "GO:0062063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062063", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H1" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": 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"A0A9J7J6B3_CRIGR", "mass": { "chemical_mass": 81543.0, "monoisotopic_mass": 81543.0 }, "refseq": { "ac": "XP_003502201", "name": "protein FAM161A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502201" }, "gene_names": [ { "name": "Fam161a", "type": "recommended", "evidence": [ { "id": "A0A9J7J6B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B3" } ] }, { "name": "Fam161a", "type": "synonym", "evidence": [ { "id": "XP_003502201", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502201" } ] } ], "protein_names": [ { "name": "Protein FAM161A", "type": "recommended", "evidence": [ { "id": "A0A9J7J6B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B3/entry#names_and_taxonomy" } ] }, { "name": "protein FAM161A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003502201", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502201" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613880.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003502201.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502201", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502201" } ] }, { "annotation": "Involved in ciliogenesis.", "evidence": [ { "database": "UniProtKB", "id": "G3HDR4", "url": "https://www.uniprot.org/uniprotkb/G3HDR4#function" }, { "database": "UniProtKB", "id": "ARBA00037165", "url": "https://www.uniprot.org/uniprotkb/ARBA00037165#function" }, { "database": "UniProtKB", "id": "A0A9J7HB20", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB20#function" }, { "database": "UniProtKB", "id": "A0A9J7J6B3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B3#function" }, { "database": "UniProtKB", "id": "A0A9J7J6F9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6F9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6B3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fam161a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B3", "locus": {} } ], "crossref": [ { "id": "A0A9J7J6B3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J6B3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100770716", "url": "https://www.ncbi.nlm.nih.gov/gene/100770716", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770716", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770716", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7J6B3", "url": "https://www.orthodb.org/?gene=A0A9J7J6B3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J6F9", "url": "https://www.orthodb.org/?gene=A0A9J7J6F9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HDR4", "url": "https://www.orthodb.org/?gene=G3HDR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21501", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21501", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21501:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21501:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502201", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502201", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HB20", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HB20-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J6B3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J6B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J6F9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6F9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J6F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6F9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HDR4", "url": "https://www.uniprot.org/uniprotkb/G3HDR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HDR4-1", "url": "https://www.uniprot.org/uniprotkb/G3HDR4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLHRAARLVSGSLHLPVNPTTEPRVAQNEREDVLETLVSSALAVALEEEQKTETRPARALASGNSFPREKEDVTIQDIVDFSDVYHSNEEYFRKLRELKAAHAETMAKLEKMYQDKLNIKDVWPVITREDYSSVSSSSVSEQNCPHPGLVTSYSEPDIGQSPSLSTTSDEELPSLEREAPGESRMTAYAKELINNMWTDFSVEDYMQYDSDVQTSKKTRKKQKPWVPRVTVPVPFQMTVREQKKREAAQKARPDPQSRQKLLKRDDDDDVECKKKFRANPAPSCILQPFYEDMVRQNEERRRTSKEKSKAALLASQKPFKFIAREEEKQAIREKQLRDLFKSKRKTKWFKARPVPRSIYRSAANDKSKDDEFYRDIRTQLKARELLQNSSWPCRQGQGHFRVPRSPGKPRGRHKCKCLCPDDGNFAEKQWKESSSEPSFQKHSTLCKQCGLHEYSCDSAKRQKVLADLRADEENLKEILWPHPSPRLKSPVRSACTKPRPCRCSPPMPTLSSRGREQAIRKSLEEKKMLEEERNRILTKQKQRMKELQKLVATRVKAYDSHQGLAQMSKSRVNQLRKSEKARMKEYRRELQERNEKLQQRPMLFERVAQRNARMAAEKRYSNTLEALGLSEEFVSEKGQGGKAPESFTREELRSRTSDKESSYEEEGENEEENYFIDANSQDSCKENTEEVKEGREENSEE", "length": 703, "header": "tr|A0A9J7J6B3-1|A0A9J7J6B3_CRIGR Isoform 1 of Protein FAM161A OS=Cricetulus griseus OX=10029 GN=Fam161a PE=3 SV=1 CANONICAL=A0A9J7J6B3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HB20-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B3/entry#A0A9J7HB20-1", "sequence": { "sequence": "MAKLEKMYQDKLNIKDVWPVITREDYSSVSSSSVSEQNCPHPGLVTSYSEPDIGQSPSLSTTSDEELPSLEREAPGESRMTAYAKELINNMWTDFSVEDYMQYDSDVQTSKKTRKKQKPWVPRVTVPVPFQMTVREQKKREAAQKARPDPQSRQKLLKRDDDDDVECKKKFRANPAPSCILQPFYEDMVRQNEERRRTSKEKSKAALLASQKPFKFIAREEEKQAIREKQLRDLFKSKRKTKWFKARPVPRSIYRSAANDKSKDDEFYRDIRTQLKARELLQNSSWPCRQGQGHFRVPRSPGKPRGRHKCKCLCPDDGNFAEKQWKESSSEPSFQKHSTLCKQCGLHEYSCDSAKRQKVLADLRADEENLKEILWPHPSPRLKSPVRSACTKPRPCRCSPPMPTLSSRGREQAIRKSLEEKKMLEEERNRILTKQKQRMKELQKLVATRVKAYDSHQGLAQMSKSRVNQLRKSEKARMKEYRRELQERNEKLQQRPMLFERVAQRNARMAAEKRYSNTLEALGLSEEFVSEKGQGGKAPESFTREELRSRTSDKESSYEEEGENEEENYFIDANSQDSCKENTEEVKEGREENSEE", "length": 596, "header": "tr|A0A9J7HB20-1|A0A9J7J6B3_CRIGR Computationally mapped isoform of Protein FAM161A OS=Cricetulus griseus OX=10029 GN=Fam161a PE=3 SV=1 CANONICAL=A0A9J7J6B3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J6B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B3/entry#A0A9J7J6B3-1", "sequence": { "sequence": "MASLHRAARLVSGSLHLPVNPTTEPRVAQNEREDVLETLVSSALAVALEEEQKTETRPARALASGNSFPREKEDVTIQDIVDFSDVYHSNEEYFRKLRELKAAHAETMAKLEKMYQDKLNIKDVWPVITREDYSSVSSSSVSEQNCPHPGLVTSYSEPDIGQSPSLSTTSDEELPSLEREAPGESRMTAYAKELINNMWTDFSVEDYMQYDSDVQTSKKTRKKQKPWVPRVTVPVPFQMTVREQKKREAAQKARPDPQSRQKLLKRDDDDDVECKKKFRANPAPSCILQPFYEDMVRQNEERRRTSKEKSKAALLASQKPFKFIAREEEKQAIREKQLRDLFKSKRKTKWFKARPVPRSIYRSAANDKSKDDEFYRDIRTQLKARELLQNSSWPCRQGQGHFRVPRSPGKPRGRHKCKCLCPDDGNFAEKQWKESSSEPSFQKHSTLCKQCGLHEYSCDSAKRQKVLADLRADEENLKEILWPHPSPRLKSPVRSACTKPRPCRCSPPMPTLSSRGREQAIRKSLEEKKMLEEERNRILTKQKQRMKELQKLVATRVKAYDSHQGLAQMSKSRVNQLRKSEKARMKEYRRELQERNEKLQQRPMLFERVAQRNARMAAEKRYSNTLEALGLSEEFVSEKGQGGKAPESFTREELRSRTSDKESSYEEEGENEEENYFIDANSQDSCKENTEEVKEGREENSEE", "length": 703, "header": "tr|A0A9J7J6B3-1|A0A9J7J6B3_CRIGR Isoform 1 of Protein FAM161A OS=Cricetulus griseus OX=10029 GN=Fam161a PE=3 SV=1 CANONICAL=A0A9J7J6B3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J6F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B3/entry#A0A9J7J6F9-1", "sequence": { "sequence": "MASLHRAARLVSGSLHLPVNPTTEPRVAQNEREDVLETLVSSALAVALEEEQKTETRPARALASGNSFPREKEDVTIQDIVDFSDVYHSNEEYFRKLRELKAAHAETMAKLEKMYQDKLNIKDVWPVITREDYSSVSSSSVSEQNCPHPGLVTSYSEPDIGQSPSLSTTSDEELPSLEREAPGESRMTAYAKELINNMWTDFSVEDYMQYDSDVQTSKKTRKKQKPWVPRVTVPVPFQMTVREQKKREAAQKARPDPQSRQKLLKRDDDDDVECKKKFRANPAPSCILQPFYEDMVRQNEERRRTSKEKSKAALLASQKPFKFIAREEEKQAIREKQLRDLFKSKRKTKWFKARPVPRSIYRSAANDKSKDDEFYRDIRTQLKARELLQNSSWPCRQGQGHFRVPRSPGKPRGRHKCKCLCPDDGNFAEKQWKESSSEPSFQKHSTLCKQCGLHEYSCDSAKRQKVLADLRADEENLKEILWPHPSPRLKSPVRSACTKPRPCRCSPPMPTLSSRGREQAIRKSEKARMKEYRRELQERNEKLQQRPMLFERVAQRNARMAAEKRYSNTLEALGLSEEFVSEKGQGGKAPESFTREELRSRTSDKESSYEEEGENEEENYFIDANSQDSCKENTEEVKEGREENSEE", "length": 647, "header": "tr|A0A9J7J6F9-1|A0A9J7J6F9_CRIGR Computationally mapped isoform of Protein FAM161A OS=Cricetulus griseus OX=10029 GN=Fam161a PE=3 SV=1 CANONICAL=A0A9J7J6B3-1" }, "locus": {} }, { "isoform_ac": "G3HDR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B3/entry#G3HDR4-1", "sequence": { "sequence": "MASLHRAARLVSGSLHLPVNPTTEPRVAQNEREDVLETLVSSALAVALEEEQKTETRPARALASGNSFPREKEDVTIQDIVDFSDVYHSNEEYFRKLRELKAAHAETMAKLEKMYQDKLNIKDVWPVITREDYSSVSSSSVSEQNCPHPGLVTSYSEPDIGQSPSLSTTSDEELPSLEREAPGESRMTAYAKELINNMWTDFSVEDYMQYDSDVQTSKKTRKKQKPWVPRVTVPVPFQMTVREQKKREAAQKARPDPQSRQKLLKRDDDDDVECKKKFRANPAPSCILQPFYEDMVRQNEERRRTSKEKSKAALLASQKPFKFIAREEEKQAIREKQLRDLFKSKRKTKWFKARPVPRSIYRSAANDKSKDDEFYRDIRTQLKARELLQNSSWPCRQGQGHFRVPRSPGKPRGRHKCKCLCPDDGNFAEKQWKESSSEPSFQKHSTLCKQCGLHEYSCDSAKRQKVLADLRADEENLKEILWPHPSPRLKSPVRSACTKPRPCRCSPPMPTLSSRGREQAIRKSEKARMKEYRRELQERNEKLQQRPMLFERVAQVVFVGM", "length": 561, "header": "tr|G3HDR4-1|A0A9J7J6B3_CRIGR Computationally mapped isoform of Protein FAM161A OS=Cricetulus griseus OX=10029 GN=Fam161a PE=3 SV=1 CANONICAL=A0A9J7J6B3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HDR4", "url": "https://www.uniprot.org/uniprotkb/G3HDR4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HDR4", "url": "https://www.uniprot.org/uniprotkb/G3HDR4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770716", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770716", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6B3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B3" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6B3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B3" } ], "pmid": "" }, { "name": "photoreceptor connecting cilium", "id": "GO:0032391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032391", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6B3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6B3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 390, "end_pos": 392 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J6W5-1", "uniprot_ac": "A0A9J7J6W5", "uniprot_id": "A0A9J7J6W5_CRIGR", "mass": { "chemical_mass": 55659.0, "monoisotopic_mass": 55659.0 }, "refseq": { "ac": "XP_027247574", "name": "importin subunit alpha-3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247574" }, "gene_names": [ { "name": "Kpna4", "type": "recommended", "evidence": [ { "id": "A0A9J7J6W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6W5" } ] }, { "name": "Kpna4", "type": "synonym", "evidence": [ { "id": "XP_027247574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247574" } ] } ], "protein_names": [ { "name": "Importin subunit alpha", "type": "recommended", "evidence": [ { "id": "A0A9J7J6W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6W5/entry#names_and_taxonomy" } ] }, { "name": "importin subunit alpha-3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027247574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247574" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027247574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247574" } ] }, { "annotation": "Functions in nuclear protein import.", "evidence": [ { "database": "UniProtKB", "id": "G3HHC3", "url": "https://www.uniprot.org/uniprotkb/G3HHC3#function" }, { "database": "UniProtKB", "id": "PIRNR005673", "url": "https://www.uniprot.org/uniprotkb/PIRNR005673#function" }, { "database": "UniProtKB", "id": "A0A9J7J6W5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6W5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6W5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6W5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Kpna4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6W5", "locus": {} } ], "crossref": [ { "id": "A0A9J7J6W5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J6W5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100757318", "url": "https://www.ncbi.nlm.nih.gov/gene/100757318", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024931", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024931", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036975", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036975", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757318", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757318", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IPRDGFN", "url": "https://omabrowser.org/oma/group/IPRDGFN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J6W5", "url": "https://www.orthodb.org/?gene=A0A9J7J6W5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23316", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23316", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00514", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00514", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01749", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01749", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16186", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16186", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027247574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247574", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7J6W5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6W5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J6W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6W5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HHC3", "url": "https://www.uniprot.org/uniprotkb/G3HHC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HHC3-1", "url": "https://www.uniprot.org/uniprotkb/G3HHC3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLTTMRRQRNEVVVELRKNKRDEHLLKRRNVPQEDICEDSDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLRSSHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDPSLVPEAVQGGTFGFNSSANVPTEGFQF", "length": 502, "header": "tr|A0A9J7J6W5-1|A0A9J7J6W5_CRIGR Isoform 1 of Importin subunit alpha OS=Cricetulus griseus OX=10029 GN=Kpna4 PE=3 SV=1 CANONICAL=A0A9J7J6W5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7J6W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6W5/entry#A0A9J7J6W5-1", "sequence": { "sequence": "MWLTTMRRQRNEVVVELRKNKRDEHLLKRRNVPQEDICEDSDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLRSSHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDPSLVPEAVQGGTFGFNSSANVPTEGFQF", "length": 502, "header": "tr|A0A9J7J6W5-1|A0A9J7J6W5_CRIGR Isoform 1 of Importin subunit alpha OS=Cricetulus griseus OX=10029 GN=Kpna4 PE=3 SV=1 CANONICAL=A0A9J7J6W5-1" }, "locus": {} }, { "isoform_ac": "G3HHC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6W5/entry#G3HHC3-1", "sequence": { "sequence": "MRRQRNEVVVELRKNKRDEHLLKRRNVPQEDICEDSDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLRSSHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDPSLVPEAVQGGTFGFNSSANVPTEGFQF", "length": 497, "header": "tr|G3HHC3-1|A0A9J7J6W5_CRIGR Computationally mapped isoform of Importin subunit alpha OS=Cricetulus griseus OX=10029 GN=Kpna4 PE=3 SV=1 CANONICAL=A0A9J7J6W5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HHC3", "url": "https://www.uniprot.org/uniprotkb/G3HHC3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HHC3", "url": "https://www.uniprot.org/uniprotkb/G3HHC3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757318", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757318", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VC39-1", "protein_name": "Importin subunit alpha", "gene_name": "KPNA4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADSEKLDNQRLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDPSLVPEAIQGGTFGFNSSANVPTEGFQF", "length": 521 }, "evidence": [ { "id": "A0A9J7J6W5", "url": "https://omabrowser.org/oma/group/A0A9J7J6W5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F7FQB8-1", "protein_name": "Karyopherin subunit alpha 4", "gene_name": "Kpna4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGVAAKPGPQIEAASPSQPAAHSAAVAAAGPAVVFARAAVVPGLRAGEGSQGAEAGRARGRERTGGRRRRRPASWERRCGAVVGADPAGPGRGGRVAGPAMADNEKLDNQRLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPQEDICEDSDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDQAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDPSLVPESVQGGTFGFNSSTNVPTEGFQF", "length": 621 }, "evidence": [ { "id": "A0A9J7J6W5", "url": "https://omabrowser.org/oma/group/A0A9J7J6W5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O00629-1", "protein_name": "Importin subunit alpha-3", "gene_name": "KPNA4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADNEKLDNQRLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDPSLVPEAIQGGTFGFNSSANVPTEGFQF", "length": 521 }, "evidence": [ { "id": "A0A9J7J6W5", "url": "https://omabrowser.org/oma/group/A0A9J7J6W5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35343-1", "protein_name": "Importin subunit alpha-3", "gene_name": "Kpna4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADNEKLDNQRLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPQEDICEDSDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDQAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDPSLVPESVQGGTFGFNSSTNVPTEGFQF", "length": 521 }, "evidence": [ { "id": "A0A9J7J6W5", "url": "https://omabrowser.org/oma/group/A0A9J7J6W5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V455-1", "protein_name": "Importin subunit alpha", "gene_name": "Kap-alpha3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTSMEQNRLQNFKNKGKDQDEMRRRRNEVTVELRKNKREETILKRRNVPNLDSNTDEEEQLSSSIDLKKLAKAAADATKPEQQLAAVQAARKLLSSDKNPPINDLIQSDILPILVECLKQHNHTMLQFEAAWALTNIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLRDFVIKHGVVQPLLSFIKPDIPITFLRNVTWVIVNLCRNKDPAPPTATIHEILPALNVLIHHTDTNILVDTVWAISYLTDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVVLNYDALSYFPGLLSHPKEKIRKEAVWFLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKEAAWAISNLTISGNREQVFTLIKEGVIPPFCDLLSCQDTQVINVVLDGLNNMLKVADSHVEAVANCIEECEGLAKIERLQSHENVEIYKLAYEIIDQYFTDEGEQTNMAPTSDGAQYNFDPHADRLTMNSFNF", "length": 514 }, "evidence": [ { "id": "A0A9J7J6W5", "url": "https://omabrowser.org/oma/group/A0A9J7J6W5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6W5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6W5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6W5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6W5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6W5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6W5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nuclear import signal receptor activity", "id": "GO:0061608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061608", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6W5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6W5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J6W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6W5" }, { "id": "PS51214", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IBB", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 39, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 }, { "start_pos": 333, "end_pos": 335 }, { "start_pos": 375, "end_pos": 377 }, { "start_pos": 490, "end_pos": 492 }, { "start_pos": 51, "end_pos": 53 }, { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J467-1", "uniprot_ac": "A0A9J7J467", "uniprot_id": "A0A9J7J467_CRIGR", "mass": { "chemical_mass": 47184.0, "monoisotopic_mass": 47184.0 }, "refseq": { "ac": "XP_007643116", "name": "muscleblind-like protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643116" }, "gene_names": [ { "name": "Mbnl1", "type": "recommended", "evidence": [ { "id": "A0A9J7J467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467" } ] }, { "name": "Mbnl1", "type": "synonym", "evidence": [ { "id": "XP_007643116", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643116" } ] } ], "protein_names": [ { "name": "Muscleblind-like protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7J467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#names_and_taxonomy" } ] }, { "name": "muscleblind-like protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007643116", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643116" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614060.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007643116", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643116" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J467", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mbnl1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467", "locus": {} } ], "crossref": [ { "id": "100771199", "url": "https://www.ncbi.nlm.nih.gov/gene/100771199", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054429", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054429", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771199", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771199", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LM97", "url": "https://www.orthodb.org/?gene=A0A8C2LM97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7EZT4", "url": "https://www.orthodb.org/?gene=A0A9J7EZT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7F0V1", "url": "https://www.orthodb.org/?gene=A0A9J7F0V1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7F285", "url": "https://www.orthodb.org/?gene=A0A9J7F285", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7F3Z2", "url": "https://www.orthodb.org/?gene=A0A9J7F3Z2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7F4D1", "url": "https://www.orthodb.org/?gene=A0A9J7F4D1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7F4Z6", "url": "https://www.orthodb.org/?gene=A0A9J7F4Z6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7F502", "url": "https://www.orthodb.org/?gene=A0A9J7F502", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7F5A8", "url": "https://www.orthodb.org/?gene=A0A9J7F5A8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J467", "url": "https://www.orthodb.org/?gene=A0A9J7J467", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J472", "url": "https://www.orthodb.org/?gene=A0A9J7J472", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J6U9", "url": "https://www.orthodb.org/?gene=A0A9J7J6U9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J8S9", "url": "https://www.orthodb.org/?gene=A0A9J7J8S9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J8T8", "url": "https://www.orthodb.org/?gene=A0A9J7J8T8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JAB1", "url": "https://www.orthodb.org/?gene=A0A9J7JAB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HL93", "url": "https://www.orthodb.org/?gene=G3HL93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12675:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12675:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14608", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007643116", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643116", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LM97", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LM97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LM97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LM97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EZT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EZT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F0V1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F0V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0V1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F285", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F285", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F285-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F285-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F3Z2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F3Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F4D1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F4D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4D1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F4Z6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4Z6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F4Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4Z6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F502", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F502", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F502-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F502-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F5A8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F5A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5A8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6H7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6H7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6H7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7C0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7C0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J467", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J467-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J472", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J472", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J472-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J472-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J6U9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J6U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8S9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8T8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8T8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JAB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JAB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HL93", "url": "https://www.uniprot.org/uniprotkb/G3HL93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HL93-1", "url": "https://www.uniprot.org/uniprotkb/G3HL93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVNLMQQSFQKRGGDCISRWEGSPYNTGSDTNYQYCTVEPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPGSILCMTPATSVVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 436, "header": "tr|A0A9J7J467-1|A0A9J7J467_CRIGR Isoform 1 of Muscleblind-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LM97-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A8C2LM97-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 387, "header": "tr|A0A8C2LM97-1|A0A8C2LM97_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X9 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EZT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A9J7EZT4-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVNLMQQSFQKRGGDCISRWEGSPYNTGSDTNYQYCTVEPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLALANMQLQQHTAFLPPGSILCMTPATSVVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 401, "header": "tr|A0A9J7EZT4-1|A0A9J7J467_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F0V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A9J7F0V1-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVNLMQQSFQKRGGDCISRWEGSPYNTGSDTNYQYCTVEPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPGSILCMTPATSVVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 418, "header": "tr|A0A9J7F0V1-1|A0A9J7J467_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F285-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A9J7F285-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVNLMQQSFQKRGGDCISRWEGSPYNTGSDTNYQYCTVEPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPDTHNICRTSD", "length": 384, "header": "tr|A0A9J7F285-1|A0A9J7J467_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F3Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A9J7F3Z2-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 369, "header": "tr|A0A9J7F3Z2-1|A0A9J7J467_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F4D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A9J7F4D1-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVNLMQQSFQKRGGDCISRWEGSPYNTGSDTNYQYCTVEPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLALANMQLQQHTAFLPPVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 389, "header": "tr|A0A9J7F4D1-1|A0A9J7J467_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F4Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A9J7F4Z6-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPGSILCMTPATSVVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 399, "header": "tr|A0A9J7F4Z6-1|A0A9J7J467_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F502-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A9J7F502-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVNLMQQSFQKRGGDCISRWEGSPYNTGSDTNYQYCTVEPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 406, "header": "tr|A0A9J7F502-1|A0A9J7J467_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F5A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A9J7F5A8-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVNLMQQSFQKRGGDCISRWEGSPYNTGSDTNYQYCTVEPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMALANMQLQQHTAFLPPGSILCMTPATSVVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 383, "header": "tr|A0A9J7F5A8-1|A0A9J7J467_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H6H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A9J7H6H7-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMALANMQLQQHTAFLPPGSILCMTPATSVVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 346, "header": "tr|A0A9J7H6H7-1|A0A9J7J467_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A9J7H7C0-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVNLMQQSFQKRGGDCISRWEGSPYNTGSDTNYQYCTVEPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLALANMQLQQHTAFLPPGSILCMTPATSVDTHNICRTSD", "length": 361, "header": "tr|A0A9J7H7C0-1|A0A9J7J467_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J467-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A9J7J467-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVNLMQQSFQKRGGDCISRWEGSPYNTGSDTNYQYCTVEPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPGSILCMTPATSVVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 436, "header": "tr|A0A9J7J467-1|A0A9J7J467_CRIGR Isoform 1 of Muscleblind-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J472-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A9J7J472-1", "sequence": { "sequence": "MAMLAQQMQLANAMMPGTPLQPVNLMQQSFQKRGGDCISRWEGSPYNTGSDTNYQYCTVEPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPGSILCMTPATSVVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 344, "header": "tr|A0A9J7J472-1|A0A9J7J472_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X16 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J6U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A9J7J6U9-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVNLMQQSFQKRGGDCISRWEGSPYNTGSDTNYQYCTVEPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMALANMQLQQHTAFLPPVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 371, "header": "tr|A0A9J7J6U9-1|A0A9J7J6U9_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X13 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J8S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A9J7J8S9-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVNLMQQSFQKRGGDCISRWEGSPYNTGSDTNYQYCTVEPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 424, "header": "tr|A0A9J7J8S9-1|A0A9J7J8S9_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J8T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A9J7J8T8-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVNLMQQSFQKRGGDCISRWEGSPYNTGSDTNYQYCTVEPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLALANMQLQQHTAFLPPDTHNICRTSD", "length": 349, "header": "tr|A0A9J7J8T8-1|A0A9J7J8T8_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X17 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JAB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#A0A9J7JAB1-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVNLMQQSFQKRGGDCISRWEGSPYNTGSDTNYQYCTVEPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPGSILCMTPATSVDTHNICRTSD", "length": 396, "header": "tr|A0A9J7JAB1-1|A0A9J7JAB1_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X7 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} }, { "isoform_ac": "G3HL93-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467/entry#G3HL93-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGTPLQPVPMFSVAPSLATNASAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPGSILCMTPATSVVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 381, "header": "tr|G3HL93-1|A0A9J7J467_CRIGR Computationally mapped isoform of Muscleblind-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mbnl1 PE=3 SV=1 CANONICAL=A0A9J7J467-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HL93", "url": "https://www.uniprot.org/uniprotkb/G3HL93" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HL93", "url": "https://www.uniprot.org/uniprotkb/G3HL93" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771199", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771199", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J467", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J467", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J467", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J467", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J467", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J467" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 41, "start_aa": "Trp", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J716-1", "uniprot_ac": "A0A9J7J716", "uniprot_id": "A0A9J7J716_CRIGR", "mass": { "chemical_mass": 50979.0, "monoisotopic_mass": 50979.0 }, "refseq": { "ac": "XP_003510882", "name": "beta-1,3-galactosyltransferase 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510882" }, "gene_names": [ { "name": "B3galt4", "type": "recommended", "evidence": [ { "id": "A0A9J7J716", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J716" } ] }, { "name": "B3galt4", "type": "synonym", "evidence": [ { "id": "XP_003510882", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510882" } ] } ], "protein_names": [ { "name": "Hexosyltransferase", "type": "recommended", "evidence": [ { "id": "A0A9J7J716", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J716/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "A0A9J7J716", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J716/entry#names_and_taxonomy" } ] }, { "name": "beta-1,3-galactosyltransferase 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003510882", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510882" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614972.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003510882.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510882", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510882" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J716", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J716" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "B3galt4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J716", "locus": {} } ], "crossref": [ { "id": "A0A9J7J716", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J716", "database": "AlphaFoldDB", "categories": [] }, { "id": "100751197", "url": "https://www.ncbi.nlm.nih.gov/gene/100751197", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751197", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751197", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SHKLDPW", "url": "https://omabrowser.org/oma/group/SHKLDPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J716", "url": "https://www.orthodb.org/?gene=A0A9J7J716", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3I6W7", "url": "https://www.orthodb.org/?gene=G3I6W7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11214", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11214", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11214:SF378", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11214:SF378", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01762", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01762", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510882", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510882", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7J716", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J716", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J716-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J716-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3I6W7", "url": "https://www.uniprot.org/uniprotkb/G3I6W7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3I6W7-1", "url": "https://www.uniprot.org/uniprotkb/G3I6W7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLGLGQVCGARCLATSGRQRHDGKAAGEGRDGGSELGVRAAARKRVTGPLRWAWGCASRSAGPPVHRPPCLLGSSWLGLLASAPGALTVVPAGPRARLAMPLGLFRRLLLAALLLVIVWTLFGPSGFGEELLSLSLASLLPAPASPGPPLALPRLLIPNPQACGGPGPPPFLLVLVCTAPEHLSQRRAIRGSWGAIREARGFRVQTLFLLGEPTGQHVPDLASESAAHKDILQAAFQDSYRNLTLKTLSGLNWVRKYCPGARYILKTDDDVYVNVPELVSELIQRGGPSERWQKGRGPQEGTTAAHEEHQGQAVPLLYLGRVHWRVSPTRTPGARHHVSEELWPETWGPFPPYASGTGYVLSASAVHLILKVASRAPHLPLEDVFVGVSARRGGLAPTHCVKLAGATHYPLDRCCYGKFLLTSHRLDPWKMQEAWKLVNRLHGESAEPFCSWPQAFLGVLRCRFIAWLNS", "length": 471, "header": "tr|A0A9J7J716-1|A0A9J7J716_CRIGR Isoform 1 of Hexosyltransferase OS=Cricetulus griseus OX=10029 GN=B3galt4 PE=3 SV=1 CANONICAL=A0A9J7J716-1" }, "isoforms": [ { "isoform_ac": "A0A9J7J716-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J716/entry#A0A9J7J716-1", "sequence": { "sequence": "MRLGLGQVCGARCLATSGRQRHDGKAAGEGRDGGSELGVRAAARKRVTGPLRWAWGCASRSAGPPVHRPPCLLGSSWLGLLASAPGALTVVPAGPRARLAMPLGLFRRLLLAALLLVIVWTLFGPSGFGEELLSLSLASLLPAPASPGPPLALPRLLIPNPQACGGPGPPPFLLVLVCTAPEHLSQRRAIRGSWGAIREARGFRVQTLFLLGEPTGQHVPDLASESAAHKDILQAAFQDSYRNLTLKTLSGLNWVRKYCPGARYILKTDDDVYVNVPELVSELIQRGGPSERWQKGRGPQEGTTAAHEEHQGQAVPLLYLGRVHWRVSPTRTPGARHHVSEELWPETWGPFPPYASGTGYVLSASAVHLILKVASRAPHLPLEDVFVGVSARRGGLAPTHCVKLAGATHYPLDRCCYGKFLLTSHRLDPWKMQEAWKLVNRLHGESAEPFCSWPQAFLGVLRCRFIAWLNS", "length": 471, "header": "tr|A0A9J7J716-1|A0A9J7J716_CRIGR Isoform 1 of Hexosyltransferase OS=Cricetulus griseus OX=10029 GN=B3galt4 PE=3 SV=1 CANONICAL=A0A9J7J716-1" }, "locus": {} }, { "isoform_ac": "G3I6W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J716/entry#G3I6W7-1", "sequence": { "sequence": "MPLGLFRRLLLAALLLVIVWTLFGPSGFGEELLSLSLASLLPAPASPGPPLALPRLLIPNPQACGGPGPPPFLLVLVCTAPEHLSQRRAIRGSWGAIREARGFRVQTLFLLGEPTGQHVPDLASESAAHKDILQAAFQDSYRNLTLKTLSGLNWVRKYCPGARYILKTDDDVYVNVPELVSELIQRGGPSERWQKGRGPQEGTTAAHEEHQGQAVPLLYLGRVHWRVSPTRTPGARHHVSEELWPETWGPFPPYASGTGYVLSASAVHLILKVASRAPHLPLEDVFVGVSARRGGLAPTHCVKLAGATHYPLDRCCYGKFLLTSHRLDPWKMQEAWKLVNRLHGESAEPFCSWPQAFLGVLRCRFIAWLNS", "length": 371, "header": "tr|G3I6W7-1|A0A9J7J716_CRIGR Computationally mapped isoform of Hexosyltransferase OS=Cricetulus griseus OX=10029 GN=B3galt4 PE=3 SV=1 CANONICAL=A0A9J7J716-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I6W7", "url": "https://www.uniprot.org/uniprotkb/G3I6W7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I6W7", "url": "https://www.uniprot.org/uniprotkb/G3I6W7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751197", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751197", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RZT4-1", "protein_name": "Hexosyltransferase", "gene_name": "B3GALT4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRLSLSRRLLLAALLLVIIWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLIPNEEACGGPGVPPFLLILVCTAPDNLNQRNAIRASWGRLREARGLRVQTLFLLGEPSGGSRENDLARESAAHGDIVQAAFQDSYRNLTLKTLSGLNWADKHCPMARYILKTDDDVFVNVPELVSELVRRGGHWEQWEQEPQRKAKVGDEEGGEGSPTSGSQPVPLLYLGRVHWRVHPSRTPGGRHQIAEEQWPPAWGPFPPYASGTGYLLSASAVELILKVASRAPPLPLEDVFVGVSARRGGLTPTHCVRLAGATHYPLDRCCYGRFLLTSHRLDPREMQEAWELVGGSDGRRTVPFCSWLQGVLGILRCRVIAWLHS", "length": 377 }, "evidence": [ { "id": "A0A9J7J716", "url": "https://omabrowser.org/oma/group/A0A9J7J716/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O88178-1", "protein_name": "Beta-1,3-galactosyltransferase 4", "gene_name": "B3galt4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLSLFRRLLLAVLLLVIIWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLIPNPQACGGSGPPPFLLILVCTAPEHLNQRNAIRGSWGAIREARGFRVQTLFLLGEPMGQQFADLASESAAQGDVLQASFQDSYRNLTLKTLTGLNWVNKYCPMARYILKTDDDVYVNVPELVSELIQRGGPSEQWQKGKEPQEETTAVHKEHKGQAVPLLYLGRVHWRVRPTRTPESRHHVSEELWPENWGPFPPYASGTGYVLSISAVQLILKVASRAPYLPLEDVFVGVSARRVGLAPTHCVKLAGATHYPLDRCCYGKFLLTSHKVDPWKMQEAWKLVRGLNGRRTEPFCSWLQGFLGTLRCRFIAWLNS", "length": 371 }, "evidence": [ { "id": "A0A9J7J716", "url": "https://omabrowser.org/oma/group/A0A9J7J716/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O96024-1", "protein_name": "Beta-1,3-galactosyltransferase 4", "gene_name": "B3GALT4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQLRLFRRLLLAALLLVIVWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLIPNQEACSGPGAPPFLLILVCTAPENLNQRNAIRASWGGLREARGLRVQTLFLLGEPNAQHPVWGSQGSDLASESAAQGDILQAAFQDSYRNLTLKTLSGLNWAEKHCPMARYVLKTDDDVYVNVPELVSELVLRGGRWGQWERSTEPQREAEQEGGQVLHSEEVPLLYLGRVHWRVNPSRTPGGRHRVSEEQWPHTWGPFPPYASGTGYVLSASAVQLILKVASRAPLLPLEDVFVGVSARRGGLAPTQCVKLAGATHYPLDRCCYGKFLLTSHRLDPWKMQEAWKLVGGSDGERTAPFCSWFQGVLGILRCRAIAWLQS", "length": 378 }, "evidence": [ { "id": "A0A9J7J716", "url": "https://omabrowser.org/oma/group/A0A9J7J716/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62271-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "Rps18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLVIPEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGRTVGVSKKK", "length": 152 }, "evidence": [ { "id": "A0A9J7J716", "url": "https://omabrowser.org/oma/group/A0A9J7J716/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Z0F0-1", "protein_name": "Beta-1,3-galactosyltransferase 4", "gene_name": "B3galt4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLSLFRRVLLAVLLLVIIWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLISNSHACGGSGPPPFLLILVCTAPEHLNQRNAIRASWGAIREARGFRVQTLFLLGKPRRQQLADLSSESAAHRDILQASFQDSYRNLTLKTLSGLNWVNKYCPMARYILKTDDDVYVNVPELVSELIQRGGPSEQWQKGKEAQEETTAIHEEHRGQAVPLLYLGRVHWRVRPTRTPESRHHVSEELWPENWGPFPPYASGTGYVLSISAVQLILKVASRAPPLPLEDVFVGVSARRGGLAPTHCVKLAGATHYPLDRCCYGKFLLTSHKVDPWQMQEAWKLVSGMNGERTAPFCSWLQGFLGTLRCRFIAWFSS", "length": 371 }, "evidence": [ { "id": "A0A9J7J716", "url": "https://omabrowser.org/oma/group/A0A9J7J716/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J716", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J716" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J716", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J716" } ], "pmid": "" }, { "name": "ganglioside biosynthetic process", "id": "GO:0001574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001574", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J716", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J716" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J716", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J716" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity", "id": "GO:0008499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008499", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J716", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J716" } ], "pmid": "" }, { "name": "hexosyltransferase activity", "id": "GO:0016758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016758", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J716", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J716" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 243, "end_pos": 245 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613875.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502120", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502120" } ] }, { "annotation": "Hydrolase highly specific for thiamine triphosphate (ThTP).", "evidence": [ { "database": "UniProtKB", "id": "G3HDG0", "url": "https://www.uniprot.org/uniprotkb/G3HDG0#function" }, { "database": "UniProtKB", "id": "ARBA00002106", "url": "https://www.uniprot.org/uniprotkb/ARBA00002106#function" }, { "database": "UniProtKB", "id": "PIRNR036561", "url": "https://www.uniprot.org/uniprotkb/PIRNR036561#function" }, { "database": "UniProtKB", "id": "A0A9J7J639", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J639", "url": 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{ "id": "IPR033469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764351", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764351", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HWLRHRE", "url": "https://omabrowser.org/oma/group/HWLRHRE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J639", "url": "https://www.orthodb.org/?gene=A0A9J7J639", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HDG0", "url": "https://www.orthodb.org/?gene=G3HDG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14586", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14586", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14586:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14586:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01928", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01928", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502120", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502120", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11744", "url": "https://www.rhea-db.org/rhea/11744", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7J639", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J639-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HDG0", "url": "https://www.uniprot.org/uniprotkb/G3HDG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HDG0-1", "url": "https://www.uniprot.org/uniprotkb/G3HDG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCLLRSSRTRGSPLTSRTLEHTVVNSWQTCVAGNMAQGLIEVERKFVPGPDMEERLQELGGTLERRVTFRDTYYDTSELSLMRSDHWLRQRQGSGWELKCPGVAGISGPHNEYVELTSESAIVAELFELLEAEEPEIAGVAAVLGPLKLQEVASFITTRSSWKLALSEAHEQEPLLRVDLDSTDFGYAVGEVEVMVREKAEVPAALEKIFSFSRMLGVPAQEKAPAKLLVYLQRFRPLDYQRLLEANSSSEATGDLTS", "length": 258, "header": "tr|A0A9J7J639-1|A0A9J7J639_CRIGR Isoform 1 of Thiamine-triphosphatase OS=Cricetulus griseus OX=10029 GN=Thtpa PE=3 SV=1 CANONICAL=A0A9J7J639-1" }, "isoforms": [ { "isoform_ac": "A0A9J7J639-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639/entry#A0A9J7J639-1", "sequence": { "sequence": 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{} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HDG0", "url": "https://www.uniprot.org/uniprotkb/G3HDG0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8CGV7-1", "protein_name": "Thiamine-triphosphatase", "gene_name": "Thtpa", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQGLIEVERKFTPGPDTEERLQKLGATLEHRVTFRDTYYDTSELSLMLSDHWLRQREGSGWEFKCPGVTGVSGPHNEYVEVTSESAIVTQLFELLGSGEQETAGVAAVLGRLKLQEVASFITTRSSWKLALSGAHEEESLLTVDLDSTDFGYAVGEVEAVVHEKAEVPAALEKIISVSSMLGVPAQEKAPAKLLVYLQRFRPQDYQRLLEADSSGEATGDSVP", "length": 224 }, "evidence": [ { "id": "A0A9J7J639", "url": "https://omabrowser.org/oma/group/A0A9J7J639/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8JZL3-1", "protein_name": "Thiamine-triphosphatase", "gene_name": "Thtpa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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biosynthetic process", "id": "GO:0009229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009229", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J639", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639" } ], "pmid": "" }, { "name": "thiamine metabolic process", "id": "GO:0006772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006772", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J639", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639" } ], "pmid": "" }, { "name": "thiamine diphosphate metabolic process", "id": "GO:0042357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042357", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J639", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11744", "name": "", "equation": "thiamine triphosphate + 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"CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 159, "end_pos": 159, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7J639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639#function" }, { "id": "A0A9J7J639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639" }, { "id": "PIRSR036561-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR036561-2" } ], "binding_site_uniprot": 179, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 179, "end_pos": 179, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7J639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639#function" }, { "id": "A0A9J7J639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639" }, { "id": "PIRSR036561-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR036561-2" } ], "binding_site_uniprot": 191, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 191, "end_pos": 191, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7J639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639#function" }, { "id": "A0A9J7J639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639" }, { "id": "PIRSR036561-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR036561-2" } ], "binding_site_uniprot": 193, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 193, "end_pos": 193, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7J639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639#function" }, { "id": "A0A9J7J639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639" }, { "id": "PIRSR036561-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR036561-2" } ], "binding_site_uniprot": 41, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 41, "end_pos": 41, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7J639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639#function" }, { "id": "A0A9J7J639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J639" }, { "id": "PIRSR036561-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR036561-2" } ], "binding_site_uniprot": 43, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 43, "end_pos": 43, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "G3HDG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDG0#function" }, { "id": "G3HDG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDG0" }, { "id": "PIRSR036561-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR036561-2" } ], "binding_site_uniprot": 7, "amino_acid": "Ser", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 7, "end_pos": 7, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "G3HDG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDG0#function" }, { "id": "G3HDG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDG0" }, { "id": "PIRSR036561-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR036561-2" } ], "binding_site_uniprot": 9, "amino_acid": "Thr", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 9, "end_pos": 9, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.1.28", "ec_name": "thiamine triphosphate + H2O = thiamine diphosphate + phosphate + H(+).", "evidence": [ { "id": "3.6.1.28", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.28" }, { "id": "3.6.1.28", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.1.28" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 247, "end_pos": 249 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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"field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HDF5-1", "uniprot_ac": "A0A9J7HDF5", "uniprot_id": "A0A9J7HDF5_CRIGR", "mass": { "chemical_mass": 73102.0, "monoisotopic_mass": 73102.0 }, "refseq": { "ac": "XP_035308171", "name": "dihydropyrimidinase-related protein 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308171" }, "gene_names": [ { "name": "Dpysl2", "type": "recommended", "evidence": [ { "id": "A0A9J7HDF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" } ] }, { "name": "Dpysl2", "type": "synonym", "evidence": [ { "id": "XP_035308171", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308171" } ] } ], "protein_names": [ { "name": "Dihydropyrimidinase-related protein 2", "type": "recommended", "evidence": [ { "id": "A0A9J7HDF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5/entry#names_and_taxonomy" } ] }, { "name": "dihydropyrimidinase-related protein 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_035308171", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308171" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308171", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308171" } ] }, { "annotation": "Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.", "evidence": [ { "database": "UniProtKB", "id": "G3HNK4", "url": "https://www.uniprot.org/uniprotkb/G3HNK4#function" }, { "database": "UniProtKB", "id": "ARBA00024777", "url": "https://www.uniprot.org/uniprotkb/ARBA00024777#function" }, { "database": "UniProtKB", "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dpysl2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5", "locus": {} } ], "crossref": [ { "id": "A0A9J7HDF5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HDF5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01314", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01314", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759148", "url": "https://www.ncbi.nlm.nih.gov/gene/100759148", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011778", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011778", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759148", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759148", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EYTPFEG", "url": "https://omabrowser.org/oma/group/EYTPFEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7HDF5", "url": "https://www.orthodb.org/?gene=A0A9J7HDF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HNK4", "url": "https://www.orthodb.org/?gene=G3HNK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11647", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11647", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11647:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11647:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01979", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01979", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308171", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308171", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HNK4", "url": "https://www.uniprot.org/uniprotkb/G3HNK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HNK4-1", "url": "https://www.uniprot.org/uniprotkb/G3HNK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADRKQSGKAAEDEEVPAFFKNLGSGSPKPRQKFCGMFCPVEGSSENKTIDFDSLSVGRGSGQVVAQQRDVAHLGPDPHRQSRRGSGEPSVESGRKVEIRRASGKEALQNIYDQSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYVTKVMSKSAADVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "length": 673, "header": "tr|A0A9J7HDF5-1|A0A9J7HDF5_CRIGR Isoform 1 of Dihydropyrimidinase-related protein 2 OS=Cricetulus griseus OX=10029 GN=Dpysl2 PE=3 SV=1 CANONICAL=A0A9J7HDF5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HDF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5/entry#A0A9J7HDF5-1", "sequence": { "sequence": "MADRKQSGKAAEDEEVPAFFKNLGSGSPKPRQKFCGMFCPVEGSSENKTIDFDSLSVGRGSGQVVAQQRDVAHLGPDPHRQSRRGSGEPSVESGRKVEIRRASGKEALQNIYDQSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYVTKVMSKSAADVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "length": 673, "header": "tr|A0A9J7HDF5-1|A0A9J7HDF5_CRIGR Isoform 1 of Dihydropyrimidinase-related protein 2 OS=Cricetulus griseus OX=10029 GN=Dpysl2 PE=3 SV=1 CANONICAL=A0A9J7HDF5-1" }, "locus": {} }, { "isoform_ac": "G3HNK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5/entry#G3HNK4-1", "sequence": { "sequence": "MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYVTKVMSKSAADVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "length": 572, "header": "tr|G3HNK4-1|A0A9J7HDF5_CRIGR Computationally mapped isoform of Dihydropyrimidinase-related protein 2 OS=Cricetulus griseus OX=10029 GN=Dpysl2 PE=3 SV=1 CANONICAL=A0A9J7HDF5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 615, "start_aa": "Thr", "end_pos": 615, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr615", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HNK4", "url": "https://www.uniprot.org/uniprotkb/G3HNK4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HNK4", "url": "https://www.uniprot.org/uniprotkb/G3HNK4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759148", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759148", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RJT3-1", "protein_name": "Dihydropyrimidinase-related protein 2", "gene_name": "DPYSL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAERKQSGKAAEDEEVPAFFKNLGSGSPKPRQKFCGMFCPVEGSSENKTIDFDSLSVGRGSGQVVAQQRDVAHLGPDPQPPYSRQGRRAGGEPSVESGRKVEIRRASGKEALQNINDQSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLSAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYITKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSIIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "length": 677 }, "evidence": [ { "id": "A0A9J7HDF5", "url": "https://omabrowser.org/oma/group/A0A9J7HDF5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O02675-1", "protein_name": "Dihydropyrimidinase-related protein 2", "gene_name": "DPYSL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGVQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYITKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "length": 572 }, "evidence": [ { "id": "A0A9J7HDF5", "url": "https://omabrowser.org/oma/group/A0A9J7HDF5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O08553-1", "protein_name": "Dihydropyrimidinase-related protein 2", "gene_name": "Dpysl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYVTKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "length": 572 }, "evidence": [ { "id": "A0A9J7HDF5", "url": "https://omabrowser.org/oma/group/A0A9J7HDF5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P47942-1", "protein_name": "Dihydropyrimidinase-related protein 2", "gene_name": "Dpysl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYVTKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "length": 572 }, "evidence": [ { "id": "A0A9J7HDF5", "url": "https://omabrowser.org/oma/group/A0A9J7HDF5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q16555-1", "protein_name": "Dihydropyrimidinase-related protein 2", "gene_name": "DPYSL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "length": 572 }, "evidence": [ { "id": "A0A9J7HDF5", "url": "https://omabrowser.org/oma/group/A0A9J7HDF5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" } ], "pmid": "" }, { "name": "plasma membrane bounded cell projection", "id": "GO:0120025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120025", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" } ], "pmid": "" }, { "name": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides", "id": "GO:0016812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016812", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 668, "end_pos": 670, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HDF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" }, { "id": "PF01979", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01979" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amidohydrolase-related", "eco_id": "ECO_0000259", "start_pos": 165, "end_pos": 554, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A9J7HDF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5#function" }, { "id": "A0A9J7HDF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" }, { "id": "PIRSR611778-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR611778-2" } ], "binding_site_uniprot": 174, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 174, "end_pos": 174, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "G3HNK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HNK4#function" }, { "id": "G3HNK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HNK4" }, { "id": "PIRSR611778-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR611778-2" } ], "binding_site_uniprot": 198, "amino_acid": "Leu", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 198, "end_pos": 198, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7HDF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5#function" }, { "id": "A0A9J7HDF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF5" }, { "id": "PIRSR611778-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR611778-2" } ], "binding_site_uniprot": 299, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 299, "end_pos": 299, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "G3HNK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HNK4#function" }, { "id": "G3HNK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HNK4" }, { "id": "PIRSR611778-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR611778-2" } ], "binding_site_uniprot": 73, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 73, "end_pos": 73, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 615 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 338, "end_pos": 340 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 448, "end_pos": 450 }, { "start_pos": 457, "end_pos": 459 }, { "start_pos": 47, "end_pos": 49 }, { "start_pos": 668, "end_pos": 670 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HE97-1", "uniprot_ac": "A0A9J7HE97", "uniprot_id": "A0A9J7HE97_CRIGR", "mass": { "chemical_mass": 66257.0, "monoisotopic_mass": 66257.0 }, "refseq": { "ac": "XP_035308783", "name": "TOX high mobility group box family member 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308783" }, "gene_names": [ { "name": "Tox4", "type": "recommended", "evidence": [ { "id": "A0A9J7HE97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97" } ] }, { "name": "Tox4", "type": "synonym", "evidence": [ { "id": "XP_035308783", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308783" } ] } ], "protein_names": [ { "name": "TOX high mobility group box family member 4", "type": "recommended", "evidence": [ { "id": "A0A9J7HE97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97/entry#names_and_taxonomy" } ] }, { "name": "TOX high mobility group box family member 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035308783", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308783" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308783", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308783" } ] }, { "annotation": "Transcription factor that modulates cell fate reprogramming from the somatic state to the pluripotent and neuronal fate. In liver, controls the expression of hormone-regulated gluconeogenic genes such as G6PC1 and PCK1. This regulation is independent of the insulin receptor activation. Also acts as a regulatory component of protein phosphatase 1 (PP1) complexes. Component of the PNUTS-PP1 protein phosphatase complex, a PP1 complex that regulates RNA polymerase II transcription pause-release. PNUTS-PP1 also plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.", "evidence": [ { "database": "UniProtKB", "id": "G3HWS2", "url": "https://www.uniprot.org/uniprotkb/G3HWS2#function" }, { "database": "UniProtKB", "id": "ARBA00093329", "url": "https://www.uniprot.org/uniprotkb/ARBA00093329#function" }, { "database": "UniProtKB", "id": "A0A9J7HE97", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE97", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tox4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97", "locus": {} } ], "crossref": [ { "id": "A0A9J7HE97", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HE97", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21995", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21995", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774603", "url": "https://www.ncbi.nlm.nih.gov/gene/100774603", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774603", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774603", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FLSGAEX", "url": "https://omabrowser.org/oma/group/FLSGAEX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7HE97", "url": "https://www.orthodb.org/?gene=A0A9J7HE97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45781", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45781", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45781:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45781:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308783", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308783", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HE97", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HE97-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HWS2", "url": "https://www.uniprot.org/uniprotkb/G3HWS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HWS2-1", "url": "https://www.uniprot.org/uniprotkb/G3HWS2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEFPGGNDNYLTITGPSHPFLSGAETFHTPSLGDEEFEIPPISLDSDPSLAVSDVVGHFDDLADPSSSQDGSFAAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTMDLDHSIGTQYSANPPVTIDVPMTDMTSGLMGHSQLTTIDQSELSSQLGLSLGGSTILPPAQSPEDRLSTTPSPTNSLHEDGVDDFRRVRQLPSQKTVVVETGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPVPQSQTPSPPPVTTADPASPAPASTESPALSPCIVVNSTLSSYVANQASSGAGGQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVTRSVLQAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQSKVVPPPTLKMQTALIPPAVESSPEQPLNCSPEAHTAEATSPETICEMITDVVPEVESPSQMDVELVSGSPVTLSPQPRCVRSGCENPPVISKDWDNEYCSNECVVKHCRDVFLAWVASRNPNSVVFVK", "length": 621, "header": "tr|A0A9J7HE97-1|A0A9J7HE97_CRIGR Isoform 1 of TOX high mobility group box family member 4 OS=Cricetulus griseus OX=10029 GN=Tox4 PE=4 SV=1 CANONICAL=A0A9J7HE97-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HE97-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97/entry#A0A9J7HE97-1", "sequence": { "sequence": "MEFPGGNDNYLTITGPSHPFLSGAETFHTPSLGDEEFEIPPISLDSDPSLAVSDVVGHFDDLADPSSSQDGSFAAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTMDLDHSIGTQYSANPPVTIDVPMTDMTSGLMGHSQLTTIDQSELSSQLGLSLGGSTILPPAQSPEDRLSTTPSPTNSLHEDGVDDFRRVRQLPSQKTVVVETGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPVPQSQTPSPPPVTTADPASPAPASTESPALSPCIVVNSTLSSYVANQASSGAGGQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVTRSVLQAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQSKVVPPPTLKMQTALIPPAVESSPEQPLNCSPEAHTAEATSPETICEMITDVVPEVESPSQMDVELVSGSPVTLSPQPRCVRSGCENPPVISKDWDNEYCSNECVVKHCRDVFLAWVASRNPNSVVFVK", "length": 621, "header": "tr|A0A9J7HE97-1|A0A9J7HE97_CRIGR Isoform 1 of TOX high mobility group box family member 4 OS=Cricetulus griseus OX=10029 GN=Tox4 PE=4 SV=1 CANONICAL=A0A9J7HE97-1" }, "locus": {} }, { "isoform_ac": "G3HWS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97/entry#G3HWS2-1", "sequence": { "sequence": "MEFPGGNDNYLTITGPSHPFLSGAETFHTPSLGDEEFEIPPISLDSDPSLAVSDVVGHFDDLADPSSSQDGSFAAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTMDLDHSIGTQYSANPPVTIDVPMTDMTSGLMGHSQLTTIDQSELSSQLGLSLGGSTILPPAQSPEDRLSTTPSPTNSLHEDGVDDFRRQLPSQKTVVVETGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPVPQSQTPSPPPVTTADPASPAPASTESPALSPCIVVNSTLSSYVANQASSGAGGQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVTRSVLQAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQSKVVPPPTLKMQTALIPPAVESSPEQPLNCSPEAHTAEATSPETICEMITDVVPEVESPSQMDVELVSGSPVTLSPQPRCVRSGCENPPVISKDWDNEYCSNECVVKHCRDVFLAWVASRNPNSVVFVK", "length": 619, "header": "tr|G3HWS2-1|A0A9J7HE97_CRIGR Computationally mapped isoform of TOX high mobility group box family member 4 OS=Cricetulus griseus OX=10029 GN=Tox4 PE=4 SV=1 CANONICAL=A0A9J7HE97-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HWS2", "url": "https://www.uniprot.org/uniprotkb/G3HWS2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HWS2", "url": "https://www.uniprot.org/uniprotkb/G3HWS2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774603", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774603", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LAV9-1", "protein_name": "TOX high mobility group box family member 4", "gene_name": "TOX4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEFPGGSDNYLTITGPSHPFLSGAETFHTPSLGDEEFEIPPISLDSDPSLAVSDVVGHFDDLADPSSSQDGSFSAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTMDLDHSIGTQYSANPPVTIDVPMTDMTSGLMGHSQLTTIDQSELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPTSSLHEDGVEEFRRQLPSQKTVVVEAGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPAPPSQTPSPPPVATTADPASPAPATTEPPALSPSIVVNSTLSSYVTNQASSGAGGQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVTRSVLQAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKFRINLQQQPPPLQVKIVPPPTLKMQTTLVPPPVENSPEQPMNSSPEAHTVEETSPETICEMITDVVPEVESPPQMDVELVDESPVTLSPQPRCVRSGCENPPVVSKDWDNEYCSNECVVKHCRDVFLAWVASRNSNTVVFVK", "length": 620 }, "evidence": [ { "id": "A0A9J7HE97", "url": "https://omabrowser.org/oma/group/A0A9J7HE97/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O94842-1", "protein_name": "TOX high mobility group box family member 4", "gene_name": "TOX4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEFPGGNDNYLTITGPSHPFLSGAETFHTPSLGDEEFEIPPISLDSDPSLAVSDVVGHFDDLADPSSSQDGSFSAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTMDLDHSIGTQYSANPPVTIDVPMTDMTSGLMGHSQLTTIDQSELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPTSSLHEDGVEDFRRQLPSQKTVVVEAGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPAPPSQTPSPPPMATVDPASPAPASIEPPALSPSIVVNSTLSSYVANQASSGAGGQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVTRSVLQAAAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQIKSVPLPTLKMQTTLVPPTVESSPERPMNNSPEAHTVEAPSPETICEMITDVVPEVESPSQMDVELVSGSPVALSPQPRCVRSGCENPPIVSKDWDNEYCSNECVVKHCRDVFLAWVASRNSNTVVFVK", "length": 621 }, "evidence": [ { "id": "A0A9J7HE97", "url": "https://omabrowser.org/oma/group/A0A9J7HE97/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0P5K4-1", "protein_name": "TOX high mobility group box family member 4", "gene_name": "TOX4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEFPGGNDNYLTITGPSHPFLSGAETFHTPSLGDEEFEIPPISLDSDPSLAVSDVVGHFDDLADPSSSQDGSFSAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTMDLDHSIGTQYSANPPVTIDVPMTDMTSGLMGHSQLTTIDQSELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPTSSLHEDGVEEFRRQPPSQKTVVVEAGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVDMDPAPPSQTPSPPPVAAADPASPAPASTEPPALSPSIVVNSTLSSYVANQASSGAGGQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVTRSVLQAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKFRINLQQQPPPLQVKIVPPPTLKMQTTLVPPPVESSPEQPVNNSPETHTVEETTPETICEMITDVVPEVESPSQMDVELVSGSPMTLSPQPRCVRSGCENPPVVSKDWDNEYCSNECVVKHCRDVFLAWVASRNSNTVVFVK", "length": 619 }, "evidence": [ { "id": "A0A9J7HE97", "url": "https://omabrowser.org/oma/group/A0A9J7HE97/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BU11-1", "protein_name": "TOX high mobility group box family member 4", "gene_name": "Tox4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEFPGGNDNYLTITGPSHPFLSGAETFHTPSLGDEEFEIPPISLDSDPSLAVSDVVGHFDDLADPSSSQDGSFSAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTMDLDHSIGTQYSANPPVTIDVPMTDMTSGLMGHSQLTTIDQSELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPTNSLHEDGVDDFRRQLPAQKTVVVETGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPVPQSQTPSPPPVTAADPASPAPASTESPALPPCIIVNSTLSSYVANQASSGPGGQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQVGQTSTATIQPSQQAQIVTRSVLQAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQSKIVPPPTLKIQTTVVPPTVESSPEQPMNSSPEAHTVEATSPETICEMIADVVPEVESPSQMDVELVSGSPVALSPQPRCVRSGCENPPVVSKDWDNEYCSNECVVKHCRDVFLAWVASRNPNSVVFVK", "length": 619 }, "evidence": [ { "id": "A0A9J7HE97", "url": "https://omabrowser.org/oma/group/A0A9J7HE97/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE97", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE97", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97" } ], "pmid": "" }, { "name": "PTW/PP1 phosphatase complex", "id": "GO:0072357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072357", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE97", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE97", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE97", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE97", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "RNA polymerase II promoter clearance", "id": "GO:0001111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001111", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE97", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE97", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE97", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HE97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE97" }, { "id": "PS50118", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMG box", "eco_id": "ECO_0000259", "start_pos": 225, "end_pos": 293, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 249, "end_pos": 251 }, { "start_pos": 346, "end_pos": 348 }, { "start_pos": 366, "end_pos": 368 }, { "start_pos": 521, "end_pos": 523 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HCE1-1", "uniprot_ac": "A0A9J7HCE1", "uniprot_id": "A0A9J7HCE1_CRIGR", "mass": { "chemical_mass": 55560.0, "monoisotopic_mass": 55560.0 }, "refseq": { "ac": "XP_035308045", "name": "dentin matrix acidic phosphoprotein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308045" }, "gene_names": [ { "name": "Dmp1", "type": "recommended", "evidence": [ { "id": "A0A9J7HCE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE1" } ] }, { "name": "Dmp1", "type": "synonym", "evidence": [ { "id": "XP_035308045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308045" } ] } ], "protein_names": [ { "name": "Dentin matrix acidic phosphoprotein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7HCE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE1/entry#names_and_taxonomy" } ] }, { "name": "dentin matrix acidic phosphoprotein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035308045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308045" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308045", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308045" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dmp1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE1", "locus": {} } ], "crossref": [ { "id": "A0A9J7HCE1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HCE1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100773494", "url": "https://www.ncbi.nlm.nih.gov/gene/100773494", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773494", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773494", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HCE1", "url": "https://www.orthodb.org/?gene=A0A9J7HCE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23400", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23400", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23400:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23400:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07263", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07263", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308045", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308045", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QHN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HEB2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HEB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEB2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTGILLMFLWGLSCALPVARHQNTESESSEEWPGDLAPSPPPPMESKHFSFPFQNSESSDESKVSSEEQTNDNPSDSTESQEDVDSDGDQYAHRPAGGLSKSVGTEADKEDDEDDSGDDTFGDEDNGPGPEWGGRSRQDSDEDSADNTQSSEDSTSQENNAKDTPSDSRDHDSEEEADSRPEAGDSTLDSESEEHWVGGGSEGESSHGDGSEFDDEGMLSDDPESSRSEQGHSRMSSARMRSKESKGDHDLTGTQDSDDSQSVEFSSSKSFRRSQVSEEDDRGELVDTSSRETQSDSTEDTTSKEESRSESQEDTTESQSQEDSTEGQDPSSESSEEDGPSQESSSESQEGVAGESRGDNPDSTSQTGDQEDSESSEENSLNSLSSSESQSTEEQADSESNESLRLSEESQESAQDGDSSSQEGLQSQSTSRESRSQESQSEQDSRSEEEGDSDSQDSSRSKDDSNSTESTSSSEEDSHPQNMEAESRKLTVDAYHNKPIGDQDDNDCQDGY", "length": 513, "header": "tr|A0A9J7HCE1-1|A0A9J7HCE1_CRIGR Isoform 1 of Dentin matrix acidic phosphoprotein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Dmp1 PE=4 SV=1 CANONICAL=A0A9J7HCE1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QHN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE1/entry#A0A8C2QHN7-1", "sequence": { "sequence": "MKTGILLMFLWGLSCALPVARHQNTESESSEEWPGDLAPSPPPPMNSESSDESKVSSEEQTNDNPSDSTESQEDVDSDGDQYAHRPAGGLSKSVGTEADKEDDEDDSGDDTFGDEDNGPGPEWGGRSRQDSDEDSADNTQSSEDSTSQENNAKDTPSDSRDHDSEEEADSRPEAGDSTLDSESEEHWVGGGSEGESSHGDGSEFDDEGMLSDDPESSRSEQGHSRMSSARMRSKESKGDHDLTGTQDSDDSQSVEFSSSKSFRRSQVSEEDDRGELVDTSSRETQSDSTEDTTSKEESRSESQEDTTESQSQEDSTEGQDPSSESSEEDGPSQESSSESQEGVAGESRGDNPDSTSQTGDQEDSESSEENSLNSLSSSESQSTEEQADSESNESLRLSEESQESAQDGDSSSQEGLQSQSTSRESRSQESQSEQDSRSEEEGDSDSQDSSRSKDDSNSTESTSSSEEDSHPQNMEAESRKLTVDAYHNKPIGDQDDNDCQDGY", "length": 503, "header": "tr|A0A8C2QHN7-1|A0A9J7HCE1_CRIGR Computationally mapped isoform of Dentin matrix acidic phosphoprotein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Dmp1 PE=4 SV=1 CANONICAL=A0A9J7HCE1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HCE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE1/entry#A0A9J7HCE1-1", "sequence": { "sequence": "MKTGILLMFLWGLSCALPVARHQNTESESSEEWPGDLAPSPPPPMESKHFSFPFQNSESSDESKVSSEEQTNDNPSDSTESQEDVDSDGDQYAHRPAGGLSKSVGTEADKEDDEDDSGDDTFGDEDNGPGPEWGGRSRQDSDEDSADNTQSSEDSTSQENNAKDTPSDSRDHDSEEEADSRPEAGDSTLDSESEEHWVGGGSEGESSHGDGSEFDDEGMLSDDPESSRSEQGHSRMSSARMRSKESKGDHDLTGTQDSDDSQSVEFSSSKSFRRSQVSEEDDRGELVDTSSRETQSDSTEDTTSKEESRSESQEDTTESQSQEDSTEGQDPSSESSEEDGPSQESSSESQEGVAGESRGDNPDSTSQTGDQEDSESSEENSLNSLSSSESQSTEEQADSESNESLRLSEESQESAQDGDSSSQEGLQSQSTSRESRSQESQSEQDSRSEEEGDSDSQDSSRSKDDSNSTESTSSSEEDSHPQNMEAESRKLTVDAYHNKPIGDQDDNDCQDGY", "length": 513, "header": "tr|A0A9J7HCE1-1|A0A9J7HCE1_CRIGR Isoform 1 of Dentin matrix acidic phosphoprotein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Dmp1 PE=4 SV=1 CANONICAL=A0A9J7HCE1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HEB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE1/entry#A0A9J7HEB2-1", "sequence": { "sequence": "MKTGILLMFLWGLSCALPVARHQNTESESSEEWPGDLAPSPPPPMTNDNPSDSTESQEDVDSDGDQYAHRPAGGLSKSVGTEADKEDDEDDSGDDTFGDEDNGPGPEWGGRSRQDSDEDSADNTQSSEDSTSQENNAKDTPSDSRDHDSEEEADSRPEAGDSTLDSESEEHWVGGGSEGESSHGDGSEFDDEGMLSDDPESSRSEQGHSRMSSARMRSKESKGDHDLTGTQDSDDSQSVEFSSSKSFRRSQVSEEDDRGELVDTSSRETQSDSTEDTTSKEESRSESQEDTTESQSQEDSTEGQDPSSESSEEDGPSQESSSESQEGVAGESRGDNPDSTSQTGDQEDSESSEENSLNSLSSSESQSTEEQADSESNESLRLSEESQESAQDGDSSSQEGLQSQSTSRESRSQESQSEQDSRSEEEGDSDSQDSSRSKDDSNSTESTSSSEEDSHPQNMEAESRKLTVDAYHNKPIGDQDDNDCQDGY", "length": 488, "header": "tr|A0A9J7HEB2-1|A0A9J7HEB2_CRIGR Computationally mapped isoform of Dentin matrix acidic phosphoprotein 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Dmp1 PE=4 SV=1 CANONICAL=A0A9J7HCE1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QHN7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHN7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027251465", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251465" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6H1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100752268", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6H1", "locus": {} } ], "crossref": [ { "id": "A0A9J7J6H1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J6H1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14086", "database": "CDD", "categories": [ "Protein 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QJ22", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ22" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QJ22", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ22" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752268", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752268", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6H1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6H1" } ], "pmid": "" }, { "name": "calcium/calmodulin-dependent protein kinase activity", "id": "GO:0004683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004683", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6H1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "organelle", "id": "GO:0043226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043226", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6H1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6H1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", 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"A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GT89-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JIF8-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7F9C4-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A8C2M7I3-1", "A0A8C2MBI9-1", "A0A9J7JQZ1-1", "A0A8C2N3I1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7GBL6-1", "A0A9J7H8W5-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7H540-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H949-1", "A0A9J7GQY0-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] } ] }, { "uniprot_ac": "A0A8C2M497", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] }, { "ec_number": "2.7.11.1", "activity": "", 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"url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] } ] }, { "uniprot_ac": "A0A8C2N457", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] } ] }, { "uniprot_ac": "A0A8C2N4W2", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] } ] 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJA4" } ] } ] }, { "uniprot_ac": "A0A8C2QKP7", "gene_name": "Nlk", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QKP7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QKP7" } ] } ] }, { "uniprot_ac": "A0A8C2QL63", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A8C2QPB0", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] } ] }, { "uniprot_ac": "A0A9J7EUQ5", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] } ] }, { "uniprot_ac": "A0A9J7EVK4", "gene_name": "Bmp2k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] } ] }, { "uniprot_ac": "A0A9J7EVN3", "gene_name": "LOC100754361", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] } ] }, { "uniprot_ac": "A0A9J7EXX8", "gene_name": "LOC113832238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] } ] }, { "uniprot_ac": "A0A9J7F0J6", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] } ] }, { "uniprot_ac": "A0A9J7F1D2", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1D2" } ] } ] }, { "uniprot_ac": "A0A9J7F2F1", "gene_name": "Prkcd", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F821", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] } ] }, { "uniprot_ac": "A0A9J7F8T0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] } ] }, { "uniprot_ac": "A0A9J7GP29", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] } ] }, { "uniprot_ac": "A0A9J7H3M5", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] } ] }, { "uniprot_ac": "A0A9J7H3N1", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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{ "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JQZ1", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] } ] }, { "uniprot_ac": "A0A9J7JRI3", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", 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This record is derived from a genomic sequence (NW_003613632.1) and transcript sequence (IACG01040542.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016836205.1. 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"https://www.uniprot.org/uniprotkb/A0A9J7EZ27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EZ31", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EZ31-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EZB2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EZB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EZM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EZM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F021", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F021", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F021-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F021-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC37", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC37-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HE91", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HE91-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J1U8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J1U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J1U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J1U8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J5Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J645", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J645", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J645-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J645-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7M2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K3S7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K3S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBL7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEV8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKSYSCHLRPSTSRPDQGTREVWESNLSNVGDSGGTKPSVFLSQPQSNNKNSLVSAAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSLVPEGRSPRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 619, "header": "tr|A0A9J7J5Z8-1|A0A9J7J5Z8_CRIGR Isoform 1 of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LV22-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A8C2LV22-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 495, "header": "tr|A0A8C2LV22-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LX47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A8C2LX47-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSAAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 518, "header": "tr|A0A8C2LX47-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EUJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7EUJ0-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 516, "header": "tr|A0A9J7EUJ0-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EUL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7EUL0-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKSYSCHLRPSTSRPDQGTREVWESNLSNVGDSGGTKPSVFLSQPQSNNKNSLVSAAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSLVPEGRSPRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENREWSCLRTASPSIPPS", "length": 558, "header": "tr|A0A9J7EUL0-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EVE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7EVE7-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKSYSCHLRPSTSRPDQGTREVWESNLSNVGDSGGTKPSVFLSQPQSNNKNSLVSAAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 581, "header": "tr|A0A9J7EVE7-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EWR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7EWR3-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSLVPEGRSPRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 533, "header": "tr|A0A9J7EWR3-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EZ27-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7EZ27-1", "sequence": { "sequence": "MPTSETSKHCVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKSYSCHLRPSTSRPDQGTREVWESNLSNVGDSGGTKPSVFLSQPQSNNKNSLVSAAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSLVPEGRSPRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 537, "header": "tr|A0A9J7EZ27-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EZ31-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7EZ31-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKPQSNNKNSLVSAAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 539, "header": "tr|A0A9J7EZ31-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EZB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7EZB2-1", "sequence": { "sequence": "MPTSETSKHCVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSAAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSLVPEGRSPRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 474, "header": "tr|A0A9J7EZB2-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EZM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7EZM3-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSAAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSLVPEGRSPRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 556, "header": "tr|A0A9J7EZM3-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F021-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7F021-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKPQSNNKNSLVSAAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSLVPEGRSPRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 577, "header": "tr|A0A9J7F021-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HA47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7HA47-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKSYSCHLRPSTSRPDQGTREVWESNLSNVGDSGGTKPSVFLSQPQSNNKNSLEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSLVPEGRSPRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 605, "header": "tr|A0A9J7HA47-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7HAS7-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKSYSCHLRPSTSRPDQGTREVWESNLSNVGDSGGTKPSVFLSQPQSNNKNSLEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 567, "header": "tr|A0A9J7HAS7-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HC37-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7HC37-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSLVPEGRSPRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 542, "header": "tr|A0A9J7HC37-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HE91-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7HE91-1", "sequence": { "sequence": "MACLQLCLPNAEIKDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKSYSCHLRPSTSRPDQGTREVWESNLSNVGDSGGTKPSVFLSQPQSNNKNSLVSAAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSLVPEGRSPRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 580, "header": "tr|A0A9J7HE91-1|A0A9J7HE91_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J1U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7J1U8-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSAAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAWCPKDGAPGTEQPPLQACSPSLLSAPQPCENRRSLRSQNN", "length": 425, "header": "tr|A0A9J7J1U8-1|A0A9J7J1U8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J5Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7J5Z8-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKSYSCHLRPSTSRPDQGTREVWESNLSNVGDSGGTKPSVFLSQPQSNNKNSLVSAAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSLVPEGRSPRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 619, "header": "tr|A0A9J7J5Z8-1|A0A9J7J5Z8_CRIGR Isoform 1 of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J645-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7J645-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSAAKSLLNKKSDGGVKSYSCHLRPSTSRPDQGTREVWESNLSNVGDSGGTKPSVFLSQPQSNNKNSLVSAAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSLVPEGRSPRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 598, "header": "tr|A0A9J7J645-1|A0A9J7J645_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J7M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7J7M2-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSLVPEGRSPRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 554, "header": "tr|A0A9J7J7M2-1|A0A9J7J7M2_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K3S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7K3S7-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 525, "header": "tr|A0A9J7K3S7-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7KBL7-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSLVPEGRSPRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 563, "header": "tr|A0A9J7KBL7-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KDV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7KDV9-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGRWLNVHYHCSGAPAAPLQ", "length": 504, "header": "tr|A0A9J7KDV9-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KEV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8/entry#A0A9J7KEV8-1", "sequence": { "sequence": "MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKSYSCHLRPSTSRPDQGTREVWESNLSNVGDSGGTKPSVFLSQPQSNNKNSLVSAAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENREWSCLRTASPSIPPS", "length": 520, "header": "tr|A0A9J7KEV8-1|A0A9J7J5Z8_CRIGR Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Cricetulus griseus OX=10029 GN=Camk2g PE=3 SV=1 CANONICAL=A0A9J7J5Z8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 177, "start_aa": "Thr", "end_pos": 177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr177", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EUJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUJ0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EUJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUJ0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763272", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763272", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8" } ], "pmid": "" }, { "name": "calcium/calmodulin-dependent protein kinase activity", "id": "GO:0004683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004683", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "organelle", "id": "GO:0043226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043226", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, 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"https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { 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"https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] } ] }, { "uniprot_ac": "A0A8C2N185", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] } ] }, { "uniprot_ac": "A0A8C2N210", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] } ] }, { "uniprot_ac": "A0A8C2N3I1", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] } ] }, { "uniprot_ac": "A0A8C2N3U2", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] } ] }, { "uniprot_ac": "A0A8C2N457", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] } ] }, { "uniprot_ac": "A0A8C2N4W2", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] } ] }, { "uniprot_ac": "A0A8C2N6L4", "gene_name": "Prkg1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N6L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L4" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8C2N6L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L4" } ] } ] }, { "uniprot_ac": "A0A8C2N756", "gene_name": "Map2k5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N756" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2N756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N756" } ] } ] }, { "uniprot_ac": "A0A8C2N9X1", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N9X1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2N9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N9X1" } ] } ] }, { "uniprot_ac": "A0A8C2QDX9", "gene_name": "Csnk1g1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] } ] }, { "uniprot_ac": "A0A8C2QEB8", "gene_name": "Bub1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEB8" } ] } ] }, { "uniprot_ac": "A0A8C2QGY5", "gene_name": "Ttbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QGY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGY5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QGY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGY5" } ] } ] }, { "uniprot_ac": "A0A8C2QH69", "gene_name": "Sgk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QH69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QH69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH69" } ] } ] }, { "uniprot_ac": "A0A8C2QHF9", "gene_name": "Lrrk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] } ] }, { "uniprot_ac": "A0A8C2QHS8", "gene_name": "Ripk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] } ] }, { "uniprot_ac": "A0A8C2QI80", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] } ] }, { "uniprot_ac": "A0A8C2QIA1", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] } ] }, { "uniprot_ac": "A0A8C2QJ34", "gene_name": "Oxsr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] } ] }, { "uniprot_ac": "A0A8C2QJA4", "gene_name": "Pak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJA4" } ] } ] }, { "uniprot_ac": "A0A8C2QKP7", "gene_name": "Nlk", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QKP7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QKP7" } ] } ] }, { "uniprot_ac": "A0A8C2QL63", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] } ] }, { "uniprot_ac": "A0A8C2QLT0", "gene_name": "Nek9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] } ] }, { "uniprot_ac": "A0A8C2QMB3", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] } ] }, { "uniprot_ac": "A0A8C2QND0", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] } ] }, { "uniprot_ac": "A0A8C2QNX2", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] } ] }, { "uniprot_ac": "A0A8C2QPB0", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] } ] }, { "uniprot_ac": "A0A9J7EUQ5", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] } ] }, { "uniprot_ac": "A0A9J7EVK4", "gene_name": "Bmp2k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] } ] }, { "uniprot_ac": "A0A9J7EVN3", "gene_name": "LOC100754361", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] } ] }, { "uniprot_ac": "A0A9J7EXX8", "gene_name": "LOC113832238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] } ] }, { "uniprot_ac": "A0A9J7F0J6", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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} ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ 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"https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] } ] }, { "uniprot_ac": "A0A9J7GP29", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] } ] }, { "uniprot_ac": "A0A9J7H3M5", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] } ] }, { "uniprot_ac": "A0A9J7H3N1", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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{ "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JQZ1", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] } ] }, { "uniprot_ac": "A0A9J7JRI3", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", 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"https://www.uniprot.org/uniprotkb/A0A9J7HC07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC07-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J200", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J200", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J200-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J200-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J498", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J498", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J498-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J498-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J650", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J650-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J655", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J655", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J655-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J655-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J697", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J697", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J697-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J697-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPGPSWLLSPDASQAWRKEVRLSMDQEEPSPPAPAENEVKYDTNNNEEEEGELFDFDSGDEVPEADRQAPSAREATGAEAGAAGETTSPAGNGTEAEPAPEAEPAKLAVPTRVNPYSVIDITPFQEDQPPSPDANTEEEGVGLRVPSGYSVPVPCGYAVPSNLPLLLPAYSSPVIIRAESVEEEEAAEVSGDGQCNSLSSEDLPNSGDQGSQEGNALTRWAADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGDEGGNSSLEYGWSSSEFESYEEQSDSECKNGIPRSFLRSSHKKQLSHDLTRFKAHCEEKMRGLVASTVGAMEVPQAKHRQERKMQKLMKAAKEGTKDGLEKTKAAVKRGRSFIRTKSLISQDHRYCFEEEQNLFIDVDCKHPEAVLTPMPEGLSQQQVVRRYILGSIVESEKNYVDALRRILEQYEKPLSEMEPRLLSDRKLKMVFYRVKEILQCHSMFQIALASRVSEWDAVETIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCAAKPAFLEFLKLSQDSSPDRVTLHSLMMRPIQRFPQFILLLQDMLKNTAKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEVKQIAKAINERYLNKLLSSGNRYLIRSDDVIETVYNDRGEIIKTKERRLFMLNDVLMCATASSRTSHESHAVMSQRYLLKWSVPLGHVDVIEYGGGSGTGEHSRHHVAHSPESLAVMANVKPPLQHAIWKASAGWISERCSFQWALQFNEVDIVLRVNLLEARDEPSAESYKVYMGPGQLYQDLQNLLHDLNVVGQISQLIGNLRGSYQNLSQSVAHDWTSGLHRLILKKEEEIRAADRCRIHLQLPGKQDKSGRPTFFTAVFNTFTSAIKESWVSSLQLAKLALEEENHMGWFCVDDDGNLAKKETHPLLVGHMPVMVARQPEFKIECAAYNPEPYLSNESQPASPSTARGFLWIGSCSNQMGQVAIVSFQSSNPKVIECFNVESRILCMVYIPAEEPKPQESNDATDPDATASRASHVPTICLGTEEGSISIYKSSQGCKKVRLQHFYTPDKSTVMSLACSPQGLYAGLVNGSVASYTKAPDGSWNSEPQQVIKLGVLPVRSLLLVEGALWAASGGQVFMASLETHTIENQLEAHQDEGMVISHMAVAGVGIWIAFTSGSTLRLFHTETLKHLQDVNIDAPVHSMLPGHQRLSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGMVSYHAHNGPVKFIVMATAFQKNKDRARDSPPSGPEPQDEDPKDLLCGEEGTSCLGQTDTNTAANTAVWLGDSPGLTAQKSDLSSSSGSLSLSHGSSSLEHRSVDNSLCDLLKDPSASPRSRAQRSRRAKASSALVVCGGQGHRRVHRKARQPSQEDLVSSVMVWQIPLLSM", "length": 1422, "header": "tr|A0A9J7J650-1|A0A9J7J650_CRIGR Isoform 1 of Rho guanine nucleotide exchange factor 10 OS=Cricetulus griseus OX=10029 GN=Arhgef10 PE=4 SV=1 CANONICAL=A0A9J7J650-1" }, "isoforms": [ { "isoform_ac": "A0A9J7EUT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650/entry#A0A9J7EUT8-1", "sequence": { "sequence": "MAPGPSWLLSPDASQAWRKEVRLSMDQEEPSPPAPAENEVKYDTNNNEEEEGELFDFDSGDEVPEADRQAPSAREATGAEAGAAGETTSPAGNGTEAEPAPEAEPAKLAVPTRVNPYSVIDITPFQEDQPPSPDANTEEEGVGLRVPSGYSVPVPCGYAVPSNLPLLLPAYSSPVIIRAESVEEEEAAEVSGDGQCNSLSSEDLPNSGDQGSQEGNALTRWAADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGDEGGNSSLEYGWSSSEFESYEEQSDSECKNGIPRSFLRSSHKKQLSHDLTRFKAHCEEKMRGLVASTVGAMEVPQAKHRQERKMQKLMKAAKEGTKDGLEKTKAAVKRGRSFIRTKSLISQDHRYCFEEEQNLFIDVDCKHPEAVLTPMPEGLSQQQVVRRYILGSIVESEKNYVDALRRILEQYEKPLSEMEPRLLSDRKLKMVFYRVKEILQCHSMFQIALASRVSEWDAVETIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCAAKPAFLEFLKLSQDSSPDRVTLHSLMMRPIQRFPQFILLLQDMLKNTAKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEVKQIAKAINERYLNKLLSSGNRYLIRSDDVIETVYNDRGEIIKTKERRLFMLNDVLMCATASSRTSHESHAVMSQRYLLKWSVPLGHVDVIEYGGGSGTGEHSRHHVAHSPESLAVMANVKPHKVYMGPGQLYQDLQNLLHDLNVVGQISQLIGNLRGSYQNLSQSVAHDWTSGLHRLILKKEEEIRAADRCRIHLQLPGKQDKSGRPTFFTAVFNTFTSAIKESWVSSLQLAKLALEEENHMGWFCVDDDGNLAKKETHPLLVGHMPVMVARQPEFKIECAAYNPEPYLSNESQPASPSTARGFLWIGSCSNQMGQVAIVSFQSSNPKVIECFNVESRILCMVYIPAEEPKPQESNDATDPDATASRASHVPTICLGTEEGSISIYKSSQGCKKVRLQHFYTPDKSTVMSLACSPQGLYAGLVNGSVASYTKAPDGSWNSEPQQVIKLGVLPVRSLLLVEGALWAASGGQVFMASLETHTIENQLEAHQDEGMVISHMAVAGVGIWIAFTSGSTLRLFHTETLKHLQDVNIDAPVHSMLPGHQRLSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGMVSYHAHNGPVKFIVMATAFQKNKDRARDSPPSGPEPQDEDPKDLLCGEEGTSCLGQTDTNTAANTAVWLGDSPGLTAQKSDLSSSSGSLSLSHGSSSLEHRSVDNSLCDLLKDPSASPRSRAQRSRRAKASSALVVCGGQGHRRVHRKARQPSQEDLVSSVMVWQIPLLSM", "length": 1374, "header": "tr|A0A9J7EUT8-1|A0A9J7J650_CRIGR Computationally mapped isoform of Rho guanine nucleotide exchange factor 10 OS=Cricetulus griseus OX=10029 GN=Arhgef10 PE=4 SV=1 CANONICAL=A0A9J7J650-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EX15-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650/entry#A0A9J7EX15-1", "sequence": { "sequence": "MAPGPSWLLSPDASQAWRKEVRLSMDQEEPSPPAPAENEVKYDTNNNEEEEGELFDFDSGDEVPEADRQAPSAREATGAEAGAAGETTSPAGNGTEAEPAPEAEPAKLAVPTRVNPYSVIDITPFQEDQPPSPDANTEEEGVGLRVPSGYSVPVPCGYAVPSNLPLLLPAYSSPVIIRAESVEEEEAAEVSGDGQCNSLSSEDLPNSGDQGSQEGNALTRWAADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGDEGGNSSLEYGWSSSEFESYEEQSDSECKNGIPRSFLRSSHKKQLSHDLTRFKAHCEEKMRGLVASTVGAMEVPQAKHRQERKMQKLMKAAKEGTKDGLEKTKAAVKRGRSFIRTKSLISQDHRYCFEEEQNLFIDVDCKHPEAVLTPMPEGLSQQQVVRRYILGSIVESEKNYVDALRRILEQYEKPLSEMEPRLLSDRKLKMVFYRVKEILQCHSMFQIALASRVSEWDAVETIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCAAKPAFLEFLKLSQDSSPDRVTLHSLMMRPIQRFPQFILLLQDMLKNTAKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEVKQIAKAINERYLNKLLSSGNRYLIRSDDVIETVYNDRGEIIKTKERRLFMLNDVLMCATASSRTSHESHAVMSQRYLLKWSVPLGHVDVIEYGGGSGTGEHSRHHVAHSPESLAVMANVKPPLQHAIWKASAGWISERCSFQWALQFNEVDIVLRVNLLEARDEPSAESYKVYMGPGQLYQDLQNLLHDLNVVGQISQLIGNLRGSYQNLSQSVAHDWTSGLHRLILKKEEEIRAADRCRIHLQLPGKQDKSGRPTFFTAVFNTFTSAIKESWVSSLQLAKLALEEENHMGWFCVDDDGNLAKKETHPLLVGHMPVMVARQPEFKIGSCSNQMGQVAIVSFQSSNPKVIECFNVESRILCMVYIPAEEPKPQESNDATDPDATASRASHVPTICLGTEEGSISIYKSSQGCKKVRLQHFYTPDKSTVMSLACSPQGLYAGLVNGSVASYTKAPDGSWNSEPQQVIKLGVLPVRSLLLVEGALWAASGGQVFMASLETHTIENQLEAHQDEGMVISHMAVAGVGIWIAFTSGSTLRLFHTETLKHLQDVNIDAPVHSMLPGHQRLSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGMVSYHAHNGPVKFIVMATAFQKNKDRARDSPPSGPEPQDEDPKDLLCGEEGTSCLGQTDTNTAANTAVWLGDSPGLTAQKSDLSSSSGSLSLSHGSSSLEHRSVDNSLCDLLKDPSASPRSRAQRSRRAKASSALVVCGGQGHRRVHRKARQPSQEDLVSSVMVWQIPLLSM", "length": 1393, "header": "tr|A0A9J7EX15-1|A0A9J7J650_CRIGR Computationally mapped isoform of Rho guanine nucleotide exchange factor 10 OS=Cricetulus griseus OX=10029 GN=Arhgef10 PE=4 SV=1 CANONICAL=A0A9J7J650-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F0H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650/entry#A0A9J7F0H3-1", "sequence": { "sequence": "MAPGPSWLLSPDASQAWRKEVRLSMDQEEPSPPAPAENEVKYDTNNNEEEEGELFDFDSGDEVPEADRQAPSAREATGAEAGAAGETTSPAGNGTEAEPAPEAEPAKLAVPTRVNPYSVIDITPFQEDQPPSPDANTEEEGVGLRVPSGYSVPVPCGYAVPSNLPLLLPAYSSPVIIRAESVEEEEAAEVSGDGQCNSLSSEDLPNSGDQGSQEGNALTRWAADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGDEGGNSSLEYGWSSSEFESYEEQSDSECKNGIPRSFLRSSHKKQMQKLMKAAKEGTKDGLEKTKAAVKRGRSFIRTKSLISQDHRYCFEEEQNLFIDVDCKHPEAVLTPMPEGLSQQQVVRRYILGSIVESEKNYVDALRRILEQYEKPLSEMEPRLLSDRKLKMVFYRVKEILQCHSMFQIALASRVSEWDAVETIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCAAKPAFLEFLKLSQDSSPDRVTLHSLMMRPIQRFPQFILLLQDMLKNTAKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEVKQIAKAINERYLNKLLSSGNRYLIRSDDVIETVYNDRGEIIKTKERRLFMLNDVLMCATASSRTSHESHAVMSQRYLLKWSVPLGHVDVIEYGGGSGTGEHSRHHVAHSPESLAVMANVKPPLQHAIWKASAGWISERCSFQWALQFNEVDIVLRVNLLEARDEPSAESYKVYMGPGQLYQDLQNLLHDLNVVGQISQLIGNLRGSYQNLSQSVAHDWTSGLHRLILKKEEEIRAADRCRIHLQLPGKQDKSGRPTFFTAVFNTFTSAIKESWVSSLQLAKLALEEENHMGWFCVDDDGNLAKKETHPLLVGHMPVMVARQPEFKIECAAYNPEPYLSNESQPASPSTARGFLWIGSCSNQMGQVAIVSFQSSNPKVIECFNVESRILCMVYIPAEEPKPQESNDATDPDATASRASHVPTICLGTEEGSISIYKSSQGCKKVRLQHFYTPDKSTVMSLACSPQGLYAGLVNGSVASYTKAPDGSWNSEPQQVIKLGVLPVRSLLLVEGALWAASGGQVFMASLETHTIENQLEAHQDEGMVISHMAVAGVGIWIAFTSGSTLRLFHTETLKHLQDVNIDAPVHSMLPGHQRLSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGMVSYHAHNGPVKFIVMATAFQKNKDRARDSPPSGPEPQDEDPKDLLCGEEGTSCLGQTDTNTAANTAVWLGDSPGLTAQKSDLSSSSGSLSLSHGSSSLEHRSVDNSLCDLLKDPSASPRSRAQRSRRAKASSALVVCGGQGHRRVHRKARQPSQEDLVSSVMVWQIPLLSM", "length": 1383, "header": "tr|A0A9J7F0H3-1|A0A9J7J650_CRIGR Computationally mapped isoform of Rho guanine nucleotide exchange factor 10 OS=Cricetulus griseus OX=10029 GN=Arhgef10 PE=4 SV=1 CANONICAL=A0A9J7J650-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HC07-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650/entry#A0A9J7HC07-1", "sequence": { "sequence": "MDQEEPSPPAPAGNGTEAEPAPEAEPAKLAVPTRVNPYSVIDITPFQEDQPPSPDANTEEEGVGLRVPSGYSVPVPCGYAVPSNLPLLLPAYSSPVIIRAESVEEEEAAEVSGDGQCNSLSSEDLPNSGDQGSQEGNALTRWAADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGDEGGNSSLEYGWSSSEFESYEEQSDSECKNGIPRSFLRSSHKKQLSHDLTRFKAHCEEKMRGLVASTVGAMEVPQAKHRQERKMQKLMKAAKEGTKDGLEKTKAAVKRGRSFIRTKSLISQDHRYCFEEEQNLFIDVDCKHPEAVLTPMPEGLSQQQVVRRYILGSIVESEKNYVDALRRILEQYEKPLSEMEPRLLSDRKLKMVFYRVKEILQCHSMFQIALASRVSEWDAVETIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCAAKPAFLEFLKLSQDSSPDRVTLHSLMMRPIQRFPQFILLLQDMLKNTAKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEVKQIAKAINERYLNKLLSSGNRYLIRSDDVIETVYNDRGEIIKTKERRLFMLNDVLMCATASSRTSHESHAVMSQRYLLKWSVPLGHVDVIEYGGGSGTGEHSRHHVAHSPESLAVMANVKPPLQHAIWKASAGWISERCSFQWALQFNEVDIVLRVNLLEARDEPSAESYKVYMGPGQLYQDLQNLLHDLNVVGQISQLIGNLRGSYQNLSQSVAHDWTSGLHRLILKKEEEIRAADRCRIHLQLPGKQDKSGRPTFFTAVFNTFTSAIKESWVSSLQLAKLALEEENHMGWFCVDDDGNLAKKETHPLLVGHMPVMVARQPEFKIECAAYNPEPYLSNESQPASPSTARGFLWIGSCSNQMGQVAIVSFQSSNPKVIECFNVESRILCMVYIPAEEPKPQESNDATDPDATASRASHVPTICLGTEEGSISIYKSSQGCKKVRLQHFYTPDKSTVMSLACSPQGLYAGLVNGSVASYTKAPDGSWNSEPQQVIKLGVLPVRSLLLVEGALWAASGGQVFMASLETHTIENQLEAHQDEGMVISHMAVAGVGIWIAFTSGSTLRLFHTETLKHLQDVNIDAPVHSMLPGHQRLSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGMVSYHAHNGPVKFIVMATAFQKNKDRARDSPPSGPEPQDEDPKDLLCGEEGTSCLGQTDTNTAANTAVWLGDSPGLTAQKSDLSSSSGSLSLSHGSSSLEHRSVDNSLCDLLKDPSASPRSRAQRSRRAKASSALVVCGGQGHRRVHRKARQPSQEDLVSSVMVWQIPLLSM", "length": 1343, "header": "tr|A0A9J7HC07-1|A0A9J7J650_CRIGR Computationally mapped isoform of Rho guanine nucleotide exchange factor 10 OS=Cricetulus griseus OX=10029 GN=Arhgef10 PE=4 SV=1 CANONICAL=A0A9J7J650-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J200-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650/entry#A0A9J7J200-1", "sequence": { "sequence": "MAPGPSWLLSPDASQAWRKEVRLSMDQEEPSPPAPAENEVKYDTNNNEEEEGELFDFDSGDEVPEADRQAPSAREATGAEAGAAGETTSPAGNGTEAEPAPEAEPAKLAVPTRVNPYSVIDITPFQEDQPPSPDANTEEEGVGLRVPSGYSVPVPCGYAVPSNLPLLLPAYSSPVIIRAESVEEEEAAEVSGDGQCNSLSSEDLPNSGDQGSQEGNALTRWAADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGDEGGNSSLEYGWSSSEFESYEEQSDSECKNGIPRSFLRSSHKKQMQKLMKAAKEGTKDGLEKTKAAVKRGRSFIRTKSLISQDHRYCFEEEQNLFIDVDCKHPEAVLTPMPEGLSQQQVVRRYILGSIVESEKNYVDALRRILEQYEKPLSEMEPRLLSDRKLKMVFYRVKEILQCHSMFQIALASRVSEWDAVETIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCAAKPAFLEFLKLSQDSSPDRVTLHSLMMRPIQRFPQFILLLQDMLKNTAKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEVKQIAKAINERYLNKLLSSGNRYLIRSDDVIETVYNDRGEIIKTKERRLFMLNDVLMCATASSRTSHESHAVMSQRYLLKWSVPLGHVDVIEYGGGSGTGEHSRHHVAHSPESLAVMANVKPHKVYMGPGQLYQDLQNLLHDLNVVGQISQLIGNLRGSYQNLSQSVAHDWTSGLHRLILKKEEEIRAADRCRIHLQLPGKQDKSGRPTFFTAVFNTFTSAIKESWVSSLQLAKLALEEENHMGWFCVDDDGNLAKKETHPLLVGHMPVMVARQPEFKIECAAYNPEPYLSNESQPASPSTARGFLWIGSCSNQMGQVAIVSFQSSNPKVIECFNVESRILCMVYIPAEEPKPQESNDATDPDATASRASHVPTICLGTEEGSISIYKSSQGCKKVRLQHFYTPDKSTVMSLACSPQGLYAGLVNGSVASYTKAPDGSWNSEPQQVIKLGVLPVRSLLLVEGALWAASGGQVFMASLETHTIENQLEAHQDEGMVISHMAVAGVGIWIAFTSGSTLRLFHTETLKHLQDVNIDAPVHSMLPGHQRLSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGMVSYHAHNGPVKFIVMATAFQKNKDRARDSPPSGPEPQDEDPKDLLCGEEGTSCLGQTDTNTAANTAVWLGDSPGLTAQKSDLSSSSGSLSLSHGSSSLEHRSVDNSLCDLLKDPSASPRSRAQRSRRAKASSALVVCGGQGHRRVHRKARQPSQEDLVSSVMVWQIPLLSM", "length": 1335, "header": "tr|A0A9J7J200-1|A0A9J7J200_CRIGR Computationally mapped isoform of Rho guanine nucleotide exchange factor 10 OS=Cricetulus griseus OX=10029 GN=Arhgef10 PE=4 SV=1 CANONICAL=A0A9J7J650-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J498-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650/entry#A0A9J7J498-1", "sequence": { "sequence": "MAPGPSWLLSPDASQAWRKEVRLSMDQEEPSPPAPAGNGTEAEPAPEAEPAKLAVPTRVNPYSVIDITPFQEDQPPSPDANTEEEGVGLRVPSGYSVPVPCGYAVPSNLPLLLPAYSSPVIIRAESVEEEEAAEVSGDGQCNSLSSEDLPNSGDQGSQEGNALTRWAADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGDEGGNSSLEYGWSSSEFESYEEQSDSECKNGIPRSFLRSSHKKQLSHDLTRFKAHCEEKMRGLVASTVGAMEVPQAKHRQERKMQKLMKAAKEGTKDGLEKTKAAVKRGRSFIRTKSLISQDHRYCFEEEQNLFIDVDCKHPEAVLTPMPEGLSQQQVVRRYILGSIVESEKNYVDALRRILEQYEKPLSEMEPRLLSDRKLKMVFYRVKEILQCHSMFQIALASRVSEWDAVETIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCAAKPAFLEFLKLSQDSSPDRVTLHSLMMRPIQRFPQFILLLQDMLKNTAKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEVKQIAKAINERYLNKLLSSGNRYLIRSDDVIETVYNDRGEIIKTKERRLFMLNDVLMCATASSRTSHESHAVMSQRYLLKWSVPLGHVDVIEYGGGSGTGEHSRHHVAHSPESLAVMANVKPPLQHAIWKASAGWISERCSFQWALQFNEVDIVLRVNLLEARDEPSAESYKVYMGPGQLYQDLQNLLHDLNVVGQISQLIGNLRGSYQNLSQSVAHDWTSGLHRLILKKEEEIRAADRCRIHLQLPGKQDKSGRPTFFTAVFNTFTSAIKESWVSSLQLAKLALEEENHMGWFCVDDDGNLAKKETHPLLVGHMPVMVARQPEFKIECAAYNPEPYLSNESQPASPSTARGFLWIGSCSNQMGQVAIVSFQSSNPKVIECFNVESRILCMVYIPAEEPKPQESNDATDPDATASRASHVPTICLGTEEGSISIYKSSQGCKKVRLQHFYTPDKSTVMSLACSPQGLYAGLVNGSVASYTKAPDGSWNSEPQQVIKLGVLPVRSLLLVEGALWAASGGQVFMASLETHTIENQLEAHQDEGMVISHMAVAGVGIWIAFTSGSTLRLFHTETLKHLQDVNIDAPVHSMLPGHQRLSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGMVSYHAHNGPVKFIVMATAFQKNKDRARDSPPSGPEPQDEDPKDLLCGEEGTSCLGQTDTNTAANTAVWLGDSPGLTAQKSDLSSSSGSLSLSHGSSSLEHRSVDNSLCDLLKDPSASPRSRAQRSRRAKASSALVVCGGQGHRRVHRKARQPSQEDLVSSVMVWQIPLLSM", "length": 1367, "header": "tr|A0A9J7J498-1|A0A9J7J498_CRIGR Computationally mapped isoform of Rho guanine nucleotide exchange factor 10 OS=Cricetulus griseus OX=10029 GN=Arhgef10 PE=4 SV=1 CANONICAL=A0A9J7J650-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J650-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650/entry#A0A9J7J650-1", "sequence": { "sequence": 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"length": 1422, "header": "tr|A0A9J7J650-1|A0A9J7J650_CRIGR Isoform 1 of Rho guanine nucleotide exchange factor 10 OS=Cricetulus griseus OX=10029 GN=Arhgef10 PE=4 SV=1 CANONICAL=A0A9J7J650-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J655-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650/entry#A0A9J7J655-1", "sequence": { "sequence": "MAPGPSWLLSPDASQAWRKEVRLSMDQEEPSPPAPAENEVKYDTNNNEEEEGELFDFDSGDEVPEADRQAPSAREATGAEAGAAGETTSPAGNGTEAEPAPEAEPAKLAVPTRVNPYSVIDITPFQEDQPPSPDANTEEEGVGLRVPSGYSVPVPCGYAVPSNLPLLLPAYSSPVIIRAESVEEEEAAEVSGDGQCNSLSSEDLPNSGDQGSQEGNALTRWAADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGDEGGNSSLEYGWSSSEFESYEEQSDSECKNGIPRSFLRSSHKKQLSHDLTRFKAHCEEKMRGLVASTVGAMEVPQAKHRQERKMQKLMKAAKEGTKDGLEKTKAAVKRGRSFIRTKSLISQDHRYCFEEEQNLFIDVDCKHPEAVLTPMPEGLSQQQVVRRYILGSIVESEKNYVDALRRILEQYEKPLSEMEPRLLSDRKLKMVFYRVKEILQCHSMFQIALASRVSEWDAVETIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCAAKPAFLEFLKLSQDSSPDRVTLHSLMMRPIQRFPQFILLLQDMLKNTAKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEVKQIAKAINERYLNKLLSSGNRYLIRSDDVIETVYNDRGEIIKTKERRLFMLNDVLMCATASSRTSHESHAVMSQRYLLKWSVPLGHVDVIEYGGGSGTGEHSRHHVAHSPESLAVMANVKPPLQHAIWKASAGWISERCSFQWALQFNEVDIVLRVNLLEARDEPSAESYKVYMGPGQLYQDLQNLLHDLNVVGQISQLIGNLRGSYQNLSQSVAHDWTSGLHRLILKKEEEIRAADRCRIHLQLPGKQDKSGRPTFFTAVFNTFTSAIKESWVSSLQLAKLALEEENHMGWFCVDDDGNLAKKETHPLLVGHMPVMVARQPEFKIECAAYNPEPYLSNESQPASPSTARGFLWIGSCSNQMGQVAIVSFQSSNPKVIECFNVESRILCMVYIPAEEPKPQESNDATDPDATASRASHVPTICLGTEEGSISIYKSSQGCKKVRLQHFYTPDKSTVMSLACSPQGLYAGLVNGSVASYTKAPDGSWNSEPQQVIKLGVLPVRSLLLVEGALWAASGGQVFMASLETHTIEEESGT", "length": 1153, "header": "tr|A0A9J7J655-1|A0A9J7J655_CRIGR Computationally mapped isoform of Rho guanine nucleotide exchange factor 10 isoform X14 OS=Cricetulus griseus OX=10029 GN=Arhgef10 PE=4 SV=1 CANONICAL=A0A9J7J650-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J697-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650/entry#A0A9J7J697-1", "sequence": { "sequence": "MDQEEPSPPAPAENEVKYDTNNNEEEEGELFDFDSGDEVPEADRQAPSAREATGAEAGAAGETTSPAGNGTEAEPAPEAEPAKLAVPTRVNPYSVIDITPFQEDQPPSPDANTEEEGVGLRVPSGYSVPVPCGYAVPSNLPLLLPAYSSPVIIRAESVEEEEAAEVSGDGQCNSLSSEDLPNSGDQGSQEGNALTRWAADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGDEGGNSSLEYGWSSSEFESYEEQSDSECKNGIPRSFLRSSHKKQLSHDLTRFKAHCEEKMRGLVASTVGAMEVPQAKHRQERKMQKLMKAAKEGTKDGLEKTKAAVKRGRSFIRTKSLISQDHRYCFEEEQNLFIDVDCKHPEAVLTPMPEGLSQQQVVRRYILGSIVESEKNYVDALRRILEQYEKPLSEMEPRLLSDRKLKMVFYRVKEILQCHSMFQIALASRVSEWDAVETIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCAAKPAFLEFLKLSQDSSPDRVTLHSLMMRPIQRFPQFILLLQDMLKNTAKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEVKQIAKAINERYLNKLLSSGNRYLIRSDDVIETVYNDRGEIIKTKERRLFMLNDVLMCATASSRTSHESHAVMSQRYLLKWSVPLGHVDVIEYGGGSGTGEHSRHHVAHSPESLAVMANVKPPLQHAIWKASAGWISERCSFQWALQFNEVDIVLRVNLLEARDEPSAESYKVYMGPGQLYQDLQNLLHDLNVVGQISQLIGNLRGSYQNLSQSVAHDWTSGLHRLILKKEEEIRAADRCRIHLQLPGKQDKSGRPTFFTAVFNTFTSAIKESWVSSLQLAKLALEEENHMGWFCVDDDGNLAKKETHPLLVGHMPVMVARQPEFKIECAAYNPEPYLSNESQPASPSTARGFLWIGSCSNQMGQVAIVSFQSSNPKVIECFNVESRILCMVYIPAEEPKPQESNDATDPDATASRASHVPTICLGTEEGSISIYKSSQGCKKVRLQHFYTPDKSTVMSLACSPQGLYAGLVNGSVASYTKAPDGSWNSEPQQVIKLGVLPVRSLLLVEGALWAASGGQVFMASLETHTIENQLEAHQDEGMVISHMAVAGVGIWIAFTSGSTLRLFHTETLKHLQDVNIDAPVHSMLPGHQRLSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGMVSYHAHNGPVKFIVMATAFQKNKDRARDSPPSGPEPQDEDPKDLLCGEEGTSCLGQTDTNTAANTAVWLGDSPGLTAQKSDLSSSSGSLSLSHGSSSLEHRSVDNSLCDLLKDPSASPRSRAQRSRRAKASSALVVCGGQGHRRVHRKARQPSQEDLVSSVMVWQIPLLSM", "length": 1398, "header": "tr|A0A9J7J697-1|A0A9J7J697_CRIGR Computationally mapped isoform of Rho guanine nucleotide exchange factor 10 OS=Cricetulus griseus OX=10029 GN=Arhgef10 PE=4 SV=1 CANONICAL=A0A9J7J650-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EUT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUT8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EUT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUT8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757483", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757483", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J650", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J650", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J650", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J650", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J650", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": 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"annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J650", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J650" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 421, "end_pos": 608, "start_aa": "Val", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1090, "end_pos": 1092 }, { "start_pos": 267, "end_pos": 269 }, { "start_pos": 521, "end_pos": 523 }, { "start_pos": 827, "end_pos": 829 }, { "start_pos": 93, "end_pos": 95 }, { "start_pos": 957, "end_pos": 959 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J7W4-1", "uniprot_ac": "A0A9J7J7W4", "uniprot_id": "A0A9J7J7W4_CRIGR", "mass": { "chemical_mass": 128946.0, "monoisotopic_mass": 128946.0 }, "refseq": { "ac": "XP_027243744", "name": "reticulon-4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243744" }, "gene_names": [ { "name": "Rtn4", "type": "recommended", "evidence": [ { "id": "A0A9J7J7W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4" } ] }, { "name": "Rtn4", "type": "synonym", "evidence": [ { "id": "XP_027243744", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243744" } ] } ], "protein_names": [ { "name": "Reticulon", "type": "recommended", "evidence": [ { "id": "A0A9J7J7W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4/entry#names_and_taxonomy" } ] }, { "name": "reticulon-4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027243744", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243744" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027243744", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243744" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7W4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rtn4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4", "locus": {} } ], "crossref": [ { "id": "A0A9J7J7W4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J7W4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100764263", "url": "https://www.ncbi.nlm.nih.gov/gene/100764263", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764263", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764263", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7J7W4", "url": "https://www.orthodb.org/?gene=A0A9J7J7W4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45799", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45799", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45799:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45799:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02453", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02453", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027243744", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243744", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7EV09", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EV09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EV09-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EV09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EXA4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EXA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EZJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EZJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EZJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EZJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F0P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F0P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7W4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDLDQSPLVSSTADSPSRPPPPPAFKYQFVTEPEDEEDEEEEEDEEDEDEDLEELEVLERKPAAGLSAAPVPPAAAAPLLDLGSDSVPPAPRGPLLAAPPAAPERQPSWERSPAAPAQSLPAAAAVLPSKLPEDDEPPARPPPPPPAGVSPLAEPAAPPSTPAAPKRRGSGSVGECRGAPAPTPLPLDETLFALPAASEPVIPSSAEKSMDLKEQPGDTVPSAQEDFPSVPLETAASLPSLSPLSTVSFKEHEYLGNLSAVSSTEGTIEETLNEASKELSERATNPFVDRALTEFSELEYSEMGSSFTGSPKVESAILVENPKDEGTVRSRDKEDLVSSAALHNPLESPMTLPKVVKEDRVVSPEKTKDILNEMQVSVVAPMREEYADFKPFEQAWEVKDTYEGTRDVLAARGNLENRMDKKSFEDNLEQKSHGKDSESSNDDTSFPSTPEPVKDGSRAYITCASFTSASDSTAASIFPLLEDHASENKTDEKKIEERKAQITTDKTSPQTSNPFLVGTQDSEADYVTTDNLSKVTKEEVASMPEGLTPDLVQEACESELNEATGTKMAYETKMDLVQTSEALQESLYPTAQLCPSFEESEATPSPVLPDIVMEAPLNSLLPNAGASAAQHSVSPLGAPASASYDSSKLEPENPPPYEEAMNVAPKALGIKEEIKEPESINAAVQETEAPYISIACDLIKETKLSTEPSPDFSNYSEIAKFEKLVPDHVELVEDSSPDSEPVDLFSDDSIPEVPQTQEEAVMLMKESLAEVSEMVTQHKHEERLSASPQEVGKPYLEAFQPSLHITKDAAPNEIPALTKKEKIPLQMEELNTSIYSNDGLLTSKEDKIKESETFSDSSPIEIIDEFPAFISSKTDSSPKLAKEYTDLEISNKSEIANVQSKAGSLPCSELPHDLSFKNIHPKDEVHVSDEFSKDRSSVSKVSLLPSSISALEPRTEMGSLVKPQVLMKEAEKKLPSDTEREDRSLSALFSSELSKISVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVTVSEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGLANKSVKEAMAKIQAKIPGLKRKAE", "length": 1186, "header": "tr|A0A9J7J7W4-1|A0A9J7J7W4_CRIGR Isoform 1 of Reticulon OS=Cricetulus griseus OX=10029 GN=Rtn4 PE=4 SV=1 CANONICAL=A0A9J7J7W4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7EV09-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4/entry#A0A9J7EV09-1", "sequence": { "sequence": "MEDLDQSPLVSSTADSPSRPPPPPAFKYQFVTEPEDEEDEEEEEDEEDEDEDLEELEVLERKPAAGLSAAPVPPAAAAPLLDLGSDSVPPAPRGPLLAAPPAAPERQPSWERSPAAPAQSLPAAAAVLPSKLPEDDEPPARPPPPPPAGVSPLAEPAAPPSTPAAPKRRGSGSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVTVSEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGLANKSVKEAMAKIQAKIPGLKRKAE", "length": 362, "header": "tr|A0A9J7EV09-1|A0A9J7J7W4_CRIGR Computationally mapped isoform of Reticulon OS=Cricetulus griseus OX=10029 GN=Rtn4 PE=4 SV=1 CANONICAL=A0A9J7J7W4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EXA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4/entry#A0A9J7EXA4-1", "sequence": { "sequence": "MEDLDQSPLVSSTADSPSRPPPPPAFKYQFVTEPEDEEDEEEEEDEEDEDEDLEELEVLERKPAAGLSAAPVPPAAAAPLLDLGSDSVPPAPRGPLLAAPPAAPERQPSWERSPAAPAQSLPAAAAVLPSKLPEDDEPPARPPPPPPAGVSPLAEPAAPPSTPAAPKRRGSGSVDETLFALPAASEPVIPSSAVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVTVSEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGLANKSVKEAMAKIQAKIPGLKRKAE", "length": 381, "header": "tr|A0A9J7EXA4-1|A0A9J7J7W4_CRIGR Computationally mapped isoform of Reticulon OS=Cricetulus griseus OX=10029 GN=Rtn4 PE=4 SV=1 CANONICAL=A0A9J7J7W4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EZJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4/entry#A0A9J7EZJ5-1", "sequence": { "sequence": "MEDLDQSPLVSSTADSPSRPPPPPAFKYQFVTEPEDEEDEEEEEDEEDEDEDLEELEVLERKPAAGLSAAPVPPAAAAPLLDLGSDSVPPAPRGPLLAAPPAAPERQPSWERSPAAPAQSLPAAAAVLPSKLPEDDEPPARPPPPPPAGVSPLAEPAAPPSTPAAPKRRGSGSVGECRGAPAPTPLPLDETLFALPAASEPVIPSSAVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVTVSEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGLANKSVKEAMAKIQAKIPGLKRKAE", "length": 395, "header": "tr|A0A9J7EZJ5-1|A0A9J7J7W4_CRIGR Computationally mapped isoform of Reticulon OS=Cricetulus griseus OX=10029 GN=Rtn4 PE=4 SV=1 CANONICAL=A0A9J7J7W4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EZJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4/entry#A0A9J7EZJ9-1", "sequence": { "sequence": "MEDLDQSPLVSSTADSPSRPPPPPAFKYQFVTEPEDEEDEEEEEDEEDEDEDLEELEVLERKPAAGLSAAPVPPAAAAPLLDLGSDSVPPAPRGPLLAAPPAAPERQPSWERSPAAPAQSLPAAAAVLPSKLPEDDEPPARPPPPPPAGVSPLAEPAAPPSTPAAPKRRGSGSVDETLFALPAASEPVIPSSAEKSMDLKEQPGDTVPSAQEDFPSVPLETAASLPSLSPLSTVSFKEHEYLGNLSAVSSTEGTIEETLNEASKELSERATNPFVDRALTEFSELEYSEMGSSFTGSPKVESAILVENPKDEGTVRSRDKEDLVSSAALHNPLESPMTLPKVVKEDRVVSPEKTKDILNEMQVSVVAPMREEYADFKPFEQAWEVKDTYEGTRDVLAARGNLENRMDKKSFEDNLEQKSHGKDSESSNDDTSFPSTPEPVKDGSRAYITCASFTSASDSTAASIFPLLEDHASENKTDEKKIEERKAQITTDKTSPQTSNPFLVGTQDSEADYVTTDNLSKVTKEEVASMPEGLTPDLVQEACESELNEATGTKMAYETKMDLVQTSEALQESLYPTAQLCPSFEESEATPSPVLPDIVMEAPLNSLLPNAGASAAQHSVSPLGAPASASYDSSKLEPENPPPYEEAMNVAPKALGIKEEIKEPESINAAVQETEAPYISIACDLIKETKLSTEPSPDFSNYSEIAKFEKLVPDHVELVEDSSPDSEPVDLFSDDSIPEVPQTQEEAVMLMKESLAEVSEMVTQHKHEERLSASPQEVGKPYLEAFQPSLHITKDAAPNEIPALTKKEKIPLQMEELNTSIYSNDGLLTSKEDKIKESETFSDSSPIEIIDEFPAFISSKTDSSPKLAKEYTDLEISNKSEIANVQSKAGSLPCSELPHDLSFKNIHPKDEVHVSDEFSKDRSSVSKVSLLPSSISALEPRTEMGSLVKPQVLMKEAEKKLPSDTEREDRSLSALFSSELSKISVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVTVSEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGLANKSVKEAMAKIQAKIPGLKRKAE", "length": 1172, "header": "tr|A0A9J7EZJ9-1|A0A9J7J7W4_CRIGR Computationally mapped isoform of Reticulon OS=Cricetulus griseus OX=10029 GN=Rtn4 PE=4 SV=1 CANONICAL=A0A9J7J7W4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F0P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4/entry#A0A9J7F0P3-1", "sequence": { "sequence": "MEDLDQSPLVSSTADSPSRPPPPPAFKYQFVTEPEDEEDEEEEEDEEDEDEDLEELEVLERKPAAGLSAAPVPPAAAAPLLDLGSDSVPPAPRGPLLAAPPAAPERQPSWERSPAAPAQSLPAAAAVLPSKLPEDDEPPARPPPPPPAGVSPLAEPAAPPSTPAAPKRRGSGSVGECRGAPAPTPLPLVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVTVSEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGLANKSVKEAMAKIQAKIPGLKRKAE", "length": 376, "header": "tr|A0A9J7F0P3-1|A0A9J7J7W4_CRIGR Computationally mapped isoform of Reticulon OS=Cricetulus griseus OX=10029 GN=Rtn4 PE=4 SV=1 CANONICAL=A0A9J7J7W4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J7W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4/entry#A0A9J7J7W4-1", "sequence": { "sequence": "MEDLDQSPLVSSTADSPSRPPPPPAFKYQFVTEPEDEEDEEEEEDEEDEDEDLEELEVLERKPAAGLSAAPVPPAAAAPLLDLGSDSVPPAPRGPLLAAPPAAPERQPSWERSPAAPAQSLPAAAAVLPSKLPEDDEPPARPPPPPPAGVSPLAEPAAPPSTPAAPKRRGSGSVGECRGAPAPTPLPLDETLFALPAASEPVIPSSAEKSMDLKEQPGDTVPSAQEDFPSVPLETAASLPSLSPLSTVSFKEHEYLGNLSAVSSTEGTIEETLNEASKELSERATNPFVDRALTEFSELEYSEMGSSFTGSPKVESAILVENPKDEGTVRSRDKEDLVSSAALHNPLESPMTLPKVVKEDRVVSPEKTKDILNEMQVSVVAPMREEYADFKPFEQAWEVKDTYEGTRDVLAARGNLENRMDKKSFEDNLEQKSHGKDSESSNDDTSFPSTPEPVKDGSRAYITCASFTSASDSTAASIFPLLEDHASENKTDEKKIEERKAQITTDKTSPQTSNPFLVGTQDSEADYVTTDNLSKVTKEEVASMPEGLTPDLVQEACESELNEATGTKMAYETKMDLVQTSEALQESLYPTAQLCPSFEESEATPSPVLPDIVMEAPLNSLLPNAGASAAQHSVSPLGAPASASYDSSKLEPENPPPYEEAMNVAPKALGIKEEIKEPESINAAVQETEAPYISIACDLIKETKLSTEPSPDFSNYSEIAKFEKLVPDHVELVEDSSPDSEPVDLFSDDSIPEVPQTQEEAVMLMKESLAEVSEMVTQHKHEERLSASPQEVGKPYLEAFQPSLHITKDAAPNEIPALTKKEKIPLQMEELNTSIYSNDGLLTSKEDKIKESETFSDSSPIEIIDEFPAFISSKTDSSPKLAKEYTDLEISNKSEIANVQSKAGSLPCSELPHDLSFKNIHPKDEVHVSDEFSKDRSSVSKVSLLPSSISALEPRTEMGSLVKPQVLMKEAEKKLPSDTEREDRSLSALFSSELSKISVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVTVSEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGLANKSVKEAMAKIQAKIPGLKRKAE", "length": 1186, "header": "tr|A0A9J7J7W4-1|A0A9J7J7W4_CRIGR Isoform 1 of Reticulon OS=Cricetulus griseus OX=10029 GN=Rtn4 PE=4 SV=1 CANONICAL=A0A9J7J7W4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 162, "start_aa": "Thr", "end_pos": 162, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr162", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 184, "start_aa": "Thr", "end_pos": 184, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr184", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 604, "start_aa": "Thr", "end_pos": 604, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr604", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EV09", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EV09" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EV09", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EV09" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764263", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764263", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7W4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7W4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7W4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7W4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7W4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4" } ], "pmid": "" }, { "name": "endoplasmic reticulum tubular network formation", "id": "GO:0071787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071787", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7W4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1094, "end_pos": 1096, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1164, "end_pos": 1166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 532, "end_pos": 534, "annotation": "n_glycosylation_sequon" }, { "start_pos": 715, "end_pos": 717, "annotation": "n_glycosylation_sequon" }, { "start_pos": 832, "end_pos": 834, "annotation": "n_glycosylation_sequon" }, { "start_pos": 892, "end_pos": 894, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J7W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7W4" }, { "id": "PS50845", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50845" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reticulon", "eco_id": "ECO_0000259", "start_pos": 999, "end_pos": 1186, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 162, 184, 604 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1094, "end_pos": 1096 }, { "start_pos": 1164, "end_pos": 1166 }, { "start_pos": 258, "end_pos": 260 }, { "start_pos": 489, "end_pos": 491 }, { "start_pos": 532, "end_pos": 534 }, { "start_pos": 715, "end_pos": 717 }, { "start_pos": 832, "end_pos": 834 }, { "start_pos": 892, "end_pos": 894 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J874-1", "uniprot_ac": "A0A9J7J874", "uniprot_id": "A0A9J7J874_CRIGR", "mass": { "chemical_mass": 53579.0, "monoisotopic_mass": 53579.0 }, "refseq": { "ac": "XP_027244244", "name": "septin-11 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244244" }, "gene_names": [ { "name": "Septin11", "type": "recommended", "evidence": [ { "id": "A0A9J7J874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J874" } ] }, { "name": "Septin11", "type": "synonym", "evidence": [ { "id": "XP_027244244", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244244" } ] } ], "protein_names": [ { "name": "Septin", "type": "recommended", "evidence": [ { "id": "A0A9J7J874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J874/entry#names_and_taxonomy" } ] }, { "name": "septin-11 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027244244", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244244" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027244244", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244244" } ] }, { "annotation": "Filament-forming cytoskeletal GTPase.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F083", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F083#function" }, { "database": "UniProtKB", "id": "PIRNR006698", "url": "https://www.uniprot.org/uniprotkb/PIRNR006698#function" }, { "database": "UniProtKB", "id": "A0A9J7EVL5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVL5#function" }, { "database": "UniProtKB", "id": "A0A9J7EXW7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXW7#function" }, { "database": "UniProtKB", "id": "A0A9J7F058", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F058#function" }, { "database": "UniProtKB", "id": "A0A9J7F196", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F196#function" }, { "database": "UniProtKB", "id": "A0A9J7J4Q8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4Q8#function" }, { "database": "UniProtKB", "id": "A0A9J7J874", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J874#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J874", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J874" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Septin11", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J874", "locus": {} } ], "crossref": [ { "id": "A0A9J7J874", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J874", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01850", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01850", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752472", "url": "https://www.ncbi.nlm.nih.gov/gene/100752472", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752472", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752472", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7J874", "url": "https://www.orthodb.org/?gene=A0A9J7J874", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00735", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00735", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027244244", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244244", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7EVL5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EVL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EXW7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EXW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F058", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F058", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F058-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F058-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F083", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F083", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F083-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F083-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F196", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F196", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F196-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F196-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J4Q8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J4Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J874", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J874", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J874-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J874-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGSRKRKEGRNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKDLEEEVSNFQKKKAAAQLLQAQAQQSGAQQTKKDKDKKKVIFQTLQVSCSSAQMTCSISLRLLMSENLLLQMFLPQ", "length": 464, "header": "tr|A0A9J7J874-1|A0A9J7J874_CRIGR Isoform 1 of Septin OS=Cricetulus griseus OX=10029 GN=Septin11 PE=3 SV=1 CANONICAL=A0A9J7J874-1" }, "isoforms": [ { "isoform_ac": "A0A9J7EVL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J874/entry#A0A9J7EVL5-1", "sequence": { "sequence": "MRGSRKRKEGRNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKDLEEEVSNFQKKKAAAQLLQAQAQQSGAQQTKKDKDKKN", "length": 427, "header": "tr|A0A9J7EVL5-1|A0A9J7J874_CRIGR Computationally mapped isoform of Septin OS=Cricetulus griseus OX=10029 GN=Septin11 PE=3 SV=1 CANONICAL=A0A9J7J874-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EXW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J874/entry#A0A9J7EXW7-1", "sequence": { "sequence": "MRGSRKRKEGRNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKDLEEEVSNFQKKKAAAQLLQAQAQQSGAQQTKKDKDKKNASFT", "length": 431, "header": "tr|A0A9J7EXW7-1|A0A9J7J874_CRIGR Computationally mapped isoform of Septin OS=Cricetulus griseus OX=10029 GN=Septin11 PE=3 SV=1 CANONICAL=A0A9J7J874-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F058-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J874/entry#A0A9J7F058-1", "sequence": { "sequence": "MRGSRKRKEGRNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKDLEEEVSNFQKKKAAAQLLQAQAQQSGAQQTKKDKDKKKKLKFRTK", "length": 434, "header": "tr|A0A9J7F058-1|A0A9J7J874_CRIGR Computationally mapped isoform of Septin OS=Cricetulus griseus OX=10029 GN=Septin11 PE=3 SV=1 CANONICAL=A0A9J7J874-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F083-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J874/entry#A0A9J7F083-1", "sequence": { "sequence": "MAVAVGRQSNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKDLEEEVSNFQKKKAAAQLLQAQAQQSGAQQTKKDKDKKKVIFQTLQVSCSSAQMTCSISLRLLMSENLLLQMFLPQ", "length": 462, "header": "tr|A0A9J7F083-1|A0A9J7J874_CRIGR Computationally mapped isoform of Septin OS=Cricetulus griseus OX=10029 GN=Septin11 PE=3 SV=1 CANONICAL=A0A9J7J874-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F196-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J874/entry#A0A9J7F196-1", "sequence": { "sequence": "MRGSRKRKEGRNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKDLEEEVSNFQKKKAAAQLLQAQAQQSGAQQTKKDKDKKNFFFM", "length": 431, "header": "tr|A0A9J7F196-1|A0A9J7J874_CRIGR Computationally mapped isoform of Septin OS=Cricetulus griseus OX=10029 GN=Septin11 PE=3 SV=1 CANONICAL=A0A9J7J874-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J4Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J874/entry#A0A9J7J4Q8-1", "sequence": { "sequence": "MRGSRKRKEGRNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKDLEEEVSNFQKKKAAAQLLQAQAQQSGAQQTKKDKDKKK", "length": 427, "header": "tr|A0A9J7J4Q8-1|A0A9J7J4Q8_CRIGR Computationally mapped isoform of Septin OS=Cricetulus griseus OX=10029 GN=Septin11 PE=3 SV=1 CANONICAL=A0A9J7J874-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J874-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J874/entry#A0A9J7J874-1", "sequence": { "sequence": 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Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 550 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614671.1) and transcript sequences (IACG01092087.1 and IACG01092239.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007648014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648014" } ] }, { "annotation": "Component of an histone acetyltransferase complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6B7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B7#function" }, { "database": "UniProtKB", "id": "RU361213", "url": "https://www.uniprot.org/uniprotkb/RU361213#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6B7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ing1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6B7", 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027243772", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243772" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J246", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ppp4r3b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246", "locus": {} } ], "crossref": [ { "id": "A0A9J7J246", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J246", "database": "AlphaFoldDB", "categories": [] }, { "id": "100767958", "url": "https://www.ncbi.nlm.nih.gov/gene/100767958", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006887", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006887", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767958", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767958", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7J246", "url": "https://www.orthodb.org/?gene=A0A9J7J246", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23318", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23318", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23318:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23318:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04802", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04802", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22972", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22972", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027243772", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243772", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LDB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LDB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EVZ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EVZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J246", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J246-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J6E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J6E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6E5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPTCELSKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACEDLENNEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQQLFLFMQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKDNMLGSNKTNTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEDDEEMWFNEDDDEEGKAVVIPIEKSKTEDDFPDSYEKFMETKKAKESEDKENLPKRTSSGGFKFTFSHSPSAANGTNSANSKSVVAQTTSASSNGSSSKTTNLAASVTATKGSLVGLVDYPDDEEEDEEEESSPRKRPRLGS", "length": 827, "header": "tr|A0A9J7J246-1|A0A9J7J246_CRIGR Isoform 1 of Serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X3 OS=Cricetulus griseus OX=10029 GN=Ppp4r3b PE=3 SV=1 CANONICAL=A0A9J7J246-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LDB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246/entry#A0A8C2LDB2-1", "sequence": { "sequence": "MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPTCELSKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACEDLENNEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKDNMLGSNKTNTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEDDEEMWFNEDDDEEGKAVVIPIEKSKTEDDFPDSYEKFMETKKAKESEDKENLPKRTSSGGFKFTFSHSPSAANGTNSANSKSVVAQTTSASSNGSSSKTTNLAASVTATKGSLVGLVDYPDDEEEDEEEESSPRKRPRLGS", "length": 820, "header": "tr|A0A8C2LDB2-1|A0A8C2LDB2_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X4 OS=Cricetulus griseus OX=10029 GN=Ppp4r3b PE=3 SV=1 CANONICAL=A0A9J7J246-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EVZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246/entry#A0A9J7EVZ1-1", "sequence": { "sequence": "MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPTCELSKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACEDLENNEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEDDEEMWFNEDDDEEGKAVVIPIEKSKTEDDFPDSYEKFMETKKAKESEDKENLPKRTSSGGFKFTFSHSPSAANGTNSANSKSVVAQTTSASSNGSSSKTTNLAASVTATKGSLVGLVDYPDDEEEDEEEESSPRKRPRLGS", "length": 806, "header": "tr|A0A9J7EVZ1-1|A0A9J7J246_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X3 OS=Cricetulus griseus OX=10029 GN=Ppp4r3b PE=3 SV=1 CANONICAL=A0A9J7J246-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J246-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246/entry#A0A9J7J246-1", "sequence": { "sequence": "MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPTCELSKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACEDLENNEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQQLFLFMQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKDNMLGSNKTNTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEDDEEMWFNEDDDEEGKAVVIPIEKSKTEDDFPDSYEKFMETKKAKESEDKENLPKRTSSGGFKFTFSHSPSAANGTNSANSKSVVAQTTSASSNGSSSKTTNLAASVTATKGSLVGLVDYPDDEEEDEEEESSPRKRPRLGS", "length": 827, "header": "tr|A0A9J7J246-1|A0A9J7J246_CRIGR Isoform 1 of Serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X3 OS=Cricetulus griseus OX=10029 GN=Ppp4r3b PE=3 SV=1 CANONICAL=A0A9J7J246-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J6E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246/entry#A0A9J7J6E5-1", "sequence": { "sequence": "MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPTCELSKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACEDLENNEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQQLFLFMQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEDDEEMWFNEDDDEEGKAVVIPIEKSKTEDDFPDSYEKFMETKKAKESEDKENLPKRTSSGGFKFTFSHSPSAANGTNSANSKSVVAQTTSASSNGSSSKTTNLAASVTATKGSLVGLVDYPDDEEEDEEEESSPRKRPRLGS", "length": 813, "header": "tr|A0A9J7J6E5-1|A0A9J7J6E5_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X5 OS=Cricetulus griseus OX=10029 GN=Ppp4r3b PE=3 SV=1 CANONICAL=A0A9J7J246-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 279, "start_aa": "Thr", "end_pos": 279, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr279", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EVZ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVZ1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EVZ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVZ1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767958", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767958", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J246", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246" } ], "pmid": "" }, { "name": "protein phosphatase 4 complex", "id": "GO:0030289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030289", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J246", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J246", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J246", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J246", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J246", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J246", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246" } ], "pmid": "" }, { "name": "positive regulation of gluconeogenesis", "id": "GO:0045722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045722", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J246", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246" } ], "pmid": "" }, { "name": "regulation of double-strand break repair", "id": "GO:2000779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000779", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J246", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein phosphatase activator activity", "id": "GO:0072542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072542", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J246", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 503, "end_pos": 505, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 759, "end_pos": 761, "annotation": "n_glycosylation_sequon" }, { "start_pos": 779, "end_pos": 781, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J246", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246" }, { "id": "PF22972", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22972" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PP4R3 EVH1-like", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 103, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7J246", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J246" }, { "id": "PF04802", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04802" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serine/threonine-protein phosphatase 4 regulatory subunit 3-like central", "eco_id": "ECO_0000259", "start_pos": 144, "end_pos": 656, "start_aa": "Glu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 279 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 462, "end_pos": 464 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 503, "end_pos": 505 }, { "start_pos": 600, "end_pos": 602 }, { "start_pos": 759, "end_pos": 761 }, { "start_pos": 779, "end_pos": 781 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J374-1", "uniprot_ac": "A0A9J7J374", "uniprot_id": "A0A9J7J374_CRIGR", "mass": { "chemical_mass": 149637.0, "monoisotopic_mass": 149637.0 }, "refseq": { "ac": "XP_027245781", "name": "calcium-dependent secretion activator 2 isoform X17", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245781" }, "gene_names": [ { "name": "Cadps2", "type": "recommended", "evidence": [ { "id": "A0A9J7J374", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374" } ] }, { "name": "Cadps2", "type": "synonym", "evidence": [ { "id": "XP_027245781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245781" } ] } ], "protein_names": [ { "name": "Calcium-dependent secretion activator 2 isoform X17", "type": "synonym", "evidence": [ { "id": "A0A9J7J374", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#names_and_taxonomy" } ] }, { "name": "calcium-dependent secretion activator 2 isoform X17", "type": "synonym", "evidence": [ { "id": "XP_027245781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245781" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027245781", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245781" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J374", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cadps2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374", "locus": {} } ], "crossref": [ { "id": "cd01234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752027", "url": "https://www.ncbi.nlm.nih.gov/gene/100752027", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752027", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752027", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7J374", "url": "https://www.orthodb.org/?gene=A0A9J7J374", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12166:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12166:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06292", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06292", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25341", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25341", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027245781", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245781", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7EXI5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EXI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EXJ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EXJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EYK5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EYK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EZV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EZV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F1Z7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F1Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F217", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F217", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F217-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F217-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F248", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F248", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F248-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F248-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2P1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2P1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2P1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2V8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2V8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F366", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F366", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F366-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F366-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCD0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J374", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J374-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J5P6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J5P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5P6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7K2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7K2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7P4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J966", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J966", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J966-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J966-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLFGKDADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEGPAEKETETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVKNIANSLPNVALPKVPSLPLNLPQIPSFSTPPWMASLYESTNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEFRSQWQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1312, "header": "tr|A0A9J7J374-1|A0A9J7J374_CRIGR Isoform 1 of Calcium-dependent secretion activator 2 isoform X17 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "isoforms": [ { "isoform_ac": "A0A9J7EXI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7EXI5-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLYADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVNNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEFRSQWQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1259, "header": "tr|A0A9J7EXI5-1|A0A9J7J374_CRIGR Computationally mapped isoform of Calcium-dependent secretion activator 2 isoform X17 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EXJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7EXJ1-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLYADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVKNIANSLPNVALPKVPSLPLNLPQIPSFSTPPWMASLYESTNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1297, "header": "tr|A0A9J7EXJ1-1|A0A9J7J374_CRIGR Computationally mapped isoform of Calcium-dependent secretion activator 2 isoform X17 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EYK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7EYK5-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLFGKDADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEGPAEKETETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVKNIANSLPNVALPKVPSLPLNLPQIPSFSTPPWMASLYESTNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1304, "header": "tr|A0A9J7EYK5-1|A0A9J7J374_CRIGR Computationally mapped isoform of Calcium-dependent secretion activator 2 isoform X17 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EZV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7EZV9-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLYADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEGPAEKETETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVNNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1261, "header": "tr|A0A9J7EZV9-1|A0A9J7J374_CRIGR Computationally mapped isoform of Calcium-dependent secretion activator 2 isoform X17 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F1Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7F1Z7-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLYADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVNNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1254, "header": "tr|A0A9J7F1Z7-1|A0A9J7J374_CRIGR Computationally mapped isoform of Calcium-dependent secretion activator 2 isoform X17 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F217-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7F217-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLFGKDADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEGPAEKETETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVNNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1264, "header": "tr|A0A9J7F217-1|A0A9J7J374_CRIGR Computationally mapped isoform of Calcium-dependent secretion activator 2 isoform X17 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F248-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7F248-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLYADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEGPAEKETETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVNNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1264, "header": "tr|A0A9J7F248-1|A0A9J7J374_CRIGR Computationally mapped isoform of Calcium-dependent secretion activator 2 isoform X17 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F2P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7F2P1-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLFGKDADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEGPAEKETETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVNNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEFRSQWQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1272, "header": "tr|A0A9J7F2P1-1|A0A9J7J374_CRIGR Computationally mapped isoform of Calcium-dependent secretion activator 2 isoform X17 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F2V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7F2V8-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLFGKDADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVKNIANSLPNVALPKVPSLPLNLPQIPSFSTPPWMASLYESTNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1300, "header": "tr|A0A9J7F2V8-1|A0A9J7J374_CRIGR Computationally mapped isoform of Calcium-dependent secretion activator 2 isoform X17 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F366-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7F366-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLFGKDADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVNNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1260, "header": "tr|A0A9J7F366-1|A0A9J7J374_CRIGR Computationally mapped isoform of Calcium-dependent secretion activator 2 isoform X17 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HCD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7HCD0-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLCKFYADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEGQKQVMFLHAHATLSNVVMDRNILNQEDLEFEANLGRLATPARKLEEVLHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVNNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1290, "header": "tr|A0A9J7HCD0-1|A0A9J7HCD0_CRIGR Computationally mapped isoform of Calcium-dependent secretion activator 2 isoform X23 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J374-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7J374-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLFGKDADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEGPAEKETETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVKNIANSLPNVALPKVPSLPLNLPQIPSFSTPPWMASLYESTNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEFRSQWQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1312, "header": "tr|A0A9J7J374-1|A0A9J7J374_CRIGR Isoform 1 of Calcium-dependent secretion activator 2 isoform X17 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J5P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7J5P6-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLFGKDADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVNNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1257, "header": "tr|A0A9J7J5P6-1|A0A9J7J5P6_CRIGR Computationally mapped isoform of Calcium-dependent secretion activator 2 isoform X31 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J7K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7J7K2-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLFGKDADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEGPAEKETETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVKNIANSLPNVALPKVPSLPLNLPQIPSFSTPPWMASLYESTNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1307, "header": "tr|A0A9J7J7K2-1|A0A9J7J7K2_CRIGR Computationally mapped isoform of Calcium-dependent secretion activator 2 isoform X18 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J7P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7J7P4-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLYADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEGPAEKETETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVKNIANSLPNVALPKVPSLPLNLPQIPSFSTPPWMASLYESTNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1304, "header": "tr|A0A9J7J7P4-1|A0A9J7J7P4_CRIGR Computationally mapped isoform of Calcium-dependent secretion activator 2 isoform X19 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J966-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7J966-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGHVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPVVQSQKLNPKGGTLHADAQLFGKDADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEGPAEKETETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVNNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1267, "header": "tr|A0A9J7J966-1|A0A9J7J966_CRIGR Computationally mapped isoform of Calcium-dependent secretion activator 2 isoform X25 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KEM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374/entry#A0A9J7KEM2-1", "sequence": { "sequence": "MLDPSSSEEESDEGLEEESREVLVAPGGSQRAPPAAAREGRRDAPGRSGGGGGGGAARPVSPSPSVLSEGREDPERQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFVSKEMETMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMIVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPDADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSIEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEGPAEKETETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVNNGSTTSEDLFWKLDALQMFVYDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEFRSQWQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILRDKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG", "length": 1202, "header": "tr|A0A9J7KEM2-1|A0A9J7J374_CRIGR Computationally mapped isoform of Calcium-dependent secretion activator 2 isoform X17 OS=Cricetulus griseus OX=10029 GN=Cadps2 PE=4 SV=1 CANONICAL=A0A9J7J374-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EXI5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXI5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EXI5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXI5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752027", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752027", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J374", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J374", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J374", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J374", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374" } ], "pmid": "" }, { "name": "synaptic vesicle exocytosis", "id": "GO:0016079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016079", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J374", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374" } ], "pmid": "" }, { "name": "positive regulation of exocytosis", "id": "GO:0045921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045921", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J374", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374" } ], "pmid": "" }, { "name": "dense core granule exocytosis", "id": "GO:1990504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990504", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J374", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J374", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J374", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J374" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1015, 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RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027244993", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244993" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J772", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J772" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf318", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J772", "locus": {} } ], "crossref": [ { "id": "100757338", "url": "https://www.ncbi.nlm.nih.gov/gene/100757338", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] 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"MYRSGSRSSVSSHRAKDGGVSGPRPGRPGGASSGPARRPSSPPPSTSSSLRLPARRHRSPSGHRGRRASPSPPRGRRGSPSPPRGRRASPSPPRGRRASPSPPRGRRVSPSPPRARRGSPSPPRSRRLYPPGLAGFRGSTRGESRADFARDGRGDHPGDGGSRRHSPGLCSDSSLEQSLRITVGNDHFCVNTPERRRLSDRLGSPVDNLEDMDRDDLTDDSVFTRTSKCSRGLERYISREEGPLSPFLGQLDEEYRARETFLHRTEYSPHVSCHDELLRGAERNREKLKSSSYSIRAEERSRETKRPRYDDTEKVHSIGGDHSSFTSGTRNYRQRRRSPSPRFLDPEFRELDLARRKREEEEEQNRSLGQELVGADDDQTSCSIPGLSNVLTTSEPGYSLHRPEEVSVLPKKSILKKRIEVDMKPSLQLESFSGSTSSSQDHSLYSEHSPLPLSGAIAAFASEIENKGTTVEADLKEPQSNLYQWGLLHETPKDNNPLAEKFDSFLCYKEKLNLKAEGLERHADFLLPHERASQDGSGFSRILSMLADSTSTQEKRRRSFPDIEDEEKFLYGDEEEDIKAESPPKSLGDSENKGSRQKASSVPSTPAIKLESLEESNPEYSKIHDLLKTIGLDIGVAEISKLAARTQERLHGKKPSSRSLADRRPSADRHFSADRGSSVEHSFITDRRSSDSHRLESRESHHSNTQSPEVSHPLPASPVDPYLLTKSSPPFLKADHPLGHVPGPEVVGSGFQSPVAVRCMMPSAPPTPIRLPHSAPLPQFYIPRASQFATPRIPPNYQGSVIPSAPFDAYRHYMAYTASRWPMYPASQPSSHTLQEPHRLIPTTKQTTHSSRPNLRVIPTVTPEKSKQEVSVLGSISVKQVPIQVSPSLIRYNPEKISDEKNRASQKQKVIEEREKLKTDQEARQKKMFYLRTELERLHKQQGHSGEMLRKKRREKDGHKDPLLMEVSRLQDSIMKDIAELHKETEEAEKKQSELDKVAQILGIDIFDKSLKSSNDSKESTEKPEKGEKSKSPERELLTSNSSSNNQESKVNEKSCIKNPNSAESLQPTSKQSDQPVAVYEYYDAGNHWCKDCNTICGTMFDFFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDTVKRTDKITVPAKGSEFLVPITGFYCQLCEEFLGDPISGEQHVKGHQHNEKYKKYVEENPLYEERRNLDRQAGLAVVLETERRRQNELKRKLSEKPKEEKIEKKAKVVKEAKEDDKTSIELEDQLSEGGNSPEKGEVKRNASLKLPVREEIKKESSIASSFGKFSWKKPEKEEEKGSMVPLSAPKEDTIENSKDKDDGKAETGKTKPIKIKLSGKTVVAHTSPWTPVVTTSTQTKIRPNLPIPSMVLRKSGSATVSKPAPLNTFLSIKSSGTSARPLPVVKESSSDLLLPPDIISKAFGGEEVILKGSPEEKVELAEKNEPSQVPEQLLALPPPPPPPPPPPPPPPLVIPHLSAPSPAQANVLAPVKSNSVVSQTLGLGFQGPEILNSGLPVAFTASEQPAAIPSDETAPGVSESDRDQTLISMLVRPPPPLSSVFSEQAKKLEKRNLCLATANAKDLYDIFYSSGGKGAHETKLSGSPLANGENSSLFRTENSDISSTSTLNSSVSSEDLPQDSGLVTAPVNSKLEDPIPKGLVSIGKWSVVDHIDPKSRDSSYSFLQPLTRLYQNRPYEMVVPKTDTSAVWTSASFQSDTNKDRPPEGKIKSDLGEPGPPGTDSASHLSDTHCHTKGSQKLVEINFIDKQNKNQELGQSEDCREREMKRNTELKEKVAVEEEAGTNIGLHSIEDSNLNHGSRNTWEGEIGQPKLSTIDKEVEQSRKLMTGHENPSKVVIESNQSLASKRAKIDSFPSLLQNPKDVPELLLLSPPRSDMCLKKPETWESPKKPEGSPEKPGVEAVELQDTHPELTVAKESKALENFEATHLKAEGLVTLRNLGDVHADFRNVQIEQAHRSPTALSQKMCEENSVLSVVCNLSSPSDFEPIQSFSGFLLESPKTLVLNFGTEGEHSSSNSRNGRIASNCLETGHPVENVDHDLGGERTHQALDLLAGGMLSEEVKGTSQLPEDLLRVESTTVGPSGLGPSPCLPDLVDFVTRTSGAPKEKPCSPLCEPGDFLTCNSLGMGSPPLEIVNVSVSEVVSQASEDNDSALNLVKSPTSGSPSRDQVVGGNMDPQEITEQEAAVDVIPDHTRSSVHDYSSQDYLNG", "length": 2235, "header": "tr|A0A9J7J772-1|A0A9J7J772_CRIGR Isoform 1 of Zinc finger protein 318 isoform X2 OS=Cricetulus griseus OX=10029 GN=Znf318 PE=4 SV=1 CANONICAL=A0A9J7J772-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LAJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J772/entry#A0A8C2LAJ5-1", "sequence": { "sequence": 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"length": 1151, "header": "tr|A0A8C2LAJ5-1|A0A8C2LAJ5_CRIGR Computationally mapped isoform of Zinc finger protein 318 isoform X4 OS=Cricetulus griseus OX=10029 GN=Znf318 PE=4 SV=1 CANONICAL=A0A9J7J772-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EXK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J772/entry#A0A9J7EXK3-1", "sequence": { "sequence": 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"length": 2232, "header": "tr|A0A9J7EXK3-1|A0A9J7J772_CRIGR Computationally mapped isoform of Zinc finger protein 318 isoform X2 OS=Cricetulus griseus OX=10029 GN=Znf318 PE=4 SV=1 CANONICAL=A0A9J7J772-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J772-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J772/entry#A0A9J7J772-1", "sequence": { "sequence": "MYRSGSRSSVSSHRAKDGGVSGPRPGRPGGASSGPARRPSSPPPSTSSSLRLPARRHRSPSGHRGRRASPSPPRGRRGSPSPPRGRRASPSPPRGRRASPSPPRGRRVSPSPPRARRGSPSPPRSRRLYPPGLAGFRGSTRGESRADFARDGRGDHPGDGGSRRHSPGLCSDSSLEQSLRITVGNDHFCVNTPERRRLSDRLGSPVDNLEDMDRDDLTDDSVFTRTSKCSRGLERYISREEGPLSPFLGQLDEEYRARETFLHRTEYSPHVSCHDELLRGAERNREKLKSSSYSIRAEERSRETKRPRYDDTEKVHSIGGDHSSFTSGTRNYRQRRRSPSPRFLDPEFRELDLARRKREEEEEQNRSLGQELVGADDDQTSCSIPGLSNVLTTSEPGYSLHRPEEVSVLPKKSILKKRIEVDMKPSLQLESFSGSTSSSQDHSLYSEHSPLPLSGAIAAFASEIENKGTTVEADLKEPQSNLYQWGLLHETPKDNNPLAEKFDSFLCYKEKLNLKAEGLERHADFLLPHERASQDGSGFSRILSMLADSTSTQEKRRRSFPDIEDEEKFLYGDEEEDIKAESPPKSLGDSENKGSRQKASSVPSTPAIKLESLEESNPEYSKIHDLLKTIGLDIGVAEISKLAARTQERLHGKKPSSRSLADRRPSADRHFSADRGSSVEHSFITDRRSSDSHRLESRESHHSNTQSPEVSHPLPASPVDPYLLTKSSPPFLKADHPLGHVPGPEVVGSGFQSPVAVRCMMPSAPPTPIRLPHSAPLPQFYIPRASQFATPRIPPNYQGSVIPSAPFDAYRHYMAYTASRWPMYPASQPSSHTLQEPHRLIPTTKQTTHSSRPNLRVIPTVTPEKSKQEVSVLGSISVKQVPIQVSPSLIRYNPEKISDEKNRASQKQKVIEEREKLKTDQEARQKKMFYLRTELERLHKQQGHSGEMLRKKRREKDGHKDPLLMEVSRLQDSIMKDIAELHKETEEAEKKQSELDKVAQILGIDIFDKSLKSSNDSKESTEKPEKGEKSKSPERELLTSNSSSNNQESKVNEKSCIKNPNSAESLQPTSKQSDQPVAVYEYYDAGNHWCKDCNTICGTMFDFFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDTVKRTDKITVPAKGSEFLVPITGFYCQLCEEFLGDPISGEQHVKGHQHNEKYKKYVEENPLYEERRNLDRQAGLAVVLETERRRQNELKRKLSEKPKEEKIEKKAKVVKEAKEDDKTSIELEDQLSEGGNSPEKGEVKRNASLKLPVREEIKKESSIASSFGKFSWKKPEKEEEKGSMVPLSAPKEDTIENSKDKDDGKAETGKTKPIKIKLSGKTVVAHTSPWTPVVTTSTQTKIRPNLPIPSMVLRKSGSATVSKPAPLNTFLSIKSSGTSARPLPVVKESSSDLLLPPDIISKAFGGEEVILKGSPEEKVELAEKNEPSQVPEQLLALPPPPPPPPPPPPPPPLVIPHLSAPSPAQANVLAPVKSNSVVSQTLGLGFQGPEILNSGLPVAFTASEQPAAIPSDETAPGVSESDRDQTLISMLVRPPPPLSSVFSEQAKKLEKRNLCLATANAKDLYDIFYSSGGKGAHETKLSGSPLANGENSSLFRTENSDISSTSTLNSSVSSEDLPQDSGLVTAPVNSKLEDPIPKGLVSIGKWSVVDHIDPKSRDSSYSFLQPLTRLYQNRPYEMVVPKTDTSAVWTSASFQSDTNKDRPPEGKIKSDLGEPGPPGTDSASHLSDTHCHTKGSQKLVEINFIDKQNKNQELGQSEDCREREMKRNTELKEKVAVEEEAGTNIGLHSIEDSNLNHGSRNTWEGEIGQPKLSTIDKEVEQSRKLMTGHENPSKVVIESNQSLASKRAKIDSFPSLLQNPKDVPELLLLSPPRSDMCLKKPETWESPKKPEGSPEKPGVEAVELQDTHPELTVAKESKALENFEATHLKAEGLVTLRNLGDVHADFRNVQIEQAHRSPTALSQKMCEENSVLSVVCNLSSPSDFEPIQSFSGFLLESPKTLVLNFGTEGEHSSSNSRNGRIASNCLETGHPVENVDHDLGGERTHQALDLLAGGMLSEEVKGTSQLPEDLLRVESTTVGPSGLGPSPCLPDLVDFVTRTSGAPKEKPCSPLCEPGDFLTCNSLGMGSPPLEIVNVSVSEVVSQASEDNDSALNLVKSPTSGSPSRDQVVGGNMDPQEITEQEAAVDVIPDHTRSSVHDYSSQDYLNG", "length": 2235, "header": "tr|A0A9J7J772-1|A0A9J7J772_CRIGR Isoform 1 of Zinc finger protein 318 isoform X2 OS=Cricetulus griseus OX=10029 GN=Znf318 PE=4 SV=1 CANONICAL=A0A9J7J772-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 605, "start_aa": "Thr", "end_pos": 605, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr605", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EXK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXK3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EXK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXK3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757338", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757338", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J772", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J772" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J772", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J772" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J772", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J772" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J772", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J772" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J772", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J772" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1015, "end_pos": 1017, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1041, "end_pos": 1043, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1274, "end_pos": 1276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1619, "end_pos": 1621, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1637, "end_pos": 1639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1868, "end_pos": 1870, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2005, "end_pos": 2007, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2162, "end_pos": 2164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2176, "end_pos": 2178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J772" }, { "id": "SM00451", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00451" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U1-type", "eco_id": "ECO_0000259", "start_pos": 1085, "end_pos": 1119, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 605 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1015, "end_pos": 1017 }, { "start_pos": 1041, "end_pos": 1043 }, { "start_pos": 1274, "end_pos": 1276 }, { "start_pos": 1619, "end_pos": 1621 }, { "start_pos": 1637, "end_pos": 1639 }, { "start_pos": 1868, "end_pos": 1870 }, { "start_pos": 2005, "end_pos": 2007 }, { "start_pos": 2162, "end_pos": 2164 }, { "start_pos": 2176, "end_pos": 2178 }, { "start_pos": 365, "end_pos": 367 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ 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"count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J4T7-1", "uniprot_ac": "A0A9J7J4T7", "uniprot_id": "A0A9J7J4T7_CRIGR", "mass": { "chemical_mass": 107194.0, "monoisotopic_mass": 107194.0 }, "refseq": { "ac": "XP_027244369", "name": "coiled-coil alpha-helical rod protein 1 isoform X8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244369" }, "gene_names": [ { "name": "Cchcr1", "type": "recommended", "evidence": [ { "id": "A0A9J7J4T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7" } ] }, { "name": "Cchcr1", "type": "synonym", "evidence": [ { "id": "XP_027244369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244369" } ] } ], "protein_names": [ { "name": "Coiled-coil alpha-helical rod protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7J4T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7/entry#names_and_taxonomy" } ] }, { "name": "Alpha-helical coiled-coil rod protein", "type": "synonym", "evidence": [ { "id": "A0A9J7J4T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil alpha-helical rod protein 1 isoform X8", "type": "synonym", "evidence": [ { "id": "XP_027244369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244369" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027244369.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027244369", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244369" } ] }, { "annotation": "May be a regulator of keratinocyte proliferation or differentiation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EY17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY17#function" }, { "database": "UniProtKB", "id": "ARBA00003936", "url": "https://www.uniprot.org/uniprotkb/ARBA00003936#function" }, { "database": "UniProtKB", "id": "A0A9J7F1E4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E4#function" }, { "database": "UniProtKB", "id": "A0A9J7J4T7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7#function" }, { "database": "UniProtKB", "id": "A0A9J7J2E0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J2E0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J4T7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cchcr1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7", "locus": {} } ], "crossref": [ { "id": "A0A9J7J4T7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J4T7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100754418", "url": "https://www.ncbi.nlm.nih.gov/gene/100754418", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754418", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754418", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7J4T7", "url": "https://www.orthodb.org/?gene=A0A9J7J4T7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46822", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46822", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46822:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46822:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07111", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07111", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027244369", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244369", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7EY17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EY17-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F1E4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F1E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J2E0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J2E0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J2E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J2E0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J4T7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J4T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRREGPSISRPPPFLIGLQVSRVPGMGRGRQGAEKAWRSQCACVRRSSSFLLPAGGASWGFRASRQPHPPRACVLRAGSLAGKPGAKGRGKKADLALGNDPEIMARWCLDGFPNVPTIPWRELWRRGSQQARSPPDQSYRDRRHLRRKGNLHSCGQDREASDRVEMLSPSGFAGLVPPSHFQARPRMAPTWASDIPQFQSTFDQDVLERRQLDSQRPTVTMREQDVYGDGQGPGQRGRSLELRVSGALSQQAELISRQLQELRRLEEEVRMLRETSLQQKMRLEAQAMEMDALAVAEKAGQAEAEGLRAALAGAEMVRKNLEEGNQRELQEIQTLHQEQLSSMTQAHEMALASLTSKAEGLERALNSLEMKRAGEIKQLSVAQKETELLRGQLSKTQEELEAQVTLVESLRKYVGEQVPPEVHRQAWEPEREELLDTVQHLREDRADLQATVELLQVRVQSLTHMLALQEEELTRKIQPSDVLEPEYPKKCRSLLSSWREKVFVLMVQLKAQDLEHRDSMKGLRDQVAELQEQVMAQSQEQAILQQALQDKAAELEVERMSIKTLQMELNRAQEARRRQKQRTDSVEEQLKFVVSAMKSTQDSIHGTMTRLNQTVARIPSLSNRLSYAIRKVHTIKGLMARKVSLAQLRLQSCPPPPPAPPVDADLSLELEHLREERNRLDAELQLSAHIIQQEVGRAREQGEAERLQLNEVAQQLEQELQRAQESLVNVGQQLESARQGQQESTEEAANLRQELTQQQQIYGQALQEKVAEVETRLREQLSDTKRRLNEARREQAKAVVSLRQIQHRATREKERNQELRRLQDEARKEEAQRVARRVQELERDKNLMLATLRQEGLLSRYKQQRLLAMLPLGTDKKTVRFSPQPEVSPEHGCPAASPPRECTKESLTALFENLQGLSEAISREEATCPEDKQYTQCPPSDCC", "length": 943, "header": "tr|A0A9J7J4T7-1|A0A9J7J4T7_CRIGR Isoform 1 of Coiled-coil alpha-helical rod protein 1 OS=Cricetulus griseus OX=10029 GN=Cchcr1 PE=4 SV=1 CANONICAL=A0A9J7J4T7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7EY17-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7/entry#A0A9J7EY17-1", "sequence": { "sequence": "MRREGPSISRPPPFLIGLQVSRVPGMGRGRQGAEKAWRSQCACVRRSSSFLLPAGGASWGFRASRQPHPPRACVLRAGSLAGKPGAKGRGKKADLALGNDPEIMARWCLDGFPNVPTIPWRELWRRGSQQARSPPDQSYRDRRHLRRKGNLHSCGQDREASDRVEMLSPSGFAGLVPPSHFQARPRMAPTWASDIPQFQSTFDQDVLERRQLDSQRPTVTMREQDVYGDGQGPGQRGRSLELRVSGALSQQAELISRQLQELRRLEEEVRMLRETSLQQKMRLEAQAMEMDALAVAEKAGQAEAEGLRAALAGAEMVRKNLEEGNQRELQEIQTLHQEQLSSMTQAHEMALASLTSKAEGLERALNSLEMKRAGEIKQLSVAQKETELLRGQLSKTQEELEAQVTLVESLRKYVGEQVPPEVHRQAWEPEREELLDTVQHLREDRADLQATVELLQVRVQSLTHMLALQEEELTRKIQPSDVLEPEYPKKCRSLLSSWREKVFVLMVQLKAQDLEHRDSMKGLRDQVAELQEQVMAQSQEQAILQQALQDKAAELEVERMSIKTLQMELNRAQEARRRQKQRTDSVEEQLKFVVSAMKSTQDSIHGTMTRLNQTVARIPSLSNRLSYAIRKVHTIKGLMARKVSLAQLRLQSCPPPPPAPPVDADLSLELEHLREERNRLDAELQLSAHIIQQEVGRAREQGEAERLQLNEVAQQLEQELQRAQESLVNVGQQLESARQGQQESTEEAANLRQELTQQQQIYGQALQEKVAEVETRLREQLSDTKRRLNEARREQAKAVVSLRQIQHRATREKERNQELRRLQDEARKEEAQRVARRVQELERDKNLMLQRLLAMLPLGTDKKTVRFSPQPEVSPEHGCPAASPPRECTKESLTALFENLQGLSEAISREEATCPEDKQYTQCPPSDCC", "length": 929, "header": "tr|A0A9J7EY17-1|A0A9J7J4T7_CRIGR Computationally mapped isoform of Coiled-coil alpha-helical rod protein 1 OS=Cricetulus griseus OX=10029 GN=Cchcr1 PE=4 SV=1 CANONICAL=A0A9J7J4T7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F1E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7/entry#A0A9J7F1E4-1", "sequence": { "sequence": "MARWCLDGFPNVPTIPWRELWRRGSQQARSPPDQSYRDRRHLRRKGNLHSCGQDREASDRVEMLSPSGFAGLVPPSHFQARPRMAPTWASDIPQFQSTFDQDVLERRQLDSQRPTVTMREQDVYGDGQGPGQRGRSLELRVSGALSQQAELISRQLQELRRLEEEVRMLRETSLQQKMRLEAQAMEMDALAVAEKAGQAEAEGLRAALAGAEMVRKNLEEGNQRELQEIQTLHQEQLSSMTQAHEMALASLTSKAEGLERALNSLEMKRAGEIKQLSVAQKETELLRGQLSKTQEELEAQVTLVESLRKYVGEQVPPEVHRQAWEPEREELLDTVQHLREDRADLQATVELLQVRVQSLTHMLALQEEELTRKIQPSDVLEPEYPKKCRSLLSSWREKVFVLMVQLKAQDLEHRDSMKGLRDQVAELQEQVMAQSQEQAILQQALQDKAAELEVERMSIKTLQMELNRAQEARRRQKQRTDSVEEQLKFVVSAMKSTQDSIHGTMTRLNQTVARIPSLSNRLSYAIRKVHTIKGLMARKVSLAQLRLQSCPPPPPAPPVDADLSLELEHLREERNRLDAELQLSAHIIQQEVGRAREQGEAERLQLNEVAQQLEQELQRAQESLVNVGQQLESARQGQQESTEEAANLRQELTQQQQIYGQALQEKVAEVETRLREQLSDTKRRLNEARREQAKAVVSLRQIQHRATREKERNQELRRLQDEARKEEAQRVARRVQELERDKNLMLATLRQEGLLSRYKQQRLLAMLPLGTDKKTVRFSPQPEVSPEHGCPAASPPRECTKESLTALFENLQGLSEAISREEATCPEDKQYTQCPPSDCC", "length": 840, "header": "tr|A0A9J7F1E4-1|A0A9J7J4T7_CRIGR Computationally mapped isoform of Coiled-coil alpha-helical rod protein 1 OS=Cricetulus griseus OX=10029 GN=Cchcr1 PE=4 SV=1 CANONICAL=A0A9J7J4T7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J2E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7/entry#A0A9J7J2E0-1", "sequence": { "sequence": "MLSPSGFAGLVPPSHFQARPRMAPTWASDIPQFQSTFDQDVLERRQLDSQRPTVTMREQDVYGDGQGPGQRGRSLELRVSGALSQQAELISRQLQELRRLEEEVRMLRETSLQQKMRLEAQAMEMDALAVAEKAGQAEAEGLRAALAGAEMVRKNLEEGNQRELQEIQTLHQEQLSSMTQAHEMALASLTSKAEGLERALNSLEMKRAGEIKQLSVAQKETELLRGQLSKTQEELEAQVTLVESLRKYVGEQVPPEVHRQAWEPEREELLDTVQHLREDRADLQATVELLQVRVQSLTHMLALQEEELTRKIQPSDVLEPEYPKKCRSLLSSWREKVFVLMVQLKAQDLEHRDSMKGLRDQVAELQEQVMAQSQEQAILQQALQDKAAELEVERMSIKTLQMELNRAQEARRRQKQRTDSVEEQLKFVVSAMKSTQDSIHGTMTRLNQTVARIPSLSNRLSYAIRKVHTIKGLMARKVSLAQLRLQSCPPPPPAPPVDADLSLELEHLREERNRLDAELQLSAHIIQQEVGRAREQGEAERLQLNEVAQQLEQELQRAQESLVNVGQQLESARQGQQESTEEAANLRQELTQQQQIYGQALQEKVAEVETRLREQLSDTKRRLNEARREQAKAVVSLRQIQHRATREKERNQELRRLQDEARKEEAQRVARRVQELERDKNLMLATLRQEGLLSRYKQQRLLAMLPLGTDKKTVRFSPQPEVSPEHGCPAASPPRECTKESLTALFENLQGLSEAISREEATCPEDKQYTQCPPSDCC", "length": 778, "header": "tr|A0A9J7J2E0-1|A0A9J7J2E0_CRIGR Computationally mapped isoform of Coiled-coil alpha-helical rod protein 1 OS=Cricetulus griseus OX=10029 GN=Cchcr1 PE=4 SV=1 CANONICAL=A0A9J7J4T7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J4T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7/entry#A0A9J7J4T7-1", "sequence": { "sequence": "MRREGPSISRPPPFLIGLQVSRVPGMGRGRQGAEKAWRSQCACVRRSSSFLLPAGGASWGFRASRQPHPPRACVLRAGSLAGKPGAKGRGKKADLALGNDPEIMARWCLDGFPNVPTIPWRELWRRGSQQARSPPDQSYRDRRHLRRKGNLHSCGQDREASDRVEMLSPSGFAGLVPPSHFQARPRMAPTWASDIPQFQSTFDQDVLERRQLDSQRPTVTMREQDVYGDGQGPGQRGRSLELRVSGALSQQAELISRQLQELRRLEEEVRMLRETSLQQKMRLEAQAMEMDALAVAEKAGQAEAEGLRAALAGAEMVRKNLEEGNQRELQEIQTLHQEQLSSMTQAHEMALASLTSKAEGLERALNSLEMKRAGEIKQLSVAQKETELLRGQLSKTQEELEAQVTLVESLRKYVGEQVPPEVHRQAWEPEREELLDTVQHLREDRADLQATVELLQVRVQSLTHMLALQEEELTRKIQPSDVLEPEYPKKCRSLLSSWREKVFVLMVQLKAQDLEHRDSMKGLRDQVAELQEQVMAQSQEQAILQQALQDKAAELEVERMSIKTLQMELNRAQEARRRQKQRTDSVEEQLKFVVSAMKSTQDSIHGTMTRLNQTVARIPSLSNRLSYAIRKVHTIKGLMARKVSLAQLRLQSCPPPPPAPPVDADLSLELEHLREERNRLDAELQLSAHIIQQEVGRAREQGEAERLQLNEVAQQLEQELQRAQESLVNVGQQLESARQGQQESTEEAANLRQELTQQQQIYGQALQEKVAEVETRLREQLSDTKRRLNEARREQAKAVVSLRQIQHRATREKERNQELRRLQDEARKEEAQRVARRVQELERDKNLMLATLRQEGLLSRYKQQRLLAMLPLGTDKKTVRFSPQPEVSPEHGCPAASPPRECTKESLTALFENLQGLSEAISREEATCPEDKQYTQCPPSDCC", "length": 943, "header": "tr|A0A9J7J4T7-1|A0A9J7J4T7_CRIGR Isoform 1 of Coiled-coil alpha-helical rod protein 1 OS=Cricetulus griseus OX=10029 GN=Cchcr1 PE=4 SV=1 CANONICAL=A0A9J7J4T7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EY17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY17" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EY17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY17" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754418", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754418", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J4T7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J4T7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J4T7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J4T7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7" } ], "pmid": "" }, { "name": "protein export from nucleus", "id": "GO:0006611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006611", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J4T7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4T7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 612, "end_pos": 614, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 612, "end_pos": 614 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J7L4-1", "uniprot_ac": "A0A9J7J7L4", "uniprot_id": "A0A9J7J7L4_CRIGR", "mass": { "chemical_mass": 91610.0, "monoisotopic_mass": 91610.0 }, "refseq": { "ac": "XP_027241865", "name": "N-acetylneuraminate 9-O-acetyltransferase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241865" }, "gene_names": [ { "name": "Casd1", "type": "recommended", "evidence": [ { "id": "A0A9J7J7L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4" } ] }, { "name": "Casd1", "type": "synonym", "evidence": [ { "id": "XP_027241865", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241865" } ] } ], "protein_names": [ { "name": "N-acetylneuraminate (7)9-O-acetyltransferase", "type": "recommended", "evidence": [ { "id": "A0A9J7J7L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.45", "type": "synonym", "evidence": [ { "id": "A0A9J7J7L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4/entry#names_and_taxonomy" } ] }, { "name": "CAS1 domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A9J7J7L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4/entry#names_and_taxonomy" } ] }, { "name": "CAS1 protein", "type": "synonym", "evidence": [ { "id": "A0A9J7J7L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4/entry#names_and_taxonomy" } ] }, { "name": "N-acetylneuraminate 9-O-acetyltransferase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027241865", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241865" } ] }, { "name": "Sialate O-acetyltransferase", "type": "synonym", "evidence": [ { "id": "A0A9J7J7L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 223 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613638.1) and transcript sequence (IACG01063337.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027241865.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027241865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241865" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7L4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Casd1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4", "locus": {} } ], "crossref": [ { "id": "A0A9J7J7L4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J7L4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100766850", "url": "https://www.ncbi.nlm.nih.gov/gene/100766850", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012419", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012419", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766850", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766850", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7J7L4", "url": "https://www.orthodb.org/?gene=A0A9J7J7L4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13533", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13533", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13533:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13533:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027241865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241865", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "79499", "url": "https://www.rhea-db.org/rhea/79499", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79555", "url": "https://www.rhea-db.org/rhea/79555", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "81827", "url": "https://www.rhea-db.org/rhea/81827", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7EYE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EYE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2Q7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7L4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALAYNLGKREINHYFSVRSAKVLALVAVLLLAACHLASRRYRGNDSCEYLLSSGRFLGEKVWQPHSCMMHKYKMSEAKNCLVDKHIAFIGDSRIRQLFYSFVKIINPQFKEEGNKHENIPFQDKTSSVKVDFLWHPEVNGSMKQCIKVWTEDLGAKPHVIVAGAATWSIKIHNGSDEALSQYKMNITSIAPLLEKLAKTSDVYWVLQDPVYEDLLSENRKMITNEKIDAYNEAAVSILNSSARNSKSSIKLFSVSKLIAQETIMESLDGLHLPESSRETSAMILMNVYCNKVLKPVDGSCCQPRPPLTLIQKLAACFFTLSIIGYFIFYVIHRNAHRKNKPCTDLESGEEKKNIINTPVSSLEILLQSFCKLGLIMAYFYMCDRANLFMKENKFYTHSSFFIPIIYILVLGVFYNENTKETKVLNREQTDEWKGWMQLVILIYHISGASTFLPVYMHIRVLVAAYLFQTGYGHFSYFWIKGDFGIYRVCQVLFRLNFLVVVLCLVMDRPYQFYYFVPLVTVWFMVIYVTLALWPQIIQKKANGNCLWHLGLLLKLAFLLLCICFLAYSQGAFEKIFSLWPLSKCFELNGNVYEWWFRWRLDRYVVFHGMLFAFIYLALQRWQILSEGKGEPLFSTKISTFLLFISVVSFLTYSIWASSCKNKAQCNELHPSVSVVQIVAFILIRNIPGYARSVYSSFFAWFGKISLELFICQYHIWLAADTRGILVLIPGNPTLNIIISTFIFVCVAHEISQITTDLAQVLIPKDNPSLFRRLACTVAFFCGLLILSSIQDKSRL", "length": 797, "header": "tr|A0A9J7J7L4-1|A0A9J7J7L4_CRIGR Isoform 1 of N-acetylneuraminate (7)9-O-acetyltransferase OS=Cricetulus griseus OX=10029 GN=Casd1 PE=3 SV=1 CANONICAL=A0A9J7J7L4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7EYE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4/entry#A0A9J7EYE3-1", "sequence": { "sequence": "MAALAYNLGKREINHYFSVRSAKVLALVAVLLLAACHLASRRYRGNDSCEYLLSSGRFLGEKVWQPHSCMMHKYKMSEAKNCLVDKHIAFIGDSRIRQLFYSFVKIINPQFKEEGNKHENIPFQDKTSSVKVDFLWHPEVNGSMKQCIKVWTEWSIKIHNGSDEALSQYKMNITSIAPLLEKLAKTSDVYWVLQDPVYEDLLSENRKMITNEKIDAYNEAAVSILNSSARNSKSSIKLFSVSKLIAQETIMESLDGLHLPESSRETSAMILMNVYCNKVLKPVDGSCCQPRPPLTLIQKLAACFFTLSIIGYFIFYVIHRNAHRKNKPCTDLESGEEKKNIINTPVSSLEILLQSFCKLGLIMAYFYMCDRANLFMKENKFYTHSSFFIPIIYILVLGVFYNENTKETKVLNREQTDEWKGWMQLVILIYHISGASTFLPVYMHIRVLVAAYLFQTGYGHFSYFWIKGDFGIYRVCQVLFRLNFLVVVLCLVMDRPYQFYYFVPLVTVWFMVIYVTLALWPQIIQKKANGNCLWHLGLLLKLAFLLLCICFLAYSQGAFEKIFSLWPLSKCFELNGNVYEWWFRWRLDRYVVFHGMLFAFIYLALQRWQILSEGKGEPLFSTKISTFLLFISVVSFLTYSIWASSCKNKAQCNELHPSVSVVQIVAFILIRNIPGYARSVYSSFFAWFGKISLELFICQYHIWLAADTRGILVLIPGNPTLNIIISTFIFVCVAHEISQITTDLAQVLIPKDNPSLFRRLACTVAFFCGLLILSSIQDKSRL", "length": 782, "header": "tr|A0A9J7EYE3-1|A0A9J7J7L4_CRIGR Computationally mapped isoform of N-acetylneuraminate (7)9-O-acetyltransferase OS=Cricetulus griseus OX=10029 GN=Casd1 PE=3 SV=1 CANONICAL=A0A9J7J7L4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F2Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4/entry#A0A9J7F2Q7-1", "sequence": { "sequence": "MAALAYNLGKREINHYFSVRSAKVLALVAVLLLAACHLASRRYRGNDSCEYLLSSGRFLGEKVWQPHSCMMHKYKMSEAKNCLVDKHIAFIGDSRIRQLFYSFVKIINPQFKEEGNKHENIPFQDKTSSVKVDFLWHPEVNGSMKQCIKVWTEDLGAKPHVIVAGAATWSIKIHNGSDEALSQYKMNITSIAPLLEKLAKTSDVYWVLQDPVYEDLLSENRKMITNEKIDAYNEAAVSILNSSARNSKSSIKLFSVSKLIAQETIMESLDGLHLPESSRETSAMILMNVYCNKVLKPVDGSCCQPRPPLTLIQKLAACFFTLSIIGYFIFYVIHRNAHRKNKPCTDLESGEEKKNIINTPVSSLEILLQSFCKLGLIMAYFYMCDRANLFMKENKFYTHSSFFIPIIYILVLGVFYNENTKETKVLNREQTDEWKGWMQLVILIYHISGASTFLPVYMHIRVLVAAYLFQTGYGHFSYFWIKGDFGIYRVCQVLFRLNFLVVVLCLVMDRPYQFYYFVPLVTVWFMVIYVTLALWPQIIQKKANGNCLWHLGLLLKLAFLLLCICFLAYSQGAFEKIFSLWPLSKCFELNGNVYEWWFRWRLDRYTYSIWASSCKNKAQCNELHPSVSVVQIVAFILIRNIPGYARSVYSSFFAWFGKISLELFICQYHIWLAADTRGILVLIPGNPTLNIIISTFIFVCVAHEISQITTDLAQVLIPKDNPSLFRRLACTVAFFCGLLILSSIQDKSRL", "length": 750, "header": "tr|A0A9J7F2Q7-1|A0A9J7J7L4_CRIGR Computationally mapped isoform of N-acetylneuraminate (7)9-O-acetyltransferase OS=Cricetulus griseus OX=10029 GN=Casd1 PE=3 SV=1 CANONICAL=A0A9J7J7L4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J7L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4/entry#A0A9J7J7L4-1", "sequence": { "sequence": "MAALAYNLGKREINHYFSVRSAKVLALVAVLLLAACHLASRRYRGNDSCEYLLSSGRFLGEKVWQPHSCMMHKYKMSEAKNCLVDKHIAFIGDSRIRQLFYSFVKIINPQFKEEGNKHENIPFQDKTSSVKVDFLWHPEVNGSMKQCIKVWTEDLGAKPHVIVAGAATWSIKIHNGSDEALSQYKMNITSIAPLLEKLAKTSDVYWVLQDPVYEDLLSENRKMITNEKIDAYNEAAVSILNSSARNSKSSIKLFSVSKLIAQETIMESLDGLHLPESSRETSAMILMNVYCNKVLKPVDGSCCQPRPPLTLIQKLAACFFTLSIIGYFIFYVIHRNAHRKNKPCTDLESGEEKKNIINTPVSSLEILLQSFCKLGLIMAYFYMCDRANLFMKENKFYTHSSFFIPIIYILVLGVFYNENTKETKVLNREQTDEWKGWMQLVILIYHISGASTFLPVYMHIRVLVAAYLFQTGYGHFSYFWIKGDFGIYRVCQVLFRLNFLVVVLCLVMDRPYQFYYFVPLVTVWFMVIYVTLALWPQIIQKKANGNCLWHLGLLLKLAFLLLCICFLAYSQGAFEKIFSLWPLSKCFELNGNVYEWWFRWRLDRYVVFHGMLFAFIYLALQRWQILSEGKGEPLFSTKISTFLLFISVVSFLTYSIWASSCKNKAQCNELHPSVSVVQIVAFILIRNIPGYARSVYSSFFAWFGKISLELFICQYHIWLAADTRGILVLIPGNPTLNIIISTFIFVCVAHEISQITTDLAQVLIPKDNPSLFRRLACTVAFFCGLLILSSIQDKSRL", "length": 797, "header": "tr|A0A9J7J7L4-1|A0A9J7J7L4_CRIGR Isoform 1 of N-acetylneuraminate (7)9-O-acetyltransferase OS=Cricetulus griseus OX=10029 GN=Casd1 PE=3 SV=1 CANONICAL=A0A9J7J7L4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EYE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYE3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EYE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYE3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766850", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766850", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7L4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7L4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "N-acetylneuraminate 9-O-acetyltransferase activity", "id": "GO:0047186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047186", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7L4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "79499", "name": "", "equation": "a ganglioside GD3 (d18:1(4E)) + acetyl-CoA = a ganglioside Ac-O-7-GD3(d18:1(4E)) + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7J7L4-1" ], "evidence": [ { "id": "79499", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79499" } ] }, { "id": "79555", "name": "", "equation": "CMP-N-acetyl-beta-neuraminate + acetyl-CoA = CMP-N-acetyl-7-O-acetyl-beta-neuraminate + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7J7L4-1" ], "evidence": [ { "id": "79555", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79555" } ] }, { "id": "81827", "name": "", "equation": "CMP-N-acetyl-beta-neuraminate + acetyl-CoA = CMP-N-acetyl-9-O-acetyl-beta-neuraminate + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7J7L4-1" ], "evidence": [ { "id": "81827", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81827" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7J7L4", "gene_name": "Casd1", "activity": [ { "ec_number": "2.3.1.45", "activity": "CMP-N-acetyl-beta-neuraminate + acetyl-CoA = CMP-N-acetyl-9-O-acetyl-beta-neuraminate + CoA.", "evidence": [ { "id": "A0A9J7J7L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4" } ] }, { "ec_number": "2.3.1.45", "activity": "", "evidence": [ { "id": "A0A9J7J7L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J7L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7L4" }, { "id": "PF07779", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07779" } ], "ann_type": 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NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EYW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYW6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"https://www.orthodb.org/?gene=A0A9J7HE79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05986", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05986", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19236", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19236", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309087", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309087", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7F004", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F004", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F004-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F004-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HE79", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HE79-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE79-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLCALLPCLLPWYCTLCAAAGSQTPDLHLSGKLRDYVVTVPCSTDFRGRFLSHVVSAPTIASSHSHLRVARSPLRLEKETLRPGGARHRFLYFNVTVFGKLLHLSLQPNRRLVAPGAPVEWQEDFQELFRQPLQHECVYTGGVTGMPGAAVAISNCDGLAGLIRTDSSDYFIEPLERGQQEEEAGGRTHVVYRREAVQQEWAEPHGDLHNEAFGLGDLPNVLDLVGDQLGDTERKRRHAKPGSYSIEVLLAVDDSVVRFHGKEHTQNYVLTLMNIVDEIYHDESLGAHVNIALVRLIMVGYRQSLSLIERGNPARSLEQVCRWAHSQQRQDPSHTEHHDHVIFLTRQNFGPSGMQGTVLTMARWYAPVTGMCHPLRSCALNHEDGFSSAFVVAHETGHVLGMEHDGQGNGCDDETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFERTWPQPPELPGIDYSMDEQCRFDFGTGYHTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCDNPPPAYGGRPCTGPMFEYQICNSEDCPGPYEDFRAQQCAKRNSYYIHQNAKHSWLPYEPDDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPFGCDKEVGSMKADDKCGVCGGDNSHCRTVKGTLGKATKQAAALKQVQIPAGARHIQIELLEKAPHRIAVKNQVTGSFILNPKGKEASSRTFTALGLEWEHAAEDTKDNLKTSGPLPEAITVLVLPPAEGKPRRSLAYKYVIHEDLLPLIGSNNVLLEETDTYEWALKSWSPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHQKRPKPIRRRCNQHPCPQPTWVAEEWGACSRSCGKLGLQTRGVQCLLPLSNGTRKAMPAKACLGNRPEAKRPCLRVPCPAQWRTGAWSQCSATCGEGIQQRQVVCRNISNTLGQCEGVKPDTVQVCSLPACGGDLQNSTVKAEVQYPVTKVGHWEPQSRLLTPTNRISTMEPCVGDRSIFCRMKVLDRYCTIPGYHRLCCESCTKKTSGPSASPASLATFSTPGSPLPEPKATQEDMKSTRGPTRVEDRRQSHPTQLPGLADRISSGTQHPFTPQMQSPSTFEGNSPATPPPSGWTQTAVPDSAGQGQSKEEPGHGGTSLPATSPVT", "length": 1215, "header": "tr|A0A9J7HE79-1|A0A9J7HE79_CRIGR Isoform 1 of A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X2 OS=Cricetulus griseus OX=10029 GN=Adamts14 PE=4 SV=1 CANONICAL=A0A9J7HE79-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F004-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE79/entry#A0A9J7F004-1", "sequence": { "sequence": "MARLCALLPCLLPWYCTLCAAAGSQTPDLHLSGKLRDYVVTVPCSTDFRGRFLSHVVSAPTIASSHSHLRVARSPLRLEKETLRPGGARHRFLYFNVTVFGKLLHLSLQPNRRLVAPGAPVEWQEDFQELFRQPLQHECVYTGGVTGMPGAAVAISNCDGLAGLIRTDSSDYFIEPLERGQQEEEAGGRTHVVYRREAVQQEWAEPHGDLHNEAFGLGDLPNVLDLVGDQLGDTERKRRHAKPGSYSIEVLLAVDDSVVRFHGKEHTQNYVLTLMNIVDEIYHDESLGAHVNIALVRLIMVGYRQSLSLIERGNPARSLEQVCRWAHSQQRQDPSHTEHHDHVIFLTRQNFGPSGYAPVTGMCHPLRSCALNHEDGFSSAFVVAHETGHVLGMEHDGQGNGCDDETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFERTWPQPPELPGIDYSMDEQCRFDFGTGYHTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCDNPPPAYGGRPCTGPMFEYQICNSEDCPGPYEDFRAQQCAKRNSYYIHQNAKHSWLPYEPDDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPFGCDKEVGSMKADDKCGVCGGDNSHCRTVKGTLGKATKQAAALKQVQIPAGARHIQIELLEKAPHRIAVKNQVTGSFILNPKGKEASSRTFTALGLEWEHAAEDTKDNLKTSGPLPEAITVLVLPPAEGKPRRSLAYKYVIHEDLLPLIGSNNVLLEETDTYEWALKSWSPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHQKRPKPIRRRCNQHPCPQPTWVAEEWGACSRSCGKLGLQTRGVQCLLPLSNGTRKAMPAKACLGNRPEAKRPCLRVPCPAQWRTGAWSQCSATCGEGIQQRQVVCRNISNTLGQCEGVKPDTVQVCSLPACGGDLQNSTVKAEVQYPVTKVGHWEPQSRLLTPTNRISTMEPCVGDRSIFCRMKVLDRYCTIPGYHRLCCESCTKKTSGPSASPASLATFSTPGSPLPEPKATQEDMKSTRGPTRVEDRRQSHPTQLPGLADRISSGTQHPFTPQMQSPSTFEGNSPATPPPSGWTQTAVPDSAGQGQSKEEPGHGGTSLPATSPVT", "length": 1204, "header": "tr|A0A9J7F004-1|A0A9J7HE79_CRIGR Computationally mapped isoform of A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X2 OS=Cricetulus griseus OX=10029 GN=Adamts14 PE=4 SV=1 CANONICAL=A0A9J7HE79-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HE79-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE79/entry#A0A9J7HE79-1", "sequence": { "sequence": "MARLCALLPCLLPWYCTLCAAAGSQTPDLHLSGKLRDYVVTVPCSTDFRGRFLSHVVSAPTIASSHSHLRVARSPLRLEKETLRPGGARHRFLYFNVTVFGKLLHLSLQPNRRLVAPGAPVEWQEDFQELFRQPLQHECVYTGGVTGMPGAAVAISNCDGLAGLIRTDSSDYFIEPLERGQQEEEAGGRTHVVYRREAVQQEWAEPHGDLHNEAFGLGDLPNVLDLVGDQLGDTERKRRHAKPGSYSIEVLLAVDDSVVRFHGKEHTQNYVLTLMNIVDEIYHDESLGAHVNIALVRLIMVGYRQSLSLIERGNPARSLEQVCRWAHSQQRQDPSHTEHHDHVIFLTRQNFGPSGMQGTVLTMARWYAPVTGMCHPLRSCALNHEDGFSSAFVVAHETGHVLGMEHDGQGNGCDDETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFERTWPQPPELPGIDYSMDEQCRFDFGTGYHTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCDNPPPAYGGRPCTGPMFEYQICNSEDCPGPYEDFRAQQCAKRNSYYIHQNAKHSWLPYEPDDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPFGCDKEVGSMKADDKCGVCGGDNSHCRTVKGTLGKATKQAAALKQVQIPAGARHIQIELLEKAPHRIAVKNQVTGSFILNPKGKEASSRTFTALGLEWEHAAEDTKDNLKTSGPLPEAITVLVLPPAEGKPRRSLAYKYVIHEDLLPLIGSNNVLLEETDTYEWALKSWSPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHQKRPKPIRRRCNQHPCPQPTWVAEEWGACSRSCGKLGLQTRGVQCLLPLSNGTRKAMPAKACLGNRPEAKRPCLRVPCPAQWRTGAWSQCSATCGEGIQQRQVVCRNISNTLGQCEGVKPDTVQVCSLPACGGDLQNSTVKAEVQYPVTKVGHWEPQSRLLTPTNRISTMEPCVGDRSIFCRMKVLDRYCTIPGYHRLCCESCTKKTSGPSASPASLATFSTPGSPLPEPKATQEDMKSTRGPTRVEDRRQSHPTQLPGLADRISSGTQHPFTPQMQSPSTFEGNSPATPPPSGWTQTAVPDSAGQGQSKEEPGHGGTSLPATSPVT", "length": 1215, "header": "tr|A0A9J7HE79-1|A0A9J7HE79_CRIGR Isoform 1 of A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X2 OS=Cricetulus griseus OX=10029 GN=Adamts14 PE=4 SV=1 CANONICAL=A0A9J7HE79-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1177, "start_aa": "Thr", "end_pos": 1177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1177", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F004", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F004" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F004", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F004" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768329", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768329", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE79", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE79" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE79", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE79" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE79", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE79" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE79", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE79" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE79", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE79" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1025, "end_pos": 1027, "annotation": "n_glycosylation_sequon" }, { "start_pos": 939, "end_pos": 941, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" }, { "start_pos": 995, "end_pos": 997, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HE79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE79" }, { "id": "PS50900", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50900" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PLAC", "eco_id": "ECO_0000259", "start_pos": 1057, "end_pos": 1095, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7HE79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE79" }, { "id": "PS50215", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50215" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M12B", "eco_id": "ECO_0000259", "start_pos": 246, "end_pos": 458, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A9J7F004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F004#function" }, { "id": "A0A9J7F004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F004" }, { "id": "PIRSR613273-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR613273-2" }, { "id": "A0A9J7HE79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE79#function" }, { "id": "A0A9J7HE79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE79" } ], "binding_site_uniprot": 249, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_29108", "ligand": "Ca(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 249, "end_pos": 249, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7F004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F004#function" }, { "id": "A0A9J7F004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F004" }, { "id": "PIRSR613273-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR613273-2" }, { "id": "A0A9J7HE79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE79#function" }, { "id": "A0A9J7HE79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE79" } ], "binding_site_uniprot": 341, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_29108", "ligand": "Ca(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 341, "end_pos": 341, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7F004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F004#function" }, { "id": "A0A9J7F004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F004" }, { "id": "PIRSR613273-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR613273-2" }, { "id": "PRU00276", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00276" } ], "binding_site_uniprot": 385, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 385, "end_pos": 385, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7F004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F004#function" }, { "id": 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record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615432.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 18, 2018 this sequence version replaced XP_003512417.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003512417", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512417" } ] }, { "annotation": "Promotes the growth of epithelial cells. 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"MKYKWRKDSESTIKNPPPFCLGGPVKEVQQLQDMALGVAMAVCLLFKAMATALTEEAEVHVIPPSLEQQSNGTVNDTEADYIEGPVALKFSHPCLEDHNNYCINGVCAFHHELKKAICRCLNLKSPYIICSGGRPL", "length": 136, "header": "tr|A0A9J7J6I4-1|A0A9J7J6I4_CRIGR Computationally mapped isoform of Epigen isoform X4 OS=Cricetulus griseus OX=10029 GN=Epgn PE=4 SV=1 CANONICAL=A0A9J7J4P3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J6N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4P3/entry#A0A9J7J6N5-1", "sequence": { "sequence": "MKYKWRKDSESTIKNPPPFCLGGPVKEVQQLQDMALGVAMAVCLLFKAMATALTEEAEVHVIPPSLEQQTDYIEGPVALKFSHPCLEDHNNYCINGVCAFHHELKKAICRCLNLKSPYIICSGGRPL", "length": 127, "header": "tr|A0A9J7J6N5-1|A0A9J7J6N5_CRIGR Computationally mapped isoform of Epigen isoform X5 OS=Cricetulus griseus OX=10029 GN=Epgn PE=4 SV=1 CANONICAL=A0A9J7J4P3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F088", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F088" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F088", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F088" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771437", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771437", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J4P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4P3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J4P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4P3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J4P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4P3" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J4P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4P3" } ], "pmid": "" }, { "name": "epidermal growth factor receptor signaling pathway", "id": "GO:0007173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007173", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J4P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4P3" } ], "pmid": "" }, { "name": "positive regulation of mitotic nuclear division", 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"total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J8S3-1", "uniprot_ac": "A0A9J7J8S3", "uniprot_id": "A0A9J7J8S3_CRIGR", "mass": { "chemical_mass": 64579.0, "monoisotopic_mass": 64579.0 }, "refseq": { "ac": "XP_027247454", "name": "eukaryotic translation initiation factor 2A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247454" }, "gene_names": [ { "name": "Eif2a", "type": "recommended", "evidence": [ { "id": "A0A9J7J8S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8S3" } ] }, { "name": "Eif2a", "type": "synonym", "evidence": [ { "id": "XP_027247454", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247454" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 2A", "type": "recommended", "evidence": [ { "id": "A0A9J7J8S3", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027247454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247454" } ] }, { "annotation": "Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F0U0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0U0#function" }, { "database": "UniProtKB", "id": "ARBA00003993", "url": "https://www.uniprot.org/uniprotkb/ARBA00003993#function" }, { "database": "UniProtKB", "id": "PIRNR017222", "url": "https://www.uniprot.org/uniprotkb/PIRNR017222#function" }, { "database": "UniProtKB", "id": "A0A9J7F4Z2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4Z2#function" }, { "database": "UniProtKB", "id": "A0A9J7J8S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8S3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8S3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Eif2a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8S3", "locus": {} } ], "crossref": [ { "id": "A0A9J7J8S3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J8S3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100767762", "url": "https://www.ncbi.nlm.nih.gov/gene/100767762", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767762", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767762", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7J8S3", "url": "https://www.orthodb.org/?gene=A0A9J7J8S3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13227", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13227", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13227:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13227:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027247454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247454", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7F0U0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F0U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0U0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F4Z2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F4Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8S3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPSTPLLTVRGSEGLYMVNGPPHFTESTVLPRESGKNCKVYTFSKDGTLFAWNNGEKVNILNVTNKGLLHSFDVPKAVCLEFSPNNTVLATWQPYTTSKDGTAGVPNLQLYDVKTGTCLKSFIQKKMQNWCPSWSDDEIICARNVNNEVHFFENNNFNTIANKLHLQKVNDFNLSPGSQPYKVAVYVPGSKGAPSFVRLYQYPNFAGPQAALANKSFFKADKVTMLWNKKATAVLVIASTDVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNSGSTEFCAVYGFMPAKATVFNLKCDPVFDFGTGPRNAAFYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDSTYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSLLHKYDVPSNGELWQVSWQPFLDGVFPAKTIMYQAVPSEVPSEEPKVATAYRPPALRNKPVTNSKLHEDEPPQNMKPHPGSDKPLSKTALKNQRKHEAKKAAKQEARSDSASTPVIPQSVPRNTITQSVSGDPEVDKKIKNLKKKLKAIEQLKEQAASGKQLEKNQLEKIQKETALLRELEDLELGI", "length": 582, "header": "tr|A0A9J7J8S3-1|A0A9J7J8S3_CRIGR Isoform 1 of Eukaryotic translation initiation factor 2A OS=Cricetulus griseus OX=10029 GN=Eif2a PE=3 SV=1 CANONICAL=A0A9J7J8S3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F0U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8S3/entry#A0A9J7F0U0-1", "sequence": { "sequence": "MVNGPPHFTESTVLPRESGKNCKVYTFSKDGTLFAWNNGEKVNILNVTNKGLLHSFDVPKAVCLEFSPNNTVLATWQPYTTSKDGTAGVPNLQLYDVKTGTCLKSFIQKKMQNWCPSWSDDEIICARNVNNEVHFFENNNFNTIANKLHLQKVNDFNLSPGSQPYKVAVYVPGSKGAPSFVRLYQYPNFAGPQAALANKSFFKADKVTMLWNKKATAVLVIASTDVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNSGSTEFCAVYGFMPAKATVFNLKCDPVFDFGTGPRNAAFYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDSTYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSLLHKYDVPSNGELWQVSWQPFLDGVFPAKTIMYQAVPSEVPSEEPKVATAYRPPALRNKPVTNSKLHEDEPPQNMKPHPGSDKPLSKTALKNQRKHEAKKAAKQEARSDSASTPVIPQSVPRNTITQSVSGDPEVDKKIKNLKKKLKAIEQLKEQAASGKQLEKNQLEKIQKETALLRELEDLELGI", "length": 565, "header": "tr|A0A9J7F0U0-1|A0A9J7J8S3_CRIGR Computationally mapped isoform of Eukaryotic translation initiation factor 2A OS=Cricetulus griseus OX=10029 GN=Eif2a PE=3 SV=1 CANONICAL=A0A9J7J8S3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F4Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8S3/entry#A0A9J7F4Z2-1", "sequence": { "sequence": "MDHHTLQKAQCFQGNLEKIAKSTHLVRMGHCLPGTMEKTSKDGTAGVPNLQLYDVKTGTCLKSFIQKKMQNWCPSWSDDEIICARNVNNEVHFFENNNFNTIANKLHLQKVNDFNLSPGSQPYKVAVYVPGSKGAPSFVRLYQYPNFAGPQAALANKSFFKADKVTMLWNKKATAVLVIASTDVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNSGSTEFCAVYGFMPAKATVFNLKCDPVFDFGTGPRNAAFYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDSTYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSLLHKYDVPSNGELWQVSWQPFLDGVFPAKTIMYQAVPSEVPSEEPKVATAYRPPALRNKPVTNSKLHEDEPPQNMKPHPGSDKPLSKTALKNQRKHEAKKAAKQEARSDSASTPVIPQSVPRNTITQSVSGDPEVDKKIKNLKKKLKAIEQLKEQAASGKQLEKNQLEKIQKETALLRELEDLELGI", "length": 523, "header": "tr|A0A9J7F4Z2-1|A0A9J7J8S3_CRIGR Computationally mapped isoform of Eukaryotic translation initiation factor 2A OS=Cricetulus griseus OX=10029 GN=Eif2a PE=3 SV=1 CANONICAL=A0A9J7J8S3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J8S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8S3/entry#A0A9J7J8S3-1", "sequence": { "sequence": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8K2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8K2" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8K2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8K2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8K2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8K2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8K2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8K2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J8K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8K2" }, { "id": "PS51088", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51088" }, { "id": "PRU00505", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00505" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TEA", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 142, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J5X3-1", "uniprot_ac": "A0A9J7J5X3", "uniprot_id": "A0A9J7J5X3_CRIGR", "mass": { "chemical_mass": 73976.0, "monoisotopic_mass": 73976.0 }, "refseq": { "ac": "XP_003498011", "name": "integrator complex subunit 9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498011" }, "gene_names": [ { "name": "Ints9", "type": "recommended", "evidence": [ { "id": "A0A9J7J5X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X3" } ] }, { "name": "Ints9", "type": "synonym", "evidence": [ { "id": "XP_003498011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498011" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 9", "type": "recommended", "evidence": [ { "id": "A0A9J7J5X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X3/entry#names_and_taxonomy" } ] }, { "name": "integrator complex subunit 9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003498011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498011" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613673.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003498011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498011" } ] }, { "annotation": "Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit POLR2A/RPB1 and SUPT5H/SPT5, (2) degrading the exiting nascent RNA transcript via endonuclease activity and (3) promoting the release of Pol II from bound DNA. The integrator complex is also involved in terminating the synthesis of non-coding Pol II transcripts, such as enhancer RNAs (eRNAs), small nuclear RNAs (snRNAs), telomerase RNAs and long non-coding RNAs (lncRNAs). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the integrator complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F2C6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2C6#function" }, { "database": "UniProtKB", "id": "ARBA00057156", "url": "https://www.uniprot.org/uniprotkb/ARBA00057156#function" }, { "database": "UniProtKB", "id": "A0A9J7J3D7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3D7#function" }, { "database": "UniProtKB", "id": "A0A9J7J5X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ints9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X3", "locus": {} } ], "crossref": [ { "id": "A0A9J7J5X3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J5X3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16294", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16294", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752291", "url": "https://www.ncbi.nlm.nih.gov/gene/100752291", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022712", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022712", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752291", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752291", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7F2C6", "url": "https://www.orthodb.org/?gene=A0A9J7F2C6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J3D7", "url": "https://www.orthodb.org/?gene=A0A9J7J3D7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J5X3", "url": "https://www.orthodb.org/?gene=A0A9J7J5X3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46094", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46094", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46094:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46094:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10996", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10996", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21382", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21382", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003498011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498011", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7F2C6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2C6-1", "url": 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"MKLYCLSGHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSNLPGWSLKDGNAFLDKELKECSGHVFVDSVPEFCLPETELIDLSTVDVILISNYHCMMALPYITEHTGFTGTVYATEPTMQIGRLLMEELVNFIERVPKAQSASLWKNKDIQRLLPSPLKDAVEVSTWRRCYTMQEVNSALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSDVLVLTGLTQIPTANPDGMVGEFCSNLALTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNIPFYFISPVANSSLEFSQIFAEWLCHNKQSKVYLPEPPFPHAELIQTNKLKHYPSIHGDFSNDFRQPCVVFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLEALAPYQPLAMKCIYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPAQSHRMDLMIDCQPPAMSYRRAEVLALPFKRRYEKIEIMPELADSLVPMEIKPGISLATVSAVLHTKDNKHVLQPPPRPTQPPSSKKRKRVSEDVPDCKVLKPLLSGSIPVEQFVQTLEKHGFSDIKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDETLRVRLRDLVLRFLQKF", "length": 658, "header": "tr|A0A9J7J5X3-1|A0A9J7J5X3_CRIGR Isoform 1 of Integrator complex subunit 9 OS=Cricetulus griseus OX=10029 GN=Ints9 PE=3 SV=1 CANONICAL=A0A9J7J5X3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F2C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X3/entry#A0A9J7F2C6-1", "sequence": { "sequence": "MLDCGLDMTSTLNFLPLPLVQSPRLSNLPGWSLKDGNAFLDKELKECSGHVFVDSVPEFCLPETELIDLSTVDVILISNYHCMMALPYITEHTGFTGTVYATEPTMQIGRLLMEELVNFIERVPKAQSASLWKNKDIQRLLPSPLKDAVEVSTWRRCYTMQEVNSALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSDVLVLTGLTQIPTANPDGMVGEFCSNLALTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNIPFYFISPVANSSLEFSQIFAEWLCHNKQSKVYLPEPPFPHAELIQTNKLKHYPSIHGDFSNDFRQPCVVFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLEALAPYQPLAMKCIYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPAQSHRMDLMIDCQPPAMSYRRAEVLALPFKRRYEKIEIMPELADSLVPMEIKPGISLATVSAVLHTKDNKHVLQPPPRPTQPPSSKKRKRVSEDVPDCKVLKPLLSGSIPVEQFVQTLEKHGFSDIKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDETLRVRLRDLVLRFLQKF", "length": 634, "header": "tr|A0A9J7F2C6-1|A0A9J7J5X3_CRIGR Computationally mapped isoform of Integrator complex subunit 9 OS=Cricetulus griseus OX=10029 GN=Ints9 PE=3 SV=1 CANONICAL=A0A9J7J5X3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J3D7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X3/entry#A0A9J7J3D7-1", "sequence": { "sequence": "MMALPYITEHTGFTGTVYATEPTMQIGRLLMEELVNFIERVPKAQSASLWKNKDIQRLLPSPLKDAVEVSTWRRCYTMQEVNSALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSDVLVLTGLTQIPTANPDGMVGEFCSNLALTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNIPFYFISPVANSSLEFSQIFAEWLCHNKQSKVYLPEPPFPHAELIQTNKLKHYPSIHGDFSNDFRQPCVVFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLEALAPYQPLAMKCIYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPAQSHRMDLMIDCQPPAMSYRRAEVLALPFKRRYEKIEIMPELADSLVPMEIKPGISLATVSAVLHTKDNKHVLQPPPRPTQPPSSKKRKRVSEDVPDCKVLKPLLSGSIPVEQFVQTLEKHGFSDIKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDETLRVRLRDLVLRFLQKF", "length": 552, "header": "tr|A0A9J7J3D7-1|A0A9J7J3D7_CRIGR Computationally mapped isoform of Integrator complex subunit 9 OS=Cricetulus griseus OX=10029 GN=Ints9 PE=3 SV=1 CANONICAL=A0A9J7J5X3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J5X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X3/entry#A0A9J7J5X3-1", "sequence": { "sequence": "MKLYCLSGHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSNLPGWSLKDGNAFLDKELKECSGHVFVDSVPEFCLPETELIDLSTVDVILISNYHCMMALPYITEHTGFTGTVYATEPTMQIGRLLMEELVNFIERVPKAQSASLWKNKDIQRLLPSPLKDAVEVSTWRRCYTMQEVNSALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSDVLVLTGLTQIPTANPDGMVGEFCSNLALTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNIPFYFISPVANSSLEFSQIFAEWLCHNKQSKVYLPEPPFPHAELIQTNKLKHYPSIHGDFSNDFRQPCVVFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLEALAPYQPLAMKCIYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPAQSHRMDLMIDCQPPAMSYRRAEVLALPFKRRYEKIEIMPELADSLVPMEIKPGISLATVSAVLHTKDNKHVLQPPPRPTQPPSSKKRKRVSEDVPDCKVLKPLLSGSIPVEQFVQTLEKHGFSDIKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDETLRVRLRDLVLRFLQKF", "length": 658, "header": "tr|A0A9J7J5X3-1|A0A9J7J5X3_CRIGR Isoform 1 of Integrator complex subunit 9 OS=Cricetulus griseus OX=10029 GN=Ints9 PE=3 SV=1 CANONICAL=A0A9J7J5X3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 560, "start_aa": "Thr", "end_pos": 560, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr560", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F2C6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2C6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F2C6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2C6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752291", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752291", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X3" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X3" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway", "id": "GO:0090101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090101", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X3" } ], "pmid": "" }, { "name": "regulation of cellular response to growth factor stimulus", "id": "GO:0090287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090287", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X3" } ], "pmid": "" }, { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X3" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J5X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J5X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5X3" }, { "id": "SM01027", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01027" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-Casp", "eco_id": "ECO_0000259", "start_pos": 305, "end_pos": 433, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 560 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 334, "end_pos": 336 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HF17-1", "uniprot_ac": "A0A9J7HF17", "uniprot_id": "A0A9J7HF17_CRIGR", "mass": { "chemical_mass": 102437.0, "monoisotopic_mass": 102437.0 }, "refseq": { "ac": "XP_035305563", "name": "inter-alpha-trypsin inhibitor heavy chain H1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305563" }, "gene_names": [ { "name": "Itih1", "type": "recommended", "evidence": [ { "id": "A0A9J7HF17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF17" } ] }, { "name": "Itih1", "type": "synonym", "evidence": [ { "id": "XP_035305563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305563" } ] } ], "protein_names": [ { "name": "Inter-alpha-trypsin inhibitor heavy chain H1", "type": "recommended", "evidence": [ { "id": "A0A9J7HF17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF17/entry#names_and_taxonomy" } ] }, { "name": "inter-alpha-trypsin inhibitor heavy chain H1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035305563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305563" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613589.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305563" } ] }, { "annotation": "May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F2N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2N4#function" }, { "database": "UniProtKB", "id": "ARBA00037051", "url": "https://www.uniprot.org/uniprotkb/ARBA00037051#function" }, { "database": "UniProtKB", "id": "A0A9J7HF17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF17#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF17" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Itih1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF17", "locus": {} } ], "crossref": [ { "id": "A0A9J7HF17", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HF17", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01461", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01461", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761604", "url": "https://www.ncbi.nlm.nih.gov/gene/100761604", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761604", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761604", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7F2N4", "url": "https://www.orthodb.org/?gene=A0A9J7F2N4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7HF17", "url": "https://www.orthodb.org/?gene=A0A9J7HF17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10338", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10338", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10338:SF106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10338:SF106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06668", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06668", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08487", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08487", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305563", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7F2N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2N4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HF17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HF17-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGAMGLRVLLCLCLVSLLTLQAMPALGLATGRPRGREKRQAVDTVRSPTFLLQTVDGVFIKSLKVNCKVTSRFAHYVITSQVVNSADEAREVAFDVEIPKTAFISDFAITADRNTFIGDIKDKVSAWKQYRKAAILGENAGLVRASGRNMEQFTIHISVGAQSKATFQLTYEEVLKRRLMQYDIVIKVKPKQLVQHFEIDVDIFEPQGISKLDAQASFLSKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCSTCSTSLLNGDFKVTYDVNRDKLCDLLVANNYFAHFFAPQNLTNMSKNLVFVIDISGSMEGQKVKQTKEALLKILGDVKPGDNFDLVLFGSQVQSWKGSLVPATQANLQAAQDFVRRFSLAGATNLNGGLLRGIEILNKAQGSHPELSSPASILIMLTDGEPTEGETDRSQILKNVRNAIRGRFPLYNLGFGHDLDFNFLEVMSMENSGWAQRIYEDHDATQQLQGFYNQVANPLLTDVELQYPQDSVLTLTQHRHKQYYDGSEIVVAGRIADHKLSSFKADVRARGERQEFKATCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKMEGEEKANLSSQVLKMSLDYQFVTPLTSMTIRGLTDQDGLEPTIDKTPEDSQPLEMVGPRRTFVLSATQPSPTARTSIVSKLPNQVTGVDTDPHFIIYVPQKEDSLCFNINEEPGVILSLVQDPDTGFSVNGQLVGNKASRPGQPEGTYFGRFGISNPASDFQLEVTPQNITLNPSSGGPVFSWRDQATLQKDGVIVTINKKRNLVVSVEDGATFEIVLHRTWKGSAVHQDFLGFYVLNSFQMSARTQGLLGQFFYPLDFEVSDIRPGSDPMKLDATMVVKNQQLTVTRGLQRDYSKDSRHGTEVSCWFIHNNGAGLIDGVHTDYIVPDIF", "length": 919, "header": "tr|A0A9J7HF17-1|A0A9J7HF17_CRIGR Isoform 1 of Inter-alpha-trypsin inhibitor heavy chain H1 OS=Cricetulus griseus OX=10029 GN=Itih1 PE=3 SV=1 CANONICAL=A0A9J7HF17-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F2N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF17/entry#A0A9J7F2N4-1", "sequence": { "sequence": "MDGAMGLRVLLCLCLVSLLTLQAMPALGLATGRPRGREKRQAVDTTVDGVFIKSLKVNCKVTSRFAHYVITSQVVNSADEAREVAFDVEIPKTAFISDFAITADRNTFIGDIKDKVSAWKQYRKAAILGENAGLVRASGRNMEQFTIHISVGAQSKATFQLTYEEVLKRRLMQYDIVIKVKPKQLVQHFEIDVDIFEPQGISKLDAQASFLSKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCSTCSTSLLNGDFKVTYDVNRDKLCDLLVANNYFAHFFAPQNLTNMSKNLVFVIDISGSMEGQKVKQTKEALLKILGDVKPGDNFDLVLFGSQVQSWKGSLVPATQANLQAAQDFVRRFSLAGATNLNGGLLRGIEILNKAQGSHPELSSPASILIMLTDGEPTEGETDRSQILKNVRNAIRGRFPLYNLGFGHDLDFNFLEVMSMENSGWAQRIYEDHDATQQLQGFYNQVANPLLTDVELQYPQDSVLTLTQHRHKQYYDGSEIVVAGRIADHKLSSFKADVRARGERQEFKATCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKMEGEEKANLSSQVLKMSLDYQFVTPLTSMTIRGLTDQDGLEPTIDKTPEDSQPLEMVGPRRTFVLSATQPSPTARTSIVSKLPNQVTGVDTDPHFIIYVPQKEDSLCFNINEEPGVILSLVQDPDTGFSVNGQLVGNKASRPGQPEGTYFGRFGISNPASDFQLEVTPQNITLNPSSGGPVFSWRDQATLQKDGVIVTINKKRNLVVSVEDGATFEIVLHRTWKGSAVHQDFLGFYVLNSFQMSARTQGLLGQFFYPLDFEVSDIRPGSDPMKLDATMVVKNQQLTVTRGLQRDYSKDSRHGTEVSCWFIHNNGAGLIDGVHTDYIVPDIF", "length": 910, "header": "tr|A0A9J7F2N4-1|A0A9J7HF17_CRIGR Computationally mapped isoform of Inter-alpha-trypsin inhibitor heavy chain H1 OS=Cricetulus griseus OX=10029 GN=Itih1 PE=3 SV=1 CANONICAL=A0A9J7HF17-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HF17-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF17/entry#A0A9J7HF17-1", "sequence": { "sequence": "MDGAMGLRVLLCLCLVSLLTLQAMPALGLATGRPRGREKRQAVDTVRSPTFLLQTVDGVFIKSLKVNCKVTSRFAHYVITSQVVNSADEAREVAFDVEIPKTAFISDFAITADRNTFIGDIKDKVSAWKQYRKAAILGENAGLVRASGRNMEQFTIHISVGAQSKATFQLTYEEVLKRRLMQYDIVIKVKPKQLVQHFEIDVDIFEPQGISKLDAQASFLSKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCSTCSTSLLNGDFKVTYDVNRDKLCDLLVANNYFAHFFAPQNLTNMSKNLVFVIDISGSMEGQKVKQTKEALLKILGDVKPGDNFDLVLFGSQVQSWKGSLVPATQANLQAAQDFVRRFSLAGATNLNGGLLRGIEILNKAQGSHPELSSPASILIMLTDGEPTEGETDRSQILKNVRNAIRGRFPLYNLGFGHDLDFNFLEVMSMENSGWAQRIYEDHDATQQLQGFYNQVANPLLTDVELQYPQDSVLTLTQHRHKQYYDGSEIVVAGRIADHKLSSFKADVRARGERQEFKATCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKMEGEEKANLSSQVLKMSLDYQFVTPLTSMTIRGLTDQDGLEPTIDKTPEDSQPLEMVGPRRTFVLSATQPSPTARTSIVSKLPNQVTGVDTDPHFIIYVPQKEDSLCFNINEEPGVILSLVQDPDTGFSVNGQLVGNKASRPGQPEGTYFGRFGISNPASDFQLEVTPQNITLNPSSGGPVFSWRDQATLQKDGVIVTINKKRNLVVSVEDGATFEIVLHRTWKGSAVHQDFLGFYVLNSFQMSARTQGLLGQFFYPLDFEVSDIRPGSDPMKLDATMVVKNQQLTVTRGLQRDYSKDSRHGTEVSCWFIHNNGAGLIDGVHTDYIVPDIF", "length": 919, "header": "tr|A0A9J7HF17-1|A0A9J7HF17_CRIGR Isoform 1 of Inter-alpha-trypsin inhibitor heavy chain H1 OS=Cricetulus griseus OX=10029 GN=Itih1 PE=3 SV=1 CANONICAL=A0A9J7HF17-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F2N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2N4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F2N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2N4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761604", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761604", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF17" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": 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"Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 293, "end_pos": 295 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 596, "end_pos": 598 }, { "start_pos": 758, "end_pos": 760 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J708-1", "uniprot_ac": "A0A9J7J708", "uniprot_id": "A0A9J7J708_CRIGR", "mass": { "chemical_mass": 35777.0, "monoisotopic_mass": 35777.0 }, "refseq": { "ac": "XP_027247759", "name": "nucleoside diphosphate-linked moiety X motif 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247759" }, "gene_names": [ { "name": "Nudt6", "type": "recommended", "evidence": [ { "id": "A0A9J7J708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J708" } ] }, { "name": "Nudt6", "type": 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{ "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027247759", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247759" } ] }, { "annotation": "May contribute to the regulation of cell proliferation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MGB1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MGB1#function" }, { "database": "UniProtKB", "id": "RU368106", "url": "https://www.uniprot.org/uniprotkb/RU368106#function" } ] }, { "annotation": "Mediates the hydrolysis of some nucleoside diphosphate derivatives, such as NADH and FAD (in vitro). May modulate the subcellular levels of redox dinucleotides and control the mitochondrial concentrations of these compounds. May contribute to the regulation of cell proliferation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F490", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F490#function" }, { "database": "UniProtKB", "id": "ARBA00094205", "url": "https://www.uniprot.org/uniprotkb/ARBA00094205#function" }, { "database": "UniProtKB", "id": "A0A9J7J708", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J708#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J708", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J708" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nudt6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J708", "locus": {} } ], "crossref": [ { "id": "A0A9J7J708", "url": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF00293", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18290", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18290", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027247759", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247759", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13889", "url": "https://www.rhea-db.org/rhea/13889", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "48868", "url": "https://www.rhea-db.org/rhea/48868", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MGB1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MGB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MGB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MGB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F490", "url": 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griseus OX=10029 GN=Nudt6 PE=3 SV=1 CANONICAL=A0A9J7J708-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MGB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J708/entry#A0A8C2MGB1-1", "sequence": { "sequence": "MWKFPGGLSEPGEDIGDTAVREVFEETGVKSEFRSLLSIRQQHRNPEAFGKSDMYLICRLQPRSFTINFCQQECLKCEWMDLEKLAKTENTTPITSRVARLLLYGHREGFDKIDLSMEELPAVYTGLFYKLYHRGLPESYRTTMGVD", "length": 147, "header": "tr|A0A8C2MGB1-1|A0A9J7J708_CRIGR Computationally mapped isoform of Nucleoside diphosphate-linked moiety X motif 6 OS=Cricetulus griseus OX=10029 GN=Nudt6 PE=3 SV=1 CANONICAL=A0A9J7J708-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F490-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J708/entry#A0A9J7F490-1", "sequence": { "sequence": "MGKPRSTLAGAAIKRWRSEGRVAAWLHIPILQSHFIAPAASLGFCFHHAESHSSTLTLWLGEGPSRLPGYATHQVGVAGAVFDDSTRKVLVVQDRNKLKNMWKFPGGLSEPGEDIGDTAVREVFEETGVKSEFRSLLSIRQQHRNPEAFGKSDMYLICRLQPRSFTINFCQQECLKCEWMDLEKLAKTENTTPITSRVARLLLYGHREGFDKIDLSMEELPAVYTGLFYKLYHRGLPESYRTTMGVD", "length": 247, "header": "tr|A0A9J7F490-1|A0A9J7J708_CRIGR Computationally mapped isoform of Nucleoside diphosphate-linked moiety X motif 6 OS=Cricetulus griseus OX=10029 GN=Nudt6 PE=3 SV=1 CANONICAL=A0A9J7J708-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J708-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J708/entry#A0A9J7J708-1", "sequence": { "sequence": "MLGATEKLGAAMRWLWRPVGLQAALLRAGGAGFRTEARTASGSPREAGELQGELDRFGGVSVHLARHRALHGLDAAAFRRLLQAAIKRWRSEGRVAAWLHIPILQSHFIAPAASLGFCFHHAESHSSTLTLWLGEGPSRLPGYATHQVGVAGAVFDDSTRKVLVVQDRNKLKNMWKFPGGLSEPGEDIGDTAVREVFEETGVKSEFRSLLSIRQQHRNPEAFGKSDMYLICRLQPRSFTINFCQQECLKCEWMDLEKLAKTENTTPITSRVARLLLYGHREGFDKIDLSMEELPAVYTGLFYKLYHRGLPESYRTTMGVD", "length": 320, "header": "tr|A0A9J7J708-1|A0A9J7J708_CRIGR Isoform 1 of Nucleoside diphosphate-linked moiety X motif 6 OS=Cricetulus griseus OX=10029 GN=Nudt6 PE=3 SV=1 CANONICAL=A0A9J7J708-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027250942", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250942", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LLP1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LLP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LPE1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LPE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F4M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F4M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4M3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F4M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F4M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4M5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F5F5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5F5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F5F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5F5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F706", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F706", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F706-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F706-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F8R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8R8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F8R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8R8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F8Y0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8Y0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F8Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8Y0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F986", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F986", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F986-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F986-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J648", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J648-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J953", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J953", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J953-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J953-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JB53", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JB53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JB53-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JB53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JB61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JB61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JB61-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JB61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JCM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JCM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JCM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JCM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEA9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADYSTVPPPSSGSAGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDGSWTNPSSTAHWEGMPSPFKDQPEAKKVAPQNDSFGAQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPTGAPTTTQTNGQGNYGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQCLPRPSTLGSAAKSNSAEDAASTKS", "length": 686, "header": "tr|A0A9J7J648-1|A0A9J7J648_CRIGR Isoform 1 of Far upstream element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Fubp1 PE=4 SV=1 CANONICAL=A0A9J7J648-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LLP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648/entry#A0A8C2LLP1-1", "sequence": { "sequence": "MADYSTVPPPSSGSAGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDQPEAKKVAPQNDSFGAQLPPMHQQQRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPTGAPTTTQTNGQGNYGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQCLPRPSTLGSAAKSNSAEDAASTKS", "length": 664, "header": "tr|A0A8C2LLP1-1|A0A8C2LLP1_CRIGR Computationally mapped isoform of Far upstream element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Fubp1 PE=4 SV=1 CANONICAL=A0A9J7J648-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LPE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648/entry#A0A8C2LPE1-1", "sequence": { "sequence": "MADYSTVPPPSSGSAGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDQPEAKKVAPQNDSFGAQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPTGAPTTTQTNGQGNYGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGFANHARSHHHLY", "length": 653, "header": "tr|A0A8C2LPE1-1|A0A9J7J648_CRIGR Computationally mapped isoform of Far upstream element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Fubp1 PE=4 SV=1 CANONICAL=A0A9J7J648-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F4M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648/entry#A0A9J7F4M3-1", "sequence": { "sequence": "MADYSTVPPPSSGSAGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDQPEAKKVAPQNDSFGAQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPTGAPTTTQTNGQGNYGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQCLPRPSTLGSAAKSNSAEDAASTKS", "length": 665, "header": "tr|A0A9J7F4M3-1|A0A9J7J648_CRIGR Computationally mapped isoform of Far upstream element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Fubp1 PE=4 SV=1 CANONICAL=A0A9J7J648-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F4M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648/entry#A0A9J7F4M5-1", "sequence": { "sequence": "MADYSTVPPPSSGSAGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDQPEAKKVAPQNDSFGAQLPPMHQQQRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPTGAPTTTQTNGQGNYGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGFANHARSHHHLY", "length": 652, "header": "tr|A0A9J7F4M5-1|A0A9J7J648_CRIGR Computationally mapped isoform of Far upstream element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Fubp1 PE=4 SV=1 CANONICAL=A0A9J7J648-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F5F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648/entry#A0A9J7F5F5-1", "sequence": { "sequence": "MADYSTVPPPSSGSAGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDGSWTNPSSTAHWEGMPSPFKDQPEAKKVAPQNDSFGAQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPTGAPTTTQTNGQGNYGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGFANHARSHHHLY", "length": 674, "header": "tr|A0A9J7F5F5-1|A0A9J7J648_CRIGR Computationally mapped isoform of Far upstream element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Fubp1 PE=4 SV=1 CANONICAL=A0A9J7J648-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F706-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648/entry#A0A9J7F706-1", "sequence": { "sequence": "MADYSTVPPPSSGSAGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDQPEAKKVAPQNDSFGAQLPPMHQQQRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPTGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQCLPRPSTLGSAAKSNSAEDAASTKS", "length": 661, "header": "tr|A0A9J7F706-1|A0A9J7J648_CRIGR Computationally mapped isoform of Far upstream element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Fubp1 PE=4 SV=1 CANONICAL=A0A9J7J648-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F8R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648/entry#A0A9J7F8R8-1", "sequence": { "sequence": "MADYSTVPPPSSGSAGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDGSWTNPSSTAHWEGMPSPFKDQPEAKKVAPQNDSFGAQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPTGAPTTTQTNGQGNYGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQV", "length": 662, "header": "tr|A0A9J7F8R8-1|A0A9J7J648_CRIGR Computationally mapped isoform of Far upstream element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Fubp1 PE=4 SV=1 CANONICAL=A0A9J7J648-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F8Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648/entry#A0A9J7F8Y0-1", "sequence": { "sequence": "MADYSTVPPPSSGSAGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDQPEAKKVAPQNDSFGAQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPTGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQCLPRPSTLGSAAKSNSAEDAASTKS", "length": 662, "header": "tr|A0A9J7F8Y0-1|A0A9J7J648_CRIGR Computationally mapped isoform of Far upstream element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Fubp1 PE=4 SV=1 CANONICAL=A0A9J7J648-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F986-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648/entry#A0A9J7F986-1", "sequence": { "sequence": "MADYSTVPPPSSGSAGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDGSWTNPSSTAHWEGMPSPFKDQPEAKKVAPQNDSFGAQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPTGAPTTTQTNGQGNYGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQCRFDPASIELAL", "length": 673, "header": "tr|A0A9J7F986-1|A0A9J7J648_CRIGR Computationally mapped isoform of Far upstream element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Fubp1 PE=4 SV=1 CANONICAL=A0A9J7J648-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J648-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648/entry#A0A9J7J648-1", "sequence": { "sequence": "MADYSTVPPPSSGSAGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDGSWTNPSSTAHWEGMPSPFKDQPEAKKVAPQNDSFGAQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPTGAPTTTQTNGQGNYGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQCLPRPSTLGSAAKSNSAEDAASTKS", "length": 686, "header": "tr|A0A9J7J648-1|A0A9J7J648_CRIGR Isoform 1 of Far upstream element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Fubp1 PE=4 SV=1 CANONICAL=A0A9J7J648-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J953-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648/entry#A0A9J7J953-1", "sequence": { "sequence": "MADYSTVPPPSSGSAGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDQPEAKKVAPQNDSFGAQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPTGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGFANHARSHHHLY", "length": 650, "header": "tr|A0A9J7J953-1|A0A9J7J953_CRIGR Computationally mapped isoform of Far upstream element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Fubp1 PE=4 SV=1 CANONICAL=A0A9J7J648-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JB53-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648/entry#A0A9J7JB53-1", "sequence": { "sequence": "MADYSTVPPPSSGSAGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDGSWTNPSSTAHWEGMPSPFKDQPEAKKVAPQNDSFGAQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPTGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQCLPRPSTLGSAAKSNSAEDAASTKS", "length": 683, "header": "tr|A0A9J7JB53-1|A0A9J7JB53_CRIGR Computationally mapped isoform of Far upstream element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Fubp1 PE=4 SV=1 CANONICAL=A0A9J7J648-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JB61-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648/entry#A0A9J7JB61-1", "sequence": { "sequence": "MADYSTVPPPSSGSAGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDGSWTNPSSTAHWEGMPSPFKDQPEAKKVAPQNDSFGAQLPPMHQQQRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPTGAPTTTQTNGQGNYGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQCLPRPSTLGSAAKSNSAEDAASTKS", "length": 685, "header": "tr|A0A9J7JB61-1|A0A9J7JB61_CRIGR Computationally mapped isoform of Far upstream element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Fubp1 PE=4 SV=1 CANONICAL=A0A9J7J648-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JCM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648/entry#A0A9J7JCM6-1", "sequence": { "sequence": "MADYSTVPPPSSGSAGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDGSWTNPSSTAHWEGMPSPFKDQPEAKKVAPQNDSFGAQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPTGAPTTTQTNGQGNYGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ", "length": 663, "header": "tr|A0A9J7JCM6-1|A0A9J7JCM6_CRIGR Computationally mapped isoform of Far upstream element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Fubp1 PE=4 SV=1 CANONICAL=A0A9J7J648-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KEA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648/entry#A0A9J7KEA9-1", "sequence": { "sequence": "MADYSTVPPPSSGSAGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDGSWTNPSSTAHWEGMPSPFKDQPEAKKVAPQNDSFGAQLPPMHQQQRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPTGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQCLPRPSTLGSAAKSNSAEDAASTKS", "length": 682, "header": "tr|A0A9J7KEA9-1|A0A9J7J648_CRIGR Computationally mapped isoform of Far upstream element-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Fubp1 PE=4 SV=1 CANONICAL=A0A9J7J648-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 573, "start_aa": "Thr", "end_pos": 573, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr573", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F4M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4M3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F4M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4M3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761415", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761415", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J648", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J648", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J648", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J648", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J648", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J648", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J648", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J648", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J648" }, { "id": "SM00322", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "K Homology", "eco_id": "ECO_0000259", "start_pos": 115, "end_pos": 185, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 573 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J7M0-1", "uniprot_ac": "A0A9J7J7M0", "uniprot_id": "A0A9J7J7M0_CRIGR", "mass": { "chemical_mass": 176972.0, "monoisotopic_mass": 176972.0 }, "refseq": { "ac": "XP_027248751", "name": "transmembrane protein 131-like isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248751" }, "gene_names": [ { "name": "Tmem131l", "type": "recommended", "evidence": [ { "id": "A0A9J7J7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7M0" } ] }, { "name": "Tmem131l", "type": "synonym", "evidence": [ { "id": "XP_027248751", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248751" } ] } ], "protein_names": [ { "name": "Transmembrane protein 131-like", "type": "recommended", "evidence": [ { "id": "A0A9J7J7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7M0/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 131-like isoform X4", "type": "synonym", "evidence": [ { "id": "XP_027248751", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248751" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027248751", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248751" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7M0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7M0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem131l", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7M0", "locus": {} } ], "crossref": [ { "id": "100771764", "url": "https://www.ncbi.nlm.nih.gov/gene/100771764", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771764", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771764", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7J7M0", "url": "https://www.orthodb.org/?gene=A0A9J7J7M0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22050", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22050", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22050:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22050:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12371", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12371", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19532", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19532", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24498", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24498", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027248751", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248751", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7F597", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F597", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F597-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F597-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J4U6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4U6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J4U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4U6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7M0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7M0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J9M8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J9M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9M8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGLRRPQSGAYRRTAAAVNLLLGVFQVLLSCCRPGGAQGQAIEPMPNVVELWQAEEGELLLPTQGDSEEDMEEPSQEQSFSEKLFIGKGLHFQPSVLDFGIQFLGHPAAKLLYVYNPSRDSEVVVNSMFTAAGHFHVPPVHCRVIPAMGRTSFRIIFLPTEEGTIESSLFINTSTHGVLSYHVSGVGTRRVSTEGSAEQLPNTYFLLPQVQSIQLSQTQEETTNTTLLRVQLECSLHNKVCQQLKSCYLGPGDALPLEMSIVVAVENSSRQPEENTQALLDHLSIVYVATAESDTTDESAVNMYVLHSGNNLIWIQDIHHFSQKNALPLQFEPVLLHTSTTNFTKIASFVCKAGTSCGSGIVDVRKRKHTPALRACLSSPVAQGYFRVDASTAQFHIESHKNTTGEWSIWYRSHFDHSIVLKDVFVSKEAKHILKVLSFPGPLFLPPGCWHIFSLKLAVKGIVLNLLTNVYLTTNTGAVFAIPLQIFSAPTKEGSLGFEVIAHCGMHYFMGKSKPETPTWDGSLSLDRSTWHVDSELANELYERWKKYKNGNVCRRNVLGMTQFASAKKSKESEPFVSFLPRLVLEPGLLLNFSATALRNSVVKYFVVRNPSPRPVSLQLLPLSLYPKPEAAVRLLHKWFGTDMQTINFTTGEFQLTKACPYQGEPSEESSFGMLHLYLQPLEMRRVGVVFTPVDYGKVTSLILIRNNLTVIDMVGVEGFGAQELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENVGPLPVTVTSLKINGYNCQGYGFQVLDCHPFSLNPNTSRDISIVFTPDFTSSWVIRELMLVTAADLEFHFTLNVTLPHHMLPVCAEVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKTRQRQSGSLSSQQNGGPVDVLSSHSHKNNCKNFLDTYSPSDKSRGKSCLPVGPPLSRIQNAAKRSPATYGHSQKKHKCSFYYSKQKASASMASSANIATEEKQTLTLASSLSAVKEDACTDVMSENWVSLKYASGVNVNLQKNLTLPKNVLNKEENSLKNTLVNNTSSECTVKEGIQTCMFPKETDIKTSENVVELKEQEEPCPQKTSKKPPETPLPKSPPQYQQSDMPEVSRKHGNNQQVPIKNEADSCETVKGVDTKLSSIKKSQRASPESTCSEKQDTPSVEQDDSYRKRKLQEKREGSTQSLNWNKNRTCRKNKKRGAAQASRPSEQNELKLVCSDFERPEPSNDIRSWCAQDSTGEMCKAGVEISGSSPARREEDSYYQKSEKKCADKFCSDSSSDCGSSSGSVRASRGSWGSWSSSSSDCDRKLVVDAQHLLPPGDGVSSQDFSPEASILVNLSKHMCSPTDVSSLSQFTESSSPSLPAAPSGAGEEKGLYPPGGLWPSQPVCLTSSFNCPAENSAPGVSQGPASIPDSSFIDWSASCEGQFPSVYCPLELNDYNAFPEENMNYANGFPCPSKVQTDFIGHSAHSTWNTPASTPTTWEHAGFVNSPSYLTSTRSLSPMSGLFGSIWAPQSDVYENCCPVSPATEHSTHMENQVMCKEYYPGFNPFRAYMNLDIWTSTANRNANFPLSRDSSYCGNA", "length": 1604, "header": "tr|A0A9J7J7M0-1|A0A9J7J7M0_CRIGR Isoform 1 of Transmembrane protein 131-like OS=Cricetulus griseus OX=10029 GN=Tmem131l PE=3 SV=1 CANONICAL=A0A9J7J7M0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F597-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7M0/entry#A0A9J7F597-1", "sequence": { "sequence": "MAGLRRPQSGAYRRTAAAVNLLLGVFQVLLSCCRPGGAQGQAIEPMPNVVELWQAEEGELLLPTQGDSEEDMEEPSQEQSFSEKLFIGKGLHFQPSVLDFGIQFLGHPAAKLLYVYNPSRDSEVVVNSMFTAAGHFHVPPVHCRVIPAMGRTSFRIIFLPTEEGTIESSLFINTSTHGVLSYHVSGVGTRRVSTEGSAEQLPNTYFLLPQVQSIQLSQTQEETTNTTLLRVQLECSLHNKVCQQLKSCYLGPGDALPLEMSIVVAVENSSRQPEENTQALLDHLSIVYVATAESDTTDESAVNMYVLHSGNNLIWIQDIHHFSQKNALPLQFEPVLLHTSTTNFTKIASFVCKAGTSCGSGIVDVRKRKHTPALRACLSSPVAQGYFRVDASTAQFHIESHKNTTGEWSIWYRSHFDHSIVLKDVFVSKEAKHILKVLSFPGPLFLPPGCWHIFSLKLAVKGIVLNLLTNVYLTTNTGAVFAIPLQIFSAPTKEGSLGFEVIAHCGMHYFMGKSKPETPTWDGSLSLDRSTWHVDSELANELYERWKKYKNGNVCRRNVLGMTQFASAKKSKESEPFVSFLPRLVLEPGLLLNFSATALRNSVVKYFVVRNPSPRPVSLQLLPLSLYPKPEAAVRLLHKWFGTDMQTINFTTGEFQLTKACPYQGEPSEESSFGMLHLYLQPLEMRRVGVVFTPVDYGKVTSLILIRNNLTVIDMVGVEGFGAQELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENVGPLPVTVTSLKINGYNCQGYGFQVLDCHPFSLNPNTSRDISIVFTPDFTSSWVIRELMLVTAADLEFHFTLNVTLPHHMLPVCAEVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKTRQRQSGSLSSQQNGGPVDVLSSHSHKNNCKNFLDTYSPSDKSRGKSCLPVGPPLSRIQNAAKRSPATYGHSQKKHKCSFYYSKQKASASMASSANIATEEKQTLTLASSLSAVKEDACTDVMSENWVSLKYASGVNVNLQKNLTLPKNVLNKEENSLKNTLVNNTSSECTVKEGIQTCMFPKETDIKTSENVVELKEQEEPCPQKTSKKPPETPLPKSPPQYQQSDMPEVSRKHGNNQQVPIKNEADSCETVKGVDTKLSSIKKSQRASPESTCSEKQDTPSVEQDDSYRKRKLQEKREGSTQSLNWNKNRTCRKNKKRGAAQASRPSEQNELKLVCSDFERPEPSNDIRSWCAQDSTGEMCKAGVEISGSSPARREEDSYYQKSEKKCADKFCSDSSSDCGSSSGSVRASRGSWGSWSSSSSDCDRKLVVDAQHLLPPGDGVSSQDFSPEASILVNLSKHMCSPTDVSSLSQFTESSSPSLPAAPSGAGEEKGLYPPGGLWPSQPVCLTSSFNCPAENSAPGVSQGPASIPDSFIDWSASCEGQFPSVYCPLELNDYNAFPEENMNYANGFPCPSKVQTDFIGHSAHSTWNTPASTPTTWEHAGFVNSPSYLTSTRSLSPMSGLFGSIWAPQSDVYENCCPVSPATEHSTHMENQVMCKEYYPGFNPFRAYMNLDIWTSTANRNANFPLSRDSSYCGNA", "length": 1603, "header": "tr|A0A9J7F597-1|A0A9J7J7M0_CRIGR Computationally mapped isoform of Transmembrane protein 131-like OS=Cricetulus griseus OX=10029 GN=Tmem131l PE=3 SV=1 CANONICAL=A0A9J7J7M0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J4U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7M0/entry#A0A9J7J4U6-1", "sequence": { "sequence": "MAGLRRPQSGAYRRTAAAVNLLLGVFQVLLSCCRPGGAQGQAIEPMPNVVELWQAEEGELLLPTQGDSEEDMEEPSQEQSFSEKLFIGKGLHFQPSVLDFGIQFLGHPAAKLLYVYNPSRDSEVVVNSMFTAAGHFHVPPVHCRVIPAMGRTSFRIIFLPTEEGTIESSLFINTSTHGVLSYHVSGVGTRRVSTEGSAEQLPNTYFLLPQVQSIQLSQTQEETTNTTLLRVQLECSLHNKVCQQLKSCYLGPGDALPLEMSIVVAVENSSRQPEENTQALLDHLSIVYVATAESDTTDESAVNMYVLHSGNNLIWIQDIHHFSQKNALPLQFEPVLLHTSTTNFTKIASFVCKAGTSCGSGIVDVRKRKHTPALRACLSSPVAQGYFRVDASTAQFHIESHKNTTGEWSIWYRSHFDHSIVLKDVFVSKEAKHILKVLSFPGPLFLPPGCWHIFSLKLAVKGIVLNLLTNVYLTTNTGAVFAIPLQIFSAPTKEGSLGFEVIAHCGMHYFMGKSKPETPTWDGSLSLDRSTWHVDSELANELYERWKKYKNGNVCRRNVLGMTQFASAKKSKESEPFVSFLPRLVLEPGLLLNFSATALRNSVVKYFVVRNPSPRPVSLQLLPLSLYPKPEAAVRLLHKWFGTDMQTINFTTGEFQLTKACPYQGEPSEESSFGMLHLYLQPLEMRRVGVVFTPVDYGKVTSLILIRNNLTVIDMVGVEGFGAQELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENVGPLPVTVTSLKINGYNCQGYGFQVLDCHPFSLNPNTSRDISIVFTPDFTSSWVIRELMLVTAADLEFHFTLNVTLPHHMLPVCAEVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKTRQRQSGSLSSQQNGGPVDVLSSHSHKNNCKNFLDTYSPSDKSRGKSCLPVGPPLSRIQNAAKRSPATYGHSQKKHKCSFYYSKQKASASMASSANIATEEKQTLTLASSLSAVKEDACTDVMSENWVSLKYASGVNVNLQKNLTLPKNVLNKEENSLKNTLVNNTSSECTVKEGIQTCMFPKETDIKTSENVVELKEQEEPCPQKTSKKPPETPLPKSPPQYQQSDMPEVSRKHGNNQQVPIKNEADSCETVKGVDTKLSSIKKSQRASPESTCSEKQDTPSVEDDSYRKRKLQEKREGSTQSLNWNKNRTCRKNKKRGAAQASRPSEQNELKLVCSDFERPEPSNDIRSWCAQDSTGEMCKAGVEISGSSPARREEDSYYQKSEKKCADKFCSDSSSDCGSSSGSVRASRGSWGSWSSSSSDCDRKLVVDAQHLLPPGDGVSSQDFSPEASILVNLSKHMCSPTDVSSLSQFTESSSPSLPAAPSGAGEEKGLYPPGGLWPSQPVCLTSSFNCPAENSAPGVSQGPASIPDSSFIDWSASCEGQFPSVYCPLELNDYNAFPEENMNYANGFPCPSKVQTDFIGHSAHSTWNTPASTPTTWEHAGFVNSPSYLTSTRSLSPMSGLFGSIWAPQSDVYENCCPVSPATEHSTHMENQVMCKEYYPGFNPFRAYMNLDIWTSTANRNANFPLSRDSSYCGNA", "length": 1603, "header": "tr|A0A9J7J4U6-1|A0A9J7J4U6_CRIGR Computationally mapped isoform of Transmembrane protein 131-like OS=Cricetulus griseus OX=10029 GN=Tmem131l PE=3 SV=1 CANONICAL=A0A9J7J7M0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J7M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7M0/entry#A0A9J7J7M0-1", "sequence": { "sequence": "MAGLRRPQSGAYRRTAAAVNLLLGVFQVLLSCCRPGGAQGQAIEPMPNVVELWQAEEGELLLPTQGDSEEDMEEPSQEQSFSEKLFIGKGLHFQPSVLDFGIQFLGHPAAKLLYVYNPSRDSEVVVNSMFTAAGHFHVPPVHCRVIPAMGRTSFRIIFLPTEEGTIESSLFINTSTHGVLSYHVSGVGTRRVSTEGSAEQLPNTYFLLPQVQSIQLSQTQEETTNTTLLRVQLECSLHNKVCQQLKSCYLGPGDALPLEMSIVVAVENSSRQPEENTQALLDHLSIVYVATAESDTTDESAVNMYVLHSGNNLIWIQDIHHFSQKNALPLQFEPVLLHTSTTNFTKIASFVCKAGTSCGSGIVDVRKRKHTPALRACLSSPVAQGYFRVDASTAQFHIESHKNTTGEWSIWYRSHFDHSIVLKDVFVSKEAKHILKVLSFPGPLFLPPGCWHIFSLKLAVKGIVLNLLTNVYLTTNTGAVFAIPLQIFSAPTKEGSLGFEVIAHCGMHYFMGKSKPETPTWDGSLSLDRSTWHVDSELANELYERWKKYKNGNVCRRNVLGMTQFASAKKSKESEPFVSFLPRLVLEPGLLLNFSATALRNSVVKYFVVRNPSPRPVSLQLLPLSLYPKPEAAVRLLHKWFGTDMQTINFTTGEFQLTKACPYQGEPSEESSFGMLHLYLQPLEMRRVGVVFTPVDYGKVTSLILIRNNLTVIDMVGVEGFGAQELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENVGPLPVTVTSLKINGYNCQGYGFQVLDCHPFSLNPNTSRDISIVFTPDFTSSWVIRELMLVTAADLEFHFTLNVTLPHHMLPVCAEVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKTRQRQSGSLSSQQNGGPVDVLSSHSHKNNCKNFLDTYSPSDKSRGKSCLPVGPPLSRIQNAAKRSPATYGHSQKKHKCSFYYSKQKASASMASSANIATEEKQTLTLASSLSAVKEDACTDVMSENWVSLKYASGVNVNLQKNLTLPKNVLNKEENSLKNTLVNNTSSECTVKEGIQTCMFPKETDIKTSENVVELKEQEEPCPQKTSKKPPETPLPKSPPQYQQSDMPEVSRKHGNNQQVPIKNEADSCETVKGVDTKLSSIKKSQRASPESTCSEKQDTPSVEQDDSYRKRKLQEKREGSTQSLNWNKNRTCRKNKKRGAAQASRPSEQNELKLVCSDFERPEPSNDIRSWCAQDSTGEMCKAGVEISGSSPARREEDSYYQKSEKKCADKFCSDSSSDCGSSSGSVRASRGSWGSWSSSSSDCDRKLVVDAQHLLPPGDGVSSQDFSPEASILVNLSKHMCSPTDVSSLSQFTESSSPSLPAAPSGAGEEKGLYPPGGLWPSQPVCLTSSFNCPAENSAPGVSQGPASIPDSSFIDWSASCEGQFPSVYCPLELNDYNAFPEENMNYANGFPCPSKVQTDFIGHSAHSTWNTPASTPTTWEHAGFVNSPSYLTSTRSLSPMSGLFGSIWAPQSDVYENCCPVSPATEHSTHMENQVMCKEYYPGFNPFRAYMNLDIWTSTANRNANFPLSRDSSYCGNA", "length": 1604, "header": "tr|A0A9J7J7M0-1|A0A9J7J7M0_CRIGR Isoform 1 of Transmembrane protein 131-like OS=Cricetulus griseus OX=10029 GN=Tmem131l PE=3 SV=1 CANONICAL=A0A9J7J7M0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J9M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7M0/entry#A0A9J7J9M8-1", "sequence": { "sequence": "MAGLRRPQSGAYRRTAAAVNLLLGVFQVLLSCCRPGGAQGQAIEPMPNVVELWQAEEGELLLPTQGDSEEDMEEPSQEQSFSEKLFIGKGLHFQPSVLDFGIQFLGHPAAKLLYVYNPSRDSEVVVNSMFTAAGHFHVPPVHCRVIPAMGRTSFRIIFLPTEEGTIESSLFINTSTHGVLSYHEETTNTTLLRVQLECSLHNKVCQQLKSCYLGPGDALPLEMSIVVAVENSSRQPEENTQALLDHLSIVYVATAESDTTDESAVNMYVLHSGNNLIWIQDIHHFSQKNALPLQFEPVLLHTSTTNFTKIASFVCKAGTSCGSGIVDVRKRKHTPALRACLSSPVAQGYFRVDASTAQFHIESHKNTTGEWSIWYRSHFDHSIVLKDVFVSKEAKHILKVLSFPGPLFLPPGCWHIFSLKLAVKGIVLNLLTNVYLTTNTGAVFAIPLQIFSAPTKEGSLGFEVIAHCGMHYFMGKSKPETPTWDGSLSLDRSTWHVDSELANELYERWKKYKNGNVCRRNVLGMTQFASAKKSKESEPFVSFLPRLVLEPGLLLNFSATALRNSVVKYFVVRNPSPRPVSLQLLPLSLYPKPEAAVRLLHKWFGTDMQTINFTTGEFQLTKACPYQGEPSEESSFGMLHLYLQPLEMRRVGVVFTPVDYGKVTSLILIRNNLTVIDMVGVEGFGAQELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENVGPLPVTVTSLKINGYNCQGYGFQVLDCHPFSLNPNTSRDISIVFTPDFTSSWVIRELMLVTAADLEFHFTLNVTLPHHMLPVCAEVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKTRQRQSGSLSSQQNGGPVDVLSSHSHKNNCKNFLDTYSPSDKSRGKSCLPVGPPLSRIQNAAKRSPATYGHSQKKHKCSFYYSKQKASASMASSANIATEEKQTLTLASSLSAVKEDACTDVMSENWVSLKYASGVNVNLQKNLTLPKNVLNKEENSLKNTLVNNTSSECTVKEGIQTCMFPKETDIKTSENVVELKEQEEPCPQKTSKKPPETPLPKSPPQYQQSDMPEVSRKHGNNQQVPIKNEADSCETVKGVDTKLSSIKKSQRASPESTCSEKQDTPSVEQDDSYRKRKLQEKREGSTQSLNWNKNRTCRKNKKRGAAQASRPSEQNELKLVCSDFERPEPSNDIRSWCAQDSTGEMCKAGVEISGSSPARREEDSYYQKSEKKCADKFCSDSSSDCGSSSGSVRASRGSWGSWSSSSSDCDRKLVVDAQHLLPPGDGVSSQDFSPEASILVNLSKHMCSPTDVSSLSQFTESSSPSLPAAPSGAGEEKGLYPPGGLWPSQPVCLTSSFNCPAENSAPGVSQGPASIPDSSFIDWSASCEGQFPSVYCPLELNDYNAFPEENMNYANGFPCPSKVQTDFIGHSAHSTWNTPASTPTTWEHAGFVNSPSYLTSTRSLSPMSGLFGSIWAPQSDVYENCCPVSPATEHSTHMENQVMCKEYYPGFNPFRAYMNLDIWTSTANRNANFPLSRDSSYCGNA", "length": 1567, "header": "tr|A0A9J7J9M8-1|A0A9J7J9M8_CRIGR Computationally mapped isoform of Transmembrane protein 131-like OS=Cricetulus griseus OX=10029 GN=Tmem131l PE=3 SV=1 CANONICAL=A0A9J7J7M0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F597", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F597" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F597", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F597" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771764", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771764", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7M0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7M0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5Q3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774778", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774778", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE07", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE07" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE07", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE07" } ], "pmid": "" }, { "name": "poly(A) binding", "id": "GO:0008143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008143", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE07", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE07" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE07", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE07" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE07", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE07" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE07", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE07" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE07", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE07" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HE07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE07" }, { "id": "SM00322", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "K Homology", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 156, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J8F2-1", "uniprot_ac": "A0A9J7J8F2", "uniprot_id": "A0A9J7J8F2_CRIGR", "mass": { "chemical_mass": 204338.0, "monoisotopic_mass": 204338.0 }, "refseq": { "ac": "XP_003498842", "name": "probable ATP-dependent RNA helicase DDX60 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498842" }, "gene_names": [ { "name": "Ddx60", "type": "recommended", "evidence": [ { "id": "A0A9J7J8F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8F2" } ] }, { "name": "Ddx60", "type": "synonym", "evidence": [ { "id": "XP_003498842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498842" } ] } ], "protein_names": [ { "name": "Probable ATP-dependent RNA helicase DDX60 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7J8F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8F2/entry#names_and_taxonomy" } ] }, { "name": "probable ATP-dependent RNA helicase DDX60 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003498842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498842" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613703.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003498842.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003498842", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498842" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8F2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ddx60", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8F2", "locus": {} } ], "crossref": [ { "id": "cd18025", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18025", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760761", "url": "https://www.ncbi.nlm.nih.gov/gene/100760761", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760761", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760761", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDNRINE", "url": "https://omabrowser.org/oma/group/QDNRINE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J8F2", "url": "https://www.orthodb.org/?gene=A0A9J7J8F2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44533", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44533", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44533:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44533:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26167", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26167", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003498842", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498842", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7F6M6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F6M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6M6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HB68", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HB68-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HB68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8F2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8F2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASRMEKHPTVVLEELMSQLILEKMPKADYSSLFNDFVESEFFLIDGDSLFVTCLFEKSLKPGQSLHFFYLVERYLLDIISKGGQFAIVFFKDAEYAYFNVPALLTLRTALILHLQKNTTIDVQTKFSGCLSKDWSIFLNQSCPYFLILADEGLNNQQTHLFNFVVIQSWAEKINIVLFSGQTSDILRLYAYFMHSSYSEQKFYKENMNEIMIAYKGLIQHLEKHRDEHLTTLFGDLKFNNVMEKACETISRLTQLWPEGSDIRRVLCVTSCSLSLEMYHCFLENGEEKASKQTCEVKQEKGNCLTLKDVEDFCKLHCLSVVFQLHLPLSQRAQSRFITSGWIQDLKTVFKMKKWCEYFILSNLHTFELWSLNSLHLSDLSDEPLLKNIAFYYENENAQGLDLNVGDVIMKEYVHLWDTVSKLVRKFDVGKPFPVRTTKCHFLKKTPSPIKEISQEKMPNLGFIPMSCSLVDEFTGDILKDLPFLKSDDPIVTSLVKHKEFDELVHWHSHRPLSDDYDRTKASFDEHSRDPRQLRSLQKYQVFQRFYGNSLESVSSKIITTQSVKPKKDCSKSRSTKAHETKADIIARENKKRLIAKEEQKEEQKWNVLSSSIEKEMKRNLNSGMQKLEEFLKSCKSNSVKVQAEKVGLTACLTAWREHCRAEGETTKNLNIAIDMMKRIHSLLDKHSELLQEGDRKLIARCLKYLGFDELANSLYPTQDAVDDLKKTKKNKYSLGIGPARFQLQYMGHHLIREERKDPDPRVQDFIPDTWQRELLDVVDNYESAVIVAPTSSGKTYASYYCMEKVLKESNEGVVVYVAPTKALVNQVAATVQSRYTKILPTGGALCGVFTRDYRHDALNCQVLVTVPACFEILLLAPHRQSWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKRYWKKVDSEMGKLTFTKRNAGSRGSHHKDQVQARQSYKVRLVLYGERYNDLEKYLCSVRQDDVCFDHFHPCAALTTDHIEKYGFPSDLAFSPRESIQLYDTMLQVWKSWPQAQNLCPENFTHLKNKIVIKKSDAREYEKSLKEEFTNWVKNGNEEQARMVLQKLSPNFCDYSGQMLKFFPNLVEKLREMEKLPALFFLFRFASVEQCAEDACQFLEDKQDEKRPPNADKEAHVMAKKLRKVKKSLEKPQQIIYRLSSVEGGAEAACQFLEVQQEEKRPPNSDKEAHAMANKLQKVKKSLEKPQNIRDEKSKKPSRRLDQIIMHEAEYNYLLKSLEKHLEIPEDCTYADQKAIDDESLQMVFDRVKFQRKGNTLKKLARRGIGYHHSSMSFKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFVQNSVYLDALNFRQMSGRAGRRGQDLLGDVYFFNIPLPKISKLIKSKVPELRGQFPLSISLILRLLLLASKADDLEDGKAKALSVLKHSLLSFKHPRVIDMLKLYFLYSLQFLVKEGHIDQEGNPTGFAGLVTHLHYHEPSNLVFVNFLVRGLFHNLCQPTHKGSKCFSKDVMEKLVLVLANLFGRRYLPAKFQDVNIKFYQSKVFLDDLPEDFNEALNEYNMKVTMDFAAFLLIVSRLADMKQEYQLPLSKIEFAGKECEDSPLVSHLMSCREGRVAVSPFVCLSGNFDEDLLHPGVSDNVVLHTIAVNHCQAPVLWPHRFDNTGRKMPLNAYALDFYKHGSLVGLVQDNGIHQGEAYHLLKDFFLTIKSISVSLRELCENEEDNVVLAFEQLVESFKEKFEKV", "length": 1771, "header": "tr|A0A9J7J8F2-1|A0A9J7J8F2_CRIGR Isoform 1 of Probable ATP-dependent RNA helicase DDX60 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ddx60 PE=3 SV=1 CANONICAL=A0A9J7J8F2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F6M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8F2/entry#A0A9J7F6M6-1", "sequence": { "sequence": "MASRMEKHPTVVLEELMSQLILEKMPKADYSSLFNDFVESEFFLIDGDSLFVTCLFEKSLKPGQSLHFFYLVERYLLDIISKGGQFAIVFFKDAEYAYFNVPALLTLRTALILHLQKNTTIDVQTKFSGCLSKDWSIFLNQSCPYFLILADEGLNNQQTHLFNFVVIQSWAEKINIVLFSGQTSDILRLYAYFMHSSYSEQKFYKENMNEIMIAYKGLIQHLEKHRDEHLTTLFGDLKFNNVMEKACETISRLTQLWPEGSDIRRVLCVTSCSLSLEMYHCFLENGEEKASKQTCEVKQEKGNCLTLKDVEDFCKLHCLSVVFQLHLPLSQRAQSRFITSGWIQDLKTVFKMKKWCEYFILSNLHTFELWSLNSLHLSDLSDEPLLKNIAFYYENENAQGLDLNVGDVIMKEYVHLWDTVSKLVRKFDVGKPFPVRTTKCHFLKKTPSPIKEISQEKMPNLGFIPMSCSLVDEFTGDILKDLPFLKSDDPIVTSLVKHKEFDELVHWHSHRPLSDDYDRTKASFDEHSRDPRQLRSLQKYQVFQRFYGNSLESVSSKIITTQSVKPKKDCSKSRSTKAHETKADIIARENKKRLIAKEEQKEEQKWNVLSSSIEKEMKRNLNSGMQKLEEFLKSCKSNSVKVQAEKVGLTACLTAWREHCRAEGETTKNLNIAIDMMKRIHSLLDKHSELLQEGDRKLIARCLKYLGFDELANSLYPTQDAVDDLKKTKKNKYSLGIGPARFQLQYMGHHLIREERKDPDPRVQDFIPDTWQRELLDVVDNYESAVIVAPTSSGKTYASYYCMEKVLKESNEGVVVYVAPTKALVNQVAATVQSRYTKILPTGGALCGVFTRDYRHDALNCQVLVTVPACFEILLLAPHRQSWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKRYWKKVDSEMGKLTFTKRNAGSRGSHHKDQVQARQSYKVRLVLYGERYNDLEKYLCSVRQDDVCFDHFHPCAALTTDHIEKYGFPSDLAFSPRESIQLYDTMLQVWKSWPQAQNLCPENFTHLKNKIVIKKSDAREYEKSLKEEFTNWVKNGNEEQARMVLQKLSPNFCDYSGQMLKFFPNLVEKLREMEKLPALFFLFRFASVEQCAEDACQFLEDKQDEKRPPNADKEAHVMAKKLRKVKKSLEKPQQIIYRLSSVEGGAEAACQFLEVQQEEKRPPNSDKEAHAMANKLQKVKKSLEKPQNIRDEKSKKPSRRLDQIIMHEAEYNYLLKSLEKHLEIPEDCTYADQKAIDDESLQMVFDRVKFQRKGNTLKKLARRGIGYHHSSMSFKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFVQNSVYLDALNFRQMSGRAGRRGQDLLGDVYFFNIPLPKISKLIKSKVPELRGQFPLSISLILRLLLLASKADDLEDGKAKALSVLKHSLLSFKHPRVIDMLKLYFLYSLQFLVKEGHIDQEGNPTGFAGLVTHLHYHEPSNLVFVNFLVRGLFHNLCQPTHKGSKCFSKDVMEKLVLVLANLFGRRYLPAKFQDVNIKFYQSKVFLDDLPEDFNEALNEYNMKVTMDFAAFLLIVSRLADMKQEYQLPLSKIEFAGKECEDSPLVSHLMSCREGRVAVSPFVCLSGNFDEDLLHPGVSDNCLLA", "length": 1671, "header": "tr|A0A9J7F6M6-1|A0A9J7J8F2_CRIGR Computationally mapped isoform of Probable ATP-dependent RNA helicase DDX60 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ddx60 PE=3 SV=1 CANONICAL=A0A9J7J8F2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HB68-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8F2/entry#A0A9J7HB68-1", "sequence": { "sequence": "MASRMEKHPTVVLEELMSQLILEKMPKADYSSLFNDFVESEFFLIDGDSLFVTCLFEKSLKPGQSLHFFYLVERYLLDIISKGGQFAIVFFKDAEYAYFNVPALLTLRTALILHLQKNTTIDVQTKFSGCLSKDWSIFLNQSCPYFLILADEGLNNQQTHLFNFVVIQSWAEKINIVLFSGQTSDILRLYAYFMHSSYSEQKFYKENMNEIMIAYKGLIQHLEKHRDEHLTTLFGDLKFNNVMEKACETISRLTQLWPEGSDIRRVLCVTSCSLSLEMYHCFLENGEEKASKQTCEVKQEKGNCLTLKDVEDFCKLHCLSVVFQLHLPLSQRAQSRFITSGWIQDLKTVFKMKKWCEYFILSNLHTFELWSLNSLHLSDLSDEPLLKNIAFYYENENAQGLDLNVGDVIMKEYVHLWDTVSKLVRKFDVGKPFPVRTTKCHFLKKTPSPIKEISQEKMPNLGFIPMSCSLVDEFTGDILKDLPFLKSDDPIVTSLVKHKEFDELVHWHSHRPLSDDYDRTKASFDEHSRDPRQLRSLQKYQVFQRFYGNSLESVSSKIITTQSVKPKKDCSKSRSTKAHETKADIIARENKKRLIAKEEQKEEQKWNVLSSSIEKEMKRNLNSGMQKLEEFLKSCKSNSVKVQAEKVGLTACLTAWREHCRAEGETTKNLNIAIDMMKRIHSLLDKHSELLQEGDRKLIARCLKYLGFDELANSLYPTQDAVDDLKKTKKNKYSLGIGPARFQLQYMGHHLIREERKDPDPRVQDFIPDTWQRELLDVVDNYESAVIVAPTSSGKTYASYYCMEKVLKESNEGVVVYVAPTKALVNQVAATVQSRYTKILPTGGALCGVFTRDYRHDALNCQVLVTVPACFEILLLAPHRQSWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKRYWKKVDSEMGKLTFTKRNAGSRGSHHKDQVQARQSYKVRLVLYGERYNDLEKYLCSVRQDDVCFDHFHPCAALTTDHIEKYGFPSDLAFSPRESIQLYDTMLQVWKSWPQAQNLCPENFTHLKNKIVIKKSDAREYEKSLKEEFTNWVKNGNEEQARMVLQKLSPNFCDYSGQMLKFFPNLVEKLREMEKLPALFFLFRFASVEQCAEDACQFLEDKQDEKRPPNADKEAHVMAKKLRKVKKSLEKPQQIIYRLSSVEGGAEAACQFLEVQQEEKRPPNSDKEAHAMANKLQKVKKSLEKPQNIRDEKSKKPSRRLDQIIMHEAEYNYLLKSLEKHLEIPEDCTYADQKAIDDESLQMVFDRVKFQRKGNTLKKLARRGIGYHHSSMSFKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFVQNSVYLDALNFRQMSGRAGRRGQDLLGDVYFFNIPLPKISKLIKSKVPELRGQFPLSISLILRLLLLASKADDLEDGKAKALSVLKHSLLSFKHPRVIDMLKLYFLYSLQFLVKEGHIDQEGNPTGFAGLVTHLHYHEPSNLVFVNFLVRGLFHNLCQPTHKDPDVELSATSPVQHVPVYPSQ", "length": 1550, "header": "tr|A0A9J7HB68-1|A0A9J7J8F2_CRIGR Computationally mapped isoform of Probable ATP-dependent RNA helicase DDX60 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ddx60 PE=3 SV=1 CANONICAL=A0A9J7J8F2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J8F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8F2/entry#A0A9J7J8F2-1", "sequence": { "sequence": "MASRMEKHPTVVLEELMSQLILEKMPKADYSSLFNDFVESEFFLIDGDSLFVTCLFEKSLKPGQSLHFFYLVERYLLDIISKGGQFAIVFFKDAEYAYFNVPALLTLRTALILHLQKNTTIDVQTKFSGCLSKDWSIFLNQSCPYFLILADEGLNNQQTHLFNFVVIQSWAEKINIVLFSGQTSDILRLYAYFMHSSYSEQKFYKENMNEIMIAYKGLIQHLEKHRDEHLTTLFGDLKFNNVMEKACETISRLTQLWPEGSDIRRVLCVTSCSLSLEMYHCFLENGEEKASKQTCEVKQEKGNCLTLKDVEDFCKLHCLSVVFQLHLPLSQRAQSRFITSGWIQDLKTVFKMKKWCEYFILSNLHTFELWSLNSLHLSDLSDEPLLKNIAFYYENENAQGLDLNVGDVIMKEYVHLWDTVSKLVRKFDVGKPFPVRTTKCHFLKKTPSPIKEISQEKMPNLGFIPMSCSLVDEFTGDILKDLPFLKSDDPIVTSLVKHKEFDELVHWHSHRPLSDDYDRTKASFDEHSRDPRQLRSLQKYQVFQRFYGNSLESVSSKIITTQSVKPKKDCSKSRSTKAHETKADIIARENKKRLIAKEEQKEEQKWNVLSSSIEKEMKRNLNSGMQKLEEFLKSCKSNSVKVQAEKVGLTACLTAWREHCRAEGETTKNLNIAIDMMKRIHSLLDKHSELLQEGDRKLIARCLKYLGFDELANSLYPTQDAVDDLKKTKKNKYSLGIGPARFQLQYMGHHLIREERKDPDPRVQDFIPDTWQRELLDVVDNYESAVIVAPTSSGKTYASYYCMEKVLKESNEGVVVYVAPTKALVNQVAATVQSRYTKILPTGGALCGVFTRDYRHDALNCQVLVTVPACFEILLLAPHRQSWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKRYWKKVDSEMGKLTFTKRNAGSRGSHHKDQVQARQSYKVRLVLYGERYNDLEKYLCSVRQDDVCFDHFHPCAALTTDHIEKYGFPSDLAFSPRESIQLYDTMLQVWKSWPQAQNLCPENFTHLKNKIVIKKSDAREYEKSLKEEFTNWVKNGNEEQARMVLQKLSPNFCDYSGQMLKFFPNLVEKLREMEKLPALFFLFRFASVEQCAEDACQFLEDKQDEKRPPNADKEAHVMAKKLRKVKKSLEKPQQIIYRLSSVEGGAEAACQFLEVQQEEKRPPNSDKEAHAMANKLQKVKKSLEKPQNIRDEKSKKPSRRLDQIIMHEAEYNYLLKSLEKHLEIPEDCTYADQKAIDDESLQMVFDRVKFQRKGNTLKKLARRGIGYHHSSMSFKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFVQNSVYLDALNFRQMSGRAGRRGQDLLGDVYFFNIPLPKISKLIKSKVPELRGQFPLSISLILRLLLLASKADDLEDGKAKALSVLKHSLLSFKHPRVIDMLKLYFLYSLQFLVKEGHIDQEGNPTGFAGLVTHLHYHEPSNLVFVNFLVRGLFHNLCQPTHKGSKCFSKDVMEKLVLVLANLFGRRYLPAKFQDVNIKFYQSKVFLDDLPEDFNEALNEYNMKVTMDFAAFLLIVSRLADMKQEYQLPLSKIEFAGKECEDSPLVSHLMSCREGRVAVSPFVCLSGNFDEDLLHPGVSDNVVLHTIAVNHCQAPVLWPHRFDNTGRKMPLNAYALDFYKHGSLVGLVQDNGIHQGEAYHLLKDFFLTIKSISVSLRELCENEEDNVVLAFEQLVESFKEKFEKV", "length": 1771, "header": "tr|A0A9J7J8F2-1|A0A9J7J8F2_CRIGR Isoform 1 of Probable ATP-dependent RNA helicase DDX60 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ddx60 PE=3 SV=1 CANONICAL=A0A9J7J8F2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F6M6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6M6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F6M6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6M6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760761", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760761", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K744-1", "protein_name": "DEXD/H-box helicase 60", "gene_name": "LOC134478918", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKRCTMFLEGMSQLILENIPRADYSSLFNDFVESEFFLIDGDSLLLTCVCEMSLEPGQSLHFFYLVERYLLDVTSKGGQFAIVFFKDAEYAYFSVPELLTLRTSLILHLQKNTTIEVWTMFSNCLSEEWSICLNQSCPYFLIVADEGLDHLQTHLLNFVVIQAWAAKVNVVLFSGQTSDILRLYAYFMQSSYTNQMFFKKNEETIMNVYKALIEQLEKYRDRALTPLFGDLKFNDMEKEVSEIVSLLKQLWPEGSDIRRVFCVTSCSLFLEMYHSYLENREKRASTETSEVTQKPDNCLTLKDVEDFCKLHCLSVAFQLHLPLSQRARSRFITSNWIQDLQTVLKMKEWCEYFTLNNVDIFEFWSLDLLHVSDLSDEPLLKNIAFYYEYENKGGLDLKVGDVIMKEYIHLWDTVSKLVKKFDVGKPTPLRTTKVHFIEKTLSPIKESSQETMPNLGFIPISCNLVDEFTRDILKDLPFLKSDDPIVTSLVKHKEFDELVHWHSHRPLSDDYDRTKATFDDKKDPYYLSRLQKYHRFQRLYGSSLESVTSKMITTEGPKPKKDCIKSKRTKAHKTKAEIIVRENKKRLIAEEEQKEGQKWSALSFSIEEEMRRNLNSGIKKLEEFLKSCKSSSVKTQAERVGLQACLKAWKEHCRAEGKTTKDFNIAVNMMKRIHSLLEKQSEFLQEADQKLIARCLTYLGFYELADSLCPTQDTADDVKMTKKKYSVGIGPARFQLQYMGHYLIREERKDPDPRVQDFIPDTWQRELLDVVDNYESAVIVAPTSSGKTYASYYCMEKVLKESNEGVVVYVAPTKALVNQVAATVQNRYTKNMPGGEALCGVFTRDYRHEALNSQVLITVPACFEILLLAPHRQNWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPQHLTEWLQSVKRYWKQVDSTMEQGSVSQRNAATRGSYHKDRVQARQSYKVRLVLYGERYNDLEKYLCSVRQGDVCFDHFHPCAALTTDHIEKYGFPSDLALSPRESIQLYDTMCQVWKSWPQAQNLCPENFTQFKNKIVIKKLDARKYEESLKEEFTNWVKNGNEKEAQLVLKKLSPDYHDYSGQMLDFFPCLVEKLRKMEKLPALFFLFSLDTVEECAENVCEFLEEKQEEKRPPKADKEAYIMANKLRKVKKSLEKQKIDEKGQKSSRRLDQSIMYEAEHNYLLKSLEKNLEIPKDCTYADQKAIDEETLQIVFGRVKCGKKGDTLKKLARRGIGYHHRSMTAKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFAQNSVYLDALNYRQMSGRAGRRGQDLLGDVYFFDIPLPKIGKLIKSKVPELRGQFPLSITLILRLMLLATKADDLEDGKAKALSVLKHSLLSFKQPRATDMLKLYFLYSLQFLVKEGHIDQEGNPTGFAGLVTHLNYHEPSNLVFVSFLVKGLFHKLCQPTSKDSKCFSEDVMEKLVLVLANLFGRIYIPAKFYEVNTKFYQSKVFLDDLPQDFSDALLAYNMQVTRDFASFLLIVSRLADMKQEYQLPLSKIEFAGKECEDSPLVSHLMSCKEGRMAVSPFVCLSGNFDVDLLSPGVPNHVTLHTICINHAQAPVLWPHRLDSQGRKMPLNAYALDFYKHGSLTGLVQDNGIHPGDAYNLLKDFYLTIKSISVSLRELCENEEDNVVLAFEQLSKSFHEKFELV", "length": 1708 }, "evidence": [ { "id": "A0A9J7J8F2", "url": "https://omabrowser.org/oma/group/A0A9J7J8F2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A5G2QRV7-1", "protein_name": "DExD/H-box helicase 60", "gene_name": "DDX60", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDLEKYMMFLEDMSQLILNEVPKADYDSLFNDFVESEFFLLDGDSLLIMCVCEKSLKQGQDLHFFYLVERYLVDLITKGGQFAVVFFKDAENTYFNLPELLPLRTALILHLQHNTNIDVRTDFSGCLSQEWEAFLEESYPYFLIVADEGLNNLQTHLFNFLIIQSWALKINAVLFAGQVADVLRLYAYFMPSRHKNQMFFQKNRRTIENAYRSLIKQLEKCRALAFAPLFGNLKWENMMEEAHETISLLKQLWPEGSDIRRVLCVTSCSLSLRFYHQLLESRSETTAAHQQVEGKPLALQEVEDLCKLHCLSVAFLLCLPLSQRACTRFVTSHWIEDIQTFLKMKKCCDYFILSDVNISESWNLDLTHLSDLSDELLLKNIAFYYENENAQGLHLGNVITKDYEHLWDTVSKLVRPFDVGKPFPLRTTKRPFLKKNPSPIKDTSMEKMPSLGFIPMSCQVVDNFVGDILKDLPFLTSDDPVVTSLVKQKEFDELVHWHSHKPLSDDYDRTKCQFNEKSRDPYYLRSVQKYHVFQRFYGNSLESVSSKFVVTQGIKPRKFYGPTSKKTQETKAEIITRENKKRLLAKEEEKEEKKWSVLSFSIEEEMKEDLNSGIKNLEDFLKSCKSSSVKFRVEMVGLTACLKAWKEYCQSEGETTKDLSIAVQMMKRIYSVVEKYPELLQEADRQVIAKCLRYLGFEELASSLHLTQVAGNVTKEKRKNKYSVGIGPARFQLQYMGPYLLRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMERVLREGDDGVVVYVAPTKALVNQVAATVQNRFRKNLPDGEALCGVFTRDYRHDALNSQILITVPACFEILLLAPHRQAWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPEHLTEWLQSVKRYWKQADERMGQNIASRSVGCRPGSRKDCLLAKQSYRVRLVLYGERYNDLEKHICSVNNGVISFNHFHPCAALTTDHIEKYGFPSDLTLSPREMVQLYDTMFHFWAGWPRAQELCPEEFIHFKNKIVIKKSDTRKYEESLKAELTDWVKSGCVKQARMVLKHLRPGSVISSENMADMFPLLVEKLKQMEKLPALFFLFKLGAVEERARSVKTFLEKKQQRKRPPKADKEAHDMENKLRKVRKSIEKQKTIDEKSLKKPRNMDQSLIHEAEHDNLLKVLEKNLEIPQDCTYADQKALDAQTLQTVFDRVKLTRKGAELKALAARGVGYHHSSLNFKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFAQNSIYLDALNYRQMSGRAGRRGQDLLGDVYFFDIPLPKIEKLIKSNVPQLRGQFPLSISLVLRLMLLASKGDDPGDAQAKVLSVLKHSLLSFKQPRTLEMLKLYFLFALQFLVKEGYLDREGNPVGFAGLVSHLHYHEPSNLVFVSFLVRGLFHNLCQPTRKGSKLFSQDVMEKLVLVLANLFGRTYFPAKFHESPPKFYQSKVFLEDLPKDFKDALDQYNKNVTEDFASFLMIVSRLADMKQEYQLPLSHTDFSGEECEDSQLASYLMSCKEGRVAISPFVCLSGNSDGDLLCPGTLDHVTLRTIGISSSQAPVLCPQRFDNQGRKMPLNAYALDFYKHGSLTGLVQDNRMNEGLAYQLLKDFALTIQSISVSLRELCVNEEDNVVLAFEQLSKSFLEKFNKI", "length": 1704 }, "evidence": [ { "id": "A0A9J7J8F2", "url": "https://omabrowser.org/oma/group/A0A9J7J8F2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E9PZQ1-1", "protein_name": "DExD/H box helicase 60", "gene_name": "Ddx60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKKYTGFLKIMSHLILETMSKADYSSLFNDFVESEFFLIDGDSLLITCACERSLKPGQSLHFFYLVERYLLDVISKGGQFAIVFFKDAEYAYFNVPELLTLRTALILHLQKNTTVEVWTKFSNCLSEEWNICLGQSCPYFLILADEGLNDLQTHLFNFVVIQAWAAKVNIVLFSGQTSDILRLYAYFMQSSHGMQMFFKENKRMIMIVYKSLIQQLEKYRDMALAHLFGDLKFNDMEEKVCETVSLLKQLWPEGSDIRCVFCVTSCSLFLEMYHCYLESREKGASEEMSKVKQKTDNCLTLKDMEDFCKLHCLSVALLLHVPLSQRARSRFITANWIQDLKTVLKMKKWCEYFILSNLDMFESWSLNLLHLSDLSDEPLLRNIAFYYENENKEGLDLNVGDAIMNEYVHLWDTVSKLVRKFDVGKPIPLRTTKVHFLEKTPSPIKESSQEMMPNLGFIPMSCNLVDEFTGDILKDLPFLMSDDPIVTSLVKHKEFDELVHWHSHRPLSDDYDRTKCIGDANRRDPNHLKRLQKYHSFQRFYGESLESVTSKTITTQGPKPKKDCIKSKSTKAHETKAEIIKRENKKRLIAEEEQKEEQKWNALSFSIEEEMRKNVDSGMKKLEEFLKSCKSRSVKAQVERVGLQACLKAWKEHCQAEGETTKDLSIAVNMMKRIHSLLDKHSELLQEADQKLIARCLKYLGFCELAVSLYPTQDASDGIKMKKKNKYSVGIGPARFQLQYMGHYLIREERKDPDPRVQDFIPDTWQRELLDVVDNYESAVIVAPTSSGKTYASYYCMEKVLKESDEGVVVYVAPTKALVNQVAATVEYRYAKNMPAGESLCGVFTRDYRHDALNCQVLITVPACFEILLLAPHRQNWVKRIRYVIFDEVHCLGGEIGAEIWEHLLVMIRCPFLALSATISNPQHLTEWLQSVKRYWKQVDSTMEERTVSKRTGTSRGSYYKDQAQARQSYKVRLVLYGERYNDLEKYLCSVRQGDVCFDHFHPCAALTIDHIEKYGFPSDLALSPRESIQLYDTMCQVWKSWPQAQSLCPENFTQFKNKIVIKKLDARKYEESLKEEFTNWVKNGNEEEARMVLKKLSPDYHEHSGRMLDFFPCLVEKLRKMEKLPALFFLFKLNIVEECAENAFEFLEKKQEEKRPPKADKEARTTANKLRKVKKSLEKQKTVDEKGQKSSRRLDESVMHETEHNYLLQTLEKNLEIPKDCTYANQKAIDDQLLQRVFHRVRFERKGETLKRLAERGIGYHHSSMSAKEKQLVEILFRKGFIRVVTATGTLALGINMPCKSVVFAQNSVYLDALNYRQMSGRAGRRGQDLLGDVYFFDIPLPKIGKLIKSKVPELRGQFPLSISLILRLMLLASKADDLEDGKAKALSVLKHSLLSFKQPRAIDMLKLYFLYSLQFLVKEGHIDQEGNPTGFAGLVSHLHYHEPSNLVFVSFLVKGLFHKLCQPTREGPKRFSEDVMEKLVLVLANLFGRRYIPAKFYEVNSKFYQSKVFLDDLPEDFSHALLEYNTQVTEDFASFLLMVSRLADMKQEYQLSLSKIEFTGKECEDSPLVSHLMNCKEGRVAVSPFVCLSGNFDVDLLSPGVPNHVILHTLGINHTQAPVLWPYALDSQGRKIPLNAYALDFYKHGSLIGLVQDNRIHPGEAYSLLKDFNLIIKSISVSLRELCENEEDNVVLAFEQLSTSFQEKFELV", "length": 1711 }, "evidence": [ { "id": "A0A9J7J8F2", "url": "https://omabrowser.org/oma/group/A0A9J7J8F2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IY21-1", "protein_name": "Probable ATP-dependent RNA helicase DDX60", "gene_name": "DDX60", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8F2" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8F2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8F2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": 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"authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J7F7-1", "uniprot_ac": "A0A9J7J7F7", "uniprot_id": "A0A9J7J7F7_CRIGR", "mass": { "chemical_mass": 39764.0, "monoisotopic_mass": 39764.0 }, "refseq": { "ac": "XP_007653128", "name": "mitochondrial fission factor isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653128" }, "gene_names": [ { "name": "Mff", "type": "recommended", "evidence": [ { "id": "A0A9J7J7F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7" } ] }, { "name": "Mff", "type": "synonym", "evidence": [ { "id": "XP_007653128", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653128" } ] } ], "protein_names": [ { "name": "Mitochondrial fission factor", "type": "recommended", "evidence": [ { "id": "A0A9J7J7F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial fission factor isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007653128", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653128" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 246 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617096.1) and transcript sequence (IACG01087079.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007653128", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653128" } ] }, { "annotation": "Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F7P9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F7P9#function" }, { "database": "UniProtKB", "id": "ARBA00002338", "url": "https://www.uniprot.org/uniprotkb/ARBA00002338#function" }, { "database": "UniProtKB", "id": "A0A9J7F8G8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8G8#function" }, { "database": "UniProtKB", "id": "A0A9J7FBW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBW4#function" }, { "database": "UniProtKB", "id": "A0A9J7FC38", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC38#function" }, { "database": "UniProtKB", "id": "A0A9J7FCN2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCN2#function" }, { "database": "UniProtKB", "id": "A0A9J7K5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5Q1#function" }, { "database": "UniProtKB", "id": "A0A9J7J7F7", "url": 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{} } ], "crossref": [ { "id": "100772038", "url": "https://www.ncbi.nlm.nih.gov/gene/100772038", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772038", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772038", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7F8G8", "url": "https://www.orthodb.org/?gene=A0A9J7F8G8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FBW4", "url": "https://www.orthodb.org/?gene=A0A9J7FBW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FC38", "url": "https://www.orthodb.org/?gene=A0A9J7FC38", "database": "OrthoDB", 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF05644", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007653128", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653128", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7F7P9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F7P9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F7P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F7P9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F8G8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F8G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8G8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FBW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FBW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FC38", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FC38-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FCN2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FCN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GRP5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GRP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7F7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JCN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JCN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JCN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JCN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JCR9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JCR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JCR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JCR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JE60", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JE60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JE60-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JE60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKRTGSDTSLGRVSGAAFPSPTASEMAEISRIQYEMEYTEGISQRMRVPEKLKVAPPSADLDQGFQEGVPNASVIMQVPERIVVTGNNEDISFSRPADLDLIQSTPFKPLALKTPPRVLTLSERPLDFLDLERPPPTPQNEEIRAVGRLKRERSMSENAVRQNGQLVRNDSVWHRSDSAPRNKISRFQASISAPEYTVTPSPPQAPRVCPPHMLPEDGASLSSARGILSLIQSSTRRAYQQILDVLDENRSVRRQNEIRCERPVLRGGSAAATSNPHHDNVRYGISNIDAAIEGASDDMTVVDAASLRRQIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR", "length": 354, "header": "tr|A0A9J7J7F7-1|A0A9J7J7F7_CRIGR Isoform 1 of Mitochondrial fission factor OS=Cricetulus griseus OX=10029 GN=Mff PE=3 SV=1 CANONICAL=A0A9J7J7F7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F7P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7/entry#A0A9J7F7P9-1", "sequence": { "sequence": "MSKRTGSDTSLGRVSGAAFPSPTASEMAEISRIQYEMEYTEGISQRMRVPEKLKVAPPSADLDQGFQEGVPNASVIMQVPERIVVTGNNEDISFSRPADLDLIQSTPFKPLALKTPPRVLTLSERPLDFLDLERPPPTPQNEEIRAVGRLKRERSMSENAVRQNGQLVRNDSVWHRSDSAPRNKISRFQASISAPEYTPVLRGGSAAATSNPHHDNVRYGISNIDAAIEGASDDMTVVDAASLRRQIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR", "length": 289, "header": "tr|A0A9J7F7P9-1|A0A9J7J7F7_CRIGR Computationally mapped isoform of Mitochondrial fission factor OS=Cricetulus griseus OX=10029 GN=Mff PE=3 SV=1 CANONICAL=A0A9J7J7F7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F8G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7/entry#A0A9J7F8G8-1", "sequence": { "sequence": "MSKRTGSDTSLGRVSGAAFPSPTASEMAEISRIQYEMEYTEGISQRMRVPEKLKVAPPSADLDQGFQEGVPNASVIMQVPERIVVTGNNEDISFSRPADLDLIQSTPFKPLALKTPPRVLTLSERPLDFLDLERPPPTPQNEEIRAVGRLKRERSMSENAVRQNGQLVRNDSVVTPSPPQAPRVCPPHMLPEDGASLSSARGILSLIQSSTRRAYQQILDVLDENRRPVLRGGSAAATSNPHHDNVRYGISNIDAAIEGASDDMTVVDAASLRRQIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR", "length": 318, "header": "tr|A0A9J7F8G8-1|A0A9J7J7F7_CRIGR Computationally mapped isoform of Mitochondrial fission factor OS=Cricetulus griseus OX=10029 GN=Mff PE=3 SV=1 CANONICAL=A0A9J7J7F7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FBW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7/entry#A0A9J7FBW4-1", "sequence": { "sequence": "MSKRTGSDTSLGRVSGAAFPSPTASEMAEISRIQYEMEYTEGISQRMRVPEKLKVAPPSADLDQGFQEGVPNASVIMQVPERIVVTGNNEDISFSRPADLDLIQSTPFKPLALKTPPRVLTLSERPLDFLDLERPPPTPQNEEIRAVGRLKRERSMSENAVRQNGQLVRNDSVYGISNIDAAIEGASDDMTVVDAASLRRQIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR", "length": 244, "header": "tr|A0A9J7FBW4-1|A0A9J7J7F7_CRIGR Computationally mapped isoform of Mitochondrial fission factor OS=Cricetulus griseus OX=10029 GN=Mff PE=3 SV=1 CANONICAL=A0A9J7J7F7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FC38-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7/entry#A0A9J7FC38-1", "sequence": { "sequence": "MSKRTGSDTSLGRVSGAAFPSPTASEMAEISRIQYEMEYTEGISQRMRVPEKLKVAPPSADLDQGFQEGVPNASVIMQVPERIVVTGNNEDISFSRPADLDLIQSTPFKPLALKTPPRVLTLSERPLDFLDLERPPPTPQNEEIRAVGRLKRERSMSENAVRQNGQLVRNDSVWHRSDSAPRNKISRFQASISAPEYTVRRQNEIRCERPVLRGGSAAATSNPHHDNVRYGISNIDAAIEGASDDMTVVDAASLRRQIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR", "length": 300, "header": "tr|A0A9J7FC38-1|A0A9J7J7F7_CRIGR Computationally mapped isoform of Mitochondrial fission factor OS=Cricetulus griseus OX=10029 GN=Mff PE=3 SV=1 CANONICAL=A0A9J7J7F7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FCN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7/entry#A0A9J7FCN2-1", "sequence": { "sequence": "MSKRTGSDTSLGRVSGAAFPSPTASEMAEISRIQYEMEYTEGISQRMRVPEKLKVAPPSADLDQGFQEGVPNASVIMQVPERIVVTGNNEDISFSRPADLDLIQSTPFKPLALKTPPRVLTLSERPLDFLDLERPPPTPQNEEIRAVGRLKRERSMSENAVRQNGQLVRNDSVWHRSDSAPRNKISRFQASISAPEYTYGISNIDAAIEGASDDMTVVDAASLRRQIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR", "length": 269, "header": "tr|A0A9J7FCN2-1|A0A9J7J7F7_CRIGR Computationally mapped isoform of Mitochondrial fission factor OS=Cricetulus griseus OX=10029 GN=Mff PE=3 SV=1 CANONICAL=A0A9J7J7F7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GRP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7/entry#A0A9J7GRP5-1", "sequence": { "sequence": "MAEISRIQYEMEYTEGISQRMRVPEKLKVAPPSADLDQGFQEGVPNASVIMQVPERIVVTGNNEDISFSRPADLDLIQSTPFKPLALKTPPRVLTLSERPLDFLDLERPPPTPQNEEIRAVGRLKRERSMSENAVRQNGQLVRNDSVWHRSDSAPRNKISRFQASISAPEYTVTPSPPQAPRVCPPHMLPEDGASLSSARGILSLIQSSTRRAYQQILDVLDENRSVRRQNEIRCERPVLRGGSAAATSNPHHDNVRYGISNIDAAIEGASDDMTVVDAASLRRQIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR", "length": 328, "header": "tr|A0A9J7GRP5-1|A0A9J7GRP5_CRIGR Computationally mapped isoform of Mitochondrial fission factor OS=Cricetulus griseus OX=10029 GN=Mff PE=3 SV=1 CANONICAL=A0A9J7J7F7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J7F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7/entry#A0A9J7J7F7-1", "sequence": { "sequence": "MSKRTGSDTSLGRVSGAAFPSPTASEMAEISRIQYEMEYTEGISQRMRVPEKLKVAPPSADLDQGFQEGVPNASVIMQVPERIVVTGNNEDISFSRPADLDLIQSTPFKPLALKTPPRVLTLSERPLDFLDLERPPPTPQNEEIRAVGRLKRERSMSENAVRQNGQLVRNDSVWHRSDSAPRNKISRFQASISAPEYTVTPSPPQAPRVCPPHMLPEDGASLSSARGILSLIQSSTRRAYQQILDVLDENRSVRRQNEIRCERPVLRGGSAAATSNPHHDNVRYGISNIDAAIEGASDDMTVVDAASLRRQIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR", "length": 354, "header": "tr|A0A9J7J7F7-1|A0A9J7J7F7_CRIGR Isoform 1 of Mitochondrial fission factor OS=Cricetulus griseus OX=10029 GN=Mff PE=3 SV=1 CANONICAL=A0A9J7J7F7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JCN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7/entry#A0A9J7JCN1-1", "sequence": { "sequence": "MSKRTGSDTSLGRVSGAAFPSPTASEMAEISRIQYEMEYTEGISQRMRVPEKLKVAPPSADLDQGFQEGVPNASVIMQVPERIVVTGNNEDISFSRPADLDLIQSTPFKPLALKTPPRVLTLSERPLDFLDLERPPPTPQNEEIRAVGRLKRERSMSENAVRQNGQLVRNDSVVTPSPPQAPRVCPPHMLPEDGASLSSARGILSLIQSSTRRAYQQILDVLDENRSVRRQNEIRCERPVLRGGSAAATSNPHHDNVRYGISNIDAAIEGASDDMTVVDAASLRRQIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR", "length": 329, "header": "tr|A0A9J7JCN1-1|A0A9J7JCN1_CRIGR Computationally mapped isoform of Mitochondrial fission factor OS=Cricetulus griseus OX=10029 GN=Mff PE=3 SV=1 CANONICAL=A0A9J7J7F7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JCR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7/entry#A0A9J7JCR9-1", "sequence": { "sequence": "MSKRTGSDTSLGRVSGAAFPSPTASEMAEISRIQYEMEYTEGISQRMRVPEKLKVAPPSADLDQGFQEGVPNASVIMQVPERIVVTGNNEDISFSRPADLDLIQSTPFKPLALKTPPRVLTLSERPLDFLDLERPPPTPQNEEIRAVGRLKRERSMSENAVRQNGQLVRNDSVWHRSDSAPRNKISRFQASISAPEYTVTPSPPQAPRVCPPHMLPEDGASLSSARGILSLIQSSTRRAYQQILDVLDENRRPVLRGGSAAATSNPHHDNVRYGISNIDAAIEGASDDMTVVDAASLRRQIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR", "length": 343, "header": "tr|A0A9J7JCR9-1|A0A9J7JCR9_CRIGR Computationally mapped isoform of Mitochondrial fission factor OS=Cricetulus griseus OX=10029 GN=Mff PE=3 SV=1 CANONICAL=A0A9J7J7F7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JE60-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7/entry#A0A9J7JE60-1", "sequence": { "sequence": "MSKRTGSDTSLGRVSGAAFPSPTASEMAEISRIQYEMEYTEGISQRMRVPEKLKVAPPSADLDQGFQEGVPNASVIMQVPERIVVTGNNEDISFSRPADLDLIQSTPFKPLALKTPPRVLTLSERPLDFLDLERPPPTPQNEEIRAVGRLKRERSMSENAVRQNGQLVRNDSVPVLRGGSAAATSNPHHDNVRYGISNIDAAIEGASDDMTVVDAASLRRQIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR", "length": 264, "header": "tr|A0A9J7JE60-1|A0A9J7JE60_CRIGR Computationally mapped isoform of Mitochondrial fission factor OS=Cricetulus griseus OX=10029 GN=Mff PE=3 SV=1 CANONICAL=A0A9J7J7F7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K5Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7/entry#A0A9J7K5Q1-1", "sequence": { "sequence": "MSKRTGSDTSLGRVSGAAFPSPTASEMAEISRIQYEMEYTEGISQRMRVPEKLKVAPPSADLDQGFQEGVPNASVIMQVPERIVVTGNNEDISFSRPADLDLIQSTPFKPLALKTPPRVLTLSERPLDFLDLERPPPTPQNEEIRAVGRLKRERSMSENAVRQNGQLVRNDSVVRRQNEIRCERPVLRGGSAAATSNPHHDNVRYGISNIDAAIEGASDDMTVVDAASLRRQIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR", "length": 275, "header": "tr|A0A9J7K5Q1-1|A0A9J7J7F7_CRIGR Computationally mapped isoform of Mitochondrial fission factor OS=Cricetulus griseus OX=10029 GN=Mff PE=3 SV=1 CANONICAL=A0A9J7J7F7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 138, "start_aa": "Thr", "end_pos": 138, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr138", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F7P9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F7P9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F7P9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F7P9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772038", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772038", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7F7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7F7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein targeting to mitochondrion", "id": "GO:0006626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006626", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7F7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7" } ], "pmid": "" }, { "name": "positive regulation of protein targeting to membrane", "id": "GO:0090314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090314", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7F7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7" } ], "pmid": "" }, { "name": "mitochondrial fission", "id": "GO:0000266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000266", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7F7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial fission", "id": "GO:0090141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090141", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7F7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J7F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F7" }, { "id": "PF05644", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05644" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mff-like", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 354, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 138 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 170, "end_pos": 172 }, { "start_pos": 250, "end_pos": 252 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J8Q3-1", "uniprot_ac": "A0A9J7J8Q3", "uniprot_id": "A0A9J7J8Q3_CRIGR", "mass": { "chemical_mass": 237144.0, "monoisotopic_mass": 237144.0 }, "refseq": { "ac": "XP_027255401", "name": "AT-rich interactive domain-containing protein 1A isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255401" }, "gene_names": [ { "name": "Arid1a", "type": "recommended", "evidence": [ { "id": "A0A9J7J8Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Q3" } ] }, { "name": "Arid1a", "type": "synonym", "evidence": [ { "id": "XP_027255401", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255401" } ] } ], "protein_names": [ { "name": "AT-rich interactive domain-containing protein 1A isoform X5", "type": "synonym", "evidence": [ { "id": "XP_027255401", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255401" }, { "id": "A0A9J7J8Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Q3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027255401.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027255401", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255401" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Q3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Arid1a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Q3", "locus": {} } ], "crossref": [ { "id": "cd16876", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16876", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771997", "url": "https://www.ncbi.nlm.nih.gov/gene/100771997", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771997", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771997", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FBC7", "url": "https://www.orthodb.org/?gene=A0A9J7FBC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J8Q3", "url": "https://www.orthodb.org/?gene=A0A9J7J8Q3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12656:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12656:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027255401", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255401", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FBC7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FBC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JE95", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JE95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JE95-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JE95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGGGGGGGGGAGAEPDLKNSNGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPPQAYALSSPRGGTPGSGAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYGGGPQDGGAGKGPADMASQCWGAAAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYTQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYAQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQTQQPQLQSSQPPYSQQPSQPPHQQSPTPYPSQQSTAQQHPQSQPPYSQPQAQSPYQQQQPQQPASSTLSQQAAYPQPQPQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYTSPQPGSALSPRQPSGGQMHTGMGSYQQNSMGSYGPQGSQYGPQGGYPRQPNYNALPNANYPNAGMAGSMNPMGAGGQMHGQPGIPPYGTLPPGRMTHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQESAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYPMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFPDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMGTGAPQPNLMPSTADSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSSSPFPSQQATLYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPTAQSQSASQQQAAQPSPQQDVYNQYSNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGSNAQQNMPPQMMGGPMQSSAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQSAAYHGVNRTDEMLHTDQRANHEGPWPSHGTRQPPYGPSAPVPPMTRPSPSNYQPPPSIQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQKRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFSLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPSPTEEEEEDLLEPKLEEEGEVVENDEELAFLGKDKPASENSEEKLVSKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKVELLPSRPYMPCPTPPRKHLTTIEGTQGTAEQEGPPPDGLPEKRITATMDDMLSTRSSTLTDEGTKSAEATKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCDKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 2234, "header": "tr|A0A9J7J8Q3-1|A0A9J7J8Q3_CRIGR Isoform 1 of AT-rich interactive domain-containing protein 1A isoform X5 OS=Cricetulus griseus OX=10029 GN=Arid1a PE=4 SV=1 CANONICAL=A0A9J7J8Q3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FBC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Q3/entry#A0A9J7FBC7-1", "sequence": { "sequence": "MDQMGKMRPQPYGGTNPYTQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYAQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQTQQPQLQSSQPPYSQQPSQPPHQQSPTPYPSQQSTAQQHPQSQPPYSQPQAQSPYQQQQPQQPASSTLSQQAAYPQPQPQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYTSPQPGSALSPRQPSGGQMHTGMGSYQQNSMGSYGPQGSQYGPQGGYPRQPNYNALPNANYPNAGMAGSMNPMGAGGQMHGQPGIPPYGTLPPGRMTHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQESAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYPMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFPDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMGTGAPQPNLMPSTADSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSSSPFPSQQATLYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPTAQSQSASQQQAAQPSPQQDVYNQYSNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGSNAQQNMPPQMMGGPMQSSAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQSAAYHGVNRTDEMLHTDQRANHEGPWPSHGTRQPPYGPSAPVPPMTRPSPSNYQPPPSIQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQKRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFSLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPSPTEEEEEDLLEPKLEEEGEVVENDEELAFLGKDKPASENSEEKLVSKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKVELLPSRPYMPCPTPPRKHLTTIEGTQGTAEQEGPPPDGLPEKRITATMDDMLSTRSSTLTDEGTKSAEATKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCDKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 1898, "header": "tr|A0A9J7FBC7-1|A0A9J7J8Q3_CRIGR Computationally mapped isoform of AT-rich interactive domain-containing protein 1A isoform X5 OS=Cricetulus griseus OX=10029 GN=Arid1a PE=4 SV=1 CANONICAL=A0A9J7J8Q3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J8Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Q3/entry#A0A9J7J8Q3-1", "sequence": { "sequence": "MKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGGGGGGGGGAGAEPDLKNSNGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPPQAYALSSPRGGTPGSGAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYGGGPQDGGAGKGPADMASQCWGAAAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYTQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYAQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQTQQPQLQSSQPPYSQQPSQPPHQQSPTPYPSQQSTAQQHPQSQPPYSQPQAQSPYQQQQPQQPASSTLSQQAAYPQPQPQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYTSPQPGSALSPRQPSGGQMHTGMGSYQQNSMGSYGPQGSQYGPQGGYPRQPNYNALPNANYPNAGMAGSMNPMGAGGQMHGQPGIPPYGTLPPGRMTHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQESAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYPMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFPDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMGTGAPQPNLMPSTADSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSSSPFPSQQATLYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPTAQSQSASQQQAAQPSPQQDVYNQYSNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGSNAQQNMPPQMMGGPMQSSAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQSAAYHGVNRTDEMLHTDQRANHEGPWPSHGTRQPPYGPSAPVPPMTRPSPSNYQPPPSIQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQKRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFSLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPSPTEEEEEDLLEPKLEEEGEVVENDEELAFLGKDKPASENSEEKLVSKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKVELLPSRPYMPCPTPPRKHLTTIEGTQGTAEQEGPPPDGLPEKRITATMDDMLSTRSSTLTDEGTKSAEATKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCDKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", 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"length": 2233, "header": "tr|A0A9J7JE95-1|A0A9J7JE95_CRIGR Computationally mapped isoform of AT-rich interactive domain-containing protein 1A isoform X4 OS=Cricetulus griseus OX=10029 GN=Arid1a PE=4 SV=1 CANONICAL=A0A9J7J8Q3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1301, "start_aa": "Thr", "end_pos": 1301, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1301", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1825, "start_aa": "Thr", "end_pos": 1825, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1825", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 190, "start_aa": "Thr", "end_pos": 190, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr190", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FBC7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBC7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FBC7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBC7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771997", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771997", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Q3" } ], "pmid": "" }, { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Q3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Q3" } ], "pmid": "" }, { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Q3" } ], "pmid": "" }, { "name": "nBAF complex", "id": "GO:0071565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071565", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Q3" } ], "pmid": "" }, { "name": "brahma complex", "id": "GO:0035060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035060", "evidence": [ { "database": "UniProtKB", "id": 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##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 319 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614478.1) and transcript sequence (IACG01089721.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007646924.1. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IEF9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEF9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769126", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769126", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "positive regulation of glucose mediated signaling pathway", "id": "GO:1902661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902661", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8J1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8J1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HD71-1", "uniprot_ac": "A0A9J7HD71", "uniprot_id": "A0A9J7HD71_CRIGR", "mass": { "chemical_mass": 145524.0, "monoisotopic_mass": 145524.0 }, "refseq": { "ac": "XP_035308485", "name": "adhesion G protein-coupled receptor L3 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308485" }, "gene_names": [ { "name": "Adgrl3", "type": "recommended", "evidence": [ { "id": "A0A9J7HD71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71" } ] }, { "name": "Adgrl3", "type": "synonym", "evidence": [ { "id": "XP_035308485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308485" } ] } ], "protein_names": [ { "name": "Adhesion G protein-coupled receptor L3 isoform X5", "type": "synonym", "evidence": [ { "id": "A0A9J7HD71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71/entry#names_and_taxonomy" } ] }, { "name": "adhesion G protein-coupled receptor L3 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_035308485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308485" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308485", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308485" } ] }, { "annotation": "Orphan adhesion G-protein coupled receptor (aGPCR), which mediates synapse specificity. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. Isoform 1 is specifically coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. Following G-protein coupled receptor activation, undergoes liquid-liquid phase transition, associates with (1) cell adhesion molecules that are expressed at the surface of adjacent cells, as well as (2) PDZ-containing proteins, such as SHANK3 and DLG4, in the cytoplasm to direct synapse formation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K447", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K447#function" }, { "database": "UniProtKB", "id": "ARBA00093322", "url": "https://www.uniprot.org/uniprotkb/ARBA00093322#function" }, { "database": "UniProtKB", "id": "A0A9J7KC04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC04#function" }, { "database": "UniProtKB", "id": "A0A9J7KE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE86#function" }, { "database": "UniProtKB", "id": "A0A9J7KF91", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KF91#function" }, { "database": "UniProtKB", "id": "A0A9J7HCX0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD71", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Adgrl3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71", "locus": {} } ], "crossref": [ { "id": "cd16005", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16005", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22846", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22846", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757140", "url": "https://www.ncbi.nlm.nih.gov/gene/100757140", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003334", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003334", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003924", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003924", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032471", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032471", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757140", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757140", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HD71", "url": "https://www.orthodb.org/?gene=A0A9J7HD71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12011", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12011", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12011:SF60", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12011:SF60", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02793", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02793", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16489", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16489", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308485", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308485", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HAW7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCX0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HD71", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HD71-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDX8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HF27", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HF27-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K447", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K447", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K447-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K447-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KC04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KC04-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KE86-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KF59", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KF59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KF59-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KF59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KF91", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KF91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KF91-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KF91-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGPVHHGQVSYISPPIHLDSDLERPPVRGISTTGPLGMGSTTTSTTLRTTTWNPGRSTTPSLPGRRNRSTSTPSPAVEVLDDITTHLPSAASQIPAVEESCEAVEAREIMWFKTRQGQVAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGETAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERSCRAYVQAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLDTVEESAFVLADNLLKTDIVRENTDNIQLEVARLSTEGNLEDLKFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEAMSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGSRTPGRYSTGSQSRIRRMWNDTVRKQSESSFITGDINSSASLNREPYRETKGLLNNARDTSVMDTLPLNGNHGNSYSIAGGEYLSNCVQIIDRGYNHNETALEKKILKELTSNYIPSYLNNHERSSEQNRNMMNKLVNNLGSGSEDDAIVLDDATSFNHEESLGLELIHEESDAPLLPPRVYSTENHQPHHYSRRRLPQDHSESFFPLLTDEHTEDLQSPHRDSLYTSMPALAGVPTADSVTASTQTEAAAAKGGDAEDVYYKSMPNLGSRNHVHPLHAYYQLGRGSSEGFIVPPNKDGASPEGTSKGPAHLVTSL", "length": 1304, "header": "tr|A0A9J7HD71-1|A0A9J7HD71_CRIGR Isoform 1 of Adhesion G protein-coupled receptor L3 isoform X5 OS=Cricetulus griseus OX=10029 GN=Adgrl3 PE=3 SV=1 CANONICAL=A0A9J7HD71-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HAW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71/entry#A0A9J7HAW7-1", "sequence": { "sequence": "MPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGPVHHGQVSYISPPIHLDSDLERPPVRGISTTGPLGMGSTTTSTTLRTTTWNPGRSTTPSLPGRRNRSTSTPSPAVEVLDDITTHLPSAASQIPAVEESCEAVEAREIMWFKTRQGQVAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGETAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLDTVEESAFVLADNLLKTDIVRENTDNIQLEVARLSTEGNLEDLKFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEAMSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGSRTPGRYSTGSQSRIRRMWNDTVRKQSESSFITGDINSSASLNREGLLNNARDTSVMDTLPLNGNHGNSYSIAGGEYLSNCVQIIDRGYNHNETALEKKILKELTSNYIPSYLNNHERSSEQNRNMMNKLVNNLGSGSEDDAIVLDDATSFNHEESLGLELIHEESDAPLLPPRVYSTENHQPHHYSRRRLPQDHSESFFPLLTDEHTEDLQSPHRDSLYTSMPALAGVPTADSVTASTQTEAAAAKGGDAEDVYYKSMPNLGSRNHVHPLHAYYQLGRGSSEGFIVPPNKDGASPEGTSKGPAHLVTSL", "length": 1276, "header": "tr|A0A9J7HAW7-1|A0A9J7HD71_CRIGR Computationally mapped isoform of Adhesion G protein-coupled receptor L3 isoform X5 OS=Cricetulus griseus OX=10029 GN=Adgrl3 PE=3 SV=1 CANONICAL=A0A9J7HD71-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HBJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71/entry#A0A9J7HBJ5-1", "sequence": { "sequence": "MPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGPVHHGQVSYISPPIHLDSDLERPPVRGISTTGPLGMGSTTTSTTLRTTTWNPGRSTTPSLPGRRNRSTSTPSPAVEVLDDITTHLPSAASQIPAVEESCEAVEAREIMWFKTRQGQVAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGETAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERSCRAYVQAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLDTVEESAFVLADNLLKTDIVRENTDNIQLEVARLSTEGNLEDLKFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEAMSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGSRTPGRYSTGSQSRIRRMWNDTVRKQSESSFITGDINSSASLNREGLLNNARDTSVMDTLPLNGNHGNSYSIAGGEYLSNCVQIIDRGYNHNETALEKKILKELTSNYIPSYLNNHERSSEQNRNMMNKLVNNLGSGSEDDAIVLDDATSFNHEESLGLELIHEESDAPLLPPRVYSTENHQPHHYSRRRLPQDHSESFFPLLTDEHTEDLQSPHRDSLYTSMPALAGVPTADSVTASTQTEAAAAKGGDAEDVYYKSMPNLGSRNHVHPLHAYYQLGRGSSEGFIVPPNKDGASPEGTSKGPAHLVTSL", "length": 1297, "header": "tr|A0A9J7HBJ5-1|A0A9J7HD71_CRIGR Computationally mapped isoform of Adhesion G protein-coupled receptor L3 isoform X5 OS=Cricetulus griseus OX=10029 GN=Adgrl3 PE=3 SV=1 CANONICAL=A0A9J7HD71-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HCX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71/entry#A0A9J7HCX0-1", "sequence": { "sequence": "MAVVRRELSCESYPIELRCPGTDVIMIESANYGRTDDKICDSDPAQMENIRCYLPDAYKIMSQRCNNRTQCAVVAGPDVFPDPCPGTYKYLEVQYECVPYKVEQKVFLCPGLLKGVYQSEHLFESDHQSGAWCKDPLQASDKIYYMPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGPVHHGQVSYISPPIHLDSDLERPPVRGISTTGPLGMGSTTTSTTLRTTTWNPGRSTTPSLPGRRNRSTSTPSPAVEVLDDITTHLPSAASQIPAVEESCEAVEAREIMWFKTRQGQVAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGETAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERSCRAYVQAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLDTVEESAFVLADNLLKTDIVRENTDNIQLEVARLSTEGNLEDLKFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEAMSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGSRTPGRYSTGSQSRIRRMWNDTVRKQSESSFITGDINSSASLNREPYRETSMGVKLNIAYQIGASEQCQGYKCHGYSTTEW", "length": 1214, "header": "tr|A0A9J7HCX0-1|A0A9J7HCX0_CRIGR Computationally mapped isoform of Adhesion G protein-coupled receptor L3 OS=Cricetulus griseus OX=10029 GN=Adgrl3 PE=3 SV=1 CANONICAL=A0A9J7HD71-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HD71-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71/entry#A0A9J7HD71-1", "sequence": { "sequence": "MPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGPVHHGQVSYISPPIHLDSDLERPPVRGISTTGPLGMGSTTTSTTLRTTTWNPGRSTTPSLPGRRNRSTSTPSPAVEVLDDITTHLPSAASQIPAVEESCEAVEAREIMWFKTRQGQVAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGETAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERSCRAYVQAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLDTVEESAFVLADNLLKTDIVRENTDNIQLEVARLSTEGNLEDLKFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEAMSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGSRTPGRYSTGSQSRIRRMWNDTVRKQSESSFITGDINSSASLNREPYRETKGLLNNARDTSVMDTLPLNGNHGNSYSIAGGEYLSNCVQIIDRGYNHNETALEKKILKELTSNYIPSYLNNHERSSEQNRNMMNKLVNNLGSGSEDDAIVLDDATSFNHEESLGLELIHEESDAPLLPPRVYSTENHQPHHYSRRRLPQDHSESFFPLLTDEHTEDLQSPHRDSLYTSMPALAGVPTADSVTASTQTEAAAAKGGDAEDVYYKSMPNLGSRNHVHPLHAYYQLGRGSSEGFIVPPNKDGASPEGTSKGPAHLVTSL", "length": 1304, "header": "tr|A0A9J7HD71-1|A0A9J7HD71_CRIGR Isoform 1 of Adhesion G protein-coupled receptor L3 isoform X5 OS=Cricetulus griseus OX=10029 GN=Adgrl3 PE=3 SV=1 CANONICAL=A0A9J7HD71-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HDX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71/entry#A0A9J7HDX8-1", "sequence": { "sequence": "MPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGPVHHGQVSYISPPIHLDSDLERPPVRGISTTGPLGMGSTTTSTTLRTTTWNPGRSTTPSLPGRRNRSTSTPSPAVEVLDDITTHLPSAASQIPAVEESCEAVEAREIMWFKTRQGQVAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGETAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERSCRAYVQAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLDTVEESAFVLADNLLKTDIVRENTDNIQLEVARLSTEGNLEDLKFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEAMSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGSRTPGRYSTGSQSRIRRMWNDTVRKQSESSFITGDINSSASLNREGLLNNARDTSVMDTLPLNGNHGNSYSIAGGEYLSNCVQIIDRGYNHNETALEKKILKELTSNYIPSYLNNHERSSEQNRNMMNKLVNNLGSGSEDDAIVLDDATSFNHEESLGLELIHEESDAPLLPPRVYSTENHQPHHYSRRRLPQDHSESFFPLLTDEHTEDLQSPHRDSLYTSMPALAGVPTADSVTASTQTEAAAAKGGDAEDVYYKSMPNLGSRNHVHPLHAYYQLGRGSSEGFIVPPNKDGASPEGTSKGPAHLVTSL", "length": 1289, "header": "tr|A0A9J7HDX8-1|A0A9J7HDX8_CRIGR Computationally mapped isoform of Adhesion G protein-coupled receptor L3 isoform X4 OS=Cricetulus griseus OX=10029 GN=Adgrl3 PE=3 SV=1 CANONICAL=A0A9J7HD71-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HF27-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71/entry#A0A9J7HF27-1", "sequence": { "sequence": "MPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGPVHHGQVSYISPPIHLDSDLERPPVRGPLGMGSTTTSTTLRTTTWNPGRSTTPSLPGRRNRSTSTPSPAVEVLDDITTHLPSAASQIPAVEESCEAVEAREIMWFKTRQGQVAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGETAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLDTVEESAFVLADNLLKTDIVRENTDNIQLEVARLSTEGNLEDLKFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEAMSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGSRTPGRYSTGSQSRIRRMWNDTVRKQSESSFITGDINSSASLNREGLLNNARDTSVMDTLPLNGNHGNSYSIAGGEYLSNCVQIIDRGYNHNETALEKKILKELTSNYIPSYLNNHERSSEQNRNMMNKLVNNLGSGSEDDAIVLDDATSFNHEESLGLELIHEESDAPLLPPRVYSTENHQPHHYSRRRLPQDHSESFFPLLTDEHTEDLQSPHRDSLYTSMPALAGVPTADSVTASTQTEAAAAKGGDAEDVYYKSMPNLGSRNHVHPLHAYYQLGRGSSEGFIVPPNKDGASPEGTSKGPAHLVTSL", "length": 1271, "header": "tr|A0A9J7HF27-1|A0A9J7HF27_CRIGR Computationally mapped isoform of Adhesion G protein-coupled receptor L3 isoform X7 OS=Cricetulus griseus OX=10029 GN=Adgrl3 PE=3 SV=1 CANONICAL=A0A9J7HD71-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K447-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71/entry#A0A9J7K447-1", "sequence": { "sequence": "MAVVRRELSCESYPIELRCPGTDVIMIESANYGRTDDKICDSDPAQMENIRCYLPDAYKIMSQRCNNRTQCAVVAGPDVFPDPCPGTYKYLEVQYECVPYKVEQKVFLCPGLLKGVYQSEHLFESDHQSGAWCKDPLQASDKIYYMPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGPVHHGQVSYISPPIHLDSDLERPPVRGISTTGPLGMGSTTTSTTLRTTTWNPGRSTTPSLPGRRNRSTSTPSPAVEVLDDITTHLPSAASQIPAVEESCEAVEAREIMWFKTRQGQVAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGETAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERSCRAYVQAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLDTVEESAFVLADNLLKTDIVRENTDNIQLEVARLSTEGNLEDLKFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEAMSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGSRTPGRYSTGSQSRIRRMWNDTVRKQSESSFITGDINSSASLNREPYRETSMGVKLNIAYQIGASEQCQGYKCHGYSTTEW", "length": 1205, "header": "tr|A0A9J7K447-1|A0A9J7HD71_CRIGR Computationally mapped isoform of Adhesion G protein-coupled receptor L3 isoform X5 OS=Cricetulus griseus OX=10029 GN=Adgrl3 PE=3 SV=1 CANONICAL=A0A9J7HD71-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KC04-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71/entry#A0A9J7KC04-1", "sequence": { "sequence": "MAVVRRELSCESYPIELRCPGTDVIMIESANYGRTDDKICDSDPAQMENIRCYLPDAYKIMSQRCNNRTQCAVVAGPDVFPDPCPGTYKYLEVQYECVPYIFLCPGLLKGVYQSEHLFESDHQSGAWCKDPLQASDKIYYMPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGPVHHGQVSYISPPIHLDSDLERPPVRGISTTGPLGMGSTTTSTTLRTTTWNPGRSTTPSLPGRRNRSTSTPSPAVEVLDDITTHLPSAASQIPAVEESCEAVEAREIMWFKTRQGQVAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGETAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERSCRAYVQAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLDTVEESAFVLADNLLKTDIVRENTDNIQLEVARLSTEGNLEDLKFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEAMSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGSRTPGRYSTGSQSRIRRMWNDTVRKQSESSFITGDINSSASLNREPYRETSMGVKLNIAYQIGASEQCQGYKCHGYSTTEW", "length": 1209, "header": "tr|A0A9J7KC04-1|A0A9J7HD71_CRIGR Computationally mapped isoform of Adhesion G protein-coupled receptor L3 isoform X5 OS=Cricetulus griseus OX=10029 GN=Adgrl3 PE=3 SV=1 CANONICAL=A0A9J7HD71-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KE86-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71/entry#A0A9J7KE86-1", "sequence": { "sequence": "MAVVRRELSCESYPIELRCPGTDVIMIESANYGRTDDKICDSDPAQMENIRCYLPDAYKIMSQRCNNRTQCAVVAGPDVFPDPCPGTYKYLEVQYECVPYIFLCPGLLKGVYQSEHLFESDHQSGAWCKDPLQASDKIYYMPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGPVHHGQVSYISPPIHLDSDLERPPVRGISTTGPLGMGSTTTSTTLRTTTWNPGRSTTPSLPGRRNRSTSTPSPAVEVLDDITTHLPSAASQIPAVEESCEAVEAREIMWFKTRQGQVAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGETAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERSCRAYVQAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLDTVEESAFVLADNLLKTDIVRENTDNIQLEVARLSTEGNLEDLKFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEAMSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGSRTPGRYSTGSQSRIRRMWNDTVRKQSESSFITGDINSSASLNREPYRETSMGVKLNIAYQIGASEQCQGYKCHGYSTTEW", "length": 1200, "header": "tr|A0A9J7KE86-1|A0A9J7HD71_CRIGR Computationally mapped isoform of Adhesion G protein-coupled receptor L3 isoform X5 OS=Cricetulus griseus OX=10029 GN=Adgrl3 PE=3 SV=1 CANONICAL=A0A9J7HD71-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KF59-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71/entry#A0A9J7KF59-1", "sequence": { "sequence": "MPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGPVHHGQVSYISPPIHLDSDLERPPVRGISTTGPLGMGSTTTSTTLRTTTWNPGRSTTPSLPGRRNRSTSTPSPAVEVLDDITTHLPSAASQIPAVEESCEAVEAREIMWFKTRQGQVAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGETAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERSCRAYVQAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLDTVEESAFVLADNLLKTDIVRENTDNIQLEVARLSTEGNLEDLKFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEAMSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGSRTPGRYSTGSQSRIRRMWNDTVRKQSESSFITGDINSSASLNREGLLNNARDTSVMDTLPLNGNHGNSYSIAGGEYLSNCVQIIDRGYNHNETALEKKILKELTSNYIPSYLNNHERSSEQNRNMMNKLVNNLGSGSEDDAIVLDDATSFNHEESLGLELIHEESDAPLLPPRVYSTENHQPHHYSRRRLPQDHSESFFPLLTDEHTEDLQSPHRDSLYTSMPALAGVPTADSVTASTQTEAAAAKGGDAEDVYYKSMPNLGSRNHVHPLHAYYQLGRGSSEGFIVPPNKDGASPEGTSKGPAHLVTSL", "length": 1298, "header": "tr|A0A9J7KF59-1|A0A9J7HD71_CRIGR Computationally mapped isoform of Adhesion G protein-coupled receptor L3 isoform X5 OS=Cricetulus griseus OX=10029 GN=Adgrl3 PE=3 SV=1 CANONICAL=A0A9J7HD71-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KF91-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD71/entry#A0A9J7KF91-1", "sequence": { "sequence": 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Computationally mapped isoform of diphthine methyl ester synthase OS=Cricetulus griseus OX=10029 GN=LOC100755934 PE=3 SV=1 CANONICAL=A0A9J7J6E4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J6E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6E4/entry#A0A9J7J6E4-1", "sequence": { "sequence": "MVLDLLLQKGYSETLRGVSEASTSPSAVSPSLEFEMLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLILADREEVEQEADNIFKDADVSDVAFLVVGDPFGATTHSDLILRATKLGIPYQVIHNASIMNAVGCCGLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIRGRKIYEPPRYMSVNQAAQQLLEIVQNQRARGEEPAITEETLCVGLARVGAEDQKIAAGTLQQMCTVDLGEPLHSLVITGGTLHPLEMEMLSLFSIPESQSINGL", "length": 316, "header": "tr|A0A9J7J6E4-1|A0A9J7J6E4_CRIGR Isoform 1 of diphthine methyl ester synthase OS=Cricetulus griseus OX=10029 GN=LOC100755934 PE=3 SV=1 CANONICAL=A0A9J7J6E4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LPU6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPU6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LPU6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPU6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755934", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755934", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "diphthine synthase activity", "id": "GO:0004164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004164", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6E4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6E4" } ], "pmid": "" }, { "name": "diphthine methyl ester synthase activity", "id": "GO:0141133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141133", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6E4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6E4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6E4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6E4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6E4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6E4" } ], "pmid": "" }, { "name": "protein histidyl modification to diphthamide", "id": "GO:0017183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017183", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6E4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6E4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027242912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242912" } ] }, { "annotation": "Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans. May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. 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"categories": [ "Protein Classification" ] }, { "id": "PTHR22939", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22939", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22939:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22939:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00219", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00219", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13180", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13180", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13365", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13365", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027242912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242912", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LRA9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LRA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LTL9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LTL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J3V5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J3V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3V5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQARALLPTALATLATLAVLALAREPPTAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGRPLDSPCGDSLECVRGVCRCRWTHAVCGTDGHTYADVCALQAASRRALQISGTPVRQLQKGACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIITNAHVVTSSNTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATIVIHPKKKLPMLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQNKHVKGKELTKGADWKKRFIGIRMRTITPSLVEELKAANPDFPSVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEAVLSESPLLLEVRRGNDDLLFSITPEVVV", "length": 467, "header": "tr|A0A9J7J3V5-1|A0A9J7J3V5_CRIGR Isoform 1 of Serine protease HTRA3 OS=Cricetulus griseus OX=10029 GN=Htra3 PE=3 SV=1 CANONICAL=A0A9J7J3V5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LRA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3V5/entry#A0A8C2LRA9-1", "sequence": { "sequence": "MQARALLPTALATLATLAVLALAREPPTAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGRPLDSPCGDSLECVRGVCRCRWTHAVCGTDGHTYADVCALQAASRRALQISGTPVRQLQKGACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIITNAHVVTSSNTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATIVIHPKKKLPMLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQNKHVKALSPALH", "length": 363, "header": "tr|A0A8C2LRA9-1|A0A9J7J3V5_CRIGR Computationally mapped isoform of Serine protease HTRA3 OS=Cricetulus griseus OX=10029 GN=Htra3 PE=3 SV=1 CANONICAL=A0A9J7J3V5-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LTL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3V5/entry#A0A8C2LTL9-1", "sequence": { "sequence": "MQARALLPTALATLATLAVLALAREPPTAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGRPLDSPCGDSLECVRGVCRCRWTHAVCGTDGHTYADVCALQAASRRALQISGTPVRQLQKGACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIITNAHVVTSSNTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATIVIHPKKKLPMLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQNKHVKDWKKRFIGIRMRTITPSLVEELKAANPDFPSVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEAVLSESPLLLEVRRGNDDLLFSITPEVVV", "length": 459, "header": "tr|A0A8C2LTL9-1|A0A9J7J3V5_CRIGR Computationally mapped isoform of Serine protease HTRA3 OS=Cricetulus griseus OX=10029 GN=Htra3 PE=3 SV=1 CANONICAL=A0A9J7J3V5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J3V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3V5/entry#A0A9J7J3V5-1", "sequence": { "sequence": "MQARALLPTALATLATLAVLALAREPPTAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGRPLDSPCGDSLECVRGVCRCRWTHAVCGTDGHTYADVCALQAASRRALQISGTPVRQLQKGACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIITNAHVVTSSNTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATIVIHPKKKLPMLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQNKHVKGKELTKGADWKKRFIGIRMRTITPSLVEELKAANPDFPSVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEAVLSESPLLLEVRRGNDDLLFSITPEVVV", "length": 467, "header": "tr|A0A9J7J3V5-1|A0A9J7J3V5_CRIGR Isoform 1 of Serine protease HTRA3 OS=Cricetulus griseus OX=10029 GN=Htra3 PE=3 SV=1 CANONICAL=A0A9J7J3V5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 28, "start_aa": "Thr", "end_pos": 28, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr28", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRA9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRA9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRA9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRA9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774250", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774250", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J3V5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3V5" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J3V5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3V5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J3V5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3V5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J3V5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3V5" } ], "pmid": "" }, { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J3V5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3V5" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J3V5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3V5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J3V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3V5" }, { "id": "PS51323", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51323" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IGFBP N-terminal", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 90, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7J3V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3V5" }, { "id": "PS51465", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 134, "start_aa": "Gly", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7J3V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3V5" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 354, "end_pos": 440, "start_aa": "His", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 28 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HDF1-1", "uniprot_ac": "A0A9J7HDF1", "uniprot_id": "A0A9J7HDF1_CRIGR", "mass": { "chemical_mass": 109385.0, "monoisotopic_mass": 109385.0 }, "refseq": { "ac": "XP_035307499", "name": "heat shock 70 kDa protein 4L isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307499" }, "gene_names": [ { "name": "Hspa4l", "type": "recommended", "evidence": [ { "id": "A0A9J7HDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF1" } ] }, { "name": "Hspa4l", "type": "synonym", "evidence": [ { "id": "XP_035307499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307499" } ] } ], "protein_names": [ { "name": "Heat shock 70 kDa protein 4L", "type": "recommended", "evidence": [ { "id": "A0A9J7HDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF1/entry#names_and_taxonomy" } ] }, { "name": "Heat shock 70-related protein APG-1", "type": "synonym", "evidence": [ { "id": "A0A9J7HDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF1/entry#names_and_taxonomy" } ] }, { "name": "Osmotic stress protein 94", "type": "synonym", "evidence": [ { "id": "A0A9J7HDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF1/entry#names_and_taxonomy" } ] }, { "name": "heat shock 70 kDa protein 4L isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035307499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307499" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307499", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307499" } ] }, { "annotation": "Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M8M2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M8M2#function" }, { "database": "UniProtKB", "id": "ARBA00054497", "url": "https://www.uniprot.org/uniprotkb/ARBA00054497#function" }, { "database": "UniProtKB", "id": "A0A9J7HDF1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDF1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Hspa4l", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF1", "locus": {} } ], "crossref": [ { "id": "A0A9J7HDF1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HDF1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11738", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11738", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774014", "url": "https://www.ncbi.nlm.nih.gov/gene/100774014", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042708", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042708", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774014", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774014", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WEQSPEI", "url": "https://omabrowser.org/oma/group/WEQSPEI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2M8M2", "url": "https://www.orthodb.org/?gene=A0A8C2M8M2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7HDF1", "url": "https://www.orthodb.org/?gene=A0A9J7HDF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45639", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45639", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45639:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45639:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27508", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27508", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307499", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307499", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M8M2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M8M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M8M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M8M2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDF1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYFAFIIATTAGAIATLAAAAVTAVLIVKGLNTLRDINTDKGTQHADKTSVPSSRIEQEAHKNLDKVDQGLHEEPDTGQQIHEELDPKEVGTKEGPDEKERSSHRDVHGKEQGRQPSSRSAHRGGPQRDAVPAARRGGGMSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNTIHGFKKLHGRSFDDPIVQTERVRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGMLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGIYKQDLPSLDEKPRNVVFIDMGHSAYQVSVCAFNKGKLKVLATTFDPYLGGRNFDEALVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLIAVMDQANLQREDINSIEIVGGATRIPAVKEQVSRFFLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSITLRWKTSFEEGTGECEVFSKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPDPRIGNFTIQNVFPQSDGDSSKVKVKVRINIHGIFSVASASVIEKQNLEGDHNDAPMETETSSKNDNKDDVDKMQVDQEEGGHQKCHAEHTPEEEIDHTGAKTKSPPSDKQDRINQTIKKGKVKSIDLPIQSSLYRQLTQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDKLGTVYEKFITPEDMNKLSAILEDTENWLYEEGEDQPKQVYVDKLQELKKYGQPIQMKYVEHEERPKALNDLGKKIQLVLKVIEAHRNKDERYDHLDPAEMEKVEKYISDSMNWLNSKMNAQNKLSLTQDPVVKVSEIVAKSKELDNFCNSIVYKPKPKVEVPEDKAKANNEHNGPMDGQSGTETNPDPAKGSSQHAESGEMDVD", "length": 978, "header": "tr|A0A9J7HDF1-1|A0A9J7HDF1_CRIGR Isoform 1 of Heat shock 70 kDa protein 4L OS=Cricetulus griseus OX=10029 GN=Hspa4l PE=3 SV=1 CANONICAL=A0A9J7HDF1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M8M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF1/entry#A0A8C2M8M2-1", "sequence": { "sequence": "MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNTIHGFKKLHGRSFDDPIVQTERVRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGMLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGIYKQDLPSLDEKPRNVVFIDMGHSAYQVSVCAFNKGKLKVLATTFDPYLGGRNFDEALVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLIAVMDQANLQREDINSIEIVGGATRIPAVKEQVSRFFLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSITLRWKTSFEEGTGECEVFSKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPDPRIGNFTIQNVFPQSDGDSSKVKVKVRINIHGIFSVASASVIEKQNLEGDHNDAPMETETSSKNDNKDDVDKMQVDQEEGGHQKCHAEHTPEEEIDHTGAKTKSPPSDKQDRINQTIKKGKVKSIDLPIQSSLYRQLTQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDKLGTVYEKFITPEDMNKLSAILEDTENWLYEEGEDQPKQVYVDKLQELKKYGQPIQMKYVEHEERPKALNDLGKKIQLVLKVIEAHRNKDERYDHLDPAEMEKVEKYISDSMNWLNSKMNAQNKLSLTQDPVVKVSEIVAKSKELDNFCNSIVYKPKPKVEVPEDKAKANNEHNGPMDGQSGTETNPDPAKGSSQHAESGEMDVD", "length": 839, "header": "tr|A0A8C2M8M2-1|A0A9J7HDF1_CRIGR Computationally mapped isoform of Heat shock 70 kDa protein 4L OS=Cricetulus griseus OX=10029 GN=Hspa4l PE=3 SV=1 CANONICAL=A0A9J7HDF1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HDF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDF1/entry#A0A9J7HDF1-1", "sequence": { "sequence": "MYFAFIIATTAGAIATLAAAAVTAVLIVKGLNTLRDINTDKGTQHADKTSVPSSRIEQEAHKNLDKVDQGLHEEPDTGQQIHEELDPKEVGTKEGPDEKERSSHRDVHGKEQGRQPSSRSAHRGGPQRDAVPAARRGGGMSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNTIHGFKKLHGRSFDDPIVQTERVRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGMLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGIYKQDLPSLDEKPRNVVFIDMGHSAYQVSVCAFNKGKLKVLATTFDPYLGGRNFDEALVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLIAVMDQANLQREDINSIEIVGGATRIPAVKEQVSRFFLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSITLRWKTSFEEGTGECEVFSKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPDPRIGNFTIQNVFPQSDGDSSKVKVKVRINIHGIFSVASASVIEKQNLEGDHNDAPMETETSSKNDNKDDVDKMQVDQEEGGHQKCHAEHTPEEEIDHTGAKTKSPPSDKQDRINQTIKKGKVKSIDLPIQSSLYRQLTQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDKLGTVYEKFITPEDMNKLSAILEDTENWLYEEGEDQPKQVYVDKLQELKKYGQPIQMKYVEHEERPKALNDLGKKIQLVLKVIEAHRNKDERYDHLDPAEMEKVEKYISDSMNWLNSKMNAQNKLSLTQDPVVKVSEIVAKSKELDNFCNSIVYKPKPKVEVPEDKAKANNEHNGPMDGQSGTETNPDPAKGSSQHAESGEMDVD", "length": 978, "header": "tr|A0A9J7HDF1-1|A0A9J7HDF1_CRIGR Isoform 1 of Heat shock 70 kDa protein 4L OS=Cricetulus griseus OX=10029 GN=Hspa4l PE=3 SV=1 CANONICAL=A0A9J7HDF1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M8M2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M8M2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M8M2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M8M2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774014", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774014", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1NC26-1", "protein_name": "Heat shock 70 kDa protein 4L", "gene_name": "HSPA4L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSVVGIDLGFLNCYIGVARSGGIETIANEYSDRCTPACISLGSKTRAIGNAAKSQIVTNVKNTLHGFKKLHGRAFEDSYIQAERAKLPYELQKMPNGSVGVKVRYLDEERLFAVEQITGMLLAKLKETSESALKKPVADCVISVPSFFTDAERRSVMAAAQIAGLNCLKLMNETTAVALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSICAFNKGKLKVLATTFDPFLGGRNFDEALVDYFSEEFRTKYKLNVKENPRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCAALLSRVEPPLRAAMEQAKLQREDIYSIEIVGGATRIPAVKEQISSFFCKEISTTLNADEAVARGCALQCAILSPAFKVREFSITDVVPYSITLRWKSSYEEGTGECEVFSKNHAAPFSKVITFHKKEPFDLEAFYTHPHEVPYPDSRIGRFTIQNVGPQHDGDNSKVKVKVRVNIHGLFSVANASIIEKQNIDGDHNDAAMDTESSSKNQGREDELDKMQVDQDEGVQKSQAEQQSQADEEAENTGIETKASSGDKQDHPTLPRAKTKVKSIDLPIQASLYRQLGQDLINCYIENEGKMMMQDKLEKERNDAKNAVEEYVYDFRDKLCGVFEKFITEEDTNKLTLMLEDTENWLYEDGEDQPKQVYMDKLQELRKFGQPIQERYMEHEERPKVLNELGKKIQLLMKAVEAYKNKDEKYDHLDPAEMEKVEKYISEAMNWLNTKMNAQNKLSLTQDPVVKVAEIISKSKELDSFCNPIIYKPKPKIEPPNDGQSKANGEHNGPVNGQSSTETGPDPAKDNSQQTKPSGEMEVD", "length": 843 }, "evidence": [ { "id": "A0A9J7HDF1", "url": "https://omabrowser.org/oma/group/A0A9J7HDF1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "M9MSL3-1", "protein_name": "Heat shock protein 110, isoform G", "gene_name": "Hsp110", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSVIGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVGGFKRLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSAAAMQTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRNVIFVDFGHSSLQASACAFTKGKLKMLASTWDQIGGRDIDLALGDYFAKEFQERYKINAKTNARANLRLLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLAESKLQLDDIHSVEIVGGSSRIPSVKQLIEQVFNKPASTTLNQDEAVSRGAALQCAIMSPAVRVREFGVTDIQNYAVKVLWDSEGSAAPGEIEIFPQYHASPFSRLLTINRKGPFNVSIVYGQQVPYPDQTIGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKKEAEEAAAAAEQAASEEKPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGSGADKKKKASKATELPLECTTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRNKLQGGPFERYVVEAEREKIVSQLNDLENWLYEDGEDCERDIYTSRLQALHQKTDPIKLRASDYEQGPAAFDELKNSIAIARLAVAEFRKGVPKYDHLTETEFINISETADKAQSWLDANLPKFTQSPRTADSPVQISAVRQEVQTLNSCVSSVINRAKPKPTPAKTATPPKDEANAEQNGGEPAANSGDKMDVDNNGQSAAGNDPSMEVE", "length": 836 }, "evidence": [ { "id": "A0A9J7HDF1", "url": "https://omabrowser.org/oma/group/A0A9J7HDF1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P32589-1", "protein_name": "Heat shock protein homolog SSE1", "gene_name": "SSE1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTPFGLDLGNNNSVLAVARNRGIDIVVNEVSNRSTPSVVGFGPKNRYLGETGKNKQTSNIKNTVANLKRIIGLDYHHPDFEQESKHFTSKLVELDDKKTGAEVRFAGEKHVFSATQLAAMFIDKVKDTVKQDTKANITDVCIAVPPWYTEEQRYNIADAARIAGLNPVRIVNDVTAAGVSYGIFKTDLPEGEEKPRIVAFVDIGHSSYTCSIMAFKKGQLKVLGTACDKHFGGRDFDLAITEHFADEFKTKYKIDIRENPKAYNRILTAAEKLKKVLSANTNAPFSVESVMNDVDVSSQLSREELEELVKPLLERVTEPVTKALAQAKLSAEEVDFVEIIGGTTRIPTLKQSISEAFGKPLSTTLNQDEAIAKGAAFICAIHSPTLRVRPFKFEDIHPYSVSYSWDKQVEDEDHMEVFPAGSSFPSTKLITLNRTGDFSMAASYTDITQLPPNTPEQIANWEITGVQLPEGQDSVPVKLKLRCDPSGLHTIEEAYTIEDIEVEEPIPLPEDAPEDAEQEFKKVTKTVKKDDLTIVAHTFGLDAKKLNELIEKENEMLAQDKLVAETEDRKNTLEEYIYTLRGKLEEEYAPFASDAEKTKLQGMLNKAEEWLYDEGFDSIKAKYIAKYEELASLGNIIRGRYLAKEEEKKQAIRSKQEASQMAAMAEKLAAQRKAEAEKKEEKKDTEGDVDMD", "length": 693 }, "evidence": [ { "id": "A0A9J7HDF1", "url": "https://omabrowser.org/oma/group/A0A9J7HDF1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P48722-1", "protein_name": "Heat shock 70 kDa protein 4L", "gene_name": "Hspa4l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSTGVKVRYLEEERPFAIEQVTGMLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGIYKQDLPSLDEKPRNVVFIDMGHSAYQVSVCAFNKGKLKVLATTFDPYLGGRNFDEALVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLKSVMDQANLQREDINSIEIVGGATRIPAVKEQVTRFFLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSVTLRWKTSFEEGTGECEVFSKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPDPRIGNFTIQNVFPQSDGDSSKVKVKVRINIHGIFSVASASVIEKQNLEGDHNDAAMETEAPKSEGKEDVDKMQVDQEEGGHQKCHAEHTPEEEIDHTGAKAKAPPSDKQDRINQTIKKGKIKSIDLPIQSSLYRQLTQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDKLGTVYEKFITPEDMNKLSAMLEDTENWLYEEGEDQPKQVYVDRLQELKKYGQPIQMKYVEHEERPKALNDLGKKIQLVLKVIEAHRNKDERYDHLDPAEMERVEKYISDSMNWLNSKMNAQNKLSLTQDPVVKVSEIVTKSKELDNFCNPIVYKPKPKVEAPEDKAKTGSEHNGPMDGQSGSETSPDPPKGSSQHTDSGEMEVD", "length": 838 }, "evidence": [ { "id": "A0A9J7HDF1", "url": "https://omabrowser.org/oma/group/A0A9J7HDF1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P83581-1", "protein_name": "Heat shock 70 kDa protein 4L", "gene_name": "Hspa4l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSAMLEDTENWLYEELSLTQDPVV", "length": 24 }, "evidence": [ { "id": "A0A9J7HDF1", "url": "https://omabrowser.org/oma/group/A0A9J7HDF1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6TMK3-1", "protein_name": "Heat shock protein 88", "gene_name": "hspH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSFVVGFDFGTKNCTIAVAQKGGVDVIANEVSNRLTPSMVSFGEKERYLGESALTNQLRNIRNTITNIKRFIGQEFKTDTVQEELKHEMFQSYEMDNGFVGYNVTYAGEQCSFSSEAILGMLFGKLKKTTEAFVNNPVRDVVISVPVFWNDYQRRAILNAGSIAGLNIIRLINETTATALSYGIYKEWSETDPTNVLFVDVGDSATSVSAVQYKKGQLKVLGTASNPNIGSRVFDETLVKHFAKEFQTKYKINVFENKKALIRLRQACEKVKKILSSNNEAPVSIDSLMDDKDVKGMIDRATFEELANDDMNTIVEPLQRLLSELQMTPDQFQSIEITGGGTRSTSLQKKLSEVLGRDLSKTINSEESVCRGAALQCAMLSPVFRVRPFAVNDVASYPVSVHFKSVSGVEQKLDLFNLKSAIPTPKPLRISFPVTKAEGFEIVVNSTFGTIATVKVDNIPAFTNKSSIKAKVWLDIHGIFHIDEVKLVEQIPEEETAAPAETPAETPANGEAAKPAEEKKVKVKETSLVFTTSRKGLTNELLKAAIEEEGRMQASDLLAIETAEKKNALESYIYDMRSKLQSSLKEYVTPADAETFMTQLNKQMDWLESEEGEDQTKSVYAGKLEELRRLGNPIQKRKQDLEDYPDAVQTLKNIASYVKNEAMIPGERYDHIEKEEKEKLCKDCDDAVEWIDALVAKQQATPKTQPCIINTTEVLAKKTQLEVTAKMILGKPKPKPVEVPKEEPKDTPMESKDAPAEEPVATKDQKMDDILD", "length": 772 }, "evidence": [ { "id": "A0A9J7HDF1", "url": "https://omabrowser.org/oma/group/A0A9J7HDF1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "X1WBR5-1", "protein_name": "Heat shock 70 kDa protein 4L", "gene_name": "hspa4l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVVGIDVGFQNCYIAVARSGGIETIANEYSDRCTPACISLASKNRTIGNAAKSQIITNFKNTVHGFKKFHGRAFDDPFVQGEKSRLPYSLHKLDNGNAGIKVRYLNEDKVFTIEQVTAMLLTKLKETSEHALKKPVVDCVISVPSFFTDVERRSVMDATQIAGLNCLRLINDTTAVALAYGIYKQDLPNPEEKPRNVVFVDIGHSSYQVAIASFNKGKLKMLATAFDPYLGGRNFDEILVEYFCEDFKNRFKLNVKDNPRALLRLYQECEKLKKLMSANSSDLPLNIECFMNDIDVHGKLNRTQFEEMCSQLMMRVEAPLRSVMEQSKLSRDEIYAIEVVGGATRMPAIKERISKFFGKDTSTTLNADEAVARGSALQCAILSPAFKVREFSITDTVPFPITLRWKSPTDESVGECEVYSKNHPAPFSKIITFHKKEPFDLEAFYSCPHDLPYPDVRIGRFSVQNVVPQPDGDSSKVKVKVRVNVHGIFSVSSASLIEKQKGEPEDVQMDTEPTVQNEGRPEEQSKMQVDQEGQGEQPSEEERANNSGIKDGDKQDQGASSSKAKSKVKSVDLPILANTTRQLDRDVLTHFVEYEKKMIIQDKLEKERNDAKNGVEEYVYDLRDKLCGIYEKYVTEDESNRLTIMLEDTENWLYEEGEDQDKEIYQHKLAELKKYGEPIEERYREHEGRPRAFDELGKKLQLFMKVVDMYRDKDERYEHLSAEDMGVVEKSVNEALGWMNTKMNAQSKLSFAQDPAVKVADIIQKIQELEDVCNPILNRPKPKTEELVEEGDKSDGAHNGPTAQQGADSKGNQQTKPPSGEMDVD", "length": 826 }, "evidence": [ { "id": "A0A9J7HDF1", "url": "https://omabrowser.org/oma/group/A0A9J7HDF1/", "database": "OMA" } ], "glygen_name": "Zebrafish", 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:: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027252886", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252886" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J795", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J795" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Klf7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J795", "locus": {} } ], "crossref": [ { "id": "cd21585", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21585", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755667", "url": "https://www.ncbi.nlm.nih.gov/gene/100755667", "database": "GeneID", "categories": [ "Genome 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"https://www.uniprot.org/uniprotkb/A0A9J7J795" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J795", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J795" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J795", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J795" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J795", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J795" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J795", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J795" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J795" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 218, "end_pos": 247, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 188 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HCC5-1", "uniprot_ac": "A0A9J7HCC5", "uniprot_id": "A0A9J7HCC5_CRIGR", "mass": { "chemical_mass": 320634.0, "monoisotopic_mass": 320634.0 }, "refseq": { "ac": "XP_035306847", "name": "centrosomal protein of 290 kDa isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306847" }, "gene_names": [ { "name": "Cep290", "type": "recommended", "evidence": [ { "id": "A0A9J7HCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5" } ] }, { "name": "Cep290", "type": "synonym", "evidence": [ { "id": "XP_035306847", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306847" } ] } ], "protein_names": [ { "name": "Centrosomal protein of 290 kDa isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7HCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5/entry#names_and_taxonomy" } ] }, { "name": "centrosomal protein of 290 kDa isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035306847", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306847" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306847", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306847" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cep290", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5", "locus": {} } ], "crossref": [ { "id": "100753037", "url": "https://www.ncbi.nlm.nih.gov/gene/100753037", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753037", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753037", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MQZ6", "url": "https://www.orthodb.org/?gene=A0A8C2MQZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7HCC5", "url": "https://www.orthodb.org/?gene=A0A9J7HCC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18879", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18879", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18879:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18879:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16574", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16574", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306847", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306847", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MQZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MQZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA51", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HA51-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K2Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPSINWKELIKVDPDDLPRQEELADNLLISLSKVEVNELKDEDQENVVHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLLSRRGEDSDYRSQLSKKNFELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAVVHQTDTVMDQIKKENEHYRLQVQELSDLLKAKDEEDDPVMIAVNAKVEEWKLILSSKDDEIIEYQQMLHSLREKLKNAQLDADKSNIMALKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELKKDKGTSNFHHQTHYMKIHSKVQILEEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVIEIKNCKAQIKIRDGEIEVLTKEINKLEMKINDVLDENEALRERAGLEPKTMIDLTEFRNSKRLKQQQYRAENQILLKEIESLEEERLDLKRKIRQMAQERGKRNAASGLTTEDLSLTENFSWEDKMGERNLSFMSLKSMNETQSKIKSPAKIELLHRRPSFSIRQSDQNKTEENMTVQSLSRMLSGTHRSVESGVDPIVSLTRWSSFVQVKDDTTTPEAITIREIFKAPCLQSLRNQDSLVSTFSKGSNEEIRDYLCSLSDECMKKVSGSCQALEKTRLLQKSSSSSQASPTASEQMQKLSHRQKSAVFSHQSYDHDIDKVTSADEQVHSQIKNADKRQSESPSQTEMMRSAIEANLSDPVPVAAQPKLSHIDPLENLIEQLQRELVFLRSQNENIAQDLSIQEDQSRNAEIELDRQRSQAEQNEFLSRELIEKERDLERSRTIIAKFQNKLKELVEENKQLEEGMKEILQAIKDMQRDPDVKGCETSLIIPSLERLVNAMESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLVKANLKIDHLEKETDLLRQSSGSNVVYKGADLPDGIAPSSAHIINSQNEYLIHLLQELDNKEKKLKHVEESLEDYNRKFAVIRHQQSLLYKEYLSEKETWKTESETMKEEKRKLEDQVSQDAVKVKEYNNLLNALQRDSNEMKKMLSENSRKITVLQVNEKSLIRKYTTLVELERQLRKENGKHKNDLISMEAEVTEKIGSLQRYKEMATFKIAALQKVVDNSVSLSELDLANKQYNELTTKYRDILQKDNMLVQRASNLEHLECENASLKEQMDVISKELEITKEKLHTIEQAWEQETKLGTESNMDKAMKSITNSDIVSISKKITVLEMKELNERQRAEHCQKMYEHVRTSLKQMEERNFELETKFTELTKINLDAQKVEQMLRDELADSVNKAVSDADRQRILELEKNEVELKVEVSKLREISDIAKRQVDFLNSQQQSREKEVESLRMQLLDYQAQSDEKALIAKLHQHVVSLQISEATALGKLESVTSKLQKMEAYNLRLEQKLDEKEQTLFYARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQERRNMENKTMEMELKLKGLEELISTLKDARGAQKVINWHVKIEELRLQELKLNRELAKGKEEIKYLNNIISEYEQTINSLEEEIVQQSKFHEERQMAWDQREVELERQLDLFDRQQNEILSAAQKFEEATGSMPDPSLPLPNQLEIALHKIKENIRTILKTQATCKSLEEKLKEKESALQLAEQNILSRDKVINELRIRLPATADREKLIAELDRKELEPKSHHTMKIAHQTIANMQARLNQKEEVLKKYQHLLEKAREEQREIVKKHEEDLHALHHKLELQADSSLNKFKQTAQDLIKQSPVPVPTNKHFIRLAEMEQTVAEQDNSLASLLTKLKKVSKDLESQKEITELKVREFENMKLRLQENHLGEMKKVKVEVEDLRRALLQAQKESQGLKSELQAQKEANSRAPTTTMRNLVDRLKSQLALKEKQQKALSRALLELRAEMTAAAEERIIAVTSQKEANLNVQQVVDRHTRELKSQIEDLNENLLKLKEALKTSKNKENSLVDDLNDLSNELQKKQKAFNKILREKDGIDQENEELRRQIKRLSSGLQSKSLLDNKQSLIDELQKKVKKLESQLERKVDDIDIKPVKEKSAREELIRWEEGKKWQTKVEGMRNKLKEKEGEVHSLTKQLHTLKELFAKADKEKLTLQKKLKTTGMTVDQVLGVRALESEKELEELKKRNLDLENDILYMRTHQALPRDSVVEDLHLQNKYLQEKLRTLEKQLSKDAYPQSLTSEIESDDHCQKEQELLRENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKGKMEVERKLGQVRGSGRSGKTVPELEKTIGLMKKVVEKVQKENEQLQKASGILTSEKMANIEEENENLKVELEKLKAHFGRQLSMEYESKNKGTMRVIVENERLRKELKKEMETSENLRIAKNNLELVNDKMVLQLEETSKRLQFAESRGPQLEGADSKSWKSIVVTRMYETKMKELESDISKKNQSIVDLKQLVREATEREQKAKKYTEDLEQQIEILKNVSEGVETDQELIQELQLLRLANSKLDKEKAELIHQIKANKDQTGAESSTPDPDQLKEKVNDLETQLRKSDLDKQHLKEEIKKLKKELQNFDPSFFEEIEDLKYNYKKEVKKNILLEQKLKKLSEQFGFELPSPVAASEDGESPGESPNNFPIY", "length": 2751, "header": "tr|A0A9J7HCC5-1|A0A9J7HCC5_CRIGR Isoform 1 of Centrosomal protein of 290 kDa isoform X1 OS=Cricetulus griseus OX=10029 GN=Cep290 PE=4 SV=1 CANONICAL=A0A9J7HCC5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MQZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5/entry#A0A8C2MQZ6-1", "sequence": { "sequence": "MPPSINWKELIKVDPDDLPRQEELADNLLISLSKVEVNELKDEDQENVVHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLLSRRGEDSDYRSQLSKKNFELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAVVHQTDTVMDQIKKENEHYRLQVQELSDLLKAKDEEDDPVMIAVNAKVEEWKLILSSKDDEIIEYQQMLHSLREKLKNAQLDADKSNIMALKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELKKDKGTSNFHHQTHYMKIHSKVQILEEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVIEIKNCKAQIKIRDGEIEVLTKEINKLEMKINDVLDENEALRERAGLEPKTMIDLTEFRNSKRLKQQQYRAENQILLKEIESLEEERLDLKRKIRQMAQERGKRNAASGLTTEDLSLTENFSWEDKMGERNLSFMSLKSMNETQSKNEFLSRELIEKERDLERSRTIIAKFQNKLKELVEENKQLEEGMKEILQAIKDMQRDPDVKGCETSLIIPSLERLVNAMESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLVKANLKIDHLEKETDLLRQSSGSNVVYKGADLPDGIAPSSAHIINSQNEYLIHLLQELDNKEKKLKHVEESLEDYNRKFAVIRHQQSLLYKEYLSEKETWKTESETMKEEKRKLEDQVSQDAVKVKEYNNLLNALQRDSNEMKKMLSENSRKITVLQVNEKSLIRKYTTLVELERQLRKENGKHKNDLISMEAEVTEKIGSLQRYKEMATFKIAALQKVVDNSVSLSELDLANKQYNELTTKYRDILQKDNMLVQRASNLEHLECENASLKEQMDVISKELEITKEKLHTIEQAWEQETKLGTESNMDKAMKSITNSDIVSISKKITVLEMKELNERQRAEHCQKMYEHVRTSLKQMEERNFELETKFTELTKINLDAQKVEQMLRDELADSVNKAVSDADRQRILELEKNEVELKVEVSKLREISDIAKRQVDFLNSQQQSREKEVESLRMQLLDYQAQSDEKALIAKLHQHVVSLQISEATALGKLESVTSKLQKMEAYNLRLEQKLDEKEQTLFYARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQERRNMENKTMEMELKLKGLEELISTLKDARGAQKVINWHVKIEELRLQELKLNRELAKGKEEIKYLNNIISEYEQTINSLEEEIVQQSKFHEERQMAWDQREVELERQLDLFDRQQNEILSAAQKFEEATGSMPDPSLPLPNQLEIALHKIKENIRTILKTQATCKSLEEKLKEKESALQLAEQNILSRDKVINELRIRLPATADREKLIAELDRKELEPKSHHTMKIAHQTIANMQARLNQKEEVLKKYQHLLEKAREEQREIVKKHEEDLHALHHKLELQADSSLNKFKQTAQDLIKQSPVPVPTNKHFIRLAEMEQTVAEQDNSLASLLTKLKKVSKDLESQKEITELKVREFENMKLRLQENHLGEMKKVKVEVEDLRRALLQAQKESQGLKSELQAQKEANSRAPTTTMRNLVDRLKSQLALKEKQQKALSRALLELRAEMTAAAEERIIAVTSQKEANLNVQQVVDRHTRELKSQIEDLNENLLKLKEALKTSKNKENSLVDDLNDLSNELQKKQKAFNKILREKDGIDQENEELRRQIKRLSSGLQSKSLLDNKQSLIDELQKKVKKLESQLERKVDDIDIKPVKEKSAREELIRWEEGKKWQTKVEGMRNKLKEKEGEVHSLTKQLHTLKELFAKADKEKLTLQKKLKTTGMTVDQVLGVRALESEKELEELKKRNLDLENDILYMRTHQALPRDSVVEDLHLQNKYLQEKLRTLEKQLSKDAYPQSLTSEIESDDHCQKEQELLRENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKGKMEVERKLGQVRGSGRSGKTVPELEKTIGLMKKVVEKVQKENEQLQKASGILTSEKMANIEEENENLKVELEKLKAHFGRQLSMEYESKNKGTMRVIVENERLRKELKKEMETSENLRIAKNNLELVNDKMVLQLEETSKRLQFAESRGPQLEGADSKSWKSIVVTRMYETKMKELESDISKKNQSIVDLKQLVREATEREQKAKKYTEDLEQQIEILKNVSEGVETDQELIQELQLLRLANSKLDKEKAELIHQIKANKDQTGAESSTPDPDQLKEKVNDLETQLRKSDLDKQHLKEEIKKLKKELQNFDPSFFEEIEDLKYNYKKEVKKNILLEQKLKKLSEQFGFELPSPVAASEDGESPGESPNNFPIY", "length": 2473, "header": "tr|A0A8C2MQZ6-1|A0A9J7HCC5_CRIGR Computationally mapped isoform of Centrosomal protein of 290 kDa isoform X1 OS=Cricetulus griseus OX=10029 GN=Cep290 PE=4 SV=1 CANONICAL=A0A9J7HCC5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HA51-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5/entry#A0A9J7HA51-1", "sequence": { "sequence": "MNNEKGYVLALYIRMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLLSRRGEDSDYRSQLSKKNFELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAVVHQTDTVMDQIKKENEHYRLQVQELSDLLKAKDEEDDPVMIAVNAKVEEWKLILSSKDDEIIEYQQMLHSLREKLKNAQLDADKSNIMALKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELKKDKGTSNFHHQTHYMKIHSKVQILEEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVIEIKNCKAQIKIRDGEIEVLTKEINKLEMKINDVLDENEALRERAGLEPKTMIDLTEFRNSKRLKQQQYRAENQILLKEIESLEEERLDLKRKIRQMAQERGKRNAASGLTTEDLSLTENFSWEDKMGERNLSFMSLKSMNETQSKIKSPAKIELLHRRPSFSIRQSDQNKTEENMTVQSLSRMLSGTHRSVESGVDPIVSLTRWSSFVQVKDDTTTPEAITIREIFKAPCLQSLRNQDSLVSTFSKGSNEEIRDYLCSLSDECMKKVSGSCQALEKTRLLQKSSSSSQASPTASEQMQKLSHRQKSAVFSHQSYDHDIDKVTSADEQVHSQIKNADKRQSESPSQTEMMRSAIEANLSDPVPVAAQPKLSHIDPLENLIEQLQRELVFLRSQNENIAQDLSIQEDQSRNAEIELDRQRSQAEQNEFLSRELIEKERDLERSRTIIAKFQNKLKELVEENKQLEEGMKEILQAIKDMQRDPDVKGCETSLIIPSLERLVNAMESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLVKANLKIDHLEKETDLLRQSSGSNVVYKGADLPDGIAPSSAHIINSQNEYLIHLLQELDNKEKKLKHVEESLEDYNRKFAVIRHQQSLLYKEYLSEKETWKTESETMKEEKRKLEDQVSQDAVKVKEYNNLLNALQRDSNEMKKMLSENSRKITVLQVNEKSLIRKYTTLVELERQLRKENGKHKNDLISMEAEVTEKIGSLQRYKEMATFKIAALQKVVDNSVSLSELDLANKQYNELTTKYRDILQKDNMLVQRASNLEHLECENASLKEQMDVISKELEITKEKLHTIEQAWEQETKLGTESNMDKAMKSITNSDIVSISKKITVLEMKELNERQRAEHCQKMYEHVRTSLKQMEERNFELETKFTELTKINLDAQKVEQMLRDELADSVNKAVSDADRQRILELEKNEVELKVEVSKLREISDIAKRQVDFLNSQQQSREKEVESLRMQLLDYQAQSDEKALIAKLHQHVVSLQISEATALGKLESVTSKLQKMEAYNLRLEQKLDEKEQTLFYARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQERRNMENKTMEMELKLKGLEELISTLKDARGAQKVINWHVKIEELRLQELKLNRELAKGKEEIKYLNNIISEYEQTINSLEEEIVQQSKFHEERQMAWDQREVELERQLDLFDRQQNEILSAAQKFEEATGSMPDPSLPLPNQLEIALHKIKENIRTILKTQATCKSLEEKLKEKESALQLAEQNILSRDKVINELRIRLPATADREKLIAELDRKELEPKSHHTMKIAHQTIANMQARLNQKEEVLKKYQHLLEKAREEQREIVKKHEEDLHALHHKLELQADSSLNKFKQTAQDLIKQSPVPVPTNKHFIRLAEMEQTVAEQDNSLASLLTKLKKVSKDLESQKEITELKVREFENMKLRLQENHLGEMKKVKVEVEDLRRALLQAQKESQGLKSELQAQKEANSRAPTTTMRNLVDRLKSQLALKEKQQKALSRALLELRAEMTAAAEERIIAVTSQKEANLNVQQVVDRHTRELKSQIEDLNENLLKLKEALKTSKNKENSLVDDLNDLSNELQKKQKAFNKILREKDGIDQENEELRRQIKRLSSGLQSKSLLDNKQSLIDELQKKVKKLESQLERKVDDIDIKPVKEKSAREELIRWEEGKKWQTKVEGMRNKLKEKEGEVHSLTKQLHTLKELFAKADKEKLTLQKKLKTTGMTVDQVLGVRALESEKELEELKKRNLDLENDILYMRTHQALPRDSVVEDLHLQNKYLQEKLRTLEKQLSKDAYPQSLTSEIESDDHCQKEQELLRENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKGKMEVERKLGQVRGSGRSGKTVPELEKTIGLMKKVVEKVQKENEQLQKASGILTSEKMANIEEENENLKVELEKLKAHFGRQLSMEYESKNKGTMRVIVENERLRKELKKEMETSENLRIAKNNLELVNDKMVLQLEETSKRLQFAESRGPQLEGADSKSWKSIVVTRMYETKMKELESDISKKNQSIVDLKQLVREATEREQKAKKYTEDLEQQIEILKNVSEGVETDQELIQELQLLRLANSKLDKEKAELIHQIKANKDQTGAESSTPDPDQLKEKVNDLETQLRKSDLDKQHLKEEIKKLKKELQNFDPSFFEEIEDLKYNYKKEVKKNILLEQKLKKLSEQFGFELPSPVAASEDGESPGESPNNFPIY", "length": 2705, "header": "tr|A0A9J7HA51-1|A0A9J7HCC5_CRIGR Computationally mapped isoform of Centrosomal protein of 290 kDa isoform X1 OS=Cricetulus griseus OX=10029 GN=Cep290 PE=4 SV=1 CANONICAL=A0A9J7HCC5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HCC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5/entry#A0A9J7HCC5-1", "sequence": { "sequence": "MPPSINWKELIKVDPDDLPRQEELADNLLISLSKVEVNELKDEDQENVVHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLLSRRGEDSDYRSQLSKKNFELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAVVHQTDTVMDQIKKENEHYRLQVQELSDLLKAKDEEDDPVMIAVNAKVEEWKLILSSKDDEIIEYQQMLHSLREKLKNAQLDADKSNIMALKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELKKDKGTSNFHHQTHYMKIHSKVQILEEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVIEIKNCKAQIKIRDGEIEVLTKEINKLEMKINDVLDENEALRERAGLEPKTMIDLTEFRNSKRLKQQQYRAENQILLKEIESLEEERLDLKRKIRQMAQERGKRNAASGLTTEDLSLTENFSWEDKMGERNLSFMSLKSMNETQSKIKSPAKIELLHRRPSFSIRQSDQNKTEENMTVQSLSRMLSGTHRSVESGVDPIVSLTRWSSFVQVKDDTTTPEAITIREIFKAPCLQSLRNQDSLVSTFSKGSNEEIRDYLCSLSDECMKKVSGSCQALEKTRLLQKSSSSSQASPTASEQMQKLSHRQKSAVFSHQSYDHDIDKVTSADEQVHSQIKNADKRQSESPSQTEMMRSAIEANLSDPVPVAAQPKLSHIDPLENLIEQLQRELVFLRSQNENIAQDLSIQEDQSRNAEIELDRQRSQAEQNEFLSRELIEKERDLERSRTIIAKFQNKLKELVEENKQLEEGMKEILQAIKDMQRDPDVKGCETSLIIPSLERLVNAMESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLVKANLKIDHLEKETDLLRQSSGSNVVYKGADLPDGIAPSSAHIINSQNEYLIHLLQELDNKEKKLKHVEESLEDYNRKFAVIRHQQSLLYKEYLSEKETWKTESETMKEEKRKLEDQVSQDAVKVKEYNNLLNALQRDSNEMKKMLSENSRKITVLQVNEKSLIRKYTTLVELERQLRKENGKHKNDLISMEAEVTEKIGSLQRYKEMATFKIAALQKVVDNSVSLSELDLANKQYNELTTKYRDILQKDNMLVQRASNLEHLECENASLKEQMDVISKELEITKEKLHTIEQAWEQETKLGTESNMDKAMKSITNSDIVSISKKITVLEMKELNERQRAEHCQKMYEHVRTSLKQMEERNFELETKFTELTKINLDAQKVEQMLRDELADSVNKAVSDADRQRILELEKNEVELKVEVSKLREISDIAKRQVDFLNSQQQSREKEVESLRMQLLDYQAQSDEKALIAKLHQHVVSLQISEATALGKLESVTSKLQKMEAYNLRLEQKLDEKEQTLFYARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQERRNMENKTMEMELKLKGLEELISTLKDARGAQKVINWHVKIEELRLQELKLNRELAKGKEEIKYLNNIISEYEQTINSLEEEIVQQSKFHEERQMAWDQREVELERQLDLFDRQQNEILSAAQKFEEATGSMPDPSLPLPNQLEIALHKIKENIRTILKTQATCKSLEEKLKEKESALQLAEQNILSRDKVINELRIRLPATADREKLIAELDRKELEPKSHHTMKIAHQTIANMQARLNQKEEVLKKYQHLLEKAREEQREIVKKHEEDLHALHHKLELQADSSLNKFKQTAQDLIKQSPVPVPTNKHFIRLAEMEQTVAEQDNSLASLLTKLKKVSKDLESQKEITELKVREFENMKLRLQENHLGEMKKVKVEVEDLRRALLQAQKESQGLKSELQAQKEANSRAPTTTMRNLVDRLKSQLALKEKQQKALSRALLELRAEMTAAAEERIIAVTSQKEANLNVQQVVDRHTRELKSQIEDLNENLLKLKEALKTSKNKENSLVDDLNDLSNELQKKQKAFNKILREKDGIDQENEELRRQIKRLSSGLQSKSLLDNKQSLIDELQKKVKKLESQLERKVDDIDIKPVKEKSAREELIRWEEGKKWQTKVEGMRNKLKEKEGEVHSLTKQLHTLKELFAKADKEKLTLQKKLKTTGMTVDQVLGVRALESEKELEELKKRNLDLENDILYMRTHQALPRDSVVEDLHLQNKYLQEKLRTLEKQLSKDAYPQSLTSEIESDDHCQKEQELLRENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKGKMEVERKLGQVRGSGRSGKTVPELEKTIGLMKKVVEKVQKENEQLQKASGILTSEKMANIEEENENLKVELEKLKAHFGRQLSMEYESKNKGTMRVIVENERLRKELKKEMETSENLRIAKNNLELVNDKMVLQLEETSKRLQFAESRGPQLEGADSKSWKSIVVTRMYETKMKELESDISKKNQSIVDLKQLVREATEREQKAKKYTEDLEQQIEILKNVSEGVETDQELIQELQLLRLANSKLDKEKAELIHQIKANKDQTGAESSTPDPDQLKEKVNDLETQLRKSDLDKQHLKEEIKKLKKELQNFDPSFFEEIEDLKYNYKKEVKKNILLEQKLKKLSEQFGFELPSPVAASEDGESPGESPNNFPIY", "length": 2751, "header": "tr|A0A9J7HCC5-1|A0A9J7HCC5_CRIGR Isoform 1 of Centrosomal protein of 290 kDa isoform X1 OS=Cricetulus griseus OX=10029 GN=Cep290 PE=4 SV=1 CANONICAL=A0A9J7HCC5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K2Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5/entry#A0A9J7K2Y2-1", "sequence": { "sequence": "MPPSINWKELIKVDPDDLPRQEELADNLLISLSKVEVNELKDEDQENVVHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRDEIRQLEKQLEQKDRELEDMEKELDKEKKVNEQLALRNEEAENENSKLRRENEQLRQDIIDYQKQIDSQKESLLSRRGEDSDYRSQLSKKNFELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAVVHQTDTVMDQIKKENEHYRLQVQELSDLLKAKDEEDDPVMIAVNAKVEEWKLILSSKDDEIIEYQQMLHSLREKLKNAQLDADKSNIMALKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELKKDKGTSNFHHQTHYMKIHSKVQILEEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVIEIKNCKAQIKIRDGEIEVLTKEINKLEMKINDVLDENEALRERAGLEPKTMIDLTEFRNSKRLKQQQYRAENQILLKEIESLEEERLDLKRKIRQMAQERGKRNAASGLTTEDLSLTENFSWEDKMGERNLSFMSLKSMNETQSKNENIAQDLSIQEDQSRNAEIELDRQRSQAEQNEFLSRELIEKERDLERSRTIIAKFQNKLKELVEENKQLEEGMKEILQAIKDMQRDPDVKGCETSLIIPSLERLVNAMESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLVKANLKIDHLEKETDLLRQSSGSNVVYKGADLPDGIAPSSAHIINSQNEYLIHLLQELDNKEKKLKHVEESLEDYNRKFAVIRHQQSLLYKEYLSEKETWKTESETMKEEKRKLEDQVSQDAVKVKEYNNLLNALQRDSNEMKKMLSENSRKITVLQVNEKSLIRKYTTLVELERQLRKENGKHKNDLISMEAEVTEKIGSLQRYKEMATFKIAALQKVVDNSVSLSELDLANKQYNELTTKYRDILQKDNMLVQRASNLEHLECENASLKEQMDVISKELEITKEKLHTIEQAWEQETKLGTESNMDKAMKSITNSDIVSISKKITVLEMKELNERQRAEHCQKMYEHVRTSLKQMEERNFELETKFTELTKINLDAQKVEQMLRDELADSVNKAVSDADRQRILELEKNEVELKVEVSKLREISDIAKRQVDFLNSQQQSREKEVESLRMQLLDYQAQSDEKALIAKLHQHVVSLQISEATALGKLESVTSKLQKMEAYNLRLEQKLDEKEQTLFYARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQERRNMENKTMEMELKLKGLEELISTLKDARGAQKVINWHVKIEELRLQELKLNRELAKGKEEIKYLNNIISEYEQTINSLEEEIVQQSKFHEERQMAWDQREVELERQLDLFDRQQNEILSAAQKFEEATGSMPDPSLPLPNQLEIALHKIKENIRTILKTQATCKSLEEKLKEKESALQLAEQNILSRDKVINELRIRLPATADREKLIAELDRKELEPKSHHTMKIAHQTIANMQARLNQKEEVLKKYQHLLEKAREEQREIVKKHEEDLHALHHKLELQADSSLNKFKQTAQDLIKQSPVPVPTNKHFIRLAEMEQTVAEQDNSLASLLTKLKKVSKDLESQKEITELKVREFENMKLRLQENHLGEMKKVKVEVEDLRRALLQAQKESQGLKSELQAQKEANSRAPTTTMRNLVDRLKSQLALKEKQQKALSRALLELRAEMTAAAEERIIAVTSQKEANLNVQQVVDRHTRELKSQIEDLNENLLKLKEALKTSKNKENSLVDDLNDLSNELQKKQKAFNKILREKDGIDQENEELRRQIKRLSSGLQSKSLLDNKQSLIDELQKKVKKLESQLERKVDDIDIKPVKEKSAREELIRWEEGKKWQTKVEGMRNKLKEKEGEVHSLTKQLHTLKELFAKADKEKLTLQKKLKTTGMTVDQVLGVRALESEKELEELKKRNLDLENDILYMRTHQALPRDSVVEDLHLQNKYLQEKLRTLEKQLSKDAYPQSLTSEIESDDHCQKEQELLRENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKGKMEVERKLGQVRGSGRSGKTVPELEKTIGLMKKVVEKVQKENEQLQKASGILTSEKMANIEEENENLKVELEKLKAHFGRQLSMEYESKNKGTMRVIVENERLRKELKKEMETSENLRIAKNNLELVNDKMVLQLEETSKRLQFAESRGPQLEGADSKSWKSIVVTRMYETKMKELESDISKKNQSIVDLKQLVREATEREQKAKKYTEDLEQQIEILKNVSEGVETDQELIQELQLLRLANSKLDKEKAELIHQIKANKDQTGAESSTPDPDQLKEKVNDLETQLRKSDLDKQHLKEEIKKLKKELQNFDPSFFEEIEDLKYNYKKEVKKNILLEQKLKKLSEQFGFELPSPVAASEDGESPGESPNNFPIY", "length": 2504, "header": "tr|A0A9J7K2Y2-1|A0A9J7HCC5_CRIGR Computationally mapped isoform of Centrosomal protein of 290 kDa isoform X1 OS=Cricetulus griseus OX=10029 GN=Cep290 PE=4 SV=1 CANONICAL=A0A9J7HCC5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Y2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Y2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753037", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753037", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "kidney development", "id": "GO:0001822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5" } ], "pmid": "" }, { "name": "ciliary basal body-plasma membrane docking", "id": "GO:0097711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097711", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5" } ], "pmid": "" }, { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5" } ], "pmid": "" }, { "name": "ciliary transition zone assembly", "id": "GO:1905349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905349", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5" } ], "pmid": "" }, { "name": "camera-type eye development", "id": "GO:0043010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043010", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1000, "end_pos": 1002, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1272, "end_pos": 1274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1588, "end_pos": 1590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2562, "end_pos": 2564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2598, "end_pos": 2600, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 587, "end_pos": 589, 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} ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1000, "end_pos": 1002 }, { "start_pos": 1272, "end_pos": 1274 }, { "start_pos": 1588, "end_pos": 1590 }, { "start_pos": 2562, "end_pos": 2564 }, { "start_pos": 2598, "end_pos": 2600 }, { "start_pos": 576, "end_pos": 578 }, { "start_pos": 587, "end_pos": 589 }, { "start_pos": 597, "end_pos": 599 }, { "start_pos": 626, "end_pos": 628 }, { "start_pos": 631, "end_pos": 633 }, { "start_pos": 813, "end_pos": 815 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"monoisotopic_mass": 141786.0 }, "refseq": { "ac": "XP_027247214", "name": "leucine-rich repeat and guanylate kinase domain-containing protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247214" }, "gene_names": [ { "name": "Lrguk", "type": "recommended", "evidence": [ { "id": "A0A9J7J6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6M1" } ] }, { "name": "Lrguk", "type": "synonym", "evidence": [ { "id": "XP_027247214", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247214" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat and guanylate kinase domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A9J7J6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6M1/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat and guanylate kinase domain-containing protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027247214", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247214" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027247214", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247214" } ] }, { "annotation": "Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYM7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYM7#function" }, { "database": "UniProtKB", "id": "ARBA00054148", "url": "https://www.uniprot.org/uniprotkb/ARBA00054148#function" }, { "database": "UniProtKB", "id": "A0A9J7J6M1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6M1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6M1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6M1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lrguk", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6M1", "locus": {} } ], "crossref": [ { "id": "cd00071", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00071", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100750979", "url": "https://www.ncbi.nlm.nih.gov/gene/100750979", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750979", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750979", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CNQISEM", "url": "https://omabrowser.org/oma/group/CNQISEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MYM7", "url": "https://www.orthodb.org/?gene=A0A8C2MYM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J6M1", "url": "https://www.orthodb.org/?gene=A0A9J7J6M1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23117:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23117:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027247214", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247214", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MYM7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MYM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F3K8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F3K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3K8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J6M1", "url": 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"length": 1127, "header": "tr|A0A9J7F3K8-1|A0A9J7J6M1_CRIGR Computationally mapped isoform of Leucine-rich repeat and guanylate kinase domain-containing protein OS=Cricetulus griseus OX=10029 GN=Lrguk PE=4 SV=1 CANONICAL=A0A9J7J6M1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J6M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6M1/entry#A0A9J7J6M1-1", "sequence": { "sequence": "MAASEKGSSRGKASSLQGGLSCAVIQTIRALAAKHRRTPWPPFPMGQKSKGTYRSASSFLLEQLMQRSQEAEDRHGEEESEESVESEIMNLEEDFDGILREEAVAEALSDLGWSGPGTEQVYLNLNLSNCELVDVSVLCDYIHLQKLNLSANKIEDLSCVSHMPYLLELNASQNKLTTFFNFKPPKNLQKVDFSHNEISEMGDLSAYHTLTQLILDNNEIEDISGIENCVCLTHLSLAANKITAINGLGTLPIKVLCLRHNNIETITGLEDLKALQKLDLSYNRISSLQGLENHDLLEMINLEDNKIEELSEIEYIENLPMLRVLNLLKNPIQEKSEYWLFVIFMLLRLTELDQQKIRVEEKVTAVNKYDPPPEVVAVRDHMTHIVNSMSQPQRIFDSTLPSLDAPYPMLVLTGPAACGKRELAHRLCRQFNTYFRYGACHTTRPPYFGEGDRVDYHFISQEVFDEMLSMGKFILTFNYGNHNYGLNRDTIEGIARDGLASCIHLEIEGVRSLKYSYFEPRYILVVPMDKEKYEGYLRRKGLFSRAEIDFTVSRVDIYIKMNRKFPGYFDAVINADDLDIAYKKLSEIIREYLGLTEEVDKGLAPTAAGGPSSKKTISGVPAHLVPSPRRLARLQADGQNPEALLEVQTHSKSPLPQSQESTEEGQPPKKDPSPSSHLNPPQEVSSSTLGNPQPAQDISPKGKVGGGQAAHLPPKIITEMDEPEDEPGPHELKAEGQSSTIASQEPPQHPNPPPQPSPQPDQDKKSGESKGAPRTLPEPAGPDPASLSPQRVQDEGTEPANPAPSSSPHNPPEDPAPSDVVKPTGGSQPPLKDGTPKAEVVRASTPYPEIPPPQDKSTNSKHTQVMEQPMALLPRSRLAPTRLPQPQNLAPLQSRRPTPKLLSPSREEALGTSSDQTPAPSPRSLPTQDDPGKLPLISPPQSKPPPNPSPNAAHSPQQAHAGKASEVKLPLISPPVQEQAQQHSPNPPQEEAAAPTVHFPHIAAPSVEPSLPQNTRPRPASKPAKGRETPKVGHGHASNKKIPGLQASPHSQETAKQKDTRKKNLRQRETAKGSPHLRKIPAGKSQTAQQWESHNKPTPRNVSHPLDSGSPLSHTKATSADPQNQEEKTRKAQNSGKKDLAQSIGTSPNPEMSEGLVQEKVLSENQSIQEAQLPQPAAKSGHGEQAQKKERSQKREVSGKSPEQGTAAPSQLRAKETQALKDSSELRQGYAQRHSIRTSKQQSKEKRTRKNGDAPQSRSPAAPQDQMSEEEPSSRTGRLRARGSQSIKV", "length": 1289, "header": "tr|A0A9J7J6M1-1|A0A9J7J6M1_CRIGR Isoform 1 of Leucine-rich repeat and guanylate kinase domain-containing protein OS=Cricetulus griseus OX=10029 GN=Lrguk PE=4 SV=1 CANONICAL=A0A9J7J6M1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F3K8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3K8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F3K8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3K8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750979", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750979", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GHE9-1", "protein_name": "Leucine-rich repeat and guanylate kinase domain-containing protein", "gene_name": "Lrguk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATFEGSPSRWKGTRFQRSLGASRAVAQAILSLTDKEPQKRWPTFPMGLRSKGTFRSASSYLLHQLIHRSHEAEVEQEEQQEEGESEESEESEMQNLEDEYDGVLREENVADALDGLGWSGRGTEQVYRNLNLSHCELIDVSILSGYVHLQKLNLSGNRIEDLSCVSCMPYLLELNASQNRLTTFFNFKPPQNLKKVDFSSNQISEMYDLSAYHTLTQLILDNNEIEEITGLEKCISLTHLSLAGNRITTIKGLGTLPIKVLSVSNNQIETITGLEELKALQNLDLSHNQISSLHGLENHDLLEVINLEDNKIKELSEIEYIENLPILRVLNLLRNPIQTKPEYWFFVIFMLLRLTELDQQKIKVEEKVYAVNKYDPPPEVVAAQDHMTHVVNSMSQPQRIFDSTLPSLDAPYPMLILTGPEACGKRELAHRLCRQFSTYFRYGACHTTRPPYFGEGDRVDYHFVSQEVFDEMLSMGKFILTFNYGNHNYGLNRDTVEGIARDGLASCIHMELEGIRSLKYSYFEPRYILVVPMDKEKYEGYLRRKGLFSRAEIEIAVSRVDLYVKVNRKFPGYFDAVINADDLDIAYQKLSELIREYLGLTETAKKGLAPTAGASSSKKTVSGVPAHLVPSPRRLARLQADGQKTEAFLEVQPHAMIPENQNPTLPQSQDLTEEGEAPKKEASPSHLDLPQQTQDISPKVKEEDGQPANLPPKITTETEGPEDEPVPPVLEAGQSSTMASQEPPQHPAPAPPLSPQLDQDKESGETKVTPNNPALSEPAQGPDPASVSPQRVQDEGAESANLASSSSTHNLPEDPSHAEIEKPTVGSQPSLKEETPKAEVMRASTPYPEIPPPQDSSTKVREQPVALLPRSRLAPTRLPQPQTLAPLQSRRPTPKLLSPSREEALGTSSEQTPNPSPRSLPTQDGDPSKLPPISPPQSKPPQNPSPHAVHSPQQAQVEKGSEVKLPLISPPVQEQALQHTPKPPQEEEAPTVRLPNIPAPSTEPHLPQNTEPRPASKPARERKTPKVGRASSKKVLDLQATPHSQELTKQKGARKKTLTQRETAKELPHPKKMPIGNSQTAQQPESHSRPTPRNESDALDFRSSPGHTEPVSADPQNREKNRKAHNPRKKAQTNPTPKDASQSTRTSPNGEMSEGLTQGNETALSEDQPTREGQPPQATDQSAQDIAVPSQLRAKESQAQRNTRETRQSYAQRHSILVSKQQSKEKRTRKNGGVPQDRSPAAPQNEVSQEDPGSQTGRLRARGSQSIKV", "length": 1270 }, "evidence": [ { "id": "A0A9J7J6M1", "url": "https://omabrowser.org/oma/group/A0A9J7J6M1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AB32TU23-1", "protein_name": "Leucine-rich repeat and guanylate kinase domain-containing protein", "gene_name": "lrguk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVRSGSVSDRTPAHLPVSLCAISGFYRMTFYWHLNRISDCVWPQGRDLKNVSILCNYIYLQKLELPYNKIKDLSCVSHMPYLITLDASHNQLTDFFGFQPPKNLKEVNFSHNQMTAMKDLSAYSSLTKLILDHNSFSVIRGLEKCKRLSHLSLAHNNISRIRGLDHLPLRELCLAGNMINKIENLQTLHNLQVLDLSCNRIQSLTGLQNLRFLGTVNLESNLITEIKEAAHLHDLILLREINLLKNPVQDHDDYRIAVIFLLQHLILLDKQTVTAEEKVAAVNKYDPPLEVVAARDHMTHLVYQLMQPQVIFDSTLPSLDAPYPMLVLTGPQACGKRELAHKLCQEFSDYFAYGACHTTRGPYFGEEDGLDYHFVTEEEFHNMIQMGQFIQTMQYGGHWYGLSRESIERVAREGLACCVHMELEGVFSLKNSYFEPRYVLLIPSVVDNYVLFLKARGFYSNAQMETAVSRIDLYARINRERPGFFDSIIPCDDRAEAYRSLKQLVKEYLGLEEHSGGGDSSSITPDNTSTNTTGELPAASATESTDLMDSYSRNYQKKIQANMTPQRTEMASNHRRLQQIREALSGKSPGAYAELFQRSVPAAPSSLASQSHPPAGPSSSPVRPAGLSAPNLSEDSSSEESRASSGLSMRSSAGVFSAESPARGSDAGSGPNIEPLDISMLGQDRDSLRGLTPDAPRPASDRVSPTHPSSPGRPGANVKPVLPPIPSGRKTNDSGSKQ", "length": 739 }, "evidence": [ { "id": "A0A9J7J6M1", "url": "https://omabrowser.org/oma/group/A0A9J7J6M1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BAV1-1", "protein_name": "Leucine-rich 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"evidence": [ { "id": "A0A9J7J6M1", "url": "https://omabrowser.org/oma/group/A0A9J7J6M1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96M69-1", "protein_name": "Leucine-rich repeat and guanylate kinase domain-containing protein", "gene_name": "LRGUK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATSERALLRTRAASLLRGLGRSRTGARSLQFRAEKERQPCWSFPMGQKTKGSSNIASSYLLQQLMHRYQELDSDGDEDQGEGEAGSEESSESEMLNLEEEFDGVLREEAVAKALHHLGRSGSGTEQVYLNLTLSGCNLIDVSILCGYVHLQKLDLSANKIEDLSCVSCMPYLLELNASQNNLTTFFNFKPPKNLKKADFSHNQISEICDLSAYHALTKLILDGNEIEEISGLEMCNNLIHLSLANNKITTINGLNKLPIKILCLSNNQIEMITGLEDLKALQNLDLSHNQISSLQGLENHDLLEVINLEDNKIAELREIEYIKNLPILRVLNLLENPIQEKSEYWFFVIFMLLRLTELDQKKIKVEEKVSAVNKYDPPPEVVAAQDHLTHVVNSVMQPQRIFDSTLPSLDAPYPMLILAGPEACGKRELAHRLCRQFSTYFRYGACHTTRPPYFGEGDRVDYHFISQDVFDEMVNMGKFILTFSYGNHKYGLNRDTVEGIARDGLASCIHMEIEGVRSLKYSYFEPRYILVVPMNKEKYEGYLRRKGLFSRAEIEFAVSRVDLYIKINQNFPGYFDEVINADDLDVAYQKLSQLIREYLGLTEEPAKSLATTADVKTSHLKPEAHPTKYISSNMGDFLHSTDRNYLIKFWAKLSAKKTPAERDSIHRQHEAARQALMGRIRPDHTLLFQRGPVPAPLTSGLHYYTTLEELWKSFDLCEDYFKPPFGPYPEKSGKDSLVSMKCSLFRFCPWSKELPFQPPEGSISSHLGSGASDSETEETRKALPIQSFSHEKESHQHRQHSVPVISRPGSNVKPTLPPIPQGRR", "length": 825 }, "evidence": [ { "id": "A0A9J7J6M1", "url": "https://omabrowser.org/oma/group/A0A9J7J6M1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": 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"database": "UniProtKB", "id": "A0A9J7J6M1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6M1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6M1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6M1" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6M1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6M1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1101, "end_pos": 1103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1165, "end_pos": 1167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6M1" }, { "id": "PS50052", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50052" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Guanylate kinase-like", "eco_id": "ECO_0000259", "start_pos": 407, "end_pos": 590, "start_aa": "Tyr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J7N2-1", "uniprot_ac": "A0A9J7J7N2", "uniprot_id": "A0A9J7J7N2_CRIGR", "mass": { "chemical_mass": 29192.0, "monoisotopic_mass": 29192.0 }, "refseq": { "ac": "XP_027243383", "name": "28S ribosomal protein S16, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243383" }, "gene_names": [ { "name": "Mrps16", "type": "recommended", "evidence": [ { "id": "A0A9J7J7N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7N2" } ] }, { "name": "Mrps16", "type": "synonym", "evidence": [ { "id": "XP_027243383", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243383" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein bS16m", "type": "recommended", "evidence": [ { "id": "A0A9J7J7N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7N2/entry#names_and_taxonomy" } ] }, { "name": "28S ribosomal protein S16, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027243383", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243383" } ] }, { "name": "28S ribosomal protein S16, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A9J7J7N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7N2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027243383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243383" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7N2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7N2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mrps16", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7N2", "locus": {} } ], "crossref": [ { "id": "A0A9J7J7N2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J7N2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100762457", "url": "https://www.ncbi.nlm.nih.gov/gene/100762457", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023803", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023803", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762457", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762457", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PNDYNER", "url": "https://omabrowser.org/oma/group/PNDYNER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MYS8", "url": "https://www.orthodb.org/?gene=A0A8C2MYS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J7N2", "url": "https://www.orthodb.org/?gene=A0A9J7J7N2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12919", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12919", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12919:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12919:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00886", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00886", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027243383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243383", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MYS8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MYS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7N2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7N2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGRMCLQRTRQQGRETGPTVSPHSGPTQSPAKDSQRRHAYRHTSSASLQEVRVALLPSGRLRQRKRKRWSERPAASAEGFLDLERCRACACAAAWGAPPGFRLCGVGGCRRDSQRGRSSLHHGPPYYFSTATFLSRAYHGGHLTIRLALGGCANRPFYRIVAAHNKCPRDGRFVEQLGSYDPLPNSNGEKLVALNLDRIRHWIGCGAHLSKPMEKLLGLSGFYPLHPMMITNAERLRRKRAREVLLASQKTESEPGETEAS", "length": 263, "header": "tr|A0A9J7J7N2-1|A0A9J7J7N2_CRIGR Isoform 1 of Small ribosomal subunit protein bS16m OS=Cricetulus griseus OX=10029 GN=Mrps16 PE=3 SV=1 CANONICAL=A0A9J7J7N2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MYS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7N2/entry#A0A8C2MYS8-1", "sequence": { "sequence": "MVHLTTFLSRAYHGGHLTIRLALGGCANRPFYRIVAAHNKCPRDGRFVEQLGSYDPLPNSNGEKLVALNLDRIRHWIGCGAHLSKPMEKLLGLSGFYPLHPMMITNAERLRRKRAREVLLASQKTESEPGETEAS", "length": 135, "header": "tr|A0A8C2MYS8-1|A0A9J7J7N2_CRIGR Computationally mapped isoform of Small ribosomal subunit protein bS16m OS=Cricetulus griseus OX=10029 GN=Mrps16 PE=3 SV=1 CANONICAL=A0A9J7J7N2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J7N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7N2/entry#A0A9J7J7N2-1", "sequence": { "sequence": "MAAGRMCLQRTRQQGRETGPTVSPHSGPTQSPAKDSQRRHAYRHTSSASLQEVRVALLPSGRLRQRKRKRWSERPAASAEGFLDLERCRACACAAAWGAPPGFRLCGVGGCRRDSQRGRSSLHHGPPYYFSTATFLSRAYHGGHLTIRLALGGCANRPFYRIVAAHNKCPRDGRFVEQLGSYDPLPNSNGEKLVALNLDRIRHWIGCGAHLSKPMEKLLGLSGFYPLHPMMITNAERLRRKRAREVLLASQKTESEPGETEAS", "length": 263, "header": "tr|A0A9J7J7N2-1|A0A9J7J7N2_CRIGR Isoform 1 of Small ribosomal subunit protein bS16m OS=Cricetulus griseus OX=10029 GN=Mrps16 PE=3 SV=1 CANONICAL=A0A9J7J7N2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 21, "start_aa": "Thr", "end_pos": 21, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr21", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 29, "start_aa": "Thr", "end_pos": 29, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr29", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYS8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYS8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYS8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYS8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762457", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762457", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P82915-1", "protein_name": "Small ribosomal subunit protein bS16m", "gene_name": "MRPS16", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVQLTTVLCKAYRGGHLTIRLALGGCTNRPFYRIVAAHNKCPRDGRFVEQLGSYDPMPNSHGEKLVALNLDRIRHWIGCGAHLSKPVEKLLGLSGFFPLHPMVITNAERLRRKRAQEVLLAAQKTDTEATETKEN", "length": 135 }, "evidence": [ { "id": "A0A9J7J7N2", "url": "https://omabrowser.org/oma/group/A0A9J7J7N2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CPX7-1", "protein_name": "Small ribosomal subunit protein bS16m", "gene_name": "Mrps16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVQLTTIFCKAYHGGHLTIRLALGGCTNRPFYRIVAAHNKCPRDGRFVEQLGSYDPLPNSHGEKLVALNLDRIRHWIGCGAHLSKPMEKLLGLSGFFPLHPMMITNAERLRRRRAREVLLASQKAESEAKETEAS", "length": 135 }, "evidence": [ { "id": "A0A9J7J7N2", "url": "https://omabrowser.org/oma/group/A0A9J7J7N2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LTS6-1", "protein_name": "Small ribosomal subunit protein bS16m/bS16c", "gene_name": "RPS16-2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVVRIRLSRFGCKNRPFFRVMAADSRSPRDGKHLEVLGYFNPLPGQDGGKRMGLKFDRIKYWLSVGAQPSDPVQRLLFRSGLLPPPPMVAMGRKGGARDTRPVDPMTGRYVDAENKTVNANDNQPKEEDTEAKSA", "length": 135 }, "evidence": [ { "id": "A0A9J7J7N2", "url": "https://omabrowser.org/oma/group/A0A9J7J7N2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9V6Y3-1", "protein_name": "Small ribosomal subunit protein bS16m", "gene_name": "mRpS16", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLSPASGIGRFYAKSAKIIRFVRLGCTNRPFYHIVVMERRKNQHQPVIEQVGSFDPLPNDYNERLVALNTERIRYWLGKGAHLSTPAAELLGIAGLLPIHPRTYMTAWRNRRTAAEAEASPEKAESTA", "length": 129 }, "evidence": [ { "id": "A0A9J7J7N2", "url": "https://omabrowser.org/oma/group/A0A9J7J7N2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y3D3-1", "protein_name": "Small ribosomal subunit protein bS16m", "gene_name": "MRPS16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVHLTTLLCKAYRGGHLTIRLALGGCTNRPFYRIVAAHNKCPRDGRFVEQLGSYDPLPNSHGEKLVALNLDRIRHWIGCGAHLSKPMEKLLGLAGFFPLHPMMITNAERLRRKRAREVLLASQKTDAEATDTEATET", "length": 137 }, "evidence": [ { "id": "A0A9J7J7N2", "url": 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"https://www.uniprot.org/uniprotkb/A0A9J7J7N2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7N2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7N2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 21, 29 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, 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Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027245410", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245410" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7F8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tasor", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F8", "locus": {} } ], "crossref": [ { "id": "cd22569", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22569", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752192", "url": "https://www.ncbi.nlm.nih.gov/gene/100752192", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046432", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046432", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752192", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752192", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7J7F8", "url": "https://www.orthodb.org/?gene=A0A9J7J7F8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16207", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16207", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16207:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16207:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12509", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12509", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23314", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23314", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24630", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24630", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027245410", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245410", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZP5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7C3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7C3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7C3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7F8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATAAETEASSTDASWGSRGFGGDDGMKPALPELESSLQDGGGSGGGAGPEETAAAEAARSHSHEQPQHTSEAAAVALHKGAEEPERPVRRSFQIPRKSREKKALFQSLTPGSREFEDVLNILHSSYLEPSSVTNFNYRRACLIHNELLEKEFTEKRRELKFDGRLDKELSESYAFLMVDRYQVQSICEKGLQVGQSKITILGSPSMGIYLCRYADLLQSNPLEAGAVGDVVIFKIMKGKIKSIYDPLSVKSLEPMLNKNALDPTPKHECHVSKNASRITSLLAYRAYELTQYYFYEYGFDELRRRPRHVCPYAVVSFIYKDEIQTPKFMSSLRSNSFNADRNIEKCNYTLWKGQLLNKGKLLCYISLRSATRAFLPVKLPEKLDVETVMSIDYLKQKIPPALFYKDTYVGPNEVLKNGMYCSLYEVVEKTRIGSNMECLLQKLEKEKLVLVKPLGDRGYLFLLSPYQMTSPYEHQTVKSRILHALFLFQEPRCLIITQKGVTNPLPQEKHENISDILKITQFLQFALIQCRKEFKDINTINFHSVVEKYVSEFFKRGFGSGKREFFMFSYDSRLDDKKFLYSAPRNKSHIDDCLHTYIFQPEMYQLPIFKLKELFEENLKRQQFSPLSDYEGQEEEINGSKMKFGKRNSSRGETTEPSQQKSSHSLDYDKDRVKELINLIQCTKKNVGGDPDTEDTRSKNVLKRKLEDLPENMRKFAKTSSSSDNYHLYEESPQSIGLLGHEPNLRLQQEEACNIGDIHKLYNWLSETLANARHSDAFLTDTVNKALGLSSSGTCEALRQKCEYELNPALDKKDCEQPACTKIENVHFKGAQSPLLEVDAASVKYPTLSTNEDPNLINVNNFEECSLCPTVSIEHGFLRQHSKSNDEEETEIHWKLIPITGGNVRSPEDQHGKHGEKQTPGMKSPGEQLVCLPPLEAFPNDPRVINRERSSDYQFPSSPFTDTVKGTTEEEDLLTGPVMTVEEQCVPAAEPPTVTSETTENTVLGEFHFFSRKIEEILKQKNVSYVSTISTPIFSAQEKMNRLSEFIYSKTSKAGIQEFVDGLHEKLNTIIIKASAKGGNLPPVNPNHSHTTTLNPLGRHVVSISSSDFNSKDLFEPLCPEPLKDNSSNEQYSSSVVIEMNQPHLCKELMLTSDHTVPSDTALESVEKEISKSPNDINISAQPALSNFISQLEPEVFNSLVKIMKDVQKNTVKFYIHEEEESVLCKEIKEYLIKLGNTECHPDQFLERRSTLDKLLIIIQNEDIADFIHKVPGLVTLKKLPCVSFAGVDSLDDVKNHTYNELFVSGGVIVSDESILNPEVVTIESLKIFLAFLEELSTPEGKWQWKIHCKFQKKLKELGRLNTKALSLLSLLNVYQKKHLVEILSYHNCDSQTRNAPEMDCLIRLQAQNIQQRHIVFLTEKTIKMVSSYTDNGIVVATAEDFMHNFKSLVGYHNSVTEENLPLLGANETLESQSALLENGEKDEEDMSLDSGDEISHIEVFSSFHSEILARETKGSSGTDQKKNIQIELQSSLDVQNSLLEDKTYQIDCEERAPIDRVRSEGENSNSAEQDSYSNVQAYQNQLKMSHQFSHFNVLTHQTFLGTPYTLSSTQSQENENYFFSVYKTSDREKSPLS", "length": 1635, "header": "tr|A0A9J7J7F8-1|A0A9J7J7F8_CRIGR Isoform 1 of Protein TASOR isoform X6 OS=Cricetulus griseus OX=10029 GN=Tasor PE=3 SV=1 CANONICAL=A0A9J7J7F8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F8/entry#A0A8C2MZP5-1", "sequence": { "sequence": "MATAAETEASSTDASWGSRGFGGDDGMKPALPELESSLQDGGGSGGGAGPEETAAAEAARSHSHEQPQHTSEAAAVALHKGAEEPERPVRRSFQIPRKSREKKALFQSLTPGSREFEDVLNILHSSYLEPSSVTNFNYRRACLIHNELLEKEFTEKRRELKFDGRLDKELSESYAFLMVDRYQVQSICEKGLQVGQSKITILGSPSMGIYLCRYADLLQSNPLEAGAVGDVVIFKIMKGKIKSIYDPLSVKSLEPMLNKNALDPTPKHECHVSKNASRITSLLAYRAYELTQYYFYEYGFDELRRRPRHVCPYAVVSFIYKDEIQTPKFMSSLRSNSFNADRNIEKCNYTLWKGQLLNKGKLLCYISLRSATRAFLPVKLPEKLDVETVMSIDYLKQKIPPALFYKDTYVGPNEVLKNGMYCSLYEVVEKTRIGSNMECLLQKLEKEKLVLVKPLGDRGYLFLLSPYQMTSPYEHQTVKSRILHALFLFQEPRCLIITQKGVTNPLPQEKHENISDILKITQFLQFALIQCRKEFKDINTINFHSVVEKYVSEFFKRGFGSGKREFFMFSYDSRLDDKKFLYSAPRNKSHIDDCLHTYIFQPEMYQLPIFKLKELFEENLKRQQFSPLSDYEGQEEEINGSKMKFGKRNSSRGETTEPSQQKSSHSLDYDKDRVKELINLIQCTKKNVGGDPDTEDTRSKNVLKRKLEDLPENMRKFAKTSSSSDNYHLYEESPQSIGLLGHEPNLRLQQEEACNIGDIHKLYNWLSETLANARHSDAFLTDTVNKALGLSSSGTCEALRQKCEYELNPALDKKDCEQPACTKIENVHFKGAQSPLLEVDAASVKYPTLSTNEDPNLINVNNFEECSLCPTVSIEHGFLRQHSKSNDEEETEIHWKLIPITGGNVRSPEDQHGKHGEKQTPGMKSPGEQLVCLPPLEAFPNDPRVINRERSSDYQFPSSPFTDTVKGTTEEEDLLTGPVMTVEEQCVPAAEPPTVTSETTENTVLGEFHFFSRKIEEILKQKNVSYVSTISTPIFSAQEKMNRLSEFIYSKTSKAGIQEFVDGLHEKLNTIIIKASAKGGNLPPVNPNHSHTTTLNPLGRHVVSISSSDFNSKDLFEPLCPEPLKDNSSNEQYSSSVVIEMNQPHLCKELMLTSDHTVPSDTALESVEKEISKSPNDINISAQPALSNFISQLEPEVFNSLVKIMKDVQKNTVKFYIHEEEESVLCKEIKEYLIKLGNTECHPDQFLERRSTLDKLLIIIQNEDIADFIHKVPGLVTLKKLPCVSFAGVDSLDDVKNHTYNELFVSGGVIVSDESILNPEVVTIESLKIFLAFLEELSTPEGKWQWKIHCKFQKKLKELGRLNTKALSLLSLLNVYQKKHLVEILSYHNCDSQTRNAPEMDCLIRLQAQNIQQRHIVFLTEKTIKMVSSYTDNGIVVATAEDFMHNFKSLVGYHNSVTEENLPLLGANETLESQSDAVLTLTPLELGVGISQH", "length": 1493, "header": "tr|A0A8C2MZP5-1|A0A9J7J7F8_CRIGR Computationally mapped isoform of Protein TASOR isoform X6 OS=Cricetulus griseus OX=10029 GN=Tasor PE=3 SV=1 CANONICAL=A0A9J7J7F8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J7C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F8/entry#A0A9J7J7C3-1", "sequence": { "sequence": "MATAAETEASSTDASWGSRGFGGDDGMKPALPELESSLQDGGGSGGGAGPEETAAAEAARSHSHEQPQHTSEAAAVALHKGAEEPERPVRRSFQIPRKSREKKALFQSLTPGSREFEDVLNILHSSYLEPSSVTNFNYRRACLIHNELLEKEFTEKRRELKFDGRLDKELSESYAFLMVDRYQVQSICEKGLQVGQSKITILGSPSMGIYLCRYADLLQSNPLEAGAVGDVVIFKIMKGKIKSIYDPLSVKSLEPMLNKNALDPTPKHECHVSKNASRITSLLAYRAYELTQYYFYEYGFDELRRRPRHVCPYAVVSFIYKDEIQTPKFMSSLRSNSFNADRNIEKCNYTLWKGQLLNKGKLLCYISLRSATRAFLPVKLPEKLDVETVMSIDYLKQKIPPALFYKDTYVGPNEVLKNGMYCSLYEVVEKTRIGSNMECLLQKLEKEKLVLVKPLGDRGYLFLLSPYQMTSPYEHQTVKSRILHALFLFQEPRCLIITQKGVTNPLPQEKHENISDILKITQFLQFALIQCRKEFKDINTINFHSVVEKYVSEFFKRGFGSGKREFFMFSYDSRLDDKKFLYSAPRNKSHIDDCLHTYIFQPEMYQLPIFKLKELFEENLKRQQFSPLSDYEGQEEEINGSKMKFGKRNSSRGETTEPSQQKSSHSLDYDKDRVKELINLIQCTKKNVGGDPDTEDTRSKNVLKRKLEDLPENMRKFAKTSSSSDNYHLYEESPQSIGLLGHEPNLRLQQEEACNIGDIHKLYNWLSETLANARHSDAFLTDTVNKALGLSSSGTCEALRQKCEYELNPALDKKDCEQPACTKIENVHFKGAQSPLLEVDAASVKYPTLSTNEDPNLINVNNFEECSLCPTVSIEHGFLRQHSKSNDEEETEIHWKLIPITGMKSPGEQLVCLPPLEAFPNDPRVINRERSSDYQFPSSPFTDTVKGTTEEEDLLTGPVMTVEEQCVPAAEPPTVTSETTENTVLGEFHFFSRKIEEILKQKNVSYVSTISTPIFSAQEKMNRLSEFIYSKTSKAGIQEFVDGLHEKLNTIIIKASAKGGNLPPVNPNHSHTTTLNPLGRHVVSISSSDFNSKDLFEPLCPEPLKDNSSNEQYSSSVVIEMNQPHLCKELMLTSDHTVPSDTALESVEKEISKSPNDINISAQPALSNFISQLEPEVFNSLVKIMKDVQKNTVKFYIHEEEESVLCKEIKEYLIKLGNTECHPDQFLERRSTLDKLLIIIQNEDIADFIHKVPGLVTLKKLPCVSFAGVDSLDDVKNHTYNELFVSGGVIVSDESILNPEVVTIESLKIFLAFLEELSTPEGKWQWKIHCKFQKKLKELGRLNTKALSLLSLLNVYQKKHLVEILSYHNCDSQTRNAPEMDCLIRLQAQNIQQRHIVFLTEKTIKMVSSYTDNGIVVATAEDFMHNFKSLVGYHNSVTEENLPLLGANETLESQSDAVLTLTPLELGVGISQH", "length": 1473, "header": "tr|A0A9J7J7C3-1|A0A9J7J7C3_CRIGR Computationally mapped isoform of Protein TASOR isoform X3 OS=Cricetulus griseus OX=10029 GN=Tasor PE=3 SV=1 CANONICAL=A0A9J7J7F8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J7F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F8/entry#A0A9J7J7F8-1", "sequence": { "sequence": "MATAAETEASSTDASWGSRGFGGDDGMKPALPELESSLQDGGGSGGGAGPEETAAAEAARSHSHEQPQHTSEAAAVALHKGAEEPERPVRRSFQIPRKSREKKALFQSLTPGSREFEDVLNILHSSYLEPSSVTNFNYRRACLIHNELLEKEFTEKRRELKFDGRLDKELSESYAFLMVDRYQVQSICEKGLQVGQSKITILGSPSMGIYLCRYADLLQSNPLEAGAVGDVVIFKIMKGKIKSIYDPLSVKSLEPMLNKNALDPTPKHECHVSKNASRITSLLAYRAYELTQYYFYEYGFDELRRRPRHVCPYAVVSFIYKDEIQTPKFMSSLRSNSFNADRNIEKCNYTLWKGQLLNKGKLLCYISLRSATRAFLPVKLPEKLDVETVMSIDYLKQKIPPALFYKDTYVGPNEVLKNGMYCSLYEVVEKTRIGSNMECLLQKLEKEKLVLVKPLGDRGYLFLLSPYQMTSPYEHQTVKSRILHALFLFQEPRCLIITQKGVTNPLPQEKHENISDILKITQFLQFALIQCRKEFKDINTINFHSVVEKYVSEFFKRGFGSGKREFFMFSYDSRLDDKKFLYSAPRNKSHIDDCLHTYIFQPEMYQLPIFKLKELFEENLKRQQFSPLSDYEGQEEEINGSKMKFGKRNSSRGETTEPSQQKSSHSLDYDKDRVKELINLIQCTKKNVGGDPDTEDTRSKNVLKRKLEDLPENMRKFAKTSSSSDNYHLYEESPQSIGLLGHEPNLRLQQEEACNIGDIHKLYNWLSETLANARHSDAFLTDTVNKALGLSSSGTCEALRQKCEYELNPALDKKDCEQPACTKIENVHFKGAQSPLLEVDAASVKYPTLSTNEDPNLINVNNFEECSLCPTVSIEHGFLRQHSKSNDEEETEIHWKLIPITGGNVRSPEDQHGKHGEKQTPGMKSPGEQLVCLPPLEAFPNDPRVINRERSSDYQFPSSPFTDTVKGTTEEEDLLTGPVMTVEEQCVPAAEPPTVTSETTENTVLGEFHFFSRKIEEILKQKNVSYVSTISTPIFSAQEKMNRLSEFIYSKTSKAGIQEFVDGLHEKLNTIIIKASAKGGNLPPVNPNHSHTTTLNPLGRHVVSISSSDFNSKDLFEPLCPEPLKDNSSNEQYSSSVVIEMNQPHLCKELMLTSDHTVPSDTALESVEKEISKSPNDINISAQPALSNFISQLEPEVFNSLVKIMKDVQKNTVKFYIHEEEESVLCKEIKEYLIKLGNTECHPDQFLERRSTLDKLLIIIQNEDIADFIHKVPGLVTLKKLPCVSFAGVDSLDDVKNHTYNELFVSGGVIVSDESILNPEVVTIESLKIFLAFLEELSTPEGKWQWKIHCKFQKKLKELGRLNTKALSLLSLLNVYQKKHLVEILSYHNCDSQTRNAPEMDCLIRLQAQNIQQRHIVFLTEKTIKMVSSYTDNGIVVATAEDFMHNFKSLVGYHNSVTEENLPLLGANETLESQSALLENGEKDEEDMSLDSGDEISHIEVFSSFHSEILARETKGSSGTDQKKNIQIELQSSLDVQNSLLEDKTYQIDCEERAPIDRVRSEGENSNSAEQDSYSNVQAYQNQLKMSHQFSHFNVLTHQTFLGTPYTLSSTQSQENENYFFSVYKTSDREKSPLS", "length": 1635, "header": "tr|A0A9J7J7F8-1|A0A9J7J7F8_CRIGR Isoform 1 of Protein TASOR isoform X6 OS=Cricetulus griseus OX=10029 GN=Tasor PE=3 SV=1 CANONICAL=A0A9J7J7F8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KDY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F8/entry#A0A9J7KDY7-1", "sequence": { "sequence": "MATAAETEASSTDASWGSRGFGGDDGMKPALPELESSLQDGGGSGGGAGPEETAAAEAARSHSHEQPQHTSEAAAVALHKGAEEPERPVRRSFQIPRKSREKKALFQSLTPGSREFEDVLNILHSSYLEPSSVTNFNYRRACLIHNELLEKEFTEKRRELKFDGRLDKELSESYAFLMVDRYQVQSICEKGLQVGQSKITILGSPSMGIYLCRYADLLQSNPLEAGAVGDVVIFKIMKGKIKSIYDPLSVKSLEPMLNKNALDPTPKHECHVSKNASRITSLLAYRAYELTQYYFYEYGFDELRRRPRHVCPYAVVSFIYKDEIQTPKFMSSLRSNSFNADRNIEKCNYTLWKGQLLNKGKLLCYISLRSATRAFLPVKLPEKLDVETVMSIDYLKQKIPPALFYKDTYVGPNEVLKNGMYCSLYEVVEKTRIGSNMECLLQKLEKEKLVLVKPLGDRGYLFLLSPYQMTSPYEHQTVKSRILHALFLFQEPRCLIITQKGVTNPLPQEKHENISDILKITQFLQFALIQCRKEFKDINTINFHSVVEKYVSEFFKRGFGSGKREFFMFSYDSRLDDKKFLYSAPRNKSHIDDCLHTYIFQPEMYQLPIFKLKELFEENLKRQQFSPLSDYEGQEEEINGSKMKFGKRNSSRGETTEPSQQKSSHSLDYDKDRVKELINLIQCTKKNVGGDPDTEDTRSKNVLKRKLEDLPENMRKFAKTSSSSDNYHLYEESPQSIGLLGHEPNLRLQQEEACNIGDIHKLYNWLSETLANARHSDAFLTDTVNKALGLSSSGTCEALRQKCEYELNPALDKKDCEQPACTKIENVHFKGAQSPLLEVDAASVKYPTLSTNEDPNLINVNNFEECSLCPTVSIEHGFLRQHSKSNDEEETEIHWKLIPITDTVKGTTEEEDLLTGPVMTVEEQCVPAAEPPTVTSETTENTVLGEFHFFSRKIEEILKQKNVSYVSTISTPIFSAQEKMNRLSEFIYSKTSKAGIQEFVDGLHEKLNTIIIKASAKGGNLPPVNPNHSHTTTLNPLGRHVVSISSSDFNSKDLFEPLCPEPLKDNSSNEQYSSSVVIEMNQPHLCKELMLTSDHTVPSDTALESVEKEISKSPNDINISAQPALSNFISQLEPEVFNSLVKIMKDVQKNTVKFYIHEEEESVLCKEIKEYLIKLGNTECHPDQFLERRSTLDKLLIIIQNEDIADFIHKVPGLVTLKKLPCVSFAGVDSLDDVKNHTYNELFVSGGVIVSDESILNPEVVTIESLKIFLAFLEELSTPEGKWQWKIHCKFQKKLKELGRLNTKALSLLSLLNVYQKKHLVEILSYHNCDSQTRNAPEMDCLIRLQAQNIQQRHIVFLTEKTIKMVSSYTDNGIVVATAEDFMHNFKSLVGYHNSVTEENLPLLGANETLESQSDAVLTLTPLELGVGISQH", "length": 1432, "header": "tr|A0A9J7KDY7-1|A0A9J7J7F8_CRIGR Computationally mapped isoform of Protein TASOR isoform X6 OS=Cricetulus griseus OX=10029 GN=Tasor PE=3 SV=1 CANONICAL=A0A9J7J7F8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KEZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F8/entry#A0A9J7KEZ1-1", "sequence": { "sequence": "MATAAETEASSTDASWGSRGFGGDDGMKPALPELESSLQDGGGSGGGAGPEETAAAEAARSHSHEQPQHTSEAAAVALHKGAEEPERPVRRSFQIPRKSREKKALFQSLTPGSREFEDVLNILHSSYLEPSSVTNFNYRRACLIHNELLEKEFTEKRRELKFDGRLDKELSESYAFLMVDRYQVQSICEKGLQVGQSKITILGSPSMGIYLCRYADLLQSNPLEAGAVGDVVIFKIMKGKIKSIYDPLSVKSLEPMLNKNALDPTPKHECHVSKNASRITSLLAYRAYELTQYYFYEYGFDELRRRPRHVCPYAVVSFIYKDEIQTPKFMSSLRSNSFNADRNIEKCNYTLWKGQLLNKGKLLCYISLRSATRAFLPVKLPEKLDVETVMSIDYLKQKIPPALFYKDTYVGPNEVLKNGMYCSLYEVVEKTRIGSNMECLLQKLEKEKLVLVKPLGDRGYLFLLSPYQMTSPYEHQTVKSRILHALFLFQEPRCLIITQKGVTNPLPQEKHENISDILKITQFLQFALIQCRKEFKDINTINFHSVVEKYVSEFFKRGFGSGKREFFMFSYDSRLDDKKFLYSAPRNKSHIDDCLHTYIFQPEMYQLPIFKLKELFEENLKRQQFSPLSDYEGQEEEINGSKMKFGKRNSSRGETTEPSQQKSSHSLDYDKDRVKELINLIQCTKKNVGGDPDTEDTRSKNVLKRKLEDLPENMRKFAKTSSSSDNYHLYEESPQSIGLLGHEPNLRLQQEEACNIGDIHKLYNWLSETLANARHSDAFLTDTVNKALGLSSSGTCEALRQKCEYELNPALDKKDCEQPACTKIENVHFKGAQSPLLEVDAASVKYPTLSTNEDPNLINVNNFEECSLCPTVSIEHGFLRQHSKSNDEEETEIHWKLIPITGGNVRSPEDQHGKHGEKQTPDTVKGTTEEEDLLTGPVMTVEEQCVPAAEPPTVTSETTENTVLGEFHFFSRKIEEILKQKNVSYVSTISTPIFSAQEKMNRLSEFIYSKTSKAGIQEFVDGLHEKLNTIIIKASAKGGNLPPVNPNHSHTTTLNPLGRHVVSISSSDFNSKDLFEPLCPEPLKDNSSNEQYSSSVVIEMNQPHLCKELMLTSDHTVPSDTALESVEKEISKSPNDINISAQPALSNFISQLEPEVFNSLVKIMKDVQKNTVKFYIHEEEESVLCKEIKEYLIKLGNTECHPDQFLERRSTLDKLLIIIQNEDIADFIHKVPGLVTLKKLPCVSFAGVDSLDDVKNHTYNELFVSGGVIVSDESILNPEVVTIESLKIFLAFLEELSTPEGKWQWKIHCKFQKKLKELGRLNTKALSLLSLLNVYQKKHLVEILSYHNCDSQTRNAPEMDCLIRLQAQNIQQRHIVFLTEKTIKMVSSYTDNGIVVATAEDFMHNFKSLVGYHNSVTEENLPLLGANETLESQSDAVLTLTPLELGVGISQH", "length": 1452, "header": "tr|A0A9J7KEZ1-1|A0A9J7J7F8_CRIGR Computationally mapped isoform of Protein TASOR isoform X6 OS=Cricetulus griseus OX=10029 GN=Tasor PE=3 SV=1 CANONICAL=A0A9J7J7F8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDY7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDY7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752192", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752192", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "mesodermal to mesenchymal transition involved in gastrulation", "id": "GO:0060809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060809", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7F8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7F8" } ], "pmid": "" }, { "name": "anterior/posterior axis specification, embryo", "id": "GO:0008595", "url": 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Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027247721", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247721" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8Z1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Z1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Larp1b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Z1", "locus": {} } ], "crossref": [ { "id": "A0A9J7J8Z1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J8Z1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08038", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08038", "database": "CDD", "categories": [ "Protein Classification" ] 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K2X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2X5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSVRRLLELSSPKIIKAGKLKTKKSNKASDFSDMANWPTPGELVNTGSQSVSSQGNKKPQFRKEKEEKIEKRSNSESKENREAKLDGPVENVSEDEAQSSSQRKRANKHKWVPLHLDDVRPDSQERPGSRNSSRCQPEANKPAHSNRKSDTRSWRRDREKRDDQDEVSSVRSEGGTIRGSARGRGRGRGRGRGRGRGNPRLNFDYSYGYREPGERTDQPFPTELNTSMMYYYDDGTGVQVYPVEETLLKEYIKRQIEYYFSTENLERDFFLRRKMDEQGFLPISLIAGFHRVQALTTNLNLILEALKDSTEVEIVDEKMRKRIEPEKWPIPGPPPRNVPQTDFSQLIDCPEFIPGQAFGSHTESAPNSPRIGSPLSPKKHTETSTIRVMSRGLSTSLPDLDLEPWIDVKERHRPSLVILKKSMSVLEETSSQLAFLEEPEREEREFLFDEEMEQTDRRKKTFNDWSDNDSDYEIDDQDLNKILIVTQTPPYMRKHPGGDRTGTHTSPANITSELAEVINDGLYYYEQDLWTEGENLRTAIKVTISEMTSATETHTMPSVVPASPRIHPAWTPKACQMPWLQVPNRTLRFYPVVKEPRAIDVKSPRKRKTSHSTTPPLECHVGWVMDSRDHGPRPPSVSSSNASPSEGAPLTGSCSCTPHSFPKFQHPSHELLKENGFTQQVYHKYRRRCLSERKRLGIGQSQEMNTLFRFWSFFLRDHFNRKMYEEFRQLAWEDAKENYRYGLECLFRFYSYGLEKKFRQEIFKDFQEETKKDYESGQLYGLEKFWAYLKYSQSKTQSVDPKLQEYLCSFKKLEDFRVDPPISEEFGRKRHSSTYGEESNRHRLPSHSSTPPPSVAQSASASEPQEKSSGTQ", "length": 873, "header": "tr|A0A9J7J8Z1-1|A0A9J7J8Z1_CRIGR Isoform 1 of La-related protein 1B isoform X1 OS=Cricetulus 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"MANWPTPGELVNTGSQSVSSQGNKKPQFRKEKEEKIEKRSNSESKENREAKLDGPVENVSEDEAQSSSQRKRANKHKWVPLHLDDVRPDSQERPGSRNSSRCQPEANKPAHSNRKSDTRSWRRDREKRDDQDEVSSVRSEGGTIRGSARGRGRGRGRGRGRGRGNPRLNFDYSYGYREPGERTDQPFPTELNTSMMYYYDDGTGVQVYPVEETLLKEYIKRQIEYYFSTENLERDFFLRRKMDEQGFLPISLIAGFHRVQALTTNLNLILEALKDSTEVEIVDEKMRKRIEPEKWPIPGPPPRNVPQTDFSQLIDCPEFIPGQAFGSHTESAPNSPRIGSPLSPKKHTETSTIRVMSRGLSTSLPDLDLEPWIDVKERHRPSLVILKKSMSVLEETSSQLAFLEEPEREEREFLFDEEMEQTDRRKKTFNDWSDNDSDYEIDDQDLNKILIVTQTPPYMRKHPGGDRTGTHTSPANITSELAEVINDGLYYYEQDLWTEGENLRTAIKK", "length": 509, "header": "tr|A0A9J7F5A9-1|A0A9J7J8Z1_CRIGR Computationally mapped isoform of La-related protein 1B isoform X1 OS=Cricetulus griseus OX=10029 GN=Larp1b PE=3 SV=1 CANONICAL=A0A9J7J8Z1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J8Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Z1/entry#A0A9J7J8Z1-1", "sequence": { "sequence": "MQSVRRLLELSSPKIIKAGKLKTKKSNKASDFSDMANWPTPGELVNTGSQSVSSQGNKKPQFRKEKEEKIEKRSNSESKENREAKLDGPVENVSEDEAQSSSQRKRANKHKWVPLHLDDVRPDSQERPGSRNSSRCQPEANKPAHSNRKSDTRSWRRDREKRDDQDEVSSVRSEGGTIRGSARGRGRGRGRGRGRGRGNPRLNFDYSYGYREPGERTDQPFPTELNTSMMYYYDDGTGVQVYPVEETLLKEYIKRQIEYYFSTENLERDFFLRRKMDEQGFLPISLIAGFHRVQALTTNLNLILEALKDSTEVEIVDEKMRKRIEPEKWPIPGPPPRNVPQTDFSQLIDCPEFIPGQAFGSHTESAPNSPRIGSPLSPKKHTETSTIRVMSRGLSTSLPDLDLEPWIDVKERHRPSLVILKKSMSVLEETSSQLAFLEEPEREEREFLFDEEMEQTDRRKKTFNDWSDNDSDYEIDDQDLNKILIVTQTPPYMRKHPGGDRTGTHTSPANITSELAEVINDGLYYYEQDLWTEGENLRTAIKVTISEMTSATETHTMPSVVPASPRIHPAWTPKACQMPWLQVPNRTLRFYPVVKEPRAIDVKSPRKRKTSHSTTPPLECHVGWVMDSRDHGPRPPSVSSSNASPSEGAPLTGSCSCTPHSFPKFQHPSHELLKENGFTQQVYHKYRRRCLSERKRLGIGQSQEMNTLFRFWSFFLRDHFNRKMYEEFRQLAWEDAKENYRYGLECLFRFYSYGLEKKFRQEIFKDFQEETKKDYESGQLYGLEKFWAYLKYSQSKTQSVDPKLQEYLCSFKKLEDFRVDPPISEEFGRKRHSSTYGEESNRHRLPSHSSTPPPSVAQSASASEPQEKSSGTQ", "length": 873, "header": "tr|A0A9J7J8Z1-1|A0A9J7J8Z1_CRIGR Isoform 1 of La-related protein 1B isoform X1 OS=Cricetulus griseus OX=10029 GN=Larp1b PE=3 SV=1 CANONICAL=A0A9J7J8Z1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K2X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Z1/entry#A0A9J7K2X5-1", "sequence": { "sequence": "MANWPTPGELVNTGSQSVSSQGNKKPQFRKEKEEKIEKRSNSESKENREAKLDGPVENVSEDEAQSSSQRKRANKHKWVPLHLDDVRPDSQERPGSRNSSRCQPEANKPAHSNRKSDTRSWRRDREKRDDQDEVSSVRSEGGTIRGSARGRGRGRGRGRGRGRGNPRLNFDYSYGYREPGERTDQPFPTELNTSMMYYYDDGTGVQVYPVEETLLKEYIKRQIEYYFSTENLERDFFLRRKMDEQGFLPISLIAGFHRVQALTTNLNLILEALKDSTEVEIVDEKMRKRIEPEKWPIPGPPPRNVPQTDFSQLIDCPEFIPGQAFGSHTESAPNSPRIGSPLSPKKHTETSTIRVMSRGLSTSLPDLDLEPWIDVKERHRPSLVILKKSMSVLEETSSQLAFLEEPEREEREFLFDEEMEQTDRRKKTFNDWSDNDSDYEIDDQDLNKILIVTQTPPYMRKHPGGDRTGTHTSPANITSELAEVINDGLYYYEQDLWTEGENLRTAIKVTISEMTSATETHTMPSVVPASPRIHPAWTPKACQMPWLQVPNRTLRFYPVVKEPRAIDVKSPRKRKTSHSTTPPLECHVGWVMDSRDHGPRPPSVSSSNASPSEGAPLTGSCSCTPHSFPKFQHPSHELLKENGFTQQVYHKYRRRCLSERKRLGIGQSQEMNTLFRFWSFFLRDHFNRKMYEEFRQLAWEDAKENYRYGLECLFRFYSYGLEKKFRQEIFKDFQEETKKDYESGQLYGLEKFWAYLKYSQSKTQSVDPKLQEYLCSFKKLEDFRVDPPISEEFGRKRHSSTYGEESNRHRLPSHSSTPPPSVAQSASASEPQEKSSGTQ", "length": 839, "header": "tr|A0A9J7K2X5-1|A0A9J7J8Z1_CRIGR Computationally mapped isoform of La-related protein 1B isoform X1 OS=Cricetulus griseus OX=10029 GN=Larp1b PE=3 SV=1 CANONICAL=A0A9J7J8Z1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 40, "start_aa": "Thr", "end_pos": 40, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr40", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K2X5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2X5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772564", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772564", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8Z1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Z1" } ], "pmid": "" }, { "name": "RNA cap binding", "id": "GO:0000339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000339", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8Z1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Z1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8Z1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Z1" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8Z1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Z1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8Z1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8Z1" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": 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annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027242928", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242928" } ] }, { "annotation": "Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02174", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02174", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027242928", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242928", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MIT3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MIT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MIT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MIT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAT6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HD35", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HD35-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J3W0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3W0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J3W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3W0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEAALVEGQVKLRDGKKWKSRWLVLRKPSPVADCLLMLVYKDRCERSKGLRERSSLTLEDICGLEPALPYEGLAHTLAIICLSQAVMLGFDSHEAMCAWDTRIRYALGEVHRFHVTVAPGTKLESGPATLHLCNDILVLARDIPPAVMGQWKLSDLRRYGAVPNGFIFEGGTRCGYWAGVFFLSSAEGEQISFLFDCIVRGISPTKGPFGLRPVLPDLSPGGPSASEERVAQEALEALQLEKRLSLLSHSGRPGSGGDDRSLSSSSSEASHSDISASSRLTAWPEQSSSSASTSQEGPGLVAAQGPGEAMLGASRPPLKPLRPRQLQEVGRQSSSDSGIATGSHSSYSGSFSSYAGSSLDVWRAGEEFGSLLSLPPGASAPEPKLCACPPGVAEYQVPTSLRHHYDTPRSLRQAPRDPSPASPGGPDHSSATDLGGQAPPSSRRRGQATEGPGSEATLPSPSPGESWEAGSPHSGPPPAFFLSCSVCGGLKVMATSPSGLTVTYPGSPGPMAADSPGLERPRSELPTYVNIPISPTSRLQLHYMGLEFPGASGSVRGASTSRYAQIDITATETAHRVGVRHAQTREERLPELEQRKKGP", "length": 600, "header": "tr|A0A9J7J3W0-1|A0A9J7J3W0_CRIGR Isoform 1 of Protein Dok-7 OS=Cricetulus griseus OX=10029 GN=Dok7 PE=4 SV=1 CANONICAL=A0A9J7J3W0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MIT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3W0/entry#A0A8C2MIT3-1", "sequence": { "sequence": "MTEAALVEGQVKLRDGKKWKSRWLVLRKPSPVAGAGVFFLSSAEGEQISFLFDCIVRGISPTKGPFGLRPVLPDLSPGGPSASEERVAQEALEALQLEKRLSLLSHSGRPGSGGDDRSLSSSSSEASHSDISASSRLTAWPEQSSSSASTSQEGPGLVAAQGPGEAMLGASRPPLKPLRPRQLQEVGRQSSSDSGIATGSHSSYSGSFSSYAGSSLDVWRAGEEFGSLLSLPPGASAPEPKLCACPPGVAEYQVPTSLRHHYDTPRSLRQAPRDPSPASPGGPDHSSATDLGGQAPPSSRRRGQATEGPGSEATLPSPSPGESWEAGSPHSGPPPAFFLSCSVCGGLKVKPPP", "length": 353, "header": "tr|A0A8C2MIT3-1|A0A9J7J3W0_CRIGR Computationally mapped isoform of Protein Dok-7 OS=Cricetulus griseus OX=10029 GN=Dok7 PE=4 SV=1 CANONICAL=A0A9J7J3W0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3W0/entry#A0A9J7HAT6-1", "sequence": { "sequence": "MTEAALVEGQWKSRWLVLRKPSPVADCLLMLVYKDRCERSKGLRERSSLTLEDICGLEPALPYEGLAHTLAIICLSQAVMLGFDSHEAMCAWDTRIRYALGEVHRFHVTVAPGTKLESGPATLHLCNDILVLARDIPPAVMGQWKLSDLRRYGAVPNGFIFEGGTRCGYWAGVFFLSSAEGEQISFLFDCIVRGISPTKGPFGLRPVLPDLSPGGPSASEERVAQEALEALQLEKRLSLLSHSGRPGSGGDDRSLSSSSSEASHSDISASSRLTAWPEQSSSSASTSQEGPGLVAAQGPGEAMLGASRPPLKPLRPRQLQEVGRQSSSDSGIATGSHSSYSGSFSSYAGSSLDVWRAGEEFGSLLSLPPGASAPEPKLCACPPGVAEYQVPTSLRHHYDTPRSLRQAPRDPSPASPGGPDHSSATDLGGQAPPSSRRRGQATEGPGSEATLPSPSPGESWEAGSPHSGPPPAFFLSCSVCGGLKVKPPP", "length": 489, "header": "tr|A0A9J7HAT6-1|A0A9J7HAT6_CRIGR Computationally mapped isoform of Protein Dok-7 isoform X4 OS=Cricetulus griseus OX=10029 GN=Dok7 PE=4 SV=1 CANONICAL=A0A9J7J3W0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HD35-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3W0/entry#A0A9J7HD35-1", "sequence": { "sequence": "MTEAALVEGQVKLRDGKKWKSRWLVLRKPSPVADCLLMLVYKDRCERSKGLRERSSLTLEDICGLEPALPYEGLAHTLAIICLSQAVMLGFDSHEAMCAWDTRIRYALGEVHRFHVTVAPGTKLESGPATLHLCNDILVLARDIPPAVMGQWKLSDLRRYGAVPNGFIFEGGTRCGYWAGVFFLSSAEGEQISFLFDCIVRGISPTKGPFGLRPVLPEPSCSAPSSEERVAQEALEALQLEKRLSLLSHSGRPGSGGDDRSLSSSSSEASHSDISASSRLTAWPEQSSSSASTSQEGPGLVAAQGPGEAMLGASRPPLKPLRPRQLQEVGRQSSSDSGIATGSHSSYSGSFSSYAGSSLDVWRAGEEFGSLLSLPPGASAPEPKLCACPPGVAEYQVPTSLRHHYDTPRSLRQAPRDPSPASPGGPDHSSATDLGGQAPPSSRRRGQATEGPGSEATLPSPSPGESWEAGSPHSGPPPAFFLSCSVCGGLKVKPPP", "length": 496, "header": "tr|A0A9J7HD35-1|A0A9J7HD35_CRIGR Computationally mapped isoform of Protein Dok-7 OS=Cricetulus griseus OX=10029 GN=Dok7 PE=4 SV=1 CANONICAL=A0A9J7J3W0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J3W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3W0/entry#A0A9J7J3W0-1", "sequence": { "sequence": "MTEAALVEGQVKLRDGKKWKSRWLVLRKPSPVADCLLMLVYKDRCERSKGLRERSSLTLEDICGLEPALPYEGLAHTLAIICLSQAVMLGFDSHEAMCAWDTRIRYALGEVHRFHVTVAPGTKLESGPATLHLCNDILVLARDIPPAVMGQWKLSDLRRYGAVPNGFIFEGGTRCGYWAGVFFLSSAEGEQISFLFDCIVRGISPTKGPFGLRPVLPDLSPGGPSASEERVAQEALEALQLEKRLSLLSHSGRPGSGGDDRSLSSSSSEASHSDISASSRLTAWPEQSSSSASTSQEGPGLVAAQGPGEAMLGASRPPLKPLRPRQLQEVGRQSSSDSGIATGSHSSYSGSFSSYAGSSLDVWRAGEEFGSLLSLPPGASAPEPKLCACPPGVAEYQVPTSLRHHYDTPRSLRQAPRDPSPASPGGPDHSSATDLGGQAPPSSRRRGQATEGPGSEATLPSPSPGESWEAGSPHSGPPPAFFLSCSVCGGLKVMATSPSGLTVTYPGSPGPMAADSPGLERPRSELPTYVNIPISPTSRLQLHYMGLEFPGASGSVRGASTSRYAQIDITATETAHRVGVRHAQTREERLPELEQRKKGP", "length": 600, "header": "tr|A0A9J7J3W0-1|A0A9J7J3W0_CRIGR Isoform 1 of Protein Dok-7 OS=Cricetulus griseus OX=10029 GN=Dok7 PE=4 SV=1 CANONICAL=A0A9J7J3W0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 117, "start_aa": "Thr", "end_pos": 117, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr117", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 206, "start_aa": "Thr", "end_pos": 206, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr206", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MIT3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MIT3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MIT3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MIT3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765890", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765890", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neuromuscular junction development", "id": "GO:0007528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007528", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J3W0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3W0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J3W0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3W0" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J3W0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3W0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J3W0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3W0" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J3W0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3W0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J3W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3W0" }, { "id": "PS51064", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51064" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IRS-type PTB", "eco_id": "ECO_0000259", "start_pos": 105, "end_pos": 210, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7J3W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J3W0" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 109, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 117, 206 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HF90-1", "uniprot_ac": "A0A9J7HF90", "uniprot_id": "A0A9J7HF90_CRIGR", "mass": { "chemical_mass": 170836.0, "monoisotopic_mass": 170836.0 }, "refseq": { "ac": "XP_035308589", "name": "tensin-3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308589" }, "gene_names": [ { "name": "Tns3", "type": "recommended", "evidence": [ { "id": "A0A9J7HF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF90" } ] }, { "name": "Tns3", "type": "synonym", "evidence": [ { "id": "XP_035308589", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308589" } ] } ], "protein_names": [ { "name": "Tensin-3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7HF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF90/entry#names_and_taxonomy" } ] }, { "name": "tensin-3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035308589", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308589" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308589", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308589" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF90" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tns3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF90", "locus": {} } ], "crossref": [ { "id": "cd01213", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01213", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09927", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09927", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14561", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14561", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20889", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20889", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754614", "url": "https://www.ncbi.nlm.nih.gov/gene/100754614", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029023", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029023", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754614", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754614", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HAS3", "url": "https://www.orthodb.org/?gene=A0A9J7HAS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7HF90", "url": "https://www.orthodb.org/?gene=A0A9J7HF90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45734", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45734", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45734:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45734:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308589", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308589", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7EVD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EVD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAS3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBQ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDZ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HF90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HF90-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFFKITKCCGHMKPEGFTTCPHSFKKKDFKKPRVCGVCRQTIDGQGIACRACKYSCHKKCEAQVSIPCSVQVHLGQAPESSTPPAALRCDKPSRPLVLSAAMEDSHELDLTYVTERIIAVSFPARCSEESYLHSLQEVTRMLKSKHGDNYLVLNLSEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSDPQHVVVIHCRGGKGRIGVVISSYMHFTNVSASADQALDRFAMKKFYDDKVSALMEPSQKRYVQFLSGLLSGAMKMNASPLFLHFVILHGVPNFDTGGACRPFLKLYQAMQPVYTSGIYNIGPENPSRIRIAIEPAQLLKGDIMVKCYHKKFRSATRDVIFRLQFHTGAVQGYGLLFGKEELDSACKDDRFPDYGKIELVFSATPEKIQGAEHLYCDQGVMVDYNTADPLIRWDSYENMSADGEVLHTQGPVDGSLYAKVRKKSASDSGIPGSPQGMPATSSPDHGDHTLSVSSDSGHSTASARTDKTEERPIPGAQRGLSPQEKAELDQLLSGFGLEDSSSSHKDMTDVRNKYSGTRHVVPAQVHVNGDTALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCLKSSQNSLLSDGFGNGVSEDHHGVLSPDLGLGVDSLYERERMCGGREPKQLQPLLRKPSTPTPPQAYGQSNYSTQTWVRQQQMVAAHQYSFASDGEARLGSHSTVDQPQPHIPVTPTRGASSRVAVQRGISNGPNPPDTQPLCSGKTLQPRFAEDRVMNGGHQDLNTSHSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGISANGSVCPDGVGNGLRCGGRLDPVEGPGRSPGQQGDESIAGRLRKLSLGQYDNDAGSQVSFSKCGWAKASGDPAPSLGPFSSAADIKETMIAAYPPDLDMIDGRISNNKESMCLTPAFPVSPETPYVKTSPRYPPFSPPEPQLSSPASLRKGGREPRGCPEITSHTVGMSESPIGPKPTMLRADMPATPNFQQMFASSCTVSSNGPGQRRESLPSAERQWVESSPKSTLTLLGNSHPSESPRGTHEFCITGKDSPGLPCFQSSELQASFHSHELSMSEPQDALPPAGSQAFLGFNTASVSSGLPPGEDPGALLVNSHGTSPAPGAPLTTAGATDNGFLSHNFLTVSPGPSSHHSPGLQNQGLSLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTMSIPFPNVLPDFCKPSEVATPLPDSPNDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKAPGSFIVRDSHSFRGAYGLAMKVATPPPSVLHLNKKAGDLSNELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAENSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAVQKALSMTLVQEPPPVSTVVHFKVSAQGITLTDNQRNKGISFYSTKHPAGEMTNLPSPSSVILDPSDWNYFLYPPNRLFFRRHYPVSSVIFCALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKI", "length": 1578, "header": "tr|A0A9J7HF90-1|A0A9J7HF90_CRIGR Isoform 1 of Tensin-3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tns3 PE=3 SV=1 CANONICAL=A0A9J7HF90-1" }, "isoforms": [ { "isoform_ac": "A0A9J7EVD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF90/entry#A0A9J7EVD4-1", "sequence": { "sequence": "MEDSHELDLTYVTERIIAVSFPARCSEESYLHSLQEVTRMLKSKHGDNYLVLNLSEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSDPQHVVVIHCRGGKGRIGVVISSYMHFTNVSASADQALDRFAMKKFYDDKVSALMEPSQKRYVQFLSGLLSGAMKMNASPLFLHFVILHGVPNFDTGGACRPFLKLYQAMQPVYTSGIYNIGPENPSRIRIAIEPAQLLKGDIMVKCYHKKFRSATRDVIFRLQFHTGAVQGYGLLFGKEELDSACKDDRFPDYGKIELVFSATPEKIQGAEHLYCDQGVMVDYNTADPLIRWDSYENMSADGEVLHTQGPVDGSLYAKVRKKSASDSGIPGSPQGMPATSSPDHGDHTLSVSSDSGHSTASARTDKTEERPIPGAQRGLSPQEKAELDQLLSGFGLEDSSSSHKDMTDVRNKYSGTRHVVPAQVHVNGDTALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCLKSSQNSLLSDGFGNGVSEDHHGVLSPDLGLGVDSLYERERMCGGREPKQLQPLLRKPSTPTPPQAYGQSNYSTQTWVRQQQMVAAHQYSFASDGEARLGSHSTVDQPQPHIPVTPTRGASSRVAVQRGISNGPNPPDTQPLCSGKTLQPRFAEDRVMNGGHQDLNTSHSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGISANGSVCPDGVGNGLRCGGRLDPVEGPGRSPGQQGDESIAGRLRKLSLGQYDNDAGSQVSFSKCGWAKASGDPAPSLGPFSSAADIKETMIAAYPPDLDMIDGRISNNKESMCLTPAFPVSPETPYVKTSPRYPPFSPPEPQLSSPASLRKGGREPRGCPEITSHTVGMSESPIGPKPTMLRADMPATPNFQQMFASSCTVSSNGPGQRRESLPSAERQWVESSPKSTLTLLGNSHPSESPRGTHEFCITGKDSPGLPCFQSSELQASFHSHELSMSEPQDALPPAGSQAFLGFNTASVSSGLPPGEDPGALLVNSHGTSPAPGAPLTTAGATDNGFLSHNFLTVSPGPSSHHSPGLQNQGLSLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTMSIPFPNVLPDFCKPSEVATPLPDSPNDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKAPGSFIVRDSHSFRGAYGLAMKVATPPPSVLHLNKKAGDLSNELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAENSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAVQKALSMTLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVSSVIFCALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKI", "length": 1437, "header": "tr|A0A9J7EVD4-1|A0A9J7HF90_CRIGR Computationally mapped isoform of Tensin-3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tns3 PE=3 SV=1 CANONICAL=A0A9J7HF90-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF90/entry#A0A9J7HAS3-1", "sequence": { "sequence": "MEDSHELDLTYVTERIIAVSFPARCSEESYLHSLQEVTRMLKSKHGDNYLVLNLSEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSDPQHVVVIHCRGGKGRIGVVISSYMHFTNVSASADQALDRFAMKKFYDDKVSALMEPSQKRYVQFLSGLLSGAMKMNASPLFLHFVILHGVPNFDTGGACRPFLKLYQAMQPVYTSGIYNIGPENPSRIRIAIEPAQLLKGDIMVKCYHKKFRSATRDVIFRLQFHTGAVQGYGLLFGKEELDSACKDDRFPDYGKIELVFSATPEKIQGAEHLYCDQGVMVDYNTADPLIRWDSYENMSADGEVLHTQGPVDGSLYAKVRKKSASDSGIPGSPQGMPATSSPDHGDHTLSVSSDSGHSTASARTDKTEERPIPGAQRGLSPQEKAELDQLLSGFGLEDSSSSHKDMTDVRNKYSGTRHVVPAQVHVNGDTALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCLKSSQNSLLSDGFGNGVSEDHHGVLSPDLGLGVDSLYERERMCGGREPKQLQPLLRKPSTPTPPQAYGQSNYSTQTWVRQQQMVAAHQYSFASDGEARLGSHSTVDQPQPHIPVTPTRGASSRVAVQRGISNGPNPPDTQPLCSGKTLQPRFAEDRVMNGGHQDLNTSHSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGISANGSVCPDGVGNGLRCGGRLDPVEGPGRSPGQQGDESIAGRLRKLSLGQYDNDAGSQVSFSKCGWAKASGDPAPSLGPFSSAADIKETMIAAYPPDLDMIDGRISNNKESMCLTPAFPVSPETPYVKTSPRYPPFSPPEPQLSSPASLRKGGREPRGCPEITSHTVGMSESPIGPKPTMLRADMPATPNFQQMFASSCTVSSNGPGQRRESLPSAERQWVESSPKSTLTLLGNSHPSESPRGTHEFCITGKDSPGLPCFQSSELQASFHSHELSMSEPQDALPPAGSQAFLGFNTASVSSGLPPGEDPGALLVNSHGTSPAPGAPLTTAGATDNGFLSHNFLTVSPGPSSHHSPGLQNQGLSLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTMSIPFPNVLPDFCKPSEVATPLPDSPNDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKAPGSFIVRDSHSFRGAYGLAMKVATPPPSVLHLNKKAGDLSNELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAENSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAVQKALSMTLVQEPPPVSTVVHFKVSAQGITLTDNQRNKGISFYSTKHPAGEMTNLPSPSSVILDPSDWNYFLYPPNRLFFRRHYPVSSVIFCALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKI", "length": 1477, "header": "tr|A0A9J7HAS3-1|A0A9J7HAS3_CRIGR Computationally mapped isoform of Tensin-3 isoform X3 OS=Cricetulus griseus OX=10029 GN=Tns3 PE=3 SV=1 CANONICAL=A0A9J7HF90-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HBQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF90/entry#A0A9J7HBQ3-1", "sequence": { "sequence": "MEDSHELDLTYVTERIIAVSFPARCSEESYLHSLQEVTRMLKSKHGDNYLVLNLSEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSDPQHVVVIHCRGGKGRIGVVISSYMHFTNVSASADQALDRFAMKKFYDDKVSALMEPSQKRYVQFLSGLLSGAMKMNASPLFLHFVILHGVPNFDTGGACRPFLKLYQAMQPVYTSGIYNIGPENPSRIRIAIEPAQLLKGDIMVKCYHKKFRSATRDVIFRLQFHTGAVQGYGLLFGKEELDSACKDDRFPDYGKIELVFSATPEKIQGAEHLYCDQGVMVDYNTADPLIRWDSYENMSADGEVLHTQGPVDGSLYAKVRKKSASDSGIPGSPQGMPATSSPDHGDHTLSVSSDSGHSTASARTDKTEERPIPGAQRGLSPQEKAELDQLLSGFGLEDSSSSHKDMTDVRNKYSGTRHVVPAQVHVNGDTALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCLKSSQNSLLSDGFGNGVSEDHHGVLSPDLGLGVDSLYERERMCGGREPKQLQPLLRKPSTPTPPQAYGQSNYSTQTWVRQQQMVAAHQYSFASDGEARLGSHSTVDQPQPHIPVTPTRGASSRVAVQRGISNGPNPPDTQPLCSGKTLQPRFAEDRVMNGGHQDLNTSHSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGISANGSVCPDGVGNGLRCGGRLDPVEGPGRSPGQQEPRGCPEITSHTVGMSESPIGPKPTMLRADMPATPNFQQMFASSCTVSSNGPGQRRESLPSAERQWVESSPKSTLTLLGNSHPSESPRGTHEFCITGKDSPGLPCFQSSELQASFHSHELSMSEPQDALPPAGSQAFLGFNTASVSSGLPPGEDPGALLVNSHGTSPAPGAPLTTAGATDNGFLSHNFLTVSPGPSSHHSPGLQNQGLSLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTMSIPFPNVLPDFCKPSEVATPLPDSPNDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKAPGSFIVRDSHSFRGAYGLAMKVATPPPSVLHLNKKAGDLSNELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAENSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAVQKALSMTLVQEPPPVSTVVHFKVSAQGITLTDNQRNKGISFYSTKHPAGEMTNLPSPSSVILDPSDWNYFLYPPNRLFFRRHYPVSSVIFCALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKI", "length": 1357, "header": "tr|A0A9J7HBQ3-1|A0A9J7HBQ3_CRIGR Computationally mapped isoform of Tensin-3 isoform X4 OS=Cricetulus griseus OX=10029 GN=Tns3 PE=3 SV=1 CANONICAL=A0A9J7HF90-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HDZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF90/entry#A0A9J7HDZ4-1", "sequence": { "sequence": "MWSSSTAGYVQFLSGLLSGAMKMNASPLFLHFVILHGVPNFDTGGACRPFLKLYQAMQPVYTSGIYNIGPENPSRIRIAIEPAQLLKGDIMVKCYHKKFRSATRDVIFRLQFHTGAVQGYGLLFGKEELDSACKDDRFPDYGKIELVFSATPEKIQGAEHLYCDQGVMVDYNTADPLIRWDSYENMSADGEVLHTQGPVDGSLYAKVRKKSASDSGIPGSPQGMPATSSPDHGDHTLSVSSDSGHSTASARTDKTEERPIPGAQRGLSPQEKAELDQLLSGFGLEDSSSSHKDMTDVRNKYSGTRHVVPAQVHVNGDTALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCLKSSQNSLLSDGFGNGVSEDHHGVLSPDLGLGVDSLYERERMCGGREPKQLQPLLRKPSTPTPPQAYGQSNYSTQTWVRQQQMVAAHQYSFASDGEARLGSHSTVDQPQPHIPVTPTRGASSRVAVQRGISNGPNPPDTQPLCSGKTLQPRFAEDRVMNGGHQDLNTSHSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGISANGSVCPDGVGNGLRCGGRLDPVEGPGRSPGQQGDESIAGRLRKLSLGQYDNDAGSQVSFSKCGWAKASGDPAPSLGPFSSAADIKETMIAAYPPDLDMIDGRISNNKESMCLTPAFPVSPETPYVKTSPRYPPFSPPEPQLSSPASLRKGGREPRGCPEITSHTVGMSESPIGPKPTMLRADMPATPNFQQMFASSCTVSSNGPGQRRESLPSAERQWVESSPKSTLTLLGNSHPSESPRGTHEFCITGKDSPGLPCFQSSELQASFHSHELSMSEPQDALPPAGSQAFLGFNTASVSSGLPPGEDPGALLVNSHGTSPAPGAPLTTAGATDNGFLSHNFLTVSPGPSSHHSPGLQNQGLSLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTMSIPFPNVLPDFCKPSEVATPLPDSPNDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKAPGSFIVRDSHSFRGAYGLAMKVATPPPSVLHLNKKAGDLSNELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAENSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAVQKALSMTLVQEPPPVSTVVHFKVSAQGITLTDNQRNKGISFYSTKHPAGEMTNLPSPSSVILDPSDWNYFLYPPNRLFFRRHYPVSSVIFCALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKI", "length": 1327, "header": "tr|A0A9J7HDZ4-1|A0A9J7HDZ4_CRIGR Computationally mapped isoform of Tensin-3 isoform X5 OS=Cricetulus griseus OX=10029 GN=Tns3 PE=3 SV=1 CANONICAL=A0A9J7HF90-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HF90-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF90/entry#A0A9J7HF90-1", "sequence": { "sequence": "MFFKITKCCGHMKPEGFTTCPHSFKKKDFKKPRVCGVCRQTIDGQGIACRACKYSCHKKCEAQVSIPCSVQVHLGQAPESSTPPAALRCDKPSRPLVLSAAMEDSHELDLTYVTERIIAVSFPARCSEESYLHSLQEVTRMLKSKHGDNYLVLNLSEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSDPQHVVVIHCRGGKGRIGVVISSYMHFTNVSASADQALDRFAMKKFYDDKVSALMEPSQKRYVQFLSGLLSGAMKMNASPLFLHFVILHGVPNFDTGGACRPFLKLYQAMQPVYTSGIYNIGPENPSRIRIAIEPAQLLKGDIMVKCYHKKFRSATRDVIFRLQFHTGAVQGYGLLFGKEELDSACKDDRFPDYGKIELVFSATPEKIQGAEHLYCDQGVMVDYNTADPLIRWDSYENMSADGEVLHTQGPVDGSLYAKVRKKSASDSGIPGSPQGMPATSSPDHGDHTLSVSSDSGHSTASARTDKTEERPIPGAQRGLSPQEKAELDQLLSGFGLEDSSSSHKDMTDVRNKYSGTRHVVPAQVHVNGDTALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCLKSSQNSLLSDGFGNGVSEDHHGVLSPDLGLGVDSLYERERMCGGREPKQLQPLLRKPSTPTPPQAYGQSNYSTQTWVRQQQMVAAHQYSFASDGEARLGSHSTVDQPQPHIPVTPTRGASSRVAVQRGISNGPNPPDTQPLCSGKTLQPRFAEDRVMNGGHQDLNTSHSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGISANGSVCPDGVGNGLRCGGRLDPVEGPGRSPGQQGDESIAGRLRKLSLGQYDNDAGSQVSFSKCGWAKASGDPAPSLGPFSSAADIKETMIAAYPPDLDMIDGRISNNKESMCLTPAFPVSPETPYVKTSPRYPPFSPPEPQLSSPASLRKGGREPRGCPEITSHTVGMSESPIGPKPTMLRADMPATPNFQQMFASSCTVSSNGPGQRRESLPSAERQWVESSPKSTLTLLGNSHPSESPRGTHEFCITGKDSPGLPCFQSSELQASFHSHELSMSEPQDALPPAGSQAFLGFNTASVSSGLPPGEDPGALLVNSHGTSPAPGAPLTTAGATDNGFLSHNFLTVSPGPSSHHSPGLQNQGLSLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTMSIPFPNVLPDFCKPSEVATPLPDSPNDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKAPGSFIVRDSHSFRGAYGLAMKVATPPPSVLHLNKKAGDLSNELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAENSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAVQKALSMTLVQEPPPVSTVVHFKVSAQGITLTDNQRNKGISFYSTKHPAGEMTNLPSPSSVILDPSDWNYFLYPPNRLFFRRHYPVSSVIFCALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKI", "length": 1578, "header": "tr|A0A9J7HF90-1|A0A9J7HF90_CRIGR Isoform 1 of Tensin-3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tns3 PE=3 SV=1 CANONICAL=A0A9J7HF90-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 675, "start_aa": "Thr", "end_pos": 675, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr675", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 728, "start_aa": "Thr", "end_pos": 728, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr728", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EVD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVD4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7EVD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVD4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754614", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754614", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF90" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF90" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF90" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF90" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J503-1", "uniprot_ac": "A0A9J7J503", "uniprot_id": "A0A9J7J503_CRIGR", "mass": { "chemical_mass": 46102.0, "monoisotopic_mass": 46102.0 }, "refseq": { "ac": "XP_027244676", "name": "zinc finger protein 120 isoform X2", 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Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027244676", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244676" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J503", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J503#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J503", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J503" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100753714", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753714", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753714", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7J503", "url": "https://www.orthodb.org/?gene=A0A9J7J503", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF176", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF176", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027244676", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244676", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7F0R9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F0R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0R9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J503", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J503", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J503-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J503-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSAGRRAAGWARPPAGPREQSAVTYDDVHIHFTWEEWALLDLSQKNLYKDVMLETCRNLTAVGCSWEDHNIGEGCQSSGRHRRYERSCTGEKPSEYTQCCTAFACHSHLQRLARIDTVEKPYGGIEYDATFAHHSSLQKQKGKHTGEKPHECNQCGKAFAQHSYLQKHKRIHTGEKPYKCNHCGKAFRRHGHLQRHETIHTGEKPYICNQCGKAFACYSHLQIHKRTHTGEKPYECNQCGKAFACESSLAIHKRTHTGEKPYECNQCGKGFAHHSNLRIHRRTHTGEKPHECHQCGKAFSRHGHLQIHKRSHTGEKPYICNQCGKAFSCNTHLQMHKRTHTGEKPYECIQCGKAFGRHSHLQRHKTTHTGEKPYKCDHCGKAFARRSYLHVHKRTHTGEKP", "length": 402, "header": "tr|A0A9J7J503-1|A0A9J7J503_CRIGR Isoform 1 of Zinc finger protein 120 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100753714 PE=3 SV=1 CANONICAL=A0A9J7J503-1" }, "isoforms": [ { "isoform_ac": "A0A9J7F0R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J503/entry#A0A9J7F0R9-1", "sequence": { "sequence": "MVSAGRRAAGWARPPAGPREQNAVTYDDVHVNFSREEWALLDLSQKNLYKDVMLETYWNLTVIGYNWEDHNIEEHCQTSRRHGR", "length": 84, "header": "tr|A0A9J7F0R9-1|A0A9J7J503_CRIGR Computationally mapped isoform of Zinc finger protein 120 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100753714 PE=3 SV=1 CANONICAL=A0A9J7J503-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J503-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J503/entry#A0A9J7J503-1", "sequence": { "sequence": "MVSAGRRAAGWARPPAGPREQSAVTYDDVHIHFTWEEWALLDLSQKNLYKDVMLETCRNLTAVGCSWEDHNIGEGCQSSGRHRRYERSCTGEKPSEYTQCCTAFACHSHLQRLARIDTVEKPYGGIEYDATFAHHSSLQKQKGKHTGEKPHECNQCGKAFAQHSYLQKHKRIHTGEKPYKCNHCGKAFRRHGHLQRHETIHTGEKPYICNQCGKAFACYSHLQIHKRTHTGEKPYECNQCGKAFACESSLAIHKRTHTGEKPYECNQCGKGFAHHSNLRIHRRTHTGEKPHECHQCGKAFSRHGHLQIHKRSHTGEKPYICNQCGKAFSCNTHLQMHKRTHTGEKPYECIQCGKAFGRHSHLQRHKTTHTGEKPYKCDHCGKAFARRSYLHVHKRTHTGEKP", "length": 402, "header": "tr|A0A9J7J503-1|A0A9J7J503_CRIGR Isoform 1 of Zinc finger protein 120 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100753714 PE=3 SV=1 CANONICAL=A0A9J7J503-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F0R9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0R9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F0R9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0R9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753714", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753714", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J503", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J503" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J503", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J503" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J503", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J503" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J503", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J503" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J503", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J503" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J503", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J503" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7J503", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J503" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 151, "end_pos": 178, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7J503", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J503" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 107, "start_aa": "Val", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7J8R2-1", "uniprot_ac": "A0A9J7J8R2", "uniprot_id": "A0A9J7J8R2_CRIGR", "mass": { "chemical_mass": 45797.0, "monoisotopic_mass": 45797.0 }, "refseq": { "ac": "XP_003510776", "name": "26S proteasome regulatory subunit 10B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510776" }, "gene_names": [ { "name": "Psmc6", "type": "recommended", "evidence": [ { "id": "A0A9J7J8R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8R2" } ] }, { "name": "Psmc6", "type": "synonym", "evidence": [ { "id": "XP_003510776", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510776" } ] } ], "protein_names": [ { "name": "26S proteasome regulatory subunit 10B", "type": "recommended", "evidence": [ { "id": "A0A9J7J8R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8R2/entry#names_and_taxonomy" } ] }, { "name": "26S proteasome AAA-ATPase subunit RPT4", "type": "synonym", "evidence": [ { "id": "A0A9J7J8R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8R2/entry#names_and_taxonomy" } ] }, { "name": "26S proteasome regulatory subunit 10B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003510776", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510776" } ] }, { "name": "Proteasome 26S subunit ATPase 6", "type": "synonym", "evidence": [ { "id": "A0A9J7J8R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8R2/entry#names_and_taxonomy" } ] }, { "name": "Proteasome subunit p42", "type": "synonym", "evidence": [ { "id": "A0A9J7J8R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8R2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614947.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003510776.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510776", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510776" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J8R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8R2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Psmc6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8R2", "locus": {} } ], "crossref": [ { "id": "A0A9J7J8R2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J8R2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19502", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19502", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762558", "url": "https://www.ncbi.nlm.nih.gov/gene/100762558", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050221", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050221", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762558", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762558", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7J8R2", "url": "https://www.orthodb.org/?gene=A0A9J7J8R2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23073", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23073", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16450", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16450", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17862", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17862", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510776", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510776", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7F1A8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F1A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1A8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8R2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8R2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8R2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027247091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247091" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6J0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6J0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Purg", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6J0", "locus": {} } ], "crossref": [ { "id": "A0A9J7J6J0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J6J0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100756819", "url": "https://www.ncbi.nlm.nih.gov/gene/100756819", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006628", 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F3F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3F2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7F3F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3F2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756819", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756819", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6J0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6J0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6J0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6J0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6J0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6J0" } ], "pmid": "" }, { "name": "purine-rich negative regulatory element binding", "id": "GO:0032422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032422", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6J0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6J0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], 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CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027244376", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244376" } ] }, { "annotation": "Required for efficient Cap- and IRES-mediated mRNA translation initiation. Not involved in the ribosome biogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Z0#function" }, { "database": "UniProtKB", "id": "ARBA00058318", "url": "https://www.uniprot.org/uniprotkb/ARBA00058318#function" }, { "database": "UniProtKB", "id": "A0A9J7J6T0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6T0#function" }, { "database": "UniProtKB", "id": "A0A061INL5", "url": "https://www.uniprot.org/uniprotkb/A0A061INL5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6T0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6T0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Abcf1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6T0", "locus": {} } ], "crossref": [ { "id": "A0A9J7J6T0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J6T0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03221", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03221", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765933", "url": "https://www.ncbi.nlm.nih.gov/gene/100765933", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765933", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765933", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7J6T0", "url": "https://www.orthodb.org/?gene=A0A9J7J6T0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19211", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19211", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19211:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19211:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027244376", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244376", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061INL5", "url": "https://www.uniprot.org/uniprotkb/A0A061INL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061INL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061INL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J6T0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6T0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J6T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6T0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKAPKQQPPEPKWFGSGEDTSPEEKVVKKGKKDKKTKKTFFEELAVEDKQAGEEEKTQKEKEQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEEEKELMERLKKLSVPAVDEDQVSAPVPRGGKKAKGGNVFEALIQDESEEEEEEEEEKHAPKPAKPEKNRINKAVSEEQQPGLRSRRGKEEKSKAKAKPQNKFAALDSEEEDDEETTEEKEPPKPGKDREKAKNAEQGEEEEGEEEDGRTKPNDPYANLSKKEKKKLKKQMDYERQVESLKAANAAENDFSVSQAEVSSRQAMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEQERQLQGQLEQGDDTAAEKLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWKKTLLIVSHDQGFLDDVCTDIIHLDTQRLHYYRGNYMTFKKMYQQKQKELVKQYEKQEKKLKELKAGGKSTKQAEKQTKEVLTRKQQKCRRKNQDEESQEPPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYLQRSFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYQGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFDDYKREVLEALGEVMVNRPRD", "length": 843, "header": "tr|A0A9J7J6T0-1|A0A9J7J6T0_CRIGR Isoform 1 of ATP-binding cassette sub-family F member 1 OS=Cricetulus griseus OX=10029 GN=Abcf1 PE=4 SV=1 CANONICAL=A0A9J7J6T0-1" }, "isoforms": [ { "isoform_ac": "A0A061INL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6T0/entry#A0A061INL5-1", "sequence": { "sequence": "MPKAPKQQPPEPKWFGSGEDTSPEEKVVKKGKKDKKTKKTFFEELAVEDKQAGEEEKTQKEKEQQQQQQQQKKKRDTRKGRRKKDVDDDGEEEEKELMERLKKLSVPAVDEDQVSAPVPRGGKKAKGGNVFEALIQDESEEEEEEEEEKHAPKPAKPEKNRINKAVSEEQQPGLRSRRGKEEKSKAKAKPQNKFAALDSEEEDDEETTEEKEPPKPGKDREKAKNAEQGEEEEGEEEDGRTKPNDPYANLSKKEKKKLKKQMDYERQVESLKAANAAENDFSVSQAEVSSRQAMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEQERQLQGQLEQGDDTAAEKLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWKKTLLIVSHDQGFLDDVCTDIIHLDTQRLHYYRGNYMTFKKMYQQKQKELVKQYEKQEKKLKELKAGGKSTKQAEKQTKEVLTRKQQKCRRKNQDEESQEPPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYLQRSFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYQGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFDDYKREVLEALGEVMVNRPRD", "length": 842, "header": "tr|A0A061INL5-1|A0A061INL5_CRIGR Computationally mapped isoform of ATP-binding cassette sub-family F member 1 OS=Cricetulus griseus OX=10029 GN=Abcf1 PE=4 SV=1 CANONICAL=A0A9J7J6T0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6T0/entry#A0A9J7H7Z0-1", "sequence": { "sequence": "MPKAPKQQPPEPKWFGSGEDTSPEEKVVKKGKKDKKTKKTFFEELAVEDKQAGEEEKTQKEKEQQQQQQQKKKRDTRKGRRKKDVDDDGEEEEKELMERLKKLSVPAVDEDQVSAPVPRGGKKAKGGNVFEALIQDESEEEEEEEEEKHAPKPAKPEKNRINKAVSEEQQPGLRSRRGKEEKSKAKAKPQNKFAALDSEEEDDEETTEEKEPPKPGKDREKAKNAEQGEEEEGEEEDGRTKPNDPYANLSKKEKKKLKKQMDYERQVESLKAANAAENDFSVSQAEVSSRQAMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEQERQLQGQLEQGDDTAAEKLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWKKTLLIVSHDQGFLDDVCTDIIHLDTQRLHYYRGNYMTFKKMYQQKQKELVKQYEKQEKKLKELKAGGKSTKQAEKQTKEVLTRKQQKCRRKNQDEESQEPPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYLQRSFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYQGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFDDYKREVLEALGEVMVNRPRD", "length": 841, "header": "tr|A0A9J7H7Z0-1|A0A9J7J6T0_CRIGR Computationally mapped isoform of ATP-binding cassette sub-family F member 1 OS=Cricetulus griseus OX=10029 GN=Abcf1 PE=4 SV=1 CANONICAL=A0A9J7J6T0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J6T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6T0/entry#A0A9J7J6T0-1", "sequence": { "sequence": "MPKAPKQQPPEPKWFGSGEDTSPEEKVVKKGKKDKKTKKTFFEELAVEDKQAGEEEKTQKEKEQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEEEKELMERLKKLSVPAVDEDQVSAPVPRGGKKAKGGNVFEALIQDESEEEEEEEEEKHAPKPAKPEKNRINKAVSEEQQPGLRSRRGKEEKSKAKAKPQNKFAALDSEEEDDEETTEEKEPPKPGKDREKAKNAEQGEEEEGEEEDGRTKPNDPYANLSKKEKKKLKKQMDYERQVESLKAANAAENDFSVSQAEVSSRQAMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEQERQLQGQLEQGDDTAAEKLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWKKTLLIVSHDQGFLDDVCTDIIHLDTQRLHYYRGNYMTFKKMYQQKQKELVKQYEKQEKKLKELKAGGKSTKQAEKQTKEVLTRKQQKCRRKNQDEESQEPPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYLQRSFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYQGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFDDYKREVLEALGEVMVNRPRD", "length": 843, "header": "tr|A0A9J7J6T0-1|A0A9J7J6T0_CRIGR Isoform 1 of ATP-binding cassette sub-family F member 1 OS=Cricetulus griseus OX=10029 GN=Abcf1 PE=4 SV=1 CANONICAL=A0A9J7J6T0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Z0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H7Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7Z0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765933", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765933", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6T0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6T0" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6T0", 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"https://www.uniprot.org/uniprotkb/A0A9J7HCB5" } ], "pmid": "" }, { "name": "peptide antigen binding", "id": "GO:0042605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042605", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB5" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB5" } ], "pmid": "" }, { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030670", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB5" } ], "pmid": "" }, { "name": "MHC class I protein complex", "id": "GO:0042612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042612", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB5" } ], "pmid": "" }, { "name": "lumenal side of endoplasmic reticulum membrane", "id": "GO:0098553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098553", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HCB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB5" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 207, "end_pos": 285, "start_aa": "Pro", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"monoisotopic_mass": 61629.0 }, "refseq": { "ac": "XP_027294947", "name": "zinc finger protein Eos isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027294947" }, "gene_names": [ { "name": "Ikzf4", "type": "recommended", "evidence": [ { "id": "A0A9J7HCF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCF8" } ] }, { "name": "Ikzf4", "type": "synonym", "evidence": [ { "id": "XP_027294947", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027294947" } ] } ], "protein_names": [ { "name": "Zinc finger protein Eos isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7HCF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCF8/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein Eos isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027294947", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027294947" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614217.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027294947.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027294947", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027294947" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCF8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ikzf4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCF8", "locus": {} } ], "crossref": [ { "id": "A0A9J7HCF8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HCF8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100768259", "url": "https://www.ncbi.nlm.nih.gov/gene/100768259", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768259", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768259", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HCF8", "url": "https://www.orthodb.org/?gene=A0A9J7HCF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027294947", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027294947", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H933", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H933", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H933-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H933-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAR6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAR6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPICLLERDPSGGCAPDFLPQAQDSNHFIMESLFCESSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLDKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQGLSTEAQALAGQPGDEIRDLEMVPDSMLHSSSERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNPSSGYEKDVELVSHHGLEPGFGGSLAFVGTEHLRPLRLPPTNCISELTPVISSVYTQMQPLPSRLELPGSREAGEGPEDLGDGGPLLYRARGSLTDPGASPSNGCQDSTDTESNHEDRIGGVVSLPQGPPPQPPPPIVVGRHSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG", "length": 564, "header": "tr|A0A9J7HCF8-1|A0A9J7HCF8_CRIGR Isoform 1 of Zinc finger protein Eos isoform X1 OS=Cricetulus griseus OX=10029 GN=Ikzf4 PE=3 SV=1 CANONICAL=A0A9J7HCF8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H933-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCF8/entry#A0A9J7H933-1", "sequence": { "sequence": "MAAPICLLERDPSGGCAPDFLPQAQDSNHFIMESLFCESSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLDKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQGDEIRDLEMVPDSMLHSSSERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNPSSGYEKDVELVSHHGLEPGFGGSLAFVGTEHLRPLRLPPTNCISELTPVISSVYTQMQPLPSRLELPGSREAGEGPEDLGDGGPLLYRARGSLTDPGASPSNGCQDSTDTESNHEDRIGGVVSLPQGPPPQPPPPIVVGRHSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG", "length": 551, "header": "tr|A0A9J7H933-1|A0A9J7HCF8_CRIGR Computationally mapped isoform of Zinc finger protein Eos isoform X1 OS=Cricetulus griseus OX=10029 GN=Ikzf4 PE=3 SV=1 CANONICAL=A0A9J7HCF8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HCF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCF8/entry#A0A9J7HCF8-1", "sequence": { "sequence": "MAAPICLLERDPSGGCAPDFLPQAQDSNHFIMESLFCESSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLDKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQGLSTEAQALAGQPGDEIRDLEMVPDSMLHSSSERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNPSSGYEKDVELVSHHGLEPGFGGSLAFVGTEHLRPLRLPPTNCISELTPVISSVYTQMQPLPSRLELPGSREAGEGPEDLGDGGPLLYRARGSLTDPGASPSNGCQDSTDTESNHEDRIGGVVSLPQGPPPQPPPPIVVGRHSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG", "length": 564, "header": "tr|A0A9J7HCF8-1|A0A9J7HCF8_CRIGR Isoform 1 of Zinc finger protein Eos isoform X1 OS=Cricetulus griseus OX=10029 GN=Ikzf4 PE=3 SV=1 CANONICAL=A0A9J7HCF8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCF8/entry#A0A9J7KAR6-1", "sequence": { "sequence": "MDIEDFNGRSYMSGSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLDKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQGLSTEAQALAGQPGDEIRDLEMVPDSMLHSSSERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNPSSGYEKDVELVSHHGLEPGFGGSLAFVGTEHLRPLRLPPTNCISELTPVISSVYTQMQPLPSRLELPGSREAGEGPEDLGDGGPLLYRARGSLTDPGASPSNGCQDSTDTESNHEDRIGGVVSLPQGPPPQPPPPIVVGRHSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG", "length": 539, "header": "tr|A0A9J7KAR6-1|A0A9J7HCF8_CRIGR Computationally mapped isoform of Zinc finger protein Eos isoform X1 OS=Cricetulus griseus OX=10029 GN=Ikzf4 PE=3 SV=1 CANONICAL=A0A9J7HCF8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 221, "start_aa": "Thr", "end_pos": 221, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr221", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAR6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAR6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"categories": [ "Protein" ] }, { "id": "A0A9J7HBN8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCL0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K3K8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K3K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3K8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDQ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEP9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEQ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNNQDAVVSILHECKRVLDHLLLETPDVSTEDKSEDQRCRASLPRELRTLIQEAKEMKWPFVPEKWQYKQAMSPEDKTNLQDMIGARLQQLLSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVALLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSMDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLEKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSTIPSSDRSHTLSHASYLRDSAMIDDTVVIPGHQVSALAKEAERNCYRLSWGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVSFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYAKESESDQEQEEEIGMTSEKNDETESTETSVLKSHLVNEVPVLASPDLLSEVSEMKQDLIKMTAILTTDVSDKAGSIKVKELAKAAEEEPGEPFEIVERVKEDLEKVDAILRSGACVREEGRVQTSQSERELEEEWVIVSDEEIQEAKQHAPAEITEQPCIEVRVDRGSKVKSEKDSTGLVTYLTEDLNSYTSSHEKKPQTAQEKTGETSQASGVAKTSENNKGKTVPAEEKQSAQKQPKPSLVIKKPVRRKLKEKQKQKEEGSQGSEETTELKKGSSEESVDEDRGLAPEPLPTAKATSPLIEETPIGSIKDKVKALQKKVEDEQKGRSKLPVRVKGKEDVPKKTTPRTHPAVSPSSKSSPSSKTEKHSSFSSSAKTERHTPVSPSSKTEKHSPVSPSPKNERHSPVSSSKPEKHSPGSPSTKNERHSPVSSVKTERHTPVSPSGKTDKRPPVPSSGRTEKHPPVSPGRTEKRLPVSPSARTSEKQSGKNDKHLPVSPGKTEKQPPVSPTSKTERIEETMSVRELMKAFQSGQDPSKHKTGLFEHKSTKQKQSQDKSKTRAEKEKGHTVTQRESQRTESQTIKRGQRFPVTAPTESRRFRSTTITVGLRTEDPVREKFERAPIIKTPEPVPSVVAEESPRGSEILQDKMMDEQGDMDLQISPDRKTSTDFSDVIKQELEDNDKYQQFRLTEETEKAQIHLDQVITSPFNTTFPLDYMKDEFLPALSLQSGALAGSLESLKQEVIAGSPCGSLMEGTPQVSSEESYKHEGLAETPETSPESLSFSPKKSEEQIGEIKETKVEMPTEIHSEKELPLTKDITDSSGTQGAVVTGGSETSTEHCQKEVTQDPSQDVSSKLDGCPSRHSVSLADETCQVFTEKGSCDESQLPIVGSACKTQAKSETQESTTPSEVGKAFSSSDASGKAGEGTEPKPQGAIRSPQGLELPLPSRDSETLSPVADESLAVSHKDSLEASPVLEDNSSHKTPDSLEPSPLKESPCRDSLESSPVEPKMKAGILPSHFPLPAAIAKTDLVAEVASMRSRLLRDPDGSAEDDSLEQTSLMESSGKSPLSPDTPSSEEVSYEVTPKASDSSIPKPAVIHECAEEEDSENGEKKRFTPEEEMFKMVTKIKTFDELEQEAKQKRDYRKEPRQDGSSSASDPDADCSVEVDEQKPVETMEGETEVPVLVTSESRKASSSSESEPELTQLSKGADSGLLMEPVIRVQPPSPLPSSIDSNSSPEESQFQPIVSKQYTFKMNEDIQEEPGKSEEDKDCQSPLAEGCRTPSADGVDRSYDDLNRETHRSETCDGHGCEVVSPSKSATLVSLGVQSPACIDVDEQLAIDKESLALQDTWEKGRELDPSGVESTQADFPGGSSSLSSSSHCAVSERKESVKEVPSPSSTEKVDVTVTDQTLGSMPKDCPTQDSSSTTQTDRVDTDTLVSDLAETDENSDPQITSPYENVPSSSFFSGEDSRIQTDTCHTTVVCPPEVFSVVIRSSSEDVVKTNSSGRAVSSQESKFETQGLKTESEEKTSLWGMQSDVPSTSVASATPNAPAVIGEQVSKVIITKTDVDSDSWSEIREDDEAFEARVKEEEQKIFGLMVDRQSQGTTPDTTPARTPTEEGTPTSEQNPFLFQEGKLFEMTRSGAIDMTKRSYTDENLHFFQIGQESNEETIPEDLKEGTMGAEPTQPENTSESLELSESKEEVDDEGELLPDDVSEETEELPASDTNLDSQVMISASTEMPTKEAVSTEAQDLPTMQLSDTSSLSTVKQTPCPAFPQPIVQLDFSTVTRSVHSDRDDESPDSSPEEQKSVIEIPTAPMENVPSAESKPQISLRTLSTSVPVPSSTEDESAFSDDFPSGMDEESKEDEAKPKSKIPIKAPTQRTEWQLSYPDTSLQKTAVPQGQDMLSRAPDGRSKSESDANPLDAKTKCPVKARSYIETETESRERAEGFESESEEGATKPKLFASRLPVKSRSTPSSSRTGMSPTKESREHFFDLYRNSIEFFEEISDEASKLVDRLTQSEREQEPPSDDESSSALEVSVIENLPPVETENSVPEDIFDTRPIWDESIETMIERIPDENGHDRAEDPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTILIECLTKINRMDIVHLLETNTEPLQERMGHSYAEMEQTIVLDNSEGFSVLQEELCVARHKQKEEQAASKESESSDHPPMVSEEDISVGYSTFQDCIPKTEGDSPAATLSPQMHPEPAQQDFSGKMQDQQEYYVTTPGAEGAETQKATEVPDSLCKTPEDISTPAEEAKSCLQTPVTSERGSPIVQEPEEAPEPNEEKSPRKTSLVIVESADDQPQVLEGLDSDTAFQKGDDMPDIPPETVSEEEYVDENGHTVVKKVTRKIIRRYVSSDGMEKEEITMQGTPQEPVNIEDGDSYSKVIKRVVLKSDTQQSEVTLSEPSILSSTSQFQAEPVEGRRVSKVVKTTVVHGERMEKSLGDSSLATDLPSAKDDFEEDNNE", "length": 4012, "header": "tr|A0A9J7HCT3-1|A0A9J7HCT3_CRIGR Isoform 1 of Ankyrin-2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Ank2 PE=4 SV=1 CANONICAL=A0A9J7HCT3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H9E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3/entry#A0A9J7H9E0-1", "sequence": { "sequence": "MNNQDAVVSILHECKRVLDHLLLETPDVSTEDKSEDQRCRASLPRELRTLIQEAKEMKWPFVPEKWQYKQAMSPEDKTNLQDMIGARLQQLLSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVALLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSMDVAKLLLQRRAAADSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLEKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAMIDDTVVIPGHQVSALAKEAERNCYRLSWGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVSFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYAKESESDQEQEEEIGMTSEKNPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTILIECLTKINRMDIVHLLETNTEPLQERMGHSYAEMEQTIVLDNSEGFSVLQEELCVARHKQKEEQAASKESESSDHPPMVSEEDISVGYSTFQDCIPKTEGDSPAATLSPQMHPEPAQQDFSGKMQDQQEYYVTTPGAEGAETQKATEVPDSLCKTPEDISTPAEEAKSCLQTPVTSERGSPIVQEPEEAPEPNEEKSPRKTSLVIVESADDQPQVLEGLDSDTAFQKGDDMPDIPPETVSEEEYVDENGHTVVKKVTRKIIRRYVSSDGMEKEEITMQGTPQEPVNIEDGDSYSKVIKRVVLKSDTQQSEVTLSEPSILSSTSQFQAEPVEGRRVSKVVKTTVVHGERMEKSLGDSSLATDLPSAKDDFEEDNNE", "length": 1913, "header": "tr|A0A9J7H9E0-1|A0A9J7H9E0_CRIGR Computationally mapped isoform of Ankyrin-2 isoform X7 OS=Cricetulus griseus OX=10029 GN=Ank2 PE=4 SV=1 CANONICAL=A0A9J7HCT3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3/entry#A0A9J7H9L2-1", "sequence": { "sequence": "MTTMLQKSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVALLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSMDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLEKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAMIDDTVVIPGHQVSALAKEAERNCYRLSWGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVSFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYAKESESDQEQEEEIGMTSEKNPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTILIECLTKINRMDIVHLLETNTEPLQERMGHSYAEMEQTIVLDNSEGFSVLQEELCVARHKQKEEQAASKESESSDHPPMVSEEDISVGYSTFQDCIPKTEGDSPAATLSPQMHPEPAQQDFSGKMQDQQEYYVTTPGAEGAETQKATEVPDSLCKTPEDISTPAEEAKSCLQTPVTSERGSPIVQEPEEAPEPNEEKSPRKTSLVIVESADDQPQVLEGLDSDTAFQKELTEELGELEASSDEEAMVTTRVVRRRVIIQGDDMPDIPPETVSEEEYVDENGHTVVKKVTRKIIRRYVSSDGMEKEEITMQGTPQEPVNIEDGDSYSKVIKRVVLKSDTQQSEVTLSEPSILSSTSQFQAEPVEGRRVSKVVKTTVVHGERMEKSLGDSSLATDLPSAKDDFEEDNNE", "length": 1892, "header": "tr|A0A9J7H9L2-1|A0A9J7HCT3_CRIGR Computationally mapped isoform of Ankyrin-2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Ank2 PE=4 SV=1 CANONICAL=A0A9J7HCT3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3/entry#A0A9J7HAE6-1", "sequence": { "sequence": "MNNQDAVVSILHECKRVLDHLLLETPDVSTEDKSEDQRCRASLPRELRTLIQEAKEMKWPFVPEKWQYKQAMSPEDKTNLQDMIGARLQQLLSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVALLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSMDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLEKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAMIDDTVVIPGHQVSALAKEAERNCYRLSWGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVSFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYAKESESDQEQEEEIGMTSEKNPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTILIECLTKINRMDIVHLLETNTEPLQERMGHSYAEMEQTIVLDNSEGFSVLQEELCVARHKQKEEQAASKESESSDHPPMVSEEDISVGYSTFQDCIPKTEGDSPAATLSPQMHPEPAQQDFSGKMQDQQEYYVTTPGAEGAETQKATEVPDSLCKTPEDISTPAEEAKSCLQTPVTSERGSPIVQEPEEAPEPNEEKSPRKTSLVIVESADDQPQVLEGLDSDTAFQKELTEELGELEASSDEEAMVTTRVVRRRVIIQGDDMPDIPPETVSEEEYVDENGHTVVKKVTRKIIRRYVSSDGMEKEEITMQGTPQEPVNIEDGDSYSKVIKRVVLKSDTQQSEVTLSEPSILSSTSQFQAEPVEGRRVSKVVKTTVVHGERMEKSLGDSSLATDLPSAKDDFEEDNNE", "length": 1977, "header": "tr|A0A9J7HAE6-1|A0A9J7HCT3_CRIGR Computationally mapped isoform of Ankyrin-2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Ank2 PE=4 SV=1 CANONICAL=A0A9J7HCT3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HBN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3/entry#A0A9J7HBN8-1", "sequence": { "sequence": "MNNQDAVVSILHECKRVLDHLLLETPDVSTEDKSEDQRCRASLPRELRTLIQEAKEMKWPFVPEKWQYKQAMSPEDKTNLQDMIGARLQQLLSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVALLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSMDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLEKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAMIDDTVVIPGHQVSALAKEAERNCYRLSWGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVSFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYAKIGMTSEKNPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTILIECLTKINRMDIVHLLETNTEPLQERMGHSYAEMEQTIVLDNSEGFSVLQEELCVARHKQKEEQAASKESESSDHPPMVSEEDISVGYSTFQDCIPKTEGDSPAATLSPQMHPEPAQQDFSGKMQDQQEYYVTTPGAEGAETQKATEVPDSLCKTPEDISTPAEEAKSCLQTPVTSERGSPIVQEPEEAPEPNEEKSPRKTSLVIVESADDQPQVLEGLDSDTAFQKELTEELGELEASSDEEAMVTTRVVRRRVIIQGDDMPDIPPETVSEEEYVDENGHTVVKKVTRKIIRRYVSSDGMEKEEITMQGTPQEPVNIEDGDSYSKVIKRVVLKSDTQQSEVTLSEPSILSSTSQFQAEPVEGRRVSKVVKTTVVHGERMEKSLGDSSLATDLPSAKDDFEEDNNE", "length": 1966, "header": "tr|A0A9J7HBN8-1|A0A9J7HCT3_CRIGR Computationally mapped isoform of Ankyrin-2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Ank2 PE=4 SV=1 CANONICAL=A0A9J7HCT3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HCL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3/entry#A0A9J7HCL0-1", "sequence": { "sequence": "MNNQDAVVSILHECKRVLDHLLLETPDVSTEDKSEDQRCRASLPRELRTLIQEAKEMKWPFVPEKWQYKQAMSPEDKTNLQDMIGARLQQLLSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVALLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSMDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLEKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAMIDDTVVIPGHQVSALAKEAERNCYRLSWGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVSFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYAKESESDQEQEEEIGMTSEKNPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTILIECLTKINRMDIVHLLETNTEPLQERMGHSYAEMEQTIVLDNSEGFSVLQEELCVARHKQKEEQAASKESESSDHPPMVSEEDISVGYSTFQDCIPKTEGDSPAATLSPQMHPEPAQQDFSGKMQDQQEYYVTTPGAEGAETQKATEVPDSLCKTPEDISTPAEEAKSCLQTPVTSERGSPIVQEPEEAPEPNEEKSPRKTSLVIVESADDQPQVLEGLDSDTAFQKGDDMPDIPPETVSEEEYVDENGHTVVKKVTRKIIRRYVSSDGMEKEEITMQGTPQEPVNIEDGDSYSKVIKRVVLKSDTQQSEVTLSEPSILSSTSQFQAEPVEGRRVSKVVKTTVVHGERMEKSLGDSSLATDLPSAKDDFEEDNNE", "length": 1880, "header": "tr|A0A9J7HCL0-1|A0A9J7HCL0_CRIGR Computationally mapped isoform of Ankyrin-2 isoform X9 OS=Cricetulus griseus OX=10029 GN=Ank2 PE=4 SV=1 CANONICAL=A0A9J7HCT3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HCT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3/entry#A0A9J7HCT3-1", "sequence": { "sequence": "MNNQDAVVSILHECKRVLDHLLLETPDVSTEDKSEDQRCRASLPRELRTLIQEAKEMKWPFVPEKWQYKQAMSPEDKTNLQDMIGARLQQLLSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVALLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSMDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLEKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSTIPSSDRSHTLSHASYLRDSAMIDDTVVIPGHQVSALAKEAERNCYRLSWGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVSFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYAKESESDQEQEEEIGMTSEKNDETESTETSVLKSHLVNEVPVLASPDLLSEVSEMKQDLIKMTAILTTDVSDKAGSIKVKELAKAAEEEPGEPFEIVERVKEDLEKVDAILRSGACVREEGRVQTSQSERELEEEWVIVSDEEIQEAKQHAPAEITEQPCIEVRVDRGSKVKSEKDSTGLVTYLTEDLNSYTSSHEKKPQTAQEKTGETSQASGVAKTSENNKGKTVPAEEKQSAQKQPKPSLVIKKPVRRKLKEKQKQKEEGSQGSEETTELKKGSSEESVDEDRGLAPEPLPTAKATSPLIEETPIGSIKDKVKALQKKVEDEQKGRSKLPVRVKGKEDVPKKTTPRTHPAVSPSSKSSPSSKTEKHSSFSSSAKTERHTPVSPSSKTEKHSPVSPSPKNERHSPVSSSKPEKHSPGSPSTKNERHSPVSSVKTERHTPVSPSGKTDKRPPVPSSGRTEKHPPVSPGRTEKRLPVSPSARTSEKQSGKNDKHLPVSPGKTEKQPPVSPTSKTERIEETMSVRELMKAFQSGQDPSKHKTGLFEHKSTKQKQSQDKSKTRAEKEKGHTVTQRESQRTESQTIKRGQRFPVTAPTESRRFRSTTITVGLRTEDPVREKFERAPIIKTPEPVPSVVAEESPRGSEILQDKMMDEQGDMDLQISPDRKTSTDFSDVIKQELEDNDKYQQFRLTEETEKAQIHLDQVITSPFNTTFPLDYMKDEFLPALSLQSGALAGSLESLKQEVIAGSPCGSLMEGTPQVSSEESYKHEGLAETPETSPESLSFSPKKSEEQIGEIKETKVEMPTEIHSEKELPLTKDITDSSGTQGAVVTGGSETSTEHCQKEVTQDPSQDVSSKLDGCPSRHSVSLADETCQVFTEKGSCDESQLPIVGSACKTQAKSETQESTTPSEVGKAFSSSDASGKAGEGTEPKPQGAIRSPQGLELPLPSRDSETLSPVADESLAVSHKDSLEASPVLEDNSSHKTPDSLEPSPLKESPCRDSLESSPVEPKMKAGILPSHFPLPAAIAKTDLVAEVASMRSRLLRDPDGSAEDDSLEQTSLMESSGKSPLSPDTPSSEEVSYEVTPKASDSSIPKPAVIHECAEEEDSENGEKKRFTPEEEMFKMVTKIKTFDELEQEAKQKRDYRKEPRQDGSSSASDPDADCSVEVDEQKPVETMEGETEVPVLVTSESRKASSSSESEPELTQLSKGADSGLLMEPVIRVQPPSPLPSSIDSNSSPEESQFQPIVSKQYTFKMNEDIQEEPGKSEEDKDCQSPLAEGCRTPSADGVDRSYDDLNRETHRSETCDGHGCEVVSPSKSATLVSLGVQSPACIDVDEQLAIDKESLALQDTWEKGRELDPSGVESTQADFPGGSSSLSSSSHCAVSERKESVKEVPSPSSTEKVDVTVTDQTLGSMPKDCPTQDSSSTTQTDRVDTDTLVSDLAETDENSDPQITSPYENVPSSSFFSGEDSRIQTDTCHTTVVCPPEVFSVVIRSSSEDVVKTNSSGRAVSSQESKFETQGLKTESEEKTSLWGMQSDVPSTSVASATPNAPAVIGEQVSKVIITKTDVDSDSWSEIREDDEAFEARVKEEEQKIFGLMVDRQSQGTTPDTTPARTPTEEGTPTSEQNPFLFQEGKLFEMTRSGAIDMTKRSYTDENLHFFQIGQESNEETIPEDLKEGTMGAEPTQPENTSESLELSESKEEVDDEGELLPDDVSEETEELPASDTNLDSQVMISASTEMPTKEAVSTEAQDLPTMQLSDTSSLSTVKQTPCPAFPQPIVQLDFSTVTRSVHSDRDDESPDSSPEEQKSVIEIPTAPMENVPSAESKPQISLRTLSTSVPVPSSTEDESAFSDDFPSGMDEESKEDEAKPKSKIPIKAPTQRTEWQLSYPDTSLQKTAVPQGQDMLSRAPDGRSKSESDANPLDAKTKCPVKARSYIETETESRERAEGFESESEEGATKPKLFASRLPVKSRSTPSSSRTGMSPTKESREHFFDLYRNSIEFFEEISDEASKLVDRLTQSEREQEPPSDDESSSALEVSVIENLPPVETENSVPEDIFDTRPIWDESIETMIERIPDENGHDRAEDPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTILIECLTKINRMDIVHLLETNTEPLQERMGHSYAEMEQTIVLDNSEGFSVLQEELCVARHKQKEEQAASKESESSDHPPMVSEEDISVGYSTFQDCIPKTEGDSPAATLSPQMHPEPAQQDFSGKMQDQQEYYVTTPGAEGAETQKATEVPDSLCKTPEDISTPAEEAKSCLQTPVTSERGSPIVQEPEEAPEPNEEKSPRKTSLVIVESADDQPQVLEGLDSDTAFQKGDDMPDIPPETVSEEEYVDENGHTVVKKVTRKIIRRYVSSDGMEKEEITMQGTPQEPVNIEDGDSYSKVIKRVVLKSDTQQSEVTLSEPSILSSTSQFQAEPVEGRRVSKVVKTTVVHGERMEKSLGDSSLATDLPSAKDDFEEDNNE", "length": 4012, "header": "tr|A0A9J7HCT3-1|A0A9J7HCT3_CRIGR Isoform 1 of Ankyrin-2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Ank2 PE=4 SV=1 CANONICAL=A0A9J7HCT3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K3K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3/entry#A0A9J7K3K8-1", "sequence": { "sequence": "MNNQDAVVSILHECKRVLDHLLLETPDVSTEDKSEDQRCRASLPRELRTLIQEAKEMKWPFVPEKWQYKQAMSPEDKTNLQDMIGARLQQLLSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVALLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSMDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLEKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSSDRSHTLSHASYLRDSAMIDDTVVIPGHQVSALAKEAERNCYRLSWGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVSFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYAKIGMTSEKNPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTILIECLTKINRMDIVHLLETNTEPLQERMGHSYAEMEQTIVLDNSEGFSVLQEELCVARHKQKEEQAASKESESSDHPPMVSEEDISVGYSTFQDCIPKTEGDSPAATLSPQMHPEPAQQDFSGKMQDQQEYYVTTPGAEGAETQKATEVPDSLCKTPEDISTPAEEAKSCLQTPVTSERGSPIVQEPEEAPEPNEEKSPRKTSLVIVESADDQPQVLEGLDSDTAFQKELTEELGELEASSDEEAMVTTRVVRRRVIIQGDDMPDIPPETVSEEEYVDENGHTVVKKVTRKIIRRYVSSDGMEKEEITMQGTPQEPVNIEDGDSYSKVIKRVVLKSDTQQSEVTLSEPSILSSTSQFQAEPVEGRRVSKVVKTTVVHGERMEKSLGDSSLATDLPSAKDDFEEDNNE", "length": 1961, "header": "tr|A0A9J7K3K8-1|A0A9J7HCT3_CRIGR Computationally mapped isoform of Ankyrin-2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Ank2 PE=4 SV=1 CANONICAL=A0A9J7HCT3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KDQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3/entry#A0A9J7KDQ2-1", "sequence": { "sequence": "MNNQDAVVSILHECKRVLDHLLLETPDVSTEDKSEDQRCRASLPRELRTLIQEAKEMKWPFVPEKWQYKQAMSPEDKTNLQDMIGARLQQLLSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVALLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSMDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLEKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAMIDDTVVIPGHQVSALAKEAERNCYRLSWGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVSFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYAKESESDQEQEEEIGMTSEKNPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTILIECLTKINRMDIVHLLETNTEPLQERMGHSYAEMEQTIVLDNSEGFSVLQEELCVARHKQKEEQAASKESESSDHPPMVSEEDISVGYSTFQDCIPKTEGDSPAATLSPQMHPEPAQQDFSGKMQDQQEYYVTTPGAEGAETQKATEVPDSLCKTPEDISTPAEEAKSCLQTPVTSERGSPIVQEPEEAPEPNEEKSPRKTSLVIVESADDQPQVLEGLDSDTAFQKELTEELGELEASSDEEAMVTTRVVRRRVIIQGDDMPDIPPETVSEEEYVDENGHTVVKKVTRKIIRRYVSSDGMEKEEITMQGTPQEPVNIEDGDSYSKVIKRVVLKSDTQQSEVTLSEPSILSSTSQFQAEPVEGRRVSKVVKTTVVHGERMEKSLGDSSLATDLPSAKDDFEEDNNE", "length": 1944, "header": "tr|A0A9J7KDQ2-1|A0A9J7HCT3_CRIGR Computationally mapped isoform of Ankyrin-2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Ank2 PE=4 SV=1 CANONICAL=A0A9J7HCT3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KEP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3/entry#A0A9J7KEP9-1", "sequence": { "sequence": "MNNQDAVVSILHECKRVLDHLLLETPDVSTEDKSEDQRCRASLPRELRTLIQEAKEMKWPFVPEKWQYKQAMSPEDKTNLQDMIGARLQQLLSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVALLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSMDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLEKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAMIDDTVVIPGHQVSALAKEAERNCYRLSWGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVSFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYAKESESDQEQEEEIGMTSEKNPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTILIECLTKINRMDIVHLLETNTEPLQERMGHSYAEMEQTIVLDNSEGFSVLQEELCVARHKQKEEQAASKESESSDHPPMVSEEDISVGYSTFQDCIPKTEGDSPAATLSPQMHPEPAQQDFSGKMQDQQEYYVTTPGAEGAETQKATEVPDSLCKTPEDISTPAEEAKSCLQTPVTSERGSPIVQEPEEAPEPNEEKSPRKTSLVIVESADDQPQVLEGLDSDTAFQKGDDMPDIPPETVSEEEYVDENGHTVVKKVTRKIIRRYVSSDGMEKEEITMQGTPQEPVNIEDGDSYSKVIKRVVLKSDTQQSEVTLSEPSILSSTSQFQAEPVEGRRVSKVVKTTVVHGERMEKSLGDSSLATDLPSAKDDFEEDNNE", "length": 1946, "header": "tr|A0A9J7KEP9-1|A0A9J7HCT3_CRIGR Computationally mapped isoform of Ankyrin-2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Ank2 PE=4 SV=1 CANONICAL=A0A9J7HCT3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KEQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3/entry#A0A9J7KEQ4-1", "sequence": { "sequence": "MNNQDAVVSILHECKRVLDHLLLETPDVSTEDKSEDQRCRASLPRELRTLIQEAKEMKWPFVPEKWQYKQAMSPEDKTNLQDMIGARLQQLLAALRASILVQDCAAAAAIVFLMDRFLYGLDVSGKLLQVAKGLHKLQPATPIAPQVVIRQARISVNSGKLLKAEYILSSLINNNGATGTWLYRNESDKVLVQSVCIQIRGQILQKLGMWYEAAELIWASVVGYLTLPQPDKKGISTSLGILADIFVSMSKTDYEKFKNSPQVNLALLKEFDHHLLSAAEACKLAAAFSAYTPLFVLTAVNIRGTCLLSYGCSTDCPPGLKSLYLCDAKEAFEIGLLTKKDGELVSGKQELHSFIRAAFGLTTVHCRLHGETDAVRAARQLCSEAVGKLYIFSTSYTSQDREALSREIMGLVSQVKGHLQVQSFPKLDDRSYVPESFKCGLDKPILHGHVAFQQILETYSQHHTSVCEVFESTCGNSKNPRDTKPEVCITALKTETNTVDTMGATPEKPCSQEGRGIASSQMAEKDQEKLRRVRRRNWTHSEAFRVSLDQDMGTETEPPSHSNGRADVPLTSLSDSHSSSSWSKLSGLSSSASWEEVNCGVEVMARKESSKEEHLVDTQCSTAVSEEPRCNRSCRATHLLFSKLHGVSLQETEDCNLESSQSQLYKHSSLTPILPFNTTDTCLASNIGLLEVPEGNQDIRNEGPSNTSLQSSPSYGSVSWSLSSSGKFTDMATYPSVQEEENCEMISYCPETKYDFKDHCGGKNRGKVTERFTGPAFTDGPSSADPEGETEESKGDEPSHSQAVPKYLEGNHSMLTHRTFSPCLSVQNVDSAKTGSSAKDQTIDPDASTEDEKGQLLDSTEVYPIGQDGAHRAGAWRPGQRDERPNSSVGGHSPFPDLDADFSTTEENKELGSMLKCSQNSSSSLQWWWKSPTFSNSSLEGESSWSLLNSSRSSFVSLPGQSRTELFEARTLQPDDFEKLLAGVTNDWLLQRLENTGVLKPNQLQRAYNALLLKYSKKSELWTAQETVVYLGEYLKVKKKGKQRNAFWVHYLHQEEILGRYVGKEYKEWKGLRHHFTDVERQMTAQHYVTEFNKRLYEQKIPTQIFYIPSTVLLILEDNTIKGCISVEPYILGEFVKLSNNTKVVKTEYKATEYGLAYGHFSYEFSKHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQKDVTTNFGKRGIFYFFNNQHTSCNEICHRLSLTRPSLEKPSNM", "length": 1242, "header": "tr|A0A9J7KEQ4-1|A0A9J7HCT3_CRIGR Computationally mapped isoform of Ankyrin-2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Ank2 PE=4 SV=1 CANONICAL=A0A9J7HCT3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K3K8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3K8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K3K8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3K8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757830", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757830", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" }, { "name": "intercalated disc", "id": "GO:0014704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014704", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" }, { "name": "T-tubule", "id": "GO:0030315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030315", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" }, { "name": "regulation of potassium ion transport", "id": "GO:0043266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043266", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" }, { "name": "regulation of monoatomic cation transmembrane transport", "id": "GO:1904062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904062", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" }, { "name": "cytoplasmic pattern recognition receptor signaling pathway", "id": "GO:0002753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002753", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" }, { "name": "monosaccharide binding", "id": "GO:0048029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048029", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCT3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027245061", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245061" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J791", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J791" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100758624", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J791", "locus": {} } ], "crossref": [ { "id": "A0A9J7J791", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J791", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03784", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03784", "database": "CDD", "categories": [ "Protein 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"MPVKWMPLLLLLLQLTCCFRSGNCGKVLVWPMEYSHWLNLKIILDELAQRGHEVTVLRPSASIFLDPQKSPDLKFESFPTSLNKDDLDEVFLSLVNKWIYEIPRDSCLSYSPLLQDVCERYSDSYLSLCKDTVSNKQLMTKLQKSKFDVLLSDAIAPCGELIAELLEIPFLYSFRFSPGYTMEKYSGGLLVPPSYVPIILSGLGGKMTFMERVRNMICMLYFDFWFQSFNKKKWDQFYSETLGKHTTLAETIGKAEMWLIRSYWDLEFPRPTLPNVEYVGGLHCKPANPLPKEMEDFVQSSGEHGVVVFSLGSMVSNMTEEKANTIAWALAQIPQKVLWKFDGKTPDTLGPNTRIFKWLPQNDLLGHPKTKAFVTHGGANGIYEAIHFGIPMIGIPLFGEQHDNIAYMVAKGAAVALNFRTITRSDLLNALEAVIENPTYKENAMWLSTIHNDQPMKPLDRAVFWIEFVMRHKGAKHLRPLAYNLTWYQYYSLDVIGFLLAWVAVITFLVIKSCLFIYQKFVKTGKKMKNE", "length": 531, "header": "tr|A0A9J7J791-1|A0A9J7J791_CRIGR Isoform 1 of UDP-glucuronosyltransferase OS=Cricetulus griseus OX=10029 GN=LOC100758624 PE=3 SV=1 CANONICAL=A0A9J7J791-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HA19-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J791/entry#A0A9J7HA19-1", "sequence": { "sequence": 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA19", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA19" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HA19", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HA19" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758624", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758624", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J791", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J791" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J791", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J791" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21032", "name": "", "equation": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8C2LC88-1", "A0A9J7EXN4-1", "A0A9J7EYT5-1", "A0A8C2QNV3-1", "A0A9J7EYX8-1", "A0A9J7F177-1", "A0A9J7F3C1-1", "A0A9J7F3E0-1", "A0A9J7F403-1", "A0A9J7F4V9-1", "A0A061IPR5-1", "A0A9J7J791-1", "A0A9J7J756-1", "A0A9J7HBH5-1", "A0A9J7J9T2-1" ], "evidence": [ { "id": "21032", "database": "Rhea", 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Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027245060", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245060" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J756", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J756" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100762380", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J756", "locus": {} } ], "crossref": [ { "id": "A0A9J7J756", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J756", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03784", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03784", "database": "CDD", "categories": [ "Protein 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"A0A9J7HEH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH3" } ] }, { "name": "Jakmip1", "type": "synonym", "evidence": [ { "id": "XP_035308817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308817" } ] } ], "protein_names": [ { "name": "Janus kinase and microtubule-interacting protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7HEH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH3/entry#names_and_taxonomy" } ] }, { "name": "janus kinase and microtubule-interacting protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035308817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308817" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308817", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308817" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Jakmip1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH3", "locus": {} } ], "crossref": [ { "id": "A0A9J7HEH3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HEH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100771253", "url": "https://www.ncbi.nlm.nih.gov/gene/100771253", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771253", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771253", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HEH3", "url": "https://www.orthodb.org/?gene=A0A9J7HEH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18935", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18935", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18935:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18935:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308817", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308817", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HBG7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC35", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC35-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDR8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HEH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HEH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HFM8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HFM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKKGRSKGEKPETETDSVQMANEELRAKLTNIQIEFQQEKSKVGKLRERLQEAKLEREQEQRRHTAYISELKAKLHEEKTKELQALREALIRQHEQEAARTAKIKEGELQRLQATLNVLRDGAADKVKTALLAEAREEARRTFDGERQRLQQEILELKAARKQAEEALSNCMQADKAKAADLRAAYQAHQDEVHRIKRECERDIRRLMDEIKGKERVILALEKELGVQAGQTQRLLLQKEALDEQLVQVKEAERHHSSPKRELPPGIGDMAELMGGQDQHMDERDVRRFQLKIAELNSVIRKLEDRNTLLADERNELLKRSRETEVQLKPLVEKNKRMNKKNEDLLHSIQRMEEKLKTLTRENVEMKEKLSAQASLKRHTSLTDLSLTRDEQEIEFLRLQVLEQQHVIDDLSLERERLLRSKRHRGKSLKPPKKHVVETFFGFDEESVDSETLSETSYNTDRTDRTPATPEEDLDETTTREEADLRFCQLTREYQALQRAYALLQEQVGGTLDAEREARTREQLQADLLRCQAKIEDLEKLLVEKGQDSAWVEEKQVLMRTNQDLLEKIYRLEMEENQLKSEMQDAKDQNELLEFRVLELEERERRSPAFNLQITTFPENNSSALQLFCHQEGVKGVNISELMKNLDILGDNGNLRNEEQVAVIQAGTVLALCEKWLKQIEGTEAALTQKMMDLEKEKDLFSRQKGYLEQELDYRKEALDQAYLVGPEKIQDLEATLYNALQQEPGRRASEALSASQREDLQAAVEKVRRQLLRQSREFDSQILRERMELLQQAQQKIREMEGKLELQRRQLKELEEKFLFLFLFFSLAFILWP", "length": 835, "header": "tr|A0A9J7HEH3-1|A0A9J7HEH3_CRIGR Isoform 1 of Janus kinase and microtubule-interacting protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Jakmip1 PE=3 SV=1 CANONICAL=A0A9J7HEH3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HBG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH3/entry#A0A9J7HBG7-1", "sequence": { "sequence": "MSKKGRSKGEKPETETDSVQMANEELRAKLTNIQIEFQQEKSKVGKLRERLQEAKLEREQEQRRHTAYISELKAKLHEEKTKELQALREALIRQHEQEAARTAKIKEGELQRLQATLNVLRDGAADKVKTALLAEAREEARRTFDGERQRLQQEILELKAARKQAEEALSNCMQADKAKAADLRAAYQAHQDEVHRIKRECERDIRRLMDEIKGKERVILALEKELGVQAGQTQRLLLQKEALDEQLVQVKEAERHHSSPKRELPPGIGDMDQHMDERDVRRFQLKIAELNSVIRKLEDRNTLLADERNELLKRSRETEVQLKPLVEKNKRMNKKNEDLLHSIQRMEEKLKTLTRENVEMKEKLSAQASLKRHTSLTDLSLTRDEQEIEFLRLQVLEQQHVIDDLSLERERLLRSKRHRGKSLKPPKKHVVETFFGFDEESVDSETLSETSYNTDRTDRTPATPEEDLDETTTREEADLRFCQLTREYQALQRAYALLQEQVGGTLDAEREARTREQLQADLLRCQAKIEDLEKLLVEKGQDSAWVEEKQVLMRTNQDLLEKIYRLEMEENQLKSEMQDAKDQNELLEFRVLELEERERRSPAFNLQITTFPENNSSALQLFCHQEGVKGVNISELMKNLDILGDNGNLRNEEQVAVIQAGTVLALCEKWLKQIEGTEAALTQKMMDLEKEKDLFSRQKGYLEQELDYRKEALDQAYLKIQDLEATLYNALQQEPGRRASEALSASQREDLQAAVEKVRRQLLRQSREFDSQILRERMELLQQAQQKIREMEGKLELQRRQLKELEEKFLFLFLFFSLAFILWP", "length": 824, "header": "tr|A0A9J7HBG7-1|A0A9J7HEH3_CRIGR Computationally mapped isoform of Janus kinase and microtubule-interacting protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Jakmip1 PE=3 SV=1 CANONICAL=A0A9J7HEH3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HC35-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH3/entry#A0A9J7HC35-1", "sequence": { "sequence": "MSKKGRSKGEKPETETDSVQMANEELRAKLTNIQIEFQQEKSKMDEIKGKERVILALEKELGVQAGQTQRLLLQKEALDEQLVQVKEAERHHSSPKRELPPGIGDMAELMGGQDQHMDERDVRRFQLKIAELNSVIRKLEDRNTLLADERNELLKRSRETEVQLKPLVEKNKRMNKKNEDLLHSIQRMEEKLKTLTRENVEMKEKLSAQASLKRHTSLTDLSLTRDEQEIEFLRLQVLEQQHVIDDLSLERERLLRSKRHRGKSLKPPKKHVVETFFGFDEESVDSETLSETSYNTDRTDRTPATPEEDLDETTTREEADLRFCQLTREYQALQRAYALLQEQVGGTLDAEREARTREQLQADLLRCQAKIEDLEKLLVEKGQDSAWVEEKQVLMRTNQDLLEKIYRLEMEENQLKSEMQDAKDQNELLEFRVLELEVRDSLCCKLPNGADILFEPKLKFM", "length": 461, "header": "tr|A0A9J7HC35-1|A0A9J7HEH3_CRIGR Computationally mapped isoform of Janus kinase and microtubule-interacting protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Jakmip1 PE=3 SV=1 CANONICAL=A0A9J7HEH3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HDR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH3/entry#A0A9J7HDR8-1", "sequence": { "sequence": "MSKKGRSKGEKPETETDSVQMANEELRAKLTNIQIEFQQEKSKVGKLRERLQEAKLEREQEQRRHTAYISELKAKLHEEKTKELQALREALIRQHEQEAARTAKIKEGELQRLQATLNVLRDGAADKVKTALLAEAREEARRTFDGERQRLQQEILELKAARKQAEEALSNCMQADKAKAADLRAAYQAHQDEVHRIKRECERDIRRLMDEIKGKERVILALEKELGVQAGQTQRLLLQKEALDEQLVQVKEAERHHSSPKRELPPGIGDMAELMGGQDQHMDERDVRRFQLKIAELNSVIRKLEDRNTLLADERNELLKRSRETEVQLKPLVEKNKRMNKKNEDLLHSIQRMEEKLKTLTRENVEMKEKLSAQASLKRHTSLTDLSLTRDEQEIEFLRLQVLEQQHVIDDLSLERERLLRSKRHRGKSLKPPKKHVVETFFGFDEESVDSETLSETSYNTDRTDRTPATPEEDLDETTTREEADLRFCQLTREYQALQRAYALLQEQVGGTLDAEREARTREQLQADLLRCQAKIEDLEKLLVEKGQDSAWVEEKQVLMRTNQDLLEKIYRLEMEENQLKSEMQDAKDQNELLEFRVLELEERERRSPAFNLQITTFPENNSSALQLFCHQEGVKGVNISELMKNLDILGDNGNLRNEEQVAVIQAGTVLALCEKWLKQIEGTEAALTQKMMDLEKEKDLFSRQKGYLEQELDYRKEALDQAYLKIQDLEATLYNALQQEPGRRASEALSASQREDLQAAVEKVRRQLLRQSREFDSQILRERMELLQQAQQKIREMEGKLELQRRQLKELEEKFLFLFLFFSLAFILWP", "length": 831, "header": "tr|A0A9J7HDR8-1|A0A9J7HDR8_CRIGR Computationally mapped isoform of Janus kinase and microtubule-interacting protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Jakmip1 PE=3 SV=1 CANONICAL=A0A9J7HEH3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HEH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH3/entry#A0A9J7HEH3-1", "sequence": { "sequence": "MSKKGRSKGEKPETETDSVQMANEELRAKLTNIQIEFQQEKSKVGKLRERLQEAKLEREQEQRRHTAYISELKAKLHEEKTKELQALREALIRQHEQEAARTAKIKEGELQRLQATLNVLRDGAADKVKTALLAEAREEARRTFDGERQRLQQEILELKAARKQAEEALSNCMQADKAKAADLRAAYQAHQDEVHRIKRECERDIRRLMDEIKGKERVILALEKELGVQAGQTQRLLLQKEALDEQLVQVKEAERHHSSPKRELPPGIGDMAELMGGQDQHMDERDVRRFQLKIAELNSVIRKLEDRNTLLADERNELLKRSRETEVQLKPLVEKNKRMNKKNEDLLHSIQRMEEKLKTLTRENVEMKEKLSAQASLKRHTSLTDLSLTRDEQEIEFLRLQVLEQQHVIDDLSLERERLLRSKRHRGKSLKPPKKHVVETFFGFDEESVDSETLSETSYNTDRTDRTPATPEEDLDETTTREEADLRFCQLTREYQALQRAYALLQEQVGGTLDAEREARTREQLQADLLRCQAKIEDLEKLLVEKGQDSAWVEEKQVLMRTNQDLLEKIYRLEMEENQLKSEMQDAKDQNELLEFRVLELEERERRSPAFNLQITTFPENNSSALQLFCHQEGVKGVNISELMKNLDILGDNGNLRNEEQVAVIQAGTVLALCEKWLKQIEGTEAALTQKMMDLEKEKDLFSRQKGYLEQELDYRKEALDQAYLVGPEKIQDLEATLYNALQQEPGRRASEALSASQREDLQAAVEKVRRQLLRQSREFDSQILRERMELLQQAQQKIREMEGKLELQRRQLKELEEKFLFLFLFFSLAFILWP", "length": 835, "header": "tr|A0A9J7HEH3-1|A0A9J7HEH3_CRIGR Isoform 1 of Janus kinase and microtubule-interacting protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Jakmip1 PE=3 SV=1 CANONICAL=A0A9J7HEH3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HFM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH3/entry#A0A9J7HFM8-1", "sequence": { "sequence": "MSKKGRSKGEKPETETDSVQMANEELRAKLTNIQIEFQQEKSKVGKLRERLQEAKLEREQEQRRHTAYISELKAKLHEEKTKELQALREALIRQHEQEAARTAKIKEGELQRLQATLNVLRDGAADKVKTALLAEAREEARRTFDGERQRLQQEILELKAARKQAEEALSNCMQADKAKAADLRAAYQAHQDEVHRIKRECERDIRRLMDEIKGKERVILALEKELGVQAGQTQRLLLQKEALDEQLVQVKEAERHHSSPKRELPPGIGDMDQHMDERDVRRFQLKIAELNSVIRKLEDRNTLLADERNELLKRSRETEVQLKPLVEKNKRMNKKNEDLLHSIQRMEEKLKTLTRENVEMKEKLSAQASLKRHTSLTDLSLTRDEQEIEFLRLQVLEQQHVIDDLSLERERLLRSKRHRGKSLKPPKKHVVETFFGFDEESVDSETLSETSYNTDRTDRTPATPEEDLDETTTREEADLRFCQLTREYQALQRAYALLQEQVGGTLDAEREARTREQLQADLLRCQAKIEDLEKLLVEKGQIYRLEMEENQLKSEMQDAKDQNELLEFRVLELEERERRSPAFNLQITTFPENNSSALQLFCHQEGVKGVNISELMKNLDILGDNGNLRNEEQVAVIQAGTVLALCEKWLKQIEGTEAALTQKMMDLEKEKDLFSRQKGYLEQELDYRKEALDQAYLKIQDLEATLYNALQQEPGRRASEALSASQREDLQAAVEKVRRQLLRQSREFDSQILRERMELLQQAQQKIREMEGKLELQRRQLKELEEKFLFLFLFFSLAFILWP", "length": 803, "header": "tr|A0A9J7HFM8-1|A0A9J7HFM8_CRIGR Computationally mapped isoform of Janus kinase and microtubule-interacting protein 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Jakmip1 PE=3 SV=1 CANONICAL=A0A9J7HEH3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBG7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBG7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBG7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBG7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771253", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771253", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH3" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH3" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH3" } ], "pmid": "" }, { "name": "GABA receptor binding", "id": "GO:0050811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050811", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 621, "end_pos": 623, "annotation": "n_glycosylation_sequon" }, { "start_pos": 622, "end_pos": 624, "annotation": "n_glycosylation_sequon" }, { "start_pos": 639, "end_pos": 641, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HEH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH3" }, { "id": "PF16034", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16034" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Janus kinase and microtubule-interacting protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 415, "end_pos": 612, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 621, "end_pos": 623 }, { "start_pos": 622, "end_pos": 624 }, { "start_pos": 639, "end_pos": 641 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HCJ8-1", "uniprot_ac": "A0A9J7HCJ8", "uniprot_id": "A0A9J7HCJ8_CRIGR", "mass": { "chemical_mass": 54443.0, "monoisotopic_mass": 54443.0 }, "refseq": { "ac": "XP_035309090", "name": "serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309090" }, "gene_names": [ { "name": "Ppp3cb", "type": "recommended", "evidence": [ { "id": "A0A9J7HCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" } ] }, { "name": "Ppp3cb", "type": "synonym", "evidence": [ { "id": "XP_035309090", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309090" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein phosphatase", "type": "recommended", "evidence": [ { "id": "A0A9J7HCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "A0A9J7HCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035309090", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309090" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309090", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309090" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ppp3cb", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8", "locus": {} } ], "crossref": [ { "id": "A0A9J7HCJ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HCJ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07416", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07416", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764987", "url": "https://www.ncbi.nlm.nih.gov/gene/100764987", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764987", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764987", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HBJ4", "url": "https://www.orthodb.org/?gene=A0A9J7HBJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7HCJ8", "url": "https://www.orthodb.org/?gene=A0A9J7HCJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45673", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45673", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00149", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00149", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309090", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309090", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HBJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDY8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K4K3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4K3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K4K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4K3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEN9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHSAQ", "length": 480, "header": "tr|A0A9J7HCJ8-1|A0A9J7HCJ8_CRIGR Isoform 1 of Serine/threonine-protein phosphatase OS=Cricetulus griseus OX=10029 GN=Ppp3cb PE=3 SV=1 CANONICAL=A0A9J7HCJ8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HBJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8/entry#A0A9J7HBJ4-1", "sequence": { "sequence": "MDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHSAQ", "length": 469, "header": "tr|A0A9J7HBJ4-1|A0A9J7HCJ8_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase OS=Cricetulus griseus OX=10029 GN=Ppp3cb PE=3 SV=1 CANONICAL=A0A9J7HCJ8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HCJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8/entry#A0A9J7HCJ8-1", "sequence": { "sequence": "MDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHSAQ", "length": 480, "header": "tr|A0A9J7HCJ8-1|A0A9J7HCJ8_CRIGR Isoform 1 of Serine/threonine-protein phosphatase OS=Cricetulus griseus OX=10029 GN=Ppp3cb PE=3 SV=1 CANONICAL=A0A9J7HCJ8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HDY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8/entry#A0A9J7HDY8-1", "sequence": { "sequence": "MDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHSAQ", "length": 478, "header": "tr|A0A9J7HDY8-1|A0A9J7HDY8_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase OS=Cricetulus griseus OX=10029 GN=Ppp3cb PE=3 SV=1 CANONICAL=A0A9J7HCJ8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K4K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8/entry#A0A9J7K4K3-1", "sequence": { "sequence": "MDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHSAQ", "length": 470, "header": "tr|A0A9J7K4K3-1|A0A9J7HCJ8_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase OS=Cricetulus griseus OX=10029 GN=Ppp3cb PE=3 SV=1 CANONICAL=A0A9J7HCJ8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KCH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8/entry#A0A9J7KCH9-1", "sequence": { "sequence": "MDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHSAQ", "length": 479, "header": "tr|A0A9J7KCH9-1|A0A9J7HCJ8_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase OS=Cricetulus griseus OX=10029 GN=Ppp3cb PE=3 SV=1 CANONICAL=A0A9J7HCJ8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KEN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8/entry#A0A9J7KEN9-1", "sequence": { "sequence": "MDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSVCMQPEAPSFNLETTLNCREGLKDSSFAEGTICS", "length": 445, "header": "tr|A0A9J7KEN9-1|A0A9J7HCJ8_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase OS=Cricetulus griseus OX=10029 GN=Ppp3cb PE=3 SV=1 CANONICAL=A0A9J7HCJ8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K4K3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4K3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K4K3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4K3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764987", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764987", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "calcineurin-mediated signaling", "id": "GO:0097720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097720", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin-dependent protein phosphatase activity", "id": "GO:0033192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033192", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GV48-1", "G3GWQ6-1", "G3H060-1", "G3H9Q0-1", "G3H7Z6-1", "G3I157-1", "G3HCQ6-1", "A0A8C2MA30-1", "G3HMJ7-1", "G3I434-1", "G3H622-1", "G3HKY7-1", "G3GRD1-1", "G3I4H5-1", "G3H8H2-1", "A0A9J7F890-1", "A0A8C2MW37-1", "A0A061I6V7-1", "A0A9J7GBP5-1", "A0A9J7JFN8-1", "A0A9J7G7W0-1", "A0A9J7GE78-1", "A0A061HVT3-1", "A0A061HX98-1", "A0A3L7HX32-1", "A0A8C2LYQ8-1", "A0A8C2M5N0-1", "A0A9J7JBH1-1", "A0A9J7EY47-1", "A0A8C2LGL9-1", "A0A8C2LVB9-1", "A0A8C2QH88-1", "A0A9J7F130-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FXD0-1", "A0A9J7G243-1", "A0A9J7GEM4-1", "A0A9J7G1B8-1", "A0A9J7K1J8-1", "A0A9J7K5S1-1", "A0A9J7EZL1-1", "A0A8C2QCP2-1", "A0A8C2LTP5-1", "A0A8C2N2E5-1", "A0A8C2QBZ1-1", "A0A3L7HBF4-1", "A0A9J7GK96-1", "A0A8C2LI03-1", "A0A9J7G0U7-1", "A0A9J7GD33-1", "A0A9J7H9S5-1", "A0A9J7HCJ8-1", "A0A9J7GJY7-1", "A0A9J7JYW1-1", "A0A3L7I513-1", "A0A9J7FKB3-1", "A0A8C2LGY1-1", "A0A3L7HEM4-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GV48-1", "G3GWQ6-1", "G3H060-1", "G3H9Q0-1", "G3H622-1", "G3HKY7-1", "G3H7Z6-1", "G3I157-1", "G3HCQ6-1", "A0A8C2MA30-1", "G3HMJ7-1", "A0A8C2MF90-1", "A0A9J7GX39-1", "G3I434-1", "G3GRD1-1", "G3I4H5-1", "G3H8H2-1", "A0A9J7F890-1", "A0A8C2MW37-1", "A0A061I6V7-1", "A0A9J7GBP5-1", "A0A9J7JFN8-1", "A0A9J7G7W0-1", "A0A9J7GE78-1", "A0A061HX98-1", "A0A3L7HEJ5-1", "A0A3L7HX32-1", "A0A8C2LYQ8-1", "A0A8C2M5N0-1", "A0A9J7JBH1-1", "A0A8C2ME51-1", "A0A8C2MTQ0-1", "A0A3L7IJ01-1", "A0A9J7EY47-1", "A0A8C2LGL9-1", "A0A8C2LVB9-1", "A0A8C2QH88-1", "A0A9J7F130-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FXD0-1", "A0A9J7G243-1", "A0A9J7GEM4-1", "A0A9J7G1B8-1", "A0A9J7K1J8-1", "A0A9J7K5S1-1", "A0A9J7EZL1-1", "A0A9J7F6Q7-1", "A0A8C2N2E5-1", "A0A8C2LTP5-1", "A0A8C2QBZ1-1", "A0A8C2QCP2-1", "A0A3L7HBF4-1", "A0A3L7HC66-1", "A0A9J7GK96-1", "A0A8C2LI03-1", "A0A9J7G0U7-1", "A0A9J7GD33-1", "A0A9J7H9S5-1", "A0A9J7HCJ8-1", "A0A9J7GJY7-1", "A0A9J7JXQ8-1", "A0A9J7JYW1-1", "A0A9J7FKB3-1", "A0A8C2LGY1-1", "A0A3L7HEM4-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HVT3", "gene_name": "Ppm1k", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.52", "activity": "O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + H2O = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.52", "activity": "", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] } ] }, { "uniprot_ac": "A0A061HX98", "gene_name": "Dusp9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] } ] }, { "uniprot_ac": "A0A061I6V7", "gene_name": "Pgam5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061I6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6V7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061I6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6V7" } ] } ] }, { "uniprot_ac": "A0A3L7HBF4", "gene_name": "Cpped1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBF4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBF4" } ] } ] }, { "uniprot_ac": "A0A3L7HC66", "gene_name": "Ppp6c", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HC66" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HC66" } ] } ] }, { "uniprot_ac": "A0A3L7HEJ5", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = 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"https://www.uniprot.org/uniprotkb/A0A3L7HEM4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEM4" } ] } ] }, { "uniprot_ac": "A0A3L7HX32", "gene_name": "Dusp8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] } ] }, { "uniprot_ac": "A0A3L7I513", "gene_name": "Pdxp", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] } ] }, { "uniprot_ac": "A0A3L7IJ01", "gene_name": 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H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LTP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTP5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LTP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTP5" } ] } ] }, { "uniprot_ac": "A0A8C2LVB9", "gene_name": "Dusp22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] } ] }, { "uniprot_ac": "A0A8C2LYQ8", "gene_name": "Ppm1l", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYQ8" } ] } ] }, { "uniprot_ac": "A0A8C2M5N0", "gene_name": "Ppp1cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2M5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5N0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2M5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5N0" } ] } ] }, { "uniprot_ac": "A0A8C2MA30", "gene_name": "Phlpp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MA30" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MA30" } ] } ] }, { "uniprot_ac": "A0A8C2ME51", "gene_name": "Ppm1g", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2ME51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ME51" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ 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"O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] } ] }, { "uniprot_ac": "A0A8C2QH88", "gene_name": "Dusp12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": 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"O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] } ] }, { "uniprot_ac": "A0A9J7EZL1", "gene_name": "LOC113830718", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] } ] }, { "uniprot_ac": "A0A9J7F130", "gene_name": "LOC100769947", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F130" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F130" } ] } ] }, { "uniprot_ac": "A0A9J7F6Q7", "gene_name": "LOC103164195", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F6Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6Q7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F6Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6Q7" } ] } ] }, { "uniprot_ac": "A0A9J7F890", "gene_name": "Ctdsp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F890" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F890" } ] } ] }, { "uniprot_ac": "A0A9J7FKB3", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] } ] }, { "uniprot_ac": "A0A9J7FMB0", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] } ] }, { "uniprot_ac": "A0A9J7FWJ6", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FXD0", "gene_name": "Ppm1f", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXD0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXD0" } ] } ] }, { "uniprot_ac": "A0A9J7G0U7", "gene_name": "Pptc7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ] } ] }, { "uniprot_ac": "A0A9J7G1B8", "gene_name": "Phlpp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B8" } ] } ] }, { "uniprot_ac": "A0A9J7G243", "gene_name": "Ppm1a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G243" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G243" } ] } ] }, { "uniprot_ac": "A0A9J7G7W0", "gene_name": "Ptpmt1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.27", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] } ] }, { "uniprot_ac": "A0A9J7GBP5", "gene_name": "Rpap2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GBP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GBP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP5" } ] } ] }, { "uniprot_ac": "A0A9J7GD33", "gene_name": "Ublcp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GD33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GD33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ] } ] }, { "uniprot_ac": "A0A9J7GE78", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] } ] }, { "uniprot_ac": "A0A9J7GEM4", "gene_name": "Ppm1e", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEM4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEM4" } ] } ] }, { "uniprot_ac": "A0A9J7GJY7", "gene_name": "Ppef1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJY7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJY7" } ] } ] }, { "uniprot_ac": "A0A9J7GK96", "gene_name": "Ppm1n", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK96" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK96" } ] } ] }, { "uniprot_ac": "A0A9J7GX39", "gene_name": "Ssh3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GX39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX39" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GX39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX39" } ] } ] }, { "uniprot_ac": "A0A9J7H9S5", "gene_name": "LOC100752571", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7H9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5" } ] } ] }, { "uniprot_ac": "A0A9J7HCJ8", "gene_name": "Ppp3cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7HCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7HCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JBH1", "gene_name": "Cdc14a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] } ] }, { "uniprot_ac": "A0A9J7JFN8", "gene_name": "Epm2a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] } ] }, { "uniprot_ac": "A0A9J7JXQ8", "gene_name": "Ppp2ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXQ8" } ] } ] }, { "uniprot_ac": "A0A9J7JYW1", "gene_name": "Ctdnep1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JYW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYW1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JYW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYW1" } ] } ] }, { "uniprot_ac": "A0A9J7K1J8", "gene_name": "LOC100761879", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7K1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1J8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7K1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1J8" } ] } ] }, { "uniprot_ac": "A0A9J7K5S1", "gene_name": "Ilkap", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7K5S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7K5S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S1" } ] } ] }, { "uniprot_ac": "G3GRD1", "gene_name": "Dusp10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] } ] }, { "uniprot_ac": "G3GV48", "gene_name": "Ppm1b", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3GV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GV48" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3GV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GV48" } ] } ] }, { "uniprot_ac": "G3GWQ6", "gene_name": "Dusp29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] } ] }, { "uniprot_ac": "G3H060", "gene_name": "Dusp26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3H060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H060" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3H060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H060" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3H060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H060" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3H060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H060" } ] } ] }, { "uniprot_ac": "G3H622", "gene_name": "Dusp4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3H622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H622" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3H622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H622" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3H622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H622" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3H622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H622" } ] } ] }, { "uniprot_ac": "G3H7Z6", "gene_name": "Dusp23", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3H7Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H7Z6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3H7Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H7Z6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3H7Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H7Z6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3H7Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H7Z6" } ] } ] }, { "uniprot_ac": "G3H8H2", "gene_name": "Dusp19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3H8H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8H2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3H8H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8H2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3H8H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8H2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3H8H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8H2" } ] } ] }, { "uniprot_ac": "G3H9Q0", "gene_name": "Dusp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3H9Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H9Q0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3H9Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H9Q0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3H9Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H9Q0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3H9Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H9Q0" } ] } ] }, { "uniprot_ac": "G3HCQ6", "gene_name": "Ctdp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3HCQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCQ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3HCQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCQ6" } ] } ] }, { "uniprot_ac": "G3HKY7", "gene_name": "Dusp6", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3HKY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HKY7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3HKY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HKY7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3HKY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HKY7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3HKY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HKY7" } ] } ] }, { "uniprot_ac": "G3HMJ7", "gene_name": "LOC100769403", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3HMJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMJ7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3HMJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMJ7" } ] } ] }, { "uniprot_ac": "G3I157", "gene_name": "Dusp18", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3I157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I157" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3I157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I157" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3I157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I157" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3I157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I157" } ] } ] }, { "uniprot_ac": "G3I434", "gene_name": "Ssu72", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3I434", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I434" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3I434", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I434" } ] } ] }, { "uniprot_ac": "G3I4H5", "gene_name": "Ppp4c", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3I4H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I4H5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3I4H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I4H5" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" }, { "id": "PS00125", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00125" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serine/threonine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 111, "end_pos": 116, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.16", "ec_name": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.16", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16" }, { "id": "3.1.3.16", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.16" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 299, "end_pos": 301 }, { "start_pos": 476, "end_pos": 478 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HC76-1", "uniprot_ac": "A0A9J7HC76", "uniprot_id": "A0A9J7HC76_CRIGR", "mass": { "chemical_mass": 193354.0, "monoisotopic_mass": 193354.0 }, "refseq": { "ac": "XP_035309333", "name": "arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309333" }, "gene_names": [ { "name": "Arap2", "type": "recommended", "evidence": [ { "id": "A0A9J7HC76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC76" } ] }, { "name": "Arap2", "type": "synonym", "evidence": [ { "id": "XP_035309333", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309333" } ] } ], "protein_names": [ { "name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0A9J7HC76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC76/entry#names_and_taxonomy" } ] }, { "name": "Centaurin-delta-1", "type": "synonym", "evidence": [ { "id": "A0A9J7HC76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC76/entry#names_and_taxonomy" } ] }, { "name": "arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035309333", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309333" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309333" } ] }, { "annotation": "Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBT5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBT5#function" }, { "database": "UniProtKB", "id": "ARBA00057622", "url": "https://www.uniprot.org/uniprotkb/ARBA00057622#function" }, { "database": "UniProtKB", "id": "A0A9J7HC76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC76#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC76" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Arap2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC76", "locus": {} } ], "crossref": [ { "id": "cd04385", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04385", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08856", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08856", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09490", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09490", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13253", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13253", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13254", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13254", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13256", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13256", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17227", "url": 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Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751597", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751597", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HC76", "url": "https://www.orthodb.org/?gene=A0A9J7HC76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45899", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45899", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45899:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45899:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309333", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HBT5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC76-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1694, "header": "tr|A0A9J7HBT5-1|A0A9J7HC76_CRIGR Computationally mapped isoform of Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Arap2 PE=4 SV=1 CANONICAL=A0A9J7HC76-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HC76-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC76/entry#A0A9J7HC76-1", "sequence": { "sequence": "MSSVSEVNVDIRDFLMSINLEQYLVHFREFGFYTLKDCASINDSVLHQIGISPTGHRRRILKQLQMIFSKMQDIPIYANVHKTKNGNASKEHQNLPSSSNTTCVEFSDCISVHRPGLTPVEKVTMSTFGVGNCQSPKSHDKLSLPSEEELPQNVDSSQDSLFGSANVKIDSLITQKAVDCTDGEEQTEKVNLISENSRVAFSTNPESLPSVDYPTSETHSGSGTNGLLESSPASPFFQFQGEMVVNDLYVPSSPVHTPMRSRSKLVSRPSRSFLLRHRPVPEIPGSTKAISGSYFRDRRSATTSAGKSLTLKNSKEDNSTSIFPYGETFLFQRLESSKKRSIKNEFWAHEDTVKEDAVTTKNSISTKSSIFDNNKEKVSEDKVEDIWIPREDKNNIPKDSASESEYSTVEECFHSLRRKNSKASKSRTQKAFYLDPFNRHSYPLSSTSGNTDSSTISNAISPYACFYGSSAAKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEREMYSKGIIPLTAISTVRAQGDNKFEIVTTQRTFVFRVEKEEERNDWISILLSALKSPSLTAQLQAAMAPEKCGYLELRGYKAKIFTVLRGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRAVKQSFEIITPYRSFSFTAESEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRICADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMDSPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMTLLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDVHSEGGSSQEAAQSTFLCDFLYQAPATASRVSTEKKLLEETNKKWCVLEGGFLSYYENDKCTTPNGTINISEVICLAVHKEDFYLNTGPIFVFEIYLPSERVFLFGAETSQIQRKWTETIAKHFVPFVAENLTEADYDLIGQLFYKDCHALDQWRKGWFAMDKSSLCFCLQTQETQEERMHLRRLQELTISTMVQNGEKLDVLLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLCKNDVPIIVNSCIAFVTQYGLGCKHIYQKNGDPSHISELLESFKKDARSVKLRAGKHQLEDVTSVLKSFLSDIDDALLTKELYPYWVSTLDIQDEKERTEKYRAFIRTLPGVNRATLAAIIEHLYRVQKCSEINHMNAHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDTQVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIVPSKGDIWATFEVIENEELERPLHYTENVLEQVLQWSSLAEPGSAYLVVKRFLTVDTIKHCRGRCTSFTLESVKEGALKLKEEPSKILSGNKFQDRYIVLRDGHLFLYKDPKSSKHDKMFSLSLMKFYLGVKKKMKPPTSWGLTAYSEKHHWHLCCDSLQAQMEWMASIFIAQHENDIWPPAGKERKRSITKNPKIGGLPLIPIQHERNATQARKNIESARAELEKLWLGEKHDRDFMDPSLRDRASIIAHCLEHKDDKLQNRARKHRSFNCLEDTEAEVPHSLPKGYKGLKTLKKTEDRNSKTTLDADHKLPSKVIEELSVVLQRSRTLPKELLDEQTSQKEIK", "length": 1701, "header": "tr|A0A9J7HC76-1|A0A9J7HC76_CRIGR Isoform 1 of Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Arap2 PE=4 SV=1 CANONICAL=A0A9J7HC76-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBT5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBT5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HBT5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBT5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751597", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751597", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC76" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate binding", "id": "GO:0005547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005547", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC76" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC76" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC76" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC76" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HCG9-1", "uniprot_ac": "A0A9J7HCG9", "uniprot_id": "A0A9J7HCG9_CRIGR", "mass": { "chemical_mass": 21892.0, "monoisotopic_mass": 21892.0 }, "refseq": { "ac": "XP_035309492", "name": "GTPase KRas-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309492" }, "gene_names": [ { "name": "LOC113838653", "type": "recommended", "evidence": [ { "id": "A0A9J7HCG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG9" } ] }, { "name": "LOC113838653", "type": "synonym", "evidence": [ { "id": "XP_035309492", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309492" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A9J7HCG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG9/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A9J7HCG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG9/entry#names_and_taxonomy" } ] }, { "name": "GTPase KRas-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035309492", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309492" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309492", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309492" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113838653", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG9", "locus": {} } ], "crossref": [ { "id": "A0A9J7HCG9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HCG9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04138", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04138", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113838653", "url": "https://www.ncbi.nlm.nih.gov/gene/113838653", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113838653", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838653", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HCG9", "url": "https://www.orthodb.org/?gene=A0A9J7HCG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309492", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309492", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GQZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC34", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC34-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEYKLVVVGPDGVGKTALTIQLIQYHFVDVYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFATNNTKSFEAIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRAVDTNQVQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGRVKIKKMHCNVI", "length": 191, "header": "tr|A0A9J7HCG9-1|A0A9J7HCG9_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113838653 PE=3 SV=1 CANONICAL=A0A9J7HCG9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GQZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG9/entry#A0A9J7GQZ5-1", "sequence": { "sequence": "MTEYKLVVVGPDGVGKTALTIQLIQYHFVDVYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFATNNTKSFEAIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRAVDTNQVQDLAGSYGIPFIETSAKTRQRVEDAFYTLVQEIRNHKEKMSKDGKKKKKKSKTKCIIM", "length": 188, "header": "tr|A0A9J7GQZ5-1|A0A9J7GQZ5_CRIGR Computationally mapped isoform of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113838653 PE=3 SV=1 CANONICAL=A0A9J7HCG9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HC34-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG9/entry#A0A9J7HC34-1", "sequence": { "sequence": "MTEYKLVVVGPDGVGKTALTIQLIQYHFVDVYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFATNNTKSFEAIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRAVDTNQVQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKINGKKKKKKSKTKCIIM", "length": 187, "header": "tr|A0A9J7HC34-1|A0A9J7HCG9_CRIGR Computationally mapped isoform of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113838653 PE=3 SV=1 CANONICAL=A0A9J7HCG9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HCG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG9/entry#A0A9J7HCG9-1", "sequence": { "sequence": "MTEYKLVVVGPDGVGKTALTIQLIQYHFVDVYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFATNNTKSFEAIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRAVDTNQVQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGRVKIKKMHCNVI", "length": 191, "header": "tr|A0A9J7HCG9-1|A0A9J7HCG9_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113838653 PE=3 SV=1 CANONICAL=A0A9J7HCG9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "cge:113838653", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838653", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG9" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRJ8-1", "G3GY22-1", "G3H2D6-1", "G3HID1-1", "A0A9J7FY79-1", "G3IBI0-1", "G3HIM4-1", "G3HLW5-1", "G3I0B0-1", "G3H8L7-1", "G3IMU0-1", "G3HQ45-1", "G3HX83-1", "G3H515-1", "G3HRK4-1", "G3HWS3-1", "G3I185-1", "G3I2E9-1", "G3IHJ9-1", "G3I5Q9-1", "G3H3P1-1", "G3HGA7-1", "A0A9J7K0Q7-1", "G3I8B8-1", "A0A9J7FPY4-1", "A0A9J7JNI7-1", "A0A9J7JTM0-1", "G3HXK0-1", "G3I1T6-1", "A0A8C2M8V3-1", "G3HAT4-1", "G3HBU1-1", "A0A8C2MG78-1", "A0A9J7JFJ5-1", "A0A061I5F7-1", "A0A9J7GMX4-1", "G3H3X0-1", "A0A8C2MG41-1", "A0A8C2MJU2-1", "A0A8C2MKJ3-1", "A0A8C2QMP3-1", "A0A9J7F720-1", "A0A061IFE4-1", "A0A061HZZ7-1", "A0A8C2M6H7-1", "A0A8C2M9W6-1", "A0A9J7H2L4-1", "A0A8C2MH13-1", "A0A8C2MMV7-1", "A0A8C2MPE2-1", "A0A8C2LL65-1", "A0A3L7HXE9-1", "A0A8C2LGZ8-1", "A0A8C2LIB5-1", "A0A8C2LNU7-1", "A0A9J7JYH7-1", "A0A8C2LV21-1", "A0A9J7GDV9-1", "A0A8C2QEY0-1", "A0A9J7FVQ6-1", "A0A9J7K0X9-1", "A0A9J7J7P8-1", "A0A8C2M2X0-1", "A0A8C2MAV7-1", "A0A8C2MQL3-1", "A0A3L7HA69-1", "A0A8C2LLE7-1", "A0A061HWM0-1", "A0A061I5K5-1", "A0A061IH58-1", "A0A061INW8-1", "A0A3L7GXQ2-1", "A0A9J7GN19-1", "A0A3L7HQ44-1", "A0A3L7IA35-1", "A0A3L7IMK5-1", "A0A8C2LIE2-1", "A0A9J7GAZ9-1", "A0A9J7HCG9-1", "A0A9J7HC46-1", "A0A9J7HC79-1", "A0A9J7HCE0-1", "A0A9J7JRE1-1", "A0A9J7GJ78-1", "A0A9J7GKH5-1", "A0A9J7GL76-1", "A0A9J7GLC6-1", "A0A9J7GRC9-1", "A0A9J7GM12-1", "A0A9J7GM74-1", "A0A9J7GP64-1", "A0A9J7GPV5-1", "A0A9J7GQI1-1", "A0A9J7GR82-1", "A0A9J7JY44-1", "A0A9J7JTP9-1", "A0A9J7HGR2-1", "A0A9J7JZZ6-1", "A0A9J7K3I9-1", "A0A9J7K4X6-1", "A0A9J7HD72-1", "A0A9J7KEX2-1", "A0A9J7KFX8-1", "A0A9J7KEY0-1", "A0A9J7KF02-1", "A0A9J7KF14-1", "A0A9J7HFH8-1", "A0A9J7HEY0-1", "A0A9J7KG38-1", "A0A9J7HCJ6-1", "A0A9J7HCM3-1", 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307848", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307848" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCX2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Creb3l4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX2", "locus": {} } ], "crossref": [ { "id": "A0A9J7HCX2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HCX2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14689", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14689", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766300", "url": "https://www.ncbi.nlm.nih.gov/gene/100766300", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766300", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766300", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HCX2", "url": "https://www.orthodb.org/?gene=A0A9J7HCX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45996", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45996", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45996:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45996:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307848", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307848", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IR81", "url": "https://www.uniprot.org/uniprotkb/A0A061IR81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IR81-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IR81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC36", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC36-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCX2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPGCPELLEPPEDIFSTGSFLELGLNCPPSKVLMARLQEQGLGGFSSLKERGLGLQKSEPDDFLNLFIDPNMVYCSETSPGSDSGVSEEPNCPAPQAPGSPALYEVVYEAGALQHTQQEAGPTFGLISIQIDQWSPAFMVPGTCTVSGLSSDAHRHILPRTSTTAPAPPAALLPCQRLFLTDEEKHLLGQEGVTLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKEYIDGLESRVAACSSQNQELQRKVQELERQNTSLVAQVLQLQKLTAQTSSRAAQTSTCVLILLFSLALIILPSFSPFQGQPEARPKAYQPHGVISRNILTHKDMTESPEIPAVKSQLEALPEVPTANDSTKTQLKLVMKARPTGQSRGMLHADEM", "length": 386, "header": "tr|A0A9J7HCX2-1|A0A9J7HCX2_CRIGR Isoform 1 of Cyclic AMP-responsive element-binding protein 3-like protein 4 OS=Cricetulus griseus OX=10029 GN=Creb3l4 PE=3 SV=1 CANONICAL=A0A9J7HCX2-1" }, "isoforms": [ { "isoform_ac": "A0A061IR81-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX2/entry#A0A061IR81-1", "sequence": { "sequence": "MEPGCPELLEPPEDIFSTGSFLELGLNCPPSKGLQKSEPDDFLNLFIDPNMVYCSETSPGSDSGVSEEPNCPAPQAPGSPALYEVVYEAGALQHTQQEAGPTFGLISIQIDQWSPAFMVPGTCTVSGLSSDAHRHILPRTSTTAPAPPAALLPCQRLFLTDEEKHLLGQEGVTLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKEYIDGLESRVAACSSQNQELQRKVQELERQNTSLVAQVLQLQKLTAQTSSRAAQTSTCVLILLFSLALIILPSFSPFQGQPEARPKAYQPHGVISRNILTHKDMTESPEIPAVKSQLEALPEVPTANDSTKTQLKLVMKARPTGQSRGMLHADEM", "length": 364, "header": "tr|A0A061IR81-1|A0A061IR81_CRIGR Computationally mapped isoform of Cyclic AMP-responsive element-binding protein 3-like protein 4 OS=Cricetulus griseus OX=10029 GN=Creb3l4 PE=3 SV=1 CANONICAL=A0A9J7HCX2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HC36-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX2/entry#A0A9J7HC36-1", "sequence": { "sequence": "MEPGCPELLEPPEDIFSTGSFLELGLNCPPSKVLMARLQEQGLQKSEPDDFLNLFIDPNMVYCSETSPGSDSGVSEEPNCPAPQAPGSPALYEVVYEAGALQHTQQEAGPTFGLISIQIDQWSPAFMVPGTCTVSGLSSDAHRHILPRTSTTAPAPPAALLPCQRLFLTDEEKHLLGQEGVTLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKEYIDGLESRVAACSSQNQELQRKVQELERQNTSLVAQVLQLQKLTAQTSSRAAQTSTCVLILLFSLALIILPSFSPFQGQPEARPKAYQPHGVISRNILTHKDMTESPEIPAVKSQLEALPEVPTANDSTKTQLKLVMKARPTGQSRGMLHADEM", "length": 373, "header": "tr|A0A9J7HC36-1|A0A9J7HCX2_CRIGR Computationally mapped isoform of Cyclic AMP-responsive element-binding protein 3-like protein 4 OS=Cricetulus griseus OX=10029 GN=Creb3l4 PE=3 SV=1 CANONICAL=A0A9J7HCX2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HCX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX2/entry#A0A9J7HCX2-1", "sequence": { "sequence": "MEPGCPELLEPPEDIFSTGSFLELGLNCPPSKVLMARLQEQGLGGFSSLKERGLGLQKSEPDDFLNLFIDPNMVYCSETSPGSDSGVSEEPNCPAPQAPGSPALYEVVYEAGALQHTQQEAGPTFGLISIQIDQWSPAFMVPGTCTVSGLSSDAHRHILPRTSTTAPAPPAALLPCQRLFLTDEEKHLLGQEGVTLPSHLPLTKAEERVLKKVRRKIRNKQSAQDSRRRKKEYIDGLESRVAACSSQNQELQRKVQELERQNTSLVAQVLQLQKLTAQTSSRAAQTSTCVLILLFSLALIILPSFSPFQGQPEARPKAYQPHGVISRNILTHKDMTESPEIPAVKSQLEALPEVPTANDSTKTQLKLVMKARPTGQSRGMLHADEM", "length": 386, "header": "tr|A0A9J7HCX2-1|A0A9J7HCX2_CRIGR Isoform 1 of Cyclic AMP-responsive element-binding protein 3-like protein 4 OS=Cricetulus griseus OX=10029 GN=Creb3l4 PE=3 SV=1 CANONICAL=A0A9J7HCX2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC36", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC36" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC36", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC36" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766300", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766300", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCX2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCX2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCX2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX2" } ], "pmid": "" }, { "name": "response to unfolded protein", "id": "GO:0006986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCX2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCX2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCX2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HCX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCX2" }, { "id": "PS50217", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BZIP", "eco_id": "ECO_0000259", "start_pos": 209, "end_pos": 272, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 262, "end_pos": 264 }, { "start_pos": 358, "end_pos": 360 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HC63-1", "uniprot_ac": "A0A9J7HC63", "uniprot_id": "A0A9J7HC63_CRIGR", "mass": { "chemical_mass": 73216.0, "monoisotopic_mass": 73216.0 }, "refseq": { "ac": "XP_035309476", "name": "LOW QUALITY PROTEIN: forkhead box protein P4-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309476" }, "gene_names": [ { "name": "LOC113838365", "type": "recommended", "evidence": [ { "id": "A0A9J7HC63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC63" } ] }, { "name": "LOC113838365", "type": "synonym", "evidence": [ { "id": "XP_035309476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309476" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: forkhead box protein P4-like", "type": "synonym", "evidence": [ { "id": "XP_035309476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309476" }, { "id": "A0A9J7HC63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC63/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309476", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309476" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC63" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113838365", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC63", "locus": {} } ], "crossref": [ { "id": "113838365", "url": "https://www.ncbi.nlm.nih.gov/gene/113838365", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032354", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032354", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113838365", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838365", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HC63", "url": "https://www.orthodb.org/?gene=A0A9J7HC63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45796", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45796", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45796:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45796:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309476", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309476", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HC63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC63-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMEESGSETIRSAPTGQKVGVGSLSGQGDGGSGSWTTGMAAVAGRDGSGRDTTRGADSDGVMSSMELLQFQQQQALQVPRQFLLQQASNLNSPGNKDSKQSASAVQVPMSEAMMSQHMLTPQQMQQNLSPPQLQALLQQQQALMPQQLQEYYKQQQQQLHLQILTQQQAGKQQPREALGNTQLAFQQQLLQMQQLQQQHLLNLKRQGLVDLQPSQASGLLQALPQAAACPSHLPQLWKGQGAPGQPAEDSIRQEGLDLASTAATATWFANAPKVSPPLXHHPLPNRQPTVLTSRRDSSSHEETPSSHPLYGHGECNWPGSETLCEDLGQFIKHLNTEHALDDQSSAQCQEQMQVVQQLEIQLTKESERFQAMKAHVHMGPSEPKPFCQPVTVSSDPFLDGLVHAPASAAAPVTPLQPPGLGSTSLHSGGPARRRSSHEFSSPICSELAQNHDFYKNVAVRPPFTYASLIRQAILESPDRQLTLKEICNWITRMFAFFRGKTDNWKKVVSQNLSMHECFVKVETVKGAVWTVDEQKYQKRRSSRMTGSDDLGPQFWPLNTRYQAALAESNFPFLNSPDMLNPGSACSLLPLSQDDMGAPGEPLPCRGSSSPPRLSPPQXSHQVQVKEEPTEAEEDRQPWPPLGAPNPSTVGTREDRDLEEDLPGEDMS", "length": 667, "header": "tr|A0A9J7HC63-1|A0A9J7HC63_CRIGR Isoform 1 of LOW QUALITY PROTEIN: forkhead box protein P4-like OS=Cricetulus griseus OX=10029 GN=LOC113838365 PE=4 SV=1 CANONICAL=A0A9J7HC63-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HC63-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC63/entry#A0A9J7HC63-1", "sequence": { "sequence": "MMEESGSETIRSAPTGQKVGVGSLSGQGDGGSGSWTTGMAAVAGRDGSGRDTTRGADSDGVMSSMELLQFQQQQALQVPRQFLLQQASNLNSPGNKDSKQSASAVQVPMSEAMMSQHMLTPQQMQQNLSPPQLQALLQQQQALMPQQLQEYYKQQQQQLHLQILTQQQAGKQQPREALGNTQLAFQQQLLQMQQLQQQHLLNLKRQGLVDLQPSQASGLLQALPQAAACPSHLPQLWKGQGAPGQPAEDSIRQEGLDLASTAATATWFANAPKVSPPLXHHPLPNRQPTVLTSRRDSSSHEETPSSHPLYGHGECNWPGSETLCEDLGQFIKHLNTEHALDDQSSAQCQEQMQVVQQLEIQLTKESERFQAMKAHVHMGPSEPKPFCQPVTVSSDPFLDGLVHAPASAAAPVTPLQPPGLGSTSLHSGGPARRRSSHEFSSPICSELAQNHDFYKNVAVRPPFTYASLIRQAILESPDRQLTLKEICNWITRMFAFFRGKTDNWKKVVSQNLSMHECFVKVETVKGAVWTVDEQKYQKRRSSRMTGSDDLGPQFWPLNTRYQAALAESNFPFLNSPDMLNPGSACSLLPLSQDDMGAPGEPLPCRGSSSPPRLSPPQXSHQVQVKEEPTEAEEDRQPWPPLGAPNPSTVGTREDRDLEEDLPGEDMS", "length": 667, "header": "tr|A0A9J7HC63-1|A0A9J7HC63_CRIGR Isoform 1 of LOW QUALITY PROTEIN: forkhead box protein P4-like OS=Cricetulus griseus OX=10029 GN=LOC113838365 PE=4 SV=1 CANONICAL=A0A9J7HC63-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:113838365", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838365", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC63" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC63" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC63" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC63" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC63" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HC63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC63" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fork-head", "eco_id": "ECO_0000259", "start_pos": 460, "end_pos": 534, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 511, "end_pos": 513 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A9J7HC74-1", "uniprot_ac": "A0A9J7HC74", "uniprot_id": "A0A9J7HC74_CRIGR", "mass": { "chemical_mass": 69301.0, "monoisotopic_mass": 69301.0 }, "refseq": { "ac": "XP_035308887", "name": "adhesion G protein-coupled receptor F4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308887" }, "gene_names": [ { "name": "Adgrf4", "type": "recommended", "evidence": [ { "id": "A0A9J7HC74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC74" } ] }, { "name": "Adgrf4", "type": "synonym", "evidence": [ { "id": "XP_035308887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308887" } ] } ], "protein_names": [ { "name": "Adhesion G protein-coupled receptor F4", "type": "synonym", "evidence": [ { "id": "A0A9J7HC74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC74/entry#names_and_taxonomy" } ] }, { "name": "adhesion G protein-coupled receptor F4", "type": "synonym", "evidence": [ { "id": "XP_035308887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308887" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 4% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308887", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308887" } ] }, { "annotation": "Orphan receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC74#function" }, { "database": "UniProtKB", "id": "ARBA00035627", "url": "https://www.uniprot.org/uniprotkb/ARBA00035627#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC74" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Adgrf4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC74", "locus": {} } ], "crossref": [ { "id": "A0A9J7HC74", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HC74", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15994", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15994", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770639", "url": "https://www.ncbi.nlm.nih.gov/gene/100770639", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770639", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770639", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HC74", "url": "https://www.orthodb.org/?gene=A0A9J7HC74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45813", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45813", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45813:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45813:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308887", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308887", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HC74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC74-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC74-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSEPKTPVTAMCARAEQLPGASRSASLAKTGPNTAASLSVASSSLFPMNLIGSKVPPVSIGNIFQGIHKYCPKDYICIVDAVKSSEVTSGNIAFIVELLKNISAGLQTYNGPHGNVTHEKMKNYGKMANHILSKTAISNWAFIPNKNASSDLLESVNSFAKKLQVHSESESIVNELFIQTKGARIYHNTSKNSFNLSMPMDKDTEDVLVLIEIPRHALHKLPSNASQAIGIAFPTLGAILKEVHGPNMNLSKPINSLILSLVLPEELKEIILIFEKINKSQSTSSHCVGWHSEKRQWDESPCKMVLDSTGTVNCHCNYNRTVTSFSILMSSKPVRDTVLSYITFIGISVSIFSLVLCLVVEAVVWSRVVVTEISYMRHVCIVNIAVSLLSANVWFIIGSSANVQEDHKWCVAVTFFNHFFFLSLFFWMLFKGLLIVYGILVVFRRMMKSRMMAIGFAIGYGCPLVIAVITVSVTEPGEGYIRKDACWLNWNQTKALLAFAIPALAIVAVNLLVVLAVAINTQRPLIGSSKSQDMAIVIRISKNVAILTPLLGLTWGFGLVTLLEGTHLVFHIIFALLNAFQGFFILLFGTIMDHKIRDALRMRVSSLKGKSRAAEKASLSPANGSKVLNR", "length": 631, "header": "tr|A0A9J7HC74-1|A0A9J7HC74_CRIGR Isoform 1 of Adhesion G protein-coupled receptor F4 OS=Cricetulus griseus OX=10029 GN=Adgrf4 PE=3 SV=1 CANONICAL=A0A9J7HC74-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HC74-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC74/entry#A0A9J7HC74-1", "sequence": { "sequence": "MRSEPKTPVTAMCARAEQLPGASRSASLAKTGPNTAASLSVASSSLFPMNLIGSKVPPVSIGNIFQGIHKYCPKDYICIVDAVKSSEVTSGNIAFIVELLKNISAGLQTYNGPHGNVTHEKMKNYGKMANHILSKTAISNWAFIPNKNASSDLLESVNSFAKKLQVHSESESIVNELFIQTKGARIYHNTSKNSFNLSMPMDKDTEDVLVLIEIPRHALHKLPSNASQAIGIAFPTLGAILKEVHGPNMNLSKPINSLILSLVLPEELKEIILIFEKINKSQSTSSHCVGWHSEKRQWDESPCKMVLDSTGTVNCHCNYNRTVTSFSILMSSKPVRDTVLSYITFIGISVSIFSLVLCLVVEAVVWSRVVVTEISYMRHVCIVNIAVSLLSANVWFIIGSSANVQEDHKWCVAVTFFNHFFFLSLFFWMLFKGLLIVYGILVVFRRMMKSRMMAIGFAIGYGCPLVIAVITVSVTEPGEGYIRKDACWLNWNQTKALLAFAIPALAIVAVNLLVVLAVAINTQRPLIGSSKSQDMAIVIRISKNVAILTPLLGLTWGFGLVTLLEGTHLVFHIIFALLNAFQGFFILLFGTIMDHKIRDALRMRVSSLKGKSRAAEKASLSPANGSKVLNR", "length": 631, "header": "tr|A0A9J7HC74-1|A0A9J7HC74_CRIGR Isoform 1 of Adhesion G protein-coupled receptor F4 OS=Cricetulus griseus OX=10029 GN=Adgrf4 PE=3 SV=1 CANONICAL=A0A9J7HC74-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC74" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A9J7HC92-1", "uniprot_ac": "A0A9J7HC92", "uniprot_id": "A0A9J7HC92_CRIGR", "mass": { "chemical_mass": 73501.0, "monoisotopic_mass": 73501.0 }, "refseq": { "ac": "XP_035309523", "name": "LOW QUALITY PROTEIN: forkhead box protein P4-like isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309523" }, "gene_names": [ { "name": "LOC100755450", "type": "recommended", "evidence": [ { "id": "A0A9J7HC92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC92" } ] }, { "name": "LOC100755450", "type": "synonym", "evidence": [ { "id": "XP_035309523", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309523" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: forkhead box protein P4-like isoform X3", "type": "synonym", "evidence": [ { "id": "XP_035309523", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309523" }, { "id": "A0A9J7HC92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC92/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309523", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309523" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC92" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100755450", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC92", "locus": {} } ], "crossref": [ { "id": "100755450", "url": "https://www.ncbi.nlm.nih.gov/gene/100755450", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032354", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032354", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755450", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755450", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HC92", "url": "https://www.orthodb.org/?gene=A0A9J7HC92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7HFG7", "url": "https://www.orthodb.org/?gene=A0A9J7HFG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45796", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45796", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45796:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45796:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309523", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309523", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC92-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HFG7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HFG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMEESGSETIRSAPTGQKVGMGSLSGQGDGGSGSWTTGMAAVAGRDGSGRDTTRGADSDGEMSSMELLQFQQQQALQVPRQFLLQQASNLNSPGNKDSKQWASAVQVPMSEAMMSQHMLTPQQMQQNLSHPQLQALLQQQQALMPQQLQEYYKQQQQQLHLQILTQQQAGKQQPRETLGNTQLAFQQQLLQMQQLQQQHLLNLQRQGLVDLQPSQASWPLQALPQAAACPTDLPELWKGQGAPGQPAEDSIRQEGLDLASTAATATWFASAPKVSPPLCHHPLPNRQPTVLTPRRDSSSHEETPSSHPLYGHGECNWPGGETLCEDLGQFIKHLNTEHTLDDQSTAQCQEQMQVVQQLEIQLTKESERFQAMKAHVHMGPSEPKPFCQPVTVSSDPFPDGLVHPPAPAAAPVTPLQPPVLGSTSLHSGGPARRRSSHEFGSPIYSELPKYHDYVKNVAVRPPFTYASLIRQAILESPDRQLTLKEICNWITRMFAFFRGKTDNWKKVVSHNLSLHECFVKVETVKGAVWPVDEQKYQKQRSSRMTGSDDLGPQFWPLNTSYQAALAESNFPFLNSPDMLNPGSASSLLPLSQDDMGAPGEPLPCRGSSSPPRLSPPQXSHQVQVKEEPAEAEEDRQPWPPLGAPNPSTVGPREDRDLEEDLPGEDMS", "length": 667, "header": "tr|A0A9J7HC92-1|A0A9J7HC92_CRIGR Isoform 1 of LOW QUALITY PROTEIN: forkhead box protein P4-like isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100755450 PE=4 SV=1 CANONICAL=A0A9J7HC92-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HC92-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC92/entry#A0A9J7HC92-1", "sequence": { "sequence": "MMEESGSETIRSAPTGQKVGMGSLSGQGDGGSGSWTTGMAAVAGRDGSGRDTTRGADSDGEMSSMELLQFQQQQALQVPRQFLLQQASNLNSPGNKDSKQWASAVQVPMSEAMMSQHMLTPQQMQQNLSHPQLQALLQQQQALMPQQLQEYYKQQQQQLHLQILTQQQAGKQQPRETLGNTQLAFQQQLLQMQQLQQQHLLNLQRQGLVDLQPSQASWPLQALPQAAACPTDLPELWKGQGAPGQPAEDSIRQEGLDLASTAATATWFASAPKVSPPLCHHPLPNRQPTVLTPRRDSSSHEETPSSHPLYGHGECNWPGGETLCEDLGQFIKHLNTEHTLDDQSTAQCQEQMQVVQQLEIQLTKESERFQAMKAHVHMGPSEPKPFCQPVTVSSDPFPDGLVHPPAPAAAPVTPLQPPVLGSTSLHSGGPARRRSSHEFGSPIYSELPKYHDYVKNVAVRPPFTYASLIRQAILESPDRQLTLKEICNWITRMFAFFRGKTDNWKKVVSHNLSLHECFVKVETVKGAVWPVDEQKYQKQRSSRMTGSDDLGPQFWPLNTSYQAALAESNFPFLNSPDMLNPGSASSLLPLSQDDMGAPGEPLPCRGSSSPPRLSPPQXSHQVQVKEEPAEAEEDRQPWPPLGAPNPSTVGPREDRDLEEDLPGEDMS", "length": 667, "header": "tr|A0A9J7HC92-1|A0A9J7HC92_CRIGR Isoform 1 of LOW QUALITY PROTEIN: forkhead box protein P4-like isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100755450 PE=4 SV=1 CANONICAL=A0A9J7HC92-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HFG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC92/entry#A0A9J7HFG7-1", "sequence": { "sequence": "MMEESGSETIMSAPTGQKVGVGSLSGQGDGGSGSWTTGMAAVAGRDSSGRDTTRGADSDGEMSSMELLQFQQQQALQVPRQFLLQQASNLNSPGNKDSKQSASAVQVPMSEAMMSQHMLTPQQMQQNLSXPQLQALLQQQQALMPQQLQEYYKQQQQQLHLQILTQQQAGKQQPREALGNTQLAFQQQLLQMQQLQQQHLLNLQRQGLVDLQPSQASWPLQALPQAAACPTDLPQLWKGQGAPGQPAEDSFRQEGLDLASTAATATWFASAPKVSPPLCHHPLPNRQPTVLTPRRDSSSHEETPSSHPLYGQGECNWPGGETLCEDLGQFIKHLNTEHALDDQSTAQFQEQMQVVQQLEIQLTKENEGFQAMKAHVHMGPSEPKPFCQPVTVSSDPFPDGLVHPPAPAAAPVTSLQPPGLGSTSLRSGGPACRRSSHEFGSPIYSELPKYHDYFKNVAVRPPFTYASLICQAILESPDRQLTLKEICNWITRMFAFFRGKTDNWKKVVSQNLRLHECFVKVETVKGAVWTVEEQKYQKRRSSRMTESDDLGPQFWPLNTSYQAALAESNFPFLNSPDMLNPGSASSLLPLSQDDMGAPGEPLPCRGSSSPPRLSPPQXSHQVQVKEEPAEAEEDRQPWPPLGAPNPSTVGPREDRDLEEDLPGEDMS", "length": 667, "header": "tr|A0A9J7HFG7-1|A0A9J7HFG7_CRIGR Computationally mapped isoform of LOW QUALITY PROTEIN: forkhead box protein P4-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100755450 PE=4 SV=1 CANONICAL=A0A9J7HC92-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:100755450", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755450", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC92" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC92" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC92" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC92" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" }, { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HC92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC92" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fork-head", "eco_id": "ECO_0000259", "start_pos": 460, "end_pos": 534, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 511, "end_pos": 513 }, { "start_pos": 558, "end_pos": 560 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A9J7HC99-1", "uniprot_ac": "A0A9J7HC99", "uniprot_id": "A0A9J7HC99_CRIGR", "mass": { "chemical_mass": 21936.0, "monoisotopic_mass": 21936.0 }, "refseq": { "ac": "XP_035308918", "name": "LOW QUALITY PROTEIN: neuropeptide-like protein C4orf48 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308918" }, "gene_names": [ { "name": "CUNH4orf48", "type": "recommended", "evidence": [ { "id": "A0A9J7HC99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC99" } ] }, { "name": "CUNH4orf48", "type": "synonym", "evidence": [ { "id": "XP_035308918", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308918" } ] } ], "protein_names": [ { "name": "NELL2-interacting cell ontogeny regulator 1", "type": "recommended", "evidence": [ { "id": "A0A9J7HC99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC99/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: neuropeptide-like protein C4orf48 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035308918", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308918" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 38% of CDS bases internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308918", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308918" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC99" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "CUNH4orf48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC99", "locus": {} } ], "crossref": [ { "id": "100769685", "url": "https://www.ncbi.nlm.nih.gov/gene/100769685", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769685", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769685", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HC99", "url": "https://www.orthodb.org/?gene=A0A9J7HC99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35451", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35451", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35451:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35451:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15161", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15161", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308918", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308918", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HC99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HC99-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSRRPPTRVGPGETEIKFSSNQQLIPVERQRPGRRCWPSTEQASRRLGAARARSARDRGVSITTTSGTQAGSAWTHARARAGHGASSRVARAAGRGSREPRXGWAPSSAMAPAPRSWLSPPTLLLLLLLLLSLALLGVRAEPAAGSAVPAQSRPCVDCHAFEFMQRALQDLRKTAYSLDARTETLLLQAERRALCACWPAGR", "length": 203, "header": "tr|A0A9J7HC99-1|A0A9J7HC99_CRIGR Isoform 1 of NELL2-interacting cell ontogeny regulator 1 OS=Cricetulus griseus OX=10029 GN=CUNH4orf48 PE=3 SV=1 CANONICAL=A0A9J7HC99-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HC99-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC99/entry#A0A9J7HC99-1", "sequence": { "sequence": "MLSRRPPTRVGPGETEIKFSSNQQLIPVERQRPGRRCWPSTEQASRRLGAARARSARDRGVSITTTSGTQAGSAWTHARARAGHGASSRVARAAGRGSREPRXGWAPSSAMAPAPRSWLSPPTLLLLLLLLLSLALLGVRAEPAAGSAVPAQSRPCVDCHAFEFMQRALQDLRKTAYSLDARTETLLLQAERRALCACWPAGR", "length": 203, "header": "tr|A0A9J7HC99-1|A0A9J7HC99_CRIGR Isoform 1 of NELL2-interacting cell ontogeny regulator 1 OS=Cricetulus griseus OX=10029 GN=CUNH4orf48 PE=3 SV=1 CANONICAL=A0A9J7HC99-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC99" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC99" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769685", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769685", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC99" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HC99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HC99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HCB0-1", "uniprot_ac": "A0A9J7HCB0", "uniprot_id": "A0A9J7HCB0_CRIGR", "mass": { "chemical_mass": 48225.0, "monoisotopic_mass": 48225.0 }, "refseq": { "ac": "XP_035309612", "name": "zinc finger and SCAN domain-containing protein 4-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309612" }, "gene_names": [ { "name": "LOC113837849", "type": "recommended", "evidence": [ { "id": "A0A9J7HCB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB0" } ] }, { "name": "LOC113837849", "type": "synonym", "evidence": [ { "id": "XP_035309612", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309612" } ] } ], "protein_names": [ { "name": "Zinc finger and SCAN domain-containing protein 4-like", "type": "synonym", "evidence": [ { "id": "A0A9J7HCB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB0/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and SCAN domain-containing protein 4-like", "type": "synonym", "evidence": [ { "id": "XP_035309612", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309612" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 100% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276853.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309612", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309612" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB0#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113837849", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB0", "locus": {} } ], "crossref": [ { "id": "A0A9J7HCB0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HCB0", "database": "AlphaFoldDB", "categories": [] }, { "id": "113837849", "url": "https://www.ncbi.nlm.nih.gov/gene/113837849", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113837849", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837849", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HCB0", "url": "https://www.orthodb.org/?gene=A0A9J7HCB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226:SF88", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226:SF88", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309612", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309612", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HCB0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLQRESLETRSPGNDCGLEKTEFIPTRASPVQFREDNSNSPVSEVNIPPTGNGSCAKQELQYLWEMFTSWLQPEKQTKEQMISQLVMEQFFKTGHYKDKLAMKDKWESSGKNMVKFMENLTDECVEPPKMFHVSMQGEEGLFPGHMSLNEVINLLKEMKSSSTSKQENKRTTLQSPLNKLLPTGHEDSGDGYNNPLNLIKVNTSDRSPGNEMNSLVIIEKYNCPETEERGESDGLSQDFRCSRHHQVSLSGSSSVSVPKDKDQPEVVVPVEQPQSGIITRAEKTGDSQNCETDHTGESVQERSSRVPKTHQCVECLRIFRYPSQLLAHKRRHKKERSFLCKRCPKSFFNQSDLKVHSVIHQAFKPFTCNTCGRSFSHKTNLLAHERIHTGEKPYNCSKCNCNFRQSSTYHRHMRHCHKSH", "length": 422, "header": "tr|A0A9J7HCB0-1|A0A9J7HCB0_CRIGR Isoform 1 of Zinc finger and SCAN domain-containing protein 4-like OS=Cricetulus griseus OX=10029 GN=LOC113837849 PE=3 SV=1 CANONICAL=A0A9J7HCB0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HCB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB0/entry#A0A9J7HCB0-1", "sequence": { "sequence": "MASLQRESLETRSPGNDCGLEKTEFIPTRASPVQFREDNSNSPVSEVNIPPTGNGSCAKQELQYLWEMFTSWLQPEKQTKEQMISQLVMEQFFKTGHYKDKLAMKDKWESSGKNMVKFMENLTDECVEPPKMFHVSMQGEEGLFPGHMSLNEVINLLKEMKSSSTSKQENKRTTLQSPLNKLLPTGHEDSGDGYNNPLNLIKVNTSDRSPGNEMNSLVIIEKYNCPETEERGESDGLSQDFRCSRHHQVSLSGSSSVSVPKDKDQPEVVVPVEQPQSGIITRAEKTGDSQNCETDHTGESVQERSSRVPKTHQCVECLRIFRYPSQLLAHKRRHKKERSFLCKRCPKSFFNQSDLKVHSVIHQAFKPFTCNTCGRSFSHKTNLLAHERIHTGEKPYNCSKCNCNFRQSSTYHRHMRHCHKSH", "length": 422, "header": "tr|A0A9J7HCB0-1|A0A9J7HCB0_CRIGR Isoform 1 of Zinc finger and SCAN domain-containing protein 4-like OS=Cricetulus griseus OX=10029 GN=LOC113837849 PE=3 SV=1 CANONICAL=A0A9J7HCB0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:113837849", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837849", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB0", "url": 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307998", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307998" } ] }, { "annotation": "Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB4#function" }, { "database": "UniProtKB", "id": "ARBA00037665", "url": "https://www.uniprot.org/uniprotkb/ARBA00037665#function" }, { "database": "UniProtKB", "id": "A0A9J7J5Z3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus 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Classification" ] }, { "id": "PTHR22237:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22237:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307998", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307998", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HCB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J5Z3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J5Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METGRSRGSGGAAVSERGGGARAGVCRRQEQAGALAADMDSHCECAAETPAAEPPSGKINKAAFKLFKKRKSGGTMPSIFGVKNKGDGKSAGPTGMVRSRTHDGLAEVLVLEGSKKEEPPGGGDHGGARPNPGPPKAAGPGLASLASSSVAKSHSFFSLLKKNGRSETGKGDSAEASKAGGKQKRGLKGIFSSMRWHRRDKRGKEEEEKAARAAGPGSLVLPGSLTASLECVKEEPPRAARRPDSPGQDAPRHAAGEPEGGEQAPASAERAPARTCLEAASPAGPGDPSARGEDAEGHWRAEKPGAALESGAGEVQAAEDASRTGCGDIIADPEEEAGPSCDKHVPGPGKPVLSKKNPTVVAYQGGGEEMASPDEVDDTYLPEFWDMLSQTEDQGQRPQEGAVKAATASDTKLAPETSNDARCGEVAKDASSSVKHRRLHRIPIEPQQKEEPKHPEKEHQEGVPNSDEGYWDSTTPGPEEDSASSSKKAVIPRDSDSGDALYDLYTEPEGSPAALPVAEDPPCLSRLKPVSPGTITCPLRTPGSLLKDSKIPISIKHLSNLPSSHPVVHQQPARSELPRTKIPVSKVLVRRVSNRGLAGTTIRAAACHDSAKKL", "length": 614, "header": "tr|A0A9J7HCB4-1|A0A9J7HCB4_CRIGR Isoform 1 of APC membrane recruitment protein 2 OS=Cricetulus griseus OX=10029 GN=Amer2 PE=3 SV=1 CANONICAL=A0A9J7HCB4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HCB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB4/entry#A0A9J7HCB4-1", "sequence": { "sequence": "METGRSRGSGGAAVSERGGGARAGVCRRQEQAGALAADMDSHCECAAETPAAEPPSGKINKAAFKLFKKRKSGGTMPSIFGVKNKGDGKSAGPTGMVRSRTHDGLAEVLVLEGSKKEEPPGGGDHGGARPNPGPPKAAGPGLASLASSSVAKSHSFFSLLKKNGRSETGKGDSAEASKAGGKQKRGLKGIFSSMRWHRRDKRGKEEEEKAARAAGPGSLVLPGSLTASLECVKEEPPRAARRPDSPGQDAPRHAAGEPEGGEQAPASAERAPARTCLEAASPAGPGDPSARGEDAEGHWRAEKPGAALESGAGEVQAAEDASRTGCGDIIADPEEEAGPSCDKHVPGPGKPVLSKKNPTVVAYQGGGEEMASPDEVDDTYLPEFWDMLSQTEDQGQRPQEGAVKAATASDTKLAPETSNDARCGEVAKDASSSVKHRRLHRIPIEPQQKEEPKHPEKEHQEGVPNSDEGYWDSTTPGPEEDSASSSKKAVIPRDSDSGDALYDLYTEPEGSPAALPVAEDPPCLSRLKPVSPGTITCPLRTPGSLLKDSKIPISIKHLSNLPSSHPVVHQQPARSELPRTKIPVSKVLVRRVSNRGLAGTTIRAAACHDSAKKL", "length": 614, "header": "tr|A0A9J7HCB4-1|A0A9J7HCB4_CRIGR Isoform 1 of APC membrane recruitment protein 2 OS=Cricetulus griseus OX=10029 GN=Amer2 PE=3 SV=1 CANONICAL=A0A9J7HCB4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J5Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB4/entry#A0A9J7J5Z3-1", "sequence": { "sequence": "METGRSRGSGGAAVSERGGGARAGVCRRQEQAGALAADMDSHCECAAETPAAEPPSGKINKAAFKLFKKRKSGGTMPSIFGVKNKGDGKSAGPTGMVRSRTHDGLAEVLVLEGSKKEEPPGGGDHGGARPNPGPPKAAGPGLASLASSSVAKSHSFFSLLKKNGRSETGKGDSAEASKAGGKQKRGLKGIFSSMRWHRRDKRGKEEEEKAARAAGPGSLVLPGSLTASLECVKEEPPRAARRPDSPGQDAPRHAAGCGDIIADPEEEAGPSCDKHVPGPGKPVLSKKNPTVVAYQGGGEEMASPDEVDDTYLPEFWDMLSQTEDQGQRPQEGAVKAATASDTKLAPETSNDARCGEVAKDASSSVKHRRLHRIPIEPQQKEEPKHPEKEHQEGVPNSDEGYWDSTTPGPEEDSASSSKKAVIPRDSDSGDALYDLYTEPEGSPAALPVAEDPPCLSRLKPVSPGTITCPLRTPGSLLKDSKIPISIKHLSNLPSSHPVVHQQPARSELPRTKIPVSKVLVRRVSNRGLAGTTIRAAACHDSAKKL", "length": 545, "header": "tr|A0A9J7J5Z3-1|A0A9J7J5Z3_CRIGR Computationally mapped isoform of APC membrane recruitment protein 2 OS=Cricetulus griseus OX=10029 GN=Amer2 PE=3 SV=1 CANONICAL=A0A9J7HCB4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766392", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766392", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB4" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB4" } ], "pmid": "" }, { "name": "regulation of canonical Wnt signaling pathway", "id": "GO:0060828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060828", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCB4" } ], "pmid": "" } ] } ] }, 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309352" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309352", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309352" } ] }, { "annotation": "Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC6#function" }, { "database": "UniProtKB", "id": "ARBA00059106", "url": "https://www.uniprot.org/uniprotkb/ARBA00059106#function" }, { "database": "UniProtKB", "id": "A0A9J7HEN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEN4#function" }, { "database": "UniProtKB", "id": "A0A9J7HFE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFE3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFE3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zfyve28", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051118", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051118", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771033", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771033", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HFE3", "url": "https://www.orthodb.org/?gene=A0A9J7HFE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46465:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46465:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309352", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309352", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HCC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HEN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HEN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HFE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HFE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFE3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEECIPQDRAPRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNRELESMAMRPLAKELTRSLEDVRGTLRDQALRDLNTYTEKMREALRHFDVLFAEFELSYVSAMVPVKSPREYYVQQEVIVLFCETVERALDFGYLTQDMIDDYEPALMFTIPRLAIVCGLVVYADGPLNLDRKVEDMSELFRPFHTLLRKIRDLLQALTEEELHTLERSLCVSQDVELPIRADTQAPSALAPTFSTSLPPEEPLSASASNSEAELACSMQYDDQELEELSRMVHRAGDEMSSLLSPPSACQSPAHRPGTEASPRGEASPARARLKSGSDEEERVFFMDDVEVAESPARSESPGDTFELTGSMQSNVQQRGQDSQSGEVGVGAPSLVKEEDWSNNNIEDDKIKLASLVGSTSCSCLDSQLYLDGWEVNTDDAETAEMIAHRTGGMKLSATVIFNPKSHASLDSAVATQEATDRGISPLEPRAEGTGDNSHKLGTAATNCLLHSCVCCGSCGDSREDAVEHLQEKCGPGSIISASNPSVSLAKAGDKEPERLDEAWSSPDVTLPAEDASSGQEPKAPAPNKCLAHTSGPQVDTASRLQGEGEVKRQPELETRNQDPEKSSVVRGDSPREDMAQTEPQHLSGSSSSTAGSCSLDNTRLEVAPAAMPLTPMATREKIRSRFHGSHDLIHRLFVCISGVADQLQTNYASDLRSILKTLFEVMATKPETDDKEKLKKVTQTLRSAALEDCALCQETVSSSELAAKTRDGDFEDPPEWVPDEACGFCTSCKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCYMFHVTPFYSDKTGM", "length": 840, "header": "tr|A0A9J7HFE3-1|A0A9J7HFE3_CRIGR Isoform 1 of Lateral signaling target protein 2 homolog OS=Cricetulus griseus OX=10029 GN=Zfyve28 PE=3 SV=1 CANONICAL=A0A9J7HFE3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HCC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFE3/entry#A0A9J7HCC6-1", "sequence": { "sequence": "MEECIPQDRAPRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNRELESMAMRPLAKELTRSLEDVRGTLRDQALRDLNTYTEKMREALRHFDVLFAEFELSYVSAMVPVKSPREYYVQQEVIVLFCETVESGLVVYADGPLNLDRKVEDMSELFRPFHTLLRKIRDLLQALTEEELHTLERSLCVSQDVELPIRADTQAPSALAPTFSTSLPPEEPLSASASNSEAELACSMQYDDQELEELSRMVHRAGDEMSSLLSPPSACQSPAHRPGTEASPRGEASPARARLKSGSDEEERVFFMDDVEVAESPARSESPGDTFELTGSMQSNVQQRGQDSQSGEVGVGAPSLVKEEDWSNNNIEDDKIKLASLVGSTSCSCLDSQLYLDGWEVNTDDAETAEMIAHRTGGMKLSATVIFNPKSHASLDSAVATQEATDRGISPLEPRAEGTGDNSHKLGTAATNCLLHSCVCCGSCGDSREDAVEHLQEKCGPGSIISASNPSVSLAKAGDKEPERLDEAWSSPDVTLPAEDASSGQEPKAPAPNKCLAHTSGPQVDTASRLQGEGEVKRQPELETRNQDPEKSSVVRGDSPREDMAQTEPQHLSGSSSSTAGSCSLDNTRLEVAPAAMPLTPMATREKIRSRFHGSHDLIHRLFVCISGVADQLQTNYASDLRSILKTLFEVMATKPETDDKEKLKKVTQTLRSAALEDCALCQETVSSSELAAKTRDGDFEDPPEWVPDEACGFCTSCKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCYMFHVTPFYSDKTGM", "length": 810, "header": "tr|A0A9J7HCC6-1|A0A9J7HFE3_CRIGR Computationally mapped isoform of Lateral signaling target protein 2 homolog OS=Cricetulus griseus OX=10029 GN=Zfyve28 PE=3 SV=1 CANONICAL=A0A9J7HFE3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HEN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFE3/entry#A0A9J7HEN4-1", "sequence": { "sequence": "MEECIPQDRAPRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNRELESMAMRPLAKELTRSLEDVRGTLRDQALRDLNTYTEKMREALRHFDVLFAEFELSYVSAMVPVKSPREYYVQQEVIVLFCETVERALDFGYLTQDMIDDYEPALMFTIPRLAIVCGLVVYADGPLNLDRKVEDMSELFRPFHTLLRKIRDLLQALTEEELHTLERSLCVSQDVELPIRADTQAPSALAPTFSTSLPPEEPLSASASNSEAELACSMQYDDQELEELSRMVHRAGDEMSSLLSPPSACQSPAHRPGTEASPRGEASPARARLKSGSDEEERVFFMDDVEVAESPARSESPGDTFELTGSMQSNVQQRGQDSQSGEVGVGAPSLVKEEDWSNNNIEDDKIKLASLVGSTSCSCLDSQLYLDGWEVNTDDAETAEMIAHRTGGMKLSATVIFNPKSHASLDSAVATQEATDRGISPLEPRAEGTGDNSHKLGTAATNCLLHSCVCCGSCGDSREDAVEHLQEKCGPGSIISASNPSVSLAKAGDKEPERLDEAWSSPDVTLPAEDASSGQEPKAPAPNKCLAHTSGPQVDTASRLQGEGEVKRQPELETRNQDPEKSSVVRGDSPREDMAQTEPQHLSGSSSTAGSCSLDNTRLEVAPAAMPLTPMATREKIRSRFHGSHDLIHRLFVCISGVADQLQTNYASDLRSILKTLFEVMATKPETDDKEKLKKVTQTLRSAALEDCALCQETVSSSELAAKTRDGDFEDPPEWVPDEACGFCTSCKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCYMFHVTPFYSDKTGM", "length": 839, "header": "tr|A0A9J7HEN4-1|A0A9J7HEN4_CRIGR Computationally mapped isoform of Lateral signaling target protein 2 homolog OS=Cricetulus griseus OX=10029 GN=Zfyve28 PE=3 SV=1 CANONICAL=A0A9J7HFE3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HFE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFE3/entry#A0A9J7HFE3-1", "sequence": { "sequence": "MEECIPQDRAPRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNRELESMAMRPLAKELTRSLEDVRGTLRDQALRDLNTYTEKMREALRHFDVLFAEFELSYVSAMVPVKSPREYYVQQEVIVLFCETVERALDFGYLTQDMIDDYEPALMFTIPRLAIVCGLVVYADGPLNLDRKVEDMSELFRPFHTLLRKIRDLLQALTEEELHTLERSLCVSQDVELPIRADTQAPSALAPTFSTSLPPEEPLSASASNSEAELACSMQYDDQELEELSRMVHRAGDEMSSLLSPPSACQSPAHRPGTEASPRGEASPARARLKSGSDEEERVFFMDDVEVAESPARSESPGDTFELTGSMQSNVQQRGQDSQSGEVGVGAPSLVKEEDWSNNNIEDDKIKLASLVGSTSCSCLDSQLYLDGWEVNTDDAETAEMIAHRTGGMKLSATVIFNPKSHASLDSAVATQEATDRGISPLEPRAEGTGDNSHKLGTAATNCLLHSCVCCGSCGDSREDAVEHLQEKCGPGSIISASNPSVSLAKAGDKEPERLDEAWSSPDVTLPAEDASSGQEPKAPAPNKCLAHTSGPQVDTASRLQGEGEVKRQPELETRNQDPEKSSVVRGDSPREDMAQTEPQHLSGSSSSTAGSCSLDNTRLEVAPAAMPLTPMATREKIRSRFHGSHDLIHRLFVCISGVADQLQTNYASDLRSILKTLFEVMATKPETDDKEKLKKVTQTLRSAALEDCALCQETVSSSELAAKTRDGDFEDPPEWVPDEACGFCTSCKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCYMFHVTPFYSDKTGM", "length": 840, "header": "tr|A0A9J7HFE3-1|A0A9J7HFE3_CRIGR Isoform 1 of Lateral signaling target protein 2 homolog OS=Cricetulus griseus OX=10029 GN=Zfyve28 PE=3 SV=1 CANONICAL=A0A9J7HFE3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771033", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771033", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFE3" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFE3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFE3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HFE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFE3" }, { "id": "PS50178", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50178" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FYVE-type", "eco_id": "ECO_0000259", "start_pos": 770, "end_pos": 826, "start_aa": "Asp", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HCC8-1", "uniprot_ac": "A0A9J7HCC8", "uniprot_id": "A0A9J7HCC8_CRIGR", "mass": { "chemical_mass": 71527.0, "monoisotopic_mass": 71527.0 }, "refseq": { "ac": "XP_035308958", "name": "LIM domain-binding protein 3 isoform X12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308958" }, "gene_names": [ { "name": "Ldb3", "type": "recommended", "evidence": [ { "id": "A0A9J7HCC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCC8" } ] }, { "name": "Ldb3", "type": 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##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. 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"MGYAQGPVVIPKDHFQQRPAMEPGFQAGCSVHSEKGCKLQGPPGQQCLDLPEYSPTGGGFSFDPVLPTVELDCGVLRTCAVLRPDSAGALGCIHLYYVGGEVYVECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSVKIFNNQEFAQILAQSVNHGFETVYELTKMCTIRMSFVKGWGAKYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS", "length": 224, "header": "tr|A0A9J7HCD9-1|A0A9J7HCD9_CRIGR Isoform 1 of Mothers against decapentaplegic homolog 1-like OS=Cricetulus griseus OX=10029 GN=LOC113839005 PE=4 SV=1 CANONICAL=A0A9J7HCD9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HCD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCD9/entry#A0A9J7HCD9-1", "sequence": { "sequence": "MGYAQGPVVIPKDHFQQRPAMEPGFQAGCSVHSEKGCKLQGPPGQQCLDLPEYSPTGGGFSFDPVLPTVELDCGVLRTCAVLRPDSAGALGCIHLYYVGGEVYVECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSVKIFNNQEFAQILAQSVNHGFETVYELTKMCTIRMSFVKGWGAKYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS", "length": 224, "header": "tr|A0A9J7HCD9-1|A0A9J7HCD9_CRIGR Isoform 1 of Mothers against decapentaplegic homolog 1-like OS=Cricetulus griseus OX=10029 GN=LOC113839005 PE=4 SV=1 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"name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCD9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCD9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCD9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCD9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCD9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCD9" } ], "pmid": "" }, { "name": "I-SMAD binding", "id": "GO:0070411", "url": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A9J7HCE0-1", "uniprot_ac": "A0A9J7HCE0", "uniprot_id": "A0A9J7HCE0_CRIGR", "mass": { "chemical_mass": 21503.0, "monoisotopic_mass": 21503.0 }, "refseq": { "ac": "XP_035309661", "name": "GTPase KRas-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309661" }, "gene_names": [ { "name": "LOC118239801", "type": "recommended", "evidence": [ { "id": "A0A9J7HCE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE0" } ] }, { "name": "LOC118239801", "type": "synonym", "evidence": [ { "id": "XP_035309661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309661" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A9J7HCE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE0/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A9J7HCE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE0/entry#names_and_taxonomy" } ] }, { "name": "GTPase KRas-like", "type": "synonym", "evidence": [ { "id": "XP_035309661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309661" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276937.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309661" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCE0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC118239801", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE0", "locus": {} } ], "crossref": [ { "id": "A0A9J7HCE0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HCE0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04138", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04138", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "118239801", "url": "https://www.ncbi.nlm.nih.gov/gene/118239801", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:118239801", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239801", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HCE0", "url": "https://www.orthodb.org/?gene=A0A9J7HCE0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309661", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HCE0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEYKLVVVGADGVGKTALTIQLIQYHFVDVYDPTIEDSYKKQVVIDGENCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAMNNTKSFEDIHHFREQIKRAKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRKHKEKMSKDGKKKKKKSKTKCIIM", "length": 188, "header": "tr|A0A9J7HCE0-1|A0A9J7HCE0_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC118239801 PE=3 SV=1 CANONICAL=A0A9J7HCE0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HCE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE0/entry#A0A9J7HCE0-1", "sequence": { "sequence": "MTEYKLVVVGADGVGKTALTIQLIQYHFVDVYDPTIEDSYKKQVVIDGENCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAMNNTKSFEDIHHFREQIKRAKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRKHKEKMSKDGKKKKKKSKTKCIIM", "length": 188, "header": "tr|A0A9J7HCE0-1|A0A9J7HCE0_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC118239801 PE=3 SV=1 CANONICAL=A0A9J7HCE0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], 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Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 57% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276853.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309610", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309610" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCE5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113838275", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCE5", "locus": {} } ], "crossref": [ { "id": "A0A9J7HCE5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HCE5", "database": "AlphaFoldDB", "categories": [] }, { "id": "113838275", "url": "https://www.ncbi.nlm.nih.gov/gene/113838275", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309407" } ] }, { "annotation": "Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. Binds to polypyrimidine-rich controlling element (PCE) of CFTR and promotes exon skipping of CFTR exon 9, thereby antagonizing TIA1 and its role in exon inclusion of CFTR exon 9. Plays a role in the splicing of pyruvate kinase PKM by binding repressively to a polypyrimidine tract flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HGM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGM2#function" }, { "database": "UniProtKB", "id": "ARBA00055436", "url": "https://www.uniprot.org/uniprotkb/ARBA00055436#function" }, { "database": "UniProtKB", "id": "A0A9J7HCF6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCF6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HGM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGM2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": 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"https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113839052", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113839052", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HGM2", "url": "https://www.orthodb.org/?gene=A0A9J7HGM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309407", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HCF6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HGM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HGM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGIVPDIAVGTKRGSDELFSTCVSNGPFIMSSSTSAANGNDSKKFKGDNRNTGVPSRVIHVRSLPSDVTEGKVISLGLPFGKVTNLLMLKGKNQAFIVMNTEEAANTMVNYYTSVTPVLHGQPIYIQFSNHKELKTDSSPNHARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGESPVLRILVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNRFQALLQYADPVSAQHAKLSLDGQNIYKAWCTLRIDFSKLTSLYVKYNNDKSRDYTRPDLPSGDSQPSLDQTVAAAFGLSVPNVHGALAPLAIPCAASAAAAGRIAIPGLAGAGISVLLVSNLNPERVTPQSLFILFGVYGDVLRVKILFNNKENALVQMADGSQAQRAMSHLNGHKLHGNSLRIILSKHQSVQLPREGQEDQGVTKDYGSSPLHRFKKPGSKNFQNIFPPSPTLHLSNIPPSVSEDDLKNLFSSNGGVIKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGDNHHLRVSFSKSTI", "length": 529, "header": "tr|A0A9J7HGM2-1|A0A9J7HGM2_CRIGR Isoform 1 of Polypyrimidine tract-binding protein 1 OS=Cricetulus griseus OX=10029 GN=LOC113839052 PE=4 SV=1 CANONICAL=A0A9J7HGM2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HCF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGM2/entry#A0A9J7HCF6-1", "sequence": { "sequence": "MDGIVPDIAVGTKRGSDELFSTCVSNGPFIMSSSTSAVISLGLPFGKVTNLLMLKGKNQAFIVMNTEEAANTMVNYYTSVTPVLHGQPIYIQFSNHKELKTDSSPNHARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGESPVLRILVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNRFQALLQYADPVSAQHAKLSLDGQNIYKAWCTLRIDFSKLTSLYVKYNNDKSRDYTRPDLPSGDSQPSLDQTVAAAFGLSVPNVHGALAPLAIPCAASAAAAGRIAIPGLAGAGISVLLVSNLNPERVTPQSLFILFGVYGDVLRVKILFNNKENALVQMADGSQAQRAMSHLNGHKLHGNSLRIILSKHQSVQLPREGQEDQGVTKDYGSSPLHRFKKPGSKNFQNIFPPSPTLHLSNIPPSVSEDDLKNLFSSNGGVIKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGDNHHLRVSFSKSTI", "length": 493, "header": "tr|A0A9J7HCF6-1|A0A9J7HCF6_CRIGR Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein I OS=Cricetulus griseus OX=10029 GN=LOC113839052 PE=4 SV=1 CANONICAL=A0A9J7HGM2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HGM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGM2/entry#A0A9J7HGM2-1", "sequence": { "sequence": "MDGIVPDIAVGTKRGSDELFSTCVSNGPFIMSSSTSAANGNDSKKFKGDNRNTGVPSRVIHVRSLPSDVTEGKVISLGLPFGKVTNLLMLKGKNQAFIVMNTEEAANTMVNYYTSVTPVLHGQPIYIQFSNHKELKTDSSPNHARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGESPVLRILVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNRFQALLQYADPVSAQHAKLSLDGQNIYKAWCTLRIDFSKLTSLYVKYNNDKSRDYTRPDLPSGDSQPSLDQTVAAAFGLSVPNVHGALAPLAIPCAASAAAAGRIAIPGLAGAGISVLLVSNLNPERVTPQSLFILFGVYGDVLRVKILFNNKENALVQMADGSQAQRAMSHLNGHKLHGNSLRIILSKHQSVQLPREGQEDQGVTKDYGSSPLHRFKKPGSKNFQNIFPPSPTLHLSNIPPSVSEDDLKNLFSSNGGVIKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGDNHHLRVSFSKSTI", "length": 529, "header": "tr|A0A9J7HGM2-1|A0A9J7HGM2_CRIGR Isoform 1 of Polypyrimidine tract-binding protein 1 OS=Cricetulus griseus OX=10029 GN=LOC113839052 PE=4 SV=1 CANONICAL=A0A9J7HGM2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:113839052", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113839052", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HGM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGM2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HGM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HGM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGM2" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HGM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGM2" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HGM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGM2" } ], "pmid": "" }, { "name": "negative regulation of mRNA metabolic process", "id": "GO:1903312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903312", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HGM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HGM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGM2" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 142, "start_aa": "Arg", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A9J7HCG6-1", "uniprot_ac": "A0A9J7HCG6", "uniprot_id": "A0A9J7HCG6_CRIGR", "mass": { "chemical_mass": 17414.0, "monoisotopic_mass": 17414.0 }, "refseq": { "ac": "XP_035309421", "name": "ephrin-B2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309421" }, "gene_names": [ { "name": "LOC118239749", "type": "recommended", "evidence": [ { "id": "A0A9J7HCG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG6" } ] }, { "name": "LOC118239749", "type": "synonym", "evidence": [ { "id": "XP_035309421", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309421" } ] } ], "protein_names": [ { "name": "Ephrin-B2-like", "type": "synonym", "evidence": [ { "id": "A0A9J7HCG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG6/entry#names_and_taxonomy" } ] }, { "name": "ephrin-B2-like", "type": "synonym", "evidence": [ { "id": "XP_035309421", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309421" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309421", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309421" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC118239749", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG6", "locus": {} } ], "crossref": [ { "id": "A0A9J7HCG6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HCG6", "database": "AlphaFoldDB", "categories": [] }, { "id": "118239749", "url": "https://www.ncbi.nlm.nih.gov/gene/118239749", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:118239749", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239749", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR11304", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11304", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11304:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11304:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00812", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00812", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309421", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309421", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HCG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSMSRLRRDSAWKYCWGFLMVFCRTAISSPTVLEPIYWNSSNSRFLPGQGLVLYPQIGDKLDIICPKVDSKTVGQYEYYKLYMVDKDQADRCTIKKKNTPLLNCSIPQQDVKFTIKFQEFSPNICGLEFQENKDYYIIWANLPGFLWY", "length": 148, "header": "tr|A0A9J7HCG6-1|A0A9J7HCG6_CRIGR Isoform 1 of Ephrin-B2-like OS=Cricetulus griseus OX=10029 GN=LOC118239749 PE=3 SV=1 CANONICAL=A0A9J7HCG6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HCG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCG6/entry#A0A9J7HCG6-1", "sequence": { "sequence": "MSMSRLRRDSAWKYCWGFLMVFCRTAISSPTVLEPIYWNSSNSRFLPGQGLVLYPQIGDKLDIICPKVDSKTVGQYEYYKLYMVDKDQADRCTIKKKNTPLLNCSIPQQDVKFTIKFQEFSPNICGLEFQENKDYYIIWANLPGFLWY", "length": 148, "header": "tr|A0A9J7HCG6-1|A0A9J7HCG6_CRIGR Isoform 1 of Ephrin-B2-like OS=Cricetulus griseus OX=10029 GN=LOC118239749 PE=3 SV=1 CANONICAL=A0A9J7HCG6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:118239749", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239749", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCG6", "url": 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This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. 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"OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309469", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309469", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HCJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HGR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HGR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEYKLVVVGADGVGKTALTIQLIQYHFVDVYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAMNNTKSFEAIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLAGSYGIPFIETSAKTRQRVEDAFYALVREIRQYRLKKISKEEKTPGKVKIKKCIVM", "length": 189, "header": "tr|A0A9J7HGR2-1|A0A9J7HGR2_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113837935 PE=3 SV=1 CANONICAL=A0A9J7HGR2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HCJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGR2/entry#A0A9J7HCJ5-1", "sequence": { "sequence": "MSEYKLVVVGADGVGKTALTIQLIQYHFVDVYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAMNNTKSFEAIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLAGSYGIPFIETSAKTRQRVEDAFYALVREIRQYRLKKINGKKKKKKTKSKCIIM", "length": 187, "header": "tr|A0A9J7HCJ5-1|A0A9J7HGR2_CRIGR Computationally mapped isoform of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113837935 PE=3 SV=1 CANONICAL=A0A9J7HGR2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HGR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGR2/entry#A0A9J7HGR2-1", "sequence": { "sequence": "MSEYKLVVVGADGVGKTALTIQLIQYHFVDVYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAMNNTKSFEAIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLAGSYGIPFIETSAKTRQRVEDAFYALVREIRQYRLKKISKEEKTPGKVKIKKCIVM", "length": 189, "header": "tr|A0A9J7HGR2-1|A0A9J7HGR2_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113837935 PE=3 SV=1 CANONICAL=A0A9J7HGR2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JZY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGR2/entry#A0A9J7JZY2-1", "sequence": { "sequence": "MSEYKLVVVGADGVGKTALTIQLIQYHFVDVYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAMNNTKSFEAIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLAGSYGIPFIETSAKTRQGVGDAFYTLV", "length": 160, "header": "tr|A0A9J7JZY2-1|A0A9J7HGR2_CRIGR Computationally mapped isoform of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113837935 PE=3 SV=1 CANONICAL=A0A9J7HGR2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "cge:113837935", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837935", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HGR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGR2" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HGR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGR2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HGR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGR2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HGR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HGR2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRJ8-1", "G3GY22-1", "G3H2D6-1", "G3HID1-1", "A0A9J7FY79-1", "G3IBI0-1", "G3HIM4-1", "G3HLW5-1", "G3I0B0-1", "G3H8L7-1", "G3IMU0-1", "G3HQ45-1", "G3HX83-1", "G3H515-1", "G3HRK4-1", "G3HWS3-1", "G3I185-1", "G3I2E9-1", "G3IHJ9-1", "G3I5Q9-1", "G3H3P1-1", "G3HGA7-1", "A0A9J7K0Q7-1", "G3I8B8-1", "A0A9J7FPY4-1", "A0A9J7JNI7-1", "A0A9J7JTM0-1", "G3HXK0-1", "G3I1T6-1", "A0A8C2M8V3-1", "G3HAT4-1", "G3HBU1-1", "A0A8C2MG78-1", "A0A9J7JFJ5-1", "A0A061I5F7-1", "A0A9J7GMX4-1", "G3H3X0-1", "A0A8C2MG41-1", "A0A8C2MJU2-1", "A0A8C2MKJ3-1", "A0A8C2QMP3-1", "A0A9J7F720-1", "A0A061IFE4-1", "A0A061HZZ7-1", "A0A8C2M6H7-1", "A0A8C2M9W6-1", "A0A9J7H2L4-1", "A0A8C2MH13-1", "A0A8C2MMV7-1", "A0A8C2MPE2-1", "A0A8C2LL65-1", "A0A3L7HXE9-1", "A0A8C2LGZ8-1", "A0A8C2LIB5-1", "A0A8C2LNU7-1", "A0A9J7JYH7-1", "A0A8C2LV21-1", "A0A9J7GDV9-1", "A0A8C2QEY0-1", "A0A9J7FVQ6-1", "A0A9J7K0X9-1", "A0A9J7J7P8-1", "A0A8C2M2X0-1", "A0A8C2MAV7-1", "A0A8C2MQL3-1", "A0A3L7HA69-1", "A0A8C2LLE7-1", "A0A061HWM0-1", "A0A061I5K5-1", "A0A061IH58-1", "A0A061INW8-1", "A0A3L7GXQ2-1", "A0A9J7GN19-1", "A0A3L7HQ44-1", "A0A3L7IA35-1", "A0A3L7IMK5-1", "A0A8C2LIE2-1", "A0A9J7GAZ9-1", "A0A9J7HCG9-1", "A0A9J7HC46-1", "A0A9J7HC79-1", "A0A9J7HCE0-1", "A0A9J7JRE1-1", "A0A9J7GJ78-1", "A0A9J7GKH5-1", "A0A9J7GL76-1", "A0A9J7GLC6-1", "A0A9J7GRC9-1", "A0A9J7GM12-1", "A0A9J7GM74-1", "A0A9J7GP64-1", "A0A9J7GPV5-1", "A0A9J7GQI1-1", "A0A9J7GR82-1", "A0A9J7JY44-1", "A0A9J7JTP9-1", "A0A9J7HGR2-1", "A0A9J7JZZ6-1", "A0A9J7K3I9-1", "A0A9J7K4X6-1", "A0A9J7HD72-1", "A0A9J7KEX2-1", "A0A9J7KFX8-1", "A0A9J7KEY0-1", "A0A9J7KF02-1", "A0A9J7KF14-1", "A0A9J7HFH8-1", "A0A9J7HEY0-1", "A0A9J7KG38-1", "A0A9J7HCJ6-1", "A0A9J7HCM3-1", 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This record is derived from a genomic sequence (NW_023277137.1) annotated using gene prediction method: Gnomon. 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"OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309742", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309742", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HCJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEYKLVVVGADGVGKSALTIQLIQNLFVDEYDPTIEDSYRKQVVIDREICHLDILDTAGLEEYSAMRDQYMKTGEGFLCVFAMNNTKSFEAIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRQNRLKKISKEEKTPGRVKIKKCIVM", "length": 189, "header": "tr|A0A9J7HCJ6-1|A0A9J7HCJ6_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113837960 PE=3 SV=1 CANONICAL=A0A9J7HCJ6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HCJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ6/entry#A0A9J7HCJ6-1", "sequence": { "sequence": "MTEYKLVVVGADGVGKSALTIQLIQNLFVDEYDPTIEDSYRKQVVIDREICHLDILDTAGLEEYSAMRDQYMKTGEGFLCVFAMNNTKSFEAIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRQNRLKKISKEEKTPGRVKIKKCIVM", "length": 189, "header": "tr|A0A9J7HCJ6-1|A0A9J7HCJ6_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113837960 PE=3 SV=1 CANONICAL=A0A9J7HCJ6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "cge:113837960", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837960", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ6" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRJ8-1", "G3GY22-1", "G3H2D6-1", "G3HID1-1", "A0A9J7FY79-1", "G3IBI0-1", "G3HIM4-1", "G3HLW5-1", "G3I0B0-1", "G3H8L7-1", "G3IMU0-1", "G3HQ45-1", "G3HX83-1", "G3H515-1", "G3HRK4-1", "G3HWS3-1", "G3I185-1", "G3I2E9-1", "G3IHJ9-1", "G3I5Q9-1", "G3H3P1-1", "G3HGA7-1", "A0A9J7K0Q7-1", "G3I8B8-1", "A0A9J7FPY4-1", "A0A9J7JNI7-1", "A0A9J7JTM0-1", "G3HXK0-1", "G3I1T6-1", "A0A8C2M8V3-1", "G3HAT4-1", "G3HBU1-1", "A0A8C2MG78-1", "A0A9J7JFJ5-1", "A0A061I5F7-1", "A0A9J7GMX4-1", "G3H3X0-1", "A0A8C2MG41-1", "A0A8C2MJU2-1", "A0A8C2MKJ3-1", "A0A8C2QMP3-1", "A0A9J7F720-1", "A0A061IFE4-1", "A0A061HZZ7-1", "A0A8C2M6H7-1", "A0A8C2M9W6-1", "A0A9J7H2L4-1", "A0A8C2MH13-1", "A0A8C2MMV7-1", "A0A8C2MPE2-1", "A0A8C2LL65-1", "A0A3L7HXE9-1", "A0A8C2LGZ8-1", "A0A8C2LIB5-1", "A0A8C2LNU7-1", "A0A9J7JYH7-1", "A0A8C2LV21-1", "A0A9J7GDV9-1", "A0A8C2QEY0-1", "A0A9J7FVQ6-1", "A0A9J7K0X9-1", "A0A9J7J7P8-1", "A0A8C2M2X0-1", "A0A8C2MAV7-1", "A0A8C2MQL3-1", "A0A3L7HA69-1", "A0A8C2LLE7-1", "A0A061HWM0-1", "A0A061I5K5-1", "A0A061IH58-1", "A0A061INW8-1", "A0A3L7GXQ2-1", "A0A9J7GN19-1", "A0A3L7HQ44-1", "A0A3L7IA35-1", "A0A3L7IMK5-1", "A0A8C2LIE2-1", "A0A9J7GAZ9-1", "A0A9J7HCG9-1", "A0A9J7HC46-1", "A0A9J7HC79-1", "A0A9J7HCE0-1", "A0A9J7JRE1-1", "A0A9J7GJ78-1", 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"database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HWM0", "gene_name": "LOC113837706", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061HWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HWM0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061HWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HWM0" } ] } ] }, { "uniprot_ac": "A0A061HZZ7", "gene_name": "Rab9b", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061HZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZZ7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061HZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZZ7" } ] } ] }, { 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HEX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HFN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HFN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEYKLVVVGADGVGKSALTIQLIHNHFVDVYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFSMNNTKSFEAIPHYREQIKRAKDSEDVPMVLVGNKCDLPSRTVDTNQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIREYRLKKISKEEKTPGRVKNKKCNVM", "length": 189, "header": "tr|A0A9J7HFN4-1|A0A9J7HFN4_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC118239767 PE=3 SV=1 CANONICAL=A0A9J7HFN4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HCL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFN4/entry#A0A9J7HCL3-1", "sequence": { "sequence": "MSEYKLVVVGADGVGKSALTIQLIHNHFVDVYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFSMNNTKSFEAIPHYREQIKRAKDSEDVPMVLVGNKCDLPSRTVDTNQAQDLAGSYGIPFIETSAKTRQGVDDAFYTLV", "length": 160, "header": "tr|A0A9J7HCL3-1|A0A9J7HFN4_CRIGR Computationally mapped isoform of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC118239767 PE=3 SV=1 CANONICAL=A0A9J7HFN4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HEX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFN4/entry#A0A9J7HEX0-1", "sequence": { "sequence": "MSEYKLVVVGADGVGKSALTIQLIHNHFVDVYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFSMNNTKSFEAIPHYREQIKRAKDSEDVPMVLVGNKCDLPSRTVDTNQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIREYRLKKINGKKKKKKSKTKCIIM", "length": 187, "header": "tr|A0A9J7HEX0-1|A0A9J7HEX0_CRIGR Computationally mapped isoform of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC118239767 PE=3 SV=1 CANONICAL=A0A9J7HFN4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HFN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFN4/entry#A0A9J7HFN4-1", "sequence": { "sequence": "MSEYKLVVVGADGVGKSALTIQLIHNHFVDVYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFSMNNTKSFEAIPHYREQIKRAKDSEDVPMVLVGNKCDLPSRTVDTNQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIREYRLKKISKEEKTPGRVKNKKCNVM", "length": 189, "header": "tr|A0A9J7HFN4-1|A0A9J7HFN4_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC118239767 PE=3 SV=1 CANONICAL=A0A9J7HFN4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "cge:118239767", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239767", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFN4" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFN4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFN4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFN4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRJ8-1", "G3GY22-1", "G3H2D6-1", "G3HID1-1", "A0A9J7FY79-1", "G3IBI0-1", "G3HIM4-1", "G3HLW5-1", "G3I0B0-1", "G3H8L7-1", "G3IMU0-1", "G3HQ45-1", "G3HX83-1", "G3H515-1", "G3HRK4-1", "G3HWS3-1", "G3I185-1", "G3I2E9-1", "G3IHJ9-1", "G3I5Q9-1", "G3H3P1-1", "G3HGA7-1", "A0A9J7K0Q7-1", "G3I8B8-1", "A0A9J7FPY4-1", "A0A9J7JNI7-1", "A0A9J7JTM0-1", "G3HXK0-1", "G3I1T6-1", "A0A8C2M8V3-1", "G3HAT4-1", "G3HBU1-1", "A0A8C2MG78-1", "A0A9J7JFJ5-1", "A0A061I5F7-1", "A0A9J7GMX4-1", "G3H3X0-1", "A0A8C2MG41-1", "A0A8C2MJU2-1", "A0A8C2MKJ3-1", "A0A8C2QMP3-1", "A0A9J7F720-1", "A0A061IFE4-1", "A0A061HZZ7-1", "A0A8C2M6H7-1", "A0A8C2M9W6-1", "A0A9J7H2L4-1", "A0A8C2MH13-1", "A0A8C2MMV7-1", 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} ], "crossref": [ { "id": "A0A9J7HCL7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HCL7", "database": "AlphaFoldDB", "categories": [] }, { "id": "118239780", "url": "https://www.ncbi.nlm.nih.gov/gene/118239780", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:118239780", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239780", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HCL7", "url": "https://www.orthodb.org/?gene=A0A9J7HCL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24062", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24062", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309573", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HCL7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISTDLAMGIIFLSQTALGILGNSALLCCLIISEFSVKRARPTDLIVKHLTSANFMVLLCKGIPQTLAALGWKYFLNTIACKIVFYFHRVARGVSLGSTALLGFFQAIIINPRNAKYKYFKATDHKVIGTSLSLCWSLQMMVNGFIPVLMTDLRDAKNVTGFRDLLYCAVPKPSYAFYVILLSSSDVMCLVLMIWACGSMVLVLLKHKQRLQYMHRVLCPKSSPETRATQTILVLVSSFVFFYTASGILVMCLTLVNGATRHLVNTSAATAACFPALCPYLLIRHYTPVSRLCCTC", "length": 296, "header": "tr|A0A9J7HCL7-1|A0A9J7HCL7_CRIGR Isoform 1 of Vomeronasal type-1 receptor OS=Cricetulus griseus OX=10029 GN=LOC118239780 PE=3 SV=1 CANONICAL=A0A9J7HCL7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HCL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCL7/entry#A0A9J7HCL7-1", "sequence": { "sequence": "MISTDLAMGIIFLSQTALGILGNSALLCCLIISEFSVKRARPTDLIVKHLTSANFMVLLCKGIPQTLAALGWKYFLNTIACKIVFYFHRVARGVSLGSTALLGFFQAIIINPRNAKYKYFKATDHKVIGTSLSLCWSLQMMVNGFIPVLMTDLRDAKNVTGFRDLLYCAVPKPSYAFYVILLSSSDVMCLVLMIWACGSMVLVLLKHKQRLQYMHRVLCPKSSPETRATQTILVLVSSFVFFYTASGILVMCLTLVNGATRHLVNTSAATAACFPALCPYLLIRHYTPVSRLCCTC", "length": 296, "header": "tr|A0A9J7HCL7-1|A0A9J7HCL7_CRIGR Isoform 1 of Vomeronasal type-1 receptor OS=Cricetulus griseus OX=10029 GN=LOC118239780 PE=3 SV=1 CANONICAL=A0A9J7HCL7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:118239780", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239780", "resource": "KEGG 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"name": "pheromone receptor activity", "id": "GO:0016503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016503", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCL7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCL7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HCL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCL7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 282, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 265, "end_pos": 267 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A9J7J7I6-1", "uniprot_ac": "A0A9J7J7I6", "uniprot_id": "A0A9J7J7I6_CRIGR", "mass": { "chemical_mass": 50373.0, "monoisotopic_mass": 50373.0 }, "refseq": { "ac": "XP_027248576", "name": "transcription factor AP-2-beta isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248576" }, "gene_names": [ { "name": "Tfap2b", "type": "recommended", "evidence": [ { "id": "A0A9J7J7I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7I6" } ] }, { "name": "Tfap2b", "type": "synonym", "evidence": [ { "id": "XP_027248576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248576" } ] } ], "protein_names": [ { "name": "Transcription factor AP-2-beta isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7J7I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7I6/entry#names_and_taxonomy" } ] }, { "name": "transcription factor AP-2-beta isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027248576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248576" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027248576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248576" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J7I6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7I6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tfap2b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7I6", "locus": {} } ], "crossref": [ { "id": "A0A9J7J7I6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J7I6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100754417", "url": "https://www.ncbi.nlm.nih.gov/gene/100754417", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754417", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754417", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7J7I6", "url": "https://www.orthodb.org/?gene=A0A9J7J7I6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10812", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10812", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10812:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10812:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03299", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03299", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027248576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248576", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HCL8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HG59", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HG59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HG59-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HG59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7I6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7I6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J7I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7I6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHSPPRDQAAIMLWKLVENVKYEDIYEDRHDGVPSHSSRLSQLGSVSQGPYSSAPPLSHTPSSDFQPPYFPPPYQPLPYHQSQDPYSHVNDPYSLNPLHQPQQHPWGQRQRQEVGSEAGSLLPQPRAALPQLSGLDPRRDYHSVRRPDVLLHSAHHGLDAGMGDSLSLHGLGHPGMEDVQSVEDANNSGMNLLDQSVIKKVPVPPKSVTSLMMNKDGFLGGMSVNTGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYICETEFPAKAVSEYLNRQHTDPSDLHSRKNMLLATKQLCKEFTDLLAQDRTPIGNSRPSPILEPGIQSCLTHFSLITHGFGAPAICAALTALQNYLTEALKGMDKMFLNNTTNRHTSGEGPGSKTGDKEEKHRK", "length": 459, "header": "tr|A0A9J7J7I6-1|A0A9J7J7I6_CRIGR Isoform 1 of Transcription factor AP-2-beta isoform X1 OS=Cricetulus griseus OX=10029 GN=Tfap2b PE=3 SV=1 CANONICAL=A0A9J7J7I6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HCL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7I6/entry#A0A9J7HCL8-1", "sequence": { "sequence": "MLVHTYSSMDRHDGVPSHSSRLSQLGSVSQGPYSSAPPLSHTPSSDFQPPYFPPPYQPLPYHQSQDPYSHVNDPYSLNPLHQPQQHPWGQRQRQEVGSEAGSLLPQPRAALPQLSGLDPRRDYHSVRRPDVLLHSAHHGLDAGMGDSLSLHGLGHPGMEDVQSVEDANNSGMNLLDQSVIKKVPVPPKSVTSLMMNKDGFLGGMSVNTGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYICETEFPAKAVSEYLNRQHTDPSDLHSRKNMLLATKQLCKEFTDLLAQDRTPIGNSRPSPILEPGIQSCLTHFSLITHGFGAPAICAALTALQNYLTEALKGMDKMFLNNTTNRHTSGEGPGSKTGDKEEKHRK", "length": 441, "header": "tr|A0A9J7HCL8-1|A0A9J7HCL8_CRIGR Computationally mapped isoform of Transcription factor AP-2-beta isoform X3 OS=Cricetulus griseus OX=10029 GN=Tfap2b PE=3 SV=1 CANONICAL=A0A9J7J7I6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HG59-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7I6/entry#A0A9J7HG59-1", "sequence": { "sequence": "MHSPPRDQAAIMLWKLVENVKYEDIYEDRHDGVPSHSSRLSQLGSVSQGPYSSAPPLSHTPSSDFQPPYFPPPYQPLPYHQSQDPYSHVNDPYSLNPLHQPQQHPWGQRQRQEVGSEAGSLLPQPRAALPQLSGLDPRRDYHSVRRPDVLLHSAHHGLDAGMGDSLSLHGLGHPGMEDVQSVEDANNSGMNLLDQSVIKKVPVPPKSVTSLMMNKDGFLGGMSVNTGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYICETEFPAKAVSEYLNRQHTDPSDLHSRKNMLLATKQLCKEFTDLLAQDRTPIGNSRPSPILEPGIQSCLTHFSLITHGFGAPAICAALTALQNYLTEALKGMDKMFLNNTTNRHTSGEGPGQRAPRV", "length": 453, "header": "tr|A0A9J7HG59-1|A0A9J7HG59_CRIGR Computationally mapped isoform of Transcription factor AP-2-beta isoform X2 OS=Cricetulus griseus OX=10029 GN=Tfap2b PE=3 SV=1 CANONICAL=A0A9J7J7I6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J7I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J7I6/entry#A0A9J7J7I6-1", "sequence": { "sequence": 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Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 100% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A9J7HCM9-1", "uniprot_ac": "A0A9J7HCM9", "uniprot_id": "A0A9J7HCM9_CRIGR", "mass": { "chemical_mass": 96236.0, "monoisotopic_mass": 96236.0 }, "refseq": { "ac": "XP_035309611", "name": "zinc finger protein 879-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309611" }, "gene_names": [ { "name": "LOC113839138", "type": "recommended", "evidence": [ { "id": "A0A9J7HCM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCM9" } ] }, { "name": "LOC113839138", "type": "synonym", "evidence": [ { "id": "XP_035309611", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309611" } ] } ], "protein_names": [ { "name": "Zinc finger protein 879-like", "type": "synonym", "evidence": [ { "id": "A0A9J7HCM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCM9/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 879-like", "type": "synonym", "evidence": [ { "id": "XP_035309611", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309611" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 71% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276853.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309611", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309611" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCM9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCM9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113839138", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCM9", "locus": {} } ], "crossref": [ { "id": "A0A9J7HCM9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HCM9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113839138", "url": "https://www.ncbi.nlm.nih.gov/gene/113839138", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113839138", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113839138", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HCM9", "url": "https://www.orthodb.org/?gene=A0A9J7HCM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309611", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309611", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HCM9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLKRESLETRSPENDCGLEKTEFIPTRASPVQFREDNSNSPVSEVNIPPIGNGSCAKQELQYLWEMFTSWLQPEKQTKEQMISQLVMEQFFKTGHYKDKLAMKEKWESSGRNMVKLMENLTDECVEPPKMFHVSMQGEEGLFPGHMSLNEVINLLKEMKSSTTSTSTQENKGTTLQSPLNKLLPTGREDSGDGYNNPLNLSKVNTSDRSPGNEMNSLVTIEKYNCPETEERGDSDGISQDFRCSRHHQVSICGSSSVSVPKDKDQPEVVVPVEQPQPGIITRAEKTADSQNCETDHTGESVQERSSRVPKTHQCVECLRTFRYPSQLLAHKRRHKKSLLTFKDVAINFSKEEWECLHTSQKDLYRDVMLENYGNLVSILGETQREAPNPNGDTKIQNIGKQIRSQIAIHKIFHVSMQGEEGLFPGHMSLNEVINLLKEMKSSTTSTSTQENKRTTLQSPLNKLLPTGHEDSGDGYNNPLNLSKVNTSDRSPGNEMDSLVIIEKYNCPETEERGDSDGVSQDFRCSRHHQVSLSGSSSVSVPKDKDQPEVVDPVEQPQPGIITRAEKTGDSQNCETDHTGSNLQVHQRIHTGEKPYNCKACGKSFTNGSDLQVHQRIHTGEKPYNCTDCGKSFTTGSNLQVHQRIHAGKKPYHCKVCGKSFTSGSDLQVHQRIHTGEKPYNCTDCGKSFTTGSNLQVHQRIHTGKKPYNCTDCRKSFTTGSNLQVHQRIHTGKKPYHCKVCGKSFTSGSGFQVHQRIHTGEKPYNCKACGKSFIKGSHLQVHQRIHTGEKPYKCSDCGKFFKQQSHLQWHERIHTGEKPYKCSDCLSYNVKILILPGVQQLELAVVKILSVVVLED", "length": 857, "header": "tr|A0A9J7HCM9-1|A0A9J7HCM9_CRIGR Isoform 1 of Zinc finger protein 879-like OS=Cricetulus griseus OX=10029 GN=LOC113839138 PE=3 SV=1 CANONICAL=A0A9J7HCM9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HCM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCM9/entry#A0A9J7HCM9-1", "sequence": { "sequence": "MASLKRESLETRSPENDCGLEKTEFIPTRASPVQFREDNSNSPVSEVNIPPIGNGSCAKQELQYLWEMFTSWLQPEKQTKEQMISQLVMEQFFKTGHYKDKLAMKEKWESSGRNMVKLMENLTDECVEPPKMFHVSMQGEEGLFPGHMSLNEVINLLKEMKSSTTSTSTQENKGTTLQSPLNKLLPTGREDSGDGYNNPLNLSKVNTSDRSPGNEMNSLVTIEKYNCPETEERGDSDGISQDFRCSRHHQVSICGSSSVSVPKDKDQPEVVVPVEQPQPGIITRAEKTADSQNCETDHTGESVQERSSRVPKTHQCVECLRTFRYPSQLLAHKRRHKKSLLTFKDVAINFSKEEWECLHTSQKDLYRDVMLENYGNLVSILGETQREAPNPNGDTKIQNIGKQIRSQIAIHKIFHVSMQGEEGLFPGHMSLNEVINLLKEMKSSTTSTSTQENKRTTLQSPLNKLLPTGHEDSGDGYNNPLNLSKVNTSDRSPGNEMDSLVIIEKYNCPETEERGDSDGVSQDFRCSRHHQVSLSGSSSVSVPKDKDQPEVVDPVEQPQPGIITRAEKTGDSQNCETDHTGSNLQVHQRIHTGEKPYNCKACGKSFTNGSDLQVHQRIHTGEKPYNCTDCGKSFTTGSNLQVHQRIHAGKKPYHCKVCGKSFTSGSDLQVHQRIHTGEKPYNCTDCGKSFTTGSNLQVHQRIHTGKKPYNCTDCRKSFTTGSNLQVHQRIHTGKKPYHCKVCGKSFTSGSGFQVHQRIHTGEKPYNCKACGKSFIKGSHLQVHQRIHTGEKPYKCSDCGKFFKQQSHLQWHERIHTGEKPYKCSDCLSYNVKILILPGVQQLELAVVKILSVVVLED", "length": 857, "header": "tr|A0A9J7HCM9-1|A0A9J7HCM9_CRIGR Isoform 1 of Zinc finger protein 879-like OS=Cricetulus griseus OX=10029 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{ "name": "LOC113830747", "type": "synonym", "evidence": [ { "id": "XP_035307093", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307093" } ] } ], "protein_names": [ { "name": "Refilin-B-like", "type": "synonym", "evidence": [ { "id": "A0A9J7HCR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCR2/entry#names_and_taxonomy" } ] }, { "name": "refilin-B-like", "type": "synonym", "evidence": [ { "id": "XP_035307093", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307093" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307093", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307093" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCR2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113830747", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCR2", "locus": {} } ], "crossref": [ { "id": "A0A9J7HCR2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HCR2", "database": "AlphaFoldDB", "categories": [] }, { "id": "113830747", "url": "https://www.ncbi.nlm.nih.gov/gene/113830747", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028215", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028215", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113830747", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113830747", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HCR2", "url": "https://www.orthodb.org/?gene=A0A9J7HCR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31848", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31848", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31848:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31848:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15068", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15068", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307093", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307093", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HCR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HCR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCR2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGRLSLQDVPELVDTKKKGDGVLDSPDSGLPPSPSPSHWGLAAAAGGGGERVPVPGALEPDAAATPAIPNPASLTQSLAAVCSPRLCPLSFGEGVEFDPLPPKEIKYTSSVKYDSERHFIDDVQMPLGLAVASCSQTVTCIPNCTWRNYKAEVHFQPRHKAARFLSTTIIYPKYPKTIYTTTLDYNCHKKLRRFLSSVELEATEFLGSDGLSDEC", "length": 216, "header": "tr|A0A9J7HCR2-1|A0A9J7HCR2_CRIGR Isoform 1 of Refilin-B-like OS=Cricetulus griseus OX=10029 GN=LOC113830747 PE=3 SV=1 CANONICAL=A0A9J7HCR2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HCR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCR2/entry#A0A9J7HCR2-1", "sequence": { "sequence": "MVGRLSLQDVPELVDTKKKGDGVLDSPDSGLPPSPSPSHWGLAAAAGGGGERVPVPGALEPDAAATPAIPNPASLTQSLAAVCSPRLCPLSFGEGVEFDPLPPKEIKYTSSVKYDSERHFIDDVQMPLGLAVASCSQTVTCIPNCTWRNYKAEVHFQPRHKAARFLSTTIIYPKYPKTIYTTTLDYNCHKKLRRFLSSVELEATEFLGSDGLSDEC", "length": 216, "header": "tr|A0A9J7HCR2-1|A0A9J7HCR2_CRIGR Isoform 1 of Refilin-B-like OS=Cricetulus griseus OX=10029 GN=LOC113830747 PE=3 SV=1 CANONICAL=A0A9J7HCR2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 41% of CDS bases internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276919.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309650" } ] }, { "annotation": "Nucleolar protein that is involved in ribosomal RNA (rRNA) processing. Also plays a role in primary cilia resorption, and cell cycle progression in neurogenesis and neocortex development. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. 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"https://www.uniprot.org/uniprotkb/A0A9J7K451-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNLSSRKKSPTGNDMKSVQGAALRQQGFHDVNKRRAFLQDNSWIKKRPEEEKDENYGRVVLNRHNSHDALDRKITERDEPKATISRYRSDDTLDRTLSVLRTPEATKMPTGSSFLANNTTMAPTPASTPVKKKRQSWFPPPPPGHNASPNTGASRRDPVVHPPIPPKPSSPIASPKQPRQNNRQIHATRAGASGEANRHAEKNIRAEDLDDIIRVAASLQKTDKGEEMDNLIRMNKSLNRNQGLDGLFRANLKAQQADKRAQSLESLIYMNSQMDRDGKGNQAFGSLKKINQRTDKEKGSRDLDNLMKINSKGNENTSGKQDIDGSIKGNPETHKNMKRGQSLDNLIKVTPAVNRSNQGGQNLDNFIKAVFTTNRVNQGNQHGLDEFMNTSPKAVKTTAGHQDLDKFIKVNPDVLVNNQRNHDLDGIIRGNPTVTRNNQSQDLDNLIKVKPSALRNTNRDRSLENLTEVDSHVSENKNGRLDGQVNGFTNTQLKESTRTSVYSYDVRNSLSSDTGTRNAGPKDTVVYTRTYVESSKSPKDGYQENISGKYIQTVYSTSDRSVIERDMCTYCRKPLGAETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSKVMAKWIQQN", "length": 638, "header": "tr|A0A9J7HCY1-1|A0A9J7HCY1_CRIGR Isoform 1 of Sciellin OS=Cricetulus griseus OX=10029 GN=Scel PE=4 SV=1 CANONICAL=A0A9J7HCY1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HCY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCY1/entry#A0A9J7HCY1-1", "sequence": { "sequence": "MSNLSSRKKSPTGNDMKSVQGAALRQQGFHDVNKRRAFLQDNSWIKKRPEEEKDENYGRVVLNRHNSHDALDRKITERDEPKATISRYRSDDTLDRTLSVLRTPEATKMPTGSSFLANNTTMAPTPASTPVKKKRQSWFPPPPPGHNASPNTGASRRDPVVHPPIPPKPSSPIASPKQPRQNNRQIHATRAGASGEANRHAEKNIRAEDLDDIIRVAASLQKTDKGEEMDNLIRMNKSLNRNQGLDGLFRANLKAQQADKRAQSLESLIYMNSQMDRDGKGNQAFGSLKKINQRTDKEKGSRDLDNLMKINSKGNENTSGKQDIDGSIKGNPETHKNMKRGQSLDNLIKVTPAVNRSNQGGQNLDNFIKAVFTTNRVNQGNQHGLDEFMNTSPKAVKTTAGHQDLDKFIKVNPDVLVNNQRNHDLDGIIRGNPTVTRNNQSQDLDNLIKVKPSALRNTNRDRSLENLTEVDSHVSENKNGRLDGQVNGFTNTQLKESTRTSVYSYDVRNSLSSDTGTRNAGPKDTVVYTRTYVESSKSPKDGYQENISGKYIQTVYSTSDRSVIERDMCTYCRKPLGAETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSKVMAKWIQQN", "length": 638, "header": "tr|A0A9J7HCY1-1|A0A9J7HCY1_CRIGR Isoform 1 of Sciellin OS=Cricetulus griseus OX=10029 GN=Scel PE=4 SV=1 CANONICAL=A0A9J7HCY1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K451-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCY1/entry#A0A9J7K451-1", "sequence": { "sequence": "MSNLSSRKKSPTGNDMKSVQGAALRQQGFHDVNKRRAFLQDNSWIKKRPEEEKDENYGRVVLNRHNSHDALDRKITERDEPKATISRYRSDDTLDRTLSVLRTPEATKMPTGSSFLANNTTMAPTPASTPVKKKRQSWFPPPPPGHNASPNTGASRRDPVVHPPIPPKPSSPIASPKQPRQNNRQIHATRAGASGEANRHAEKNIRAEDLDDIIRVAASLQKTDKGEEMDNLIRMNKSLNRNQGLDGLFRANLKAQQADKRAQSLESLIYMNSQMDRDGKGNQAFGSLKKINQRTDKEKGRDLDNLMKINSKGNENTSGKQDIDGSIKGNPETHKNMKRGQSLDNLIKVTPAVNRSNQGGQNLDNFIKAVFTTNRVNQGNQHGLDEFMNTSPKAVKTTAGHQDLDKFIKVNPDVLVNNQRNHDLDGIIRGNPTVTRNNQSQDLDNLIKVKPSALRNTNRDRSLENLTEVDSHVSENKNGRLDGQVNGFTNTQLKESTRTSVYSYDVRNSLSSDTGTRNAGPKDTVVYTRTYVESSKSPKDGYQENISGKYIQTVYSTSDRSVIERDMCTYCRKPLGAETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSKVMAKWIQQN", "length": 637, "header": "tr|A0A9J7K451-1|A0A9J7HCY1_CRIGR Computationally mapped isoform of Sciellin OS=Cricetulus griseus OX=10029 GN=Scel PE=4 SV=1 CANONICAL=A0A9J7HCY1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 125, "start_aa": "Thr", "end_pos": 125, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr125", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K451", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K451" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K451", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K451" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763305", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763305", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCY1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCY1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCY1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "epidermis development", "id": "GO:0008544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008544", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCY2" } ] }, { "name": "LOC100763848", "type": "synonym", "evidence": [ { "id": "XP_035309798", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309798" } ] } ], "protein_names": [ { "name": "Actin-related protein 2", "type": "recommended", "evidence": [ { "id": "A0A9J7HCY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCY2/entry#names_and_taxonomy" } ] }, { "name": "Actin-like protein 2", "type": "synonym", "evidence": [ { "id": "A0A9J7HCY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCY2/entry#names_and_taxonomy" } ] }, { "name": "actin-related protein 2-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035309798", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309798" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277410.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309798", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309798" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCY2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100763848", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCY2", "locus": {} } ], "crossref": [ { "id": "A0A9J7HCY2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HCY2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10220", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10220", "database": "CDD", "categories": [ "Protein 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Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277053.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309717", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309717" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HCY8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCY8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC118239813", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCY8", "locus": {} } ], "crossref": [ { "id": "118239813", "url": "https://www.ncbi.nlm.nih.gov/gene/118239813", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein 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"total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A9J7HD26-1", "uniprot_ac": "A0A9J7HD26", "uniprot_id": "A0A9J7HD26_CRIGR", "mass": { "chemical_mass": 542316.0, "monoisotopic_mass": 542316.0 }, "refseq": { "ac": "XP_035307937", "name": "dynein heavy chain 8, axonemal isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307937" }, "gene_names": [ { "name": "Dnah8", "type": "recommended", "evidence": [ { "id": "A0A9J7HD26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD26" } ] }, { "name": "Dnah8", "type": "synonym", "evidence": [ { "id": "XP_035307937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307937" } ] } ], "protein_names": [ { "name": "Dynein heavy chain 8, axonemal isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7HD26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD26/entry#names_and_taxonomy" } ] }, { "name": "dynein heavy chain 8, axonemal isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035307937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307937" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307937", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307937" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD26" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dnah8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD26", "locus": {} } ], "crossref": [ { "id": "100763108", "url": "https://www.ncbi.nlm.nih.gov/gene/100763108", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013602", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013602", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035706", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035706", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763108", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763108", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HD26", "url": "https://www.orthodb.org/?gene=A0A9J7HD26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46532", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46532", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46532:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46532:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08393", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08393", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12774", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12774", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12775", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12775", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12781", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12781", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17852", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17852", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18198", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18199", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18199", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25007", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25007", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307937", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307937", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HD26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HD26-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD26-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 4730, "header": "tr|A0A9J7HD26-1|A0A9J7HD26_CRIGR Isoform 1 of Dynein heavy chain 8, axonemal isoform X2 OS=Cricetulus griseus OX=10029 GN=Dnah8 PE=3 SV=1 CANONICAL=A0A9J7HD26-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HD26-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD26/entry#A0A9J7HD26-1", "sequence": { "sequence": "MESEEGHTAPRSQSEEASTLEGIPPPRSDEDSAPRLYEDHAPTSEEQAPTSEDMTHPGEESQPTTLGEAPPTPDTPGTAHSVTDYRSLIPSDEETTIPDDDESGSTSRIRPRLTPRPAQSVLSDGLSQASRRASKYRRSMSGIPNLQETLKERQARFREARENRRMRIDSLYKYIFEILAEKIGLDIPTVEELILDCPSLDPFSKFFEKGGCKTLKFFYQEGDAPGLESGRTITGVPKGTKMMRLYIDSAAPEKLKGLCMFFVRCRNEVAINAKNIYEDVLFTVLDASKGLLKGIRNMLQYIFLPAILATNNWGALNQSKQGESEKHIFTETINRYLSFLDGARISIEGTVMLKKVDNIDFSKLHTFEEVTAAASNSEMLHQLEEVLMMWYKQIEQVLIESEQMRKEADDSGPLTELEHWKRMSAKFNYIIEQIKGSSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLEKVCQPLYNYDLVSMAHGIQNLINAIRMIHSVSRYYNTSERMTSLFIKVTNQMVTACKAYITDGGTNHVWDQETPAVLKKIQDCIFLFKEYQASFHKTRKQILESSGEKSFEVSEMYIFGKFEAFCKRLEKIKEMITIVQTYSALSNSTIEGIDIMAIKFKNIYQGIKKNQYDILDPRRTEFDTDFSDFMSKINSLEIQIQGFMNSTFGKILSSQQALQLLQRFQKLNIPCLQLEITHTIERILQCYVAELEATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRIHEPINYFFKNSEILSSAEGKAVIRQYNKISYVLVEFEVVYHMAWVKEISQLQYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDDLCQEVPSVFVNLMTPRMKKVESVLRQGLTILTWSSLMLESFFHEVEFVLDMFNQLLKKINDLCEMHIDTVLKEIAKTLLISLPDSGATRVEDMLTLNETYTREWADVLNHKSRHVEEAVKELILIFEQIYEVKYTGKAAKAVPEQRKHVVFGSETEEADSLEYEPESKEVETNDKEDEFKKECKEVYAFFSHQLLDSLQKATRLSLDTMKKRIFVGSLGRKRSEDIVSFIKTEVHLAIPNVVMVPSLDDIQQAINRMIQFTLEVSRGVAHWGQQQVRRIKSIPNSSSRTDQNLPGTGKVLLKEDRSYEETIPARKLKNFYPGVAEHKDISKLVLLLSSSMNSLRKAANEALQDFQKYKTLWTEDRDVKVKEFLANNPSLTEIRSEILHYATFEQEIDELKPIIVVGALELHTEPMKLALSIEAKAWKMLLCRYLNEEYKKKMSDMIAFITEYLKKLSRPIRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYGILNRFEVEVTKEESEGVDTLRYSFNKLQSKAVSVQDELVQVQPKFKGNLLESVEIFREDVVNFTEAYELEGPMVPNIPPQEASNRLQIFQANFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKIRKELNLLQKLYGLYDTVMGSISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKNKDDIEDICISASKEKDIEAKLTQVVENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVISCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRMMAVISREGEKIMLDTPVMAKGPVEIWLLDLLKVQMSSLHNIIRSAFYQISDSGFLLLPFLHHFPAQVGLLGIQMLWTHDSEEALNNAKDDRKIMQITNQKFLDILNTLISQTTHDLTKFDRVKFETLITIHVHQRDIFDDLVKMHIKSVTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKILFRTVAMMVPDRQIIMRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSTVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSSTYAELQAAVDNQVNLEGLINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTAVITILMKSLTECGRPHREMRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKLLFEVHNIENASPATVSRMGMVYISSSALNWRPILQAWLKKRTQQEASVFLSLYDKAFEETYTYMKLTLNPKMQLLECNYIMQSLNLLEGLIPSKEEGGISSMDHLHKLFVFGLMWSLGALLELESREKLELFLRGHKSKLDLPEIPKDTHQTMYEFFVSDIGDWEHWNKRLQPYFYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQHKAVLLTGEQGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRMGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNTSIDKIFGIIGCGYFDPCRKFKPEICEMVGNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECDSITILMSLFKHECHRVIADRFITPEDEQWFDAQLIRAIEENISPDIASVLLPEPYFVDFLRDMPEITGDEPEDTAFEVPKIYELVPTFEYLSEKLQFYQKQFNEIIRGTTLDLVFFKDAMTHLIKISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVANLIDDLKNLYKVAGAEGKGITFIFTDNEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFDNLYEYFISRSRRNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPKEALIAVASYFLLEYNIVCSTEIKKQVVETMGLFHDMVSESCENYFQRYRRRAHVTPKSYLSFINGYKNIYTEKVKYINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASVKADEVLAEVTVSAQASAKVKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKPCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMEDYSFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDDAMNEKMDLLNDADMCRKKMQAASTLIDGLSGEKVRWTQQSKEFKAQINRLVGDVLLCTGFLSYLGPFNQIFRNYLLKDQWELELKARKIPFTENLNLIAMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIREELDPALDNVLEKNFIKSGTAFKVKVGDKECDVMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELESERVKLLEDVTFNKRKMKELEDNLLYKLSTTQGSLVDDESLIGVLHITKHTAAEVSEKLHVAAETEIKINTAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKPFRWILDMTWLNLVELSKLPQFAEIMNQISRNEKGWKNWFDKDAPEEEIIPDGYNDSLDTCRKLLLIRSWCPDRTVFQARKYIADSLEDKYTEPVILNLEKTWEESDTHTPLICFLSMGSDPTIQIDALAKKLKLECRTISMGQGQEVHARKLVQMSMLQGGWVLLQNCHLGLEFMEELLETLMTTETMEDSFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLDISNLPMWKPMLYTVAFLHSTVQERRKFGPLGWNIPYEFNSADFTASVQFIQNHLDECDIKKGVSWSTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEPSFCFYTGYKIPVCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLDTITNIQPKESGGGMGETREAIVYRLSEDMLSKLPPDYVPHEVKARLVKMGHLNSMNIFLRQEIDRMQRVISILRNSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVSWDSSTLGFWFTELLERNAQFSVWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITAPPVEGVYIYGLYMDGASWDRRNGKLTESTPKVLFMQIPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDLTFITMVYLRTVLSPDHWILRGVALLCDIK", "length": 4730, "header": "tr|A0A9J7HD26-1|A0A9J7HD26_CRIGR Isoform 1 of Dynein heavy chain 8, axonemal isoform X2 OS=Cricetulus griseus OX=10029 GN=Dnah8 PE=3 SV=1 CANONICAL=A0A9J7HD26-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3278, "start_aa": "Thr", "end_pos": 3278, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3278", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 72, "start_aa": "Thr", "end_pos": 72, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr72", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD26" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD26" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763108", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763108", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD26" } ], "pmid": "" }, { "name": "minus-end-directed microtubule motor activity", "id": "GO:0008569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008569", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD26" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD26" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD26" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD26" } ], "pmid": "" }, { "name": "axonemal dynein complex", "id": "GO:0005858", "url": 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This record is derived from a genomic sequence (NW_023277424.1) annotated using gene prediction method: Gnomon. 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Classification" ] }, { "id": "113838676", "url": "https://www.ncbi.nlm.nih.gov/gene/113838676", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113838676", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838676", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HD44", "url": "https://www.orthodb.org/?gene=A0A9J7HD44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309820", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309820", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HD44", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HD44-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEYKLVVVGADGVGKSALTIQLIQNLFVDEYDPTIEDSYRKQVVIDREICHLDILDTAGLEEYSAMSDQYMRTGEGFLCVFAMNNTKSFEAIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGRVKIKKCIVM", "length": 189, "header": "tr|A0A9J7HD44-1|A0A9J7HD44_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113838676 PE=3 SV=1 CANONICAL=A0A9J7HD44-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HD44-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD44/entry#A0A9J7HD44-1", "sequence": { "sequence": "MSEYKLVVVGADGVGKSALTIQLIQNLFVDEYDPTIEDSYRKQVVIDREICHLDILDTAGLEEYSAMSDQYMRTGEGFLCVFAMNNTKSFEAIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGRVKIKKCIVM", "length": 189, "header": "tr|A0A9J7HD44-1|A0A9J7HD44_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113838676 PE=3 SV=1 CANONICAL=A0A9J7HD44-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "cge:113838676", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838676", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD44", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD44" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD44", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD44" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD44", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD44" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD44", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRJ8-1", "G3GY22-1", "G3H2D6-1", "G3HID1-1", "A0A9J7FY79-1", "G3IBI0-1", "G3HIM4-1", "G3HLW5-1", "G3I0B0-1", "G3H8L7-1", "G3IMU0-1", "G3HQ45-1", "G3HX83-1", "G3H515-1", "G3HRK4-1", "G3HWS3-1", "G3I185-1", "G3I2E9-1", "G3IHJ9-1", "G3I5Q9-1", "G3H3P1-1", "G3HGA7-1", "A0A9J7K0Q7-1", "G3I8B8-1", "A0A9J7FPY4-1", "A0A9J7JNI7-1", "A0A9J7JTM0-1", "G3HXK0-1", "G3I1T6-1", "A0A8C2M8V3-1", "G3HAT4-1", "G3HBU1-1", "A0A8C2MG78-1", "A0A9J7JFJ5-1", "A0A061I5F7-1", "A0A9J7GMX4-1", "G3H3X0-1", "A0A8C2MG41-1", "A0A8C2MJU2-1", "A0A8C2MKJ3-1", "A0A8C2QMP3-1", "A0A9J7F720-1", "A0A061IFE4-1", "A0A061HZZ7-1", "A0A8C2M6H7-1", "A0A8C2M9W6-1", "A0A9J7H2L4-1", "A0A8C2MH13-1", "A0A8C2MMV7-1", "A0A8C2MPE2-1", "A0A8C2LL65-1", "A0A3L7HXE9-1", "A0A8C2LGZ8-1", "A0A8C2LIB5-1", "A0A8C2LNU7-1", "A0A9J7JYH7-1", "A0A8C2LV21-1", "A0A9J7GDV9-1", "A0A8C2QEY0-1", "A0A9J7FVQ6-1", "A0A9J7K0X9-1", "A0A9J7J7P8-1", "A0A8C2M2X0-1", "A0A8C2MAV7-1", "A0A8C2MQL3-1", "A0A3L7HA69-1", "A0A8C2LLE7-1", "A0A061HWM0-1", "A0A061I5K5-1", "A0A061IH58-1", "A0A061INW8-1", "A0A3L7GXQ2-1", "A0A9J7GN19-1", "A0A3L7HQ44-1", "A0A3L7IA35-1", "A0A3L7IMK5-1", "A0A8C2LIE2-1", "A0A9J7GAZ9-1", "A0A9J7HCG9-1", "A0A9J7HC46-1", "A0A9J7HC79-1", "A0A9J7HCE0-1", "A0A9J7JRE1-1", "A0A9J7GJ78-1", 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF00969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307322", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307322", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HD48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HD48-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD48-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMGPWLPRRSCVAAVVPTLMALSPRVALVRARFLQQVKSECHFSNGTERVWYLQRHIYNQEEHLRFDSKMGKYQAVTKLGKIQAEYWNSQEGFLEQKRAKVDTFCRFNYAIVGLLTVLQRAEPRVTVYLTKTQPLEHRNLLVCSVSGFYPGHIEVRWFQNDQEEKAGIVSTGLIRNGDWTFQILVMLETVPQSGEVYTCQVEHPSLTSPVTVEWRAQSTSAQNKMLSGIGGFVLGLLFFWLGLFIYFRNQKGWLHPGPQAAPRMDCLLVTRLDPSTVHTLVPRMVLFIRSTCLSLWRPTCLSHLSVTLEAHLSVPPVCHLEAHLSVTLEAHLSVTLEAHLSVTLEAHLSVTLEAHLSVTLEAHLSVTLEIHLSVTLEAHQSVTLEAHLSVTLEAHLSVTLEAHLSVTL", "length": 408, "header": "tr|A0A9J7HD48-1|A0A9J7HD48_CRIGR Isoform 1 of H-2 class II histocompatibility antigen, E-S beta chain isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100750512 PE=3 SV=1 CANONICAL=A0A9J7HD48-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HD48-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD48/entry#A0A9J7HD48-1", "sequence": { "sequence": "MMGPWLPRRSCVAAVVPTLMALSPRVALVRARFLQQVKSECHFSNGTERVWYLQRHIYNQEEHLRFDSKMGKYQAVTKLGKIQAEYWNSQEGFLEQKRAKVDTFCRFNYAIVGLLTVLQRAEPRVTVYLTKTQPLEHRNLLVCSVSGFYPGHIEVRWFQNDQEEKAGIVSTGLIRNGDWTFQILVMLETVPQSGEVYTCQVEHPSLTSPVTVEWRAQSTSAQNKMLSGIGGFVLGLLFFWLGLFIYFRNQKGWLHPGPQAAPRMDCLLVTRLDPSTVHTLVPRMVLFIRSTCLSLWRPTCLSHLSVTLEAHLSVPPVCHLEAHLSVTLEAHLSVTLEAHLSVTLEAHLSVTLEAHLSVTLEAHLSVTLEIHLSVTLEAHQSVTLEAHLSVTLEAHLSVTLEAHLSVTL", "length": 408, "header": "tr|A0A9J7HD48-1|A0A9J7HD48_CRIGR Isoform 1 of H-2 class II histocompatibility antigen, E-S beta chain isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100750512 PE=3 SV=1 CANONICAL=A0A9J7HD48-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD48" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD48" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750512", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750512", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "MHC class II protein complex", "id": "GO:0042613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042613", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD48" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD48" } ], "pmid": "" }, { "name": "antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "id": "GO:0002504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002504", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD48" }, { "id": "PS50835", "database": "PROSITE", "url": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"LOC113838326", "type": "recommended", "evidence": [ { "id": "A0A9J7HD53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD53" } ] }, { "name": "LOC113838326", "type": "synonym", "evidence": [ { "id": "XP_035309470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309470" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A9J7HD53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD53/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A9J7HD53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD53/entry#names_and_taxonomy" } ] }, { "name": "GTPase KRas-like", "type": "synonym", "evidence": [ { "id": "XP_035309470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309470" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309470", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309470" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HD53", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD53" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113838326", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD53", "locus": {} } ], "crossref": [ { "id": "A0A9J7HD53", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HD53", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04138", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04138", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113838326", "url": "https://www.ncbi.nlm.nih.gov/gene/113838326", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113838326", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838326", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HD53", "url": "https://www.orthodb.org/?gene=A0A9J7HD53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309470", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309470", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HD53", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HD53-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEYKLVVVGADGVGKTALTIQLIQYHFVDVYDPTIEDSYRKQVEIDGEICHLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAMNNTKSFEAIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLAGIYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGRVKIKKCTVM", "length": 189, "header": "tr|A0A9J7HD53-1|A0A9J7HD53_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113838326 PE=3 SV=1 CANONICAL=A0A9J7HD53-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HD53-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HD53/entry#A0A9J7HD53-1", "sequence": { "sequence": "MTEYKLVVVGADGVGKTALTIQLIQYHFVDVYDPTIEDSYRKQVEIDGEICHLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAMNNTKSFEAIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLAGIYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGRVKIKKCTVM", "length": 189, "header": "tr|A0A9J7HD53-1|A0A9J7HD53_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113838326 PE=3 SV=1 CANONICAL=A0A9J7HD53-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], 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automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. 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"MRELLEREEEFNFLLGKNDILKQVTEQCDVCARVNASRLKLPPGNRVRGYRPGTHWEIDFTEIKPGKYGYKYLLFFLDTFSGWVEAVPTKHETAKIVTKKLLEEIFPRYGMPQVLGTDNGPAFVSQVSQSVATLLGIDWKLHCAYRPQSSGQVERMNRTIKETLTKLSLTTGTRDWVLLLPLTLYCARNTPGLHGLTPFEILYGVPTPIINFLDQDVSDFANSPSLQAHLQALQLVQQEVWKPLAQAYKDQRDHPAIPHSYQIGDTVWVRRHQTKNLEPRWKGPYIVLLTTPTALKVDGIAAWIYASHVKPARPTDSATASEWTAHGTQNPLKIRLSPTSPHTIHALTWQVLSQTGEVIYETTKNHALGIWWPTLTPDFCDLVAGLDIWDISHCYPKACSNGNDLPRMRRSLQSXRETTPGYSSQWAKDQLSGKDFYVCPRDGRAWKQTQTCGGHGQFFCAAWGCETTGDAYWKPSSSWDKIQVTRGWQKGSTGTTSMPLLISFTDKGKKATEWQKGYVWGFRWYLSGPDRGAIFKIRLKIETITKTIGPNPVLTDQKPPTKPHGFRPHRPLPHLPPSPTPSSKTTTLTVKTPVHIPTSPYPGTGDRLLELIQGAYLALNFSDPSKTQXCWLCLVSQPPYYEDVAVLGNYSNQTSAPTNCGTAMQHKLTLSEVSGKGLCIGRVPPSYQELCNQVEPLSQDSRYLVAPYGTYWACSTGLTPCVSTTILNATTDFCILTELWPRVTYHQPEYVYMILEKSTRHQREPMSLTVALLLGGITMGGIAAGIGTGTVALQETSHFKLLQQAMHTDIQALEESVSALEKSLTSLSEVVLQNRRGLDLLFLQEGGLCAALKEECCFYADHTGIVRDSMAKLRERLKQRQQLFESQQGWFEGWFAKSPWFTTLISTLMGPLVILFLILIFGPCILNKMTQFIRERLSVVQALVLTQQYHQLKQIDLEYPETSE", "length": 964, "header": "tr|A0A9J7HDP2-1|A0A9J7HDP2_CRIGR Isoform 1 of LOW QUALITY PROTEIN: uncharacterized protein LOC113839223 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC113839223 PE=4 SV=1 CANONICAL=A0A9J7HDP2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HDP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDP2/entry#A0A9J7HDP2-1", "sequence": { "sequence": "MRELLEREEEFNFLLGKNDILKQVTEQCDVCARVNASRLKLPPGNRVRGYRPGTHWEIDFTEIKPGKYGYKYLLFFLDTFSGWVEAVPTKHETAKIVTKKLLEEIFPRYGMPQVLGTDNGPAFVSQVSQSVATLLGIDWKLHCAYRPQSSGQVERMNRTIKETLTKLSLTTGTRDWVLLLPLTLYCARNTPGLHGLTPFEILYGVPTPIINFLDQDVSDFANSPSLQAHLQALQLVQQEVWKPLAQAYKDQRDHPAIPHSYQIGDTVWVRRHQTKNLEPRWKGPYIVLLTTPTALKVDGIAAWIYASHVKPARPTDSATASEWTAHGTQNPLKIRLSPTSPHTIHALTWQVLSQTGEVIYETTKNHALGIWWPTLTPDFCDLVAGLDIWDISHCYPKACSNGNDLPRMRRSLQSXRETTPGYSSQWAKDQLSGKDFYVCPRDGRAWKQTQTCGGHGQFFCAAWGCETTGDAYWKPSSSWDKIQVTRGWQKGSTGTTSMPLLISFTDKGKKATEWQKGYVWGFRWYLSGPDRGAIFKIRLKIETITKTIGPNPVLTDQKPPTKPHGFRPHRPLPHLPPSPTPSSKTTTLTVKTPVHIPTSPYPGTGDRLLELIQGAYLALNFSDPSKTQXCWLCLVSQPPYYEDVAVLGNYSNQTSAPTNCGTAMQHKLTLSEVSGKGLCIGRVPPSYQELCNQVEPLSQDSRYLVAPYGTYWACSTGLTPCVSTTILNATTDFCILTELWPRVTYHQPEYVYMILEKSTRHQREPMSLTVALLLGGITMGGIAAGIGTGTVALQETSHFKLLQQAMHTDIQALEESVSALEKSLTSLSEVVLQNRRGLDLLFLQEGGLCAALKEECCFYADHTGIVRDSMAKLRERLKQRQQLFESQQGWFEGWFAKSPWFTTLISTLMGPLVILFLILIFGPCILNKMTQFIRERLSVVQALVLTQQYHQLKQIDLEYPETSE", "length": 964, "header": "tr|A0A9J7HDP2-1|A0A9J7HDP2_CRIGR Isoform 1 of LOW QUALITY PROTEIN: uncharacterized protein LOC113839223 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC113839223 PE=4 SV=1 CANONICAL=A0A9J7HDP2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 580, "start_aa": "Thr", "end_pos": 580, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr580", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "cge:113839223", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113839223", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDP2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDP2" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDP2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDP2" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDP2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDP2" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDP2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDP2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDP2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 620, "end_pos": 622, "annotation": "n_glycosylation_sequon" }, { "start_pos": 649, "end_pos": 651, "annotation": "n_glycosylation_sequon" }, { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" }, { "start_pos": 728, "end_pos": 730, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"start_pos": 728, "end_pos": 730 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A9J7HDQ0-1", "uniprot_ac": "A0A9J7HDQ0", "uniprot_id": "A0A9J7HDQ0_CRIGR", "mass": { "chemical_mass": 10345.0, "monoisotopic_mass": 10345.0 }, "refseq": { "ac": "XP_035309839", "name": "ubiquitin-60S ribosomal protein L40-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309839" }, "gene_names": [ { "name": "LOC118239831", "type": "recommended", "evidence": [ { "id": "A0A9J7HDQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDQ0" } ] }, { "name": "LOC118239831", "type": "synonym", "evidence": [ { "id": "XP_035309839", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309839" } ] } ], "protein_names": [ { "name": "Ubiquitin-ribosomal protein eL40 fusion protein", "type": "recommended", "evidence": [ { "id": "A0A9J7HDQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDQ0/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin A-52 residue ribosomal protein fusion product 1", "type": "synonym", "evidence": [ { "id": "A0A9J7HDQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDQ0/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-60S ribosomal protein L40-like", "type": "synonym", "evidence": [ { "id": "XP_035309839", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309839" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 100% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277442.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309839", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309839" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDQ0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC118239831", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDQ0", "locus": {} } ], "crossref": [ { "id": "A0A9J7HDQ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HDQ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "118239831", "url": "https://www.ncbi.nlm.nih.gov/gene/118239831", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001975", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001975", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:118239831", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239831", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HDQ0", "url": "https://www.orthodb.org/?gene=A0A9J7HDQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10666", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10666", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309839", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309839", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HDQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEIFNKFLQGKTITLEVQPSDFMDNVKTKTQDKEGISPDHHIIEPSLCQSLQKDKYDKAMLCCPHLHLCVVNFLEKKGGHTNNLHPKKIK", "length": 90, "header": "tr|A0A9J7HDQ0-1|A0A9J7HDQ0_CRIGR Isoform 1 of Ubiquitin-ribosomal protein eL40 fusion protein OS=Cricetulus griseus OX=10029 GN=LOC118239831 PE=3 SV=1 CANONICAL=A0A9J7HDQ0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HDQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDQ0/entry#A0A9J7HDQ0-1", "sequence": { "sequence": "MEIFNKFLQGKTITLEVQPSDFMDNVKTKTQDKEGISPDHHIIEPSLCQSLQKDKYDKAMLCCPHLHLCVVNFLEKKGGHTNNLHPKKIK", "length": 90, "header": "tr|A0A9J7HDQ0-1|A0A9J7HDQ0_CRIGR Isoform 1 of Ubiquitin-ribosomal protein eL40 fusion protein OS=Cricetulus griseus OX=10029 GN=LOC118239831 PE=3 SV=1 CANONICAL=A0A9J7HDQ0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307678", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307678" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDQ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDQ4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Anks1a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDQ4", "locus": {} } ], "crossref": [ { "id": "A0A9J7HDQ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HDQ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01274", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01274", "database": "CDD", "categories": [ "Protein Classification" ] 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Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027243952", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243952" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6I3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6I3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Myo1g", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6I3", "locus": {} } ], "crossref": [ { "id": "A0A9J7J6I3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J6I3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01378", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01378", "database": "CDD", "categories": [ "Protein Classification" ] }, 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDU4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDU4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDU4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDU4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766313", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766313", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6I3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6I3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6I3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6I3" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6I3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6I3" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6I3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6I3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J6I3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6I3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308934" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HDZ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDZ3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100757064", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDZ3", "locus": {} } ], "crossref": [ { "id": "100757064", "url": "https://www.ncbi.nlm.nih.gov/gene/100757064", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757064", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757064", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HDZ3", "url": "https://www.orthodb.org/?gene=A0A9J7HDZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23145", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23145", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23145:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23145:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01101", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01101", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308934", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HDZ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HDZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEIQKEHCDEIALNPIRTVGIRTTQNRTAEMTYWTTALAVKSDNLNLVPKSHLDLLRRAATTPQRKAAGDASQEPKRRSARLCAMPVPFTPEVKPTRTSTPKKLKTSNVIVEENKDVGAVTIPETKPEDVKEECNVENAENGEAKIIEAPIPKMETEEIKEQMNEDAEEVRGEENEAVAAEGKDDEVEENIEKDEDGKEDGDKGEDGNRDAIPGEKADSAESEDEKEDKDDEEKGGDEKEGVKXEGYGKKXEEKDDKEEKAEVEEEVEEQKEEKEEEDRKCKEEENKEDGEGQSEEDGKEKDDGKEEDRKEEEGKGKEVAGGGNDENKVEAEKEAENKDFKQDEKRRSL", "length": 349, "header": "tr|A0A9J7HDZ3-1|A0A9J7HDZ3_CRIGR Isoform 1 of LOW QUALITY PROTEIN: high mobility group nucleosome-binding domain-containing protein 5-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100757064 PE=3 SV=1 CANONICAL=A0A9J7HDZ3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HDZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HDZ3/entry#A0A9J7HDZ3-1", "sequence": { "sequence": "MEIQKEHCDEIALNPIRTVGIRTTQNRTAEMTYWTTALAVKSDNLNLVPKSHLDLLRRAATTPQRKAAGDASQEPKRRSARLCAMPVPFTPEVKPTRTSTPKKLKTSNVIVEENKDVGAVTIPETKPEDVKEECNVENAENGEAKIIEAPIPKMETEEIKEQMNEDAEEVRGEENEAVAAEGKDDEVEENIEKDEDGKEDGDKGEDGNRDAIPGEKADSAESEDEKEDKDDEEKGGDEKEGVKXEGYGKKXEEKDDKEEKAEVEEEVEEQKEEKEEEDRKCKEEENKEDGEGQSEEDGKEKDDGKEEDRKEEEGKGKEVAGGGNDENKVEAEKEAENKDFKQDEKRRSL", "length": 349, "header": "tr|A0A9J7HDZ3-1|A0A9J7HDZ3_CRIGR Isoform 1 of LOW QUALITY PROTEIN: high mobility group nucleosome-binding domain-containing protein 5-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100757064 PE=3 SV=1 CANONICAL=A0A9J7HDZ3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE04" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761763", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761763", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "mRNA regulatory element binding translation repressor activity", "id": "GO:0000900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000900", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HE04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE04" } ], "pmid": "" }, { "name": "translation factor activity, RNA binding", "id": "GO:0008135", "url": 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Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF248", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF248", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08374", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08374", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309295", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309295", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HEA5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HEA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K4R3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K4R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4R3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KET6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KET6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KET6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KET6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFU3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFNREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSILNDNENFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKALHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIVAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQCNSHNKSDNIPVTHQKCPSSTGFHIRENEESHSESQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDTNRNQFNDRKQYSSNEGHFNNGSHMADIPLANLKSYKQAGGTIESPKEHQL", "length": 1237, "header": "tr|A0A9J7HEA5-1|A0A9J7HEA5_CRIGR Isoform 1 of Protocadherin-9 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pcdh9 PE=4 SV=1 CANONICAL=A0A9J7HEA5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HEA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEA5/entry#A0A9J7HEA5-1", "sequence": { "sequence": "MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFNREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSILNDNENFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKALHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIVAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQCNSHNKSDNIPVTHQKCPSSTGFHIRENEESHSESQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDTNRNQFNDRKQYSSNEGHFNNGSHMADIPLANLKSYKQAGGTIESPKEHQL", "length": 1237, "header": "tr|A0A9J7HEA5-1|A0A9J7HEA5_CRIGR Isoform 1 of Protocadherin-9 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pcdh9 PE=4 SV=1 CANONICAL=A0A9J7HEA5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K4R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEA5/entry#A0A9J7K4R3-1", "sequence": { "sequence": "MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFNREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSILNDNENFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKALHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIVAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQSQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDTNRNQFNDRKQYSSNEGHFNNGSHMADIPLANLKSYKQAGGTIESPKEHQL", "length": 1203, "header": "tr|A0A9J7K4R3-1|A0A9J7HEA5_CRIGR Computationally mapped isoform of Protocadherin-9 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pcdh9 PE=4 SV=1 CANONICAL=A0A9J7HEA5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KET6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEA5/entry#A0A9J7KET6-1", "sequence": { "sequence": "MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFNREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSILNDNENFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKALHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIVAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDTNRNQFNDRKQYSSNEGHFNNGSHMADIPLANLKSYKQAGGTIESPKEHQL", "length": 1161, "header": "tr|A0A9J7KET6-1|A0A9J7HEA5_CRIGR Computationally mapped isoform of Protocadherin-9 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pcdh9 PE=4 SV=1 CANONICAL=A0A9J7HEA5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KFU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEA5/entry#A0A9J7KFU3-1", "sequence": { "sequence": "MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFNREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSILNDNENFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKALHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIVAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQCNSHNKSDNIPVTHQKCPSSTGFHIRENEESHSEPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDTNRNQFNDRKQYSSNEGHFNNGSHMADIPLANLKSYKQAGGTIESPKEHQL", "length": 1195, "header": "tr|A0A9J7KFU3-1|A0A9J7HEA5_CRIGR Computationally mapped isoform of Protocadherin-9 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pcdh9 PE=4 SV=1 CANONICAL=A0A9J7HEA5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K4R3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4R3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K4R3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4R3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768906", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768906", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEA5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEA5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEA5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEA5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEA5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1017, "end_pos": 1019, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1207, "end_pos": 1209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 754, "end_pos": 756, "annotation": "n_glycosylation_sequon" }, { "start_pos": 775, "end_pos": 777, "annotation": "n_glycosylation_sequon" }, { "start_pos": 780, "end_pos": 782, "annotation": "n_glycosylation_sequon" }, { "start_pos": 901, "end_pos": 903, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308848", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308848" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEE3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100774072", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEE3", "locus": {} } ], "crossref": [ { "id": "A0A9J7HEE3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HEE3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05059", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05059", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10398", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10398", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11907", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11907", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774072", "url": "https://www.ncbi.nlm.nih.gov/gene/100774072", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774072", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774072", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HEE3", "url": "https://www.orthodb.org/?gene=A0A9J7HEE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24418", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24418", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308848", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308848", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HEE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HEE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISFSDSNFQSVLCCCCCCSVQKRQVRTQISLSKNEEPSENYSQHRRPWLDKLKSKKHSNRGGAQPSKRKPLPPLPLAQLAEERIQVKALYDFLPREPCNLALKRAEEYLILERCDPHWWKARDRLGNEGLIPSNYVTENRVTNLEIYEWYHKNITRNQTERLLRQEAKEGAFIVRDSRHLGSYTISVFTRAGRSTQSSVKHYQIKKNDSGQWYVAERHLFPSVPELIQYHQYNAAGLMSRLRYPVGLLGSCLPATAGFSYEKWEIDPSELAFIKEVGSGQFGVVHLGEWRAHIRVAIKAINEGFMSEEDFIEEAKVMMKLSHSRLVQLYGVCIQHKPLYIVTEFMENGCLLNYLRERKGKLPKPLLLSVCQDICEGMEYLEKNCYIHRDLAARNCLVSSTCVVKISDFGMTRYVLDDEYISSSGAKFPVKWSPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISNGFRLYRPHLAPMSIYGVMYSCWHENPKGRPTFAELLQVLTEIAETW", "length": 527, "header": "tr|A0A9J7HEE3-1|A0A9J7HEE3_CRIGR Isoform 1 of Tyrosine-protein kinase OS=Cricetulus griseus OX=10029 GN=LOC100774072 PE=3 SV=1 CANONICAL=A0A9J7HEE3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HEE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEE3/entry#A0A9J7HEE3-1", "sequence": { "sequence": "MISFSDSNFQSVLCCCCCCSVQKRQVRTQISLSKNEEPSENYSQHRRPWLDKLKSKKHSNRGGAQPSKRKPLPPLPLAQLAEERIQVKALYDFLPREPCNLALKRAEEYLILERCDPHWWKARDRLGNEGLIPSNYVTENRVTNLEIYEWYHKNITRNQTERLLRQEAKEGAFIVRDSRHLGSYTISVFTRAGRSTQSSVKHYQIKKNDSGQWYVAERHLFPSVPELIQYHQYNAAGLMSRLRYPVGLLGSCLPATAGFSYEKWEIDPSELAFIKEVGSGQFGVVHLGEWRAHIRVAIKAINEGFMSEEDFIEEAKVMMKLSHSRLVQLYGVCIQHKPLYIVTEFMENGCLLNYLRERKGKLPKPLLLSVCQDICEGMEYLEKNCYIHRDLAARNCLVSSTCVVKISDFGMTRYVLDDEYISSSGAKFPVKWSPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISNGFRLYRPHLAPMSIYGVMYSCWHENPKGRPTFAELLQVLTEIAETW", "length": 527, "header": "tr|A0A9J7HEE3-1|A0A9J7HEE3_CRIGR Isoform 1 of Tyrosine-protein kinase OS=Cricetulus griseus OX=10029 GN=LOC100774072 PE=3 SV=1 CANONICAL=A0A9J7HEE3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KFE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEE3/entry#A0A9J7KFE9-1", "sequence": { "sequence": "MISFSDSNFQSVLCCCCCCSVQKRQVRTQISLSKNEEPSENYSQHRRPWLDKLKSKKHSNRGGAQPSKRKPLPPLPLAQLAEERIQVKALYDFLPREPCNLALKRAEEYLILERCDPHWWKARDRLGWYHKNITRNQTERLLRQEAKEGAFIVRDSRHLGSYTISVFTRAGRSTQSSVKHYQIKKNDSGQWYVAERHLFPSVPELIQYHQYNAAGLMSRLRYPVGLLGSCLPATAGFSYEKWEIDPSELAFIKEVGSGQFGVVHLGEWRAHIRVAIKAINEGFMSEEDFIEEAKVMMKLSHSRLVQLYGVCIQHKPLYIVTEFMENGCLLNYLRERKGKLPKPLLLSVCQDICEGMEYLEKNCYIHRDLAARNCLVSSTCVVKISDFGMTRYVLDDEYISSSGAKFPVKWSPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISNGFRLYRPHLAPMSIYGVMYSCWHENPKGRPTFAELLQVLTEIAETW", "length": 505, "header": "tr|A0A9J7KFE9-1|A0A9J7HEE3_CRIGR Computationally mapped isoform of Tyrosine-protein kinase OS=Cricetulus griseus OX=10029 GN=LOC100774072 PE=3 SV=1 CANONICAL=A0A9J7HEE3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFE9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFE9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774072", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774072", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEE3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEE3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEE3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3HE98-1", "Q63980-1", "G3HAZ9-1", "G3IFY3-1", "G3GY19-1", "G3GYQ3-1", "G3H552-1", "G3HQK4-1", "G3HQP4-1", "G3HVB0-1", "G3IG17-1", "A0A9J7GY37-1", "G3H0L5-1", "G3GVI7-1", "G3HGZ0-1", "G3HGZ1-1", "G3HY52-1", "G3HEH4-1", "A0A9J7FB39-1", "G3IIC0-1", "A0A8C2QBZ6-1", "A0A9J7EY99-1", "A0A9J7FT87-1", "A0A9J7G180-1", "A0A8C2MTI7-1", "A0A8C2N3H2-1", "A0A9J7K5K0-1", "A0A8C2LY52-1", "A0A8C2MDG3-1", "A0A8C2QJN6-1", "A0A8C2MCF8-1", "A0A8C2MPY4-1", "A0A8C2QMK6-1", "A0A8C2N9X1-1", "A0A9J7KFV4-1", "A0A9J7EUZ9-1", "A0A9J7F492-1", "A0A8C2LIN5-1", "A0A9J7F1W8-1", "A0A9J7F4U9-1", "A0A9J7FIT0-1", "A0A9J7FX84-1", "A0A8C2MH43-1", "A0A9J7G9F9-1", "A0A9J7GHS8-1", "A0A9J7GVQ2-1", "A0A8C2MAM4-1", "A0A9J7H847-1", "A0A9J7H9K9-1", "A0A9J7HE43-1", "A0A061I765-1", "A0A061IKX8-1", "A0A8C2M5A7-1", "A0A9J7K378-1", "A0A8C2MJB3-1", "A0A9J7F773-1", "A0A8C2LKN1-1", "A0A9J7JQV6-1", "A0A9J7K3R5-1", "A0A9J7K8D7-1", "A0A9J7KAA7-1", "A0A8C2MV78-1", "A0A8C2N756-1", "A0A9J7KBU9-1", "A0A8C2QPB0-1", "A0A9J7F6S3-1", "A0A9J7FEZ2-1", "A0A9J7FS53-1", "A0A9J7FUX7-1", "A0A9J7FZG2-1", "A0A9J7FZH7-1", "A0A9J7G654-1", "A0A8C2QLE7-1", "A0A9J7GBI2-1", "A0A9J7GHB3-1", "A0A9J7GIN7-1", "A0A9J7GJW5-1", "A0A9J7GMF3-1", "A0A9J7GSH6-1", "A0A8C2MTN3-1", "A0A9J7JZS0-1", "A0A8C2M187-1", "A0A9J7GT89-1", "A0A9J7GVJ0-1", "A0A9J7GYA4-1", "A0A9J7H167-1", "A0A9J7H923-1", "A0A9J7JLX1-1", "A0A8C2LP31-1", "A0A8C2QHC0-1", "A0A8C2LWB2-1", "A0A9J7G398-1", "A0A8C2N659-1", "A0A9J7JTY4-1", "A0A9J7GP54-1", "A0A9J7K499-1", "A0A9J7HEE3-1", "A0A061IJA8-1", "A0A061IR93-1", "A0A8C2LLJ5-1", "A0A8C2M0D7-1", "A0A8C2M0T0-1", "A0A8C2M8I7-1", "A0A8C2N2G1-1", "A0A8C2N2R2-1", "A0A9J7G2Q4-1", "A0A8C2LHA9-1", "A0A8C2M4P9-1", "A0A9J7F8T9-1", "A0A9J7GLP2-1", "A0A9J7GRN1-1", "A0A3L7HKL8-1", "A0A8C2L7Q1-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061I765", "gene_name": "Wee1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I765", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I765" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061I765", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I765" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IKX8", "gene_name": "Epha7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IKX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IKX8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A061IKX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IKX8" } ] } ] }, { "uniprot_ac": "A0A061IR93", "gene_name": "Kdr", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IR93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IR93" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A061IR93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IR93" } ] } ] }, { "uniprot_ac": "A0A3L7HKL8", "gene_name": "Pkdcc", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKL8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7HKL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKL8" } ] } ] }, { "uniprot_ac": "A0A8C2L7Q1", "gene_name": "Alk", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ 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{ "uniprot_ac": "A0A8C2QHC0", "gene_name": "Fyn", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHC0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2QHC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHC0" } ] } ] }, { "uniprot_ac": "A0A8C2QJN6", "gene_name": "Tie1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJN6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8C2QJN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJN6" } ] } ] }, { "uniprot_ac": "A0A8C2QLE7", "gene_name": "Mertk", 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"L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] } ] }, { "uniprot_ac": "A0A9J7EUZ9", "gene_name": "Fgfr3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EUZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUZ9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7EUZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUZ9" } ] } ] }, { "uniprot_ac": "A0A9J7EY99", "gene_name": "Epha1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EY99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY99" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7EY99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY99" } ] } ] }, { "uniprot_ac": "A0A9J7F1W8", "gene_name": "Met", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F1W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1W8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7F1W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1W8" } ] } ] }, { "uniprot_ac": "A0A9J7F492", "gene_name": "Kit", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F492", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F492" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7F492", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F492" } ] } ] }, { "uniprot_ac": "A0A9J7F4U9", "gene_name": "Fgfr1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4U9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7F4U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4U9" } ] } ] }, { "uniprot_ac": "A0A9J7F6S3", "gene_name": "Insrr", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F6S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6S3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7F6S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6S3" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7FB39", "gene_name": "Epha2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FB39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB39" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7FB39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB39" } ] } ] }, { "uniprot_ac": "A0A9J7FEZ2", "gene_name": "Ephb2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7FEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ2" } ] } ] }, { "uniprot_ac": "A0A9J7FIT0", "gene_name": "Pdgfrb", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIT0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7FIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIT0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FT87", "gene_name": "Tyk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FT87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT87" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FT87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT87" } ] } ] }, { "uniprot_ac": "A0A9J7FUX7", "gene_name": "Ephb3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUX7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7FUX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUX7" } ] } ] }, { "uniprot_ac": "A0A9J7FX84", "gene_name": "Mst1r", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX84" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7FX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX84" } ] } ] }, { "uniprot_ac": "A0A9J7FZG2", "gene_name": "Ephb4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7FZG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG2" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G2Q4", "gene_name": "Abl2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G2Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2Q4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7G2Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2Q4" } ] } ] }, { "uniprot_ac": "A0A9J7G398", "gene_name": "Matk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G398", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G398" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7G398", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G398" } ] } ] }, { "uniprot_ac": "A0A9J7G654", "gene_name": "Ltk", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G654", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G654" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7G654", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G654" } ] } ] }, { "uniprot_ac": "A0A9J7G9F9", "gene_name": "Erbb2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7G9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F9" } ] } ] }, { "uniprot_ac": "A0A9J7GBI2", "gene_name": "LOC100771767", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHS8", "gene_name": "Axl", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHS8", "database": "UniProtKB", "url": 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"A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GJW5", "gene_name": "Ret", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJW5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7GJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJW5" } ] } ] }, { "uniprot_ac": "A0A9J7GLP2", "gene_name": "Tek", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GLP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLP2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7GLP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLP2" } ] } ] }, { "uniprot_ac": "A0A9J7GMF3", "gene_name": "LOC103158537", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] } ] }, { "uniprot_ac": "A0A9J7GP54", "gene_name": "Lck", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP54" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GP54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP54" } ] } ] }, { "uniprot_ac": "A0A9J7GRN1", "gene_name": "Ntrk2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRN1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7GRN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRN1" } ] } ] }, { "uniprot_ac": "A0A9J7GSH6", "gene_name": "Lyn", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GSH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GSH6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GSH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GSH6" } ] } ] }, { "uniprot_ac": "A0A9J7GT89", "gene_name": "LOC100774420", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] } ] }, { "uniprot_ac": "A0A9J7GVJ0", "gene_name": "LOC113830699", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GVJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVJ0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7GVJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVJ0" } ] } ] }, { "uniprot_ac": "A0A9J7GVQ2", "gene_name": "Fgfr2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GVQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVQ2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7GVQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVQ2" } ] } ] }, { "uniprot_ac": "A0A9J7GY37", "gene_name": "Src", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GY37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY37" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GY37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY37" } ] } ] }, { "uniprot_ac": "A0A9J7GYA4", "gene_name": "Ephb1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GYA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYA4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7GYA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYA4" } ] } ] }, { "uniprot_ac": "A0A9J7H167", "gene_name": "Epha3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H167", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H167" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7H167", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H167" } ] } ] }, { "uniprot_ac": "A0A9J7H847", "gene_name": "Jak3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H847", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H847" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7H847", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H847" } ] } ] }, { "uniprot_ac": "A0A9J7H923", "gene_name": "Bmx", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H923", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H923" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7H923", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H923" } ] } ] }, { "uniprot_ac": "A0A9J7H9K9", "gene_name": "Erbb3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H9K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9K9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7H9K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9K9" } ] } ] }, { "uniprot_ac": "A0A9J7HE43", "gene_name": "Egfr", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7HE43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE43" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7HE43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE43" } ] } ] }, { "uniprot_ac": "A0A9J7HEE3", "gene_name": "LOC100774072", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7HEE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEE3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7HEE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEE3" } ] } ] }, { "uniprot_ac": "A0A9J7JLX1", "gene_name": "Tyro3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLX1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7JLX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLX1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JTY4", "gene_name": "Fgr", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTY4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JTY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTY4" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K378", "gene_name": "Musk", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K378", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K378" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7K378", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K378" } ] } ] }, { "uniprot_ac": "A0A9J7K3R5", "gene_name": "LOC100760475", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3R5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7K3R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3R5" } ] } ] }, { "uniprot_ac": "A0A9J7K499", "gene_name": "Flt1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K499", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K499" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7K499", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K499" } ] } ] }, { "uniprot_ac": "A0A9J7K5K0", "gene_name": "Ptk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K5K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5K0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7K5K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5K0" } ] } ] }, { "uniprot_ac": "A0A9J7K8D7", "gene_name": "Flt3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8D7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7K8D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8D7" } ] } ] }, { "uniprot_ac": "A0A9J7KAA7", "gene_name": "Flt4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KAA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAA7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7KAA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAA7" } ] } ] }, { "uniprot_ac": "A0A9J7KBU9", "gene_name": "Itk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KBU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBU9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7KBU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBU9" } ] } ] }, { "uniprot_ac": "A0A9J7KFV4", "gene_name": "LOC100767740", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7KFV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV4" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308897" } ] }, { "annotation": "Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits known to mediate synaptic transmission in the nervous system and the neuromuscular junction. Each nAchR subunit confers differential attributes to channel properties, including activation, deactivation and desensitization kinetics, pH sensitivity, cation permeability, and binding to allosteric modulators. Has an accessory rather than functional role and is only able to form functional nAChRs when co-assembled with another beta subunit. Participates in pentameric assemblies along with CHRNA3, CHRNA4, CHRNA6, CHRNB2 and CHRNB4. Modulates receptor assembly and increases receptor sensitivity to nicotine when associated with CHRNB2, CHRNA4 and/or CHRNA6 as well as CHRNA3 and CHRNB4. Seems to play a role in nicotine addiction.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH5#function" }, { "database": "UniProtKB", "id": "ARBA00055594", "url": "https://www.uniprot.org/uniprotkb/ARBA00055594#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Chrnb3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH5", "locus": {} } ], "crossref": [ { "id": "A0A9J7HEH5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HEH5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19064", "url": 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"MSACSETDGPRGSPVTLTATEGLSSIAQHEDALLRHLFQGYQKWVRPVLNSSDTIKVYFGLKISQLVDVEWTDQKLRWNPEEYGGINSIKVPSESLWLPDIVLFENADGRFEGSLMTKAIVRSSGTISWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGSMVDLILINENVDRKDFFDNGEWEILNAKGMKGNRREGFYSYPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLQKLPRWLCMKDPMDRFSFPDGEEKRGAVRGKVSGKKKQTPTSDGEKVLITFLERAAESIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLTVSVLGSILIFIPALKMWLHHSL", "length": 444, "header": "tr|A0A9J7HEH5-1|A0A9J7HEH5_CRIGR Isoform 1 of Neuronal acetylcholine receptor subunit beta-3 OS=Cricetulus griseus OX=10029 GN=Chrnb3 PE=3 SV=1 CANONICAL=A0A9J7HEH5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HEH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH5/entry#A0A9J7HEH5-1", "sequence": { "sequence": "MSACSETDGPRGSPVTLTATEGLSSIAQHEDALLRHLFQGYQKWVRPVLNSSDTIKVYFGLKISQLVDVEWTDQKLRWNPEEYGGINSIKVPSESLWLPDIVLFENADGRFEGSLMTKAIVRSSGTISWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGSMVDLILINENVDRKDFFDNGEWEILNAKGMKGNRREGFYSYPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLQKLPRWLCMKDPMDRFSFPDGEEKRGAVRGKVSGKKKQTPTSDGEKVLITFLERAAESIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLTVSVLGSILIFIPALKMWLHHSL", "length": 444, "header": "tr|A0A9J7HEH5-1|A0A9J7HEH5_CRIGR Isoform 1 of Neuronal acetylcholine receptor subunit beta-3 OS=Cricetulus griseus OX=10029 GN=Chrnb3 PE=3 SV=1 CANONICAL=A0A9J7HEH5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774746", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774746", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH5" } ], "pmid": "" }, { "name": "extracellular ligand-gated monoatomic ion channel activity", "id": "GO:0005230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005230", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "synaptic membrane", "id": "GO:0097060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097060", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEH5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] }, { "id": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HEI4-1", "uniprot_ac": "A0A9J7HEI4", "uniprot_id": "A0A9J7HEI4_CRIGR", "mass": { "chemical_mass": 146687.0, "monoisotopic_mass": 146687.0 }, "refseq": { "ac": "XP_035308912", "name": "protein cordon-bleu", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308912" }, "gene_names": [ { "name": "Cobl", "type": "recommended", "evidence": [ { "id": "A0A9J7HEI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEI4" } ] }, { "name": "Cobl", "type": "synonym", "evidence": [ { "id": "XP_035308912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308912" } ] } ], "protein_names": [ { "name": "Protein cordon-bleu", "type": "synonym", "evidence": [ { "id": "A0A9J7HEI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEI4/entry#names_and_taxonomy" } ] }, { "name": "protein cordon-bleu", "type": "synonym", 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308912" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEI4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEI4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cobl", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEI4", "locus": {} } ], "crossref": [ { "id": "cd21799", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21799", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21800", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21800", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21801", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21801", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761073", "url": "https://www.ncbi.nlm.nih.gov/gene/100761073", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761073", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761073", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HEI4", "url": 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"length": 1353, "header": "tr|A0A9J7HEI4-1|A0A9J7HEI4_CRIGR Isoform 1 of Protein cordon-bleu OS=Cricetulus griseus OX=10029 GN=Cobl PE=4 SV=1 CANONICAL=A0A9J7HEI4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEI4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEI4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEI4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEI4" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEI4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEI4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEI4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEI4" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": 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Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 13% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: incomplete on the amino end.", "evidence": [ { "database": "RefSeq", "id": "XP_035309441", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309441" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEJ0#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEJ0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113839058", "url": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: incomplete on both ends.", "evidence": [ { "database": "RefSeq", "id": "XP_035309338", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309338" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEM3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC118239736", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEM3", "locus": {} } ], "crossref": [ { "id": "118239736", "url": "https://www.ncbi.nlm.nih.gov/gene/118239736", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:118239736", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239736", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_035309338", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309338", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HEM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HEM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "SPSSPPSPSSSSPSSPSLSSSSSSSPPSPSSSSPSSPSLSSPSPSSPPSPSSSSPSSPSLSSSSSSSSPPSPSSSSPSSPSLSSPSPSSSPSPSPSSPSSSSSSSPSPPSSPSSPSPSSSPSSSSSLSSPSSPPSPSSSSPSSSSSSPSSPPSPSSSSPSSPSLSSPSPSSSPSSPSSSSSSXPSSPSSPSSSSPSSPSPSSSPSSPPSPSSSPSSPPSPSSPSPSSPSSSSSSPSSPSSPPSPSSPSPSSSPSSSSSSPSSPSSPPSP", "length": 269, "header": "tr|A0A9J7HEM3-1|A0A9J7HEM3_CRIGR Isoform 1 of LOW QUALITY PROTEIN: vegetative cell wall protein gp1-like OS=Cricetulus griseus OX=10029 GN=LOC118239736 PE=4 SV=1 CANONICAL=A0A9J7HEM3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HEM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEM3/entry#A0A9J7HEM3-1", "sequence": { "sequence": "SPSSPPSPSSSSPSSPSLSSSSSSSPPSPSSSSPSSPSLSSPSPSSPPSPSSSSPSSPSLSSSSSSSSPPSPSSSSPSSPSLSSPSPSSSPSPSPSSPSSSSSSSPSPPSSPSSPSPSSSPSSSSSLSSPSSPPSPSSSSPSSSSSSPSSPPSPSSSSPSSPSLSSPSPSSSPSSPSSSSSSXPSSPSSPSSSSPSSPSPSSSPSSPPSPSSSPSSPPSPSSPSPSSPSSSSSSPSSPSSPPSPSSPSPSSSPSSSSSSPSSPSSPPSP", "length": 269, "header": "tr|A0A9J7HEM3-1|A0A9J7HEM3_CRIGR Isoform 1 of LOW QUALITY PROTEIN: vegetative cell wall protein gp1-like OS=Cricetulus griseus OX=10029 GN=LOC118239736 PE=4 SV=1 CANONICAL=A0A9J7HEM3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEM3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"id": "A0A9J7HEP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEP2" } ] }, { "name": "LOC113837940", "type": "synonym", "evidence": [ { "id": "XP_035309519", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309519" } ] } ], "protein_names": [ { "name": "Ephrin-B2-like", "type": "synonym", "evidence": [ { "id": "A0A9J7HEP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEP2/entry#names_and_taxonomy" } ] }, { "name": "ephrin-B2-like", "type": "synonym", "evidence": [ { "id": "XP_035309519", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309519" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309519", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309519" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEP2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEP2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113837940", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEP2", "locus": {} } ], "crossref": [ { "id": "A0A9J7HEP2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HEP2", "database": "AlphaFoldDB", "categories": [] }, { "id": "113837940", "url": "https://www.ncbi.nlm.nih.gov/gene/113837940", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A9J7HEQ9-1", "uniprot_ac": "A0A9J7HEQ9", "uniprot_id": "A0A9J7HEQ9_CRIGR", "mass": { "chemical_mass": 62260.0, "monoisotopic_mass": 62260.0 }, "refseq": { "ac": "XP_035308306", "name": "LOW QUALITY PROTEIN: casein kinase I-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308306" }, "gene_names": [ { "name": "LOC113838165", "type": "recommended", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ] }, { "name": "LOC113838165", "type": "synonym", "evidence": [ { "id": "XP_035308306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308306" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: casein kinase I-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035308306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308306" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 25% of CDS bases frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308306", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308306" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEQ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113838165", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9", "locus": {} } ], "crossref": [ { "id": "A0A9J7HEQ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HEQ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14126", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14126", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113838165", "url": "https://www.ncbi.nlm.nih.gov/gene/113838165", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113838165", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838165", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HEQ9", "url": "https://www.orthodb.org/?gene=A0A9J7HEQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11909", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11909", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308306", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308306", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HEQ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HEQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDHSNREKDDRQRTTQTMAQRNTHCSRPCGTSASSGGLMVGPNFRVGKKIGCGKFGELRLGKTLYTNEYVAIKVEQIKSRGPPLYLEYRFYEQLGSAGEGIPQVYYFGPCGKYNAMVLELLGPSLQDLFDLCDRTFTLKTVLMIAIQLLSRMEYLHSKNLIYRDVKPENFLIGQQGNKKEHVIHIIDFGLAKEYIDPETKNHIPYGEHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLHGSLPWQELKADTLKERHQKIGDSKRNTPIQVLCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLLERKGYTFDYAYDWVGRPIPTPVGSVHVDSGASVITRESHTHRDLPSQQQPLRNQTASSGRRGEWEIQPSWQTNTSFLASHLAADRHGGSVQVPTVVPVLLSLAPEILQPLEHRNTVRFFHVMDTLKLIYVVMEYVAGKDLATILNGKGYLKEDEGGPIFLQVVSAVHFLHKRHIAYCDIELENILVDRAGDIKLCDFGMAIQLKERKMLKKVCGTLFYMAPEILARKTL", "length": 544, "header": "tr|A0A9J7HEQ9-1|A0A9J7HEQ9_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=LOC113838165 PE=3 SV=1 CANONICAL=A0A9J7HEQ9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HEQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9/entry#A0A9J7HEQ9-1", "sequence": { "sequence": "MDHSNREKDDRQRTTQTMAQRNTHCSRPCGTSASSGGLMVGPNFRVGKKIGCGKFGELRLGKTLYTNEYVAIKVEQIKSRGPPLYLEYRFYEQLGSAGEGIPQVYYFGPCGKYNAMVLELLGPSLQDLFDLCDRTFTLKTVLMIAIQLLSRMEYLHSKNLIYRDVKPENFLIGQQGNKKEHVIHIIDFGLAKEYIDPETKNHIPYGEHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLHGSLPWQELKADTLKERHQKIGDSKRNTPIQVLCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLLERKGYTFDYAYDWVGRPIPTPVGSVHVDSGASVITRESHTHRDLPSQQQPLRNQTASSGRRGEWEIQPSWQTNTSFLASHLAADRHGGSVQVPTVVPVLLSLAPEILQPLEHRNTVRFFHVMDTLKLIYVVMEYVAGKDLATILNGKGYLKEDEGGPIFLQVVSAVHFLHKRHIAYCDIELENILVDRAGDIKLCDFGMAIQLKERKMLKKVCGTLFYMAPEILARKTL", "length": 544, "header": "tr|A0A9J7HEQ9-1|A0A9J7HEQ9_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=LOC113838165 PE=3 SV=1 CANONICAL=A0A9J7HEQ9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEQ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEQ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113838165", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838165", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEQ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEQ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEQ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HEQ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", "A0A8C2QND0-1", "G3HXQ8-1", "G3I724-1", "A0A8C2M0A2-1", "A0A9J7K2S5-1", "A0A8C2MMZ5-1", "A0A8C2QH69-1", "A0A8C2QL63-1", "A0A9J7K953-1", "A0A9J7G3C1-1", "A0A9J7GFS3-1", "A0A9J7JBH0-1", "A0A9J7FGD3-1", "A0A9J7FKM1-1", "A0A9J7JKJ1-1", "A0A9J7G180-1", "A0A9J7JTL3-1", "A0A9J7GQ42-1", "A0A9J7EZ53-1", "A0A9J7J5Z8-1", "A0A9J7EVK4-1", "A0A9J7F0G6-1", "A0A9J7FCC7-1", "A0A9J7K3S4-1", "A0A9J7GAF4-1", "A0A9J7GBF4-1", "A0A8C2MTI7-1", "A0A9J7J1N3-1", "A0A9J7F4P4-1", "A0A9J7JNU2-1", "A0A9J7FZY8-1", "A0A9J7H3M5-1", "A0A9J7JJV6-1", "A0A9J7GJE4-1", "A0A8C2LY52-1", "A0A9J7H8U3-1", "A0A9J7F821-1", "A0A8C2N185-1", "A0A9J7KFV8-1", "A0A8C2MQM0-1", "A0A8C2N310-1", "A0A9J7J6H1-1", "A0A9J7H2P9-1", "A0A9J7H4N5-1", "A0A3L7GPC7-1", "A0A9J7H6V8-1", "A0A3L7HV37-1", "A0A8C2LTZ7-1", "A0A9J7K7D8-1", "A0A8C2LDU9-1", "A0A8C2LTW4-1", "A0A9J7JAM4-1", "A0A9J7JXM2-1", "A0A9J7JRJ8-1", "A0A8C2QEB8-1", "A0A3L7HKC4-1", "A0A8C2LI14-1", "A0A8C2QDX9-1", "A0A9J7G1D9-1", "A0A9J7F985-1", "A0A8C2MCX3-1", "A0A8C2MEU5-1", "A0A8C2MFN1-1", "A0A8C2MMI4-1", "A0A9J7JAB2-1", "A0A9J7G969-1", "A0A8C2MQ42-1", "A0A8C2MR08-1", "A0A8C2MUQ5-1", "A0A9J7FZA7-1", "A0A8C2N3C9-1", "A0A8C2N6L4-1", "A0A8C2N9X1-1", 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"evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3HX91-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", 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"A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] } ] }, { "uniprot_ac": "A0A8C2M497", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] } ] }, { "uniprot_ac": "A0A8C2N185", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] } ] }, { "uniprot_ac": "A0A8C2N210", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] } ] }, { "uniprot_ac": "A0A8C2N3I1", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] } ] }, { "uniprot_ac": "A0A8C2N3U2", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] } ] }, { "uniprot_ac": "A0A8C2N457", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] } ] }, { "uniprot_ac": "A0A8C2N4W2", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] } ] }, { "uniprot_ac": "A0A8C2N6L4", "gene_name": "Prkg1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N6L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L4" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8C2N6L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L4" } ] } ] }, { "uniprot_ac": "A0A8C2N756", "gene_name": "Map2k5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N756" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2N756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N756" } ] } ] }, { "uniprot_ac": "A0A8C2N9X1", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N9X1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2N9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N9X1" } ] } ] }, { "uniprot_ac": "A0A8C2QDX9", "gene_name": "Csnk1g1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] } ] }, { "uniprot_ac": "A0A8C2QEB8", "gene_name": "Bub1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEB8" } ] } ] }, { "uniprot_ac": "A0A8C2QGY5", "gene_name": "Ttbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QGY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGY5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QGY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGY5" } ] } ] }, { "uniprot_ac": "A0A8C2QH69", "gene_name": "Sgk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QH69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QH69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH69" } ] } ] }, { "uniprot_ac": "A0A8C2QHF9", "gene_name": "Lrrk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] } ] }, { "uniprot_ac": "A0A8C2QHS8", "gene_name": "Ripk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] } ] }, { "uniprot_ac": "A0A8C2QI80", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] } ] }, { "uniprot_ac": "A0A8C2QIA1", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] } ] }, { "uniprot_ac": "A0A8C2QJ34", "gene_name": "Oxsr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] } ] }, { "uniprot_ac": "A0A8C2QJA4", "gene_name": "Pak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJA4" } ] } ] }, { "uniprot_ac": "A0A8C2QKP7", "gene_name": "Nlk", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QKP7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QKP7" } ] } ] }, { "uniprot_ac": "A0A8C2QL63", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] } ] }, { "uniprot_ac": "A0A8C2QLT0", "gene_name": "Nek9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] } ] }, { "uniprot_ac": "A0A8C2QMB3", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] } ] }, { "uniprot_ac": "A0A8C2QND0", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] } ] }, { "uniprot_ac": "A0A8C2QNX2", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] } ] }, { "uniprot_ac": "A0A8C2QPB0", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] } ] }, { "uniprot_ac": "A0A9J7EUQ5", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] } ] }, { "uniprot_ac": "A0A9J7EVK4", "gene_name": "Bmp2k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] } ] }, { "uniprot_ac": "A0A9J7EVN3", "gene_name": "LOC100754361", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] } ] }, { "uniprot_ac": "A0A9J7EXX8", "gene_name": "LOC113832238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] } ] }, { "uniprot_ac": "A0A9J7F0J6", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F821", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] } ] }, { "uniprot_ac": "A0A9J7F8T0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] } ] }, { "uniprot_ac": "A0A9J7G5N9", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": 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"ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] } ] }, { "uniprot_ac": "A0A9J7GAF4", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8W9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H8W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8W9" } ] } ] }, { "uniprot_ac": "A0A9J7H949", "gene_name": "LOC100750729", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H949" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H949" } ] } ] }, { "uniprot_ac": "A0A9J7HEQ9", "gene_name": "LOC113838165", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ] } ] }, { "uniprot_ac": "A0A9J7J1N3", "gene_name": "Limk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J1N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J1N3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7J1N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J1N3" } ] } ] }, { "uniprot_ac": "A0A9J7J5Z8", "gene_name": "Camk2g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7J5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5Z8" } ] } ] }, { "uniprot_ac": "A0A9J7J6E9", "gene_name": "Vrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J6E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7J6E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6E9" } ] } ] }, { "uniprot_ac": "A0A9J7J6H1", "gene_name": "LOC100752268", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J6H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6H1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7J6H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6H1" } ] } ] }, { "uniprot_ac": "A0A9J7J728", "gene_name": "LOC113832236", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J728", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J728" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7J728", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J728" } ] } ] }, { "uniprot_ac": "A0A9J7JA07", "gene_name": "LOC100750629", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA07" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA07" } ] } ] }, { "uniprot_ac": "A0A9J7JAB2", "gene_name": "Stk24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAB2" } ] } ] }, { "uniprot_ac": "A0A9J7JAM4", "gene_name": "Sik1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JAM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAM4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JAM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAM4" } ] } ] }, { "uniprot_ac": "A0A9J7JB60", "gene_name": "Dclk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JB60" } ] } ] }, { "uniprot_ac": "A0A9J7JBH0", "gene_name": "Srpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JBH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JBH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH0" } ] } ] }, { "uniprot_ac": "A0A9J7JDU1", "gene_name": "Cdc42bpg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JDU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDU1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JDU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDU1" } ] } ] }, { "uniprot_ac": "A0A9J7JGG9", "gene_name": "Riok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JGG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGG9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JGG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGG9" } ] } ] }, { "uniprot_ac": "A0A9J7JGQ1", "gene_name": "Trpm6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGQ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGQ1" } ] } ] }, { "uniprot_ac": "A0A9J7JGR2", "gene_name": "Rock1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JGR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A9J7JGR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR2" } ] } ] }, { "uniprot_ac": "A0A9J7JHJ2", "gene_name": "Mast2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JQZ1", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] } ] }, { "uniprot_ac": "A0A9J7JRI3", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": 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:: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. 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] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A9J7HF32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF32/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A9J7HF32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF32/entry#names_and_taxonomy" } ] }, { "name": "ras-like protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035309752", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309752" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277199.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309752", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309752" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF32", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF32" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113838146", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF32", "locus": {} } ], "crossref": [ { "id": "cd04138", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04138", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113838146", "url": "https://www.ncbi.nlm.nih.gov/gene/113838146", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309752", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309752", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HF32", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HF32-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEYKLVVVGADGVGKTALTIQLIQYHFVDVYDPTIEDSYRKQVEIDGEICHLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAMNNTKSFEAIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKINGKKKKKKSKTKCIIM", "length": 187, "header": "tr|A0A9J7HF32-1|A0A9J7HF32_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113838146 PE=3 SV=1 CANONICAL=A0A9J7HF32-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HF32-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF32/entry#A0A9J7HF32-1", "sequence": { "sequence": "MTEYKLVVVGADGVGKTALTIQLIQYHFVDVYDPTIEDSYRKQVEIDGEICHLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAMNNTKSFEAIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKINGKKKKKKSKTKCIIM", "length": 187, "header": "tr|A0A9J7HF32-1|A0A9J7HF32_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113838146 PE=3 SV=1 CANONICAL=A0A9J7HF32-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF32", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF32" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF32", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF32" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF32", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF32" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF32", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRJ8-1", "G3GY22-1", "G3H2D6-1", "G3HID1-1", "A0A9J7FY79-1", "G3IBI0-1", "G3HIM4-1", "G3HLW5-1", "G3I0B0-1", "G3H8L7-1", "G3IMU0-1", "G3HQ45-1", "G3HX83-1", "G3H515-1", "G3HRK4-1", "G3HWS3-1", "G3I185-1", "G3I2E9-1", "G3IHJ9-1", "G3I5Q9-1", "G3H3P1-1", "G3HGA7-1", "A0A9J7K0Q7-1", "G3I8B8-1", "A0A9J7FPY4-1", "A0A9J7JNI7-1", "A0A9J7JTM0-1", "G3HXK0-1", "G3I1T6-1", "A0A8C2M8V3-1", "G3HAT4-1", "G3HBU1-1", "A0A8C2MG78-1", "A0A9J7JFJ5-1", "A0A061I5F7-1", "A0A9J7GMX4-1", "G3H3X0-1", "A0A8C2MG41-1", "A0A8C2MJU2-1", "A0A8C2MKJ3-1", "A0A8C2QMP3-1", "A0A9J7F720-1", "A0A061IFE4-1", "A0A061HZZ7-1", "A0A8C2M6H7-1", "A0A8C2M9W6-1", "A0A9J7H2L4-1", "A0A8C2MH13-1", "A0A8C2MMV7-1", "A0A8C2MPE2-1", "A0A8C2LL65-1", "A0A3L7HXE9-1", "A0A8C2LGZ8-1", "A0A8C2LIB5-1", "A0A8C2LNU7-1", "A0A9J7JYH7-1", "A0A8C2LV21-1", "A0A9J7GDV9-1", "A0A8C2QEY0-1", "A0A9J7FVQ6-1", "A0A9J7K0X9-1", "A0A9J7J7P8-1", "A0A8C2M2X0-1", "A0A8C2MAV7-1", "A0A8C2MQL3-1", "A0A3L7HA69-1", "A0A8C2LLE7-1", "A0A061HWM0-1", "A0A061I5K5-1", "A0A061IH58-1", "A0A061INW8-1", "A0A3L7GXQ2-1", "A0A9J7GN19-1", "A0A3L7HQ44-1", "A0A3L7IA35-1", "A0A3L7IMK5-1", "A0A8C2LIE2-1", "A0A9J7GAZ9-1", "A0A9J7HCG9-1", "A0A9J7HC46-1", "A0A9J7HC79-1", "A0A9J7HCE0-1", "A0A9J7JRE1-1", "A0A9J7GJ78-1", "A0A9J7GKH5-1", "A0A9J7GL76-1", "A0A9J7GLC6-1", "A0A9J7GRC9-1", "A0A9J7GM12-1", "A0A9J7GM74-1", "A0A9J7GP64-1", "A0A9J7GPV5-1", "A0A9J7GQI1-1", "A0A9J7GR82-1", "A0A9J7JY44-1", "A0A9J7JTP9-1", "A0A9J7HGR2-1", "A0A9J7JZZ6-1", "A0A9J7K3I9-1", "A0A9J7K4X6-1", "A0A9J7HD72-1", "A0A9J7KEX2-1", "A0A9J7KFX8-1", "A0A9J7KEY0-1", "A0A9J7KF02-1", "A0A9J7KF14-1", "A0A9J7HFH8-1", "A0A9J7HEY0-1", "A0A9J7KG38-1", "A0A9J7HCJ6-1", "A0A9J7HCM3-1", "A0A9J7HCS9-1", "A0A9J7HD53-1", "A0A9J7HD81-1", "A0A9J7HFN4-1", "A0A9J7HCM7-1", "A0A9J7HCP3-1", "A0A9J7HD44-1", "A0A9J7HFL5-1", "A0A9J7HEX1-1", 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. 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"https://www.ncbi.nlm.nih.gov/protein/XP_035309188", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HF48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HF48-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFM4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFM4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWVEVTMLKRETKADSDRPRKVRFRIASSHSGRVLKEVYEDGQPPASLDSECASVCGIGGLRDSEGQQNGHIGSEDNEHEKDQDNLLVLARTASEKAFGTRRVNILSKNGTVRGVKYKVSAGQALFNNLTKVLQQPLADLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGDYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDLLTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSVFRNCFTDAFKALKCTACNENGLQRCKNCAG", "length": 296, "header": "tr|A0A9J7HF48-1|A0A9J7HF48_CRIGR Isoform 1 of Glutaredoxin domain-containing cysteine-rich protein 1 OS=Cricetulus griseus OX=10029 GN=LOC100764131 PE=3 SV=1 CANONICAL=A0A9J7HF48-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HF48-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF48/entry#A0A9J7HF48-1", "sequence": { "sequence": "MWVEVTMLKRETKADSDRPRKVRFRIASSHSGRVLKEVYEDGQPPASLDSECASVCGIGGLRDSEGQQNGHIGSEDNEHEKDQDNLLVLARTASEKAFGTRRVNILSKNGTVRGVKYKVSAGQALFNNLTKVLQQPLADLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGDYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDLLTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSVFRNCFTDAFKALKCTACNENGLQRCKNCAG", "length": 296, "header": "tr|A0A9J7HF48-1|A0A9J7HF48_CRIGR Isoform 1 of Glutaredoxin domain-containing cysteine-rich protein 1 OS=Cricetulus griseus OX=10029 GN=LOC100764131 PE=3 SV=1 CANONICAL=A0A9J7HF48-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KFM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF48/entry#A0A9J7KFM4-1", "sequence": { "sequence": "MWVEVTMLKRETKADSDRPRKVRFRIASSHSGRVLKEVYEDGQPPASLDSECASVCGIGGLRDSEGQQNGHIGSEDNEHEKDQDNLLVLARTASEKAFGTRRVNILSKNGTVRGVKYKVSAGQALFNNLTKVLQPAHPESQARISKDLVPPKNASQSSKRPPSHQMRRHQHKDTWVMKNQRNTAPSKDTKNALEMDEDEKEIYEMTDKEFRIILLKKFRELQDNTDRKLSEIQEIINKQHEMFDREIKVNHFKIKILEIKNTISELANSTTGFNRRLDRAEGRINELEDWTYDSRL", "length": 296, "header": "tr|A0A9J7KFM4-1|A0A9J7HF48_CRIGR Computationally mapped isoform of Glutaredoxin domain-containing cysteine-rich protein 1 OS=Cricetulus griseus OX=10029 GN=LOC100764131 PE=3 SV=1 CANONICAL=A0A9J7HF48-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFM4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFM4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFM4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFM4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764131", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764131", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF48" } ], "pmid": "" }, { "name": "inner ear receptor cell stereocilium organization", "id": "GO:0060122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060122", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF48" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF48" } ], "pmid": "" }, { "name": "kinocilium", "id": "GO:0060091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060091", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF48" } ], "pmid": "" }, { "name": "stereocilium", "id": "GO:0032420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032420", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HF48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF48" }, { "id": "PF00462", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00462" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glutaredoxin", "eco_id": "ECO_0000259", "start_pos": 145, "end_pos": 213, "start_aa": "Val", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 128, "end_pos": 130 }, { "start_pos": 224, "end_pos": 226 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A9J7HF57-1", "uniprot_ac": "A0A9J7HF57", "uniprot_id": "A0A9J7HF57_CRIGR", "mass": { "chemical_mass": 73415.0, "monoisotopic_mass": 73415.0 }, "refseq": { "ac": "XP_035309649", "name": "LOW QUALITY PROTEIN: forkhead box protein P4-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309649" }, "gene_names": [ { "name": "LOC113838907", "type": "recommended", "evidence": [ { "id": "A0A9J7HF57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF57" } ] }, { "name": "LOC113838907", "type": "synonym", "evidence": [ { "id": "XP_035309649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309649" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: forkhead box protein P4-like", "type": "synonym", "evidence": [ { "id": "XP_035309649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309649" }, { "id": "A0A9J7HF57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF57/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel internal stop codons :: corrected 2 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276919.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309649", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309649" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HF57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF57" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113838907", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF57", "locus": {} } ], "crossref": [ { "id": "113838907", "url": "https://www.ncbi.nlm.nih.gov/gene/113838907", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032354", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032354", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113838907", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838907", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HF57", "url": "https://www.orthodb.org/?gene=A0A9J7HF57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45796", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45796", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45796:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45796:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309649", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309649", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HF57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HF57-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMEESAWETIRSAPNGQKGGVGSLPGQADGGSGSGMAGMAAVAGRDGSGRDTTRGADSVGKMSSMELLQFQQQQAFQVSRQFLLQQASNLNSPGNKDSIQLASALQVPMSEAMMSQHMLTPQQMQQNLSXPQLQALLQQQQALMPQQLQEYYKQQQQQLHLQILTQQQAGKQQPRESLGSTQLAFQQQLLQMQQLQQQHLLNLQRQGLVHLQPSQASWPLQALPQAAACPTDLPELWKGKGAPGQPAEDSIRQEGLDLASTAATATWFASAPKVSPPLSHHPLPNRQPTVLTPRRDSSSHEETPSSHPLYGHGECNWPGGETLCEDLGQFIKHLNTEHALDDQSTAQCQEQMQVVQQLEIQLTKESERFQAMKAHVHMGPSEPKPFCQPVTVSSDPFPDGLVHAPTSAAAPVTPLQPRGLGSTSLHSGGPARRRSSHEFGSPIYSELPKYHDYFKNVAVRPPFTYASLIRQAILESPDRQLTLKEICNWITRMFAFFXGKTDNWKKVVSQNLRMHECFVKVETVKGAVWTVEEQKYQKRRSSRMTGSDDLGPQFWPLNTSYQAALAESNFPFLNSPDKLNPGSASSLLPLSQDDMGAPGEPLPCKGSSSPPRLSPPQXSHEVQVKEEPAEAEEDRQPWPLLGAPNPSTVGPREDRDLEEDLPGEDMS", "length": 667, "header": "tr|A0A9J7HF57-1|A0A9J7HF57_CRIGR Isoform 1 of LOW QUALITY PROTEIN: forkhead box protein P4-like OS=Cricetulus griseus OX=10029 GN=LOC113838907 PE=4 SV=1 CANONICAL=A0A9J7HF57-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HF57-1", "url": 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027243923", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243923" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J4I1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4I1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zpbp", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J4I1", "locus": {} } ], "crossref": [ { "id": "A0A9J7J4I1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7J4I1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100753352", "url": "https://www.ncbi.nlm.nih.gov/gene/100753352", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010857", 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"MADRKSVVLSRNTVCCPPLGNRKSIVLASRSQPEVSCAVPHAGRWRHTARAAPSPRAAFCRPEAEARHRAGPSLGRQLRGCGRCVLSLIQAAVEPTGQRKWRGHGRDLRFLPGQGLVLYPQIGDKLDIICPKVDSKTVGQYEYYKLYMVDKDQADRCIIKKKKKALLNCSRPHRDVKFTIKFQEFSPKIRGLEFQKNKDYYIISTSNGSLEGLHNQEGGVCQTRSMKXLMKVGQDASPAGSTTNNDPTRHLELEAGTNRRNSITSPFVKPNPGIAMWLGCVSMRCIFLRTPRGREASKHIPTNGIHSWAQVPGVFAPSISTEGNSTGHSRNNLGSKVALFAGIISGCVIFIVIIITLVVLLLKYRRRHGKHSPQHXSKRGGNNSGWEPSDVLIPLRTADNVFCPHYEKVRGDYGDPVYIVQEMPPQNPANIYCKV", "length": 435, "header": "tr|A0A9J7HFE9-1|A0A9J7HFE9_CRIGR Isoform 1 of LOW QUALITY PROTEIN: ephrin-B2 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC103162695 PE=3 SV=1 CANONICAL=A0A9J7HFE9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HFE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFE9/entry#A0A9J7HFE9-1", "sequence": { "sequence": "MADRKSVVLSRNTVCCPPLGNRKSIVLASRSQPEVSCAVPHAGRWRHTARAAPSPRAAFCRPEAEARHRAGPSLGRQLRGCGRCVLSLIQAAVEPTGQRKWRGHGRDLRFLPGQGLVLYPQIGDKLDIICPKVDSKTVGQYEYYKLYMVDKDQADRCIIKKKKKALLNCSRPHRDVKFTIKFQEFSPKIRGLEFQKNKDYYIISTSNGSLEGLHNQEGGVCQTRSMKXLMKVGQDASPAGSTTNNDPTRHLELEAGTNRRNSITSPFVKPNPGIAMWLGCVSMRCIFLRTPRGREASKHIPTNGIHSWAQVPGVFAPSISTEGNSTGHSRNNLGSKVALFAGIISGCVIFIVIIITLVVLLLKYRRRHGKHSPQHXSKRGGNNSGWEPSDVLIPLRTADNVFCPHYEKVRGDYGDPVYIVQEMPPQNPANIYCKV", "length": 435, "header": "tr|A0A9J7HFE9-1|A0A9J7HFE9_CRIGR Isoform 1 of LOW QUALITY PROTEIN: ephrin-B2 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC103162695 PE=3 SV=1 CANONICAL=A0A9J7HFE9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:103162695", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103162695", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, 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"evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFE9" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HFE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFE9" }, { "id": "PS51551", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51551" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ephrin RBD", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 232, "start_aa": "Thr", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 }, { "start_pos": 207, "end_pos": 209 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 382, "end_pos": 384 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A9J7HFF3-1", "uniprot_ac": "A0A9J7HFF3", "uniprot_id": "A0A9J7HFF3_CRIGR", "mass": { "chemical_mass": 67497.0, "monoisotopic_mass": 67497.0 }, "refseq": { "ac": "XP_035309819", "name": "LOW QUALITY PROTEIN: uncharacterized protein LOC113838677", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309819" }, "gene_names": [ { "name": "LOC113838677", "type": "recommended", "evidence": [ { "id": "A0A9J7HFF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFF3" } ] }, { "name": "LOC113838677", "type": "synonym", "evidence": [ { "id": "XP_035309819", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309819" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: uncharacterized protein LOC113838677", "type": "synonym", "evidence": [ { "id": "XP_035309819", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309819" }, { "id": "A0A9J7HFF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFF3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 43% of CDS bases frameshifts :: corrected 3 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277424.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309819", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309819" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFF3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFF3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113838677", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFF3", "locus": {} } ], "crossref": [ { "id": "113838677", "url": "https://www.ncbi.nlm.nih.gov/gene/113838677", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113838677", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838677", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HFF3", "url": "https://www.orthodb.org/?gene=A0A9J7HFF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11304", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11304", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11304:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11304:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00812", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00812", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309819", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309819", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HFF3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HFF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRGGSGTAVSDPGASPPDGFGNAPEAGSRSFHTRDSRRCLRSLCGTRRPVAVALLVRYLRADRKSIVLASKAKGKLGIPGLTSRVPVKSGRSSCGVGKKKDSDRKSVVLASESNRKSGVLDSQAESQSLEAGRSLCAVGTERPGHEVASAGRRSHPEVGHPVRRSRIPVTGSRSFVGAEPLVHLTGTGLRWRPEAKRKSGVLRFQRNSGRWKPAARRSHPLPGLRKSLVLASRSQPEVGNRESQKPHSRLCRGSQNGTGTRPEVCSAGELKPTGDRACETPVTKQCVLPTPRKPEVDSPGELKPTGSLVCCASLGALASHSEGGTESQGGVLQTGSGSASQSGSVPWAAASGMRAMRSELDPGGGGARGPAEVAGPWAGPAVIAVCGFLPGQGLVLYPQIGDKLDIICPKVDSKTVGQYEYYKVYMVDKDQADRCIIKKKKKTLLNCSRPHRDVKFXIKFQEFSPKIRGLEFQKKKDYYIISTSNGSLEGLHNQEGGVCQTRSMKXLMKVGQGISTEGNSAGHSRNNLGSKVALLAGIISGCVIFVIIIITLVVLLLKYRRRHGKHSPQHXSKRGGNNSGWEPSDVLIPLRTADNVFCPHYQKVSGDYGDPVYIVQEMPPQNPANIYCKV", "length": 631, "header": "tr|A0A9J7HFF3-1|A0A9J7HFF3_CRIGR Isoform 1 of LOW QUALITY PROTEIN: uncharacterized protein LOC113838677 OS=Cricetulus griseus OX=10029 GN=LOC113838677 PE=3 SV=1 CANONICAL=A0A9J7HFF3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HFF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFF3/entry#A0A9J7HFF3-1", "sequence": { "sequence": "MSRGGSGTAVSDPGASPPDGFGNAPEAGSRSFHTRDSRRCLRSLCGTRRPVAVALLVRYLRADRKSIVLASKAKGKLGIPGLTSRVPVKSGRSSCGVGKKKDSDRKSVVLASESNRKSGVLDSQAESQSLEAGRSLCAVGTERPGHEVASAGRRSHPEVGHPVRRSRIPVTGSRSFVGAEPLVHLTGTGLRWRPEAKRKSGVLRFQRNSGRWKPAARRSHPLPGLRKSLVLASRSQPEVGNRESQKPHSRLCRGSQNGTGTRPEVCSAGELKPTGDRACETPVTKQCVLPTPRKPEVDSPGELKPTGSLVCCASLGALASHSEGGTESQGGVLQTGSGSASQSGSVPWAAASGMRAMRSELDPGGGGARGPAEVAGPWAGPAVIAVCGFLPGQGLVLYPQIGDKLDIICPKVDSKTVGQYEYYKVYMVDKDQADRCIIKKKKKTLLNCSRPHRDVKFXIKFQEFSPKIRGLEFQKKKDYYIISTSNGSLEGLHNQEGGVCQTRSMKXLMKVGQGISTEGNSAGHSRNNLGSKVALLAGIISGCVIFVIIIITLVVLLLKYRRRHGKHSPQHXSKRGGNNSGWEPSDVLIPLRTADNVFCPHYQKVSGDYGDPVYIVQEMPPQNPANIYCKV", "length": 631, "header": "tr|A0A9J7HFF3-1|A0A9J7HFF3_CRIGR Isoform 1 of LOW QUALITY PROTEIN: uncharacterized protein LOC113838677 OS=Cricetulus griseus OX=10029 GN=LOC113838677 PE=3 SV=1 CANONICAL=A0A9J7HFF3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:113838677", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838677", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFF3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFF3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ephrin receptor binding", "id": "GO:0046875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046875", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFF3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFF3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "ephrin receptor signaling pathway", "id": "GO:0048013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048013", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFF3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFF3" } ], "pmid": "" }, { "name": "blood vessel morphogenesis", "id": "GO:0048514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048514", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFF3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFF3" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFF3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 486, "end_pos": 488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309494", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309494" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFH8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFH8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113838679", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFH8", "locus": {} } ], "crossref": [ { "id": "A0A9J7HFH8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HFH8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04138", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04138", "database": "CDD", "categories": [ "Protein 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##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 43% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309434", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309434" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113839102", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ5", "locus": {} } ], "crossref": [ { "id": "A0A9J7HFJ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HFJ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "113839102", "url": "https://www.ncbi.nlm.nih.gov/gene/113839102", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13703:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13703:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03166", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03166", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309434", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309434", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HFJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HFJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHAAARASHTPPPLPRSARASRLPAVLRGGRIELDFLVPDTPGVSIVPNKRTAAAAERAHSGAEAGPRGGGAEQRAGAGAERPEAGRAESRGGAERPEAGLTRVHLYYVVGEVYVECLSDSSIFVQSWNCNYHHGFHPTTVCKIPSGCSVKIFNNQEFAQILAQSVKHGFETVYELTKMCTIRMSFVKGWGAKYHRQDVTSTPCLIEIYLHGPLQWLDKVLTQMGSPHNPISSVS", "length": 235, "header": "tr|A0A9J7HFJ5-1|A0A9J7HFJ5_CRIGR Isoform 1 of Mothers against decapentaplegic homolog 1-like OS=Cricetulus griseus OX=10029 GN=LOC113839102 PE=4 SV=1 CANONICAL=A0A9J7HFJ5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HFJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ5/entry#A0A9J7HFJ5-1", "sequence": { "sequence": "MHAAARASHTPPPLPRSARASRLPAVLRGGRIELDFLVPDTPGVSIVPNKRTAAAAERAHSGAEAGPRGGGAEQRAGAGAERPEAGRAESRGGAERPEAGLTRVHLYYVVGEVYVECLSDSSIFVQSWNCNYHHGFHPTTVCKIPSGCSVKIFNNQEFAQILAQSVKHGFETVYELTKMCTIRMSFVKGWGAKYHRQDVTSTPCLIEIYLHGPLQWLDKVLTQMGSPHNPISSVS", "length": 235, "header": "tr|A0A9J7HFJ5-1|A0A9J7HFJ5_CRIGR Isoform 1 of Mothers against decapentaplegic homolog 1-like OS=Cricetulus griseus OX=10029 GN=LOC113839102 PE=4 SV=1 CANONICAL=A0A9J7HFJ5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:113839102", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113839102", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "heteromeric SMAD protein complex", "id": "GO:0071144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071144", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ5" } ], "pmid": "" }, { "name": "cell 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"pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ5" } ], "pmid": "" }, { "name": "I-SMAD binding", "id": "GO:0070411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070411", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HFJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ5" }, { "id": "PS51076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MH2", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 235, "start_aa": "Gly", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A9J7HFJ9-1", "uniprot_ac": "A0A9J7HFJ9", "uniprot_id": "A0A9J7HFJ9_CRIGR", "mass": { "chemical_mass": 57342.0, "monoisotopic_mass": 57342.0 }, "refseq": { "ac": "XP_035309526", "name": "polypyrimidine tract-binding protein 1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309526" }, "gene_names": [ { "name": "LOC113838366", "type": "recommended", "evidence": [ { "id": "A0A9J7HFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ9" } ] }, { "name": "LOC113838366", "type": "synonym", "evidence": [ { "id": "XP_035309526", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309526" } ] } ], "protein_names": [ { "name": "Polypyrimidine tract-binding protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7HFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ9/entry#names_and_taxonomy" } ] }, { "name": "Heterogeneous nuclear ribonucleoprotein I", "type": "synonym", "evidence": [ { "id": "A0A9J7HFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ9/entry#names_and_taxonomy" } ] }, { "name": "polypyrimidine tract-binding protein 1-like", "type": "synonym", "evidence": [ { "id": "XP_035309526", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309526" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309526", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309526" } ] }, { "annotation": "Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. Binds to polypyrimidine-rich controlling element (PCE) of CFTR and promotes exon skipping of CFTR exon 9, thereby antagonizing TIA1 and its role in exon inclusion of CFTR exon 9. Plays a role in the splicing of pyruvate kinase PKM by binding repressively to a polypyrimidine tract flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ9#function" }, { "database": "UniProtKB", "id": "ARBA00055436", "url": "https://www.uniprot.org/uniprotkb/ARBA00055436#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113838366", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ9", "locus": {} } ], "crossref": [ { "id": "A0A9J7HFJ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HFJ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12777", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12777", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113838366", "url": "https://www.ncbi.nlm.nih.gov/gene/113838366", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113838366", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838366", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HFJ9", "url": "https://www.orthodb.org/?gene=A0A9J7HFJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309526", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309526", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HFJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HFJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGIVPDIAVGTKRGSDELFSTCVSNGPFIISSSTSAANGNDSKKFKGDNRSTGVPSRVIHVRSLPSDVTEDEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNHARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRILVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNRFQALLQYADPVSAQHAKLSLDGQNIYKAWCSLRIDFSKLTSLYVKYNNDKSRDYTRPDLPSGDSQLSLDQTMAAAFGLSVPNVHRALAPLAIPSAALAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVLRVKILFNNKENALVQMADGSQAQRAMSHLNGHKLHGKSLRIILSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSPTLHLSNIPRSVSEDDLKNLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGDNHHLLVSFSKSTI", "length": 529, "header": "tr|A0A9J7HFJ9-1|A0A9J7HFJ9_CRIGR Isoform 1 of Polypyrimidine tract-binding protein 1 OS=Cricetulus griseus OX=10029 GN=LOC113838366 PE=4 SV=1 CANONICAL=A0A9J7HFJ9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HFJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ9/entry#A0A9J7HFJ9-1", "sequence": { "sequence": "MDGIVPDIAVGTKRGSDELFSTCVSNGPFIISSSTSAANGNDSKKFKGDNRSTGVPSRVIHVRSLPSDVTEDEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNHARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRILVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNRFQALLQYADPVSAQHAKLSLDGQNIYKAWCSLRIDFSKLTSLYVKYNNDKSRDYTRPDLPSGDSQLSLDQTMAAAFGLSVPNVHRALAPLAIPSAALAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVLRVKILFNNKENALVQMADGSQAQRAMSHLNGHKLHGKSLRIILSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSPTLHLSNIPRSVSEDDLKNLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGDNHHLLVSFSKSTI", "length": 529, "header": "tr|A0A9J7HFJ9-1|A0A9J7HFJ9_CRIGR Isoform 1 of Polypyrimidine tract-binding protein 1 OS=Cricetulus griseus OX=10029 GN=LOC113838366 PE=4 SV=1 CANONICAL=A0A9J7HFJ9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:113838366", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838366", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ9" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ9" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ9" } ], "pmid": "" }, { "name": "negative regulation of mRNA metabolic process", "id": "GO:1903312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903312", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFJ9" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 142, "start_aa": "Arg", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 }, { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A9J7HFM5-1", "uniprot_ac": "A0A9J7HFM5", "uniprot_id": "A0A9J7HFM5_CRIGR", "mass": { "chemical_mass": 57125.0, "monoisotopic_mass": 57125.0 }, "refseq": { "ac": "XP_035309481", "name": "LOW QUALITY PROTEIN: polypyrimidine tract-binding protein 1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309481" }, "gene_names": [ { "name": "LOC113838461", "type": "recommended", "evidence": [ { "id": "A0A9J7HFM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM5" } ] }, { "name": "LOC113838461", "type": "synonym", "evidence": [ { "id": "XP_035309481", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309481" } ] } ], "protein_names": [ { "name": "Polypyrimidine tract-binding protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7HFM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM5/entry#names_and_taxonomy" } ] }, { "name": "Heterogeneous nuclear ribonucleoprotein I", "type": "synonym", "evidence": [ { "id": "A0A9J7HFM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM5/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: polypyrimidine tract-binding protein 1-like", "type": "synonym", "evidence": [ { "id": "XP_035309481", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309481" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309481", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309481" } ] }, { "annotation": "Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. Binds to polypyrimidine-rich controlling element (PCE) of CFTR and promotes exon skipping of CFTR exon 9, thereby antagonizing TIA1 and its role in exon inclusion of CFTR exon 9. Plays a role in the splicing of pyruvate kinase PKM by binding repressively to a polypyrimidine tract flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM5#function" }, { "database": "UniProtKB", "id": "ARBA00055436", "url": "https://www.uniprot.org/uniprotkb/ARBA00055436#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113838461", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM5", "locus": {} } ], "crossref": [ { "id": "113838461", "url": "https://www.ncbi.nlm.nih.gov/gene/113838461", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113838461", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838461", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HFM5", "url": "https://www.orthodb.org/?gene=A0A9J7HFM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309481", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309481", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HFM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HFM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGIVPDIAVGTKRGSDELFSMCVSSGPFIMSSSTSAANGNNSKKFKGDNRSTGVPSRVIHVRSLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLCGQPIYLQFSNHKELKTDSSPNHARAQAALQAVNSVQSGNLALAASAAALDAGMAMAGQSPVLRILVENLFYPVTLDVLHQIFFKFGTVLKIITFTKNNRFQALLQYADPVSAQHAKLSLDGQNIYKAWCSLRIDFSKLTSLYVKYNNDKSRDYTRPDLPSGDSQPSLDQTVAAAFGLSVPNVHGALAPLAIPSAASAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVLRVKILFNNKENALVQMVDGSQAQLAMSHLNGHKLHGKSLRIILSKHQSVQLPREGQEDQGVTKDYGSXPLHCFKKPGSKNFQNIFPPSPTLHLSNIPPSVSEDDLKNLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAMQALIELHNHDLGENHHLRVSFSKSTI", "length": 529, "header": "tr|A0A9J7HFM5-1|A0A9J7HFM5_CRIGR Isoform 1 of Polypyrimidine tract-binding protein 1 OS=Cricetulus griseus OX=10029 GN=LOC113838461 PE=4 SV=1 CANONICAL=A0A9J7HFM5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HFM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM5/entry#A0A9J7HFM5-1", "sequence": { "sequence": "MDGIVPDIAVGTKRGSDELFSMCVSSGPFIMSSSTSAANGNNSKKFKGDNRSTGVPSRVIHVRSLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLCGQPIYLQFSNHKELKTDSSPNHARAQAALQAVNSVQSGNLALAASAAALDAGMAMAGQSPVLRILVENLFYPVTLDVLHQIFFKFGTVLKIITFTKNNRFQALLQYADPVSAQHAKLSLDGQNIYKAWCSLRIDFSKLTSLYVKYNNDKSRDYTRPDLPSGDSQPSLDQTVAAAFGLSVPNVHGALAPLAIPSAASAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVLRVKILFNNKENALVQMVDGSQAQLAMSHLNGHKLHGKSLRIILSKHQSVQLPREGQEDQGVTKDYGSXPLHCFKKPGSKNFQNIFPPSPTLHLSNIPPSVSEDDLKNLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAMQALIELHNHDLGENHHLRVSFSKSTI", "length": 529, "header": "tr|A0A9J7HFM5-1|A0A9J7HFM5_CRIGR Isoform 1 of Polypyrimidine tract-binding protein 1 OS=Cricetulus griseus OX=10029 GN=LOC113838461 PE=4 SV=1 CANONICAL=A0A9J7HFM5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:113838461", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838461", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": 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}, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7HFM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM5" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 142, "start_aa": "Arg", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 }, { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM7/entry#names_and_taxonomy" } ] }, { "name": "EPH-related receptor tyrosine kinase ligand 5", "type": "synonym", "evidence": [ { "id": "A0A9J7HFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM7/entry#names_and_taxonomy" } ] }, { "name": "HTK ligand", "type": "synonym", "evidence": [ { "id": "A0A9J7HFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM7/entry#names_and_taxonomy" } ] }, { "name": "ephrin-B2-like", "type": "synonym", "evidence": [ { "id": "XP_035309577", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309577" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276822.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309577", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309577" } ] }, { "annotation": "Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFM7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM7#function" }, { "database": "UniProtKB", "id": "ARBA00057158", "url": "https://www.uniprot.org/uniprotkb/ARBA00057158#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFM7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113839100", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFM7", "locus": {} } ], "crossref": [ { "id": "A0A9J7HFM7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HFM7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10426", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10426", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113839100", "url": "https://www.ncbi.nlm.nih.gov/gene/113839100", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113839100", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113839100", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HFM7", "url": "https://www.orthodb.org/?gene=A0A9J7HFM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11304", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11304", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11304:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11304:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00812", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00812", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309577", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309577", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HFM7", "url": 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"MSVSQSRRDSVWKSGWVLLMVFCRSAISSPTVLEPIYWNSSNARFLPGQGMVLYPQIGDKLDIVCPKVDSKTVGQYEYYKFYKVDKDQADRYTIKKKNTPLLNCSRPHQDVKFSIKFQEFSPNIWGLEFQENKDYYIISTSNGSLEGLHNQEGGVCKTRAMKIIMKVGQGTSTEGNSAGHSANNLLGSKVALFAGITSECIIIIVIIITLVVLLLKYCRRHRKHSPQHTATAKRGGNNSGWEPSDVLIPLKIADSVSRPHYEKVSGDYGHPVCRRCPQSPANINYKV", "length": 287, "header": "tr|A0A9J7HFM7-1|A0A9J7HFM7_CRIGR Isoform 1 of Ephrin-B2 OS=Cricetulus griseus OX=10029 GN=LOC113839100 PE=3 SV=1 CANONICAL=A0A9J7HFM7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:113839100", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113839100", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFM7", "url": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309529", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309529" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFQ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFQ3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC118239770", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFQ3", "locus": {} } ], "crossref": [ { "id": "A0A9J7HFQ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7HFQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04138", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04138", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "118239770", "url": "https://www.ncbi.nlm.nih.gov/gene/118239770", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:118239770", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239770", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HFQ3", "url": "https://www.orthodb.org/?gene=A0A9J7HFQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309529", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309529", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HFQ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HFQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEYKLVVVGADGVGKSALTIQLIQNLFVDVYDPTIEDSYRKQVVIDREICHLDILDTAGLEEYSAMSDQYMRTGEGFLCVFAMNNTKSFEDIHHYREQIKRVKDAEDVPMVLVGNKCDLPSRAVDTKQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKFSKEEKTPGRVKIKKCIVM", "length": 189, "header": "tr|A0A9J7HFQ3-1|A0A9J7HFQ3_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC118239770 PE=3 SV=1 CANONICAL=A0A9J7HFQ3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HFQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFQ3/entry#A0A9J7HFQ3-1", "sequence": { "sequence": "MTEYKLVVVGADGVGKSALTIQLIQNLFVDVYDPTIEDSYRKQVVIDREICHLDILDTAGLEEYSAMSDQYMRTGEGFLCVFAMNNTKSFEDIHHYREQIKRVKDAEDVPMVLVGNKCDLPSRAVDTKQAQDLAGSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKFSKEEKTPGRVKIKKCIVM", "length": 189, "header": "tr|A0A9J7HFQ3-1|A0A9J7HFQ3_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC118239770 PE=3 SV=1 CANONICAL=A0A9J7HFQ3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "cge:118239770", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239770", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFQ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFQ3" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFQ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFQ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFQ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFQ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFQ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRJ8-1", "G3GY22-1", "G3H2D6-1", "G3HID1-1", "A0A9J7FY79-1", "G3IBI0-1", "G3HIM4-1", "G3HLW5-1", "G3I0B0-1", "G3H8L7-1", "G3IMU0-1", "G3HQ45-1", "G3HX83-1", "G3H515-1", "G3HRK4-1", "G3HWS3-1", "G3I185-1", "G3I2E9-1", "G3IHJ9-1", "G3I5Q9-1", "G3H3P1-1", "G3HGA7-1", "A0A9J7K0Q7-1", "G3I8B8-1", "A0A9J7FPY4-1", "A0A9J7JNI7-1", "A0A9J7JTM0-1", "G3HXK0-1", "G3I1T6-1", "A0A8C2M8V3-1", "G3HAT4-1", "G3HBU1-1", "A0A8C2MG78-1", "A0A9J7JFJ5-1", "A0A061I5F7-1", "A0A9J7GMX4-1", "G3H3X0-1", "A0A8C2MG41-1", "A0A8C2MJU2-1", "A0A8C2MKJ3-1", "A0A8C2QMP3-1", "A0A9J7F720-1", "A0A061IFE4-1", "A0A061HZZ7-1", "A0A8C2M6H7-1", "A0A8C2M9W6-1", "A0A9J7H2L4-1", "A0A8C2MH13-1", "A0A8C2MMV7-1", "A0A8C2MPE2-1", "A0A8C2LL65-1", "A0A3L7HXE9-1", "A0A8C2LGZ8-1", "A0A8C2LIB5-1", "A0A8C2LNU7-1", "A0A9J7JYH7-1", "A0A8C2LV21-1", "A0A9J7GDV9-1", "A0A8C2QEY0-1", "A0A9J7FVQ6-1", "A0A9J7K0X9-1", "A0A9J7J7P8-1", "A0A8C2M2X0-1", "A0A8C2MAV7-1", "A0A8C2MQL3-1", "A0A3L7HA69-1", "A0A8C2LLE7-1", "A0A061HWM0-1", "A0A061I5K5-1", "A0A061IH58-1", "A0A061INW8-1", "A0A3L7GXQ2-1", "A0A9J7GN19-1", "A0A3L7HQ44-1", "A0A3L7IA35-1", "A0A3L7IMK5-1", "A0A8C2LIE2-1", "A0A9J7GAZ9-1", "A0A9J7HCG9-1", "A0A9J7HC46-1", "A0A9J7HC79-1", "A0A9J7HCE0-1", "A0A9J7JRE1-1", "A0A9J7GJ78-1", "A0A9J7GKH5-1", "A0A9J7GL76-1", "A0A9J7GLC6-1", "A0A9J7GRC9-1", "A0A9J7GM12-1", "A0A9J7GM74-1", "A0A9J7GP64-1", "A0A9J7GPV5-1", "A0A9J7GQI1-1", "A0A9J7GR82-1", "A0A9J7JY44-1", "A0A9J7JTP9-1", "A0A9J7HGR2-1", "A0A9J7JZZ6-1", "A0A9J7K3I9-1", "A0A9J7K4X6-1", "A0A9J7HD72-1", "A0A9J7KEX2-1", "A0A9J7KFX8-1", "A0A9J7KEY0-1", "A0A9J7KF02-1", "A0A9J7KF14-1", "A0A9J7HFH8-1", "A0A9J7HEY0-1", "A0A9J7KG38-1", "A0A9J7HCJ6-1", "A0A9J7HCM3-1", "A0A9J7HCS9-1", "A0A9J7HD53-1", "A0A9J7HD81-1", "A0A9J7HFN4-1", "A0A9J7HCM7-1", "A0A9J7HCP3-1", "A0A9J7HD44-1", "A0A9J7HFL5-1", "A0A9J7HEX1-1", "A0A9J7HF32-1", "A0A9J7HFQ3-1", "A0A9J7GPD5-1", "A0A9J7HGT1-1", "A0A9J7HH79-1", "A0A9J7GR00-1", "P09445-1", "P62629-1", "P68361-1", "P68362-1", "P68365-1", "Q9QVY3-1", "A0A9J7F4Q2-1", "A0A9J7H7U2-1", "G3GW97-1", "A0A9J7K418-1", "A0A8C2QEV4-1", "A0A9J7FCD6-1", "A0A9J7JMD0-1", "A0A9J7K9Z1-1", "A0A9J7K3M9-1", "A0A8C2ME21-1", "A0A061I233-1", "A0A3L7H955-1", "A0A8C2MJ36-1", "A0A9J7FDQ9-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HWM0", "gene_name": "LOC113837706", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061HWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HWM0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061HWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HWM0" } ] } ] }, { "uniprot_ac": "A0A061HZZ7", "gene_name": "Rab9b", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061HZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZZ7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061HZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZZ7" } ] } ] }, { "uniprot_ac": "A0A061I233", "gene_name": "Rabl3", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061I233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I233" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061I233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I233" } ] } ] }, { "uniprot_ac": "A0A061I5F7", "gene_name": "Rac1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061I5F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I5F7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061I5F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I5F7" } ] } ] }, { "uniprot_ac": "A0A061I5K5", "gene_name": "Rasl11a", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061I5K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I5K5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061I5K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I5K5" } ] } ] }, { "uniprot_ac": "A0A061IFE4", "gene_name": "Rab24", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061IFE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IFE4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061IFE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IFE4" } ] } ] }, { "uniprot_ac": "A0A061IH58", "gene_name": "Rab19", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061IH58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IH58" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061IH58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IH58" } ] } ] }, { "uniprot_ac": "A0A061INW8", "gene_name": "Nras", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061INW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061INW8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061INW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061INW8" } ] } ] }, { "uniprot_ac": "A0A3L7GXQ2", "gene_name": "LOC113838564", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3L7GXQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GXQ2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3L7GXQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GXQ2" } ] } ] }, { "uniprot_ac": "A0A3L7H955", "gene_name": "Rab43", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3L7H955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H955" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3L7H955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H955" } ] } ] }, { "uniprot_ac": "A0A3L7HA69", "gene_name": "Rab37", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3L7HA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HA69" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3L7HA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HA69" } ] } ] }, { "uniprot_ac": "A0A3L7HQ44", "gene_name": "Rac1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3L7HQ44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQ44" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3L7HQ44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQ44" } ] } ] }, { "uniprot_ac": "A0A3L7HXE9", "gene_name": "Rab30", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3L7HXE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HXE9" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3L7HXE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HXE9" } ] } ] }, { "uniprot_ac": "A0A3L7IA35", "gene_name": "Rab42", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3L7IA35", "database": 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFS0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFS0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766444", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766444", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFS0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFS0" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFS0", "url": 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{ "name": "40S ribosomal protein S6-like", "type": "synonym", "evidence": [ { "id": "XP_035309662", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309662" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 6% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276949.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309662", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309662" } ] }, { "annotation": "Component of the 40S small ribosomal subunit. Plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFS4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFS4#function" }, { "database": "UniProtKB", "id": "ARBA00056579", "url": "https://www.uniprot.org/uniprotkb/ARBA00056579#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7HFS4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HFS4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": 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